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Combining his knowledge, his passion for learning and teaching and his will to contribute, Guillem participated in many collaborations during his PhD and was deeply involved in the training of the newcomers to the lab in the early years of the Dynamic Structural Biology Group at ITQB.
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PhD holder since early 2024, he is now involved in the Sales and Scientific Project Development for a Swiss multinational company
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## Research & Interests
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>- Structural biology (SAXS, NMR)
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>- Protein Biochemistry
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>- Virulence mechanisms
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>- Teamwork and Collaboration
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## Current position
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>Sales Manager at [Kuhner Shaker](https://kuhner.com)
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## Links
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>[<img src="/assets/images/icons/linkedin_icon.png" alt="linkedin" width="20" height="20">](https://www.linkedin.com/in/ghernandezgras)
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>[<img src="/assets/images/icons/ciencia-vitae_icon.png" alt="gscholar" width="40" height="20">](https://www.cienciavitae.pt/portal/611C-6209-D3CB)
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## Selected publications
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**.** **Hernandez G**, Martins ML, Fernandes NP, Veloso T, Lopes J, Gomes, T *, Cordeiro,TN * (2025) **Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation.** *Nucleic Acids Res.* Jun 6;53(11).[link](https://doi.org/10.1093/nar/gkaf502)
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>**.** **Hernandez G**, Martins ML, Fernandes NP, Veloso T, Lopes J, Gomes, T *, Cordeiro,TN * (2025) **Dynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation.** *Nucleic Acids Res.* Jun 6;53(11).[link](https://doi.org/10.1093/nar/gkaf502)
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<p align="center">
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<a href="https://doi.org/10.1093/nar/gkaf502" >
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<img src="/assets/images/thumbnail/pub21-thumbnail.png" alt="N-Protein" style="width: 90%; max-width: 100%; height: auto;" />
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</a>
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</p>
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**.** Vieira,M.F.M., **Hernandez,G.**, Zhong,Q., Arbesú,M., Veloso,T., Gomes,T., Martins,M.L., Monteiro,H., Frazão,C., Frankel,G., Zanzoni, A., Cordeiro, T.N.* (2024) **The pathogen-encoded signalling receptor Tir exploits host-like intrinsic disorder for infection.** *Commun. Biol.*, 7, 179. [link](https://doi.org/10.1038/s42003-024-05856-9)
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>**.** Vieira,M.F.M., **Hernandez,G.**, Zhong,Q., Arbesú,M., Veloso,T., Gomes,T., Martins,M.L., Monteiro,H., Frazão,C., Frankel,G., Zanzoni, A., Cordeiro, T.N.* (2024) **The pathogen-encoded signalling receptor Tir exploits host-like intrinsic disorder for infection.** *Commun. Biol.*, 7, 179. [link](https://doi.org/10.1038/s42003-024-05856-9)
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<p align="center">
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<a href="https://doi.org/10.1038/s42003-024-05856-9" >
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<img src="/assets/images/thumbnail/pub19-thumbnail.png" alt="Publication 19" style="width: 90%; max-width: 100%; height: auto;" />
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</a>
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</p>
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**.** Marini,E., Olivença,C., Ramalhete,S., Aguirre,A.M., Ingle,P., Melo,M.N., Antunes,W., Minton,N.P., **Hernandez,G.**, Cordeiro,T.N., et al. (2023) **A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.** *PLoS Pathog.*, 19, e1011741. [link](https://doi.org/10.1371/journal.ppat.1011741)
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**.** Pinto,D., Gonçalo,R., Louro,M., Silva,M.S., **Hernandez,G.**, Cordeiro,T.N., Cordeiro,C. and São-José,C. (2022) **On the Occurrence and Multimerization of Two-Polypeptide Phage Endolysins Encoded in Single Genes.** *Microbiol. Spectr.*, 10, e0103722. [link](https://doi.org/10.1128/spectrum.01037-22)
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## Research Interests
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- Structural biology (SAXS, NMR)
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- Protein Biochemistry
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- Virulence mechanisms
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- Teamwork and Collaboration
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## Current position
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Sales Manager at [Kuhner Shaker](https://kuhner.com)
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## Links
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>[<img src="/assets/images/icons/linkedin_icon.png" alt="linkedin" width="20" height="20">](https://www.linkedin.com/in/ghernandezgras)
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>[<img src="/assets/images/icons/ciencia-vitae_icon.png" alt="gscholar" width="40" height="20">](https://www.cienciavitae.pt/portal/611C-6209-D3CB)
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>**.** Marini,E., Olivença,C., Ramalhete,S., Aguirre,A.M., Ingle,P., Melo,M.N., Antunes,W., Minton,N.P., **Hernandez,G.**, Cordeiro,T.N., et al. (2023) **A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile.** *PLoS Pathog.*, 19, e1011741. [link](https://doi.org/10.1371/journal.ppat.1011741)
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>**.** Pinto,D., Gonçalo,R., Louro,M., Silva,M.S., **Hernandez,G.**, Cordeiro,T.N., Cordeiro,C. and São-José,C. (2022) **On the Occurrence and Multimerization of Two-Polypeptide Phage Endolysins Encoded in Single Genes.** *Microbiol. Spectr.*, 10, e0103722. [link](https://doi.org/10.1128/spectrum.01037-22)
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