Posted by
- {% if post.author %}
- {{ post.author }}
- {% else %}
- {{ site.author }}
- {% endif %}
- on
- {{ post.date | date: '%B %d, %Y' }} · {% include read_time.html content=post.content %}
-
Posted by
- {% if page.author %}{{ page.author }}{% else %}{{ site.author }}{% endif %}
- on {{ page.date | date: '%B %d, %Y' }} · {% include read_time.html
- content=page.content %}
+ Posted by Johanna Diaz
diff --git a/_posts/.html b/_posts/.html
new file mode 100644
index 0000000000..258dc4a308
--- /dev/null
+++ b/_posts/.html
@@ -0,0 +1,62 @@
+---
+layout: post
+title: "Wine Quality Predictor"
+subtitle: "Exploring wine quality through analysis and prediction"
+date: 2023-06-28 23:45:13 -0400
+background: '/img/posts/03.jpg'
+---
+
+This project aims to apply Machine Learning techniques to develop predictive models that can predict the quality of wine based on its physicochemical attributes. To achieve this, visualization and exploratory analysis techniques will be explored to understand the distribution of the attributes and their impact on prediction. Additionally, the crucial role of data preprocessing and transformation in the modeling phase will be highlighted.
+
+Description of Dataset
+
+Source: This dataset was created by P. Cortez, A. Cerdeira, F. Almeida, T. Matos, and J. Reis. The "Wine Quality" dataset is available in the UCI Machine Learning Repository.
+
+The "Wine Quality" dataset is commonly used in classification and regression problems to predict wine quality. It was collected to evaluate the quality of white and red wines based on physicochemical attributes. The inputs were gathered through physicochemical tests, and the output is based on sensory data obtained from evaluations conducted by wine experts. Each expert rated the wine quality on a scale from 0 (very poor) to 10 (excellent).
+
+ Attribute Description:The "Wine Quality" dataset consists of instances of white and red wines, with a total of 11 numerical attributes. These attributes include characteristics such as acidity, sugar levels, sulfates, and alcohol content. The wine quality is represented by a categorical target variable.
+
+Input Attributes (x):
+
+ - Fixed acidity (Acidez fija): g/dm³ (float)
+ - Volatile acidity (Acidez volátil): g/dm³ (float)
+ - Citric acid (Ácido cítrico): g/dm³ (float)
+ - Residual sugar (Azúcar residual): g/dm³ (float)
+ - Chlorides (Cloruros): g/dm³ (float)
+ - Free sulfur dioxide (Dióxido de azufre libre): mg/dm³ (float)
+ - Total sulfur dioxide (Dióxido de azufre total): mg/dm³ (float)
+ - Density (Densidad): g/cm³ (float)
+ - pH: (float)
+ - Sulphates (Sulfatos): g/dm³ (float)
+ - Alcohol (Alcohol): % vol (float)
+
+
+Output Attributes(y):
+
+ - Wine Quality: It is evaluated on a discrete scale of 0 to 10, where a higher value indicates better quality
+
+Exploratory Data Analysis
+
+Before diving into the predictive modeling, an initial step is to perform an Exploratory Data Analysis (EDA). For this purpose, you can load the dataset into your working environment, such as Python with Pandas, and execute the following tasks:
+
+ This repository contains the results of a comprehensive analysis of a white wine dataset provided by the reference researchers. The analysis involved three key stages: data preprocessing, modeling and evaluation, and performance improvement strategies.
+
+ Data Preprocessing
+ In the data preprocessing phase, we applied essential techniques, such as feature scaling using StandardScaler. This ensured that all features contributed equally to the modeling process, thus avoiding the dominance of certain attributes over others.
+
+ Modeling
+ In the modeling stage, we deliberately selected four specific algorithms: Decision Tree, Random Forest, SVM, and K-NN. The choice of these algorithms was based on their demonstrated ability to address classification problems in complex datasets. It is important to note that, although some algorithms were shared with the reference study, the methodologies differed in aspects such as hyperparameter tuning and how class imbalance was addressed.
+
+ Evaluation
+ The reference study provided results that served as a starting point for model evaluation. It was observed that, despite achieving acceptable levels of accuracy, class imbalance affected the model's ability to generalize to minority classes. This finding was crucial in determining the need to implement an oversampling strategy.
+
+ Performance Improvement
+ The oversampling strategy was the key element in significantly improving the model's performance. By increasing the number of instances in the minority classes, the class distribution was balanced, allowing the model to learn more effectively from all classes. This resulted in a noticeable increase in accuracy on the test set, reaching an impressive 92%.
+
+ Conclusion
+ While both methodologies shared the use of some common algorithms, they differed in their approach to addressing class imbalance and the specific model configurations. This distinction is fundamental and highlights the importance of adapting methodologies to the unique characteristics of each dataset and problem.
+
+ For more details, refer to the complete analysis and code in this repository.
+ Open in Google Colab
+
+Photographs by Unsplash.
diff --git a/_posts/2020-01-26-dinosaurs.html b/_posts/2020-01-26-dinosaurs.html
deleted file mode 100644
index fc3c9f0b6a..0000000000
--- a/_posts/2020-01-26-dinosaurs.html
+++ /dev/null
@@ -1,40 +0,0 @@
----
-layout: post
-title: "Dinosaurs are extinct today"
-subtitle: "because they lacked opposable thumbs and the brainpower to build a space program."
-date: 2020-01-26 23:45:13 -0400
-background: '/img/posts/01.jpg'
----
-
-Never in all their history have men been able truly to conceive of the world as one: a single sphere, a globe, having the qualities of a globe, a round earth in which all the directions eventually meet, in which there is no center because every point, or none, is center — an equal earth which all men occupy as equals. The airman's earth, if free men make it, will be truly round: a globe in practice, not in theory.
-
-Science cuts two ways, of course; its products can be used for both good and evil. But there's no turning back from science. The early warnings about technological dangers also come from science.
-
-What was most significant about the lunar voyage was not that man set foot on the Moon but that they set eye on the earth.
-
-A Chinese tale tells of some men sent to harm a young girl who, upon seeing her beauty, become her protectors rather than her violators. That's how I felt seeing the Earth for the first time. I could not help but love and cherish her.
-
-For those who have seen the Earth from space, and for the hundreds and perhaps thousands more who will, the experience most certainly changes your perspective. The things that we share in our world are far more valuable than those which divide us.
-
-The Final Frontier
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-The dreams of yesterday are the hopes of today and the reality of tomorrow. Science has not yet mastered prophecy. We predict too much for the next year and yet far too little for the next ten.
-
-Spaceflights cannot be stopped. This is not the work of any one man or even a group of men. It is a historical process which mankind is carrying out in accordance with the natural laws of human development.
-
-Reaching for the Stars
-
-As we got further and further away, it [the Earth] diminished in size. Finally it shrank to the size of a marble, the most beautiful you can imagine. That beautiful, warm, living object looked so fragile, so delicate, that if you touched it with a finger it would crumble and fall apart. Seeing this has to change a man.
-
-
-To go places and do things that have never been done before – that’s what living is all about.
-
-Space, the final frontier. These are the voyages of the Starship Enterprise. Its five-year mission: to explore strange new worlds, to seek out new life and new civilizations, to boldly go where no man has gone before.
-
-As I stand out here in the wonders of the unknown at Hadley, I sort of realize there’s a fundamental truth to our nature, Man must explore, and this is exploration at its greatest.
-
-Placeholder text by Space Ipsum. Photographs by Unsplash.
diff --git a/_posts/2020-01-27-dreams.html b/_posts/2020-01-27-dreams.html
deleted file mode 100644
index f687623ea2..0000000000
--- a/_posts/2020-01-27-dreams.html
+++ /dev/null
@@ -1,39 +0,0 @@
----
-layout: post
-title: "The dreams of yesterday are the hopes of today and the reality of tomorrow."
-date: 2020-01-27 23:45:13 -0400
-background: '/img/posts/02.jpg'
----
-
-Never in all their history have men been able truly to conceive of the world as one: a single sphere, a globe, having the qualities of a globe, a round earth in which all the directions eventually meet, in which there is no center because every point, or none, is center — an equal earth which all men occupy as equals. The airman's earth, if free men make it, will be truly round: a globe in practice, not in theory.
-
-Science cuts two ways, of course; its products can be used for both good and evil. But there's no turning back from science. The early warnings about technological dangers also come from science.
-
-What was most significant about the lunar voyage was not that man set foot on the Moon but that they set eye on the earth.
-
-A Chinese tale tells of some men sent to harm a young girl who, upon seeing her beauty, become her protectors rather than her violators. That's how I felt seeing the Earth for the first time. I could not help but love and cherish her.
-
-For those who have seen the Earth from space, and for the hundreds and perhaps thousands more who will, the experience most certainly changes your perspective. The things that we share in our world are far more valuable than those which divide us.
-
-The Final Frontier
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-The dreams of yesterday are the hopes of today and the reality of tomorrow. Science has not yet mastered prophecy. We predict too much for the next year and yet far too little for the next ten.
-
-Spaceflights cannot be stopped. This is not the work of any one man or even a group of men. It is a historical process which mankind is carrying out in accordance with the natural laws of human development.
-
-Reaching for the Stars
-
-As we got further and further away, it [the Earth] diminished in size. Finally it shrank to the size of a marble, the most beautiful you can imagine. That beautiful, warm, living object looked so fragile, so delicate, that if you touched it with a finger it would crumble and fall apart. Seeing this has to change a man.
-
-
-To go places and do things that have never been done before – that’s what living is all about.
-
-Space, the final frontier. These are the voyages of the Starship Enterprise. Its five-year mission: to explore strange new worlds, to seek out new life and new civilizations, to boldly go where no man has gone before.
-
-As I stand out here in the wonders of the unknown at Hadley, I sort of realize there’s a fundamental truth to our nature, Man must explore, and this is exploration at its greatest.
-
-Placeholder text by Space Ipsum. Photographs by Unsplash.
diff --git a/_posts/2020-01-28-exploration.html b/_posts/2020-01-28-exploration.html
deleted file mode 100644
index ec94119725..0000000000
--- a/_posts/2020-01-28-exploration.html
+++ /dev/null
@@ -1,40 +0,0 @@
----
-layout: post
-title: "Failure is not an option"
-subtitle: "Many say exploration is part of our destiny, but it’s actually our duty to future generations."
-date: 2020-01-28 23:45:13 -0400
-background: '/img/posts/03.jpg'
----
-
-Never in all their history have men been able truly to conceive of the world as one: a single sphere, a globe, having the qualities of a globe, a round earth in which all the directions eventually meet, in which there is no center because every point, or none, is center — an equal earth which all men occupy as equals. The airman's earth, if free men make it, will be truly round: a globe in practice, not in theory.
-
-Science cuts two ways, of course; its products can be used for both good and evil. But there's no turning back from science. The early warnings about technological dangers also come from science.
-
-What was most significant about the lunar voyage was not that man set foot on the Moon but that they set eye on the earth.
-
-A Chinese tale tells of some men sent to harm a young girl who, upon seeing her beauty, become her protectors rather than her violators. That's how I felt seeing the Earth for the first time. I could not help but love and cherish her.
-
-For those who have seen the Earth from space, and for the hundreds and perhaps thousands more who will, the experience most certainly changes your perspective. The things that we share in our world are far more valuable than those which divide us.
-
-The Final Frontier
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-The dreams of yesterday are the hopes of today and the reality of tomorrow. Science has not yet mastered prophecy. We predict too much for the next year and yet far too little for the next ten.
-
-Spaceflights cannot be stopped. This is not the work of any one man or even a group of men. It is a historical process which mankind is carrying out in accordance with the natural laws of human development.
-
-Reaching for the Stars
-
-As we got further and further away, it [the Earth] diminished in size. Finally it shrank to the size of a marble, the most beautiful you can imagine. That beautiful, warm, living object looked so fragile, so delicate, that if you touched it with a finger it would crumble and fall apart. Seeing this has to change a man.
-
-
-To go places and do things that have never been done before – that’s what living is all about.
-
-Space, the final frontier. These are the voyages of the Starship Enterprise. Its five-year mission: to explore strange new worlds, to seek out new life and new civilizations, to boldly go where no man has gone before.
-
-As I stand out here in the wonders of the unknown at Hadley, I sort of realize there’s a fundamental truth to our nature, Man must explore, and this is exploration at its greatest.
-
-Placeholder text by Space Ipsum. Photographs by Unsplash.
diff --git a/_posts/2020-01-29-prophecy.html b/_posts/2020-01-29-prophecy.html
deleted file mode 100644
index 65704ea439..0000000000
--- a/_posts/2020-01-29-prophecy.html
+++ /dev/null
@@ -1,40 +0,0 @@
----
-layout: post
-title: "Science has not yet mastered prophecy"
-subtitle: "We predict too much for the next year and yet far too little for the next ten."
-date: 2020-01-29 23:45:13 -0400
-background: '/img/posts/04.jpg'
----
-
-Never in all their history have men been able truly to conceive of the world as one: a single sphere, a globe, having the qualities of a globe, a round earth in which all the directions eventually meet, in which there is no center because every point, or none, is center — an equal earth which all men occupy as equals. The airman's earth, if free men make it, will be truly round: a globe in practice, not in theory.
-
-Science cuts two ways, of course; its products can be used for both good and evil. But there's no turning back from science. The early warnings about technological dangers also come from science.
-
-What was most significant about the lunar voyage was not that man set foot on the Moon but that they set eye on the earth.
-
-A Chinese tale tells of some men sent to harm a young girl who, upon seeing her beauty, become her protectors rather than her violators. That's how I felt seeing the Earth for the first time. I could not help but love and cherish her.
-
-For those who have seen the Earth from space, and for the hundreds and perhaps thousands more who will, the experience most certainly changes your perspective. The things that we share in our world are far more valuable than those which divide us.
-
-The Final Frontier
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-The dreams of yesterday are the hopes of today and the reality of tomorrow. Science has not yet mastered prophecy. We predict too much for the next year and yet far too little for the next ten.
-
-Spaceflights cannot be stopped. This is not the work of any one man or even a group of men. It is a historical process which mankind is carrying out in accordance with the natural laws of human development.
-
-Reaching for the Stars
-
-As we got further and further away, it [the Earth] diminished in size. Finally it shrank to the size of a marble, the most beautiful you can imagine. That beautiful, warm, living object looked so fragile, so delicate, that if you touched it with a finger it would crumble and fall apart. Seeing this has to change a man.
-
-
-To go places and do things that have never been done before – that’s what living is all about.
-
-Space, the final frontier. These are the voyages of the Starship Enterprise. Its five-year mission: to explore strange new worlds, to seek out new life and new civilizations, to boldly go where no man has gone before.
-
-As I stand out here in the wonders of the unknown at Hadley, I sort of realize there’s a fundamental truth to our nature, Man must explore, and this is exploration at its greatest.
-
-Placeholder text by Space Ipsum. Photographs by Unsplash.
diff --git a/_posts/2020-01-30-heartbeats.html b/_posts/2020-01-30-heartbeats.html
deleted file mode 100644
index a444e6cd18..0000000000
--- a/_posts/2020-01-30-heartbeats.html
+++ /dev/null
@@ -1,39 +0,0 @@
----
-layout: post
-title: "I believe every human has a finite number of heartbeats. I don't intend to waste any of mine."
-date: 2020-01-30 23:45:13 -0400
-background: '/img/posts/05.jpg'
----
-
-Never in all their history have men been able truly to conceive of the world as one: a single sphere, a globe, having the qualities of a globe, a round earth in which all the directions eventually meet, in which there is no center because every point, or none, is center — an equal earth which all men occupy as equals. The airman's earth, if free men make it, will be truly round: a globe in practice, not in theory.
-
-Science cuts two ways, of course; its products can be used for both good and evil. But there's no turning back from science. The early warnings about technological dangers also come from science.
-
-What was most significant about the lunar voyage was not that man set foot on the Moon but that they set eye on the earth.
-
-A Chinese tale tells of some men sent to harm a young girl who, upon seeing her beauty, become her protectors rather than her violators. That's how I felt seeing the Earth for the first time. I could not help but love and cherish her.
-
-For those who have seen the Earth from space, and for the hundreds and perhaps thousands more who will, the experience most certainly changes your perspective. The things that we share in our world are far more valuable than those which divide us.
-
-The Final Frontier
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-The dreams of yesterday are the hopes of today and the reality of tomorrow. Science has not yet mastered prophecy. We predict too much for the next year and yet far too little for the next ten.
-
-Spaceflights cannot be stopped. This is not the work of any one man or even a group of men. It is a historical process which mankind is carrying out in accordance with the natural laws of human development.
-
-Reaching for the Stars
-
-As we got further and further away, it [the Earth] diminished in size. Finally it shrank to the size of a marble, the most beautiful you can imagine. That beautiful, warm, living object looked so fragile, so delicate, that if you touched it with a finger it would crumble and fall apart. Seeing this has to change a man.
-
-
-To go places and do things that have never been done before – that’s what living is all about.
-
-Space, the final frontier. These are the voyages of the Starship Enterprise. Its five-year mission: to explore strange new worlds, to seek out new life and new civilizations, to boldly go where no man has gone before.
-
-As I stand out here in the wonders of the unknown at Hadley, I sort of realize there’s a fundamental truth to our nature, Man must explore, and this is exploration at its greatest.
-
-Placeholder text by Space Ipsum. Photographs by Unsplash.
diff --git a/_posts/2020-01-31-man-must-explore.html b/_posts/2020-01-31-man-must-explore.html
deleted file mode 100644
index 4dd948b4d7..0000000000
--- a/_posts/2020-01-31-man-must-explore.html
+++ /dev/null
@@ -1,40 +0,0 @@
----
-layout: post
-title: "Man must explore, and this is exploration at its greatest"
-subtitle: "Problems look mighty small from 150 miles up"
-date: 2020-01-31 10:45:13 -0400
-background: '/img/posts/06.jpg'
----
-
-Never in all their history have men been able truly to conceive of the world as one: a single sphere, a globe, having the qualities of a globe, a round earth in which all the directions eventually meet, in which there is no center because every point, or none, is center — an equal earth which all men occupy as equals. The airman's earth, if free men make it, will be truly round: a globe in practice, not in theory.
-
-Science cuts two ways, of course; its products can be used for both good and evil. But there's no turning back from science. The early warnings about technological dangers also come from science.
-
-What was most significant about the lunar voyage was not that man set foot on the Moon but that they set eye on the earth.
-
-A Chinese tale tells of some men sent to harm a young girl who, upon seeing her beauty, become her protectors rather than her violators. That's how I felt seeing the Earth for the first time. I could not help but love and cherish her.
-
-For those who have seen the Earth from space, and for the hundreds and perhaps thousands more who will, the experience most certainly changes your perspective. The things that we share in our world are far more valuable than those which divide us.
-
-The Final Frontier
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-There can be no thought of finishing for ‘aiming for the stars.’ Both figuratively and literally, it is a task to occupy the generations. And no matter how much progress one makes, there is always the thrill of just beginning.
-
-The dreams of yesterday are the hopes of today and the reality of tomorrow. Science has not yet mastered prophecy. We predict too much for the next year and yet far too little for the next ten.
-
-Spaceflights cannot be stopped. This is not the work of any one man or even a group of men. It is a historical process which mankind is carrying out in accordance with the natural laws of human development.
-
-Reaching for the Stars
-
-As we got further and further away, it [the Earth] diminished in size. Finally it shrank to the size of a marble, the most beautiful you can imagine. That beautiful, warm, living object looked so fragile, so delicate, that if you touched it with a finger it would crumble and fall apart. Seeing this has to change a man.
-
-
-To go places and do things that have never been done before – that’s what living is all about.
-
-Space, the final frontier. These are the voyages of the Starship Enterprise. Its five-year mission: to explore strange new worlds, to seek out new life and new civilizations, to boldly go where no man has gone before.
-
-As I stand out here in the wonders of the unknown at Hadley, I sort of realize there’s a fundamental truth to our nature, Man must explore, and this is exploration at its greatest.
-
-Placeholder text by Space Ipsum. Photographs by Unsplash.
diff --git a/_posts/2023-04-3-Bioinformatics.html b/_posts/2023-04-3-Bioinformatics.html
new file mode 100644
index 0000000000..1a5ec49aad
--- /dev/null
+++ b/_posts/2023-04-3-Bioinformatics.html
@@ -0,0 +1,70 @@
+---
+layout: post
+title: "Bioinformatics: high-throughput methods"
+subtitle: "High-throughput pharmacological screening consists of testing large collections of chemical compounds or natural products to identify biologically active molecules."
+date: 2023-04-3 10:45:13 -0400
+background: '/img/posts/07.avif'
+---
+
+Executive Summary
+Abstract
+ Dengue is an acute febrile illness caused by the Dengue virus (DENV), with a high number of cases worldwide. There is no available treatment that directly affects the virus or the viral cycle. The objective of this study was to identify a compound derived from natural products that interacts with the NS5 protein of the dengue virus through virtual screening and evaluate its in vitro antiviral effect on DENV-2.
+
+ Methods
+
+ Molecular Docking: Molecular docking was performed on NS5 using AutoDock Vina software to identify potential compounds that could interact with the NS5 protein.
+
+
+ Selection of Compounds: Compounds with physicochemical and pharmacological properties of interest were selected based on the results of molecular docking.
+
+
+ Antiviral Effect Evaluation: The preliminary antiviral effect was evaluated through several methods:
+
+
+ -
+ NS1 Protein Expression: The effect on viral replication was assessed by measuring the expression of the NS1 protein.
+
+ -
+ NS5 Production: The effect on viral genome replication and/or translation was determined by measuring NS5 production using DENV-2 Huh-7 replicon through ELISA.
+
+ -
+ Viral RNA Quantification: Viral RNA quantification was performed using RT-qPCR to assess the impact on viral genome replication.
+
+
+
+ Results
+ The in silico strategy proved effective in finding a compound (M78) with an indole-like structure.
+
+ Antiviral Effect: Treatment with M78 at 50 µM reduced the expression of the NS5 protein by 70% and decreased viral RNA by 1.7 times, suggesting that M78 is involved in the replication and/or translation of the viral genome.
+
+
+Bioinformatics: In Silico Assays
+
+ Virtual Screening of Natural Compound Derivatives on DENV NS5 Protein
+ As part of my data science experience, I conducted virtual screening of natural compound derivatives on the DENV NS5 protein. The objective of this study was to identify compounds that could interact with the NS5 protein, a key component of the Dengue virus. This research utilized cutting-edge in silico techniques to identify potential antiviral compounds.
+
+ The virtual screening involved:
+
+ - Obtaining the structures of NS5 proteins from the four DENV serotypes.
+ - Selecting cavities for interaction, such as the substrate binding site and RNA tunnel.
+ - Re-docking ligands SAH and 68E to obtain binding energy values.
+ - Performing eight virtual screenings, two for each serotype.
+ - Utilizing a library of 190,090 natural compound derivatives available on the DrugDiscovery@TACC web portal.
+ - Employing AutoDock Vina 1.1 software for virtual screening calculations.
+
+
+ Selection of Compounds by Interaction on NS5 of DENV
+ After the virtual screening, the selection of compounds was a crucial step. Compounds were chosen based on their ability to bind to NS5 in all four serotypes of the Dengue virus. The selection process involved the following criteria:
+
+
+ - Assessing aqueous solubility using the SwissADME web server.
+ - Checking compliance with Lipinski's rules to evaluate drug-likeness.
+ - Predicting possible toxicological risks using the ProTox-II web server.
+ - 3D visualization of protein-ligand complexes using the Chimera v1.13.1 program.
+
+ This experience showcases the use of advanced in silico tools and computational methods to identify potential antiviral compounds, emphasizing the importance of data science in drug discovery and research.
+
+For more details, refer to the complete analysis and code in this repository.
+Open in MPDI
+
+Photographs by Unsplash.
\ No newline at end of file
diff --git a/_posts/2023-04-3-Energy Efficiency.html b/_posts/2023-04-3-Energy Efficiency.html
new file mode 100644
index 0000000000..f587f6bd51
--- /dev/null
+++ b/_posts/2023-04-3-Energy Efficiency.html
@@ -0,0 +1,67 @@
+---
+layout: post
+title: "Energy Efficiency in Residential Buildings"
+subtitle: "Exploring the Relationship Between Building Design and Energy Efficiency"
+date: 2023-04-3 10:45:13 -0400
+background: '/img/posts/06.jpg'
+---
+
+Executive Summary
+
+This project focuses on the analysis and optimization of energy efficiency in residential buildings using the mentioned dataset. The physical and design characteristics of buildings will be explored to understand their impact on heating load. For this purpose, models will be developed to predict the required heating load based on specific building characteristics. Additionally, the aim is to identify key attributes that influence the energy efficiency of buildings and provide practical recommendations for optimizing the design and energy management of residential buildings.
+
+Description of Dataset
+
+Source: This dataset was created by Angeliki Xifara and Athanasios Tsanas from the University of Sheffield, United Kingdom.
+
+The "Energy Efficiency" dataset is available in the UCI Machine Learning Repository. The "Energy Efficiency" dataset is commonly used in regression problems to predict energy efficiency in buildings.
+
+ Attribute Description: The "Energy Efficiency" dataset, which was collected to evaluate the energy performance of buildings, consists of 768 instances (m). Each building is represented by eight input attributes (independent variables) related to its design and geometry, and two output attributes (dependent variables).
+
+Input Attributes (x):
+
+
+ - Relative Compactness: Relative compactness of the building
+ - Surface Area: Total surface area of the building
+ - Wall Area: Wall area of the building
+ - Roof Area: Roof area of the building
+ - Overall Height: Overall height of the building
+ - Orientation: Orientation of the building
+ - Glazing Area: Relative glazing area
+ - Glazing Area Distribution: Distribution of glazing area
+
+Output Attributes(y):
+
+ - Heating Load: Heating load of the building
+ - Cooling Load: Cooling load of the building
+
+Exploratory Data Analysis
+
+
+Methodology and Modeling
+A methodology consisting of two phases was implemented: modeling and evaluation. During the modeling phase, several regression models were trained, including Linear Regression, Theil-Sen Regressor, Random Forest Regressor, Support Vector Regressor (SVR), and Decision Tree Regressor. These models were trained independently to predict both heating load and cooling load.
+
+Modeling Results
+In the modeling phase, notable trends in model performance for both variables were observed:
+
+
+ - For heating load prediction, the Random Forest Regressor model exhibited outstanding performance, with a Mean Squared Error (MSE) close to zero and an R-squared (R2) almost equal to 1. This indicates a nearly perfect fit to the training data, although overfitting is a possibility. The Linear Regression, Theil-Sen Regressor, and SVR models also showed good performance, though slightly behind the Random Forest model.
+ - Regarding cooling load prediction, similar patterns were observed. The Random Forest Regressor model excelled with very low MSE and an R2 close to 1. The other models also demonstrated good performance, but not as remarkable as the Random Forest model.
+
+
+Evaluation Results
+In the evaluation phase, the trends observed in the modeling phase were confirmed:
+
+
+ - For heating load prediction, the Random Forest Regressor model continued to exhibit exceptional performance, with low MSE and high R2. The Decision Tree Regressor model also showed good performance in the evaluation phase.
+ - For cooling load prediction, a similar pattern was observed, with the Random Forest Regressor model remaining the leader, followed by the Decision Tree Regressor model.
+
+
+Conclusions and Recommendations
+Based on the results obtained, it can be concluded that the Random Forest Regressor model is the most promising for this specific dataset. However, it is important to remember that results may vary in different datasets, so cross-validation is recommended, and model hyperparameters should be adjusted for more robust results.
+
+Furthermore, it is suggested to explore other feature engineering techniques and consider the inclusion of more predictor variables to further enhance model performance. This project provides a solid foundation for energy load prediction in heating and cooling systems and can be scaled and adapted for future applications in energy efficiency in buildings.
+For more details, refer to the complete analysis and code in this repository.
+Open in Google Colab
+
+Photographs by Unsplash.
\ No newline at end of file
diff --git a/_posts/2023-06-28-WIne Quality.html b/_posts/2023-06-28-WIne Quality.html
new file mode 100644
index 0000000000..4fa00a57dd
--- /dev/null
+++ b/_posts/2023-06-28-WIne Quality.html
@@ -0,0 +1,62 @@
+---
+layout: post
+title: "Wine Quality Predictor"
+subtitle: "Exploring wine quality through analysis and prediction"
+date: 2023-06-28 23:45:13 -0400
+background: '/img/posts/03.jpg'
+---
+
+This project aims to apply Machine Learning techniques to develop predictive models that can predict the quality of wine based on its physicochemical attributes. To achieve this, visualization and exploratory analysis techniques will be explored to understand the distribution of the attributes and their impact on prediction. Additionally, the crucial role of data preprocessing and transformation in the modeling phase will be highlighted.
+
+Description of Dataset
+
+Source: This dataset was created by P. Cortez, A. Cerdeira, F. Almeida, T. Matos, and J. Reis. The "Wine Quality" dataset is available in the UCI Machine Learning Repository.
+
+The "Wine Quality" dataset is commonly used in classification and regression problems to predict wine quality. It was collected to evaluate the quality of white and red wines based on physicochemical attributes. The inputs were gathered through physicochemical tests, and the output is based on sensory data obtained from evaluations conducted by wine experts. Each expert rated the wine quality on a scale from 0 (very poor) to 10 (excellent).
+
+ Attribute Description:The "Wine Quality" dataset consists of instances of white and red wines, with a total of 11 numerical attributes. These attributes include characteristics such as acidity, sugar levels, sulfates, and alcohol content. The wine quality is represented by a categorical target variable.
+
+Input Attributes (x):
+
+ - Fixed acidity (Acidez fija): g/dm³ (float)
+ - Volatile acidity (Acidez volátil): g/dm³ (float)
+ - Citric acid (Ácido cítrico): g/dm³ (float)
+ - Residual sugar (Azúcar residual): g/dm³ (float)
+ - Chlorides (Cloruros): g/dm³ (float)
+ - Free sulfur dioxide (Dióxido de azufre libre): mg/dm³ (float)
+ - Total sulfur dioxide (Dióxido de azufre total): mg/dm³ (float)
+ - Density (Densidad): g/cm³ (float)
+ - pH: (float)
+ - Sulphates (Sulfatos): g/dm³ (float)
+ - Alcohol (Alcohol): % vol (float)
+
+
+Output Attributes(y):
+
+ - Wine Quality: It is evaluated on a discrete scale of 0 to 10, where a higher value indicates better quality
+
+Exploratory Data Analysis
+
+Before diving into the predictive modeling, an initial step is to perform an Exploratory Data Analysis (EDA). For this purpose, you can load the dataset into your working environment, such as Python with Pandas, and execute the following tasks:
+
+ This repository contains the results of a comprehensive analysis of a white wine dataset provided by the reference researchers. The analysis involved three key stages: data preprocessing, modeling and evaluation, and performance improvement strategies.
+
+ Data Preprocessing
+ In the data preprocessing phase, we applied essential techniques, such as feature scaling using StandardScaler. This ensured that all features contributed equally to the modeling process, thus avoiding the dominance of certain attributes over others.
+
+ Modeling
+ In the modeling stage, we deliberately selected four specific algorithms: Decision Tree, Random Forest, SVM, and K-NN. The choice of these algorithms was based on their demonstrated ability to address classification problems in complex datasets. It is important to note that, although some algorithms were shared with the reference study, the methodologies differed in aspects such as hyperparameter tuning and how class imbalance was addressed.
+
+ Evaluation
+ The reference study provided results that served as a starting point for model evaluation. It was observed that, despite achieving acceptable levels of accuracy, class imbalance affected the model's ability to generalize to minority classes. This finding was crucial in determining the need to implement an oversampling strategy.
+
+ Performance Improvement
+ The oversampling strategy was the key element in significantly improving the model's performance. By increasing the number of instances in the minority classes, the class distribution was balanced, allowing the model to learn more effectively from all classes. This resulted in a noticeable increase in accuracy on the test set, reaching an impressive 92%.
+
+ Conclusion
+ While both methodologies shared the use of some common algorithms, they differed in their approach to addressing class imbalance and the specific model configurations. This distinction is fundamental and highlights the importance of adapting methodologies to the unique characteristics of each dataset and problem.
+
+ For more details, refer to the complete analysis and code in this repository.
+ Open in Google Colab
+
+Photographs by Unsplash.
diff --git a/about.html b/about.html
index c661ef64e4..868fc631cc 100644
--- a/about.html
+++ b/about.html
@@ -4,9 +4,10 @@
description: This is what I do.
background: '/img/bg-about.jpg'
---
-
-Lorem ipsum dolor sit amet, consectetur adipisicing elit. Sed quisquam ut perspiciatis, repudiandae nulla animi iste vel, praesentium repellendus molestias aliquid consequatur, earum rem qui error voluptates eius enim consequuntur!
-
-Lorem ipsum dolor sit amet, consectetur adipisicing elit. Ex alias, earum consectetur quia natus ducimus voluptate explicabo, hic porro reprehenderit, quasi? Tenetur ipsum distinctio laboriosam perspiciatis officiis dolore, architecto id.
-
-Lorem ipsum dolor sit amet, consectetur adipisicing elit. Totam inventore aspernatur repellendus incidunt adipisci modi voluptates recusandae iste eligendi, repudiandae corporis quod aut, optio! Explicabo quaerat unde voluptatem! Itaque, eum!
+
+
+ As a specialized data science professional, I have a track record of over two years dedicated to scientific data analysis, especially in the biomedical field. My expertise primarily revolves around the advanced application of statistics and modeling using tools such as Python and R. Through a detailed examination of my portfolio, you can appreciate the projects I've undertaken, showcasing my abilities to address complex problems using innovative data science techniques, thereby contributing to the advancement of multidisciplinary knowledge.
+
+
For more details, refer to my CV in Canvas
+
Open in Canvas
+
diff --git a/contact.html b/contact.html
index e23d22616e..09d37786db 100644
--- a/contact.html
+++ b/contact.html
@@ -6,39 +6,32 @@
form: true
---
-Want to get in touch? Fill out the form below to send me a message and I will get back to you as soon as possible!
-