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| 1 | +Name: Epigenomes of the Human Pangenome Reference Consortium (HPRC) Release 2 |
| 2 | +Description: | |
| 3 | + The Human Pangenome Reference Consortium (HPRC) Release 2 represents a landmark achievement in genomics, providing high-quality phased genome assemblies from over 200 individuals with comprehensive functional genomics data. The HPRC Epigenome Browser provides researchers a way to explore all epigenomics data generated by release 2. The HPRC Epigenome Browser (HPRCEB) is a modern, interactive web portal that democratizes access to HPRC Release 2 epigenomics data through an intuitive interface supporting genome selection, data visualization, and bulk download capabilities. The portal integrates genome assemblies, DNA methylation profiles, gene expression data, and chromatin accessibility measurements across diverse populations, enabling researchers to efficiently identify and retrieve datasets matching their specific research needs. |
| 4 | +Contact: dli23@wustl.edu |
| 5 | +ManagedBy: Ting Wang Lab (https://wang.wustl.edu/) |
| 6 | +Documentation: https://epigenome.humanpangenome.org/?tab=tutorials |
| 7 | +UpdateFrequency: Annual. The repository will be updated with each new batch of data as it is generated and released under the next HPRC yearly cycle. |
| 8 | +Tags: |
| 9 | + - biology |
| 10 | + - bioinformatics |
| 11 | + - genetic |
| 12 | + - genomic |
| 13 | + - epigenomics |
| 14 | + - life sciences |
| 15 | + - aws-pds |
| 16 | +License: External data users may freely download, analyze, and publish results based on any HPRC data provided here without restrictions. |
| 17 | +Resources: |
| 18 | + - Description: HPRC Epigenome Browser |
| 19 | + ARN: arn:aws:s3:::hprc-epigenome |
| 20 | + Region: us-west-2 |
| 21 | + Type: S3 Bucket |
| 22 | +DataAtWork: |
| 23 | + Tutorials: |
| 24 | + - Title: | |
| 25 | + "Get To Know A Dataset: HPRC Epigenome" |
| 26 | + URL: https://github.com/twlab/open-data-examples/blob/main/get-to-know-hprc-epigenome.ipynb |
| 27 | + AuthorName: HPRC Epigenome Browser |
| 28 | + AuthorURL: https://epigenome.humanpangenome.org/ |
| 29 | + Publications: |
| 30 | + - Title: A draft human pangenome reference |
| 31 | + URL: https://doi.org/10.1038/s41586-023-05896-x |
| 32 | + AuthorName: Liao, WW., Asri, M., Ebler, J. et al. |
| 33 | + - Title: | |
| 34 | + "Modbed track: Visualization of modified bases in single-molecule sequencing" |
| 35 | + URL: https://www.sciencedirect.com/science/article/pii/S2666979X23002999?via%3Dihub |
| 36 | + AuthorName: Daofeng Li, Xiaoyu Zhuo, Jessica K. Harrison, Shane Liu, Ting Wang |
| 37 | + - Title: WashU Epigenome Browser update 2025 |
| 38 | + URL: https://doi.org/10.1093/nar/gkaf387 |
| 39 | + AuthorName: Chanrung Seng, Shane Liu, Wenjin Zhang, Xiaoyu Zhuo, Daofeng Li, Ting Wang |
| 40 | + |
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