diff --git a/.github/scripts/package.json b/.github/scripts/package.json
index 2c2e5207d..84b201023 100644
--- a/.github/scripts/package.json
+++ b/.github/scripts/package.json
@@ -14,8 +14,8 @@
         "js-yaml": "^4.1.0"
     },
     "devDependencies": {
-        "@octokit/rest": "^19.0.0",
+        "@octokit/rest": "^21.0.0",
         "mocha": "^10.0.0",
-        "sinon": "^18.0.0"
+        "sinon": "^21.0.0"
     }
 }
\ No newline at end of file
diff --git a/package.json b/package.json
index 3c10dde3d..c8924485c 100644
--- a/package.json
+++ b/package.json
@@ -54,15 +54,15 @@
     "@google-cloud/promisify": "^5.0.0",
     "@opentelemetry/api": "~1.9.0",
     "@opentelemetry/core": "^1.30.1",
-    "@opentelemetry/semantic-conventions": "~1.34.0",
-    "arrify": "^2.0.0",
+    "@opentelemetry/semantic-conventions": "~1.38.0",
+    "arrify": "^3.0.0",
     "extend": "^3.0.2",
     "google-auth-library": "^10.5.0",
     "google-gax": "^5.0.5",
     "heap-js": "^2.6.0",
     "is-stream-ended": "^0.1.4",
     "lodash.snakecase": "^4.1.1",
-    "p-defer": "^3.0.0"
+    "p-defer": "^4.0.0"
   },
   "devDependencies": {
     "@grpc/proto-loader": "^0.8.0",
@@ -73,19 +73,19 @@
     "@types/mocha": "^10.0.10",
     "@types/mv": "^2.1.4",
     "@types/ncp": "^2.0.8",
-    "@types/node": "^22.14.1",
+    "@types/node": "^24.0.0",
     "@types/proxyquire": "^1.3.31",
-    "@types/sinon": "^17.0.4",
+    "@types/sinon": "^21.0.0",
     "@types/tmp": "^0.2.6",
-    "@types/uuid": "^10.0.0",
+    "@types/uuid": "^11.0.0",
     "c8": "^10.1.3",
     "codecov": "^3.8.3",
-    "execa": "~5.1.0",
+    "execa": "~9.1.0",
     "gapic-tools": "^1.0.1",
-    "gts": "^6.0.2",
+    "gts": "^7.0.0",
     "jsdoc": "^4.0.4",
-    "jsdoc-fresh": "^4.0.0",
-    "jsdoc-region-tag": "^3.0.0",
+    "jsdoc-fresh": "^5.0.0",
+    "jsdoc-region-tag": "^4.0.0",
     "linkinator": "^6.1.2",
     "mocha": "^11.1.0",
     "mv": "^2.1.1",
@@ -93,13 +93,13 @@
     "nise": "^6.1.1",
     "null-loader": "^4.0.1",
     "path-to-regexp": "^8.2.0",
-    "protobufjs": "^7.4.0",
+    "protobufjs": "^8.0.0",
     "proxyquire": "^2.1.3",
-    "sinon": "^20.0.0",
+    "sinon": "^21.0.0",
     "tmp": "^0.2.3",
     "ts-loader": "^9.5.2",
     "typescript": "^5.8.3",
-    "uuid": "^11.1.0",
+    "uuid": "^13.0.0",
     "webpack": "^5.99.5",
     "webpack-cli": "^6.0.1",
     "why-is-node-running": "^2.3.0",
diff --git a/samples/package.json b/samples/package.json
index 476f6edd0..a9a74c79d 100644
--- a/samples/package.json
+++ b/samples/package.json
@@ -24,7 +24,7 @@
     "posttypeless": "npx eslint --fix *.js"
   },
   "dependencies": {
-    "@google-cloud/opentelemetry-cloud-trace-exporter": "^2.0.0",
+    "@google-cloud/opentelemetry-cloud-trace-exporter": "^3.0.0",
     "@google-cloud/pubsub": "^5.2.1",
     "@google-cloud/storage": "^7.11.1",
     "@opentelemetry/api": "^1.6.0",
@@ -34,19 +34,19 @@
     "@opentelemetry/semantic-conventions": "^1.17.0",
     "avro-js": "^1.11.3",
     "google-auth-library": "^10.5.0",
-    "p-defer": "^3.0.0",
-    "protobufjs": "~7.5.0"
+    "p-defer": "^4.0.0",
+    "protobufjs": "~8.0.0"
   },
   "devDependencies": {
     "@google-cloud/bigquery": "^8.0.0",
     "@google-cloud/typeless-sample-bot": "^3.0.0",
-    "@types/chai": "^4.2.16",
-    "chai": "^4.2.0",
-    "gts": "^6.0.0",
-    "lru-cache": "9.1.2",
-    "mocha": "^9.2.2",
-    "rimraf": "5.0.9",
+    "@types/chai": "^5.0.0",
+    "chai": "^6.0.0",
+    "gts": "^7.0.0",
+    "lru-cache": "10.4.3",
+    "mocha": "^10.0.0",
+    "rimraf": "5.0.10",
     "typescript": "^5.1.6",
-    "uuid": "^9.0.0"
+    "uuid": "^13.0.0"
   }
 }
diff --git a/system-test/fixtures/sample/package.json b/system-test/fixtures/sample/package.json
index 0387c63b4..fa3e4f326 100644
--- a/system-test/fixtures/sample/package.json
+++ b/system-test/fixtures/sample/package.json
@@ -16,8 +16,8 @@
     "@google-cloud/pubsub": "file:./pubsub.tgz"
   },
   "devDependencies": {
-    "@types/node": "^22.0.0",
+    "@types/node": "^24.0.0",
     "typescript": "^5.1.6",
-    "gts": "^6.0.0"
+    "gts": "^7.0.0"
   }
 }