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@susannasiebert susannasiebert commented Oct 15, 2025

  • Fix missing --transcript-prioritization-strategy argument in standalone pvacsplice generate_aggregated_report command
  • Require metrics file in standalone pvacseq update_tiers command so that it can be updated with newly selected tiering parameters
  • The new TranscriptFilter was not being used in the PostProcessor. Instead it was still using the old filtering on the TSL-only
  • Use correct default value for --expn-val parameter in UpdateTiers depending on base tool used
  • Refine transcript prioritization logic to prioritize MANE select or canonical transcripts
  • Include mane select, canonical, and cds flag information in pVACview transcript table

…ne pvacsplice generate_aggregated_report command
…it can be updated with newly selected tiering parameters
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