From 3e41430bb78e655c1e3615e1cbeb5105c801e5fc Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Wed, 15 Oct 2025 15:28:09 -0500 Subject: [PATCH 01/11] Fix missing --transcript-prioritization-strategy argument in standalone pvacsplice generate_aggregated_report command --- .../tools/pvacsplice/generate_aggregated_report.py | 10 ++++++++++ 1 file changed, 10 insertions(+) diff --git a/pvactools/tools/pvacsplice/generate_aggregated_report.py b/pvactools/tools/pvacsplice/generate_aggregated_report.py index 891480998..8c2504d44 100644 --- a/pvactools/tools/pvacsplice/generate_aggregated_report.py +++ b/pvactools/tools/pvacsplice/generate_aggregated_report.py @@ -85,6 +85,15 @@ def define_parser(): default=1.0, help="Gene and Expression cutoff. Used to calculate the allele expression cutoff for tiering.", ) + parser.add_argument( + "--transcript-prioritization-strategy", type=transcript_prioritization_strategy(), + help="Specify the criteria to consider when prioritizing or filtering transcripts of the neoantigen candidates during aggregate report creation or TSL filtering. " + + "'canonical' will prioritize/select candidates resulting from variants on a Ensembl canonical transcript. " + + "'mane_select' will prioritize/select candidates resulting from variants on a MANE select transcript. " + + "'tsl' will prioritize/select candidates where the transcript support level (TSL) matches the --maximum-transcript-support-level. " + + "When selecting more than one criteria, a transcript meeting EITHER of the selected criteria will be prioritized/selected.", + default=['canonical', 'mane_select', 'tsl'] + ) parser.add_argument( "--maximum-transcript-support-level", type=int, help="The threshold to use for filtering epitopes on the Ensembl transcript support level (TSL). " @@ -114,6 +123,7 @@ def main(args_input = sys.argv[1:]): trna_vaf=args.trna_vaf, trna_cov=args.trna_cov, expn_val=args.expn_val, + transcript_prioritization_strategy=args.transcript_prioritization_strategy, maximum_transcript_support_level=args.maximum_transcript_support_level, top_score_metric=args.top_score_metric, top_score_metric2=args.top_score_metric2, From eadfe66daf6040989d02b5760a1e5ebf3d2f8fe9 Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Fri, 17 Oct 2025 08:13:07 -0500 Subject: [PATCH 02/11] Require metrics file in standalone pvacseq update_tiers step so that it can be updated with newly selected tiering parameters --- pvactools/lib/update_tiers.py | 34 + pvactools/tools/pvacseq/update_tiers.py | 1 + ...C1395.all_epitopes.aggregated.metrics.json | 416206 +++++++++++++++ ...5.all_epitopes.aggregated.metrics.out.json | 416206 +++++++++++++++ tests/test_pvacseq_update_tiers.py | 3 +- tests/test_update_tiers.py | 11 +- 6 files changed, 832459 insertions(+), 2 deletions(-) create mode 100644 tests/test_data/update_tiers/HCC1395.all_epitopes.aggregated.metrics.json create mode 100644 tests/test_data/update_tiers/HCC1395.all_epitopes.aggregated.metrics.out.json diff --git a/pvactools/lib/update_tiers.py b/pvactools/lib/update_tiers.py index 525aa813f..a0327958e 100644 --- a/pvactools/lib/update_tiers.py +++ b/pvactools/lib/update_tiers.py @@ -6,6 +6,7 @@ import tempfile import shutil import argparse +import json from pvactools.lib.prediction_class import PredictionClass from pvactools.lib.run_utils import is_preferred_transcript, float_range, transcript_prioritization_strategy @@ -33,6 +34,7 @@ def execute(self): output_df.to_csv(self.output_file, sep='\t', na_rep='NA', index=False, float_format='%.3f') shutil.copy(self.output_file.name, self.input_file) self.output_file.close() + self.update_metrics_file() @abstractmethod def get_tier(self, mutation): @@ -42,6 +44,9 @@ def get_tier(self, mutation): def sort_table(self, output_lines): raise Exception("Must implement method in child class") + def update_metrics_file(self): + pass + @classmethod def parser(cls, tool): parser = argparse.ArgumentParser( @@ -53,6 +58,11 @@ def parser(cls, tool): 'input_file', help="Input aggregated file with tiers to update. This file will be overwritten with the output." ) + if tool in ['pvacseq']: + parser.add_argument( + 'metrics_file', + help="metrics.json file corresponding to the input aggregated file. This file will be overwritten to update tiering parameters used by this command." + ) if tool in ['pvacseq', 'pvacsplice']: parser.add_argument( 'vaf_clonal', type=float_range(0.0, 1.0), @@ -167,6 +177,7 @@ def __init__( allele_specific_anchors=False, anchor_contribution_threshold=0.8, top_score_metric2='ic50', + metrics_file=None, ): self.input_file = input_file self.output_file = tempfile.NamedTemporaryFile() @@ -180,6 +191,7 @@ def __init__( self.trna_vaf = trna_vaf self.transcript_prioritization_strategy = transcript_prioritization_strategy self.maximum_transcript_support_level = maximum_transcript_support_level + self.metrics_file=metrics_file if top_score_metric2 == "percentile": self.top_score_mode = "%ile MT" else: @@ -341,6 +353,28 @@ def sort_table(self, output_lines): return df + def update_metrics_file(self): + if self.metrics_file is not None: + output_metrics_file = tempfile.NamedTemporaryFile() + with open(self.metrics_file, 'r') as input_fh, open(output_metrics_file.name, 'w') as output_fh: + metrics = json.loads(input_fh.read()) + metrics['vaf_clonal'] = round(self.vaf_clonal, 3) + metrics['vaf_subclonal'] = round(self.vaf_clonal/2, 3) + metrics['binding_threshold'] = self.binding_threshold + metrics['trna_vaf'] = self.trna_vaf + metrics['trna_cov'] = self.trna_cov + metrics['allele_expr_threshold'] = self.allele_expr_threshold + metrics['transcript_prioritization_strategy'] = sorted(self.transcript_prioritization_strategy) + metrics['maximum_transcript_support_level'] = self.maximum_transcript_support_level + metrics['percentile_threshold'] = self.percentile_threshold + metrics['percentile_threshold_strategy'] = self.percentile_threshold_strategy + metrics['use_allele_specific_binding_thresholds'] = self.use_allele_specific_binding_thresholds + metrics['top_score_metric2'] = 'ic50' if self.top_score_mode == "IC50 MT" else 'percentile' + metrics['allele_specific_anchors'] = self.anchor_calculator.use_allele_specific_anchors + metrics['anchor_contribution_threshold'] = self.anchor_calculator.anchor_contribution_threshold + json.dump(metrics, output_fh, indent=2, separators=(',', ': ')) + shutil.copy(output_metrics_file.name, self.metrics_file) + class PvacfuseUpdateTiers(UpdateTiers, metaclass=ABCMeta): def __init__( self, diff --git a/pvactools/tools/pvacseq/update_tiers.py b/pvactools/tools/pvacseq/update_tiers.py index 312217518..05cfb84bd 100644 --- a/pvactools/tools/pvacseq/update_tiers.py +++ b/pvactools/tools/pvacseq/update_tiers.py @@ -26,6 +26,7 @@ def main(args_input = sys.argv[1:]): allele_specific_anchors=args.allele_specific_anchors, anchor_contribution_threshold=args.anchor_contribution_threshold, top_score_metric2=args.top_score_metric2, + metrics_file=args.metrics_file, ).execute() if __name__ == "__main__": diff --git a/tests/test_data/update_tiers/HCC1395.all_epitopes.aggregated.metrics.json b/tests/test_data/update_tiers/HCC1395.all_epitopes.aggregated.metrics.json new file mode 100644 index 000000000..aba29e0cd --- /dev/null +++ b/tests/test_data/update_tiers/HCC1395.all_epitopes.aggregated.metrics.json @@ -0,0 +1,416206 @@ +{ + "tumor_purity": null, + "vaf_clonal": 0.5, + "vaf_subclonal": 0.25, + "binding_threshold": 500, + "aggregate_inclusion_binding_threshold": 5000, + "aggregate_inclusion_count_limit": 15, + "trna_vaf": 0.25, + "trna_cov": 10, + "allele_expr_threshold": 2.5, + "transcript_prioritization_strategy": [ + "canonical", + "mane_select", + "tsl" + ], + "maximum_transcript_support_level": 1, + "percentile_threshold": null, + "percentile_threshold_strategy": "conservative", + "use_allele_specific_binding_thresholds": false, + "mt_top_score_metric": "Median", + "wt_top_score_metric": "Median", + "top_score_metric2": "ic50", + "allele_specific_binding_thresholds": { + "HLA-A*29:02": 641.0 + }, + "allele_specific_anchors": false, + "alleles": [ + "HLA-A*29:02", + "HLA-B*45:01", + "HLA-B*82:02", + "HLA-C*06:02" + ], + "anchor_contribution_threshold": 0.8, + "epitope_lengths": [ + 8, + 9, + 10, + 11 + ], + "chr1-16006133-16006134-G-T": { + "good_binders": { + "Transcript Set 1": { + "peptides": { + "LTRVTPMGW": { + "ic50s_MT": [ + 16030.830078125, + "X", + "X", + "X" + ], + "percentiles_MT": [ + 17.0, + "X", + "X", + "X" + ], + "ic50s_WT": [ + 32580.285, + "X", + "X", + "X" + ], + "percentiles_WT": [ + 43.0, + "X", + "X", + "X" + ], + "hla_types": [ + "HLA-A*29:02", + "HLA-B*45:01", + "HLA-B*82:02", + "HLA-C*06:02" + ], + "mutation_position": "9", + "problematic_positions": "None", + "anchor_fails": "None", + "individual_ic50_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-A*29:02": [ + 9014.660225886144, + 5981.25, + 18162.85, + 17695.75, + 16395.23, + 6829.04, + 21026.16, + 15666.43 + ] + }, + "WT": { + "HLA-A*29:02": [ + 26225.41063907933, + 6005.84, + 32147.95, + 33144.32, + 33012.62, + 11479.16, + 63791.09, + 39081.39 + ] + } + }, + "individual_ic50_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-A*29:02": [ + 4.7870001792907715, + 89.2699966430664, + 16.0, + 24.0, + 9.5, + 18.0, + 30.0, + 25.0 + ] + }, + "WT": { + "HLA-A*29:02": [ + 21.751124999999995, + 96.42, + 43.0, + 70.0, + 38.0, + 30.0, + 55.0, + 43.0 + ] + } + }, + "individual_el_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-A*29:02": [ + 0.3713827189058065, + 0.0388725626944029, + 0.00531, + 0.002129014, + 0.1501468, + "NA" + ] + }, + "WT": { + "HLA-A*29:02": [ + 0.0080413394316565, + 0.0039477551712865, + 4.4e-05, + 0.0005424515, + 0.03344151, + "NA" + ] + } + }, + "individual_el_percentile_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-A*29:02": [ + "NA", + 6.479157608695644, + 4.3, + "NA", + "NA", + "NA" + ] + }, + "WT": { + "HLA-A*29:02": [ + "NA", + 99.28660326086955, + 37.0, + "NA", + "NA", + "NA" + ] + } + }, + "individual_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC", + "MHCflurryEL Presentation", + "NetMHCpanEL" + ], + "MT": { + "HLA-A*29:02": [ + 4.7870001792907715, + 89.2699966430664, + 16.0, + 24.0, + 9.5, + 18.0, + 30.0, + 25.0, + 6.479157608695644, + 4.3 + ] + }, + "WT": { + "HLA-A*29:02": [ + 21.751124999999995, + 96.42, + 43.0, + 70.0, + 38.0, + 30.0, + 55.0, + 43.0, + 99.28660326086955, + 37.0 + ] + } + }, + "wt_peptide": "LTRVTPMGG" + }, + "TPMGWGCL": { + "ic50s_MT": [ + "X", + "X", + 508.8699951171875, + "X" + ], + "percentiles_MT": [ + "X", + "X", + 0.6000000238418579, + "X" + ], + "ic50s_WT": [ + "X", + "X", + 560.92, + "X" + ], + "percentiles_WT": [ + "X", + "X", + 0.45, + "X" + ], + "hla_types": [ + "HLA-A*29:02", + "HLA-B*45:01", + "HLA-B*82:02", + "HLA-C*06:02" + ], + "mutation_position": "5", + "problematic_positions": "7", + "anchor_fails": "None", + "individual_ic50_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-B*82:02": [ + 17232.073336914338, + 88.84, + "NA", + 412.08, + 3189.11, + 508.87, + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + 5083.2097698078605, + 121.73, + "NA", + 528.51, + 3445.28, + 560.92, + "NA", + "NA" + ] + } + }, + "individual_ic50_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-B*82:02": [ + 3.1801249980926514, + 0.3199999928474426, + "NA", + 0.11999999731779099, + 0.33000001311302185, + 0.6000000238418579, + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + 0.7691249999999993, + 0.4499999999999999, + "NA", + 0.19, + 0.36, + 0.7, + "NA", + "NA" + ] + } + }, + "individual_el_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-B*82:02": [ + 0.1149642604868859, + 0.0086250725040742, + 0.0889, + 0.0008980603, + 0.0074019865, + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + 0.2750012096948921, + 0.047773523095293, + 0.162, + 0.0016809524, + 0.007587356, + "NA" + ] + } + }, + "individual_el_percentile_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-B*82:02": [ + "NA", + 27.61739130434782, + 1.0, + "NA", + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + "NA", + 5.346684782608634, + 0.43, + "NA", + "NA", + "NA" + ] + } + }, + "individual_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC", + "MHCflurryEL Presentation", + "NetMHCpanEL" + ], + "MT": { + "HLA-B*82:02": [ + 3.1801249980926514, + 0.3199999928474426, + "NA", + 0.11999999731779099, + 0.33000001311302185, + 0.6000000238418579, + "NA", + "NA", + 27.61739130434782, + 1.0 + ] + }, + "WT": { + "HLA-B*82:02": [ + 0.7691249999999993, + 0.4499999999999999, + "NA", + 0.19, + 0.36, + 0.7, + "NA", + "NA", + 5.346684782608634, + 0.43 + ] + } + }, + "wt_peptide": "TPMGGGCL" + }, + "TPMGWGCLA": { + "ic50s_MT": [ + "X", + "X", + 696.4299926757812, + "X" + ], + "percentiles_MT": [ + "X", + "X", + 0.8299999833106995, + "X" + ], + "ic50s_WT": [ + "X", + "X", + 631.81, + "X" + ], + "percentiles_WT": [ + "X", + "X", + 0.53, + "X" + ], + "hla_types": [ + "HLA-A*29:02", + "HLA-B*45:01", + "HLA-B*82:02", + "HLA-C*06:02" + ], + "mutation_position": "5", + "problematic_positions": "7", + "anchor_fails": "None", + "individual_ic50_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-B*82:02": [ + 1293.515799420945, + 243.56, + "NA", + 696.43, + 1338.42, + 548.91, + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + 349.2484436729933, + 149.28, + "NA", + 917.7, + 1273.93, + 631.81, + "NA", + "NA" + ] + } + }, + "individual_ic50_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-B*82:02": [ + 0.3008750081062317, + 0.8299999833106995, + "NA", + 0.6000000238418579, + 0.10999999940395355, + 1.899999976158142, + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + 0.088, + 0.53, + "NA", + 0.9, + 0.1, + 2.3, + "NA", + "NA" + ] + } + }, + "individual_el_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-B*82:02": [ + 0.1391799231059849, + 0.1049391539873417, + 0.0991, + 0.0014974733, + 0.0075100204, + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + 0.2387542352080345, + 0.3729979814349322, + 0.173, + 0.0035871782, + 0.009139342, + "NA" + ] + } + }, + "individual_el_percentile_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-B*82:02": [ + "NA", + 2.832907608695578, + 0.88, + "NA", + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + "NA", + 1.1307065217390004, + 0.4, + "NA", + "NA", + "NA" + ] + } + }, + "individual_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC", + "MHCflurryEL Presentation", + "NetMHCpanEL" + ], + "MT": { + "HLA-B*82:02": [ + 0.3008750081062317, + 0.8299999833106995, + "NA", + 0.6000000238418579, + 0.10999999940395355, + 1.899999976158142, + "NA", + "NA", + 2.832907608695578, + 0.88 + ] + }, + "WT": { + "HLA-B*82:02": [ + 0.088, + 0.53, + "NA", + 0.9, + 0.1, + 2.3, + "NA", + "NA", + 1.1307065217390004, + 0.4 + ] + } + }, + "wt_peptide": "TPMGGGCLA" + }, + "TPMGWGCLAQA": { + "ic50s_MT": [ + "X", + "X", + 1006.0999755859375, + "X" + ], + "percentiles_MT": [ + "X", + "X", + 1.2000000476837158, + "X" + ], + "ic50s_WT": [ + "X", + "X", + 1039.29, + "X" + ], + "percentiles_WT": [ + "X", + "X", + 0.59, + "X" + ], + "hla_types": [ + "HLA-A*29:02", + "HLA-B*45:01", + "HLA-B*82:02", + "HLA-C*06:02" + ], + "mutation_position": "5", + "problematic_positions": "7", + "anchor_fails": "None", + "individual_ic50_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + 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"DeepImmuno" + ], + "MT": { + "HLA-B*45:01": [ + "NA", + 9.15535326086956, + 1.6, + "NA", + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*45:01": [ + "NA", + 12.187228260869546, + 1.9, + "NA", + "NA", + "NA" + ] + } + }, + "individual_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC", + "MHCflurryEL Presentation", + "NetMHCpanEL" + ], + "MT": { + "HLA-B*45:01": [ + 2.1241250038146973, + 3.890000104904175, + 4.400000095367432, + 3.9000000953674316, + 3.299999952316284, + 5.300000190734863, + 1.0, + 1.1, + 9.15535326086956, + 1.6 + ] + }, + "WT": { + "HLA-B*45:01": [ + 2.358125, + 4.64, + 3.2, + 3.6, + 3.5, + 5.5, + 1.0, + 1.4, + 12.187228260869546, + 1.9 + ] + } + }, + "wt_peptide": "PEELLNDHA" + }, + "LVNDHAREN": { + "ic50s_MT": [ + "X", + "X", + "X", + 4987.5048828125 + ], + "percentiles_MT": [ + "X", + "X", + "X", + 13.57800006866455 + ], + "ic50s_WT": [ + "X", + "X", + "X", + 6824.285 + 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}, + "WT": { + "HLA-C*06:02": [ + 16.155625000000004, + 18.360000000000003, + 1.5, + 15.0, + 26.0, + 12.0, + 3.4, + 2.5 + ] + } + }, + "individual_el_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-C*06:02": [ + 0.002992731067934, + 0.0104628811352932, + 0.000184, + 0.0020946837, + 0.07948076, + 0.9544299 + ] + }, + "WT": { + "HLA-C*06:02": [ + 0.0045024009523331, + 0.0091441515328275, + 7.4e-05, + 0.0011414761, + 0.03940774, + 0.9567649 + ] + } + }, + "individual_el_percentile_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-C*06:02": [ + "NA", + 22.19230978260869, + 19.0, + "NA", + "NA", + "NA" + ] + }, + "WT": { + "HLA-C*06:02": [ + "NA", + 24.57923913043477, + 26.0, + "NA", + "NA", + "NA" + ] + } + }, + "individual_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC", + "MHCflurryEL Presentation", + "NetMHCpanEL" + ], + "MT": { + "HLA-C*06:02": [ + 14.156000137329102, + 14.880000114440918, + 0.9399999976158142, + 13.0, + 22.0, + 4.599999904632568, + 1.3, + 0.9, + 22.19230978260869, + 19.0 + ] + }, + "WT": { + "HLA-C*06:02": [ + 16.155625000000004, + 18.360000000000003, + 1.5, + 15.0, + 26.0, + 12.0, + 3.4, + 2.5, + 24.57923913043477, + 26.0 + ] + } + }, + "wt_peptide": "LLNDHAREN" + } + }, + "transcripts": [ + "ENST00000449283.2-SPANXB1-L/V-74" + ], + "transcript_expr": [ + 0.0 + ], + "mane_select": [ + true + ], + "canonical": [ + true + ], + "tsl": [ + 1 + ], + "biotype": [ + "protein_coding" + ], + "transcript_cds_flags": [ + "None" + ], + "transcript_length": [ + 103 + ], + "transcript_count": 1, + "peptide_count": 3, + "total_expr": 0.0 + } + }, + "sets": [ + "Transcript Set 1" + ], + "transcript_counts": [ + 1 + ], 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10246.39, + 22684.98, + 9972.95, + 13447.14, + 3538.91 + ] + }, + "WT": { + "HLA-A*29:02": [ + 31382.177204102543, + 5888.44, + 34090.69, + 34423.54, + 37081.02, + 29745.37, + 13447.14, + 4244.92 + ] + } + }, + "individual_ic50_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-A*29:02": [ + 12.845624923706055, + 5.800000190734863, + 28.0, + 9.0, + 17.0, + 8.800000190734863, + 42.0, + 9.8 + ] + }, + "WT": { + "HLA-A*29:02": [ + 50.764875, + 39.69, + 50.0, + 67.0, + 53.0, + 32.0, + 42.0, + 13.0 + ] + } + }, + "individual_el_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-A*29:02": [ + 0.1322458796203136, + 0.0074586783774095, + 0.00172, + 0.001694218, + 0.04995152, + "NA" + ] + }, + "WT": { + "HLA-A*29:02": [ + 0.002622721120133, + 0.00325535502289, + 6e-06, + 0.0013578403, + 0.050127428, + "NA" + ] + } + }, + "individual_el_percentile_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-A*29:02": [ + "NA", + 31.64317934782608, + 7.4, + "NA", + "NA", + "NA" + ] + }, + "WT": { + "HLA-A*29:02": [ + "NA", + 99.28660326086955, + 68.0, + "NA", + "NA", + "NA" + ] + } + }, + "individual_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC", + "MHCflurryEL Presentation", + "NetMHCpanEL" + ], + "MT": { + "HLA-A*29:02": [ + 12.845624923706055, + 5.800000190734863, + 28.0, + 9.0, + 17.0, + 8.800000190734863, + 42.0, + 9.8, + 31.64317934782608, + 7.4 + ] + }, + "WT": { + "HLA-A*29:02": [ + 50.764875, + 39.69, + 50.0, + 67.0, + 53.0, + 32.0, + 42.0, + 13.0, + 99.28660326086955, + 68.0 + ] + } + }, + "wt_peptide": "YVGQKSSFTVD" + } + }, + "transcripts": [ + "ENST00000369850.10-FLNA-D/H-2581" + ], + "transcript_expr": [ + 21.322 + ], + "mane_select": [ + true + ], + "canonical": [ + true + ], + "tsl": [ + 1 + ], + "biotype": [ + "protein_coding" + ], + "transcript_cds_flags": [ + "None" + ], + "transcript_length": [ + 2647 + ], + "transcript_count": 1, + "peptide_count": 1, + "total_expr": 21.322 + } + }, + "sets": [ + "Transcript Set 1" + ], + "transcript_counts": [ + 1 + ], + "peptide_counts": [ + 1 + ], + "set_expr": [ + 21.322 + ], + "DNA VAF": 0.992, + "RNA VAF": 0.998, + "gene_expr": 706.463, + "best_peptide_mt": "YVGQKSSFTVH", + "best_peptide_wt": "YVGQKSSFTVD", + "best_hla_allele": "HLA-A*29:02" + } +} \ No newline at end of file diff --git a/tests/test_pvacseq_update_tiers.py b/tests/test_pvacseq_update_tiers.py index fb6f3ae47..8cc51a762 100644 --- a/tests/test_pvacseq_update_tiers.py +++ b/tests/test_pvacseq_update_tiers.py @@ -53,4 +53,5 @@ def test_compiles(self): def test_runs(self): input_file = os.path.join(self.test_data_directory, 'MHC_Class_I', 'Test.MHC_I.all_epitopes.aggregated.tsv') - self.assertFalse(update_tiers.main([input_file, "0.5"])) + input_metrics_file = os.path.join(self.test_data_directory, 'MHC_Class_I', 'Test.MHC_I.all_epitopes.aggregated.metrics.json') + self.assertFalse(update_tiers.main([input_file, input_metrics_file, "0.5"])) diff --git a/tests/test_update_tiers.py b/tests/test_update_tiers.py index b11dbba8f..3003d325c 100644 --- a/tests/test_update_tiers.py +++ b/tests/test_update_tiers.py @@ -25,15 +25,24 @@ def test_update_tiers_pvacseq(self): input_file = os.path.join(self.test_data_dir, 'HCC1395.all_epitopes.aggregated.tsv') tmp_input_file = tempfile.NamedTemporaryFile() shutil.copy(input_file, tmp_input_file.name) + input_metrics_file = os.path.join(self.test_data_dir, 'HCC1395.all_epitopes.aggregated.metrics.json') + tmp_input_metrics_file = tempfile.NamedTemporaryFile() + shutil.copy(input_metrics_file, tmp_input_metrics_file.name) self.assertFalse(PvacseqUpdateTiers( tmp_input_file.name, - 0.5 + 0.5, + metrics_file=tmp_input_metrics_file.name ).execute()) self.assertTrue(cmp( tmp_input_file.name, os.path.join(self.test_data_dir, "HCC1395.all_epitopes.aggregated.out.tsv"), )) + self.assertTrue(cmp( + tmp_input_metrics_file.name, + os.path.join(self.test_data_dir, "HCC1395.all_epitopes.aggregated.metrics.out.json"), + )) tmp_input_file.close() + tmp_input_metrics_file.close() def test_update_tiers_pvacsplice(self): input_file = os.path.join(self.test_data_dir, 'HCC1395.pvacsplice.all_epitopes.aggregated.tsv') From d301202f09ed5a82b9122f2f9c80841a08a40f13 Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Mon, 20 Oct 2025 09:11:48 -0500 Subject: [PATCH 03/11] Use TranscriptFilter in PostProcessor --- pvactools/lib/post_processor.py | 8 ++++---- .../MHC_Class_II/HCC1395_TUMOR_DNA.MHC_II.filtered.tsv | 2 ++ .../run_combined/HCC1395_TUMOR_DNA.Combined.filtered.tsv | 2 ++ 3 files changed, 8 insertions(+), 4 deletions(-) diff --git a/pvactools/lib/post_processor.py b/pvactools/lib/post_processor.py index fd9e24e66..4f88d4fad 100644 --- a/pvactools/lib/post_processor.py +++ b/pvactools/lib/post_processor.py @@ -6,6 +6,7 @@ from pvactools.lib.aggregate_all_epitopes import PvacseqAggregateAllEpitopes, PvacfuseAggregateAllEpitopes, PvacbindAggregateAllEpitopes, PvacspliceAggregateAllEpitopes from pvactools.lib.binding_filter import BindingFilter from pvactools.lib.filter import Filter, FilterCriterion +from pvactools.lib.transcript_filter import TranscriptFilter from pvactools.lib.top_score_filter import PvacseqTopScoreFilter, PvacfuseTopScoreFilter, PvacbindTopScoreFilter, PvacspliceTopScoreFilter from pvactools.lib.calculate_manufacturability import CalculateManufacturability from pvactools.lib.calculate_reference_proteome_similarity import CalculateReferenceProteomeSimilarity @@ -225,12 +226,11 @@ def execute_coverage_filter(self): def execute_transcript_support_level_filter(self): if self.run_transcript_support_level_filter: print("Running Transcript Support Level Filter") - filter_criteria = [FilterCriterion('Transcript Support Level', '<=', self.maximum_transcript_support_level, exclude_nas=True, skip_value='Not Supported')] - Filter( + TranscriptFilter( self.coverage_filter_fh.name, self.transcript_support_level_filter_fh.name, - filter_criteria, - ['Transcript Support Level'], + self.transcript_prioritization_strategy, + self.maximum_transcript_support_level ).execute() print("Complete") else: diff --git a/tests/test_data/pvacsplice/results/run/MHC_Class_II/HCC1395_TUMOR_DNA.MHC_II.filtered.tsv b/tests/test_data/pvacsplice/results/run/MHC_Class_II/HCC1395_TUMOR_DNA.MHC_II.filtered.tsv index bb61d0ec7..b1b9556ba 100644 --- a/tests/test_data/pvacsplice/results/run/MHC_Class_II/HCC1395_TUMOR_DNA.MHC_II.filtered.tsv +++ b/tests/test_data/pvacsplice/results/run/MHC_Class_II/HCC1395_TUMOR_DNA.MHC_II.filtered.tsv @@ -1,6 +1,8 @@ Chromosome Start Stop Reference Variant Junction Junction Start Junction Stop Junction Score Junction Anchor Transcript Transcript Support Level Canonical MANE Select Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Amino Acid Change Gene Name HGVSc HGVSp WT Protein Length ALT Protein Length Frameshift Event Protein Position HLA Allele Peptide Length Epitope Seq Median IC50 Score Best IC50 Score Best IC50 Score Method Median Percentile Best Percentile Best Percentile Method Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Index Fasta Key NNalign IC50 Score NNalign Percentile Problematic Positions Gene of Interest cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 751 HLA-DRB1*11:01 15 KEKFEKQLKKKSEEK 31.7 31.7 NNalign 3.2 3.2 NNalign 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 31.7 3.2 None False -3.3428571428571425 -1.671428571428572 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 751 HLA-DRB1*11:01 15 KEKFEKQLKKKSEEK 31.7 31.7 NNalign 3.2 3.2 NNalign 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 31.7 3.2 None False -3.3428571428571425 -1.671428571428572 False False False 0 False 0 chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-DRB1*11:01 15 KVYCLQKELKIKNHS 142.9 142.9 NNalign 12.0 12.0 NNalign 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 13 142.9 12.0 4 False -0.9999999999999999 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-DRB1*11:01 15 KVYCLQKELKIKNHS 142.9 142.9 NNalign 12.0 12.0 NNalign 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 13 142.9 12.0 4 False -0.9999999999999999 -0.24285714285714294 False False False 1 False 0 chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 26 HLA-DRB1*11:01 15 HIMKSADVVKQRFKN 742.4 742.4 NNalign 30.0 30.0 NNalign 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 43 742.4 30.0 None False -1.757142857142857 0.6000000000000002 False False False 0 False 0 chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 26 HLA-DRB1*11:01 15 HIMKSADVVKQRFKN 742.4 742.4 NNalign 30.0 30.0 NNalign 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 43 742.4 30.0 None False -1.757142857142857 0.6000000000000002 False False False 0 False 0 chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 23 HLA-DRB1*11:01 15 SKTHIMKSADVVKVK 1076.4 1076.4 NNalign 36.0 36.0 NNalign 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 29 1076.4 36.0 None False 0.4428571428571429 0.8857142857142859 False False False 0 False 0 diff --git a/tests/test_data/pvacsplice/results/run_combined/HCC1395_TUMOR_DNA.Combined.filtered.tsv b/tests/test_data/pvacsplice/results/run_combined/HCC1395_TUMOR_DNA.Combined.filtered.tsv index 0bc26501d..6f3ef899f 100644 --- a/tests/test_data/pvacsplice/results/run_combined/HCC1395_TUMOR_DNA.Combined.filtered.tsv +++ b/tests/test_data/pvacsplice/results/run_combined/HCC1395_TUMOR_DNA.Combined.filtered.tsv @@ -1,6 +1,8 @@ Chromosome Start Stop Reference Variant Junction Junction Start Junction Stop Junction Score Junction Anchor Transcript Transcript Support Level Canonical MANE Select Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Amino Acid Change Gene Name HGVSc HGVSp WT Protein Length ALT Protein Length Frameshift Event Protein Position HLA Allele Peptide Length Epitope Seq Median IC50 Score Best IC50 Score Best IC50 Score Method Median Percentile Best Percentile Best Percentile Method Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Index Fasta Key NetMHC IC50 Score NetMHC Percentile PickPocket IC50 Score PickPocket Percentile Gene of Interest cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count NNalign IC50 Score NNalign Percentile chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 751 HLA-DRB1*11:01 15 KEKFEKQLKKKSEEK 31.7 31.7 NNalign 3.2 3.2 NNalign 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA NA NA False -3.3428571428571425 -1.671428571428572 False False False 0 False 0 31.7 3.2 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 751 HLA-DRB1*11:01 15 KEKFEKQLKKKSEEK 31.7 31.7 NNalign 3.2 3.2 NNalign 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA NA NA False -3.3428571428571425 -1.671428571428572 False False False 0 False 0 31.7 3.2 chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-DRB1*11:01 15 KVYCLQKELKIKNHS 142.9 142.9 NNalign 12.0 12.0 NNalign 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 13 NA NA NA NA False -0.9999999999999999 -0.24285714285714294 False False False 1 False 0 142.9 12.0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-DRB1*11:01 15 KVYCLQKELKIKNHS 142.9 142.9 NNalign 12.0 12.0 NNalign 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 13 NA NA NA NA False -0.9999999999999999 -0.24285714285714294 False False False 1 False 0 142.9 12.0 chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 30 HLA-DRB1*11:01 15 SADVVKVKCKLTQSF 278.2 278.2 NNalign 18.0 18.0 NNalign 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 36 NA NA NA NA False 0.028571428571428532 0.8857142857142859 False False False 1 False 0 278.2 18.0 chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 30 HLA-DRB1*11:01 15 SADVVKVKCKLTQSF 278.2 278.2 NNalign 18.0 18.0 NNalign 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 36 NA NA NA NA False 0.028571428571428532 0.8857142857142859 False False False 1 False 0 278.2 18.0 chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 26 HLA-DRB1*11:01 15 HIMKSADVVKQRFKN 742.4 742.4 NNalign 30.0 30.0 NNalign 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 43 NA NA NA NA False -1.757142857142857 0.6000000000000002 False False False 0 False 0 742.4 30.0 From b349b3e48f322678c3edb26cf2be468a41f8bf3f Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Mon, 20 Oct 2025 12:46:56 -0500 Subject: [PATCH 04/11] Use correct default value for --expn-val in UpdateTiers depending on base tool --- pvactools/lib/update_tiers.py | 8 +++++++- 1 file changed, 7 insertions(+), 1 deletion(-) diff --git a/pvactools/lib/update_tiers.py b/pvactools/lib/update_tiers.py index a0327958e..bf662c4dc 100644 --- a/pvactools/lib/update_tiers.py +++ b/pvactools/lib/update_tiers.py @@ -109,7 +109,13 @@ def parser(cls, tool): help="Tumor RNA Coverage Cutoff to consider when evaluating the expression criteria. Only sites above this read depth cutoff will be considered.", default=10 ) - if tool in ['pvacseq', 'pvacfuse', 'pvacsplice']: + if tool in ['pvacseq', 'pvacsplice']: + parser.add_argument( + '--expn-val', type=float, + help="Gene and Transcript Expression cutoff. Sites above this cutoff will be considered.", + default=1.0 + ) + if tool in ['pvacfuse']: parser.add_argument( '--expn-val', type=float, help="Expression Cutoff to consider when evaluating the expression criteria. Expression is meassured as FFPM (fusion fragments per million total reads). Sites above this cutoff will be considered.", From 2ab97e32e55c3887e520a6f271c1df95bf4783a8 Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Wed, 22 Oct 2025 08:50:59 -0500 Subject: [PATCH 05/11] Refine transcript prioritiziation logic to prioritize mane select or canonical transcripts --- pvactools/lib/aggregate_all_epitopes.py | 30 +- pvactools/lib/get_best_candidate.py | 118 +- .../HCC1395.output.metrics.json | 6913 ++++++----------- .../aggregate_all_epitopes/HCC1395.output.tsv | 44 +- tests/test_data/top_score_filter/input.tsv | 2012 ++--- .../top_score_filter/input_pvacsplice.tsv | 898 +-- .../top_score_filter/output_HCC1395.tsv | 18 +- .../top_score_filter/output_lowest.tsv | 48 +- .../top_score_filter/output_median.tsv | 48 +- .../top_score_filter/output_pvacsplice.tsv | 30 +- .../output_pvacsplice_percentile.tsv | 30 +- 11 files changed, 3778 insertions(+), 6411 deletions(-) diff --git a/pvactools/lib/aggregate_all_epitopes.py b/pvactools/lib/aggregate_all_epitopes.py index ea038f9d1..ae09f3078 100644 --- a/pvactools/lib/aggregate_all_epitopes.py +++ b/pvactools/lib/aggregate_all_epitopes.py @@ -598,17 +598,31 @@ def sort_transcripts(self, annotations, included_df): transcript_table = pd.DataFrame.from_records(records) transcript_table['Biotype Sort'] = transcript_table.Biotype.map(lambda x: 1 if x == 'protein_coding' else 2) - transcript_table['TSL Sort'] = transcript_table.apply(lambda x: 1 if is_preferred_transcript(x, self.transcript_prioritization_strategy, self.maximum_transcript_support_level) else 2, axis=1) - + transcript_table['mane_select_sort'] = transcript_table["MANE Select"].apply(lambda x: 1 if x else 2) + transcript_table['canonical_sort'] = transcript_table["Canonical"].apply(lambda x: 1 if x else 2) + transcript_table['tsl_sort'] = transcript_table["Transcript Support Level"].apply(lambda x: 6 if x in ['NA', 'Not Supported'] or pd.isna(x) else int(x)) + sort_columns = [ + "Biotype Sort", + "mane_select_sort", + "canonical_sort", + "tsl_sort", + "Length", + "Expr" + ] + sort_orders = [ + True, + True, + True, + True, + False, + False + ] if self.allow_incomplete_transcripts: transcript_table['Transcript CDS Flags Sort'] = transcript_table['Transcript CDS Flags'].apply(lambda x: 1 if x == "None" else (2 if any(flag in str(x) for flag in ["cds_start_nf", "cds_end_nf"]) else 1)) - sort_columns = ["Biotype Sort", "Transcript CDS Flags Sort", "TSL Sort", "Length"] - sort_order = [True, True, True, False] - else: - sort_columns = ["Biotype Sort", "TSL Sort", "Length"] - sort_order = [True, True, False] + sort_columns.insert(0, 'Transcript CDS Flags Sort') + sort_orders.insert(0, True) - transcript_table.sort_values(by=sort_columns, ascending=sort_order, inplace=True) + transcript_table.sort_values(by=sort_columns, ascending=sort_orders, inplace=True) return transcript_table def calculate_unique_peptide_count(self, included_df): diff --git a/pvactools/lib/get_best_candidate.py b/pvactools/lib/get_best_candidate.py index 23c306c21..d9c71e29d 100644 --- a/pvactools/lib/get_best_candidate.py +++ b/pvactools/lib/get_best_candidate.py @@ -1,3 +1,5 @@ +import pandas as pd + from pvactools.lib.anchor_residue_pass import AnchorResiduePass from pvactools.lib.run_utils import is_preferred_transcript @@ -19,11 +21,19 @@ def __init__( self.allow_incomplete_transcripts = allow_incomplete_transcripts def get(self, df): - #get all entries with Biotype 'protein_coding' - biotype_df = df[df['Biotype'] == 'protein_coding'] + #get all entries that don't have CDS Flags + if self.allow_incomplete_transcripts: + cds_df = df[df['Transcript CDS Flags'] == 'None'] + if cds_df.shape[0] == 0: + cds_df = df + else: + cds_df = df + + #subset cds dataframe to only get entries with Biotype 'protein_coding' + biotype_df = cds_df[cds_df['Biotype'] == 'protein_coding'] #if there are none, reset to previous dataframe if biotype_df.shape[0] == 0: - biotype_df = df + biotype_df = cds_df #subset protein_coding dataframe to only preferred transcripts biotype_df['transcript_pass'] = biotype_df.apply(lambda x: is_preferred_transcript(x, self.transcript_prioritization_strategy, self.maximum_transcript_support_level), axis=1) @@ -32,7 +42,7 @@ def get(self, df): if transcript_df.shape[0] == 0: transcript_df = biotype_df - #subset tsl dataframe to only include entries with no problematic positions + #subset transcript dataframe to only include entries with no problematic positions if 'Problematic Positions' in transcript_df: prob_pos_df = transcript_df[transcript_df['Problematic Positions'] == "None"] #if this results in an empty dataframe, reset to previous dataframe @@ -47,28 +57,31 @@ def get(self, df): if anchor_residue_pass_df.shape[0] == 0: anchor_residue_pass_df = prob_pos_df - # if allow_incomplete_transcripts is True, deprioritize certain flags - if self.allow_incomplete_transcripts: - anchor_residue_pass_df['Transcript CDS Flags Sort'] = anchor_residue_pass_df['Transcript CDS Flags'].apply( - lambda x: 1 if x == "None" else (2 if any(flag in str(x) for flag in ["cds_start_nf", "cds_end_nf"]) else 1) - ) - sort_columns = [ - 'Transcript CDS Flags Sort', - f"{self.mt_top_score_metric} MT {self.top_score_mode}", - 'Transcript Length', - ] - sort_order = [True, True, False] - else: - sort_columns = [ - f"{self.mt_top_score_metric} MT {self.top_score_mode}", - 'Transcript Length', - ] - sort_order = [True, False] - - #determine the entry with the lowest IC50 Score, transcript prioritization status, and longest Transcript + #set up sorting criteria + anchor_residue_pass_df['mane_select_sort'] = anchor_residue_pass_df["MANE Select"].apply(lambda x: 1 if x else 2) + anchor_residue_pass_df['canonical_sort'] = anchor_residue_pass_df["Canonical"].apply(lambda x: 1 if x else 2) + anchor_residue_pass_df['tsl_sort'] = anchor_residue_pass_df["Transcript Support Level"].apply(lambda x: 6 if x in ['NA', 'Not Supported'] or pd.isna(x) else int(x)) + sort_columns = [ + f"{self.mt_top_score_metric} MT {self.top_score_mode}", + "mane_select_sort", + "canonical_sort", + "tsl_sort", + "Transcript Length", + "Transcript Expression" + ] + sort_orders = [ + True, + True, + True, + True, + False, + False + ] + + #Sort the dataframe according to the criteria and pick the first (best) one anchor_residue_pass_df.sort_values( by=sort_columns, - ascending=sort_order, + ascending=sort_orders, inplace=True ) return anchor_residue_pass_df.iloc[0] @@ -127,11 +140,19 @@ def __init__( self.allow_incomplete_transcripts=allow_incomplete_transcripts def get(self, df): - #get all entries with Biotype 'protein_coding' - biotype_df = df[df['Biotype'] == 'protein_coding'] + #get all entries that don't have CDS Flags + if self.allow_incomplete_transcripts: + cds_df = df[df['Transcript CDS Flags'] == 'None'] + if cds_df.shape[0] == 0: + cds_df = df + else: + cds_df = df + + #subset cds dataframe to only get entries with Biotype 'protein_coding' + biotype_df = cds_df[cds_df['Biotype'] == 'protein_coding'] #if there are none, reset to previous dataframe if biotype_df.shape[0] == 0: - biotype_df = df + biotype_df = cds_df #subset protein_coding dataframe to only preferred transcripts biotype_df['transcript_pass'] = biotype_df.apply(lambda x: is_preferred_transcript(x, self.transcript_prioritization_strategy, self.maximum_transcript_support_level), axis=1) @@ -149,28 +170,31 @@ def get(self, df): else: prob_pos_df = transcript_df - # if allow_incomplete_transcripts is True, deprioritize certain flags - if self.allow_incomplete_transcripts: - prob_pos_df['Transcript CDS Flags Sort'] = prob_pos_df['Transcript CDS Flags'].apply( - lambda x: 1 if x == "None" else (2 if any(flag in str(x) for flag in ["cds_start_nf", "cds_end_nf"]) else 1) - ) - sort_columns = [ - 'Transcript CDS Flags Sort', - f"{self.mt_top_score_metric} {self.top_score_mode}", - "WT Protein Length", - ] - sort_order = [True, True, False] - else: - sort_columns = [ - f"{self.mt_top_score_metric} {self.top_score_mode}", - "WT Protein Length", - ] - sort_order = [True, False] - - #determine the entry with the lowest IC50 Score, transcript prioritization status, and longest Transcript + #set up sorting criteria + prob_pos_df['mane_select_sort'] = prob_pos_df["MANE Select"].apply(lambda x: 1 if x else 2) + prob_pos_df['canonical_sort'] = prob_pos_df["Canonical"].apply(lambda x: 1 if x else 2) + prob_pos_df['tsl_sort'] = prob_pos_df["Transcript Support Level"].apply(lambda x: 6 if x in ['NA', 'Not Supported'] or pd.isna(x) else int(x)) + sort_columns = [ + f"{self.mt_top_score_metric} {self.top_score_mode}", + "mane_select_sort", + "canonical_sort", + "tsl_sort", + "WT Protein Length", + "Transcript Expression" + ] + sort_orders = [ + True, + True, + True, + True, + False, + False + ] + + #Sort the dataframe according to the criteria and pick the first (best) one prob_pos_df.sort_values( by=sort_columns, - ascending=sort_order, + ascending=sort_orders, inplace=True ) return prob_pos_df.iloc[0] diff --git a/tests/test_data/aggregate_all_epitopes/HCC1395.output.metrics.json b/tests/test_data/aggregate_all_epitopes/HCC1395.output.metrics.json index aba29e0cd..4dc562356 100644 --- a/tests/test_data/aggregate_all_epitopes/HCC1395.output.metrics.json +++ b/tests/test_data/aggregate_all_epitopes/HCC1395.output.metrics.json @@ -4429,24 +4429,24 @@ } }, "transcripts": [ - "ENST00000373151.6-MAP7D1-EE/EK-764-765", - "ENST00000474796.2-MAP7D1-EE/EK-763-764" + "ENST00000474796.2-MAP7D1-EE/EK-763-764", + "ENST00000373151.6-MAP7D1-EE/EK-764-765" ], "transcript_expr": [ - 6.418, - 24.171 + 24.171, + 6.418 ], "mane_select": [ - false, - true + true, + false ], "canonical": [ - false, - true + true, + false ], "tsl": [ - 1, - 2 + 2, + 1 ], "biotype": [ "protein_coding", @@ -4457,8 +4457,8 @@ "None" ], "transcript_length": [ - 841, - 840 + 840, + 841 ], "transcript_count": 2, "peptide_count": 2, @@ -5396,24 +5396,24 @@ } }, "transcripts": [ - "ENST00000373151.6-MAP7D1-E/K-765", - "ENST00000474796.2-MAP7D1-E/K-764" + "ENST00000474796.2-MAP7D1-E/K-764", + "ENST00000373151.6-MAP7D1-E/K-765" ], "transcript_expr": [ - 6.418, - 24.171 + 24.171, + 6.418 ], "mane_select": [ - false, - true + true, + false ], "canonical": [ - false, - true + true, + false ], "tsl": [ - 1, - 2 + 2, + 1 ], "biotype": [ "protein_coding", @@ -5424,8 +5424,8 @@ "None" ], "transcript_length": [ - 841, - 840 + 840, + 841 ], "transcript_count": 2, "peptide_count": 1, @@ -20791,12 +20791,12 @@ } }, "transcripts": [ - "ENST00000648311.1-ADAR-E/V-511", - "ENST00000649022.2-ADAR-E/V-511" + "ENST00000649022.2-ADAR-E/V-511", + "ENST00000648311.1-ADAR-E/V-511" ], "transcript_expr": [ - 0.922, - 1.143 + 1.143, + 0.922 ], "mane_select": [ false, @@ -22553,6 +22553,247 @@ "chr1-183880710-183880711-A-C": { "good_binders": { "Transcript Set 1": { + "peptides": { + "FPCLQKLLDSL": { + "ic50s_MT": [ + "X", + "X", + 1268.8189697265625, + "X" + ], + "percentiles_MT": [ + "X", + "X", + 0.8100000023841858, + "X" + ], + "ic50s_WT": [ + "X", + "X", + 4927.84, + "X" + ], + "percentiles_WT": [ + "X", + "X", + 1.3, + "X" + ], + "hla_types": [ + "HLA-A*29:02", + "HLA-B*45:01", + "HLA-B*82:02", + "HLA-C*06:02" + ], + "mutation_position": "10", + "problematic_positions": "3", + "anchor_fails": "None", + "individual_ic50_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-B*82:02": [ + 1268.819402964555, + 2219.08, + "NA", + 979.25, + 5786.34, + 418.82, + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + 7056.01709911214, + 4927.84, + "NA", + 1691.19, + 7478.54, + 719.41, + "NA", + "NA" + ] + } + }, + "individual_ic50_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-B*82:02": [ + 0.29512500762939453, + 3.799999952316284, + "NA", + 0.5099999904632568, + 0.8100000023841858, + 0.4000000059604645, + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + 0.9962499999999992, + 6.36, + "NA", + 1.3, + 1.3, + 1.0, + "NA", + "NA" + ] + } + }, + "individual_el_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-B*82:02": [ + 0.0847564720315858, + 0.0896967400655027, + 0.0993, + 0.00046540843, + 0.0027159, + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + 0.17476629500743, + 0.0249523360944381, + 0.0511, + 0.00020804231, + 0.0035485458, + "NA" + ] + } + }, + "individual_el_percentile_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-B*82:02": [ + "NA", + 3.1588586956520857, + 0.88, + "NA", + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + "NA", + 9.849456521739114, + 1.8, + "NA", + "NA", + "NA" + ] + } + }, + "individual_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC", + "MHCflurryEL Presentation", + "NetMHCpanEL" + ], + "MT": { + "HLA-B*82:02": [ + 0.29512500762939453, + 3.799999952316284, + "NA", + 0.5099999904632568, + 0.8100000023841858, + 0.4000000059604645, + "NA", + "NA", + 3.1588586956520857, + 0.88 + ] + }, + "WT": { + "HLA-B*82:02": [ + 0.9962499999999992, + 6.36, + "NA", + 1.3, + 1.3, + 1.0, + "NA", + "NA", + 9.849456521739114, + 1.8 + ] + } + }, + "wt_peptide": "FPCLQKLLDYL" + } + }, + "transcripts": [ + "ENST00000304685.8-RGL1-Y/S-209" + ], + "transcript_expr": [ + 0.449 + ], + "mane_select": [ + false + ], + "canonical": [ + false + ], + "tsl": [ + 1 + ], + "biotype": [ + "protein_coding" + ], + "transcript_cds_flags": [ + "None" + ], + "transcript_length": [ + 803 + ], + "transcript_count": 1, + "peptide_count": 1, + "total_expr": 0.449 + }, + "Transcript Set 2": { "peptides": { "LLDSLTRMM": { "ic50s_MT": [ @@ -22975,247 +23216,6 @@ "wt_peptide": "FPCLQKLLDYL" } }, - "transcripts": [ - "ENST00000304685.8-RGL1-Y/S-209" - ], - "transcript_expr": [ - 0.449 - ], - "mane_select": [ - false - ], - "canonical": [ - false - ], - "tsl": [ - 1 - ], - "biotype": [ - "protein_coding" - ], - "transcript_cds_flags": [ - "None" - ], - "transcript_length": [ - 803 - ], - "transcript_count": 1, - "peptide_count": 2, - "total_expr": 0.449 - }, - "Transcript Set 2": { - "peptides": { - "FPCLQKLLDSL": { - "ic50s_MT": [ - "X", - "X", - 1268.8189697265625, - "X" - ], - "percentiles_MT": [ - "X", - "X", - 0.8100000023841858, - "X" - ], - "ic50s_WT": [ - "X", - "X", - 4927.84, - "X" - ], - "percentiles_WT": [ - "X", - "X", - 1.3, - "X" - ], - "hla_types": [ - "HLA-A*29:02", - "HLA-B*45:01", - "HLA-B*82:02", - "HLA-C*06:02" - ], - "mutation_position": "10", - "problematic_positions": "3", - "anchor_fails": "None", - "individual_ic50_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC" - ], - "MT": { - "HLA-B*82:02": [ - 1268.819402964555, - 2219.08, - "NA", - 979.25, - 5786.34, - 418.82, - "NA", - "NA" - ] - }, - "WT": { - "HLA-B*82:02": [ - 7056.01709911214, - 4927.84, - "NA", - 1691.19, - 7478.54, - 719.41, - "NA", - "NA" - ] - } - }, - "individual_ic50_percentile_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC" - ], - "MT": { - "HLA-B*82:02": [ - 0.29512500762939453, - 3.799999952316284, - "NA", - 0.5099999904632568, - 0.8100000023841858, - 0.4000000059604645, - "NA", - "NA" - ] - }, - "WT": { - "HLA-B*82:02": [ - 0.9962499999999992, - 6.36, - "NA", - 1.3, - 1.3, - 1.0, - "NA", - "NA" - ] - } - }, - "individual_el_calls": { - "algorithms": [ - "MHCflurryEL Processing", - "MHCflurryEL Presentation", - "NetMHCpanEL", - "BigMHC_EL", - "BigMHC_IM", - "DeepImmuno" - ], - "MT": { - "HLA-B*82:02": [ - 0.0847564720315858, - 0.0896967400655027, - 0.0993, - 0.00046540843, - 0.0027159, - "NA" - ] - }, - "WT": { - "HLA-B*82:02": [ - 0.17476629500743, - 0.0249523360944381, - 0.0511, - 0.00020804231, - 0.0035485458, - "NA" - ] - } - }, - "individual_el_percentile_calls": { - "algorithms": [ - "MHCflurryEL Processing", - "MHCflurryEL Presentation", - "NetMHCpanEL", - "BigMHC_EL", - "BigMHC_IM", - "DeepImmuno" - ], - "MT": { - "HLA-B*82:02": [ - "NA", - 3.1588586956520857, - 0.88, - "NA", - "NA", - "NA" - ] - }, - "WT": { - "HLA-B*82:02": [ - "NA", - 9.849456521739114, - 1.8, - "NA", - "NA", - "NA" - ] - } - }, - "individual_percentile_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC", - "MHCflurryEL Presentation", - "NetMHCpanEL" - ], - "MT": { - "HLA-B*82:02": [ - 0.29512500762939453, - 3.799999952316284, - "NA", - 0.5099999904632568, - 0.8100000023841858, - 0.4000000059604645, - "NA", - "NA", - 3.1588586956520857, - 0.88 - ] - }, - "WT": { - "HLA-B*82:02": [ - 0.9962499999999992, - 6.36, - "NA", - 1.3, - 1.3, - 1.0, - "NA", - "NA", - 9.849456521739114, - 1.8 - ] - } - }, - "wt_peptide": "FPCLQKLLDYL" - } - }, "transcripts": [ "ENST00000360851.4-RGL1-Y/S-174" ], @@ -23241,7 +23241,7 @@ 768 ], "transcript_count": 1, - "peptide_count": 1, + "peptide_count": 2, "total_expr": 0.012 } }, @@ -23254,8 +23254,8 @@ 1 ], "peptide_counts": [ - 2, - 1 + 1, + 2 ], "set_expr": [ 0.449, @@ -30074,15 +30074,15 @@ }, "transcripts": [ "ENST00000344029.6-SUSD4-L/V-228", + "ENST00000484758.6-SUSD4-L/V-157", "ENST00000494793.6-SUSD4-L/V-228", - "ENST00000608996.5-SUSD4-L/V-199", - "ENST00000484758.6-SUSD4-L/V-157" + "ENST00000608996.5-SUSD4-L/V-199" ], "transcript_expr": [ 8.645, 0.0, - 4.336, - 0.0 + 0.0, + 4.336 ], "mane_select": [ false, @@ -30098,9 +30098,9 @@ ], "tsl": [ 1, + 2, 5, - 5, - 2 + 5 ], "biotype": [ "protein_coding", @@ -30116,9 +30116,9 @@ ], "transcript_length": [ 290, + 421, 488, - 463, - 421 + 463 ], "transcript_count": 4, "peptide_count": 1, @@ -36684,12 +36684,12 @@ } }, "transcripts": [ - "ENST00000277657.12-CCDC7-S/L-454", - "ENST00000362006.11-CCDC7-S/L-454" + "ENST00000362006.11-CCDC7-S/L-454", + "ENST00000277657.12-CCDC7-S/L-454" ], "transcript_expr": [ - 0.534, - 0.611 + 0.611, + 0.534 ], "mane_select": [ false, @@ -49910,14 +49910,14 @@ } }, "transcripts": [ + "ENST00000525334.5-TSPAN4-I/M-3", "ENST00000525201.5-TSPAN4-I/M-3", - "ENST00000397396.5-TSPAN4-I/M-3", - "ENST00000525334.5-TSPAN4-I/M-3" + "ENST00000397396.5-TSPAN4-I/M-3" ], "transcript_expr": [ + 0.483, 1.8, - 1.654, - 0.483 + 1.654 ], "mane_select": [ false, @@ -49930,9 +49930,9 @@ false ], "tsl": [ + 3, 5, - 5, - 3 + 5 ], "biotype": [ "protein_coding", @@ -49945,9 +49945,9 @@ "None" ], "transcript_length": [ + 100, 174, - 174, - 100 + 174 ], "transcript_count": 3, "peptide_count": 1, @@ -65671,12 +65671,12 @@ } }, "transcripts": [ - "ENST00000354445.2-PLAAT4-CEHFVTQL/CX-113-120", - "ENST00000439013.6-PLAAT4-CEHFVTQL/CX-113-120" + "ENST00000439013.6-PLAAT4-CEHFVTQL/CX-113-120", + "ENST00000354445.2-PLAAT4-CEHFVTQL/CX-113-120" ], "transcript_expr": [ - 0.0, - 0.063 + 0.063, + 0.0 ], "mane_select": [ false, @@ -65687,8 +65687,8 @@ false ], "tsl": [ - 5, - 2 + 2, + 5 ], "biotype": [ "protein_coding", @@ -65699,8 +65699,8 @@ "None" ], "transcript_length": [ - 164, - 156 + 156, + 164 ], "transcript_count": 2, "peptide_count": 1, @@ -71864,30 +71864,30 @@ "good_binders": { "Transcript Set 1": { "peptides": { - "LLNSLSVDL": { + "LDAECKYGLY": { "ic50s_MT": [ + 1185.83203125, "X", "X", - "X", - 5793.85986328125 + "X" ], "percentiles_MT": [ + 2.1500000953674316, "X", "X", - "X", - 9.350000381469727 + "X" ], "ic50s_WT": [ + 4118.843, "X", "X", - "X", - 20782.765 + "X" ], "percentiles_WT": [ + 6.4, "X", "X", - "X", - 50.859 + "X" ], "hla_types": [ "HLA-A*29:02", @@ -71895,8 +71895,8 @@ "HLA-B*82:02", "HLA-C*06:02" ], - "mutation_position": "9", - "problematic_positions": "None", + "mutation_position": "1", + "problematic_positions": "5", "anchor_fails": "None", "individual_ic50_calls": { "algorithms": [ @@ -71910,27 +71910,27 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 3453.5809819284395, - 785.3, - 20331.13, - 14963.56, - 19279.63, - 7692.16, - 3497.92, - 3895.56 + "HLA-A*29:02": [ + 1404.4349455665078, + 5631.94, + 697.11, + 474.31, + 1553.24, + 10992.95, + 478.94, + 967.23 ] }, "WT": { - "HLA-C*06:02": [ - 23410.01904324579, - 18155.51, - 39246.2, - 41599.44, - 43020.27, - 16404.99, - 11989.75, - 12751.76 + "HLA-A*29:02": [ + 5529.596718725659, + 5764.07, + 2708.09, + 2621.2, + 12106.79, + 29745.37, + 682.78, + 2044.23 ] } }, @@ -71946,27 +71946,27 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 6.698999881744385, - 3.5799999237060547, - 8.800000190734863, - 16.0, - 7.5, - 27.0, - 20.0, - 22.0 + "HLA-A*29:02": [ + 1.9594999551773071, + 8.819999694824219, + 1.399999976158142, + 2.0, + 1.399999976158142, + 12.0, + 2.1, + 3.7 ] }, "WT": { - "HLA-C*06:02": [ - 50.71774999999999, - 33.67, - 40.0, - 77.0, - 71.0, - 51.0, - 36.0, - 37.0 + "HLA-A*29:02": [ + 3.573999999999999, + 15.81, + 2.9, + 4.1, + 6.5, + 32.0, + 2.8, + 6.3 ] } }, @@ -71980,23 +71980,23 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ - 0.0212356689153239, - 0.0288960593629738, - 0.000795, - 0.0006750826, - 0.012569367, - 0.98502254 + "HLA-A*29:02": [ + 0.1038067035842686, + 0.087178680498477, + 0.0216, + 0.16269091, + 0.8683477, + "NA" ] }, "WT": { - "HLA-C*06:02": [ - 0.0022862036603328, - 0.0043177077986462, - 2e-06, - 0.00010387441, - 0.0065268567, - 0.98747575 + "HLA-A*29:02": [ + 0.0662135537713766, + 0.0216087819885557, + 0.00115, + 0.060722344, + 0.67997503, + "NA" ] } }, @@ -72010,20 +72010,20 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ + "HLA-A*29:02": [ "NA", - 8.545326086956507, - 9.9, + 3.2120380434781595, + 2.2, "NA", "NA", "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-A*29:02": [ "NA", - 62.74467391304348, - 73.0, + 11.115788043478249, + 8.9, "NA", "NA", "NA" @@ -72044,57 +72044,57 @@ "NetMHCpanEL" ], "MT": { - "HLA-C*06:02": [ - 6.698999881744385, - 3.5799999237060547, - 8.800000190734863, - 16.0, - 7.5, - 27.0, - 20.0, - 22.0, - 8.545326086956507, - 9.9 + "HLA-A*29:02": [ + 1.9594999551773071, + 8.819999694824219, + 1.399999976158142, + 2.0, + 1.399999976158142, + 12.0, + 2.1, + 3.7, + 3.2120380434781595, + 2.2 ] }, "WT": { - "HLA-C*06:02": [ - 50.71774999999999, - 33.67, - 40.0, - 77.0, - 71.0, - 51.0, - 36.0, - 37.0, - 62.74467391304348, - 73.0 + "HLA-A*29:02": [ + 3.573999999999999, + 15.81, + 2.9, + 4.1, + 6.5, + 32.0, + 2.8, + 6.3, + 11.115788043478249, + 8.9 ] } }, - "wt_peptide": "LLNSLSVDP" + "wt_peptide": "PDAECKYGLY" }, - "LDAECKYGLY": { + "SVDLDAECKY": { "ic50s_MT": [ - 1185.83203125, + 1355.64501953125, "X", "X", "X" ], "percentiles_MT": [ - 2.1500000953674316, + 2.4649999141693115, "X", "X", "X" ], "ic50s_WT": [ - 4118.843, + 2145.36, "X", "X", "X" ], "percentiles_WT": [ - 6.4, + 2.7, "X", "X", "X" @@ -72105,8 +72105,8 @@ "HLA-B*82:02", "HLA-C*06:02" ], - "mutation_position": "1", - "problematic_positions": "5", + "mutation_position": "4", + "problematic_positions": "8", "anchor_fails": "None", "individual_ic50_calls": { "algorithms": [ @@ -72121,26 +72121,26 @@ ], "MT": { "HLA-A*29:02": [ - 1404.4349455665078, - 5631.94, - 697.11, - 474.31, - 1553.24, - 10992.95, - 478.94, - 967.23 + 198.58565008451492, + 5037.51, + 2315.01, + 1602.13, + 1109.16, + 11986.87, + 1019.25, + 852.18 ] }, "WT": { "HLA-A*29:02": [ - 5529.596718725659, - 5764.07, - 2708.09, - 2621.2, - 12106.79, - 29745.37, - 682.78, - 2044.23 + 86.40535329686892, + 4146.26, + 4180.0, + 1619.56, + 2671.16, + 9146.01, + 1242.45, + 1080.26 ] } }, @@ -72157,26 +72157,26 @@ ], "MT": { "HLA-A*29:02": [ - 1.9594999551773071, - 8.819999694824219, - 1.399999976158142, - 2.0, - 1.399999976158142, - 12.0, - 2.1, - 3.7 + 0.7538750171661377, + 2.3299999237060547, + 2.5999999046325684, + 3.5, + 1.2000000476837158, + 13.0, + 3.9, + 3.4 ] }, "WT": { "HLA-A*29:02": [ - 3.573999999999999, - 15.81, - 2.9, - 4.1, - 6.5, - 32.0, - 2.8, - 6.3 + 0.3716249999999998, + 0.97, + 3.8, + 3.5, + 1.9, + 8.5, + 4.4, + 4.0 ] } }, @@ -72191,21 +72191,21 @@ ], "MT": { "HLA-A*29:02": [ - 0.1038067035842686, - 0.087178680498477, - 0.0216, - 0.16269091, - 0.8683477, + 0.2347290618345141, + 0.5036928850648045, + 0.226, + 0.052869927, + 0.64994764, "NA" ] }, "WT": { "HLA-A*29:02": [ - 0.0662135537713766, - 0.0216087819885557, - 0.00115, - 0.060722344, - 0.67997503, + 0.4763666223734617, + 0.8426459651827981, + 0.255, + 0.070154004, + 0.48715687, "NA" ] } @@ -72222,8 +72222,8 @@ "MT": { "HLA-A*29:02": [ "NA", - 3.2120380434781595, - 2.2, + 0.8127173913042185, + 0.49, "NA", "NA", "NA" @@ -72232,218 +72232,8 @@ "WT": { "HLA-A*29:02": [ "NA", - 11.115788043478249, - 8.9, - "NA", - "NA", - "NA" - ] - } - }, - "individual_percentile_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC", - "MHCflurryEL Presentation", - "NetMHCpanEL" - ], - "MT": { - "HLA-A*29:02": [ - 1.9594999551773071, - 8.819999694824219, - 1.399999976158142, - 2.0, - 1.399999976158142, - 12.0, - 2.1, - 3.7, - 3.2120380434781595, - 2.2 - ] - }, - "WT": { - "HLA-A*29:02": [ - 3.573999999999999, - 15.81, - 2.9, - 4.1, - 6.5, - 32.0, - 2.8, - 6.3, - 11.115788043478249, - 8.9 - ] - } - }, - "wt_peptide": "PDAECKYGLY" - }, - "SVDLDAECKY": { - "ic50s_MT": [ - 1355.64501953125, - "X", - "X", - "X" - ], - "percentiles_MT": [ - 2.4649999141693115, - "X", - "X", - "X" - ], - "ic50s_WT": [ - 2145.36, - "X", - "X", - "X" - ], - "percentiles_WT": [ - 2.7, - "X", - "X", - "X" - ], - "hla_types": [ - "HLA-A*29:02", - "HLA-B*45:01", - "HLA-B*82:02", - "HLA-C*06:02" - ], - "mutation_position": "4", - "problematic_positions": "8", - "anchor_fails": "None", - "individual_ic50_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC" - ], - "MT": { - "HLA-A*29:02": [ - 198.58565008451492, - 5037.51, - 2315.01, - 1602.13, - 1109.16, - 11986.87, - 1019.25, - 852.18 - ] - }, - "WT": { - "HLA-A*29:02": [ - 86.40535329686892, - 4146.26, - 4180.0, - 1619.56, - 2671.16, - 9146.01, - 1242.45, - 1080.26 - ] - } - }, - "individual_ic50_percentile_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC" - ], - "MT": { - "HLA-A*29:02": [ - 0.7538750171661377, - 2.3299999237060547, - 2.5999999046325684, - 3.5, - 1.2000000476837158, - 13.0, - 3.9, - 3.4 - ] - }, - "WT": { - "HLA-A*29:02": [ - 0.3716249999999998, - 0.97, - 3.8, - 3.5, - 1.9, - 8.5, - 4.4, - 4.0 - ] - } - }, - "individual_el_calls": { - "algorithms": [ - "MHCflurryEL Processing", - "MHCflurryEL Presentation", - "NetMHCpanEL", - "BigMHC_EL", - "BigMHC_IM", - "DeepImmuno" - ], - "MT": { - "HLA-A*29:02": [ - 0.2347290618345141, - 0.5036928850648045, - 0.226, - 0.052869927, - 0.64994764, - "NA" - ] - }, - "WT": { - "HLA-A*29:02": [ - 0.4763666223734617, - 0.8426459651827981, - 0.255, - 0.070154004, - 0.48715687, - "NA" - ] - } - }, - "individual_el_percentile_calls": { - "algorithms": [ - "MHCflurryEL Processing", - "MHCflurryEL Presentation", - "NetMHCpanEL", - "BigMHC_EL", - "BigMHC_IM", - "DeepImmuno" - ], - "MT": { - "HLA-A*29:02": [ - "NA", - 0.8127173913042185, - 0.49, - "NA", - "NA", - "NA" - ] - }, - "WT": { - "HLA-A*29:02": [ - "NA", - 0.2122010869565258, - 0.44, + 0.2122010869565258, + 0.44, "NA", "NA", "NA" @@ -72730,7 +72520,7 @@ 1049 ], "transcript_count": 1, - "peptide_count": 4, + "peptide_count": 3, "total_expr": 0.0 }, "Transcript Set 2": { @@ -73847,6 +73637,216 @@ }, "Transcript Set 4": { "peptides": { + "LLNSLSVDL": { + "ic50s_MT": [ + "X", + "X", + "X", + 5793.85986328125 + ], + "percentiles_MT": [ + "X", + "X", + "X", + 9.350000381469727 + ], + "ic50s_WT": [ + "X", + "X", + "X", + 20782.765 + ], + "percentiles_WT": [ + "X", + "X", + "X", + 50.859 + ], + "hla_types": [ + "HLA-A*29:02", + "HLA-B*45:01", + "HLA-B*82:02", + "HLA-C*06:02" + ], + "mutation_position": "9", + "problematic_positions": "None", + "anchor_fails": "None", + "individual_ic50_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-C*06:02": [ + 3453.5809819284395, + 785.3, + 20331.13, + 14963.56, + 19279.63, + 7692.16, + 3497.92, + 3895.56 + ] + }, + "WT": { + "HLA-C*06:02": [ + 23410.01904324579, + 18155.51, + 39246.2, + 41599.44, + 43020.27, + 16404.99, + 11989.75, + 12751.76 + ] + } + }, + "individual_ic50_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-C*06:02": [ + 6.698999881744385, + 3.5799999237060547, + 8.800000190734863, + 16.0, + 7.5, + 27.0, + 20.0, + 22.0 + ] + }, + "WT": { + "HLA-C*06:02": [ + 50.71774999999999, + 33.67, + 40.0, + 77.0, + 71.0, + 51.0, + 36.0, + 37.0 + ] + } + }, + "individual_el_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-C*06:02": [ + 0.0212356689153239, + 0.0288960593629738, + 0.000795, + 0.0006750826, + 0.012569367, + 0.98502254 + ] + }, + "WT": { + "HLA-C*06:02": [ + 0.0022862036603328, + 0.0043177077986462, + 2e-06, + 0.00010387441, + 0.0065268567, + 0.98747575 + ] + } + }, + "individual_el_percentile_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-C*06:02": [ + "NA", + 8.545326086956507, + 9.9, + "NA", + "NA", + "NA" + ] + }, + "WT": { + "HLA-C*06:02": [ + "NA", + 62.74467391304348, + 73.0, + "NA", + "NA", + "NA" + ] + } + }, + "individual_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC", + "MHCflurryEL Presentation", + "NetMHCpanEL" + ], + "MT": { + "HLA-C*06:02": [ + 6.698999881744385, + 3.5799999237060547, + 8.800000190734863, + 16.0, + 7.5, + 27.0, + 20.0, + 22.0, + 8.545326086956507, + 9.9 + ] + }, + "WT": { + "HLA-C*06:02": [ + 50.71774999999999, + 33.67, + 40.0, + 77.0, + 71.0, + 51.0, + 36.0, + 37.0, + 62.74467391304348, + 73.0 + ] + } + }, + "wt_peptide": "LLNSLSVDP" + }, "SVDLDAECKY": { "ic50s_MT": [ 1355.64501953125, @@ -74083,7 +74083,7 @@ 986 ], "transcript_count": 1, - "peptide_count": 1, + "peptide_count": 2, "total_expr": 0.065 } }, @@ -74100,10 +74100,10 @@ 1 ], "peptide_counts": [ - 4, + 3, 4, 1, - 1 + 2 ], "set_expr": [ 0.0, @@ -83627,24 +83627,24 @@ } }, "transcripts": [ - "ENST00000321898.10-SPATS2-R/H-533", - "ENST00000552918.6-SPATS2-R/H-533" + "ENST00000552918.6-SPATS2-R/H-533", + "ENST00000321898.10-SPATS2-R/H-533" ], "transcript_expr": [ - 8.69, - 6.225 + 6.225, + 8.69 ], "mane_select": [ - false, - true + true, + false ], "canonical": [ - false, - true + true, + false ], "tsl": [ - 1, - 2 + 2, + 1 ], "biotype": [ "protein_coding", @@ -89392,8 +89392,8 @@ } }, "transcripts": [ - "ENST00000625583.2-TRPC4-E/K-138", "ENST00000379705.8-TRPC4-E/K-138", + "ENST00000625583.2-TRPC4-E/K-138", "ENST00000379673.2-TRPC4-E/K-138", "ENST00000426868.6-TRPC4-E/K-138" ], @@ -89404,15 +89404,15 @@ 0.0 ], "mane_select": [ - false, true, false, + false, false ], "canonical": [ - false, true, false, + false, false ], "tsl": [ @@ -89434,8 +89434,8 @@ "None" ], "transcript_length": [ - 982, 977, + 982, 828, 460 ], @@ -92532,12 +92532,12 @@ } }, "transcripts": [ - "ENST00000627049.2-FARP1-R/L-714", - "ENST00000596256.1-FARP1-R/L-67" + "ENST00000596256.1-FARP1-R/L-67", + "ENST00000627049.2-FARP1-R/L-714" ], "transcript_expr": [ - 5.332, - 0.0 + 0.0, + 5.332 ], "mane_select": [ false, @@ -92548,8 +92548,8 @@ false ], "tsl": [ - 5, - 3 + 3, + 5 ], "biotype": [ "protein_coding", @@ -92560,8 +92560,8 @@ "None" ], "transcript_length": [ - 1076, - 248 + 248, + 1076 ], "transcript_count": 2, "peptide_count": 5, @@ -115327,17 +115327,17 @@ }, "wt_peptide": "FS-NA" }, - "LPGQLPVPL": { + "GPSLPLPPV": { "ic50s_MT": [ "X", "X", - 158.55999755859375, + 335.4670104980469, "X" ], "percentiles_MT": [ "X", "X", - 0.07999999821186066, + 0.4000000059604645, "X" ], "ic50s_WT": [ @@ -115374,12 +115374,222 @@ ], "MT": { "HLA-B*82:02": [ - 121.71276475922818, - 158.56, + 335.4672341488855, + 238.42, + "NA", + 814.73, + 1907.0, + 196.38, + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + "NA", + "NA", + "NA", + "NA", + "NA", + "NA", + "NA", + "NA" + ] + } + }, + "individual_ic50_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-B*82:02": [ + 0.08487500250339508, + 0.8100000023841858, + "NA", + 0.7400000095367432, + 0.17000000178813934, + 0.4000000059604645, "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + "NA", + "NA", + "NA", + "NA", + "NA", + "NA", + "NA", + "NA" + ] + } + }, + "individual_el_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-B*82:02": [ + 0.0222264141921186, + 0.223328403982173, + 0.296, + 0.029245984, + 0.004468919, + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + "NA", + "NA", + "NA", + "NA", + "NA", + "NA" + ] + } + }, + "individual_el_percentile_calls": { + "algorithms": [ + "MHCflurryEL Processing", + "MHCflurryEL Presentation", + "NetMHCpanEL", + "BigMHC_EL", + "BigMHC_IM", + "DeepImmuno" + ], + "MT": { + "HLA-B*82:02": [ + "NA", + 1.6983695652173054, + 0.16, + "NA", + "NA", + "NA" + ] + }, + "WT": { + "HLA-B*82:02": [ + "NA", + "NA", + "NA", + "NA", + "NA", + "NA" + ] + } + }, + "individual_percentile_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC", + "MHCflurryEL Presentation", + "NetMHCpanEL" + ], + "MT": { + "HLA-B*82:02": [ + 0.08487500250339508, + 0.8100000023841858, + "NA", + 0.7400000095367432, + 0.17000000178813934, + 0.4000000059604645, + "NA", + "NA", + 1.6983695652173054, + 0.16 + ] + }, + "WT": { + "HLA-B*82:02": [ + "NA", + "NA", + "NA", + "NA", + "NA", + "NA", + "NA", + "NA", + "NA", + "NA" + ] + } + }, + "wt_peptide": "FS-NA" + }, + "LPGVRHPPV": { + "ic50s_MT": [ + "X", + "X", + 367.38299560546875, + "X" + ], + "percentiles_MT": [ + "X", + "X", + 0.3100000023841858, + "X" + ], + "ic50s_WT": [ + "X", + "X", + "NA", + "X" + ], + "percentiles_WT": [ + "X", + "X", + "NA", + "X" + ], + "hla_types": [ + "HLA-A*29:02", + "HLA-B*45:01", + "HLA-B*82:02", + "HLA-C*06:02" + ], + "mutation_position": "NA", + "problematic_positions": "None", + "anchor_fails": "None", + "individual_ic50_calls": { + "algorithms": [ + "MHCflurry", + "MHCnuggetsI", + "NetMHC", + "NetMHCcons", + "NetMHCpan", + "PickPocket", + "SMM", + "SMMPMBEC" + ], + "MT": { + "HLA-B*82:02": [ + 367.3827758769957, + 56.38, + "NA", + 503.39, + 956.77, 263.01, - 576.13, - 101.5, "NA", "NA" ] @@ -115410,12 +115620,12 @@ ], "MT": { "HLA-B*82:02": [ - 0.010999999940395355, - 0.5699999928474426, + 0.09437499940395355, + 0.18000000715255737, "NA", + 0.3100000023841858, 0.07999999821186066, - 0.03999999910593033, - 0.20000000298023224, + 0.699999988079071, "NA", "NA" ] @@ -115444,11 +115654,11 @@ ], "MT": { "HLA-B*82:02": [ - 0.0534636205411516, - 0.4623125207384621, - 0.491, - 0.010877984, - 0.0064323805, + 0.0440800187643617, + 0.2214338679591464, + 0.205, + 0.0034731566, + 0.012823993, "NA" ] }, @@ -115475,8 +115685,8 @@ "MT": { "HLA-B*82:02": [ "NA", - 0.9059239130433668, - 0.05, + 1.7091576086955769, + 0.32, "NA", "NA", "NA" @@ -115508,16 +115718,16 @@ ], "MT": { "HLA-B*82:02": [ - 0.010999999940395355, - 0.5699999928474426, + 0.09437499940395355, + 0.18000000715255737, "NA", + 0.3100000023841858, 0.07999999821186066, - 0.03999999910593033, - 0.20000000298023224, + 0.699999988079071, "NA", "NA", - 0.9059239130433668, - 0.05 + 1.7091576086955769, + 0.32 ] }, "WT": { @@ -115537,30 +115747,30 @@ }, "wt_peptide": "FS-NA" }, - "GPSLPLPPV": { + "GREPAPRVL": { "ic50s_MT": [ "X", "X", - 335.4670104980469, - "X" + "X", + 526.875 ], "percentiles_MT": [ "X", "X", - 0.4000000059604645, - "X" + "X", + 0.5249999761581421 ], "ic50s_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "percentiles_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "hla_types": [ "HLA-A*29:02", @@ -115583,19 +115793,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 335.4672341488855, - 238.42, - "NA", - 814.73, - 1907.0, - 196.38, - "NA", - "NA" + "HLA-C*06:02": [ + 83.763930129218, + 24949.85, + 648.43, + 461.65, + 1895.79, + 592.1, + 48.96, + 80.46 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -115619,19 +115829,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 0.08487500250339508, - 0.8100000023841858, - "NA", - 0.7400000095367432, - 0.17000000178813934, - 0.4000000059604645, - "NA", - "NA" + "HLA-C*06:02": [ + 0.22762499749660492, + 47.470001220703125, + 0.23999999463558197, + 0.6299999952316284, + 0.41999998688697815, + 0.699999988079071, + 0.9, + 1.3 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -115653,17 +115863,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.0222264141921186, - 0.223328403982173, - 0.296, - 0.029245984, - 0.004468919, - "NA" + "HLA-C*06:02": [ + 0.4152056146413088, + 0.8163499110383341, + 0.464, + 0.26677617, + 0.0141969025, + 0.97908276 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -115683,17 +115893,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", - 1.6983695652173054, - 0.16, + 0.2525815217391169, + 0.06, "NA", "NA", "NA" ] }, "WT": { - 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@@ -115830,12 +116040,12 @@ ], "MT": { "HLA-B*82:02": [ - 0.09437499940395355, - 0.18000000715255737, + 0.008750000037252903, + 2.0899999141693115, "NA", - 0.3100000023841858, - 0.07999999821186066, - 0.699999988079071, + 0.5299999713897705, + 0.5, + 0.5, "NA", "NA" ] @@ -115864,11 +116074,11 @@ ], "MT": { "HLA-B*82:02": [ - 0.0440800187643617, - 0.2214338679591464, - 0.205, - 0.0034731566, - 0.012823993, + 0.3753255642950535, + 0.743322291249028, + 0.251, + 0.08228921, + 0.04480669, "NA" ] }, @@ -115895,8 +116105,8 @@ "MT": { "HLA-B*82:02": [ "NA", - 1.7091576086955769, - 0.32, + 0.3685326086956451, + 0.22, "NA", "NA", "NA" @@ -115928,16 +116138,16 @@ ], "MT": { "HLA-B*82:02": [ - 0.09437499940395355, - 0.18000000715255737, + 0.008750000037252903, + 2.0899999141693115, "NA", - 0.3100000023841858, - 0.07999999821186066, - 0.699999988079071, + 0.5299999713897705, + 0.5, + 0.5, "NA", "NA", - 1.7091576086955769, - 0.32 + 0.3685326086956451, + 0.22 ] }, "WT": { @@ -115957,18 +116167,18 @@ }, "wt_peptide": "FS-NA" }, - "VRHPPVREH": { + "YRAGGGLPGQL": { "ic50s_MT": [ "X", "X", "X", - 381.406005859375 + 915.7150268554688 ], "percentiles_MT": [ "X", "X", "X", - 0.6000000238418579 + 0.5789999961853027 ], "ic50s_WT": [ "X", @@ -116004,14 +116214,14 @@ ], "MT": { "HLA-C*06:02": [ - 164.27231850781482, - 8177.5, - 107.27, - 652.65, - 3107.46, - 598.54, - 3.46, - 17.32 + 103.5873091078729, + 297.87, + 19114.51, + 282.17, + 1533.56, + 3766.31, + "NA", + "NA" ] }, "WT": { @@ -116040,14 +116250,14 @@ ], "MT": { "HLA-C*06:02": [ - 0.6056249737739563, - 16.790000915527344, - 0.05999999865889549, - 0.800000011920929, - 0.699999988079071, - 0.699999988079071, - 0.2, - 0.4 + 0.3345000147819519, + 1.9199999570846558, + 8.100000381469727, + 0.3400000035762787, + 0.3400000035762787, + 2.799999952316284, + "NA", + "NA" ] }, "WT": { @@ -116074,12 +116284,12 @@ ], "MT": { "HLA-C*06:02": [ - 0.3058738621184602, - 0.6108180467426889, - 0.398, - 0.40123963, - 0.19346094, - 0.9974298 + 0.0533772714552469, + 0.5013219711890021, + 0.192, + 0.09358336, + 0.033584353, + "NA" ] }, "WT": { @@ -116105,8 +116315,8 @@ "MT": { "HLA-C*06:02": [ "NA", - 0.594076086956477, - 0.1, + 0.8186141304346393, + 0.29, "NA", "NA", "NA" @@ -116138,16 +116348,16 @@ ], "MT": { "HLA-C*06:02": [ - 0.6056249737739563, - 16.790000915527344, - 0.05999999865889549, - 0.800000011920929, - 0.699999988079071, - 0.699999988079071, - 0.2, - 0.4, - 0.594076086956477, - 0.1 + 0.3345000147819519, + 1.9199999570846558, + 8.100000381469727, + 0.3400000035762787, + 0.3400000035762787, + 2.799999952316284, + "NA", + "NA", + 0.8186141304346393, + 0.29 ] }, "WT": { @@ -116167,17 +116377,17 @@ }, "wt_peptide": "FS-NA" }, - "RPLLHLLAAL": { + "QPDGGRPLLHL": { "ic50s_MT": [ "X", "X", - 407.6400146484375, + 977.989990234375, "X" ], "percentiles_MT": [ "X", "X", - 0.17000000178813934, + 0.800000011920929, "X" ], "ic50s_WT": [ @@ -116214,12 +116424,12 @@ ], "MT": { "HLA-B*82:02": [ - 631.8167364745673, - 55.16, + 640.1576087147172, + 977.99, "NA", - 407.64, - 664.53, - 340.99, + 1229.06, + 6307.94, + 497.98, "NA", "NA" ] @@ -116250,12 +116460,12 @@ ], "MT": { "HLA-B*82:02": [ - 0.16737499833106995, - 0.17000000178813934, + 0.16850000619888306, + 2.25, "NA", - 0.05999999865889549, - 0.05000000074505806, - 0.30000001192092896, + 0.800000011920929, + 0.9100000262260437, + 0.5, "NA", "NA" ] @@ -116284,11 +116494,11 @@ ], "MT": { "HLA-B*82:02": [ - 0.0690833257976919, - 0.1550502404555942, - 0.221, - 0.0012070949, - 0.018217355, + 0.5303559824824333, + 0.4809529869101319, + 0.392, + 0.010950968, + 0.0039295745, "NA" ] }, @@ -116315,8 +116525,8 @@ "MT": { "HLA-B*82:02": [ "NA", - 2.1829619565216376, - 0.28, + 0.8628804347825252, + 0.09, "NA", "NA", "NA" @@ -116348,16 +116558,16 @@ ], "MT": { "HLA-B*82:02": [ - 0.16737499833106995, - 0.17000000178813934, + 0.16850000619888306, + 2.25, "NA", - 0.05999999865889549, - 0.05000000074505806, - 0.30000001192092896, + 0.800000011920929, + 0.9100000262260437, + 0.5, "NA", "NA", - 2.1829619565216376, - 0.28 + 0.8628804347825252, + 0.09 ] }, "WT": { @@ -116377,30 +116587,30 @@ }, "wt_peptide": "FS-NA" }, - "SRRPVLPGV": { + "RPLLHLLAALL": { "ic50s_MT": [ "X", "X", - "X", - 502.06500244140625 + 1109.0, + "X" ], "percentiles_MT": [ "X", "X", - "X", - 0.9049999713897705 + 0.800000011920929, + "X" ], "ic50s_WT": [ "X", "X", - "X", - "NA" + "NA", + "X" ], "percentiles_WT": [ "X", "X", - "X", - "NA" + "NA", + "X" ], "hla_types": [ "HLA-A*29:02", @@ -116423,19 +116633,19 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 62.0094315747563, - 22941.75, - 3914.93, - 659.75, - 344.38, - 727.23, - 127.0, - 97.4 + "HLA-B*82:02": [ + 8796.947274506418, + 222.61, + "NA", + 1109.0, + 3400.51, + 611.63, + "NA", + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116459,19 +116669,19 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 0.11362499743700027, - 43.06999969482422, - 1.2999999523162842, - 0.8100000023841858, - 0.07999999821186066, - 1.0, - 1.9, - 1.5 + "HLA-B*82:02": [ + 1.2139999866485596, + 0.7699999809265137, + "NA", + 0.699999988079071, + 0.3499999940395355, + 0.800000011920929, + "NA", + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116493,17 +116703,17 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ - 0.2490054620429873, - 0.7677900883412523, - 0.475, - 0.015915591, - 0.07502154, - 0.9743886 + "HLA-B*82:02": [ + 0.0339964970189612, + 0.0123974762130087, + 0.0858, + 0.00041599473, + 0.0054939394, + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116523,17 +116733,17 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", - 0.3283152173912782, - 0.06, + 18.61798913043478, + 1.1, "NA", "NA", "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116557,21 +116767,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-C*06:02": [ - 0.11362499743700027, - 43.06999969482422, - 1.2999999523162842, - 0.8100000023841858, - 0.07999999821186066, - 1.0, - 1.9, - 1.5, - 0.3283152173912782, - 0.06 + "HLA-B*82:02": [ + 1.2139999866485596, + 0.7699999809265137, + "NA", + 0.699999988079071, + 0.3499999940395355, + 0.800000011920929, + "NA", + "NA", + 18.61798913043478, + 1.1 ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116587,30 +116797,30 @@ }, "wt_peptide": "FS-NA" }, - "GREPAPRVL": { + "LPVPLLRLPA": { "ic50s_MT": [ "X", "X", - "X", - 526.875 + 1177.0, + "X" ], "percentiles_MT": [ "X", "X", - "X", - 0.5249999761581421 + 1.2000000476837158, + "X" ], "ic50s_WT": [ "X", "X", - "X", - "NA" + "NA", + "X" ], "percentiles_WT": [ "X", "X", - "X", - "NA" + "NA", + "X" ], "hla_types": [ "HLA-A*29:02", @@ -116633,19 +116843,19 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 83.763930129218, - 24949.85, - 648.43, - 461.65, - 1895.79, - 592.1, - 48.96, - 80.46 + "HLA-B*82:02": [ + 2191.570832864349, + 727.88, + "NA", + 1177.0, + 2506.24, + 912.75, + "NA", + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116669,19 +116879,19 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 0.22762499749660492, - 47.470001220703125, - 0.23999999463558197, - 0.6299999952316284, - 0.41999998688697815, + "HLA-B*82:02": [ + 0.4284999966621399, + 1.840000033378601, + "NA", 0.699999988079071, - 0.9, - 1.3 + 0.25, + 1.2000000476837158, + "NA", + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116703,17 +116913,17 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ - 0.4152056146413088, - 0.8163499110383341, - 0.464, - 0.26677617, - 0.0141969025, - 0.97908276 + "HLA-B*82:02": [ + 0.2074727965518832, + 0.0821088906011905, + 0.0386, + 0.00073456543, + 0.0044832644, + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116733,17 +116943,17 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", - 0.2525815217391169, - 0.06, + 3.358777173912955, + 2.4, "NA", "NA", "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116767,21 +116977,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-C*06:02": [ - 0.22762499749660492, - 47.470001220703125, - 0.23999999463558197, - 0.6299999952316284, - 0.41999998688697815, + "HLA-B*82:02": [ + 0.4284999966621399, + 1.840000033378601, + "NA", 0.699999988079071, - 0.9, - 1.3, - 0.2525815217391169, - 0.06 + 0.25, + 1.2000000476837158, + "NA", + "NA", + 3.358777173912955, + 2.4 ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -116797,29 +117007,29 @@ }, "wt_peptide": "FS-NA" }, - "QPDGGRPL": { + "REHLHQRGL": { "ic50s_MT": [ "X", + 2246.43994140625, "X", - 707.8200073242188, "X" ], "percentiles_MT": [ "X", + 2.299999952316284, "X", - 0.39399999380111694, "X" ], "ic50s_WT": [ - "X", "X", "NA", + "X", "X" ], "percentiles_WT": [ - "X", "X", "NA", + "X", "X" ], "hla_types": [ @@ -116843,19 +117053,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 1957.8173238283944, - 351.21, - "NA", - 707.82, - 5294.62, - 274.64, - "NA", - "NA" + "HLA-B*45:01": [ + 270.3844260036878, + 12950.92, + 5474.22, + 2240.61, + 2607.94, + 598.54, + 1955.28, + 2252.27 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -116879,19 +117089,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 0.3936249911785126, - 1.100000023841858, - "NA", - 0.28999999165534973, - 0.699999988079071, - 0.20000000298023224, - "NA", - "NA" + "HLA-B*45:01": [ + 0.6014999747276306, + 13.449999809265137, + 4.5, + 2.799999952316284, + 1.2999999523162842, + 1.7999999523162842, + 7.4, + 8.4 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -116913,17 +117123,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.3335151067003608, - 0.1348755160413384, - 0.298, - 0.0056533404, - 0.013133028, + "HLA-B*45:01": [ + 0.2766908211633563, + 0.4659166337418926, + 0.249, + 0.013763225, + 0.003112162, "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -116943,17 +117153,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", - 2.390326086956435, - 0.15, + 0.897010869565122, + 0.47, "NA", "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -116977,21 +117187,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-B*82:02": [ - 0.3936249911785126, - 1.100000023841858, - "NA", - 0.28999999165534973, - 0.699999988079071, - 0.20000000298023224, - "NA", - "NA", - 2.390326086956435, - 0.15 + "HLA-B*45:01": [ + 0.6014999747276306, + 13.449999809265137, + 4.5, + 2.799999952316284, + 1.2999999523162842, + 1.7999999523162842, + 7.4, + 8.4, + 0.897010869565122, + 0.47 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -117007,29 +117217,29 @@ }, "wt_peptide": "FS-NA" }, - "VPVQPDGGRPL": { + "ITADHRPY": { "ic50s_MT": [ + 3357.68505859375, "X", "X", - 876.030029296875, "X" ], "percentiles_MT": [ + 1.9210000038146973, "X", "X", - 0.5, "X" ], "ic50s_WT": [ + 27477.815, "X", "X", - "NA", "X" ], "percentiles_WT": [ + 29.446, "X", "X", - "NA", "X" ], "hla_types": [ @@ -117038,7 +117248,7 @@ "HLA-B*82:02", "HLA-C*06:02" ], - "mutation_position": "NA", + "mutation_position": "5, 6, 7, 8", "problematic_positions": "None", "anchor_fails": "None", "individual_ic50_calls": { @@ -117053,27 +117263,27 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 112.60430901677472, - 876.03, - "NA", - 1006.1, - 4178.92, - 492.62, - "NA", - "NA" + "HLA-A*29:02": [ + 673.3450036243738, + 4616.14, + 1728.48, + 21.84, + 5464.69, + 2443.19, + 4272.18, + 13550.33 ] }, "WT": { - "HLA-B*82:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" + "HLA-A*29:02": [ + 28523.049407326296, + 5812.71, + 26432.58, + 3219.45, + 32038.23, + 8664.37, + 33239.16, + 33415.66 ] } }, @@ -117089,27 +117299,27 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 0.008750000037252903, - 2.0899999141693115, - "NA", - 0.5299999713897705, - 0.5, - 0.5, - "NA", - "NA" + "HLA-A*29:02": [ + 1.4302500486373901, + 1.4199999570846558, + 2.299999952316284, + 0.28999999165534973, + 3.0999999046325684, + 0.8999999761581421, + 2.6, + 13.0 ] }, "WT": { - "HLA-B*82:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" + "HLA-A*29:02": [ + 30.891874999999995, + 21.32, + 28.0, + 4.1, + 35.0, + 7.8, + 34.0, + 34.0 ] } }, @@ -117123,22 +117333,22 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.3753255642950535, - 0.743322291249028, - 0.251, - 0.08228921, - 0.04480669, + "HLA-A*29:02": [ + 0.0735752977197989, + 0.1491263588885815, + 0.0424, + 0.3372477, + 0.78433836, "NA" ] }, "WT": { - "HLA-B*82:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", + "HLA-A*29:02": [ + 0.0091054324439028, + 0.0036532959116699, + 0.000611, + 0.001756957, + 0.07034252, "NA" ] } @@ -117153,20 +117363,20 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-A*29:02": [ "NA", - 0.3685326086956451, - 0.22, + 2.241521739130363, + 1.6, "NA", "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ - "NA", - "NA", + "HLA-A*29:02": [ "NA", + 99.28660326086955, + 12.0, "NA", "NA", "NA" @@ -117187,48 +117397,48 @@ "NetMHCpanEL" ], "MT": { - "HLA-B*82:02": [ - 0.008750000037252903, - 2.0899999141693115, - "NA", - 0.5299999713897705, - 0.5, - 0.5, - "NA", - "NA", - 0.3685326086956451, - 0.22 + "HLA-A*29:02": [ + 1.4302500486373901, + 1.4199999570846558, + 2.299999952316284, + 0.28999999165534973, + 3.0999999046325684, + 0.8999999761581421, + 2.6, + 13.0, + 2.241521739130363, + 1.6 ] }, "WT": { - "HLA-B*82:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" + "HLA-A*29:02": [ + 30.891874999999995, + 21.32, + 28.0, + 4.1, + 35.0, + 7.8, + 34.0, + 34.0, + 99.28660326086955, + 12.0 ] } }, - "wt_peptide": "FS-NA" + "wt_peptide": "ITADNSSM" }, - "YRAGGGLPGQL": { + "HRPYHPPDA": { "ic50s_MT": [ "X", "X", "X", - 915.7150268554688 + 3435.340087890625 ], "percentiles_MT": [ "X", "X", "X", - 0.5789999961853027 + 2.4240000247955322 ], "ic50s_WT": [ "X", @@ -117264,14 +117474,14 @@ ], "MT": { "HLA-C*06:02": [ - 103.5873091078729, - 297.87, - 19114.51, - 282.17, - 1533.56, - 3766.31, - "NA", - "NA" + 835.7107258862588, + 30810.4, + 5777.83, + 8387.64, + 5580.3, + 1290.38, + 140.22, + 177.24 ] }, "WT": { @@ -117300,14 +117510,14 @@ ], "MT": { "HLA-C*06:02": [ - 0.3345000147819519, - 1.9199999570846558, - 8.100000381469727, - 0.3400000035762787, - 0.3400000035762787, - 2.799999952316284, - "NA", - "NA" + 2.448499917984009, + 61.81999969482422, + 2.0, + 7.900000095367432, + 1.5, + 2.4000000953674316, + 2.1, + 2.5 ] }, "WT": { @@ -117334,12 +117544,12 @@ ], "MT": { "HLA-C*06:02": [ - 0.0533772714552469, - 0.5013219711890021, - 0.192, - 0.09358336, - 0.033584353, - "NA" + 0.0472138517070561, + 0.1146015804753184, + 0.0362, + 0.004055911, + 0.079072304, + 0.99789274 ] }, "WT": { @@ -117365,8 +117575,8 @@ "MT": { "HLA-C*06:02": [ "NA", - 0.8186141304346393, - 0.29, + 2.660624999999925, + 1.3, "NA", "NA", "NA" @@ -117398,16 +117608,16 @@ ], "MT": { "HLA-C*06:02": [ - 0.3345000147819519, - 1.9199999570846558, - 8.100000381469727, - 0.3400000035762787, - 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"algorithms": [ - "MHCflurryEL Processing", - "MHCflurryEL Presentation", - "NetMHCpanEL", - "BigMHC_EL", - "BigMHC_IM", - "DeepImmuno" - ], - "MT": { - "HLA-B*82:02": [ - "NA", - 9.15535326086956, - 1.2, - "NA", - "NA", - "NA" - ] - }, - "WT": { - "HLA-B*82:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" - ] - } - }, - "individual_percentile_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC", - "MHCflurryEL Presentation", - "NetMHCpanEL" - ], - "MT": { - "HLA-B*82:02": [ - 0.6832500100135803, - 0.18000000715255737, - "NA", - 0.5799999833106995, - 0.5, - 0.6000000238418579, - "NA", - "NA", - 9.15535326086956, - 1.2 - ] - }, - "WT": { - "HLA-B*82:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" - ] - } - }, - "wt_peptide": "FS-NA" - }, - "LPVPLLRLPA": { - "ic50s_MT": [ - "X", - "X", - 1177.0, - "X" - ], - "percentiles_MT": [ - "X", - "X", - 1.2000000476837158, - "X" - ], - "ic50s_WT": [ - "X", - "X", - "NA", - "X" - ], - "percentiles_WT": [ - "X", - "X", - "NA", - "X" - ], - "hla_types": [ - "HLA-A*29:02", - "HLA-B*45:01", - "HLA-B*82:02", - "HLA-C*06:02" - ], - "mutation_position": "NA", - "problematic_positions": "None", - "anchor_fails": "None", - "individual_ic50_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC" - ], - "MT": { - "HLA-B*82:02": [ - 2191.570832864349, - 727.88, - "NA", - 1177.0, - 2506.24, - 912.75, - "NA", - "NA" - ] - }, - "WT": { - "HLA-B*82:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" - ] - } - }, - "individual_ic50_percentile_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC" - ], - "MT": { - "HLA-B*82:02": [ - 0.4284999966621399, - 1.840000033378601, - "NA", - 0.699999988079071, - 0.25, - 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"NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC", - "MHCflurryEL Presentation", - "NetMHCpanEL" - ], - "MT": { - "HLA-B*82:02": [ - 0.4284999966621399, - 1.840000033378601, - "NA", - 0.699999988079071, - 0.25, - 1.2000000476837158, - "NA", - "NA", - 3.358777173912955, - 2.4 - ] - }, - "WT": { - "HLA-B*82:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" - ] - } - }, - "wt_peptide": "FS-NA" - } - }, - "transcripts": [ - "ENST00000531499.2-GPR68-NSSMSCT/X-8-14" - ], - "transcript_expr": [ - 0.047 - ], - "mane_select": [ - false - ], - "canonical": [ - false - ], - "tsl": [ - 1 - ], - "biotype": [ - "protein_coding" - ], - "transcript_cds_flags": [ - "None" - ], - "transcript_length": [ - 365 - ], - "transcript_count": 1, - "peptide_count": 13, - "total_expr": 0.047 - }, - "Transcript Set 2": { - "peptides": { - "LPGQLPVPL": { + "LPADQGPERAG": { "ic50s_MT": [ "X", "X", - 158.55999755859375, + 3766.31005859375, "X" ], "percentiles_MT": [ "X", "X", - 0.07999999821186066, + 5.671999931335449, "X" ], "ic50s_WT": [ @@ -117925,12 +117684,12 @@ ], "MT": { "HLA-B*82:02": [ - 121.71276475922818, - 158.56, + 2119.013329147795, + 7662.35, "NA", - 263.01, - 576.13, - 101.5, + 3766.31, + 26605.88, + 1376.93, "NA", "NA" ] @@ -117961,12 +117720,12 @@ ], "MT": { "HLA-B*82:02": [ - 0.010999999940395355, - 0.5699999928474426, + 0.4193750023841858, + 8.699999809265137, "NA", - 0.07999999821186066, - 0.03999999910593033, - 0.20000000298023224, + 2.5, + 17.0, + 2.0, "NA", "NA" ] @@ -117995,11 +117754,11 @@ ], "MT": { "HLA-B*82:02": [ - 0.0534636205411516, - 0.4623125207384621, - 0.491, - 0.010877984, - 0.0064323805, + 0.012543556469609, + 0.0443188671006861, + 0.0106, + 0.0007284336, + 0.0012529531, "NA" ] }, @@ -118026,8 +117785,8 @@ "MT": { "HLA-B*82:02": [ "NA", - 0.9059239130433668, - 0.05, + 5.671874999999957, + 6.5, "NA", "NA", "NA" @@ -118059,16 +117818,16 @@ ], "MT": { "HLA-B*82:02": [ - 0.010999999940395355, - 0.5699999928474426, + 0.4193750023841858, + 8.699999809265137, "NA", - 0.07999999821186066, - 0.03999999910593033, - 0.20000000298023224, + 2.5, + 17.0, + 2.0, "NA", "NA", - 0.9059239130433668, - 0.05 + 5.671874999999957, + 6.5 ] }, "WT": { @@ -118088,18 +117847,18 @@ }, "wt_peptide": "FS-NA" }, - "VRHPPVREH": { + "RRRQRGHL": { "ic50s_MT": [ "X", "X", "X", - 381.406005859375 + 3821.760009765625 ], "percentiles_MT": [ "X", "X", "X", - 0.6000000238418579 + 3.0 ], "ic50s_WT": [ "X", @@ -118135,228 +117894,18 @@ ], "MT": { "HLA-C*06:02": [ - 164.27231850781482, - 8177.5, - 107.27, - 652.65, - 3107.46, - 598.54, - 3.46, - 17.32 - ] - }, - "WT": { - "HLA-C*06:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" - ] - } - }, - "individual_ic50_percentile_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC" - ], - "MT": { - "HLA-C*06:02": [ - 0.6056249737739563, - 16.790000915527344, - 0.05999999865889549, - 0.800000011920929, - 0.699999988079071, - 0.699999988079071, - 0.2, - 0.4 - ] - }, - "WT": { - "HLA-C*06:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" - ] - } - }, - "individual_el_calls": { - "algorithms": [ - "MHCflurryEL Processing", - "MHCflurryEL Presentation", - "NetMHCpanEL", - "BigMHC_EL", - "BigMHC_IM", - "DeepImmuno" - ], - "MT": { - "HLA-C*06:02": [ - 0.3058738621184602, - 0.6108180467426889, - 0.398, - 0.40123963, - 0.19346094, - 0.9974298 - ] - }, - "WT": { - "HLA-C*06:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" - ] - } - }, - "individual_el_percentile_calls": { - "algorithms": [ - "MHCflurryEL Processing", - "MHCflurryEL Presentation", - "NetMHCpanEL", - "BigMHC_EL", - "BigMHC_IM", - "DeepImmuno" - ], - "MT": { - "HLA-C*06:02": [ - "NA", - 0.594076086956477, - 0.1, - "NA", - "NA", - "NA" - ] - }, - "WT": { - "HLA-C*06:02": [ - "NA", - "NA", - "NA", - "NA", + 5849.417759412565, + 5675.73, + 1820.27, + 268.76, + 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"problematic_positions": "None", - "anchor_fails": "None", - "individual_ic50_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC" - ], - "MT": { - "HLA-B*82:02": [ - 631.8167364745673, - 55.16, - "NA", - 407.64, - 664.53, - 340.99, - "NA", - "NA" - ] - }, - "WT": { - "HLA-B*82:02": [ "NA", "NA", "NA", @@ -118369,180 +117918,6 @@ } }, "individual_ic50_percentile_calls": { - "algorithms": [ - "MHCflurry", - "MHCnuggetsI", - "NetMHC", - "NetMHCcons", - "NetMHCpan", - "PickPocket", - "SMM", - "SMMPMBEC" - ], - "MT": { - "HLA-B*82:02": [ - 0.16737499833106995, - 0.17000000178813934, - "NA", - 0.05999999865889549, - 0.05000000074505806, - 0.30000001192092896, - "NA", - "NA" - ] - }, - "WT": { - "HLA-B*82:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" - ] - } - }, - "individual_el_calls": { - "algorithms": [ - "MHCflurryEL Processing", - "MHCflurryEL Presentation", - "NetMHCpanEL", 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+ "tsl": [ + 1 + ], + "biotype": [ + "protein_coding" + ], + "transcript_cds_flags": [ + "None" + ], + "transcript_length": [ + 338 + ], + "transcript_count": 1, + "peptide_count": 15, + "total_expr": 0.03 + }, + "Transcript Set 2": { + "peptides": { + "VRAAARQLV": { "ic50s_MT": [ "X", "X", - 707.8200073242188, - "X" + "X", + 73.3759994506836 ], "percentiles_MT": [ "X", "X", - 0.39399999380111694, - "X" + "X", + 0.20600000023841858 ], "ic50s_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "percentiles_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "hla_types": [ "HLA-A*29:02", @@ -120685,19 +118344,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 1957.8173238283944, - 351.21, - "NA", - 707.82, - 5294.62, - 274.64, - "NA", - "NA" + "HLA-C*06:02": [ + 80.54191241815123, + 1907.47, + 66.21, + 65.13, + 87.2, + 598.54, + 6.96, + 16.81 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -120721,19 +118380,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 0.3936249911785126, - 1.100000023841858, - "NA", - 0.28999999165534973, + "HLA-C*06:02": [ + 0.21199999749660492, + 6.190000057220459, + 0.03999999910593033, + 0.07000000029802322, + 0.029999999329447746, 0.699999988079071, - 0.20000000298023224, - "NA", - "NA" + 0.2, + 0.3 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -120755,17 +118414,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.3335151067003608, - 0.1348755160413384, - 0.298, - 0.0056533404, - 0.013133028, - "NA" + "HLA-C*06:02": [ + 0.062681098235771, + 0.5701920064261696, + 0.512, + 0.30477586, + 0.21663876, + 0.8201146 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -120785,17 +118444,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", - 2.390326086956435, - 0.15, + 0.6757880434782066, + 0.05, "NA", "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -120819,21 +118478,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-B*82:02": [ - 0.3936249911785126, - 1.100000023841858, - "NA", - 0.28999999165534973, + "HLA-C*06:02": [ + 0.21199999749660492, + 6.190000057220459, + 0.03999999910593033, + 0.07000000029802322, + 0.029999999329447746, 0.699999988079071, - 0.20000000298023224, - "NA", - "NA", - 2.390326086956435, - 0.15 + 0.2, + 0.3, + 0.6757880434782066, + 0.05 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -120849,17 +118508,17 @@ }, "wt_peptide": "FS-NA" }, - "GPERAGRVPV": { + "GPSLPLPPV": { "ic50s_MT": [ "X", "X", - 1006.0999755859375, + 335.4670104980469, "X" ], "percentiles_MT": [ "X", "X", - 0.6000000238418579, + 0.4000000059604645, "X" ], "ic50s_WT": [ @@ -120896,12 +118555,12 @@ ], "MT": { "HLA-B*82:02": [ - 4311.272782289639, - 56.66, + 335.4672341488855, + 238.42, "NA", - 1006.1, - 4159.16, - 525.66, + 814.73, + 1907.0, + 196.38, "NA", "NA" ] @@ -120932,12 +118591,12 @@ ], "MT": { "HLA-B*82:02": [ - 0.6832500100135803, - 0.18000000715255737, + 0.08487500250339508, + 0.8100000023841858, "NA", - 0.5799999833106995, - 0.5, - 0.6000000238418579, + 0.7400000095367432, + 0.17000000178813934, + 0.4000000059604645, "NA", "NA" ] @@ -120966,11 +118625,11 @@ ], "MT": { "HLA-B*82:02": [ - 0.0582541128387674, - 0.0266172137508801, - 0.0771, - 0.0019489471, - 0.00092341565, + 0.0222264141921186, + 0.223328403982173, + 0.296, + 0.029245984, + 0.004468919, "NA" ] }, @@ -120997,8 +118656,8 @@ "MT": { "HLA-B*82:02": [ "NA", - 9.15535326086956, - 1.2, + 1.6983695652173054, + 0.16, "NA", "NA", "NA" @@ -121030,16 +118689,16 @@ ], "MT": { "HLA-B*82:02": [ - 0.6832500100135803, - 0.18000000715255737, + 0.08487500250339508, + 0.8100000023841858, "NA", - 0.5799999833106995, - 0.5, - 0.6000000238418579, + 0.7400000095367432, + 0.17000000178813934, + 0.4000000059604645, "NA", "NA", - 9.15535326086956, - 1.2 + 1.6983695652173054, + 0.16 ] }, "WT": { @@ -121058,62 +118717,31 @@ } }, "wt_peptide": "FS-NA" - } - }, - "transcripts": [ - "ENST00000650645.1-GPR68-NSSMSCT/X-8-14" - ], - "transcript_expr": [ - 0.0 - ], - "mane_select": [ - true - ], - "canonical": [ - true - ], - "tsl": [ - "NA" - ], - "biotype": [ - "protein_coding" - ], - "transcript_cds_flags": [ - "None" - ], - "transcript_length": [ - 365 - ], - "transcript_count": 1, - "peptide_count": 6, - "total_expr": 0.0 - }, - "Transcript Set 4": { - "peptides": { - "VRAAARQLV": { + }, + "LPGVRHPPV": { "ic50s_MT": [ "X", "X", - "X", - 73.3759994506836 + 367.38299560546875, + "X" ], "percentiles_MT": [ "X", "X", - "X", - 0.20600000023841858 + 0.3100000023841858, + "X" ], "ic50s_WT": [ "X", "X", - "X", - "NA" + "NA", + "X" ], "percentiles_WT": [ "X", "X", - "X", - "NA" + "NA", + "X" ], "hla_types": [ "HLA-A*29:02", @@ -121136,19 +118764,19 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 80.54191241815123, - 1907.47, - 66.21, - 65.13, - 87.2, - 598.54, - 6.96, - 16.81 + "HLA-B*82:02": [ + 367.3827758769957, + 56.38, + "NA", + 503.39, + 956.77, + 263.01, + "NA", + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -121172,19 +118800,19 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 0.21199999749660492, - 6.190000057220459, - 0.03999999910593033, - 0.07000000029802322, - 0.029999999329447746, + "HLA-B*82:02": [ + 0.09437499940395355, + 0.18000000715255737, + "NA", + 0.3100000023841858, + 0.07999999821186066, 0.699999988079071, - 0.2, - 0.3 + "NA", + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -121206,17 +118834,17 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ - 0.062681098235771, - 0.5701920064261696, - 0.512, - 0.30477586, - 0.21663876, - 0.8201146 + "HLA-B*82:02": [ + 0.0440800187643617, + 0.2214338679591464, + 0.205, + 0.0034731566, + 0.012823993, + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -121236,17 +118864,17 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", - 0.6757880434782066, - 0.05, + 1.7091576086955769, + 0.32, "NA", "NA", "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -121270,21 +118898,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-C*06:02": [ - 0.21199999749660492, - 6.190000057220459, - 0.03999999910593033, - 0.07000000029802322, - 0.029999999329447746, + "HLA-B*82:02": [ + 0.09437499940395355, + 0.18000000715255737, + "NA", + 0.3100000023841858, + 0.07999999821186066, 0.699999988079071, - 0.2, - 0.3, - 0.6757880434782066, - 0.05 + "NA", + "NA", + 1.7091576086955769, + 0.32 ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -121300,30 +118928,30 @@ }, "wt_peptide": "FS-NA" }, - "LPGQLPVPL": { + "GREPAPRVL": { "ic50s_MT": [ "X", "X", - 158.55999755859375, - "X" + "X", + 526.875 ], "percentiles_MT": [ "X", "X", - 0.07999999821186066, - "X" + "X", + 0.5249999761581421 ], "ic50s_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "percentiles_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "hla_types": [ "HLA-A*29:02", @@ -121346,19 +118974,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 121.71276475922818, - 158.56, - "NA", - 263.01, - 576.13, - 101.5, - "NA", - "NA" + "HLA-C*06:02": [ + 83.763930129218, + 24949.85, + 648.43, + 461.65, + 1895.79, + 592.1, + 48.96, + 80.46 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121382,19 +119010,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 0.010999999940395355, - 0.5699999928474426, - "NA", - 0.07999999821186066, - 0.03999999910593033, - 0.20000000298023224, - "NA", - "NA" + "HLA-C*06:02": [ + 0.22762499749660492, + 47.470001220703125, + 0.23999999463558197, + 0.6299999952316284, + 0.41999998688697815, + 0.699999988079071, + 0.9, + 1.3 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121416,17 +119044,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.0534636205411516, - 0.4623125207384621, - 0.491, - 0.010877984, - 0.0064323805, - "NA" + "HLA-C*06:02": [ + 0.4152056146413088, + 0.8163499110383341, + 0.464, + 0.26677617, + 0.0141969025, + 0.97908276 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121446,17 +119074,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", - 0.9059239130433668, - 0.05, + 0.2525815217391169, + 0.06, "NA", "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121480,21 +119108,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-B*82:02": [ - 0.010999999940395355, - 0.5699999928474426, - "NA", - 0.07999999821186066, - 0.03999999910593033, - 0.20000000298023224, - "NA", - "NA", - 0.9059239130433668, - 0.05 + "HLA-C*06:02": [ + 0.22762499749660492, + 47.470001220703125, + 0.23999999463558197, + 0.6299999952316284, + 0.41999998688697815, + 0.699999988079071, + 0.9, + 1.3, + 0.2525815217391169, + 0.06 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121510,17 +119138,17 @@ }, "wt_peptide": "FS-NA" }, - "GPSLPLPPV": { + "VPVQPDGGRPL": { "ic50s_MT": [ "X", "X", - 335.4670104980469, + 876.030029296875, "X" ], "percentiles_MT": [ "X", "X", - 0.4000000059604645, + 0.5, "X" ], "ic50s_WT": [ @@ -121557,12 +119185,12 @@ ], "MT": { "HLA-B*82:02": [ - 335.4672341488855, - 238.42, + 112.60430901677472, + 876.03, "NA", - 814.73, - 1907.0, - 196.38, + 1006.1, + 4178.92, + 492.62, "NA", "NA" ] @@ -121593,12 +119221,12 @@ ], "MT": { "HLA-B*82:02": [ - 0.08487500250339508, - 0.8100000023841858, + 0.008750000037252903, + 2.0899999141693115, "NA", - 0.7400000095367432, - 0.17000000178813934, - 0.4000000059604645, + 0.5299999713897705, + 0.5, + 0.5, "NA", "NA" ] @@ -121627,11 +119255,11 @@ ], "MT": { "HLA-B*82:02": [ - 0.0222264141921186, - 0.223328403982173, - 0.296, - 0.029245984, - 0.004468919, + 0.3753255642950535, + 0.743322291249028, + 0.251, + 0.08228921, + 0.04480669, "NA" ] }, @@ -121658,8 +119286,8 @@ "MT": { "HLA-B*82:02": [ "NA", - 1.6983695652173054, - 0.16, + 0.3685326086956451, + 0.22, "NA", "NA", "NA" @@ -121691,16 +119319,16 @@ ], "MT": { "HLA-B*82:02": [ - 0.08487500250339508, - 0.8100000023841858, + 0.008750000037252903, + 2.0899999141693115, "NA", - 0.7400000095367432, - 0.17000000178813934, - 0.4000000059604645, + 0.5299999713897705, + 0.5, + 0.5, "NA", "NA", - 1.6983695652173054, - 0.16 + 0.3685326086956451, + 0.22 ] }, "WT": { @@ -121720,30 +119348,30 @@ }, "wt_peptide": "FS-NA" }, - "LPGVRHPPV": { + "YRAGGGLPGQL": { "ic50s_MT": [ "X", "X", - 367.38299560546875, - "X" + "X", + 915.7150268554688 ], "percentiles_MT": [ "X", "X", - 0.3100000023841858, - "X" + "X", + 0.5789999961853027 ], "ic50s_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "percentiles_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "hla_types": [ "HLA-A*29:02", @@ -121766,19 +119394,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 367.3827758769957, - 56.38, - "NA", - 503.39, - 956.77, - 263.01, + "HLA-C*06:02": [ + 103.5873091078729, + 297.87, + 19114.51, + 282.17, + 1533.56, + 3766.31, "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121802,19 +119430,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 0.09437499940395355, - 0.18000000715255737, - "NA", - 0.3100000023841858, - 0.07999999821186066, - 0.699999988079071, + "HLA-C*06:02": [ + 0.3345000147819519, + 1.9199999570846558, + 8.100000381469727, + 0.3400000035762787, + 0.3400000035762787, + 2.799999952316284, "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121836,17 +119464,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.0440800187643617, - 0.2214338679591464, - 0.205, - 0.0034731566, - 0.012823993, + "HLA-C*06:02": [ + 0.0533772714552469, + 0.5013219711890021, + 0.192, + 0.09358336, + 0.033584353, "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121866,17 +119494,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", - 1.7091576086955769, - 0.32, + 0.8186141304346393, + 0.29, "NA", "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121900,21 +119528,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-B*82:02": [ - 0.09437499940395355, - 0.18000000715255737, - "NA", - 0.3100000023841858, - 0.07999999821186066, - 0.699999988079071, + "HLA-C*06:02": [ + 0.3345000147819519, + 1.9199999570846558, + 8.100000381469727, + 0.3400000035762787, + 0.3400000035762787, + 2.799999952316284, "NA", "NA", - 1.7091576086955769, - 0.32 + 0.8186141304346393, + 0.29 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -121930,30 +119558,30 @@ }, "wt_peptide": "FS-NA" }, - "VRHPPVREH": { + "LPVPLLRLPA": { "ic50s_MT": [ "X", "X", - "X", - 381.406005859375 + 1177.0, + "X" ], "percentiles_MT": [ "X", "X", - "X", - 0.6000000238418579 + 1.2000000476837158, + "X" ], "ic50s_WT": [ "X", "X", - "X", - "NA" + "NA", + "X" ], "percentiles_WT": [ "X", "X", - "X", - "NA" + "NA", + "X" ], "hla_types": [ "HLA-A*29:02", @@ -121976,19 +119604,19 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 164.27231850781482, - 8177.5, - 107.27, - 652.65, - 3107.46, - 598.54, - 3.46, - 17.32 + "HLA-B*82:02": [ + 2191.570832864349, + 727.88, + "NA", + 1177.0, + 2506.24, + 912.75, + "NA", + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -122012,19 +119640,19 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 0.6056249737739563, - 16.790000915527344, - 0.05999999865889549, - 0.800000011920929, - 0.699999988079071, + "HLA-B*82:02": [ + 0.4284999966621399, + 1.840000033378601, + "NA", 0.699999988079071, - 0.2, - 0.4 + 0.25, + 1.2000000476837158, + "NA", + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -122046,17 +119674,17 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ - 0.3058738621184602, - 0.6108180467426889, - 0.398, - 0.40123963, - 0.19346094, - 0.9974298 + "HLA-B*82:02": [ + 0.2074727965518832, + 0.0821088906011905, + 0.0386, + 0.00073456543, + 0.0044832644, + "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -122076,17 +119704,17 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", - 0.594076086956477, - 0.1, + 3.358777173912955, + 2.4, "NA", "NA", "NA" ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -122110,21 +119738,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-C*06:02": [ - 0.6056249737739563, - 16.790000915527344, - 0.05999999865889549, - 0.800000011920929, - 0.699999988079071, + "HLA-B*82:02": [ + 0.4284999966621399, + 1.840000033378601, + "NA", 0.699999988079071, - 0.2, - 0.4, - 0.594076086956477, - 0.1 + 0.25, + 1.2000000476837158, + "NA", + "NA", + 3.358777173912955, + 2.4 ] }, "WT": { - "HLA-C*06:02": [ + "HLA-B*82:02": [ "NA", "NA", "NA", @@ -122140,29 +119768,29 @@ }, "wt_peptide": "FS-NA" }, - "RPLLHLLAAL": { + "REHLHQRGL": { "ic50s_MT": [ "X", + 2246.43994140625, "X", - 407.6400146484375, "X" ], "percentiles_MT": [ "X", + 2.299999952316284, "X", - 0.17000000178813934, "X" ], "ic50s_WT": [ - "X", "X", "NA", + "X", "X" ], "percentiles_WT": [ - "X", "X", "NA", + "X", "X" ], "hla_types": [ @@ -122186,19 +119814,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 631.8167364745673, - 55.16, - "NA", - 407.64, - 664.53, - 340.99, - "NA", - "NA" + "HLA-B*45:01": [ + 270.3844260036878, + 12950.92, + 5474.22, + 2240.61, + 2607.94, + 598.54, + 1955.28, + 2252.27 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -122222,19 +119850,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 0.16737499833106995, - 0.17000000178813934, - "NA", - 0.05999999865889549, - 0.05000000074505806, - 0.30000001192092896, - "NA", - "NA" + "HLA-B*45:01": [ + 0.6014999747276306, + 13.449999809265137, + 4.5, + 2.799999952316284, + 1.2999999523162842, + 1.7999999523162842, + 7.4, + 8.4 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -122256,17 +119884,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.0690833257976919, - 0.1550502404555942, - 0.221, - 0.0012070949, - 0.018217355, + "HLA-B*45:01": [ + 0.2766908211633563, + 0.4659166337418926, + 0.249, + 0.013763225, + 0.003112162, "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -122286,17 +119914,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", - 2.1829619565216376, - 0.28, + 0.897010869565122, + 0.47, "NA", "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -122320,21 +119948,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-B*82:02": [ - 0.16737499833106995, - 0.17000000178813934, - "NA", - 0.05999999865889549, - 0.05000000074505806, - 0.30000001192092896, - "NA", - "NA", - 2.1829619565216376, - 0.28 + "HLA-B*45:01": [ + 0.6014999747276306, + 13.449999809265137, + 4.5, + 2.799999952316284, + 1.2999999523162842, + 1.7999999523162842, + 7.4, + 8.4, + 0.897010869565122, + 0.47 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -122350,30 +119978,30 @@ }, "wt_peptide": "FS-NA" }, - "GREPAPRVL": { + "ITADHRPY": { "ic50s_MT": [ + 3357.68505859375, "X", "X", - "X", - 526.875 + "X" ], "percentiles_MT": [ + 1.9210000038146973, "X", "X", - "X", - 0.5249999761581421 + "X" ], "ic50s_WT": [ + 27477.815, "X", "X", - "X", - "NA" + "X" ], "percentiles_WT": [ + 29.446, "X", "X", - "X", - "NA" + "X" ], "hla_types": [ "HLA-A*29:02", @@ -122381,7 +120009,7 @@ "HLA-B*82:02", "HLA-C*06:02" ], - "mutation_position": "NA", + "mutation_position": "5, 6, 7, 8", "problematic_positions": "None", "anchor_fails": "None", "individual_ic50_calls": { @@ -122396,27 +120024,27 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 83.763930129218, - 24949.85, - 648.43, - 461.65, - 1895.79, - 592.1, - 48.96, - 80.46 + "HLA-A*29:02": [ + 673.3450036243738, + 4616.14, + 1728.48, + 21.84, + 5464.69, + 2443.19, + 4272.18, + 13550.33 ] }, "WT": { - "HLA-C*06:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" + "HLA-A*29:02": [ + 28523.049407326296, + 5812.71, + 26432.58, + 3219.45, + 32038.23, + 8664.37, + 33239.16, + 33415.66 ] } }, @@ -122432,27 +120060,27 @@ "SMMPMBEC" ], "MT": { - "HLA-C*06:02": [ - 0.22762499749660492, - 47.470001220703125, - 0.23999999463558197, - 0.6299999952316284, - 0.41999998688697815, - 0.699999988079071, - 0.9, - 1.3 + "HLA-A*29:02": [ + 1.4302500486373901, + 1.4199999570846558, + 2.299999952316284, + 0.28999999165534973, + 3.0999999046325684, + 0.8999999761581421, + 2.6, + 13.0 ] }, "WT": { - "HLA-C*06:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" + "HLA-A*29:02": [ + 30.891874999999995, + 21.32, + 28.0, + 4.1, + 35.0, + 7.8, + 34.0, + 34.0 ] } }, @@ -122466,22 +120094,22 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ - 0.4152056146413088, - 0.8163499110383341, - 0.464, - 0.26677617, - 0.0141969025, - 0.97908276 + "HLA-A*29:02": [ + 0.0735752977197989, + 0.1491263588885815, + 0.0424, + 0.3372477, + 0.78433836, + "NA" ] }, "WT": { - "HLA-C*06:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", + "HLA-A*29:02": [ + 0.0091054324439028, + 0.0036532959116699, + 0.000611, + 0.001756957, + 0.07034252, "NA" ] } @@ -122496,20 +120124,20 @@ "DeepImmuno" ], "MT": { - "HLA-C*06:02": [ + "HLA-A*29:02": [ "NA", - 0.2525815217391169, - 0.06, + 2.241521739130363, + 1.6, "NA", "NA", "NA" ] }, "WT": { - "HLA-C*06:02": [ - "NA", - "NA", + "HLA-A*29:02": [ "NA", + 99.28660326086955, + 12.0, "NA", "NA", "NA" @@ -122530,60 +120158,60 @@ "NetMHCpanEL" ], "MT": { - "HLA-C*06:02": [ - 0.22762499749660492, - 47.470001220703125, - 0.23999999463558197, - 0.6299999952316284, - 0.41999998688697815, - 0.699999988079071, - 0.9, - 1.3, - 0.2525815217391169, - 0.06 + "HLA-A*29:02": [ + 1.4302500486373901, + 1.4199999570846558, + 2.299999952316284, + 0.28999999165534973, + 3.0999999046325684, + 0.8999999761581421, + 2.6, + 13.0, + 2.241521739130363, + 1.6 ] }, "WT": { - "HLA-C*06:02": [ - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA", - "NA" + "HLA-A*29:02": [ + 30.891874999999995, + 21.32, + 28.0, + 4.1, + 35.0, + 7.8, + 34.0, + 34.0, + 99.28660326086955, + 12.0 ] } }, - "wt_peptide": "FS-NA" + "wt_peptide": "ITADNSSM" }, - "VPVQPDGGRPL": { + "HRPYHPPDA": { "ic50s_MT": [ "X", "X", - 876.030029296875, - "X" + "X", + 3435.340087890625 ], "percentiles_MT": [ "X", "X", - 0.5, - "X" + "X", + 2.4240000247955322 ], "ic50s_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "percentiles_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "hla_types": [ "HLA-A*29:02", @@ -122606,19 +120234,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 112.60430901677472, - 876.03, - "NA", - 1006.1, - 4178.92, - 492.62, - "NA", - "NA" + "HLA-C*06:02": [ + 835.7107258862588, + 30810.4, + 5777.83, + 8387.64, + 5580.3, + 1290.38, + 140.22, + 177.24 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -122642,19 +120270,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 0.008750000037252903, - 2.0899999141693115, - "NA", - 0.5299999713897705, - 0.5, - 0.5, - "NA", - "NA" + "HLA-C*06:02": [ + 2.448499917984009, + 61.81999969482422, + 2.0, + 7.900000095367432, + 1.5, + 2.4000000953674316, + 2.1, + 2.5 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -122676,17 +120304,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.3753255642950535, - 0.743322291249028, - 0.251, - 0.08228921, - 0.04480669, - "NA" + "HLA-C*06:02": [ + 0.0472138517070561, + 0.1146015804753184, + 0.0362, + 0.004055911, + 0.079072304, + 0.99789274 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -122706,17 +120334,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", - 0.3685326086956451, - 0.22, + 2.660624999999925, + 1.3, "NA", "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -122740,21 +120368,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-B*82:02": [ - 0.008750000037252903, - 2.0899999141693115, - "NA", - 0.5299999713897705, - 0.5, - 0.5, - "NA", - "NA", - 0.3685326086956451, - 0.22 + "HLA-C*06:02": [ + 2.448499917984009, + 61.81999969482422, + 2.0, + 7.900000095367432, + 1.5, + 2.4000000953674316, + 2.1, + 2.5, + 2.660624999999925, + 1.3 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -122770,18 +120398,18 @@ }, "wt_peptide": "FS-NA" }, - "YRAGGGLPGQL": { + "RRRQRGHL": { "ic50s_MT": [ "X", "X", "X", - 915.7150268554688 + 3821.760009765625 ], "percentiles_MT": [ "X", "X", "X", - 0.5789999961853027 + 3.0 ], "ic50s_WT": [ "X", @@ -122817,12 +120445,12 @@ ], "MT": { "HLA-C*06:02": [ - 103.5873091078729, - 297.87, - 19114.51, - 282.17, - 1533.56, - 3766.31, + 5849.417759412565, + 5675.73, + 1820.27, + 268.76, + 10967.88, + 1967.79, "NA", "NA" ] @@ -122853,12 +120481,12 @@ ], "MT": { "HLA-C*06:02": [ - 0.3345000147819519, - 1.9199999570846558, - 8.100000381469727, - 0.3400000035762787, - 0.3400000035762787, - 2.799999952316284, + 9.659375190734863, + 12.829999923706055, + 0.5600000023841858, + 0.25999999046325684, + 3.200000047683716, + 0.8999999761581421, "NA", "NA" ] @@ -122887,11 +120515,11 @@ ], "MT": { "HLA-C*06:02": [ - 0.0533772714552469, - 0.5013219711890021, - 0.192, - 0.09358336, - 0.033584353, + 0.0004953355146426, + 0.0163033673338569, + 0.00993, + 0.0003866035, + 0.009682626, "NA" ] }, @@ -122918,8 +120546,8 @@ "MT": { "HLA-C*06:02": [ "NA", - 0.8186141304346393, - 0.29, + 14.277038043478257, + 2.8, "NA", "NA", "NA" @@ -122951,16 +120579,16 @@ ], "MT": { "HLA-C*06:02": [ - 0.3345000147819519, - 1.9199999570846558, - 8.100000381469727, - 0.3400000035762787, - 0.3400000035762787, - 2.799999952316284, + 9.659375190734863, + 12.829999923706055, + 0.5600000023841858, + 0.25999999046325684, + 3.200000047683716, + 0.8999999761581421, "NA", "NA", - 0.8186141304346393, - 0.29 + 14.277038043478257, + 2.8 ] }, "WT": { @@ -122980,29 +120608,29 @@ }, "wt_peptide": "FS-NA" }, - "QPDGGRPLLHL": { + "PERAGRVPV": { "ic50s_MT": [ "X", + 3987.18896484375, "X", - 977.989990234375, "X" ], "percentiles_MT": [ "X", + 3.700000047683716, "X", - 0.800000011920929, "X" ], "ic50s_WT": [ - "X", "X", "NA", + "X", "X" ], "percentiles_WT": [ - "X", "X", "NA", + "X", "X" ], "hla_types": [ @@ -123026,19 +120654,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 640.1576087147172, - 977.99, - "NA", - 1229.06, - 6307.94, - 497.98, - "NA", - "NA" + "HLA-B*45:01": [ + 3889.698233791165, + 10082.68, + 4231.06, + 4084.68, + 8681.07, + 727.23, + 1052.47, + 1616.66 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -123062,19 +120690,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 0.16850000619888306, - 2.25, - "NA", - 0.800000011920929, - 0.9100000262260437, - 0.5, - "NA", - "NA" + "HLA-B*45:01": [ + 1.981124997138977, + 10.510000228881836, + 3.799999952316284, + 3.5999999046325684, + 3.299999952316284, + 2.299999952316284, + 4.0, + 6.2 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -123096,17 +120724,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.5303559824824333, - 0.4809529869101319, - 0.392, - 0.010950968, - 0.0039295745, + "HLA-B*45:01": [ + 0.0458754374994896, + 0.0281114864640976, + 0.0198, + 0.003418463, + 0.00036277887, "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -123126,17 +120754,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", - 0.8628804347825252, - 0.09, + 8.545326086956507, + 2.6, "NA", "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -123160,21 +120788,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-B*82:02": [ - 0.16850000619888306, - 2.25, - "NA", - 0.800000011920929, - 0.9100000262260437, - 0.5, - "NA", - "NA", - 0.8628804347825252, - 0.09 + "HLA-B*45:01": [ + 1.981124997138977, + 10.510000228881836, + 3.799999952316284, + 3.5999999046325684, + 3.299999952316284, + 2.299999952316284, + 4.0, + 6.2, + 8.545326086956507, + 2.6 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-B*45:01": [ "NA", "NA", "NA", @@ -123189,18 +120817,49 @@ } }, "wt_peptide": "FS-NA" - }, - "GPERAGRVPV": { + } + }, + "transcripts": [ + "ENST00000531499.2-GPR68-NSSMSCT/X-8-14" + ], + "transcript_expr": [ + 0.047 + ], + "mane_select": [ + false + ], + "canonical": [ + false + ], + "tsl": [ + 1 + ], + "biotype": [ + "protein_coding" + ], + "transcript_cds_flags": [ + "None" + ], + "transcript_length": [ + 365 + ], + "transcript_count": 1, + "peptide_count": 12, + "total_expr": 0.047 + }, + "Transcript Set 3": { + "peptides": { + "VPVQPDGGRPL": { "ic50s_MT": [ "X", "X", - 1006.0999755859375, + 876.030029296875, "X" ], "percentiles_MT": [ "X", "X", - 0.6000000238418579, + 0.5, "X" ], "ic50s_WT": [ @@ -123237,12 +120896,12 @@ ], "MT": { "HLA-B*82:02": [ - 4311.272782289639, - 56.66, + 112.60430901677472, + 876.03, "NA", 1006.1, - 4159.16, - 525.66, + 4178.92, + 492.62, "NA", "NA" ] @@ -123273,12 +120932,12 @@ ], "MT": { "HLA-B*82:02": [ - 0.6832500100135803, - 0.18000000715255737, + 0.008750000037252903, + 2.0899999141693115, "NA", - 0.5799999833106995, + 0.5299999713897705, + 0.5, 0.5, - 0.6000000238418579, "NA", "NA" ] @@ -123307,11 +120966,11 @@ ], "MT": { "HLA-B*82:02": [ - 0.0582541128387674, - 0.0266172137508801, - 0.0771, - 0.0019489471, - 0.00092341565, + 0.3753255642950535, + 0.743322291249028, + 0.251, + 0.08228921, + 0.04480669, "NA" ] }, @@ -123338,8 +120997,8 @@ "MT": { "HLA-B*82:02": [ "NA", - 9.15535326086956, - 1.2, + 0.3685326086956451, + 0.22, "NA", "NA", "NA" @@ -123371,16 +121030,16 @@ ], "MT": { "HLA-B*82:02": [ - 0.6832500100135803, - 0.18000000715255737, + 0.008750000037252903, + 2.0899999141693115, "NA", - 0.5799999833106995, + 0.5299999713897705, + 0.5, 0.5, - 0.6000000238418579, "NA", "NA", - 9.15535326086956, - 1.2 + 0.3685326086956451, + 0.22 ] }, "WT": { @@ -123400,30 +121059,30 @@ }, "wt_peptide": "FS-NA" }, - "RPLLHLLAALL": { + "YRAGGGLPGQL": { "ic50s_MT": [ "X", "X", - 1109.0, - "X" + "X", + 915.7150268554688 ], "percentiles_MT": [ "X", "X", - 0.800000011920929, - "X" + "X", + 0.5789999961853027 ], "ic50s_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "percentiles_WT": [ "X", "X", - "NA", - "X" + "X", + "NA" ], "hla_types": [ "HLA-A*29:02", @@ -123446,19 +121105,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 8796.947274506418, - 222.61, - "NA", - 1109.0, - 3400.51, - 611.63, + "HLA-C*06:02": [ + 103.5873091078729, + 297.87, + 19114.51, + 282.17, + 1533.56, + 3766.31, "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -123482,19 +121141,19 @@ "SMMPMBEC" ], "MT": { - "HLA-B*82:02": [ - 1.2139999866485596, - 0.7699999809265137, - "NA", - 0.699999988079071, - 0.3499999940395355, - 0.800000011920929, + "HLA-C*06:02": [ + 0.3345000147819519, + 1.9199999570846558, + 8.100000381469727, + 0.3400000035762787, + 0.3400000035762787, + 2.799999952316284, "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -123516,17 +121175,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ - 0.0339964970189612, - 0.0123974762130087, - 0.0858, - 0.00041599473, - 0.0054939394, + "HLA-C*06:02": [ + 0.0533772714552469, + 0.5013219711890021, + 0.192, + 0.09358336, + 0.033584353, "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -123546,17 +121205,17 @@ "DeepImmuno" ], "MT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", - 18.61798913043478, - 1.1, + 0.8186141304346393, + 0.29, "NA", "NA", "NA" ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -123580,21 +121239,21 @@ "NetMHCpanEL" ], "MT": { - "HLA-B*82:02": [ - 1.2139999866485596, - 0.7699999809265137, - "NA", - 0.699999988079071, - 0.3499999940395355, - 0.800000011920929, + "HLA-C*06:02": [ + 0.3345000147819519, + 1.9199999570846558, + 8.100000381469727, + 0.3400000035762787, + 0.3400000035762787, + 2.799999952316284, "NA", "NA", - 18.61798913043478, - 1.1 + 0.8186141304346393, + 0.29 ] }, "WT": { - "HLA-B*82:02": [ + "HLA-C*06:02": [ "NA", "NA", "NA", @@ -123822,10 +121481,10 @@ } }, "transcripts": [ - "ENST00000529102.1-GPR68-NSSMSCT/X-8-14" + "ENST00000535815.5-GPR68-NSSMSCT/X-8-14" ], "transcript_expr": [ - 0.03 + 0.0 ], "mane_select": [ false @@ -123843,36 +121502,32 @@ "None" ], "transcript_length": [ - 338 + 365 ], "transcript_count": 1, - "peptide_count": 13, - "total_expr": 0.03 + "peptide_count": 3, + "total_expr": 0.0 } }, "sets": [ "Transcript Set 1", "Transcript Set 2", - "Transcript Set 3", - "Transcript Set 4" + "Transcript Set 3" ], "transcript_counts": [ - 1, 1, 1, 1 ], "peptide_counts": [ - 13, - 9, - 6, - 13 + 15, + 12, + 3 ], "set_expr": [ + 0.03, 0.047, - 0.0, - 0.0, - 0.03 + 0.0 ], "DNA VAF": 0.093, "RNA VAF": 0.0, @@ -124758,9 +122413,9 @@ } }, "transcripts": [ - "ENST00000340892.9-TC2N-K/N-471", + "ENST00000435962.7-TC2N-K/N-471", "ENST00000360594.9-TC2N-K/N-471", - "ENST00000435962.7-TC2N-K/N-471" + "ENST00000340892.9-TC2N-K/N-471" ], "transcript_expr": [ 0.0, @@ -124768,19 +122423,19 @@ 0.0 ], "mane_select": [ + true, false, - false, - true + false ], "canonical": [ + true, false, - false, - true + false ], "tsl": [ + 2, 1, - 1, - 2 + 1 ], "biotype": [ "protein_coding", @@ -125496,16 +123151,16 @@ } }, "transcripts": [ - "ENST00000355814.8-SERPINA1-E/D-110" + "ENST00000393087.9-SERPINA1-E/D-110" ], "transcript_expr": [ 0.0 ], "mane_select": [ - false + true ], "canonical": [ - false + true ], "tsl": [ 1 @@ -126754,20 +124409,20 @@ } }, "transcripts": [ - "ENST00000346991.9-KNL1-P/S-865", - "ENST00000399668.7-KNL1-P/S-839" + "ENST00000399668.7-KNL1-P/S-839", + "ENST00000346991.9-KNL1-P/S-865" ], "transcript_expr": [ - 0.345, - 7.471 + 7.471, + 0.345 ], "mane_select": [ - false, - true + true, + false ], "canonical": [ - false, - true + true, + false ], "tsl": [ 1, @@ -126782,8 +124437,8 @@ "None" ], "transcript_length": [ - 2342, - 2316 + 2316, + 2342 ], "transcript_count": 2, "peptide_count": 1, @@ -127025,16 +124680,16 @@ } }, "transcripts": [ - "ENST00000346991.9-KNL1-P/L-865" + "ENST00000399668.7-KNL1-P/L-839" ], "transcript_expr": [ - 0.345 + 7.471 ], "mane_select": [ - false + true ], "canonical": [ - false + true ], "tsl": [ 1 @@ -127046,11 +124701,11 @@ "None" ], "transcript_length": [ - 2342 + 2316 ], "transcript_count": 1, "peptide_count": 1, - "total_expr": 0.345 + "total_expr": 7.471 } }, "sets": [ @@ -127063,7 +124718,7 @@ 1 ], "set_expr": [ - 0.345 + 7.471 ], "DNA VAF": 0.45, "RNA VAF": "NA", @@ -128625,20 +126280,20 @@ } }, "transcripts": [ - "ENST00000321429.8-DUOX1-R/K-43", - "ENST00000389037.7-DUOX1-R/K-43" + "ENST00000389037.7-DUOX1-R/K-43", + "ENST00000321429.8-DUOX1-R/K-43" ], "transcript_expr": [ 0.0, 0.0 ], "mane_select": [ - false, - true + true, + false ], "canonical": [ - false, - true + true, + false ], "tsl": [ 1, @@ -232482,7 +230137,7 @@ ], "DNA VAF": 0.65, "RNA VAF": 0.0, - "gene_expr": "NA", + "gene_expr": 0.0, "best_peptide_mt": "FRCDAATDV", "best_peptide_wt": "FRRDAATDV", "best_hla_allele": "HLA-C*06:02" @@ -233649,16 +231304,16 @@ } }, "transcripts": [ - "ENST00000246043.8-RRBP1-E/K-393" + "ENST00000377813.6-RRBP1-E/K-393" ], "transcript_expr": [ - 73.575 + 33.598 ], "mane_select": [ - false + true ], "canonical": [ - false + true ], "tsl": [ 1 @@ -233674,7 +231329,7 @@ ], "transcript_count": 1, "peptide_count": 1, - "total_expr": 73.575 + "total_expr": 33.598 } }, "sets": [ @@ -233687,7 +231342,7 @@ 1 ], "set_expr": [ - 73.575 + 33.598 ], "DNA VAF": 0.574, "RNA VAF": 0.493, @@ -248157,20 +245812,20 @@ } }, "transcripts": [ - "ENST00000381756.9-GGA1-P/A-501", - "ENST00000343632.9-GGA1-P/A-484" + "ENST00000343632.9-GGA1-P/A-484", + "ENST00000381756.9-GGA1-P/A-501" ], "transcript_expr": [ - 1.209, - 23.223 + 23.223, + 1.209 ], "mane_select": [ - false, - true + true, + false ], "canonical": [ - false, - true + true, + false ], "tsl": [ 1, @@ -248185,8 +245840,8 @@ "None" ], "transcript_length": [ - 656, - 639 + 639, + 656 ], "transcript_count": 2, "peptide_count": 1, @@ -276969,24 +274624,24 @@ } }, "transcripts": [ - "ENST00000426955.6-VWA5B2-A/V-836", - "ENST00000691901.1-VWA5B2-A/V-836" + "ENST00000691901.1-VWA5B2-A/V-836", + "ENST00000426955.6-VWA5B2-A/V-836" ], "transcript_expr": [ - 0.0, - 0.007 + 0.007, + 0.0 ], "mane_select": [ - false, - true + true, + false ], "canonical": [ - false, - true + true, + false ], "tsl": [ - 1, - "NA" + "NA", + 1 ], "biotype": [ "protein_coding", @@ -279377,12 +277032,12 @@ } }, "transcripts": [ - "ENST00000512093.5-SLAIN2-R/G-366", - "ENST00000510595.1-SLAIN2-R/G-142" + "ENST00000510595.1-SLAIN2-R/G-142", + "ENST00000512093.5-SLAIN2-R/G-366" ], "transcript_expr": [ - 9.72, - 5.579 + 5.579, + 9.72 ], "mane_select": [ false, @@ -279393,8 +277048,8 @@ false ], "tsl": [ - 5, - 4 + 4, + 5 ], "biotype": [ "protein_coding", @@ -279405,8 +277060,8 @@ "None" ], "transcript_length": [ - 414, - 169 + 169, + 414 ], "transcript_count": 2, "peptide_count": 1, @@ -300930,13 +298585,13 @@ }, "transcripts": [ "ENST00000683046.1-PRELID2-C/R-99", - "ENST00000505416.5-PRELID2-C/R-99", - "ENST00000511435.1-PRELID2-C/R-99" + "ENST00000511435.1-PRELID2-C/R-99", + "ENST00000505416.5-PRELID2-C/R-99" ], "transcript_expr": [ 0.664, - 0.197, - 0.256 + 0.256, + 0.197 ], "mane_select": [ true, @@ -300950,8 +298605,8 @@ ], "tsl": [ "NA", - 3, - 2 + 2, + 3 ], "biotype": [ "protein_coding", @@ -300965,8 +298620,8 @@ ], "transcript_length": [ 177, - 177, - 164 + 164, + 177 ], "transcript_count": 3, "peptide_count": 3, @@ -338002,12 +335657,12 @@ } }, "transcripts": [ - "ENST00000415482.6-PTPN12-H/Y-111", - "ENST00000435495.6-PTPN12-H/Y-100" + "ENST00000435495.6-PTPN12-H/Y-100", + "ENST00000415482.6-PTPN12-H/Y-111" ], "transcript_expr": [ - 46.053, - 35.285 + 35.285, + 46.053 ], "mane_select": [ false, @@ -338018,8 +335673,8 @@ false ], "tsl": [ - 5, - 2 + 2, + 5 ], "biotype": [ "protein_coding", @@ -338030,8 +335685,8 @@ "None" ], "transcript_length": [ - 661, - 650 + 650, + 661 ], "transcript_count": 2, "peptide_count": 2, @@ -362982,31 +360637,31 @@ } }, "transcripts": [ - "ENST00000425967.8-FGFR1-S/L-125", "ENST00000447712.7-FGFR1-S/L-125", + "ENST00000425967.8-FGFR1-S/L-125", "ENST00000397108.8-FGFR1-S/L-125", "ENST00000397113.6-FGFR1-S/L-125", "ENST00000525001.5-FGFR1-S/L-125" ], "transcript_expr": [ - 11.709, 0.008, + 11.709, 0.838, 0.145, 0.0 ], "mane_select": [ - false, true, false, false, + false, false ], "canonical": [ - false, true, false, false, + false, false ], "tsl": [ @@ -363031,8 +360686,8 @@ "None" ], "transcript_length": [ - 828, 822, + 828, 820, 820, 298 @@ -363255,18 +360910,18 @@ } }, "transcripts": [ - "ENST00000397103.5-FGFR1-S/L-36", + "ENST00000530568.5-FGFR1-S/L-36", "ENST00000526742.5-FGFR1-S/L-36", "ENST00000529552.5-FGFR1-S/L-36", - "ENST00000530568.5-FGFR1-S/L-36", - "ENST00000434187.5-FGFR1-S/L-36" + "ENST00000434187.5-FGFR1-S/L-36", + "ENST00000397103.5-FGFR1-S/L-36" ], "transcript_expr": [ - 5.622, + 2.767, 11.549, 0.539, - 2.767, - 0.719 + 0.719, + 5.622 ], "mane_select": [ false, @@ -363283,11 +360938,11 @@ false ], "tsl": [ - 5, + 3, 4, 4, - 3, - 4 + 4, + 5 ], "biotype": [ "protein_coding", @@ -363304,11 +360959,11 @@ "None" ], "transcript_length": [ - 733, + 85, 145, 142, - 85, - 54 + 54, + 733 ], "transcript_count": 5, "peptide_count": 1, @@ -364433,13 +362088,13 @@ } }, "transcripts": [ - "ENST00000396596.2-SGK3-A/V-92", "ENST00000519289.1-C8orf44-SGK3-A/V-92", + "ENST00000396596.2-SGK3-A/V-92", "ENST00000518388.5-SGK3-A/V-92" ], "transcript_expr": [ - 0.142, 0.338, + 0.142, 0.0 ], "mane_select": [ @@ -364448,13 +362103,13 @@ false ], "canonical": [ - false, true, + false, false ], "tsl": [ - 1, 2, + 1, 5 ], "biotype": [ @@ -365321,13 +362976,13 @@ }, "transcripts": [ "ENST00000521198.7-SGK3-A/V-92", - "ENST00000522398.5-SGK3-A/V-92", - "ENST00000521960.5-SGK3-A/V-25" + "ENST00000521960.5-SGK3-A/V-25", + "ENST00000522398.5-SGK3-A/V-92" ], "transcript_expr": [ 0.177, - 0.0, - 0.085 + 0.085, + 0.0 ], "mane_select": [ true, @@ -365341,8 +362996,8 @@ ], "tsl": [ 1, - 5, - 4 + 4, + 5 ], "biotype": [ "protein_coding", @@ -365356,8 +363011,8 @@ ], "transcript_length": [ 496, - 496, - 108 + 108, + 496 ], "transcript_count": 3, "peptide_count": 4, @@ -372444,8 +370099,8 @@ }, "transcripts": [ "ENST00000388996.10-KCNQ3-D/H-451", - "ENST00000519445.5-KCNQ3-D/H-451", - "ENST00000521134.6-KCNQ3-D/H-331" + "ENST00000521134.6-KCNQ3-D/H-331", + "ENST00000519445.5-KCNQ3-D/H-451" ], "transcript_expr": [ 0.0, @@ -372464,8 +370119,8 @@ ], "tsl": [ 1, - 5, - 2 + 2, + 5 ], "biotype": [ "protein_coding", @@ -372479,8 +370134,8 @@ ], "transcript_length": [ 872, - 860, - 752 + 752, + 860 ], "transcript_count": 3, "peptide_count": 2, @@ -400084,12 +397739,12 @@ } }, "transcripts": [ - "ENST00000642424.1-DDX3X-R/T-108", - "ENST00000646627.1-DDX3X-R/T-108" + "ENST00000646627.1-DDX3X-R/T-108", + "ENST00000642424.1-DDX3X-R/T-108" ], "transcript_expr": [ - 0.0, - 35.653 + 35.653, + 0.0 ], "mane_select": [ false, @@ -409580,14 +407235,14 @@ }, "transcripts": [ "ENST00000341514.11-ATP7A-D/H-870", - "ENST00000689767.1-ATP7A-D/H-901", "ENST00000343533.10-ATP7A-D/H-880", + "ENST00000689767.1-ATP7A-D/H-901", "ENST00000692908.1-ATP7A-D/H-792" ], "transcript_expr": [ 1.293, - 0.071, 0.114, + 0.071, 0.0 ], "mane_select": [ @@ -409604,8 +407259,8 @@ ], "tsl": [ 1, - "NA", 5, + "NA", "NA" ], "biotype": [ @@ -409622,8 +407277,8 @@ ], "transcript_length": [ 1500, - 1531, 1510, + 1531, 1422 ], "transcript_count": 4, diff --git a/tests/test_data/aggregate_all_epitopes/HCC1395.output.tsv b/tests/test_data/aggregate_all_epitopes/HCC1395.output.tsv index 4acc12355..b3250c2c1 100644 --- a/tests/test_data/aggregate_all_epitopes/HCC1395.output.tsv +++ b/tests/test_data/aggregate_all_epitopes/HCC1395.output.tsv @@ -15,14 +15,14 @@ chr10-37957500-37957501-C-T 576.ZNF25.ENST00000302609.8.missense.21E/K 1 ZNF2 chr13-113425167-113425168-G-T 725.ADPRHL1.ENST00000612156.3.missense.220H/N 1 ADPRHL1 H220N 4 HTAEYQENWFY ENST00000612156.3 True True 5 HLA-A*29:02 8 None 14 1 284.910 142.450 0.325 0.260 2.743 0.917 2.515 24.000 0.517 Pass Pending chrX-41344254-41344255-G-C 1051.DDX3X.ENST00000399959.7.missense.293R/T 1 2 DDX3X R293T 19 RKFSYRSTV ENST00000399959.7 False False 1 HLA-C*06:02 8 None 10 3 513.090 906.662 0.635 1.600 158.794 0.999 158.635 1381.000 0.966 PoorBinder Pending chr10-125859825-125859826-G-C 588.DHX32.ENST00000284690.4.missense.209P/R DHX32 P209R 1 ARRELKLII ENST00000284690.4 True True 1 HLA-C*06:02 3 None 3 0 507.740 530.850 0.462 0.925 53.951 0.998 53.843 518.000 1.000 PoorBinder Pending -chr12-889169-889170-C-G 673.WNK1.ENST00000530271.6.missense.2212Q/E WNK1 Q2212E 7 AELRRTLSP ENST00000530271.6 False False 1 HLA-B*45:01 2 None 5 0 630.500 9432.691 1.250 9.478 97.460 0.700 68.222 593.000 0.604 PoorBinder Pending +chr12-889169-889170-C-G 671.WNK1.ENST00000315939.11.missense.1799Q/E WNK1 Q1799E 7 AELRRTLSP ENST00000315939.11 True True 1 HLA-B*45:01 2 None 5 0 630.500 9432.691 1.250 9.478 97.460 0.700 68.222 593.000 0.604 PoorBinder Pending chrX-1419025-1419026-G-A 1030.ASMTL.ENST00000381317.9.missense.445T/M ASMTL T445M 3 AMAFNLSRF ENST00000381317.9 True True 1 HLA-A*29:02 2 None 4 0 618.761 2037.415 1.579 2.250 74.609 0.460 34.320 804.000 0.467 PoorBinder Pending chr18-36067341-36067342-C-G 904.RPRD1A.ENST00000399022.9.missense.21Q/H RPRD1A Q21H 2 SELSNSQHS ENST00000399022.9 True True 1 HLA-B*45:01 8 None 3 0 630.160 633.500 1.343 1.350 57.249 0.500 28.625 602.000 0.417 PoorBinder Pending chr3-121697676-121697677-G-C 231.GOLGB1.ENST00000614479.5.missense.949A/G GOLGB1 A949G 5 AEEGKKEQV ENST00000614479.5 True True 1 HLA-B*45:01 4 None 5 0 865.085 588.880 1.300 0.990 45.429 0.967 43.930 307.000 1.000 PoorBinder Pending -chr3-172353066-172353067-C-T 249.FNDC3B.ENST00000336824.8.missense.927P/S FNDC3B P927S 3 SETTYRIRIQA ENST00000336824.8 False False 1 HLA-B*45:01 1 None 5 0 776.075 10817.910 1.190 10.200 92.076 0.317 29.188 928.000 0.356 PoorBinder Pending +chr3-172353066-172353067-C-T 250.FNDC3B.ENST00000415807.7.missense.927P/S FNDC3B P927S 3 SETTYRIRIQA ENST00000415807.7 True True 1 HLA-B*45:01 1 None 5 0 776.075 10817.910 1.190 10.200 92.076 0.317 29.188 928.000 0.356 PoorBinder Pending chr2-47806319-47806320-G-A 123.MSH6.ENST00000614496.4.missense.953D/N 1 1 MSH6 D953N 6 VENYSQNVAV ENST00000614496.4 False False 1 HLA-B*45:01 3 None 7 2 525.565 1120.585 0.775 1.300 48.832 0.338 16.505 352.000 0.318 PoorBinder Pending chr5-134893641-134893642-T-C 302.TXNDC15.ENST00000358387.9.missense.248S/P TXNDC15 S248P 2 APQHSSLSTRF ENST00000358387.9 True True 1 HLA-B*82:02 2 None 3 0 1145.590 24218.040 1.000 23.590 42.950 0.996 42.778 447.000 0.993 PoorBinder Pending -chr1-36179727-36179728-G-A 18.MAP7D1.ENST00000373151.6.missense.765E/K MAP7D1 E765K 3 KPIPQEPQWSL ENST00000373151.6 False False 1 HLA-B*82:02 1 None 3 0 1091.150 733.791 0.670 0.300 93.193 0.326 30.381 1643.000 0.309 PoorBinder Pending +chr1-36179727-36179728-G-A 19.MAP7D1.ENST00000474796.2.missense.764E/K MAP7D1 E764K 3 KPIPQEPQWSL ENST00000474796.2 True True 2 HLA-B*82:02 1 None 3 0 1091.150 733.791 0.670 0.300 93.193 0.326 30.381 1643.000 0.309 PoorBinder Pending chrX-77681732-77681733-T-C 1088.ATRX.ENST00000373344.11.missense.1175K/E ATRX K1175E 4 SEKKAVIV ENST00000373344.11 True True 1 HLA-B*45:01 2 None 3 0 1330.390 29762.685 0.835 26.634 57.053 0.990 56.482 293.000 1.000 PoorBinder Pending chrX-40655057-40655058-G-T 1050.MED14.ENST00000433003.1.missense.224F/L MED14 F224L 3 LELLPDQA ENST00000433003.1 False False 1 HLA-B*45:01 4 None 5 0 838.855 1054.040 1.281 1.250 18.572 1.000 18.572 146.000 1.000 PoorBinder Pending chr2-53901384-53901385-G-C 126.PSME4.ENST00000404125.6.missense.1084H/D PSME4 H1084D 1 AEKIDRQYET ENST00000404125.6 True True 1 HLA-B*45:01 5 None 3 0 751.770 797.505 0.935 0.870 57.847 0.276 15.966 601.000 0.350 PoorBinder Pending @@ -33,7 +33,7 @@ chr1-179109009-179109010-T-C 71.ABL2.ENST00000502732.6.missense.753T/A 1 ABL2 chr9-137255473-137255474-G-C 557.NELFB.ENST00000343053.6.missense.37G/R NELFB G37R 1 GERAGDRAP ENST00000343053.6 True True 1 HLA-B*45:01 7 None 3 0 1287.920 1556.750 2.100 2.200 32.319 0.812 26.243 80.000 0.600 PoorBinder Pending chr15-49282070-49282071-G-T 806.GALK2.ENST00000327171.7.missense.186A/S GALK2 A186S 4 SEEGTAKLI ENST00000327171.7 False False 1 HLA-B*45:01 1 None 3 0 1350.480 625.225 1.850 1.000 24.473 1.000 24.473 184.000 1.000 PoorBinder Pending chr16-2295600-2295601-C-G 830.ABCA3.ENST00000301732.10.missense.801E/D ABCA3 E801D 2 LPRDSTHRF ENST00000301732.10 True True 1 HLA-B*82:02 4 None 3 0 572.913 614.950 0.325 0.372 6.120 0.628 3.843 86.000 0.578 PoorBinder Pending -chr22-37631020-37631021-C-G 1011.GGA1.ENST00000381756.9.missense.501P/A GGA1 P501A 3 EPARPPQQPV ENST00000381756.9 False False 1 HLA-B*82:02 3 None 2 0 1567.076 2850.731 0.340 0.660 51.482 0.435 22.395 386.000 0.436 PoorBinder Pending +chr22-37631020-37631021-C-G 1010.GGA1.ENST00000343632.9.missense.484P/A GGA1 P484A 3 EPARPPQQPV ENST00000343632.9 True True 1 HLA-B*82:02 3 None 2 0 1567.076 2850.731 0.340 0.660 51.482 0.435 22.395 386.000 0.436 PoorBinder Pending chr20-4182496-4182497-C-A 968.SMOX.ENST00000305958.9.missense.340Q/K SMOX Q340K 1 SLGVLKRKY ENST00000305958.9 True True 1 HLA-A*29:02 8 None 2 0 1564.540 1069.915 1.750 1.500 34.520 0.539 18.606 456.000 0.600 PoorBinder Pending chr2-216428741-216428742-C-G 193.SMARCAL1.ENST00000357276.9.missense.432L/V SMARCAL1 L432V 4 SEVDPKVVS ENST00000357276.9 True True 2 HLA-B*45:01 7 None 5 0 939.435 1105.330 1.550 1.950 14.405 0.520 7.491 179.000 0.457 PoorBinder Pending chr15-62819536-62819537-G-A 815.TLN2.ENST00000636159.2.missense.2265E/K TLN2 E2265K 3 TPKFKQQLAAF ENST00000636159.2 True True 5 HLA-B*82:02 3 None 5 0 920.870 1146.680 1.129 1.163 20.006 0.351 7.022 154.000 0.452 PoorBinder Pending @@ -51,7 +51,7 @@ chr2-175093191-175093192-C-G 161.ATF2.ENST00000264110.7.missense.352D/H ATF2 chr2-63942505-63942506-C-G 130.VPS54.ENST00000409558.8.missense.441D/H VPS54 D441H 3 WFDLLKHIF ENST00000409558.8 False False 1 HLA-A*29:02 7 None 3 0 1700.625 4880.860 1.698 3.496 12.384 1.000 12.384 86.000 1.000 PoorBinder Pending chr17-45119014-45119029-TAGACGGTCGTTGTTG-T 895.PLCD3.ENST00000619929.5.inframe_del.233-238SNNDRL/S 1 PLCD3 SNNDRL233-238S 1 SEGAEIEEFL ENST00000619929.5 True True 1 HLA-B*45:01 1 None 2 1 2864.235 9580.020 2.750 5.636 26.946 1.000 26.946 64.000 0.941 PoorBinder Pending chr6-70190343-70190344-G-C 358.COL19A1.ENST00000620364.5.missense.1019K/N COL19A1 K1019N 1 AVSFEEINKY ENST00000620364.5 True True 1 HLA-A*29:02 8 None 4 0 988.285 1523.585 1.380 2.100 10.708 0.269 2.880 52.000 0.255 PoorBinder Pending -chr8-38428419-38428420-G-A 467.FGFR1.ENST00000425967.8.missense.125S/L FGFR1 S125L 10 NVSDALPSL ENST00000425967.8 False False 1 HLA-B*82:02 9 None 2 0 4075.553 24456.640 3.600 18.000 143.964 0.999 143.820 1501.000 1.000 PoorBinder Pending +chr8-38428419-38428420-G-A 469.FGFR1.ENST00000447712.7.missense.125S/L FGFR1 S125L 10 NVSDALPSL ENST00000447712.7 True True 1 HLA-B*82:02 9 None 2 0 4075.553 24456.640 3.600 18.000 143.964 0.999 143.820 1501.000 1.000 PoorBinder Pending chr11-64320894-64320895-T-C 658.PRDX5.ENST00000265462.9.missense.157F/L PRDX5 F157L 3 LLADPTGAL ENST00000265462.9 True True 1 HLA-B*82:02 9 None 2 0 4209.230 5459.630 1.040 2.517 580.692 0.439 254.924 6089.000 0.427 PoorBinder Pending chr6-118491773-118491774-G-A 364.CEP85L.ENST00000360290.7.missense.348S/F CEP85L S348F 6 GEFEQKLAFT ENST00000360290.7 False False 1 HLA-B*45:01 9 None 7 0 1514.345 919.750 1.730 1.200 16.147 0.421 6.798 95.000 0.581 PoorBinder Pending chr19-6044262-6044263-G-C 916.RFX2.ENST00000303657.10.missense.37A/G RFX2 A37G 6 SPQRVLVQAG ENST00000303657.10 True True 1 HLA-B*82:02 10 None 2 0 2099.770 652.650 2.560 0.670 15.809 1.000 15.809 45.000 0.989 PoorBinder Pending @@ -59,7 +59,7 @@ chr1-39429921-39429922-G-C 26.MACF1.ENST00000564288.6.missense.5662E/Q MACF1 chr8-22566400-22566401-G-C 451.SORBS3.ENST00000240123.12.missense.336R/P SORBS3 R336P 1 APYLGSAPS ENST00000240123.12 True True 1 HLA-B*82:02 8 None 4 0 1824.250 4040.730 1.500 2.900 23.107 0.374 8.642 195.000 0.464 PoorBinder Pending chr6-3723707-3723708-C-G 327.PXDC1.ENST00000380283.5.missense.203E/Q PXDC1 E203Q 2 SEFPSQLEDG ENST00000380283.5 True True 1 HLA-B*45:01 6 None 2 0 1952.725 2692.965 2.800 3.050 22.483 0.539 12.118 406.000 0.418 PoorBinder Pending chr7-112342710-112342711-G-C 426.ZNF277.ENST00000361822.8.missense.445L/F ZNF277 L445F 2 SSIFNQLLL ENST00000361822.8 True True 1 HLA-A*29:02 4 None 2 0 3085.745 5117.275 3.033 5.250 58.592 0.347 20.331 505.000 0.434 PoorBinder Pending -chr12-49526214-49526215-G-A 685.SPATS2.ENST00000321898.10.missense.533R/H SPATS2 R533H 3 LPQHKPRTSQT ENST00000321898.10 False False 1 HLA-B*82:02 4 None 3 0 3325.660 3472.750 6.800 6.900 23.424 1.000 23.424 334.000 0.968 PoorBinder Pending +chr12-49526214-49526215-G-A 686.SPATS2.ENST00000552918.6.missense.533R/H SPATS2 R533H 3 LPQHKPRTSQT ENST00000552918.6 True True 2 HLA-B*82:02 4 None 3 0 3325.660 3472.750 6.800 6.900 23.424 1.000 23.424 334.000 0.968 PoorBinder Pending chr15-100900576-100900577-G-T 828.ALDH1A3.ENST00000329841.10.missense.296D/Y 2 ALDH1A3 D296Y 2 ADADLYLA ENST00000329841.10 True True 1 HLA-B*45:01 6 None 4 2 1933.954 5831.668 2.800 5.095 15.852 0.542 8.592 153.000 0.359 PoorBinder Pending chr18-14106118-14106119-G-C 902.ZNF519.ENST00000590202.3.missense.141P/A 1 ZNF519 P141A 1 AMNKYQHKF ENST00000590202.3 True True 1 HLA-A*29:02 1 None 3 1 1342.785 3172.260 1.650 4.277 8.050 0.350 2.817 20.000 0.453 PoorBinder Pending chr4-48420360-48420361-A-G 264.SLAIN2.ENST00000264313.11.missense.533R/G SLAIN2 R533G 3 RPAGTTAMG ENST00000264313.11 True True 1 HLA-B*82:02 9 None 2 0 3083.080 4526.880 3.500 3.300 58.280 0.312 18.183 365.000 0.290 PoorBinder Pending @@ -85,7 +85,7 @@ chr9-137199427-137199428-T-A 556.TPRN.ENST00000409012.6.missense.428E/D TPRN chr13-98431277-98431278-G-T 719.FARP1.ENST00000595437.5.missense.714R/L FARP1 R714L 5 LAALAEITEM ENST00000595437.5 False False 1 HLA-B*82:02 1 None 7 0 8075.950 8950.220 5.700 4.500 26.190 0.994 26.033 169.000 1.000 PoorBinder Pending chr11-6410863-6410864-C-T 639.APBB1.ENST00000609360.6.missense.162E/K APBB1 E162K 3 GEAEEEEKD ENST00000609360.6 True True 5 HLA-B*45:01 8 None 1 0 3743.880 2485.220 8.300 5.850 6.678 1.000 6.678 65.000 1.000 PoorBinder Pending chr17-7675087-7675088-C-T 862.TP53.ENST00000269305.9.missense.175R/H TP53 R175H 9 QHMTEVVRH ENST00000269305.9 True True 1 HLA-A*29:02 9 None 2 0 18290.766 27172.470 22.885 22.500 165.032 1.000 165.032 1415.000 0.989 PoorBinder Pending -chr20-17659330-17659331-C-T 975.RRBP1.ENST00000246043.8.missense.393E/K RRBP1 E393K 1 NQGKKVKGA ENST00000246043.8 False False 1 HLA-B*45:01 7 None 1 0 15310.574 12423.337 8.700 7.800 153.904 0.493 75.875 676.000 0.574 PoorBinder Pending +chr20-17659330-17659331-C-T 976.RRBP1.ENST00000377813.6.missense.393E/K RRBP1 E393K 1 NQGKKVKGA ENST00000377813.6 True True 1 HLA-B*45:01 7 None 1 0 15310.574 12423.337 8.700 7.800 153.904 0.493 75.875 676.000 0.574 PoorBinder Pending chr19-6755017-6755018-T-C 922.SH2D3A.ENST00000245908.11.missense.265E/G SH2D3A E265G 2 AEEDEGEENR ENST00000245908.11 True True 1 HLA-B*45:01 6 None 4 0 3176.655 3585.925 2.750 3.550 3.820 1.000 3.820 5.000 0.985 PoorBinder Pending chr16-87417563-87417564-G-C 851.ZCCHC14.ENST00000671377.2.missense.427L/V ZCCHC14 L427V 3 SPAILMPSSVQ ENST00000671377.2 True True NA HLA-B*82:02 10 None 3 0 3099.810 4196.680 3.700 3.390 12.705 0.248 3.151 153.000 0.277 PoorBinder Pending chr9-133354714-133354715-G-C 554.SURF1.ENST00000371974.8.missense.89N/K 1 SURF1 N89K 1 QVQRRKWKLKL ENST00000371974.8 True True 1 HLA-B*82:02 10 None 2 1 12382.340 10992.950 20.000 20.000 46.709 0.762 35.592 563.000 0.700 PoorBinder Pending @@ -98,7 +98,7 @@ chr2-61348284-61348285-C-G 127.USP34.ENST00000398571.7.missense.624D/H USP34 chr9-37784015-37784016-T-A 538.EXOSC3.ENST00000327304.10.missense.124K/N EXOSC3 K124N 1 VTANSGDIF ENST00000327304.10 True True 1 HLA-A*29:02 4 None 1 0 6920.210 9886.520 9.825 15.230 28.784 0.533 15.342 255.000 0.480 PoorBinder Pending chr19-14049194-14049196-CC-TT 932.IL27RA.ENST00000263379.4.missense.428A/V IL27RA A428V 1 VPPGTPAI ENST00000263379.4 True True 1 HLA-B*82:02 1 None 4 0 1844.100 1610.820 1.400 1.400 13.617 NA NA NA 0.268 PoorBinder Pending chr19-17052841-17052842-C-G 947.HAUS8.ENST00000593360.1.missense.243K/N HAUS8 K243N 2 SELKDVTAKN ENST00000593360.1 False False 1 HLA-B*45:01 10 None 1 0 4520.046 7503.075 5.050 3.950 10.348 0.602 6.229 98.000 0.548 PoorBinder Pending -chr15-40622778-40622779-C-T 782.KNL1.ENST00000346991.9.missense.865P/S KNL1 P865S 2 KPKFLKEKQNV ENST00000346991.9 False False 1 HLA-B*82:02 5 None 1 0 4676.230 4830.500 5.600 3.200 13.527 0.492 6.655 128.000 0.444 PoorBinder Pending +chr15-40622778-40622779-C-T 783.KNL1.ENST00000399668.7.missense.839P/S KNL1 P839S 2 KPKFLKEKQNV ENST00000399668.7 True True 1 HLA-B*82:02 5 None 1 0 4676.230 4830.500 5.600 3.200 13.527 0.492 6.655 128.000 0.444 PoorBinder Pending chr2-31366060-31366061-G-C 119.XDH.ENST00000379416.4.missense.791R/G XDH R791G 1 VPANRIVVGVK ENST00000379416.4 True True 1 HLA-B*82:02 9 None 1 0 5651.030 5324.550 3.800 7.344 9.677 1.000 9.677 83.000 1.000 PoorBinder Pending chr1-168179177-168179178-A-T 69.TIPRL.ENST00000367833.7.missense.34E/V TIPRL E34V 1 HIMKSADVV ENST00000367833.7 True True 1 HLA-C*06:02 9 None 1 0 11201.270 31909.930 12.594 49.812 55.746 0.332 18.508 927.000 0.273 PoorBinder Pending chr7-92077866-92077867-G-C 405.AKAP9.ENST00000356239.8.missense.2313D/H AKAP9 D2313H 1 KITTHNKVI ENST00000356239.8 True True 1 HLA-C*06:02 5 None 1 0 9351.740 21632.225 6.300 23.000 36.250 0.408 14.790 238.000 0.412 PoorBinder Pending @@ -115,7 +115,7 @@ chr7-82908982-82908983-C-G 396.PCLO.ENST00000333891.14.missense.4444W/S PCLO chr1-223264671-223264672-G-C 92.SUSD4.ENST00000366878.9.missense.228L/V SUSD4 L228V 5 VIWSSSPPR ENST00000366878.9 True True 1 HLA-A*29:02 1 None 2 0 9344.650 8282.775 5.539 6.352 24.362 0.203 4.945 236.000 0.374 PoorBinder Pending chr6-46662451-46662452-C-G 352.SLC25A27.ENST00000371347.10.missense.154Q/E SLC25A27 Q154E 1 LVKVEMQM ENST00000371347.10 True True 1 HLA-B*82:02 5 None 1 0 14407.490 11479.160 14.000 11.000 14.615 0.521 7.614 71.000 0.484 PoorBinder Pending chr14-32773880-32773881-G-T 737.AKAP6.ENST00000280979.9.missense.1192M/I AKAP6 M1192I 1 IGKESETL ENST00000280979.9 True True 1 HLA-C*06:02 1 None 1 0 11339.865 8491.965 11.295 9.744 2.905 1.000 2.905 6.000 0.607 PoorBinder Pending -chr15-40622778-40622780-CC-TT 784.KNL1.ENST00000346991.9.missense.865P/L KNL1 P865L 1 KPKFLKEK ENST00000346991.9 False False 1 HLA-B*82:02 5 None 1 0 10136.120 12328.520 15.166 12.930 13.527 NA NA NA 0.450 PoorBinder Pending +chr15-40622778-40622780-CC-TT 785.KNL1.ENST00000399668.7.missense.839P/L KNL1 P839L 1 KPKFLKEK ENST00000399668.7 True True 1 HLA-B*82:02 5 None 1 0 10136.120 12328.520 15.166 12.930 13.527 NA NA NA 0.450 PoorBinder Pending chr5-1814504-1814505-G-A 291.NDUFS6.ENST00000469176.1.missense.118R/H 1 NDUFS6 R118H 1 QPAHPHTPL ENST00000469176.1 False False 2 HLA-B*82:02 4 None 4 1 90.330 100.630 0.020 0.050 181.433 0.500 90.716 6.000 0.410 PoorTranscript Pending chr5-177460554-177460555-C-T 319.DBN1.ENST00000393565.6.missense.278E/K 6 DBN1 E278K 5 SESEVEKAA ENST00000393565.6 True True 5 HLA-B*45:01 7 None 14 6 58.840 48.155 0.200 0.145 109.087 0.009 0.982 1076.000 0.285 LowExpr Pending chr6-32181195-32181196-G-T 342.AGER.ENST00000375069.7.missense.404L/M 2 AGER L404M 3 AEMNQSEEPEA ENST00000375069.7 False False 1 HLA-B*45:01 3 None 8 2 128.870 342.105 0.165 0.335 2.211 0.462 1.021 26.000 0.510 LowExpr Pending @@ -126,7 +126,6 @@ chr7-155462475-155462476-A-G 450.EN2.ENST00000297375.4.missense.264Q/R 1 EN2 chr8-125436370-125436371-C-T 504.TRIB1.ENST00000311922.4.missense.340S/F 3 TRIB1 S340F 3 WFEFVLEPGY ENST00000311922.4 True True 1 HLA-A*29:02 4 None 6 3 107.970 111.211 0.500 0.432 78.491 0.102 8.006 795.000 0.133 Subclonal Pending chr14-55180753-55180754-G-A 743.DLGAP5.ENST00000247191.7.missense.202S/L 1 DLGAP5 S202L 3 MPTLLRMTRSA ENST00000247191.7 True True 1 HLA-B*82:02 4 None 6 1 466.680 434.980 0.730 0.670 53.642 0.224 12.016 825.000 0.240 Subclonal Pending chr8-125436370-125436372-CC-TT 507.TRIB1.ENST00000311922.4.missense.340S/F 1 TRIB1 S340F 3 FEFVLEPGY ENST00000311922.4 True True 1 HLA-A*29:02 3 None 4 1 461.290 1095.220 1.080 2.250 78.491 NA NA NA 0.136 Subclonal Pending -chr20-2312957-2312958-C-T 966.ENSG00000286022.ENST00000651531.1.missense.220R/C 1 ENSG00000286022 R220C 2 FRCDAATDV ENST00000651531.1 False True NA HLA-C*06:02 3 3 2 1 64.681 51.930 0.281 0.162 NA 0.000 NA 0.000 0.650 ProbPos Pending chr22-41524890-41524891-G-C 1014.ACO2.ENST00000216254.9.missense.510E/Q ACO2 E510Q 9 TLKFNPQTDY ENST00000216254.9 True True 1 HLA-A*29:02 7 None 6 0 710.204 789.700 1.778 1.939 119.616 0.238 28.469 1640.000 0.216 Poor Pending chr8-133256733-133256734-C-G 517.NDRG1.ENST00000674925.1.missense.44E/Q NDRG1 E44Q 1 QEQGQISGWT ENST00000674925.1 False False NA HLA-B*45:01 3 None 1 0 1438.699 2225.090 2.000 2.800 678.195 0.274 185.825 223.000 0.402 Poor Pending chr2-219471924-219471925-A-G 197.SPEG.ENST00000312358.12.missense.1258Y/C SPEG Y1258C 1 GPQHAGVCKSV ENST00000312358.12 True True 5 HLA-B*82:02 8 8 2 0 1430.070 1391.910 1.400 1.425 66.211 0.397 26.286 126.000 0.333 Poor Pending @@ -140,13 +139,13 @@ chr1-16972417-16972418-C-G 2.CROCC.ENST00000375541.10.missense.2009S/C CROCC chr7-82916602-82916603-C-A 398.PCLO.ENST00000333891.14.missense.3795D/Y PCLO D3795Y 3 EIYAKLRYL ENST00000333891.14 True True 2 HLA-C*06:02 3 None 10 0 700.485 2134.795 1.333 3.900 4.482 0.171 0.766 35.000 0.222 Poor Pending chr8-143805313-143805314-A-C 525.SCRIB.ENST00000320476.7.missense.823V/G SCRIB V823G 3 EPENAGTITPL ENST00000320476.7 False False 1 HLA-B*82:02 6 None 3 0 1186.806 2777.580 0.279 0.550 61.627 0.055 3.389 402.000 0.164 Poor Pending chr19-35841840-35841841-C-A 950.NPHS1.ENST00000378910.10.missense.897G/C NPHS1 G897C 2 TEHTYHQCG ENST00000378910.10 True True 1 HLA-B*45:01 8 8 2 0 685.930 1092.140 1.800 1.739 0.377 1.000 0.377 2.000 0.081 Poor Pending -chr7-102317255-102317256-A-G 425.SH2B2.ENST00000536178.3.missense.462H/R SH2B2 H462R 2 FRGTLSRV ENST00000536178.3 False False 1 HLA-C*06:02 2 None 3 0 943.695 7891.131 0.685 5.651 6.055 0.223 1.350 94.000 0.181 Poor Pending +chr7-102317255-102317256-A-G 424.SH2B2.ENST00000444095.3.missense.419H/R SH2B2 H419R 2 FRGTLSRV ENST00000444095.3 True True 2 HLA-C*06:02 2 None 3 0 943.695 7891.131 0.685 5.651 6.055 0.223 1.350 94.000 0.181 Poor Pending chr7-140024672-140024681-TCAAAGATCA-T 446.PARP12.ENST00000263549.8.inframe_del.662-665VIFE/E PARP12 VIFE662-665E 1 SIFEKHQVY ENST00000263549.8 True True 1 HLA-C*06:02 1 None 1 0 1443.035 1509.720 1.485 1.766 29.767 0.153 4.554 307.000 0.108 Poor Pending chr4-373601-373602-C-T 260.ZNF141.ENST00000240499.8.missense.389H/Y ZNF141 H389Y 1 NEHKKIYTG ENST00000240499.8 True True 1 HLA-B*45:01 7 None 3 0 1179.250 2770.935 2.150 3.200 2.222 0.821 1.824 39.000 0.917 Poor Pending chrX-9937278-9937279-G-C 1040.SHROOM2.ENST00000380913.8.missense.1245D/H SHROOM2 D1245H 3 LPHGLEKHQI ENST00000380913.8 True True 1 HLA-B*82:02 8 None 1 0 922.680 3078.659 1.300 2.103 0.608 1.000 0.608 4.000 1.000 Poor Pending chr4-103145955-103145956-C-G 267.CENPE.ENST00000265148.9.missense.1429R/T CENPE R1429T 1 IEMLGLSKTL ENST00000265148.9 True True 2 HLA-B*45:01 9 None 1 0 1905.710 3542.829 2.933 5.100 29.958 0.242 7.250 380.000 0.239 Poor Pending -chr8-66813873-66813874-C-T 481.SGK3.ENST00000345714.8.missense.92A/V SGK3 A92V 10 FIKQRRVGL ENST00000345714.8 False False 1 HLA-C*06:02 7 None 5 0 1208.969 2282.620 1.875 3.181 2.109 0.571 1.204 7.000 0.230 Poor Pending -chr15-45133932-45133933-G-A 802.DUOX1.ENST00000321429.8.missense.43R/K DUOX1 R43K 2 MEHKWGSKG ENST00000321429.8 False False 1 HLA-B*45:01 4 None 1 0 1211.600 1253.160 1.550 1.906 0.947 1.000 0.947 2.000 1.000 Poor Pending +chr8-66813873-66813874-C-T 487.SGK3.ENST00000521198.7.missense.92A/V SGK3 A92V 10 FIKQRRVGL ENST00000521198.7 True True 1 HLA-C*06:02 7 None 5 0 1208.969 2282.620 1.875 3.181 2.109 0.571 1.204 7.000 0.230 Poor Pending +chr15-45133932-45133933-G-A 803.DUOX1.ENST00000389037.7.missense.43R/K DUOX1 R43K 2 MEHKWGSKG ENST00000389037.7 True True 1 HLA-B*45:01 4 None 1 0 1211.600 1253.160 1.550 1.906 0.947 1.000 0.947 2.000 1.000 Poor Pending chr4-154491218-154491219-G-C 279.DCHS2.ENST00000357232.10.missense.46S/C DCHS2 S46C 2 QRCLLWLLV ENST00000357232.10 True True 1 HLA-C*06:02 3 3 3 0 1457.355 1233.455 2.575 1.663 2.425 1.000 2.425 17.000 0.963 Poor Pending chr5-141332647-141332648-C-T 310.PCDHGA1.ENST00000517417.3.missense.655S/F PCDHGA1 S655F 2 QPPLFATVTL ENST00000517417.3 True True 1 HLA-B*82:02 5 None 3 0 1145.590 1340.180 0.400 0.500 0.326 0.571 0.186 7.000 0.681 Poor Pending chr16-25246937-25246938-C-T 838.ZKSCAN2.ENST00000328086.12.missense.420E/K ZKSCAN2 E420K 1 FFKDMDALL ENST00000328086.12 True True 1 HLA-A*29:02 3 None 4 0 1700.785 1864.320 1.949 1.947 4.925 0.441 2.172 68.000 0.454 Poor Pending @@ -155,7 +154,7 @@ chr7-77600798-77600799-C-T 391.PTPN12.ENST00000248594.11.missense.230H/Y PTP chr16-74391670-74391671-C-T 847.NPIPB15.ENST00000692376.1.missense.308P/L NPIPB15 P308L 2 LPLSPLPPS ENST00000692376.1 True True NA HLA-B*82:02 3 None 4 0 1284.036 2751.980 2.200 2.500 10.432 0.015 0.156 68.000 0.409 Poor Pending chr3-52395054-52395055-C-T 216.DNAH1.ENST00000420323.7.missense.3655P/L DNAH1 P3655L 1 IELQTANLS ENST00000420323.7 True True 1 HLA-B*45:01 3 None 3 0 1832.460 8526.610 3.470 11.247 3.000 0.550 1.650 20.000 0.263 Poor Pending chrX-15355261-15355262-C-T 1044.VEGFD.ENST00000297904.4.missense.177E/K VEGFD E177K 1 VPKLVPVKV ENST00000297904.4 True True 1 HLA-B*82:02 3 None 2 0 1593.490 1485.270 0.470 1.448 0.674 1.000 0.674 5.000 0.987 Poor Pending -chr3-184239802-184239803-C-T 255.VWA5B2.ENST00000426955.6.missense.836A/V VWA5B2 A836V 3 APPAVPPQV ENST00000426955.6 False False 1 HLA-B*82:02 9 None 5 0 1362.180 2010.830 0.900 1.253 0.083 1.000 0.083 2.000 0.429 Poor Pending +chr3-184239802-184239803-C-T 256.VWA5B2.ENST00000691901.1.missense.836A/V VWA5B2 A836V 3 APPAVPPQV ENST00000691901.1 True True NA HLA-B*82:02 9 None 5 0 1362.180 2010.830 0.900 1.253 0.083 1.000 0.083 2.000 0.429 Poor Pending chr10-132163376-132163377-C-G 608.JAKMIP3.ENST00000684848.1.missense.797R/G 1 JAKMIP3 R797G 16 ILGERMELL ENST00000684848.1 True True NA HLA-C*06:02 3 None 5 1 2437.960 945.535 4.300 1.500 3.848 0.625 2.405 24.000 0.462 Poor Pending chr6-43587456-43587457-G-A 351.POLH.ENST00000372236.9.missense.153G/D POLH G153D 2 IEGLPQDPT ENST00000372236.9 True True 1 HLA-B*45:01 7 None 3 0 2977.985 3031.475 2.900 2.898 12.570 0.291 3.658 237.000 0.230 Poor Pending chr7-128815875-128815876-C-G 440.CCDC136.ENST00000297788.9.missense.1103S/C CCDC136 S1103C 2 SEEEEDDADC ENST00000297788.9 True True 1 HLA-B*45:01 10 10 4 0 2356.280 2591.061 4.350 5.425 4.998 0.250 1.250 32.000 0.200 Poor Pending @@ -164,7 +163,7 @@ chr8-125028638-125028639-T-C 493.WASHC5.ENST00000318410.12.missense.1135Y/C chr1-86453473-86453474-G-A 45.CLCA2.ENST00000370565.5.missense.754G/E CLCA2 G754E 1 LEVPAGPHP ENST00000370565.5 True True 1 HLA-B*45:01 2 None 1 0 2487.725 36247.860 5.200 52.612 0.509 1.000 0.509 2.000 0.575 Poor Pending chr9-129102403-129102404-T-C 547.CRAT.ENST00000318080.7.missense.209Y/C CRAT Y209C 6 HNCQFFELDVY ENST00000318080.7 True True 1 HLA-A*29:02 3 3 5 0 2350.677 907.740 2.296 1.800 11.624 0.018 0.209 169.000 0.275 Poor Pending chr1-150261628-150261629-G-A 50.CA14.ENST00000369111.9.missense.83G/S CA14 G83S 2 NSHTVQLSL ENST00000369111.9 True True 1 HLA-C*06:02 2 None 2 0 2040.835 4849.410 4.170 9.990 0.137 0.500 0.069 4.000 0.321 Poor Pending -chr14-91783159-91783160-T-A 755.TC2N.ENST00000340892.9.missense.471K/N TC2N K471N 5 AVNQWNETV ENST00000340892.9 False False 1 HLA-C*06:02 6 None 4 0 2392.720 2807.520 2.848 2.883 1.985 0.125 0.248 16.000 0.151 Poor Pending +chr14-91783159-91783160-T-A 757.TC2N.ENST00000435962.7.missense.471K/N TC2N K471N 5 AVNQWNETV ENST00000435962.7 True True 2 HLA-C*06:02 6 None 4 0 2392.720 2807.520 2.848 2.883 1.985 0.125 0.248 16.000 0.151 Poor Pending chr17-7588499-7588500-G-C 860.SOX15.ENST00000250055.3.missense.194Q/E SOX15 Q194E 2 LPESDPRL ENST00000250055.3 True True 1 HLA-B*82:02 3 None 2 0 2751.900 1269.610 1.796 1.400 0.580 0.692 0.401 13.000 0.722 Poor Pending chr20-10054508-10054509-G-C 974.ANKEF1.ENST00000378392.6.missense.694K/N ANKEF1 K694N 1 VPTTSEGNKV ENST00000378392.6 True True 1 HLA-B*82:02 8 None 2 0 3673.050 4129.120 2.500 3.100 3.908 0.382 1.493 34.000 0.521 Poor Pending chrX-43656385-43656386-C-A 1076.MAOA.ENST00000338702.4.missense.15D/E MAOA D15E 2 SIAGHMFEV ENST00000338702.4 True True 1 HLA-A*29:02 8 None 2 0 3238.095 4035.900 3.551 6.650 0.784 1.000 0.784 2.000 1.000 Poor Pending @@ -194,7 +193,7 @@ chr3-186164997-186164998-C-T 257.DGKG.ENST00000265022.8.missense.706E/K DGKG chr15-74280668-74280669-G-T 821.CCDC33.ENST00000398814.8.missense.297M/I CCDC33 M297I 1 LVLEYYSSTSI ENST00000398814.8 True True 2 HLA-B*82:02 11 None 1 0 8664.370 5900.970 14.000 5.900 0.158 1.000 0.158 1.000 0.585 Poor Pending chrX-68717715-68717716-G-A 1080.STARD8.ENST00000374599.8.missense.268G/S STARD8 G268S 1 AKNWAATSAS ENST00000374599.8 True True 1 HLA-B*45:01 10 None 1 0 13320.040 13900.995 17.000 15.500 0.753 1.000 0.753 3.000 1.000 Poor Pending chr1-227091906-227091907-GC-G 104.CDC42BPA.ENST00000366766.8.FS.778GC/G CDC42BPA FS778 1 EKVLLTEENKN ENST00000366766.8 True True 5 HLA-B*45:01 11 None 1 0 35971.633 34029.983 54.500 43.000 40.050 0.061 2.443 312.000 0.236 Poor Pending -chr1-183880710-183880711-A-C 73.RGL1.ENST00000304685.8.missense.209Y/S RGL1 Y209S 2 LLDSLTRMM ENST00000304685.8 False False 1 HLA-B*82:02 4 None 2 0 8711.370 9972.950 11.770 15.000 0.461 0.286 0.132 7.000 0.300 Poor Pending +chr1-183880710-183880711-A-C 74.RGL1.ENST00000360851.4.missense.174Y/S RGL1 Y174S 2 LLDSLTRMM ENST00000360851.4 True True 1 HLA-B*82:02 4 None 2 0 8711.370 9972.950 11.770 15.000 0.461 0.286 0.132 7.000 0.300 Poor Pending chr17-4818361-4818376-TGGACAGAATCCTGAA-T 856.PLD2.ENST00000263088.11.inframe_del.662-667VDRILK/V 1 PLD2 VDRILK662-667V 3 DEIVAHKQGW ENST00000263088.11 True True 1 HLA-B*45:01 1, 2, 3, 4 None 4 1 14493.215 44044.085 10.600 57.500 35.110 0.012 0.421 328.000 0.225 Poor Pending chr16-49281350-49281351-C-T 839.CBLN1.ENST00000219197.11.missense.39D/N CBLN1 D39N 1 NSNPTSDPT ENST00000219197.11 True True 1 HLA-B*82:02 1 None 1 0 26450.320 26985.390 43.000 55.000 0.713 0.400 0.285 5.000 0.215 Poor Pending chr22-37374977-37374978-G-A 1007.ELFN2.ENST00000402918.7.missense.186P/L ELFN2 P186L 1 ELAGNLFN ENST00000402918.7 True True 4 HLA-B*45:01 6 None 6 0 36629.230 39989.985 51.000 57.500 0.890 0.368 0.328 19.000 0.168 Poor Pending @@ -202,8 +201,9 @@ chr22-37570267-37570268-C-G 1008.LGALS2.ENST00000215886.6.missense.132E/Q LG chr11-20638483-20638484-T-A 640.SLC6A5.ENST00000525748.6.missense.632V/E 3 SLC6A5 V632E 1 YMFQLEDTY ENST00000525748.6 True True 1 HLA-A*29:02 6 None 10 3 11.735 9.050 0.107 0.065 0.006 0.000 0.000 1.000 0.452 NoExpr Pending chr20-59301546-59301547-G-T 993.EDN3.ENST00000395654.3.missense.64G/W 1 EDN3 G64W 7 GEWTVAPTA ENST00000395654.3 False False 1 HLA-B*45:01 3 None 9 1 42.900 80.960 0.050 0.095 0.019 0.000 0.000 0.000 0.220 NoExpr Pending chr18-60371739-60371740-T-G 907.MC4R.ENST00000299766.5.missense.204M/L 2 MC4R M204L 1 MFFTLLALM ENST00000299766.5 True True NA HLA-A*29:02 5 None 7 2 60.515 56.745 0.410 0.410 0.000 0.000 0.000 0.000 1.000 NoExpr Pending +chr20-2312957-2312958-C-T 965.TGM3.ENST00000381458.6.missense.201R/C 1 TGM3 R201C 2 FRCDAATDV ENST00000381458.6 True True 1 HLA-C*06:02 3 3 2 1 64.681 51.930 0.281 0.162 0.000 0.000 0.000 0.000 0.650 NoExpr Pending chr16-25221522-25221523-G-C 836.AQP8.ENST00000219660.6.missense.109M/I 1 AQP8 M109I 2 LNLVILLPY ENST00000219660.6 True True 1 HLA-A*29:02 5 None 3 1 67.053 74.412 0.400 0.485 0.000 0.000 0.000 0.000 0.247 NoExpr Pending -chr14-91235009-91235029-GGTACAGCTCATCGAGGAGTT-G 752.GPR68.ENST00000531499.2.FS.8-14GGTACAGCTCATCGAGGAGTT/G 4 2 GPR68 FS8-14 4 VRAAARQLV ENST00000531499.2 False False 1 HLA-C*06:02 NA None 15 6 73.376 NA 0.206 NA 0.177 0.000 0.000 34.000 0.093 NoExpr Pending +chr14-91235009-91235029-GGTACAGCTCATCGAGGAGTT-G 752.GPR68.ENST00000531499.2.FS.8-14GGTACAGCTCATCGAGGAGTT/G 2 1 GPR68 FS8-14 3 VRAAARQLV ENST00000531499.2 False False 1 HLA-C*06:02 NA None 15 3 73.376 NA 0.206 NA 0.177 0.000 0.000 34.000 0.093 NoExpr Pending chr15-69049033-69049034-G-C 820.NOX5.ENST00000530406.6.missense.631D/H 1 NOX5 D631H 5 LEMHQAEEA ENST00000530406.6 False False 1 HLA-B*45:01 4 None 4 1 116.010 142.260 0.300 0.300 0.160 0.000 0.000 0.000 0.396 NoExpr Pending chr10-60186848-60186849-G-T 578.ANK3.ENST00000373827.6.missense.645L/M 2 1 ANK3 L645M 3 MDIATTLMEY ENST00000373827.6 False False 1 HLA-A*29:02 8 None 4 3 132.065 99.645 0.710 0.500 0.163 0.000 0.000 0.000 0.134 NoExpr Pending chr2-195816717-195816718-T-G 187.DNAH7.ENST00000312428.11.missense.3224E/A 2 DNAH7 E3224A 1 LANIAPMYQY ENST00000312428.11 True True 1 HLA-A*29:02 5 None 3 2 182.919 327.976 0.895 1.095 0.478 0.000 0.000 0.000 0.167 NoExpr Pending @@ -211,7 +211,7 @@ chr17-11784434-11784435-G-C 883.DNAH9.ENST00000262442.9.missense.2653D/H 1 DN chr11-59364558-59364559-T-A 648.OR5AN1.ENST00000641998.1.missense.34V/E 3 1 OR5AN1 V34E 3 LEIYITSLA ENST00000641998.1 True True NA HLA-B*45:01 2 None 8 4 199.865 18565.460 0.470 19.595 0.154 0.000 0.000 0.000 0.116 NoExpr Pending chr22-46257698-46257699-G-A 1025.PKDREJ.ENST00000253255.7.missense.1875T/I 3 PKDREJ T1875I 1 LLHIYGSGGY ENST00000253255.7 True True NA HLA-A*29:02 4 None 10 3 237.219 234.675 0.950 0.900 0.020 0.000 0.000 1.000 0.270 NoExpr Pending chr4-114833618-114833619-A-G 273.NDST4.ENST00000264363.7.missense.795S/P 1 NDST4 S795P 1 YNYPEALTF ENST00000264363.7 True True 1 HLA-A*29:02 4 None 4 1 254.405 278.395 0.476 0.691 0.003 0.000 0.000 0.000 0.187 NoExpr Pending -chr14-70060889-70060890-C-G 749.SLC8A3.ENST00000381269.6.missense.612E/Q 1 SLC8A3 E612Q 3 YERQQNFFIA ENST00000381269.6 False False 1 HLA-B*45:01 5 None 6 1 257.402 172.575 0.505 0.375 0.023 0.000 0.000 0.000 1.000 NoExpr Pending +chr14-70060889-70060890-C-G 748.SLC8A3.ENST00000356921.7.missense.612E/Q 1 SLC8A3 E612Q 3 YERQQNFFIA ENST00000356921.7 True True 1 HLA-B*45:01 5 None 6 1 257.402 172.575 0.505 0.375 0.023 0.000 0.000 0.000 1.000 NoExpr Pending chr6-122781239-122781240-C-G 370.FABP7.ENST00000356535.4.missense.132P/A 1 FABP7 P132A 1 FSSAHTSHL ENST00000356535.4 False False 1 HLA-C*06:02 4 None 8 1 282.405 115.650 0.400 0.175 0.317 0.000 0.000 0.000 0.362 NoExpr Pending chr7-132508196-132508197-C-A 444.PLXNA4.ENST00000378539.5.missense.166S/I 1 PLXNA4 S166I 4 NEIGSVFGV ENST00000378539.5 False False 1 HLA-B*45:01 3 None 6 1 315.685 319.740 0.425 0.613 0.575 0.000 0.000 2.000 0.281 NoExpr Pending chr19-8969814-8969831-ACGTGGAATTTCCTTGTG-A 925.MUC16.ENST00000397910.8.FS.3175-3180ACGTGGAATTTCCTTGTG/A 1 1 MUC16 FS3175-3180 1 YRKGLPLPI ENST00000397910.8 False True 5 HLA-C*06:02 NA None 15 2 353.805 NA 0.729 NA 0.003 0.000 0.000 0.000 0.750 NoExpr Pending @@ -246,7 +246,7 @@ chr14-39247882-39247883-G-C 742.MIA2.ENST00000640607.2.missense.437D/H MIA2 chr11-56542446-56542447-T-C 644.OR5M11.ENST00000528616.5.missense.271K/E OR5M11 K271E 1 EESEIIAV ENST00000528616.5 True True NA HLA-B*45:01 4 None 6 0 1297.740 1343.450 0.690 0.980 0.000 0.000 0.000 0.000 0.291 NoExpr Pending chr19-38802098-38802099-G-A 951.LGALS4.ENST00000307751.9.missense.240R/C LGALS4 R240C 2 NPCMGNGTVV ENST00000307751.9 True True 1 HLA-B*82:02 3 3 2 0 1320.044 776.010 0.990 0.300 0.232 0.000 0.000 0.000 1.000 NoExpr Pending chrX-7843975-7843976-C-T 1039.VCX.ENST00000688183.1.missense.194P/L VCX P194L 4 VEEPLSQES ENST00000688183.1 True True NA HLA-B*45:01 5 None 5 0 1326.575 2515.045 2.000 3.650 0.000 0.000 0.000 0.000 1.000 NoExpr Pending -chr19-50625545-50625546-G-A 953.SYT3.ENST00000338916.8.missense.474S/F SYT3 S474F 3 FSDPYVKAF ENST00000338916.8 False False 1 HLA-C*06:02 9 None 5 0 1417.645 4654.358 1.400 8.231 0.000 0.000 0.000 0.000 0.540 NoExpr Pending +chr19-50625545-50625546-G-A 955.SYT3.ENST00000600079.6.missense.474S/F SYT3 S474F 3 FSDPYVKAF ENST00000600079.6 True True 1 HLA-C*06:02 9 None 5 0 1417.645 4654.358 1.400 8.231 0.000 0.000 0.000 0.000 0.540 NoExpr Pending chr2-201835739-201835740-A-C 192.CDK15.ENST00000652192.3.missense.276E/D CDK15 E276D 5 DALLGATDY ENST00000652192.3 True True NA HLA-A*29:02 8 None 3 0 1453.760 1102.930 2.478 1.900 0.204 0.000 0.000 0.000 0.574 NoExpr Pending chr11-123943666-123943667-G-C 669.OR6T1.ENST00000321252.3.missense.58Q/E OR6T1 Q58E 1 RLHIEMYFF ENST00000321252.3 True True NA HLA-A*29:02 5 None 8 0 1515.160 1031.360 1.900 1.310 0.000 0.000 0.000 0.000 0.448 NoExpr Pending chr11-193734-193735-G-A 609.SCGB1C1.ENST00000342878.3.missense.27D/N SCGB1C1 D27N 1 NEFFMDFLQTL ENST00000342878.3 True True 1 HLA-B*45:01 1 None 2 0 1532.815 3383.435 1.447 2.644 0.000 0.000 0.000 4.000 0.213 NoExpr Pending @@ -267,7 +267,7 @@ chr3-122927970-122927971-G-C 233.SEMA5B.ENST00000357599.8.missense.223I/M 2 S chr14-94463231-94463232-G-T 781.SERPINA9.ENST00000674397.2.missense.372T/N SERPINA9 T372N 7 ATAATTNKF ENST00000674397.2 True True NA HLA-A*29:02 7 None 2 0 2635.710 2182.040 2.800 2.150 0.035 0.000 0.000 0.000 0.461 NoExpr Pending chr10-115241629-115241630-G-A 580.ATRNL1.ENST00000355044.8.missense.531G/E ATRNL1 G531E 1 LINEAMLIF ENST00000355044.8 True True 1 HLA-A*29:02 4 None 2 0 2650.815 1918.075 2.200 2.075 0.262 0.000 0.000 0.000 0.443 NoExpr Pending chr4-176120051-176120052-G-A 287.WDR17.ENST00000508596.6.missense.165V/I WDR17 V165I 4 HTHQKGKIV ENST00000508596.6 True True 1 HLA-C*06:02 8 None 2 0 2657.255 2338.375 2.510 2.105 0.514 0.000 0.000 2.000 0.489 NoExpr Pending -chr13-37746421-37746422-C-T 713.TRPC4.ENST00000625583.2.missense.138E/K TRPC4 E138K 4 ILLDKQFSKF ENST00000625583.2 False False 1 HLA-A*29:02 9 None 1 0 3268.935 3184.415 2.750 2.050 0.053 0.000 0.000 0.000 0.507 NoExpr Pending +chr13-37746421-37746422-C-T 710.TRPC4.ENST00000379705.8.missense.138E/K TRPC4 E138K 4 ILLDKQFSKF ENST00000379705.8 True True 1 HLA-A*29:02 9 None 1 0 3268.935 3184.415 2.750 2.050 0.053 0.000 0.000 0.000 0.507 NoExpr Pending chr6-43283594-43283595-A-T 348.TTBK1.ENST00000259750.9.missense.952E/V TTBK1 E952V 1 VEFSAGGELG ENST00000259750.9 True True 1 HLA-B*45:01 1 None 3 0 3328.210 1943.335 3.950 2.100 0.015 0.000 0.000 0.000 0.267 NoExpr Pending chr6-29174125-29174126-C-T 336.OR2J2.ENST00000641417.1.missense.164T/I OR2J2 T164I 2 SALHSSFIF ENST00000641417.1 True True NA HLA-A*29:02 8 None 4 0 3407.595 2607.465 2.004 1.580 0.037 0.000 0.000 0.000 0.277 NoExpr Pending chr11-58190707-58190708-A-T 645.OR9Q2.ENST00000641291.1.missense.73Y/F OR9Q2 Y73F 1 FSSAIIPQM ENST00000641291.1 True True NA HLA-A*29:02 1 None 1 0 3429.470 2379.220 2.500 1.939 0.008 0.000 0.000 0.000 0.514 NoExpr Pending @@ -290,7 +290,7 @@ chr3-52517959-52517960-A-C 218.STAB1.ENST00000321725.10.missense.1573H/P STA chr9-81992222-81992223-C-G 542.SPATA31D1.ENST00000344803.3.missense.585Q/E SPATA31D1 Q585E 1 LAQPESPFRAL ENST00000344803.3 True True 2 HLA-B*82:02 5 None 1 0 4804.440 3725.780 1.800 1.517 0.000 1.000 0.000 2.000 0.693 NoExpr Pending chr11-1078020-1078022-CTA-C 623.MUC2.ENST00000675028.1.FS.178CTA/C MUC2 FS178 1 GLQSFRIPL ENST00000675028.1 False True NA HLA-B*82:02 5, 6, 7, 8 None 1 0 4962.950 17837.990 5.100 21.000 0.001 0.000 0.000 0.000 0.918 NoExpr Pending chr4-5988666-5988667-T-A 261.C4orf50.ENST00000531445.3.missense.1127M/L C4orf50 M1127L 1 REHLQGKAKL ENST00000531445.3 False True 5 HLA-B*45:01 10 None 1 0 5147.705 7818.115 3.000 3.200 0.025 0.000 0.000 0.000 0.946 NoExpr Pending -chr11-70087776-70087777-C-T 666.ANO1.ENST00000531349.6.missense.86P/L ANO1 P86L 4 LLNSLSVDL ENST00000531349.6 False False 1 HLA-C*06:02 9 None 5 0 5793.860 20782.765 9.350 50.859 0.764 0.000 0.000 0.000 0.187 NoExpr Pending +chr11-70087776-70087777-C-T 665.ANO1.ENST00000355303.10.missense.45P/L ANO1 P45L 4 LLNSLSVDL ENST00000355303.10 True True 1 HLA-C*06:02 9 None 5 0 5793.860 20782.765 9.350 50.859 0.764 0.000 0.000 0.000 0.187 NoExpr Pending chr17-10499040-10499041-G-A 882.MYH1.ENST00000226207.6.missense.1306S/L MYH1 S1306L 1 DEKDTLVSQLL ENST00000226207.6 True True 5 HLA-B*45:01 11 None 1 0 6105.965 9722.242 6.000 6.850 0.009 0.000 0.000 0.000 0.988 NoExpr Pending chr3-58210851-58210852-G-C 222.DNASE1L3.ENST00000394549.7.missense.19L/V DNASE1L3 L19V 1 LLSIHSAVAM ENST00000394549.7 True True 1 HLA-B*82:02 8 None 1 0 6262.790 6365.260 5.600 5.700 0.181 0.000 0.000 0.000 1.000 NoExpr Pending chr1-22660990-22660991-G-A 6.C1QB.ENST00000509305.6.missense.121A/T 1 C1QB A121T 2 ATQKITFSA ENST00000509305.6 True True 1 HLA-B*45:01 6 None 2 1 6294.760 5577.395 4.772 5.010 0.000 0.000 0.000 0.000 0.984 NoExpr Pending @@ -298,7 +298,7 @@ chr5-136274698-136274699-C-T 307.TRPC7.ENST00000513104.6.missense.368A/T 1 TR chr8-132948805-132948806-C-G 515.TG.ENST00000220616.9.missense.1755P/R 1 TG P1755R 2 LLSSRSVLL ENST00000220616.9 True True 1 HLA-A*29:02 5 None 2 1 7171.850 5825.865 9.075 7.300 0.721 0.000 0.000 0.000 0.992 NoExpr Pending chr2-94874875-94874876-T-A 142.TEKT4.ENST00000295201.5.missense.272C/S TEKT4 C272S 1 LRVLVDSI ENST00000295201.5 True True 1 HLA-C*06:02 7 None 1 0 8114.430 12821.558 7.343 9.050 0.614 0.000 0.000 0.000 0.446 NoExpr Pending chr14-24068642-24068643-G-A 727.CARMIL3.ENST00000342740.6.missense.1248E/K CARMIL3 E1248K 1 SPSPASQDGK ENST00000342740.6 True True 5 HLA-B*82:02 10 None 1 0 8129.136 10564.040 8.400 8.900 1.601 0.000 0.000 25.000 0.185 NoExpr Pending -chr14-94382907-94382908-C-G 760.SERPINA1.ENST00000355814.8.missense.110E/D SERPINA1 E110D 1 LEGLNFNLTD ENST00000355814.8 False False 1 HLA-B*45:01 10 None 1 0 8280.080 8248.135 10.800 10.250 4.892 0.000 0.000 0.000 0.180 NoExpr Pending +chr14-94382907-94382908-C-G 761.SERPINA1.ENST00000393087.9.missense.110E/D SERPINA1 E110D 1 LEGLNFNLTD ENST00000393087.9 True True 1 HLA-B*45:01 10 None 1 0 8280.080 8248.135 10.800 10.250 4.892 0.000 0.000 0.000 0.180 NoExpr Pending chr1-66834005-66834006-C-G 43.DNAI4.ENST00000371026.8.missense.626G/R DNAI4 G626R 2 SKWVIRKRL ENST00000371026.8 True True 1 HLA-C*06:02 8 None 4 0 8661.280 10706.560 3.755 16.000 7.011 0.000 0.000 0.000 0.605 NoExpr Pending chr21-30755335-30755336-C-T 998.KRTAP21-1.ENST00000335093.5.missense.15G/S KRTAP21-1 G15S 1 YGSSCGCGYG ENST00000335093.5 True True NA HLA-A*29:02 4 5,7 1 0 9080.475 10805.150 27.749 27.126 0.000 0.000 0.000 0.000 0.470 NoExpr Pending chr1-119895935-119895936-C-T 49.ADAM30.ENST00000369400.2.missense.134R/Q ADAM30 R134Q 1 LQGVFNIDA ENST00000369400.2 True True NA HLA-B*45:01 2 None 2 0 9528.310 14703.570 6.200 16.000 0.019 0.000 0.000 0.000 0.203 NoExpr Pending diff --git a/tests/test_data/top_score_filter/input.tsv b/tests/test_data/top_score_filter/input.tsv index 7e57f44e9..f91405c5a 100644 --- a/tests/test_data/top_score_filter/input.tsv +++ b/tests/test_data/top_score_filter/input.tsv @@ -1,1169 +1,843 @@ -Chromosome Start Stop Reference Variant Transcript Transcript Support Level Transcript Length Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Mutation Protein Position Gene Name HGVSc HGVSp HLA Allele Peptide Length Sub-peptide Position Mutation Position MT Epitope Seq WT Epitope Seq Best MT IC50 Score Method Best MT IC50 Score Corresponding WT IC50 Score Corresponding Fold Change Best MT Percentile Method Best MT Percentile Corresponding WT Percentile Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Median MT IC50 Score Median WT IC50 Score Median Fold Change Median MT Percentile Median WT Percentile NetMHC WT Score NetMHC MT Score NetMHC WT Percentile NetMHC MT Percentile PickPocket WT Score PickPocket MT Score PickPocket WT Percentile PickPocket MT Percentile Index cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count NNalign WT Score NNalign MT Score NNalign WT Percentile NNalign MT Percentile -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 2 9 ATLSRTLLL ATLSRTLLA PickPocket 2122.61 3272.12 1.542 NetMHC 0.12 5.1 76 0.158 NA NA NA NA NA NA 3816.925 14131.865 3.702 0.51 3.8 24991.61 5511.24 5.1 0.12 3272.12 2122.61 2.5 0.9 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.3142857142857143 1.3142857142857143 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 6 6 LLPLLPLLL LLPLLLLLL PickPocket 2551.25 3099.81 1.215 NetMHC 0.17 0.33 101 0.891 NA NA NA NA NA NA 4721.43 6167.26 1.306 0.785 1.265 9234.71 6891.61 0.33 0.17 3099.81 2551.25 2.2 1.4 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 5 7 PLLPLLPLL PLLPLLLLL NetMHC 8291.82 12130.52 1.463 NetMHC 0.27 0.61 101 0.891 NA NA NA NA NA NA 10139.345 14005.785 1.381 16.135 21.805 12130.52 8291.82 0.61 0.27 15881.05 11986.87 43.0 32.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 4 6 QRPGSAPTT QRPGSSPTT PickPocket 1362.11 1517.76 1.114 PickPocket 0.3 0.3 7 0.571 NA NA NA NA NA NA 6537.82 9406.765 1.439 0.435 1.05 17295.77 11713.53 1.8 0.57 1517.76 1362.11 0.3 0.3 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5714285714285714 -0.5714285714285714 True False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 9 1 ARPPQQPVP PRPPQQPVP PickPocket 1654.99 4242.33 2.563 PickPocket 0.4 4.8 245 0.486 NA NA NA NA NA NA 6693.895 10556.225 1.577 0.485 3.2 16870.12 11732.8 1.6 0.57 4242.33 1654.99 4.8 0.4 15.GGA1.ENST00000343632.4.missense.484P/A -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 8 1, 3, 4 PLLPLLLLL LLPLLLLLL NetMHC 12130.52 9234.71 0.761 NetMHC 0.61 0.33 101 0.891 NA NA NA NA NA NA 14005.785 6167.26 0.44 21.805 1.265 9234.71 12130.52 0.33 0.61 3099.81 15881.05 2.2 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 9 1 YLSDRCKIL CLSDRCKIL PickPocket 3491.59 5099.03 1.46 NetMHC 1.7 1.5 92 0.043 NA NA NA NA NA NA 10368.825 10737.38 1.036 2.35 4.25 16375.73 17246.06 1.5 1.7 5099.03 3491.59 7.0 3.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857163 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 6 4 PEPARPPQQ PEPPRPPQQ PickPocket 2873.7 2812.19 0.979 PickPocket 1.8 1.7 245 0.486 NA NA NA NA NA NA 10491.195 7573.6 0.722 1.9 1.17 12335.01 18108.69 0.64 2.0 2812.19 2873.7 1.7 1.8 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -1.7999999999999996 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 5 5 KFNPQTDYL KFNPETDYL PickPocket 12117.27 14722.66 1.215 NetMHC 2.1 2.4 136 0.25 NA NA NA NA NA NA 15232.4 16891.63 1.109 17.05 21.2 19060.6 18347.53 2.4 2.1 14722.66 12117.27 40.0 32.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.4714285714285715 -1.4714285714285715 False False False 0 False 1 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 1 9 VLCQRAKVE VLCQRAKVA PickPocket 7860.43 8758.62 1.114 NetMHC 2.5 2.8 113 0.044 NA NA NA NA NA NA 13711.555 14502.285 1.058 10.25 11.9 20245.95 19562.68 2.8 2.5 8758.62 7860.43 21.0 18.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.9857142857142857 0.0571428571428572 False False False 1 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 9 1 IYGSGGYAL TYGSGGYAL PickPocket 7945.94 9972.95 1.255 NetMHC 2.5 4.1 120 0.233 NA NA NA NA NA NA 13754.31 16702.035 1.214 10.25 14.55 23431.12 19562.68 4.1 2.5 9972.95 7945.94 25.0 18.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.32857142857142857 0.32857142857142857 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 3 7 VNEALNNLL VNEALNHLL PickPocket 13070.67 15208.39 1.164 NetMHC 3.0 1.8 30 0.1 NA NA NA NA NA NA 17059.365 16297.11 0.955 19.0 21.4 17385.83 21048.06 1.8 3.0 15208.39 13070.67 41.0 35.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.3857142857142856 0.3857142857142856 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 7 3 LVRSRTYDM LVHSRTYDM PickPocket 4625.9 6610.93 1.429 NetMHC 3.2 3.4 210 0.686 NA NA NA NA NA NA 12986.865 14203.32 1.094 4.45 8.2 21795.71 21347.83 3.4 3.2 6610.93 4625.9 13.0 5.7 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.9142857142857144 -0.5428571428571428 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 1 9 ALGWEFLAF ALGWEFLAS PickPocket 6682.85 8950.22 1.339 NetMHC 4.1 28.0 171 0.959 NA NA NA NA NA NA 14995.67 23104.49 1.541 8.55 24.5 37258.76 23308.49 28.0 4.1 8950.22 6682.85 21.0 13.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.9142857142857143 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 6 4 IGKHGGVSL IGKPGGVSL PickPocket 9447.76 7945.94 0.841 NetMHC 6.9 1.3 140 0.179 NA NA NA NA NA NA 18405.335 11610.23 0.631 14.95 9.65 15274.52 27362.91 1.3 6.9 7945.94 9447.76 18.0 23.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.10000000000000002 0.05714285714285713 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 7 3 GSAPTTVIY GSSPTTVIY PickPocket 8032.38 10414.04 1.297 NetMHC 6.9 12.0 7 0.571 NA NA NA NA NA NA 17734.85 20382.87 1.149 12.45 19.5 30351.7 27437.32 12.0 6.9 10414.04 8032.38 27.0 18.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.8857142857142858 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 4 6 VSPEPARPP VSPEPPRPP PickPocket 7692.16 8297.38 1.079 NetMHC 7.2 19.0 245 0.486 NA NA NA NA NA NA 17719.675 21359.715 1.205 12.1 19.0 34422.05 27747.19 19.0 7.2 8297.38 7692.16 19.0 17.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.7999999999999996 -0.8571428571428571 False False True 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 2 8 AVRPLELVY AVRPLELAY PickPocket 9245.51 10414.04 1.126 NetMHC 7.4 18.0 113 0.053 NA NA NA NA NA NA 18558.34 22246.465 1.199 14.7 22.5 34078.89 27871.17 18.0 7.4 10414.04 9245.51 27.0 22.0 6.USP18.ENST00000215794.7.missense.124A/V 0.1285714285714286 0.9142857142857144 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 1 9 VSLFGALVR VSLFGALVH PickPocket 6330.92 5681.68 0.897 NetMHC 8.2 7.3 210 0.686 NA NA NA NA NA NA 17492.43 16741.485 0.957 10.1 8.05 27801.29 28653.94 7.3 8.2 5681.68 6330.92 8.8 12.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R 1.6428571428571428 2.1714285714285713 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 7 5, 9 LPLLPLLLL LPLLLLLLG PickPocket 16946.23 38565.12 2.276 NetMHC 8.8 60.0 101 0.891 NA NA NA NA NA NA 23057.685 40666.925 1.764 27.4 70.5 42768.73 29169.14 60.0 8.8 38565.12 16946.23 81.0 46.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 8 2 NLFNCECDL NPFNCECDL PickPocket 23444.56 50000.0 2.133 NetMHC 9.0 20.0 303 0.135 NA NA NA NA NA NA 26403.425 42358.58 1.604 34.5 54.0 34717.16 29362.29 20.0 9.0 50000.0 23444.56 88.0 60.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 True 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 4 6 RPLELVYCL RPLELAYCL PickPocket 26985.39 25017.04 0.927 NetMHC 9.4 3.4 113 0.053 NA NA NA NA NA NA 28357.175 23403.545 0.825 37.7 33.2 21790.05 29728.96 3.4 9.4 25017.04 26985.39 63.0 66.0 6.USP18.ENST00000215794.7.missense.124A/V 1.9000000000000001 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 1 9 YQPCDDMDY YQPCDDMDC PickPocket 1864.16 1804.62 0.968 PickPocket 0.6 0.6 92 0.043 NA NA NA NA NA NA 15927.085 16858.635 1.058 5.2 7.3 31912.65 29990.01 14.0 9.8 1804.62 1864.16 0.6 0.6 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 3 8 TLSRTLLLA TLSRTLLAA PickPocket 7287.08 8664.37 1.189 NetMHC 12.0 25.0 76 0.158 NA NA NA NA NA NA 18767.43 22490.125 1.198 14.0 22.5 36315.88 30247.78 25.0 12.0 8664.37 7287.08 20.0 16.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0285714285714285 1.3142857142857143 False False False 0 False 0 NA NA NA NA -22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-E*01:01 9 9 9 NMSSFKLKQ NMSSFKLKE PickPocket 3890.57 3848.7 0.989 PickPocket 4.0 3.9 117 0.496 NA NA NA NA NA NA 17113.26 17432.18 1.019 8.0 8.45 31015.66 30335.95 13.0 12.0 3848.7 3890.57 3.9 4.0 14.LGALS2.ENST00000215886.4.missense.132E/Q -0.9000000000000001 -0.07142857142857155 False False False 0 True 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 9 1 EMSHFEPNE AMSHFEPNE PickPocket 3932.89 2443.19 0.621 PickPocket 4.2 1.3 113 0.044 NA NA NA NA NA NA 17166.29 15315.03 0.892 8.1 4.5 28186.87 30399.69 7.7 12.0 2443.19 3932.89 1.3 4.2 18.ACO2.ENST00000216254.4.missense.33A/E -1.9000000000000001 -1.1285714285714286 True False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 8 2 AFTRLTSEL ASTRLTSEL NetMHC 30541.45 30699.15 1.005 NetMHC 12.0 12.0 171 0.959 NA NA NA NA NA NA 33736.555 33033.27 0.979 45.5 45.0 30699.15 30541.45 12.0 12.0 35367.39 36931.66 78.0 79.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.3714285714285715 0.24285714285714272 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 6 4 FNPQTDYLT FNPETDYLT PickPocket 2551.25 2416.9 0.947 PickPocket 1.4 1.2 136 0.25 NA NA NA NA NA NA 16712.305 17461.505 1.045 6.7 8.1 32506.11 30873.36 15.0 12.0 2416.9 2551.25 1.2 1.4 19.ACO2.ENST00000216254.4.missense.510E/Q -1.0714285714285716 -1.0714285714285716 False False False 0 False 1 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 1 9 MVCELAGNL MVCELAGNP PickPocket 26985.39 42509.45 1.575 NetMHC 14.0 60.0 303 0.135 NA NA NA NA NA NA 29477.705 42658.77 1.447 40.0 72.0 42808.09 31970.02 60.0 14.0 42509.45 26985.39 84.0 66.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6428571428571427 1.4714285714285713 False False False 1 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 9 2, 3 LLPLLLLLG LPLLLLLLG PickPocket 4676.23 38565.12 8.247 PickPocket 5.9 81.0 101 0.891 NA NA NA NA NA NA 18328.65 40666.925 2.219 9.95 70.5 42768.73 31981.07 60.0 14.0 38565.12 4676.23 81.0 5.9 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.4285714285714293 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 3 7 QQRPGSAPT QQRPGSSPT PickPocket 15044.73 27575.71 1.833 NetMHC 15.0 18.0 7 0.571 NA NA NA NA NA NA 23844.505 30735.185 1.289 27.5 42.5 33894.66 32644.28 18.0 15.0 27575.71 15044.73 67.0 40.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.1142857142857143 -1.1142857142857143 True False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 5 5 SPEPARPPQ SPEPPRPPQ PickPocket 8758.62 10414.04 1.189 NetMHC 16.0 18.0 245 0.486 NA NA NA NA NA NA 20979.65 22234.49 1.06 18.5 22.5 34054.94 33200.68 18.0 16.0 10414.04 8758.62 27.0 21.0 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -1.6857142857142855 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 20 NA GCPWSGTGQ NA PickPocket 10527.33 NA NA NetMHC 17.0 NA 142 0.768 NA NA NA NA NA NA 21882.695 NA NA 22.0 NA NA 33238.06 NA 17.0 NA 10527.33 NA 27.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.1857142857142857 -0.32857142857142857 False False False 1 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 3 7 RTEASGYES RTEASGSES PickPocket 7366.35 21500.59 2.919 PickPocket 16.0 56.0 116 0.043 NA NA NA NA NA NA 20386.21 29661.16 1.455 16.5 43.0 37821.73 33406.07 30.0 17.0 21500.59 7366.35 56.0 16.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2142857142857142 -1.2 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 3 7 VRPLELVYC VRPLELAYC PickPocket 8387.64 12930.01 1.542 NetMHC 17.0 22.0 113 0.053 NA NA NA NA NA NA 21020.02 24267.335 1.154 18.0 28.5 35604.66 33652.4 22.0 17.0 12930.01 8387.64 35.0 19.0 6.USP18.ENST00000215794.7.missense.124A/V 1.1285714285714286 1.1285714285714286 False True False 1 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 8 2 SAPTTVIYE SSPTTVIYE PickPocket 4429.97 2077.17 0.469 PickPocket 5.2 0.8 7 0.571 NA NA NA NA NA NA 19201.975 18554.51 0.966 11.6 10.9 35031.85 33973.98 21.0 18.0 2077.17 4429.97 0.8 5.2 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.12857142857142861 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 2 8 QPCDDMDYL QPCDDMDCL NetMHC 34131.66 34638.75 1.015 NetMHC 18.0 20.0 92 0.043 NA NA NA NA NA NA 42065.83 42319.375 1.006 53.0 54.0 34638.75 34131.66 20.0 18.0 50000.0 50000.0 88.0 88.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.5142857142857142 -0.5142857142857142 True False False 1 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 2 8 VCELAGNLF VCELAGNPF PickPocket 17130.58 20149.14 1.176 NetMHC 19.0 32.0 303 0.135 NA NA NA NA NA NA 25730.19 29224.695 1.136 32.5 42.5 38300.25 34329.8 32.0 19.0 20149.14 17130.58 53.0 46.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 0.7000000000000001 False False False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 4 6 WEFLAFTRL WEFLASTRL NetMHC 35077.0 34584.44 0.986 NetMHC 21.0 20.0 171 0.959 NA NA NA NA NA NA 39258.18 37210.95 0.948 53.0 51.0 34584.44 35077.0 20.0 21.0 39837.46 43439.36 82.0 85.0 22.PANX2.ENST00000395842.2.missense.147S/F 1.4000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-E*01:01 9 2 9 SAAAAAAAV SAAAAAAAA PickPocket 21040.32 21040.32 1.0 NetMHC 21.0 30.0 128 0.977 NA NA NA NA NA NA 28125.2 29506.67 1.049 38.0 42.5 37973.02 35210.08 30.0 21.0 21040.32 21040.32 55.0 55.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.142857142857143 2.142857142857143 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 4 8 PPLLPLLPL PPLLPLLLL NetMHC 35483.9 31563.06 0.89 NetMHC 22.0 14.0 101 0.891 NA NA NA NA NA NA 42741.95 37737.485 0.883 55.0 49.5 31563.06 35483.9 14.0 22.0 43911.91 50000.0 85.0 88.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 4 6 ELAGNLFNC ELAGNPFNC PickPocket 12117.27 9972.95 0.823 NetMHC 23.0 17.0 303 0.135 NA NA NA NA NA NA 23882.17 21748.705 0.911 27.5 21.0 33524.46 35647.07 17.0 23.0 9972.95 12117.27 25.0 32.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.5 0.6857142857142856 True True False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 5 5 EFLAFTRLT EFLASTRLT NetMHC 35694.53 31850.89 0.892 NetMHC 23.0 14.0 171 0.959 NA NA NA NA NA NA 36114.375 25891.6 0.717 51.0 33.5 31850.89 35694.53 14.0 23.0 19932.31 36534.22 53.0 79.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.8999999999999997 1.4000000000000001 True False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 6 4 DMDYLSDRC DMDCLSDRC PickPocket 20813.9 18478.42 0.888 NetMHC 24.0 26.0 92 0.043 NA NA NA NA NA NA 28413.27 27614.355 0.972 39.5 37.5 36750.29 36012.64 26.0 24.0 18478.42 20813.9 49.0 55.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.042857142857143 -0.9857142857142857 False True False 1 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 3 9 PPPLLPLLP PPPLLPLLL PickPocket 29108.61 18478.42 0.635 NetMHC 24.0 2.7 101 0.891 NA NA NA NA NA NA 32658.89 19267.885 0.59 46.5 25.85 20057.35 36209.17 2.7 24.0 18478.42 29108.61 49.0 69.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.4857142857142858 1.4857142857142858 False False True 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 7 3 WTHSRDPEG WTRSRDPEG PickPocket 2523.8 1765.99 0.7 PickPocket 1.4 0.5 56 0.071 NA NA NA NA NA NA 19369.23 18322.905 0.946 12.7 10.25 34879.82 36214.66 20.0 24.0 1765.99 2523.8 0.5 1.4 5.CECR2.ENST00000262608.8.missense.535R/H -2.5 -2.1714285714285717 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 8 1 LLLAAAGGS TLLAAAGGS PickPocket 19088.05 20368.33 1.067 NetMHC 24.0 19.0 76 0.158 NA NA NA NA NA NA 27654.285 27433.97 0.992 37.5 36.0 34499.61 36220.52 19.0 24.0 20368.33 19088.05 53.0 51.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0857142857142856 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 9 1 TQKRNSRRQ AQKRNSRRQ PickPocket 17695.75 16763.86 0.947 NetMHC 25.0 28.0 96 0.042 NA NA NA NA NA NA 27006.015 27051.47 1.002 36.0 36.5 37339.08 36316.28 28.0 25.0 16763.86 17695.75 45.0 47.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6000000000000005 -3.0571428571428574 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 3 7 TVSPEPARP TVSPEPPRP PickPocket 33144.32 7692.16 0.232 NetMHC 26.0 5.6 245 0.486 NA NA NA NA NA NA 34982.33 16684.78 0.477 50.5 11.3 25677.4 36820.34 5.6 26.0 7692.16 33144.32 17.0 75.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.6857142857142855 -0.31428571428571433 False False True 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 6 NA RSAGSTGQG NA PickPocket 8664.37 NA NA PickPocket 20.0 NA 142 0.768 NA NA NA NA NA NA 23011.42 NA NA 24.0 NA NA 37358.47 NA 28.0 NA 8664.37 NA 20.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6285714285714287 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 3 7 CQRAKVEMS CQRAKVAMS PickPocket 4778.52 6062.77 1.269 PickPocket 6.2 9.9 113 0.044 NA NA NA NA NA NA 21085.485 22085.815 1.047 17.1 20.45 38108.86 37392.45 31.0 28.0 6062.77 4778.52 9.9 6.2 18.ACO2.ENST00000216254.4.missense.33A/E -0.6857142857142857 -0.6857142857142857 True False False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 6 4 FLAFTRLTS FLASTRLTS PickPocket 3343.7 3202.08 0.958 PickPocket 2.7 2.4 171 0.959 NA NA NA NA NA NA 20419.935 19400.67 0.95 15.85 12.2 35599.26 37496.17 22.0 29.0 3202.08 3343.7 2.4 2.7 22.PANX2.ENST00000395842.2.missense.147S/F 0.24285714285714272 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 8 2 PARPPQQPV PPRPPQQPV NetMHC 37726.09 38390.68 1.018 NetMHC 29.0 32.0 245 0.486 NA NA NA NA NA NA 43863.045 44195.34 1.008 58.5 60.0 38390.68 37726.09 32.0 29.0 50000.0 50000.0 88.0 88.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.7285714285714289 -1.7285714285714289 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 6 4 PGSAPTTVI PGSSPTTVI NetMHC 37748.53 39718.24 1.052 NetMHC 29.0 39.0 7 0.571 NA NA NA NA NA NA 43874.265 44859.12 1.022 58.5 63.5 39718.24 37748.53 39.0 29.0 50000.0 50000.0 88.0 88.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.9571428571428572 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 16 NA GEKAGCPWS NA PickPocket 8119.76 NA NA PickPocket 18.0 NA 142 0.768 NA NA NA NA NA NA 23066.335 NA NA 24.5 NA NA 38012.91 NA 31.0 NA 8119.76 NA 18.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 9 1 QDAAQGIAK EDAAQGIAK PickPocket 10191.11 12790.86 1.255 PickPocket 26.0 34.0 22 0.5 NA NA NA NA NA NA 24120.93 26133.085 1.083 28.5 35.5 39475.31 38050.75 37.0 31.0 12790.86 10191.11 34.0 26.0 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.3 0.35714285714285715 True False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 4 6 KEEEKTQEV KEEEKPQEV PickPocket 13070.67 13797.25 1.056 NetMHC 31.0 47.0 185 0.038 NA NA NA NA NA NA 25606.68 27404.275 1.07 33.0 42.0 41011.3 38142.69 47.0 31.0 13797.25 13070.67 37.0 35.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.0571428571428574 -2.0571428571428574 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 3 7 CELAGNLFN CELAGNPFN PickPocket 10527.33 7945.94 0.755 PickPocket 27.0 18.0 303 0.135 NA NA NA NA NA NA 24351.52 21388.74 0.878 29.0 19.0 34831.54 38175.71 20.0 31.0 7945.94 10527.33 18.0 27.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 0.6857142857142856 True False False 1 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 4 6 NEALNNLLT NEALNHLLT PickPocket 15044.73 15208.39 1.011 NetMHC 32.0 29.0 30 0.1 NA NA NA NA NA NA 26687.205 26477.45 0.992 36.0 35.0 37746.51 38329.68 29.0 32.0 15208.39 15044.73 41.0 40.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.7857142857142856 0.7857142857142856 False False False 0 True 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 7 3 KVEMSHFEP KVAMSHFEP PickPocket 9550.53 7527.49 0.788 PickPocket 24.0 16.0 113 0.044 NA NA NA NA NA NA 24092.905 21699.485 0.901 28.5 19.5 35871.48 38635.28 23.0 33.0 7527.49 9550.53 16.0 24.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 -0.3000000000000001 False False True 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 3 7 VTISCTGSS VTISCTRSS NetMHC 38650.33 36991.66 0.957 NetMHC 33.0 27.0 5 1.0 NA NA NA NA NA NA 40351.155 34366.06 0.852 58.5 50.0 36991.66 38650.33 27.0 33.0 31740.46 42051.98 73.0 84.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 2 8 SVNEALNNL SVNEALNHL PickPocket 20813.9 20813.9 1.0 NetMHC 33.0 32.0 30 0.1 NA NA NA NA NA NA 29741.95 29611.85 0.996 44.0 43.5 38409.8 38670.0 32.0 33.0 20813.9 20813.9 55.0 55.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 6 4 ALVRSRTYD ALVHSRTYD PickPocket 25564.3 23444.56 0.917 NetMHC 33.0 41.0 210 0.686 NA NA NA NA NA NA 32120.92 31774.645 0.989 48.5 50.5 40104.73 38677.54 41.0 33.0 23444.56 25564.3 60.0 64.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.5857142857142856 -0.09999999999999987 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 6 4 IANQDAAQG IANEDAAQG NetMHC 38788.59 39240.25 1.012 NetMHC 34.0 36.0 22 0.5 NA NA NA NA NA NA 42570.76 41576.08 0.977 60.0 60.5 39240.25 38788.59 36.0 34.0 43911.91 46352.93 85.0 86.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.5428571428571427 -0.08571428571428576 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 8 2 VRSRTYDMD VHSRTYDMD PickPocket 23192.26 21040.32 0.907 NetMHC 34.0 31.0 210 0.686 NA NA NA NA NA NA 31044.845 29587.16 0.953 47.0 43.0 38134.0 38897.43 31.0 34.0 21040.32 23192.26 55.0 60.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.7714285714285716 -1.5857142857142856 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 9 1 YESRVEPPH SESRVEPPH PickPocket 8387.64 10757.62 1.283 PickPocket 19.0 28.0 116 0.043 NA NA NA NA NA NA 23762.22 24573.94 1.034 27.5 30.0 38390.26 39136.8 32.0 36.0 10757.62 8387.64 28.0 19.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285714 -1.5714285714285712 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 8 2 NQDAAQGIA NEDAAQGIA PickPocket 18478.42 39837.46 2.156 NetMHC 36.0 46.0 22 0.5 NA NA NA NA NA NA 28851.06 40418.18 1.401 42.5 64.0 40998.9 39223.7 46.0 36.0 39837.46 18478.42 82.0 49.0 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.35714285714285715 0.35714285714285715 False False False 0 True 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 7 3 ELVYCLQKC ELAYCLQKC PickPocket 32434.8 25289.19 0.78 NetMHC 37.0 26.0 113 0.053 NA NA NA NA NA NA 35878.97 30993.52 0.864 55.5 45.0 36697.85 39323.14 26.0 37.0 25289.19 32434.8 64.0 74.0 6.USP18.ENST00000215794.7.missense.124A/V 0.6142857142857141 0.8571428571428571 True True False 2 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 8 2 VEMSHFEPN VAMSHFEPN PickPocket 27575.71 34610.27 1.255 NetMHC 37.0 38.0 113 0.044 NA NA NA NA NA NA 33527.865 37089.41 1.106 52.0 57.5 39568.55 39480.02 38.0 37.0 34610.27 27575.71 77.0 67.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 8 2 TTQKRNSRR TAQKRNSRR PickPocket 25017.04 42051.98 1.681 NetMHC 37.0 37.0 96 0.042 NA NA NA NA NA NA 32252.81 40701.4 1.262 50.0 60.5 39350.82 39488.58 37.0 37.0 42051.98 25017.04 84.0 63.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6 -2.5142857142857147 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 7 1, 2 TLLLAAAGG RTLLAAAGG PickPocket 22695.78 19505.61 0.859 NetMHC 38.0 46.0 76 0.158 NA NA NA NA NA NA 31150.365 30217.01 0.97 48.5 49.0 40928.41 39604.95 46.0 38.0 19505.61 22695.78 52.0 59.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.742857142857143 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 3 7 GWEFLAFTR GWEFLASTR PickPocket 10527.33 45854.11 4.356 PickPocket 27.0 86.0 171 0.959 NA NA NA NA NA NA 25118.7 44690.015 1.779 33.0 76.5 43525.92 39710.07 67.0 39.0 45854.11 10527.33 86.0 27.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.35714285714285704 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 19 NA AGCPWSGTG NA NetMHC 39974.77 NA NA NetMHC 40.0 NA 142 0.768 NA NA NA NA NA NA 41242.11 NA NA 62.0 NA NA 39974.77 NA 40.0 NA 42509.45 NA 84.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.3285714285714286 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 2 8 LCQRAKVEM LCQRAKVAM PickPocket 10874.65 11857.88 1.09 PickPocket 28.0 31.0 113 0.044 NA NA NA NA NA NA 25452.185 26071.115 1.024 34.0 36.5 40284.35 40029.72 42.0 40.0 11857.88 10874.65 31.0 28.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.0714285714285712 0.0571428571428572 False False False 1 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 1 9 YYSYGLLHI YYSYGLLHT PickPocket 4727.1 4830.5 1.022 PickPocket 6.0 6.3 120 0.233 NA NA NA NA NA NA 22387.515 23381.725 1.044 23.0 29.65 41932.95 40047.93 53.0 40.0 4830.5 4727.1 6.3 6.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9142857142857143 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 9 1 LFNCECDLF PFNCECDLF PickPocket 22695.78 50000.0 2.203 NetMHC 41.0 53.0 303 0.135 NA NA NA NA NA NA 31394.62 45933.37 1.463 50.0 70.5 41866.74 40093.46 53.0 41.0 50000.0 22695.78 88.0 59.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 7 3 ANQDAAQGI ANEDAAQGI PickPocket 8664.37 9972.95 1.151 PickPocket 20.0 25.0 22 0.5 NA NA NA NA NA NA 24392.79 25196.975 1.033 30.5 34.0 40421.0 40121.21 43.0 41.0 9972.95 8664.37 25.0 20.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 -0.4000000000000001 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 6 4 VWTHSRDPE VWTRSRDPE PickPocket 13947.35 15208.39 1.09 PickPocket 37.0 41.0 56 0.071 NA NA NA NA NA NA 27044.275 26957.82 0.997 39.0 37.5 38707.25 40141.2 34.0 41.0 15208.39 13947.35 41.0 37.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.5428571428571423 -1.3428571428571427 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 1 9 KSVNEALNN KSVNEALNH PickPocket 5382.48 5441.03 1.011 PickPocket 8.0 8.1 30 0.1 NA NA NA NA NA NA 22783.995 22279.39 0.978 24.5 21.55 39117.75 40185.51 35.0 41.0 5441.03 5382.48 8.1 8.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6 -0.21428571428571427 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 9 1 RSRTYDMDV HSRTYDMDV PickPocket 6903.33 8387.64 1.215 PickPocket 14.0 19.0 210 0.686 NA NA NA NA NA NA 23600.815 25560.14 1.083 28.0 39.5 42732.64 40298.3 60.0 42.0 8387.64 6903.33 19.0 14.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 5 5 GALVRSRTY GALVHSRTY PickPocket 29745.37 50000.0 1.681 NetMHC 42.0 65.0 210 0.686 NA NA NA NA NA NA 35029.685 46655.615 1.332 56.0 76.5 43311.23 40314.0 65.0 42.0 50000.0 29745.37 88.0 70.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.5428571428571428 -0.05714285714285732 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 5 5 VVVTTQKRN VVVTAQKRN PickPocket 22451.54 19932.31 0.888 NetMHC 42.0 44.0 96 0.042 NA NA NA NA NA NA 31421.625 30315.325 0.965 50.0 48.5 40698.34 40391.71 44.0 42.0 19932.31 22451.54 53.0 58.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -1.8 0.5428571428571433 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 7 3 CTGSSGSIA CTRSSGSIA PickPocket 34610.27 24218.04 0.7 NetMHC 43.0 33.0 5 1.0 NA NA NA NA NA NA 37519.795 31364.06 0.836 60.0 47.5 38510.08 40429.32 33.0 43.0 24218.04 34610.27 62.0 77.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.4428571428571428 0.4428571428571428 True False False 1 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 1 9 KAVRPLELV KAVRPLELA PickPocket 32787.64 32787.64 1.0 NetMHC 43.0 57.0 113 0.053 NA NA NA NA NA NA 36648.095 37620.74 1.027 58.5 65.5 42453.84 40508.55 57.0 43.0 32787.64 32787.64 74.0 74.0 6.USP18.ENST00000215794.7.missense.124A/V 0.9142857142857144 0.9142857142857144 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 4 6 TEASGYESR TEASGSESR PickPocket 25564.3 22942.68 0.897 NetMHC 44.0 43.0 116 0.043 NA NA NA NA NA NA 33069.985 31694.97 0.958 54.0 51.0 40447.26 40575.67 43.0 44.0 22942.68 25564.3 59.0 64.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.3571428571428572 -1.2 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 5 5 RPGSAPTTV RPGSSPTTV NetMHC 40594.12 38806.21 0.956 NetMHC 44.0 34.0 7 0.571 NA NA NA NA NA NA 44238.16 41122.785 0.93 65.5 59.5 38806.21 40594.12 34.0 44.0 43439.36 47882.2 85.0 87.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.2571428571428571 0.2571428571428571 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 2 8 HTVSPEPAR HTVSPEPPR PickPocket 5210.57 5154.5 0.989 PickPocket 7.4 7.2 245 0.486 NA NA NA NA NA NA 22958.865 22465.835 0.979 25.7 23.1 39777.17 40707.16 39.0 44.0 5154.5 5210.57 7.2 7.4 15.GGA1.ENST00000343632.4.missense.484P/A -0.8571428571428571 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 4 6 TVVVTTQKR TVVVTAQKR PickPocket 24747.82 24218.04 0.979 NetMHC 45.0 39.0 96 0.042 NA NA NA NA NA NA 32738.51 31990.935 0.977 54.0 50.5 39763.83 40729.2 39.0 45.0 24218.04 24747.82 62.0 63.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -0.7000000000000001 1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 2 8 GTLKFNPQT GTLKFNPET PickPocket 12930.01 13070.67 1.011 PickPocket 35.0 35.0 136 0.25 NA NA NA NA NA NA 26831.14 27035.22 1.008 40.0 40.5 40999.77 40732.27 46.0 45.0 13070.67 12930.01 35.0 35.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 -0.5000000000000001 False False False 0 False 1 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 3 7 TLKFNPQTD TLKFNPETD PickPocket 18082.85 17316.93 0.958 NetMHC 45.0 50.0 136 0.25 NA NA NA NA NA NA 29459.19 29409.41 0.998 46.5 48.5 41501.89 40835.53 50.0 45.0 17316.93 18082.85 47.0 48.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.9857142857142855 -0.942857142857143 False False False 0 False 1 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 7 3 NPQTDYLTG NPETDYLTG PickPocket 21970.92 25289.19 1.151 NetMHC 45.0 47.0 136 0.25 NA NA NA NA NA NA 31408.965 33193.335 1.057 51.0 55.5 41097.48 40847.01 47.0 45.0 25289.19 21970.92 64.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9000000000000001 -0.9000000000000001 False False False 0 True 1 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 3 7 VQGIANQDA VQGIANEDA PickPocket 15208.39 14564.23 0.958 PickPocket 41.0 39.0 22 0.5 NA NA NA NA NA NA 28075.265 28087.465 1.0 43.5 45.0 41610.7 40942.14 51.0 46.0 14564.23 15208.39 39.0 41.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 -0.0571428571428572 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 21 NA CPWSGTGQH NA NetMHC 40983.8 NA NA NetMHC 46.0 NA 142 0.768 NA NA NA NA NA NA 45491.9 NA NA 67.0 NA NA 40983.8 NA 46.0 NA 50000.0 NA 88.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.4142857142857141 -0.3285714285714286 True False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 4 6 CDDMDYLSD CDDMDCLSD PickPocket 9759.45 8950.22 0.917 PickPocket 24.0 21.0 92 0.043 NA NA NA NA NA NA 25379.61 25069.26 0.988 35.0 34.5 41188.3 40999.77 48.0 46.0 8950.22 9759.45 21.0 24.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142857 -0.5142857142857142 True False False 1 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 1 9 EERTEASGY EERTEASGS NetMHC 41033.07 42386.81 1.033 NetMHC 47.0 57.0 116 0.043 NA NA NA NA NA NA 45516.535 46193.405 1.015 67.5 72.5 42386.81 41033.07 57.0 47.0 50000.0 50000.0 88.0 88.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.342857142857143 -1.342857142857143 True False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 4 6 QRAKVEMSH QRAKVAMSH PickPocket 14564.23 12790.86 0.878 PickPocket 39.0 34.0 113 0.044 NA NA NA NA NA NA 27877.595 24624.24 0.883 43.5 29.5 36457.62 41190.96 25.0 48.0 12790.86 14564.23 34.0 39.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.5 -0.5 True False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 7 3 EPARPPQQP EPPRPPQQP NetMHC 41254.31 36882.54 0.894 NetMHC 48.0 26.0 245 0.486 NA NA NA NA NA NA 45627.155 33639.305 0.737 68.0 48.5 36882.54 41254.31 26.0 48.0 30396.07 50000.0 71.0 88.0 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -2.0714285714285716 True False True 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 6 4 ASGYESRVE ASGSESRVE PickPocket 24747.82 22209.93 0.897 NetMHC 48.0 47.0 116 0.043 NA NA NA NA NA NA 33019.82 31642.815 0.958 55.5 52.0 41075.7 41291.82 47.0 48.0 22209.93 24747.82 57.0 63.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.4000000000000001 -1.0142857142857145 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 8 2 THSRDPEGS TRSRDPEGS PickPocket 17130.58 18882.64 1.102 PickPocket 46.0 50.0 56 0.071 NA NA NA NA NA NA 29258.16 30370.17 1.038 47.5 51.5 41857.7 41385.74 53.0 49.0 18882.64 17130.58 50.0 46.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 7 3 VTTQKRNSR VTAQKRNSR PickPocket 18279.56 14722.66 0.805 NetMHC 49.0 37.0 96 0.042 NA NA NA NA NA NA 29838.925 27032.045 0.906 49.0 38.5 39341.43 41398.29 37.0 49.0 14722.66 18279.56 40.0 49.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.0571428571428574 -1.8 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 9 1 NLLTEEEDY HLLTEEEDY PickPocket 28795.36 18882.64 0.656 NetMHC 49.0 51.0 30 0.1 NA NA NA NA NA NA 35121.695 30253.42 0.861 59.0 50.5 41624.2 41448.03 51.0 49.0 18882.64 28795.36 50.0 69.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.742857142857143 -1.0142857142857145 False False False 0 True 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 5 5 LIGKHGGVS LIGKPGGVS PickPocket 25564.3 30396.07 1.189 NetMHC 50.0 54.0 140 0.179 NA NA NA NA NA NA 33518.955 36233.81 1.081 57.0 62.5 42071.55 41473.61 54.0 50.0 30396.07 25564.3 71.0 64.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.7000000000000001 0.05714285714285713 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 3 8, 9 GGGRSAGST GGGRSAGQH PickPocket 31740.46 29425.27 0.927 NetMHC 50.0 45.0 142 0.768 NA NA NA NA NA NA 36612.415 35130.625 0.96 61.5 57.5 40835.98 41484.37 45.0 50.0 29425.27 31740.46 70.0 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7285714285714286 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 5 5 RAKVEMSHF RAKVAMSHF NetMHC 41500.1 41442.2 0.999 NetMHC 50.0 49.0 113 0.044 NA NA NA NA NA NA 45750.05 41075.56 0.898 69.0 66.0 41442.2 41500.1 49.0 50.0 40708.92 50000.0 83.0 88.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.35714285714285715 -0.35714285714285715 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 17 NA EKAGCPWSG NA PickPocket 19088.05 NA NA NetMHC 50.0 NA 142 0.768 NA NA NA NA NA NA 30304.18 NA NA 50.5 NA NA 41520.31 NA 50.0 NA 19088.05 NA 51.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G 0.02857142857142855 0.02857142857142855 True False False 1 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 9 1 TQEVKVKEP PQEVKVKEP PickPocket 9346.08 22695.78 2.428 PickPocket 23.0 59.0 185 0.038 NA NA NA NA NA NA 25436.785 33041.96 1.299 36.5 62.5 43388.14 41527.49 66.0 50.0 22695.78 9346.08 59.0 23.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.1428571428571428 -1.0142857142857142 False False True 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 7 3 LAFTRLTSE LASTRLTSE NetMHC 41558.95 41511.32 0.999 NetMHC 50.0 50.0 171 0.959 NA NA NA NA NA NA 43215.725 36973.06 0.856 67.5 62.0 41511.32 41558.95 50.0 50.0 32434.8 44872.5 74.0 85.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.5142857142857143 0.8999999999999997 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 8 2 GYESRVEPP GSESRVEPP PickPocket 8208.09 8571.13 1.044 PickPocket 19.0 20.0 116 0.043 NA NA NA NA NA NA 24893.865 25226.19 1.013 34.5 36.5 41881.25 41579.64 53.0 50.0 8571.13 8208.09 20.0 19.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.6142857142857143 -1.4000000000000001 False False True 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 8 2 HIYGSGGYA HTYGSGGYA PickPocket 18478.42 25289.19 1.369 PickPocket 49.0 64.0 120 0.233 NA NA NA NA NA NA 30059.19 33821.28 1.125 50.0 60.5 42353.37 41639.96 57.0 51.0 25289.19 18478.42 64.0 49.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.39999999999999997 -0.014285714285714266 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 6 4 LELVYCLQK LELAYCLQK PickPocket 16946.23 13501.89 0.797 PickPocket 46.0 36.0 113 0.053 NA NA NA NA NA NA 29325.56 25763.355 0.879 48.5 33.5 38024.82 41704.89 31.0 51.0 13501.89 16946.23 36.0 46.0 6.USP18.ENST00000215794.7.missense.124A/V 0.7999999999999999 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 5 5 PLELVYCLQ PLELAYCLQ NetMHC 41747.79 40906.72 0.98 NetMHC 52.0 46.0 113 0.053 NA NA NA NA NA NA 45873.895 39945.685 0.871 70.0 63.5 40906.72 41747.79 46.0 52.0 38984.65 50000.0 81.0 88.0 6.USP18.ENST00000215794.7.missense.124A/V 0.8571428571428571 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 11 NA TGQGSGEKA NA PickPocket 11479.16 NA NA PickPocket 30.0 NA 142 0.768 NA NA NA NA NA NA 26614.605 NA NA 41.0 NA NA 41750.05 NA 52.0 NA 11479.16 NA 30.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.5285714285714287 -1.3857142857142857 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 4 6 DLIGKHGGV DLIGKPGGV PickPocket 36931.66 32787.64 0.888 NetMHC 52.0 54.0 140 0.179 NA NA NA NA NA NA 39372.5 37389.805 0.95 65.5 64.0 41991.97 41813.34 54.0 52.0 32787.64 36931.66 74.0 79.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.05714285714285713 0.05714285714285713 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 3 7 VKEEEKTQE VKEEEKPQE PickPocket 40270.83 6469.41 0.161 NetMHC 53.0 22.0 185 0.038 NA NA NA NA NA NA 41077.4 20994.9 0.511 67.5 17.5 35520.39 41883.97 22.0 53.0 6469.41 40270.83 13.0 82.0 12.NEFH.ENST00000310624.6.missense.830P/T -3.1571428571428575 -2.1142857142857143 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 9 1 VYCLQKCNV AYCLQKCNV PickPocket 25289.19 25289.19 1.0 NetMHC 53.0 71.0 113 0.053 NA NA NA NA NA NA 33596.78 34586.065 1.029 58.5 67.5 43882.94 41904.37 71.0 53.0 25289.19 25289.19 64.0 64.0 6.USP18.ENST00000215794.7.missense.124A/V 0.3 0.6142857142857141 False False False 2 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 2 8 SLFGALVRS SLFGALVHS PickPocket 13070.67 13648.77 1.044 PickPocket 35.0 37.0 210 0.686 NA NA NA NA NA NA 27492.97 28347.33 1.031 44.0 50.0 43045.89 41915.27 63.0 53.0 13648.77 13070.67 37.0 35.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R 0.9857142857142857 2.1714285714285713 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 6 4 SCTGSSGSI SCTRSSGSI PickPocket 18882.64 23192.26 1.228 PickPocket 50.0 60.0 5 1.0 NA NA NA NA NA NA 30413.015 31845.155 1.047 51.5 51.5 40498.05 41943.39 43.0 53.0 23192.26 18882.64 60.0 50.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.08571428571428566 0.08571428571428566 False False False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 9 1 QTDYLTGTD ETDYLTGTD NetMHC 41972.45 42738.65 1.018 NetMHC 54.0 60.0 136 0.25 NA NA NA NA NA NA 45986.225 46369.325 1.008 71.0 74.0 42738.65 41972.45 60.0 54.0 50000.0 50000.0 88.0 88.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9 -0.5 True False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 15 NA SGEKAGCPW NA PickPocket 19295.7 NA NA PickPocket 51.0 NA 142 0.768 NA NA NA NA NA NA 30648.155 NA NA 52.5 NA NA 42000.61 NA 54.0 NA 19295.7 NA 51.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8571428571428574 -0.6714285714285715 False False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 8 2 DYLSDRCKI DCLSDRCKI PickPocket 30396.07 40708.92 1.339 NetMHC 54.0 54.0 92 0.043 NA NA NA NA NA NA 36226.08 41400.25 1.143 62.5 68.5 42091.58 42056.09 54.0 54.0 40708.92 30396.07 83.0 71.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857146 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 2 8 AVQGIANQD AVQGIANED PickPocket 32434.8 32787.64 1.011 NetMHC 54.0 56.0 22 0.5 NA NA NA NA NA NA 37254.765 37526.545 1.007 64.0 65.0 42265.45 42074.73 56.0 54.0 32787.64 32434.8 74.0 74.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.157142857142857 0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 4 6 SHVWTHSRD SHVWTRSRD PickPocket 24218.04 25017.04 1.033 NetMHC 54.0 61.0 56 0.071 NA NA NA NA NA NA 33153.67 33931.095 1.023 58.0 62.0 42845.15 42089.3 61.0 54.0 25017.04 24218.04 63.0 62.0 5.CECR2.ENST00000262608.8.missense.535R/H -1.3428571428571427 -0.7714285714285714 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 4 6 TISCTGSSG TISCTRSSG PickPocket 31740.46 35367.39 1.114 NetMHC 54.0 69.0 5 1.0 NA NA NA NA NA NA 36915.345 39534.905 1.071 63.5 73.5 43702.42 42090.23 69.0 54.0 35367.39 31740.46 78.0 73.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.19999999999999998 0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 6 4 VVTTQKRNS VVTAQKRNS PickPocket 32085.75 28485.48 0.888 NetMHC 56.0 39.0 96 0.042 NA NA NA NA NA NA 37159.605 34157.16 0.919 65.0 54.0 39828.84 42233.46 39.0 56.0 28485.48 32085.75 69.0 74.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -2.5142857142857147 -0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 9 1 FTRLTSELN STRLTSELN PickPocket 11233.42 14252.45 1.269 PickPocket 29.0 38.0 171 0.959 NA NA NA NA NA NA 26733.44 28171.34 1.054 42.5 46.0 42090.23 42233.46 54.0 56.0 14252.45 11233.42 38.0 29.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.7714285714285715 -0.3714285714285715 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 5 5 EEEKTQEVK EEEKPQEVK NetMHC 42236.21 42913.81 1.016 NetMHC 56.0 61.0 185 0.038 NA NA NA NA NA NA 45582.925 46456.905 1.019 72.0 74.5 42913.81 42236.21 61.0 56.0 50000.0 48929.64 88.0 88.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -2.0571428571428574 True False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 8 2 KHGGVSLSK KPGGVSLSK PickPocket 6539.79 20149.14 3.081 PickPocket 13.0 53.0 140 0.179 NA NA NA NA NA NA 24389.595 31577.025 1.295 34.5 57.5 43004.91 42239.4 62.0 56.0 20149.14 6539.79 53.0 13.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.24285714285714294 0.3428571428571429 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 2 8 YQQRPGSAP YQQRPGSSP PickPocket 21269.21 20368.33 0.958 NetMHC 56.0 53.0 7 0.571 NA NA NA NA NA NA 31790.675 31138.39 0.979 56.0 53.0 41908.45 42312.14 53.0 56.0 20368.33 21269.21 53.0 56.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.5142857142857142 -1.5142857142857142 False False True 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 7 3 EKTQEVKVK EKPQEVKVK PickPocket 38150.11 15208.39 0.399 NetMHC 57.0 22.0 185 0.038 NA NA NA NA NA NA 40249.895 25270.105 0.628 68.5 31.5 35331.82 42349.68 22.0 57.0 15208.39 38150.11 41.0 80.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.0142857142857142 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 1 9 SGGSHVWTH SGGSHVWTR PickPocket 11112.54 12382.34 1.114 PickPocket 29.0 33.0 56 0.071 NA NA NA NA NA NA 26733.405 27527.46 1.03 43.0 46.0 42672.58 42354.27 59.0 57.0 12382.34 11112.54 33.0 29.0 5.CECR2.ENST00000262608.8.missense.535R/H -0.7142857142857143 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 5 5 EALNNLLTE EALNHLLTE PickPocket 32434.8 22942.68 0.707 NetMHC 57.0 54.0 30 0.1 NA NA NA NA NA NA 37433.52 32520.09 0.869 65.5 56.5 42097.5 42432.24 54.0 57.0 22942.68 32434.8 59.0 74.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.02857142857142847 0.7857142857142856 True False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 6 1, 2, 3 RTLLLAAAG SRTLLAAAG PickPocket 37333.42 30726.73 0.823 NetMHC 57.0 74.0 76 0.158 NA NA NA NA NA NA 39884.665 37467.34 0.939 68.5 73.0 44207.95 42435.91 74.0 57.0 30726.73 37333.42 72.0 80.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.342857142857143 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 3 7 TTVVVTTQK TTVVVTAQK NetMHC 42436.38 42705.84 1.006 NetMHC 57.0 59.0 96 0.042 NA NA NA NA NA NA 46218.19 39620.03 0.857 72.5 69.0 42705.84 42436.38 59.0 57.0 36534.22 50000.0 79.0 88.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 0.5428571428571433 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 6 4 EEKTQEVKV EEKPQEVKV PickPocket 33869.37 29425.27 0.869 NetMHC 58.0 25.0 185 0.038 NA NA NA NA NA NA 38170.325 32858.8 0.861 67.0 47.5 36292.33 42471.28 25.0 58.0 29425.27 33869.37 70.0 76.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.014285714285714 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 5 6, 7, 8, 9 GRSAGSTGQ GRSAGQHWA PickPocket 29108.61 23957.42 0.823 NetMHC 58.0 53.0 142 0.768 NA NA NA NA NA NA 35820.99 32946.32 0.92 63.5 57.0 41935.22 42533.37 53.0 58.0 23957.42 29108.61 61.0 69.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6857142857142857 -0.6857142857142857 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 7 NA SAGSTGQGS NA PickPocket 30726.73 NA NA NetMHC 58.0 NA 142 0.768 NA NA NA NA NA NA 36638.565 NA NA 65.0 NA NA 42550.4 NA 58.0 NA 30726.73 NA 72.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 8 2 TGSSGSIAS TRSSGSIAS PickPocket 10641.85 8571.13 0.805 PickPocket 27.0 20.0 5 1.0 NA NA NA NA NA NA 26618.01 25216.455 0.947 42.5 36.5 41861.78 42594.17 53.0 58.0 8571.13 10641.85 20.0 27.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.38571428571428573 0.4428571428571428 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 14 NA GSGEKAGCP NA PickPocket 20368.33 NA NA PickPocket 53.0 NA 142 0.768 NA NA NA NA NA NA 31490.0 NA NA 56.0 NA NA 42611.67 NA 59.0 NA 20368.33 NA 53.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.6714285714285715 False False True 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 6 4 AKVEMSHFE AKVAMSHFE PickPocket 27875.69 23699.6 0.85 NetMHC 59.0 40.0 113 0.044 NA NA NA NA NA NA 35246.91 31876.36 0.904 63.5 50.5 40053.12 42618.13 40.0 59.0 23699.6 27875.69 61.0 68.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.3000000000000001 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 1 9 WYQQRPGSA WYQQRPGSS PickPocket 9972.95 9865.62 0.989 PickPocket 25.0 25.0 7 0.571 NA NA NA NA NA NA 26322.295 26319.26 1.0 42.0 42.5 42772.9 42671.64 60.0 59.0 9865.62 9972.95 25.0 25.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.7857142857142858 -1.7857142857142858 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 6 4 LLHIYGSGG LLHTYGSGG NetMHC 42704.9 42372.14 0.992 NetMHC 59.0 57.0 120 0.233 NA NA NA NA NA NA 46352.45 46186.07 0.996 73.5 72.5 42372.14 42704.9 57.0 59.0 50000.0 50000.0 88.0 88.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.2857142857142857 0.914285714285714 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 7 3 LHIYGSGGY LHTYGSGGY PickPocket 30396.07 23444.56 0.771 NetMHC 60.0 58.0 120 0.233 NA NA NA NA NA NA 36598.6 32997.25 0.902 65.5 59.0 42549.94 42801.13 58.0 60.0 23444.56 30396.07 60.0 71.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.014285714285714266 0.3142857142857142 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 3 7 GSHVWTHSR GSHVWTRSR PickPocket 42051.98 38565.12 0.917 NetMHC 61.0 65.0 56 0.071 NA NA NA NA NA NA 42461.775 40932.55 0.964 72.5 73.0 43299.98 42871.57 65.0 61.0 38565.12 42051.98 81.0 84.0 5.CECR2.ENST00000262608.8.missense.535R/H -1.3000000000000003 -0.7142857142857143 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 7 3 MDYLSDRCK MDCLSDRCK PickPocket 22209.93 18882.64 0.85 PickPocket 57.0 50.0 92 0.043 NA NA NA NA NA NA 32641.64 30971.94 0.949 60.0 56.5 43061.24 43073.35 63.0 63.0 18882.64 22209.93 50.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.0999999999999999 -1.042857142857143 False False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 2 8 TVTISCTGS TVTISCTRS PickPocket 39408.75 36534.22 0.927 NetMHC 63.0 52.0 5 1.0 NA NA NA NA NA NA 41249.68 39168.35 0.95 72.5 65.5 41802.48 43090.61 52.0 63.0 36534.22 39408.75 79.0 82.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5142857142857142 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 2 8 YSYGLLHIY YSYGLLHTY PickPocket 28795.36 31740.46 1.102 NetMHC 63.0 74.0 120 0.233 NA NA NA NA NA NA 35945.78 37961.78 1.056 66.0 73.5 44183.1 43096.2 74.0 63.0 31740.46 28795.36 73.0 69.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.8428571428571427 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 1 9 LHTVSPEPA LHTVSPEPP PickPocket 11730.27 11986.87 1.022 PickPocket 31.0 32.0 245 0.486 NA NA NA NA NA NA 27443.1 27493.335 1.002 47.5 47.0 42999.8 43155.93 62.0 64.0 11986.87 11730.27 32.0 31.0 15.GGA1.ENST00000343632.4.missense.484P/A -0.31428571428571433 -0.2571428571428572 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 1 9 AKTTVVVTT AKTTVVVTA PickPocket 17505.31 18478.42 1.056 PickPocket 47.0 49.0 96 0.042 NA NA NA NA NA NA 30357.955 31093.01 1.024 55.5 59.0 43707.6 43210.6 69.0 64.0 18478.42 17505.31 49.0 47.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.4000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 4 7, 8, 9 GGRSAGSTG GGRSAGQHW PickPocket 32434.8 15541.08 0.479 NetMHC 64.0 51.0 142 0.768 NA NA NA NA NA NA 37834.855 28600.435 0.756 69.0 46.5 41659.79 43234.91 51.0 64.0 15541.08 32434.8 42.0 74.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7857142857142857 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 3 7 LFGALVRSR LFGALVHSR PickPocket 31740.46 34610.27 1.09 NetMHC 65.0 61.0 210 0.686 NA NA NA NA NA NA 37502.425 38721.69 1.033 69.0 69.0 42833.11 43264.39 61.0 65.0 34610.27 31740.46 77.0 73.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.05714285714285732 1.6428571428571428 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 5 5 ISCTGSSGS ISCTRSSGS PickPocket 37739.56 17130.58 0.454 NetMHC 65.0 41.0 5 1.0 NA NA NA NA NA NA 40510.88 28614.4 0.706 72.5 43.5 40098.22 43282.2 41.0 65.0 17130.58 37739.56 46.0 80.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.20000000000000004 0.5 False False False 1 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 5 5 HVWTHSRDP HVWTRSRDP PickPocket 28485.48 16404.99 0.576 NetMHC 67.0 45.0 56 0.071 NA NA NA NA NA NA 36004.06 28568.85 0.793 68.0 44.5 40732.71 43522.64 45.0 67.0 16404.99 28485.48 44.0 69.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1714285714285717 -1.3000000000000003 False False True 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 4 7 LSRTLLLAA LSRTLLAAA PickPocket 9245.51 30068.96 3.252 PickPocket 22.0 71.0 76 0.158 NA NA NA NA NA NA 26418.47 37679.99 1.426 45.0 78.5 45291.02 43591.43 86.0 68.0 30068.96 9245.51 71.0 22.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.4 1.4 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 4 6 QGIANQDAA QGIANEDAA NetMHC 43674.52 43845.46 1.004 NetMHC 69.0 70.0 22 0.5 NA NA NA NA NA NA 46837.26 46387.55 0.99 78.5 79.0 43845.46 43674.52 70.0 69.0 48929.64 50000.0 88.0 88.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.08571428571428576 -0.08571428571428576 True False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 1 9 AGTLKFNPQ AGTLKFNPE PickPocket 18082.85 17888.25 0.989 PickPocket 48.0 48.0 136 0.25 NA NA NA NA NA NA 30892.395 30886.785 1.0 58.5 59.5 43885.32 43701.94 71.0 69.0 17888.25 18082.85 48.0 48.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 -0.0142857142857143 False False False 0 False 1 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 6 4 ALNNLLTEE ALNHLLTEE NetMHC 43704.3 43374.07 0.992 NetMHC 69.0 66.0 30 0.1 NA NA NA NA NA NA 46852.15 46687.035 0.996 78.5 77.0 43374.07 43704.3 66.0 69.0 50000.0 50000.0 88.0 88.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.7857142857142856 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 5 5 EASGYESRV EASGSESRV NetMHC 43708.56 42167.71 0.965 NetMHC 69.0 55.0 116 0.043 NA NA NA NA NA NA 46854.28 46083.855 0.984 78.5 71.5 42167.71 43708.56 55.0 69.0 50000.0 50000.0 88.0 88.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.0142857142857145 -1.0142857142857145 True False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 4 6 LKFNPQTDY LKFNPETDY NetMHC 43715.19 43923.32 1.005 NetMHC 69.0 71.0 136 0.25 NA NA NA NA NA NA 46059.14 45138.125 0.98 78.0 78.5 43923.32 43715.19 71.0 69.0 46352.93 48403.09 86.0 87.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.6142857142857143 -0.942857142857143 False False False 0 False 1 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 9 1 APTTVIYED SPTTVIYED NetMHC 43734.11 44150.6 1.01 NetMHC 69.0 74.0 7 0.571 NA NA NA NA NA NA 45295.645 42651.185 0.942 78.0 78.5 44150.6 43734.11 74.0 69.0 41151.77 46857.18 83.0 87.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.14285714285714274 0.8857142857142858 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 3 7 PCDDMDYLS PCDDMDCLS NetMHC 43774.34 43881.05 1.002 NetMHC 70.0 71.0 92 0.043 NA NA NA NA NA NA 45828.27 46940.525 1.024 78.5 79.5 43881.05 43774.34 71.0 70.0 50000.0 47882.2 88.0 87.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142858 -0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 2 9 GGGGRSAGS GGGGRSAGQ PickPocket 14407.49 13212.86 0.917 PickPocket 39.0 35.0 142 0.768 NA NA NA NA NA NA 29091.395 28215.94 0.97 54.5 49.5 43219.02 43775.3 64.0 70.0 13212.86 14407.49 35.0 39.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.7285714285714285 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 7 3 SGYESRVEP SGSESRVEP PickPocket 16946.23 12653.21 0.747 PickPocket 46.0 34.0 116 0.043 NA NA NA NA NA NA 30373.56 28090.505 0.925 58.0 50.5 43527.8 43800.89 67.0 70.0 12653.21 16946.23 34.0 46.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285712 -1.0142857142857145 False False True 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 5 5 GLLHIYGSG GLLHTYGSG NetMHC 43848.77 43122.33 0.983 NetMHC 70.0 63.0 120 0.233 NA NA NA NA NA NA 46924.385 40227.875 0.857 79.0 71.5 43122.33 43848.77 63.0 70.0 37333.42 50000.0 80.0 88.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.3142857142857142 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 2 8 ERTEASGYE ERTEASGSE PickPocket 29425.27 32085.75 1.09 PickPocket 70.0 74.0 116 0.043 NA NA NA NA NA NA 36668.12 38304.3 1.045 70.5 76.0 44522.85 43910.97 78.0 71.0 32085.75 29425.27 74.0 70.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2 -1.2 True False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 5 5 GIANQDAAQ GIANEDAAQ PickPocket 18279.56 22209.93 1.215 PickPocket 49.0 57.0 22 0.5 NA NA NA NA NA NA 31145.685 33192.68 1.066 60.5 65.5 44175.43 44011.81 74.0 72.0 22209.93 18279.56 57.0 49.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.2285714285714284 -0.08571428571428576 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 7 3 LNNLLTEEE LNHLLTEEE PickPocket 27278.95 23957.42 0.878 PickPocket 67.0 61.0 30 0.1 NA NA NA NA NA NA 35686.605 33783.395 0.947 70.0 64.5 43609.37 44094.26 68.0 73.0 23957.42 27278.95 61.0 67.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.02857142857142847 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 1 9 KTVTISCTG KTVTISCTR PickPocket 27575.71 29108.61 1.056 PickPocket 67.0 69.0 5 1.0 NA NA NA NA NA NA 35874.375 36429.17 1.015 70.5 69.0 43749.73 44173.04 69.0 74.0 29108.61 27575.71 69.0 67.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 1.2285714285714284 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 7 3 GKHGGVSLS GKPGGVSLS NetMHC 44176.89 39664.56 0.898 NetMHC 74.0 38.0 140 0.179 NA NA NA NA NA NA 45015.5 27602.82 0.613 80.0 40.0 39664.56 44176.89 38.0 74.0 15541.08 45854.11 42.0 86.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.3428571428571429 0.3428571428571429 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 18 NA KAGCPWSGT NA NetMHC 44205.56 NA NA NetMHC 74.0 NA 142 0.768 NA NA NA NA NA NA 47102.78 NA NA 81.0 NA NA 44205.56 NA 74.0 NA 50000.0 NA 88.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.32857142857142857 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 9 1 GSSGSIASN RSSGSIASN PickPocket 16763.86 9972.95 0.595 PickPocket 45.0 25.0 5 1.0 NA NA NA NA NA NA 30509.11 25781.925 0.845 60.0 38.0 41590.9 44254.36 51.0 75.0 9972.95 16763.86 25.0 45.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.0 0.4428571428571428 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 13 NA QGSGEKAGC NA PickPocket 38150.11 NA NA NetMHC 75.0 NA 142 0.768 NA NA NA NA NA NA 41207.745 NA NA 77.5 NA NA 44265.38 NA 75.0 NA 38150.11 NA 80.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6714285714285715 -0.6714285714285715 True True False 1 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 4 6 FGALVRSRT FGALVHSRT PickPocket 42051.98 40708.92 0.968 NetMHC 75.0 69.0 210 0.686 NA NA NA NA NA NA 43162.765 42219.865 0.978 79.5 76.0 43730.81 44273.55 69.0 75.0 40708.92 42051.98 83.0 84.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.09999999999999987 0.9857142857142857 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 12 NA GQGSGEKAG NA PickPocket 18882.64 NA NA PickPocket 50.0 NA 142 0.768 NA NA NA NA NA NA 31582.635 NA NA 62.5 NA NA 44282.63 NA 75.0 NA 18882.64 NA 50.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0857142857142859 -1.0857142857142859 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 2 8 KTTVVVTTQ KTTVVVTAQ PickPocket 38984.65 41151.77 1.056 NetMHC 75.0 82.0 96 0.042 NA NA NA NA NA NA 41638.91 43031.81 1.033 78.0 82.5 44911.85 44293.17 82.0 75.0 41151.77 38984.65 83.0 81.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.0000000000000002 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 8 2 LVYCLQKCN LAYCLQKCN NetMHC 44314.74 44222.78 0.998 NetMHC 75.0 74.0 113 0.053 NA NA NA NA NA NA 45333.835 47111.39 1.039 80.5 81.0 44222.78 44314.74 74.0 75.0 50000.0 46352.93 88.0 86.0 6.USP18.ENST00000215794.7.missense.124A/V -0.4857142857142857 0.7999999999999999 False False False 2 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 2 8 HEDLIGKHG HEDLIGKPG NetMHC 44324.83 44121.0 0.995 NetMHC 76.0 73.0 140 0.179 NA NA NA NA NA NA 46893.38 47060.5 1.004 82.0 80.5 44121.0 44324.83 73.0 76.0 50000.0 49461.93 88.0 88.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.44285714285714295 -0.44285714285714295 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 1 9 SPVKEEEKT SPVKEEEKP NetMHC 44328.17 44474.7 1.003 NetMHC 76.0 77.0 185 0.038 NA NA NA NA NA NA 47164.085 47237.35 1.002 82.0 82.5 44474.7 44328.17 77.0 76.0 50000.0 50000.0 88.0 88.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -1.8 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 10 NA STGQGSGEK NA PickPocket 38565.12 NA NA NetMHC 76.0 NA 142 0.768 NA NA NA NA NA NA 41470.16 NA NA 78.5 NA NA 44375.2 NA 76.0 NA 38565.12 NA 81.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.842857142857143 -1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 2 8 PVKEEEKTQ PVKEEEKPQ NetMHC 44415.57 44629.45 1.005 NetMHC 77.0 79.0 185 0.038 NA NA NA NA NA NA 47207.785 47314.725 1.002 82.5 83.5 44629.45 44415.57 79.0 77.0 50000.0 50000.0 88.0 88.0 12.NEFH.ENST00000310624.6.missense.830P/T -3.2142857142857144 -2.1142857142857143 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 10 1, 2 LPLLLLLGA PLLLLLLGA PickPocket 43911.91 40708.92 0.927 NetMHC 77.0 65.0 101 0.891 NA NA NA NA NA NA 44188.5 42010.55 0.951 81.0 74.0 43312.18 44465.09 65.0 77.0 40708.92 43911.91 83.0 85.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.9142857142857146 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 8 2 NNLLTEEED NHLLTEEED PickPocket 24218.04 25289.19 1.044 PickPocket 62.0 64.0 30 0.1 NA NA NA NA NA NA 34343.73 34755.03 1.012 69.5 69.0 44220.87 44469.42 74.0 77.0 25289.19 24218.04 64.0 62.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 -1.0142857142857145 False False False 0 True 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 8 NA AGSTGQGSG NA PickPocket 36534.22 NA NA NetMHC 77.0 NA 142 0.768 NA NA NA NA NA NA 40512.88 NA NA 78.0 NA NA 44491.54 NA 77.0 NA 36534.22 NA 79.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 8 2 KTQEVKVKE KPQEVKVKE PickPocket 15044.73 32434.8 2.156 PickPocket 40.0 74.0 185 0.038 NA NA NA NA NA NA 29772.71 38574.645 1.296 59.0 77.0 44714.49 44500.69 80.0 78.0 32434.8 15044.73 74.0 40.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.4142857142857141 -1.014285714285714 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 3 7 EDLIGKHGG EDLIGKPGG NetMHC 44517.54 41865.85 0.94 NetMHC 78.0 53.0 140 0.179 NA NA NA NA NA NA 47258.77 27982.46 0.592 83.0 45.5 41865.85 44517.54 53.0 78.0 14099.07 50000.0 38.0 88.0 11.TPST2.ENST00000338754.4.missense.274P/H -3.172065784643304e-17 -3.172065784643304e-17 True False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 7 3 GNLFNCECD GNPFNCECD PickPocket 20589.91 6978.43 0.339 PickPocket 54.0 14.0 303 0.135 NA NA NA NA NA NA 32593.51 23905.65 0.733 66.5 29.5 40832.87 44597.11 45.0 79.0 6978.43 20589.91 14.0 54.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 5 5 LAGNLFNCE LAGNPFNCE NetMHC 44599.04 44220.39 0.992 NetMHC 79.0 74.0 303 0.135 NA NA NA NA NA NA 47299.52 44790.52 0.947 83.5 80.0 44220.39 44599.04 74.0 79.0 45360.65 50000.0 86.0 88.0 13.ELFN2.ENST00000402918.2.missense.186P/L -0.2571428571428572 0.6857142857142856 False False False 1 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 6 4 AGNLFNCEC AGNPFNCEC NetMHC 44606.25 39747.48 0.891 NetMHC 79.0 39.0 303 0.135 NA NA NA NA NA NA 44739.375 34908.22 0.78 82.0 55.0 39747.48 44606.25 39.0 79.0 30068.96 44872.5 71.0 85.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.5 False True False 2 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 1 9 DAVQGIANQ DAVQGIANE NetMHC 44623.17 44773.1 1.003 NetMHC 79.0 80.0 22 0.5 NA NA NA NA NA NA 47311.585 47386.55 1.002 83.5 84.0 44773.1 44623.17 80.0 79.0 50000.0 50000.0 88.0 88.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.0571428571428572 0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 9 1 HGGVSLSKI PGGVSLSKI PickPocket 37333.42 50000.0 1.339 NetMHC 79.0 84.0 140 0.179 NA NA NA NA NA NA 41005.35 47557.475 1.16 79.5 86.0 45114.95 44677.28 84.0 79.0 50000.0 37333.42 88.0 80.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.9428571428571428 0.9428571428571428 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 3 7 SYGLLHIYG SYGLLHTYG PickPocket 14882.82 50000.0 3.36 PickPocket 40.0 88.0 120 0.233 NA NA NA NA NA NA 29786.58 47512.115 1.595 60.0 85.5 45024.23 44690.34 83.0 80.0 50000.0 14882.82 88.0 40.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9714285714285714 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 9 NA GSTGQGSGE NA PickPocket 36534.22 NA NA PickPocket 79.0 NA 142 0.768 NA NA NA NA NA NA 40619.525 NA NA 79.5 NA NA 44704.83 NA 80.0 NA 36534.22 NA 79.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.3857142857142857 -1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 2 8 GGSHVWTHS GGSHVWTRS NetMHC 44814.29 44103.82 0.984 NetMHC 81.0 73.0 56 0.071 NA NA NA NA NA NA 47407.145 47051.91 0.993 84.5 80.5 44103.82 44814.29 73.0 81.0 50000.0 50000.0 88.0 88.0 5.CECR2.ENST00000262608.8.missense.535R/H -0.7714285714285714 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 2 8 LGWEFLAFT LGWEFLAST NetMHC 44815.74 45124.23 1.007 NetMHC 81.0 84.0 171 0.959 NA NA NA NA NA NA 46348.97 47562.115 1.026 84.0 86.0 45124.23 44815.74 84.0 81.0 50000.0 47882.2 88.0 87.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.8714285714285712 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 4 6 YGLLHIYGS YGLLHTYGS PickPocket 13797.25 11857.88 0.859 PickPocket 37.0 31.0 120 0.233 NA NA NA NA NA NA 29332.205 27633.815 0.942 59.0 48.5 43409.75 44867.16 66.0 81.0 11857.88 13797.25 31.0 37.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.914285714285714 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 8 2 PQTDYLTGT PETDYLTGT NetMHC 44982.35 45597.84 1.014 NetMHC 83.0 89.0 136 0.25 NA NA NA NA NA NA 47491.175 47798.92 1.006 85.5 88.5 45597.84 44982.35 89.0 83.0 50000.0 50000.0 88.0 88.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.5 -0.5 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 1 9 HHEDLIGKH HHEDLIGKP PickPocket 27575.71 30396.07 1.102 PickPocket 67.0 71.0 140 0.179 NA NA NA NA NA NA 36327.035 37807.795 1.041 75.5 78.0 45219.52 45078.36 85.0 84.0 30396.07 27575.71 71.0 67.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.8857142857142858 -0.7857142857142859 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 9 1 HSRDPEGSS RSRDPEGSS PickPocket 18679.43 15373.84 0.823 PickPocket 49.0 41.0 56 0.071 NA NA NA NA NA NA 31901.83 29645.73 0.929 66.5 56.0 43917.62 45124.23 71.0 84.0 15373.84 18679.43 41.0 49.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 11 1 PLLLLLGAS LLLLLLGAS NetMHC 45329.74 44996.48 0.993 NetMHC 87.0 83.0 101 0.891 NA NA NA NA NA NA 47664.87 47498.24 0.997 87.5 85.5 44996.48 45329.74 83.0 87.0 50000.0 50000.0 88.0 88.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.2571428571428567 2.9142857142857146 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 5 5 DDMDYLSDR DDMDCLSDR NetMHC 45692.66 45319.95 0.992 PickPocket 88.0 88.0 92 0.043 NA NA NA NA NA NA 47846.33 47659.975 0.996 89.0 87.0 45319.95 45692.66 86.0 90.0 50000.0 50000.0 88.0 88.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.1285714285714286 -0.9857142857142857 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 5 6, 9 SRTLLLAAA SRTLLAAAG PickPocket 41151.77 30726.73 0.747 PickPocket 83.0 72.0 76 0.158 NA NA NA NA NA NA 43565.535 37467.34 0.86 88.0 73.0 44207.95 45979.3 74.0 93.0 30726.73 41151.77 72.0 83.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.3000000000000003 2.3000000000000003 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 6 7 PLLPLLPLLL PLLPLLLLLL NetMHC 21178.51 26314.15 1.242 NetMHC 3.1 6.1 101 0.891 NA NA NA NA NA NA 27341.695 33511.535 1.226 19.05 25.55 26314.15 21178.51 6.1 3.1 40708.92 33504.88 45.0 35.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 4 7 QQRPGSAPTT QQRPGSSPTT PickPocket 11233.42 14564.23 1.297 PickPocket 3.5 6.8 7 0.571 NA NA NA NA NA NA 16726.485 20803.305 1.244 3.55 6.7 27042.38 22219.55 6.6 3.6 14564.23 11233.42 6.8 3.5 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5714285714285714 -0.5714285714285714 True False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 3 10 PPPPLLPLLP PPPPLLPLLL NetMHC 22226.29 21815.29 0.982 NetMHC 3.6 3.4 101 0.891 NA NA NA NA NA NA 36113.145 26777.875 0.741 30.3 17.7 21815.29 22226.29 3.4 3.6 31740.46 50000.0 32.0 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.4857142857142858 1.4857142857142858 False False True 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 3 9 ATLSRTLLLA ATLSRTLLAA PickPocket 11479.16 13356.59 1.164 NetMHC 3.6 41.0 76 0.158 NA NA NA NA NA NA 16856.685 26746.715 1.587 3.65 23.3 40136.84 22234.21 41.0 3.6 13356.59 11479.16 5.6 3.7 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0285714285714285 1.3142857142857143 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 2 10 SATLSRTLLL SATLSRTLLA PickPocket 21500.59 33144.32 1.542 NetMHC 3.9 43.0 76 0.158 NA NA NA NA NA NA 22233.185 36775.885 1.654 10.45 38.5 40407.45 22965.78 43.0 3.9 33144.32 21500.59 34.0 17.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.3142857142857143 1.3142857142857143 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 7 6, 10 LLPLLPLLLL LLPLLLLLLG PickPocket 5869.13 11233.42 1.914 PickPocket 0.6 3.5 101 0.891 NA NA NA NA NA NA 14482.245 18925.125 1.307 2.3 4.9 26616.83 23095.36 6.3 4.0 11233.42 5869.13 3.5 0.6 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 5 8 PPLLPLLPLL PPLLPLLLLL NetMHC 25069.88 30234.03 1.206 NetMHC 5.1 11.0 101 0.891 NA NA NA NA NA NA 37534.94 40117.015 1.069 31.05 34.0 30234.03 25069.88 11.0 5.1 50000.0 50000.0 57.0 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 2 9 VLCQRAKVEM VLCQRAKVAM PickPocket 18082.85 19295.7 1.067 NetMHC 5.4 5.7 113 0.044 NA NA NA NA NA NA 21734.13 22555.915 1.038 8.7 9.85 25816.13 25385.41 5.7 5.4 19295.7 18082.85 14.0 12.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.0714285714285712 0.0571428571428572 False False False 1 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 5 6 QRPGSAPTTV QRPGSSPTTV PickPocket 12517.05 12790.86 1.022 PickPocket 4.7 4.9 7 0.571 NA NA NA NA NA NA 18972.67 21250.11 1.12 5.05 7.15 29709.36 25428.29 9.4 5.4 12790.86 12517.05 4.9 4.7 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.2571428571428571 0.2571428571428571 True False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 8 1, 2, 4, 5 LPLLPLLLLL PLLPLLLLLL NetMHC 25501.86 26314.15 1.032 NetMHC 5.5 6.1 101 0.891 NA NA NA NA NA NA 34470.61 33511.535 0.972 27.25 25.55 26314.15 25501.86 6.1 5.5 40708.92 43439.36 45.0 49.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 2 9 YQPCDDMDYL YQPCDDMDCL PickPocket 5324.55 5560.06 1.044 PickPocket 0.5 0.5 92 0.043 NA NA NA NA NA NA 16636.515 18401.53 1.106 4.0 6.75 31243.0 27948.48 13.0 7.5 5560.06 5324.55 0.5 0.5 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.5142857142857142 -0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 10 1 ARPPQQPVPT PRPPQQPVPT PickPocket 7945.94 20368.33 2.563 PickPocket 1.5 15.0 245 0.486 NA NA NA NA NA NA 18001.285 26874.375 1.493 4.55 16.0 33380.42 28056.63 17.0 7.6 20368.33 7945.94 15.0 1.5 15.GGA1.ENST00000343632.4.missense.484P/A -1.1857142857142855 -1.1857142857142855 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 9 1, 3, 4 PLLPLLLLLG LLPLLLLLLG NetMHC 29821.75 26616.83 0.893 NetMHC 9.6 6.3 101 0.891 NA NA NA NA NA NA 39910.875 18925.125 0.474 33.3 4.9 26616.83 29821.75 6.3 9.6 11233.42 50000.0 3.5 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.4285714285714293 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 4 7 VRPLELVYCL VRPLELAYCL PickPocket 13212.86 14722.66 1.114 PickPocket 5.4 7.0 113 0.053 NA NA NA NA NA NA 21567.075 17943.6 0.832 7.55 5.05 21164.54 29921.29 3.1 9.7 14722.66 13212.86 7.0 5.4 6.USP18.ENST00000215794.7.missense.124A/V 1.9000000000000001 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 7 4 ALVRSRTYDM ALVHSRTYDM PickPocket 21040.32 19505.61 0.927 NetMHC 12.0 15.0 210 0.686 NA NA NA NA NA NA 25792.375 25978.1 1.007 14.0 14.5 32450.59 30544.43 15.0 12.0 19505.61 21040.32 14.0 16.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.9142857142857144 -0.09999999999999987 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 9 2 PARPPQQPVP PPRPPQQPVP NetMHC 31195.71 35499.65 1.138 NetMHC 13.0 22.0 245 0.486 NA NA NA NA NA NA 40597.855 42749.825 1.053 35.0 39.5 35499.65 31195.71 22.0 13.0 50000.0 50000.0 57.0 57.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 5 6 VSPEPARPPQ VSPEPPRPPQ PickPocket 6469.41 7054.34 1.09 PickPocket 0.8 1.0 245 0.486 NA NA NA NA NA NA 19811.53 20795.83 1.05 8.4 10.5 34537.32 33153.65 20.0 16.0 7054.34 6469.41 1.0 0.8 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -0.8571428571428571 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 5 6 LKFNPQTDYL LKFNPETDYL NetMHC 33452.35 33914.48 1.014 NetMHC 17.0 18.0 136 0.25 NA NA NA NA NA NA 41726.175 41957.24 1.006 37.0 37.5 33914.48 33452.35 18.0 17.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.4714285714285715 -0.942857142857143 False False False 0 False 1 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 1 10 LMVCELAGNL LMVCELAGNP PickPocket 18478.42 29108.61 1.575 PickPocket 13.0 28.0 303 0.135 NA NA NA NA NA NA 26084.345 36731.345 1.408 15.0 52.0 44354.08 33690.27 76.0 17.0 29108.61 18478.42 28.0 13.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6428571428571427 2.0714285714285716 False False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 10 1 YLSDRCKILQ CLSDRCKILQ PickPocket 9865.62 14407.49 1.46 PickPocket 2.5 6.7 92 0.043 NA NA NA NA NA NA 21824.125 23892.33 1.095 10.25 11.85 33377.17 33782.63 17.0 18.0 14407.49 9865.62 6.7 2.5 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.6571428571428573 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 9 2 DYLSDRCKIL DCLSDRCKIL NetMHC 34093.64 33762.52 0.99 NetMHC 18.0 18.0 92 0.043 NA NA NA NA NA NA 36965.55 41881.26 1.133 31.0 37.5 33762.52 34093.64 18.0 18.0 50000.0 39837.46 57.0 44.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857163 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 1 10 QKAVRPLELV QKAVRPLELA PickPocket 20589.91 20589.91 1.0 PickPocket 16.0 16.0 113 0.053 NA NA NA NA NA NA 27428.315 27419.975 1.0 17.5 17.5 34250.04 34266.72 19.0 19.0 20589.91 20589.91 16.0 16.0 6.USP18.ENST00000215794.7.missense.124A/V 0.9142857142857144 0.9142857142857144 True False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 10 1 TQKRNSRRQL AQKRNSRRQL PickPocket 28485.48 26985.39 0.947 NetMHC 19.0 23.0 96 0.042 NA NA NA NA NA NA 31406.16 31373.98 0.999 23.0 24.0 35762.57 34326.84 23.0 19.0 26985.39 28485.48 25.0 27.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -2.5 -2.5 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 6 5 KFNPQTDYLT KFNPETDYLT PickPocket 30068.96 33869.37 1.126 NetMHC 19.0 21.0 136 0.25 NA NA NA NA NA NA 32199.935 34522.025 1.072 24.5 28.0 35174.68 34330.91 21.0 19.0 33869.37 30068.96 35.0 30.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.0714285714285716 -1.0714285714285716 False False False 0 False 1 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 6 5 SPEPARPPQQ SPEPPRPPQQ PickPocket 15208.39 16946.23 1.114 PickPocket 7.6 9.8 245 0.486 NA NA NA NA NA NA 24932.195 22838.28 0.916 13.8 9.05 28730.33 34656.0 8.3 20.0 16946.23 15208.39 9.8 7.6 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -1.6857142857142855 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 8 3 LVRSRTYDMD LVHSRTYDMD PickPocket 27875.69 39837.46 1.429 NetMHC 21.0 21.0 210 0.686 NA NA NA NA NA NA 31472.54 37496.735 1.191 24.0 32.5 35156.01 35069.39 21.0 21.0 39837.46 27875.69 44.0 27.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.7714285714285716 -0.5428571428571428 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 9 2 HIYGSGGYAL HTYGSGGYAL PickPocket 22209.93 30396.07 1.369 PickPocket 18.0 30.0 120 0.233 NA NA NA NA NA NA 28776.8 34080.48 1.184 20.0 30.0 37764.89 35343.67 30.0 22.0 30396.07 22209.93 30.0 18.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.32857142857142857 0.32857142857142857 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 10 1 IYGSGGYALY TYGSGGYALY PickPocket 35367.39 44389.61 1.255 NetMHC 22.0 29.0 120 0.233 NA NA NA NA NA NA 35411.06 41002.825 1.158 30.0 39.5 37616.04 35454.73 29.0 22.0 44389.61 35367.39 50.0 38.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.1999999999999999 0.32857142857142857 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 2 9 ALGWEFLAFT ALGWEFLAST NetMHC 35835.78 43492.5 1.214 NetMHC 23.0 67.0 171 0.959 NA NA NA NA NA NA 40354.14 45687.35 1.132 37.0 60.5 43492.5 35835.78 67.0 23.0 47882.2 44872.5 54.0 51.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.8714285714285712 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 1 10 PALGWEFLAF PALGWEFLAS NetMHC 36280.14 44383.84 1.223 NetMHC 24.0 76.0 171 0.959 NA NA NA NA NA NA 43140.07 47191.92 1.094 40.5 66.5 44383.84 36280.14 76.0 24.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.9142857142857143 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 7 4 PEPARPPQQP PEPPRPPQQP PickPocket 23957.42 23444.56 0.979 PickPocket 21.0 20.0 245 0.486 NA NA NA NA NA NA 30238.71 27313.725 0.903 23.0 16.5 31182.89 36520.0 13.0 25.0 23444.56 23957.42 20.0 21.0 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -1.7999999999999996 False False True 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 1 10 SVLCQRAKVE SVLCQRAKVA NetMHC 36784.91 36890.12 1.003 NetMHC 26.0 26.0 113 0.044 NA NA NA NA NA NA 39647.18 42128.52 1.063 37.0 40.0 36890.12 36784.91 26.0 26.0 47366.92 42509.45 54.0 48.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.9857142857142857 0.4999999999999999 False False False 1 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 6 5 LIGKHGGVSL LIGKPGGVSL PickPocket 28485.48 31060.99 1.09 PickPocket 27.0 31.0 140 0.179 NA NA NA NA NA NA 32898.15 29744.755 0.904 27.5 19.5 28428.52 37310.82 8.0 28.0 31060.99 28485.48 31.0 27.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.10000000000000002 0.05714285714285713 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 4 7 VNEALNNLLT VNEALNHLLT PickPocket 21734.48 22942.68 1.056 PickPocket 17.0 19.0 30 0.1 NA NA NA NA NA NA 29954.06 29446.325 0.983 24.0 21.0 35949.97 38173.64 23.0 31.0 22942.68 21734.48 19.0 17.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.7857142857142856 0.7857142857142856 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 4 9 PPPLLPLLPL PPPLLPLLLL NetMHC 38950.93 37931.97 0.974 NetMHC 35.0 30.0 101 0.891 NA NA NA NA NA NA 43940.285 40220.71 0.915 45.5 39.0 37931.97 38950.93 30.0 35.0 42509.45 48929.64 48.0 56.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 3 8 SVNEALNNLL SVNEALNHLL NetMHC 38983.8 36348.9 0.932 NetMHC 35.0 25.0 30 0.1 NA NA NA NA NA NA 44491.9 43174.45 0.97 46.0 41.0 36348.9 38983.8 25.0 35.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.3857142857142856 0.3857142857142856 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 8 3 LAFTRLTSEL LASTRLTSEL NetMHC 39280.61 39267.87 1.0 NetMHC 36.0 36.0 171 0.959 NA NA NA NA NA NA 44640.305 44633.935 1.0 46.5 46.5 39267.87 39280.61 36.0 36.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.3714285714285715 0.8999999999999997 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 1 10 MYQPCDDMDY MYQPCDDMDC PickPocket 15881.05 15373.84 0.968 PickPocket 8.4 7.8 92 0.043 NA NA NA NA NA NA 27664.31 28174.62 1.018 22.7 26.9 40975.4 39447.57 46.0 37.0 15373.84 15881.05 7.8 8.4 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 NA NA NA NA -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-E*01:01 10 3 1 SAAAAAAAVI AAAAAAAAVI NetMHC 39812.46 39812.05 1.0 NetMHC 39.0 39.0 128 0.977 NA NA NA NA NA NA 41160.955 44107.57 1.072 43.5 47.0 39812.05 39812.46 39.0 39.0 48403.09 42509.45 55.0 48.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.5285714285714285 2.5285714285714285 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 2 9 KSVNEALNNL KSVNEALNHL PickPocket 18882.64 18882.64 1.0 PickPocket 13.0 13.0 30 0.1 NA NA NA NA NA NA 29403.2 29096.295 0.99 26.5 24.5 39309.95 39923.76 36.0 40.0 18882.64 18882.64 13.0 13.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 2 9 KAVRPLELVY KAVRPLELAY NetMHC 40129.47 43168.07 1.076 NetMHC 41.0 64.0 113 0.053 NA NA NA NA NA NA 41784.415 45525.135 1.09 45.0 59.0 43168.07 40129.47 64.0 41.0 47882.2 43439.36 54.0 49.0 6.USP18.ENST00000215794.7.missense.124A/V 0.1285714285714286 0.9142857142857144 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 3 8 AVRPLELVYC AVRPLELAYC PickPocket 37739.56 50000.0 1.325 NetMHC 41.0 59.0 113 0.053 NA NA NA NA NA NA 38969.275 46337.68 1.189 41.0 58.0 42675.36 40198.99 59.0 41.0 50000.0 37739.56 57.0 41.0 6.USP18.ENST00000215794.7.missense.124A/V 1.1285714285714286 1.1285714285714286 False True False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 9 2 VEMSHFEPNE VAMSHFEPNE PickPocket 31060.99 38984.65 1.255 PickPocket 31.0 43.0 113 0.044 NA NA NA NA NA NA 35669.175 39631.005 1.111 36.5 42.5 40277.36 40277.36 42.0 42.0 38984.65 31060.99 43.0 31.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.9000000000000001 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 1 10 LYYSYGLLHI LYYSYGLLHT PickPocket 20813.9 21269.21 1.022 PickPocket 16.0 17.0 120 0.233 NA NA NA NA NA NA 30597.35 32419.005 1.06 29.0 42.5 43568.8 40380.8 68.0 42.0 21269.21 20813.9 17.0 16.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9142857142857143 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 4 7 GWEFLAFTRL GWEFLASTRL PickPocket 32085.75 50000.0 1.558 PickPocket 33.0 57.0 171 0.959 NA NA NA NA NA NA 36257.755 46580.07 1.285 38.0 60.5 43160.14 40429.76 64.0 43.0 50000.0 32085.75 57.0 33.0 22.PANX2.ENST00000395842.2.missense.147S/F 1.4000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 7 4 PGSAPTTVIY PGSSPTTVIY NetMHC 40484.47 41890.78 1.035 NetMHC 43.0 53.0 7 0.571 NA NA NA NA NA NA 45242.235 45945.39 1.016 50.0 55.0 41890.78 40484.47 53.0 43.0 50000.0 50000.0 57.0 57.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.8857142857142858 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 8 3 GSAPTTVIYE GSSPTTVIYE PickPocket 13797.25 17888.25 1.297 PickPocket 6.1 12.0 7 0.571 NA NA NA NA NA NA 27146.555 29907.42 1.102 24.55 32.5 41926.59 40495.86 53.0 43.0 17888.25 13797.25 12.0 6.1 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.12857142857142861 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 9 2 NLFNCECDLF NPFNCECDLF NetMHC 40641.14 43932.84 1.081 NetMHC 44.0 71.0 303 0.135 NA NA NA NA NA NA 45320.57 46966.42 1.036 50.5 64.0 43932.84 40641.14 71.0 44.0 50000.0 50000.0 57.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 True 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 7 4 IGKHGGVSLS IGKPGGVSLS NetMHC 41231.54 33876.33 0.822 NetMHC 48.0 18.0 140 0.179 NA NA NA NA NA NA 45615.77 41938.165 0.919 52.5 37.5 33876.33 41231.54 18.0 48.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.3428571428571429 0.3428571428571429 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 4 7 TVSPEPARPP TVSPEPPRPP NetMHC 41372.32 40057.9 0.968 NetMHC 49.0 40.0 245 0.486 NA NA NA NA NA NA 45686.16 45028.95 0.986 53.0 48.5 40057.9 41372.32 40.0 49.0 50000.0 50000.0 57.0 57.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.7999999999999996 -0.31428571428571433 False False True 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 1 10 RVSLFGALVR RVSLFGALVH PickPocket 34610.27 31060.99 0.897 PickPocket 36.0 31.0 210 0.686 NA NA NA NA NA NA 37997.335 36054.125 0.949 42.5 39.0 41047.26 41384.4 47.0 49.0 31060.99 34610.27 31.0 36.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R 1.6428571428571428 2.1714285714285713 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 10 1 EMSHFEPNEY AMSHFEPNEY PickPocket 23957.42 14882.82 0.621 PickPocket 21.0 7.1 113 0.044 NA NA NA NA NA NA 32732.575 27673.35 0.845 35.5 25.05 40463.88 41507.73 43.0 50.0 14882.82 23957.42 7.1 21.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.9714285714285715 -1.1285714285714286 True False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 2 9 MVCELAGNLF MVCELAGNPF NetMHC 41580.55 44539.71 1.071 NetMHC 50.0 78.0 303 0.135 NA NA NA NA NA NA 45790.275 47269.855 1.032 53.5 67.5 44539.71 41580.55 78.0 50.0 50000.0 50000.0 57.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 1.4714285714285713 False False False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 7 4 FNPQTDYLTG FNPETDYLTG PickPocket 4676.23 4478.16 0.958 PickPocket 0.4 0.3 136 0.25 NA NA NA NA NA NA 23300.735 23574.685 1.012 26.7 29.65 42671.21 41925.24 59.0 53.0 4478.16 4676.23 0.3 0.4 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9000000000000001 -0.9000000000000001 False False False 0 False 1 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 2 9 VSLFGALVRS VSLFGALVHS PickPocket 24747.82 25564.3 1.033 PickPocket 22.0 23.0 210 0.686 NA NA NA NA NA NA 33359.445 33602.59 1.007 38.0 37.0 41640.88 41971.07 51.0 54.0 25564.3 24747.82 23.0 22.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R 0.9857142857142857 2.1714285714285713 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 4 8 TLSRTLLLAA TLSRTLLAAA PickPocket 23192.26 50000.0 2.156 PickPocket 20.0 57.0 76 0.158 NA NA NA NA NA NA 32641.01 47181.845 1.445 37.0 66.5 44363.69 42089.76 76.0 54.0 50000.0 23192.26 57.0 20.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.4 1.4 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 5 6 RPLELVYCLQ RPLELAYCLQ NetMHC 42220.2 38473.86 0.911 NetMHC 55.0 33.0 113 0.053 NA NA NA NA NA NA 46110.1 44236.93 0.959 56.0 45.0 38473.86 42220.2 33.0 55.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V 0.8571428571428571 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 8 3 GNLFNCECDL GNPFNCECDL PickPocket 33144.32 11233.42 0.339 PickPocket 34.0 3.5 303 0.135 NA NA NA NA NA NA 37709.695 26062.99 0.691 45.0 24.75 40892.56 42275.07 46.0 56.0 11233.42 33144.32 3.5 34.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 7 4 VWTHSRDPEG VWTRSRDPEG PickPocket 9759.45 10527.33 1.079 PickPocket 2.5 3.0 56 0.071 NA NA NA NA NA NA 26053.42 25969.75 0.997 29.75 26.0 41412.17 42347.39 49.0 57.0 10527.33 9759.45 3.0 2.5 5.CECR2.ENST00000262608.8.missense.535R/H -2.5 -1.3428571428571427 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 10 2, 3 LLPLLLLLGA LPLLLLLLGA PickPocket 12517.05 50000.0 3.995 PickPocket 4.7 57.0 101 0.891 NA NA NA NA NA NA 27532.575 48348.125 1.756 31.35 78.0 46696.25 42548.1 99.0 58.0 50000.0 12517.05 57.0 4.7 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.9142857142857146 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 9 2 AFTRLTSELN ASTRLTSELN NetMHC 42743.29 42913.81 1.004 PickPocket 57.0 57.0 171 0.959 NA NA NA NA NA NA 46371.645 46456.905 1.002 58.5 59.0 42913.81 42743.29 61.0 60.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.7714285714285715 0.24285714285714272 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 3 8 YQQRPGSAPT YQQRPGSSPT PickPocket 30396.07 45360.65 1.492 PickPocket 30.0 52.0 7 0.571 NA NA NA NA NA NA 36598.6 44398.125 1.213 45.0 59.0 43435.6 42801.13 66.0 60.0 45360.65 30396.07 52.0 30.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.1142857142857143 -1.1142857142857143 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 20 NA AGCPWSGTGQ NA NetMHC 42825.68 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 46412.84 NA NA 59.0 NA NA 42825.68 NA 61.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.1857142857142857 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-E*01:01 10 10 10 FNMSSFKLKQ FNMSSFKLKE PickPocket 12117.27 11986.87 0.989 PickPocket 4.3 4.1 117 0.496 NA NA NA NA NA NA 27491.41 27582.37 1.003 32.65 34.05 43177.87 42865.55 64.0 61.0 11986.87 12117.27 4.1 4.3 14.LGALS2.ENST00000215886.4.missense.132E/Q -0.9000000000000001 -0.07142857142857155 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 6 5 RPGSAPTTVI RPGSSPTTVI NetMHC 43044.0 43218.07 1.004 PickPocket 57.0 57.0 7 0.571 NA NA NA NA NA NA 46522.0 46609.035 1.002 60.0 60.5 43218.07 43044.0 64.0 63.0 50000.0 50000.0 57.0 57.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.9571428571428572 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 4 7 RTEASGYESR RTEASGSESR PickPocket 26407.71 35752.13 1.354 PickPocket 25.0 38.0 116 0.043 NA NA NA NA NA NA 34796.535 40332.24 1.159 44.5 60.0 44912.35 43185.36 82.0 64.0 35752.13 26407.71 38.0 25.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.3571428571428572 -1.2 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 4 7 VKEEEKTQEV VKEEEKPQEV NetMHC 43390.97 42201.47 0.973 PickPocket 57.0 29.0 185 0.038 NA NA NA NA NA NA 46695.485 35973.42 0.77 61.5 42.0 42201.47 43390.97 55.0 66.0 29745.37 50000.0 29.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.0571428571428574 -2.0571428571428574 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 3 8 VCELAGNLFN VCELAGNPFN PickPocket 26694.99 22942.68 0.859 PickPocket 25.0 19.0 303 0.135 NA NA NA NA NA NA 35048.62 32708.815 0.933 45.5 38.5 42474.95 43402.25 58.0 66.0 22942.68 26694.99 19.0 25.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 0.7000000000000001 False False False 1 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 9 2 SAPTTVIYED SSPTTVIYED PickPocket 19505.61 9146.01 0.469 PickPocket 14.0 2.1 7 0.571 NA NA NA NA NA NA 31458.155 26546.31 0.844 40.0 36.55 43946.61 43410.7 71.0 66.0 9146.01 19505.61 2.1 14.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.14285714285714274 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 21 NA GCPWSGTGQH NA PickPocket 25017.04 NA NA PickPocket 22.0 NA 142 0.768 NA NA NA NA NA NA 34217.385 NA NA 44.0 NA NA 43417.73 NA 66.0 NA 25017.04 NA 22.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.4142857142857141 -0.32857142857142857 False False False 1 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 4 7 CELAGNLFNC CELAGNPFNC PickPocket 35752.13 29425.27 0.823 PickPocket 38.0 29.0 303 0.135 NA NA NA NA NA NA 39609.85 35801.97 0.904 52.5 42.0 42178.67 43467.57 55.0 67.0 29425.27 35752.13 29.0 38.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.5 0.6857142857142856 True True False 2 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 5 6 ELAGNLFNCE ELAGNPFNCE NetMHC 43661.77 42762.7 0.979 PickPocket 57.0 45.0 303 0.135 NA NA NA NA NA NA 46830.885 41516.765 0.887 62.5 52.5 42762.7 43661.77 60.0 68.0 40270.83 50000.0 45.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L -0.2571428571428572 0.6857142857142856 True False False 1 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 7 4 IANQDAAQGI IANEDAAQGI NetMHC 43681.62 44133.41 1.01 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 46840.81 47066.705 1.005 63.0 65.0 44133.41 43681.62 73.0 69.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 -0.08571428571428576 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 9 2 VRSRTYDMDV VHSRTYDMDV PickPocket 36141.06 32787.64 0.907 PickPocket 39.0 34.0 210 0.686 NA NA NA NA NA NA 39917.95 37822.42 0.948 54.0 47.5 42857.2 43694.84 61.0 69.0 32787.64 36141.06 34.0 39.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 10 1 FTRLTSELNF STRLTSELNF PickPocket 11112.54 14099.07 1.269 PickPocket 3.4 6.4 171 0.959 NA NA NA NA NA NA 27418.825 28847.85 1.052 36.2 37.2 43596.63 43725.11 68.0 69.0 14099.07 11112.54 6.4 3.4 22.PANX2.ENST00000395842.2.missense.147S/F 0.27142857142857135 0.27142857142857135 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 1 10 LLHTVSPEPA LLHTVSPEPP PickPocket 32787.64 33504.88 1.022 PickPocket 34.0 35.0 245 0.486 NA NA NA NA NA NA 38265.13 38832.28 1.015 51.5 54.5 44159.68 43742.62 74.0 69.0 33504.88 32787.64 35.0 34.0 15.GGA1.ENST00000343632.4.missense.484P/A -0.31428571428571433 0.7857142857142857 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 3 8 ERTEASGYES ERTEASGSES NetMHC 43798.97 45557.39 1.04 PickPocket 54.0 57.0 116 0.043 NA NA NA NA NA NA 45582.945 47778.695 1.048 62.0 73.0 45557.39 43798.97 89.0 70.0 50000.0 47366.92 57.0 54.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2142857142857142 -1.2 True False False 0 False 0 NA NA NA NA -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-E*01:01 10 2 10 ASAAAAAAAV ASAAAAAAAA PickPocket 26985.39 26985.39 1.0 PickPocket 25.0 25.0 128 0.977 NA NA NA NA NA NA 35441.765 36055.29 1.017 48.0 54.5 45125.19 43898.14 84.0 71.0 26985.39 26985.39 25.0 25.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.142857142857143 2.142857142857143 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 3 8 LCQRAKVEMS LCQRAKVAMS PickPocket 30396.07 36141.06 1.189 PickPocket 30.0 39.0 113 0.044 NA NA NA NA NA NA 37196.79 40160.4 1.08 51.0 56.5 44179.74 43997.51 74.0 72.0 36141.06 30396.07 39.0 30.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.6857142857142857 0.0571428571428572 False False False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 4 7 CQRAKVEMSH CQRAKVAMSH PickPocket 11857.88 11986.87 1.011 PickPocket 4.0 4.1 113 0.044 NA NA NA NA NA NA 27935.795 26790.0 0.959 38.0 27.55 41593.13 44013.71 51.0 72.0 11986.87 11857.88 4.1 4.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.5 -0.5 True False False 1 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 9 2 TTQKRNSRRQ TAQKRNSRRQ NetMHC 44043.25 44115.25 1.002 PickPocket 51.0 57.0 96 0.042 NA NA NA NA NA NA 44457.875 47057.625 1.058 62.0 65.0 44115.25 44043.25 73.0 73.0 50000.0 44872.5 57.0 51.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6000000000000005 -2.5142857142857147 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 5 6 WEFLAFTRLT WEFLASTRLT NetMHC 44134.83 43136.32 0.977 PickPocket 57.0 57.0 171 0.959 NA NA NA NA NA NA 47067.415 46568.16 0.989 65.5 60.0 43136.32 44134.83 63.0 74.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.8999999999999997 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 7 4 DMDYLSDRCK DMDCLSDRCK NetMHC 44135.31 44483.36 1.008 PickPocket 50.0 44.0 92 0.043 NA NA NA NA NA NA 44262.46 42160.41 0.953 62.0 60.5 44483.36 44135.31 77.0 74.0 39837.46 44389.61 44.0 50.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.0999999999999999 -0.9857142857142857 False False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 3 8 QPCDDMDYLS QPCDDMDCLS NetMHC 44152.51 44358.89 1.005 PickPocket 57.0 57.0 92 0.043 NA NA NA NA NA NA 47076.255 47179.445 1.002 65.5 66.5 44358.89 44152.51 76.0 74.0 50000.0 50000.0 57.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142858 -0.5142857142857142 True False False 1 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 9 2 NQDAAQGIAK NEDAAQGIAK PickPocket 23957.42 50000.0 2.087 PickPocket 21.0 57.0 22 0.5 NA NA NA NA NA NA 34126.265 47742.985 1.399 48.0 72.5 45485.97 44295.11 88.0 75.0 50000.0 23957.42 57.0 21.0 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.3 0.35714285714285715 False False False 0 True 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 5 6 KEEEKTQEVK KEEEKPQEVK PickPocket 38150.11 39837.46 1.044 PickPocket 42.0 44.0 185 0.038 NA NA NA NA NA NA 41246.105 42644.25 1.034 59.0 66.0 45451.04 44342.1 88.0 76.0 39837.46 38150.11 44.0 42.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -2.0571428571428574 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 6 5 EFLAFTRLTS EFLASTRLTS NetMHC 44382.89 42983.5 0.968 PickPocket 52.0 30.0 171 0.959 NA NA NA NA NA NA 45118.5 36689.785 0.813 64.0 46.0 42983.5 44382.89 62.0 76.0 30396.07 45854.11 30.0 52.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.24285714285714272 1.4000000000000001 True False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 8 3 EPARPPQQPV EPPRPPQQPV NetMHC 44515.62 42220.2 0.948 PickPocket 57.0 57.0 245 0.486 NA NA NA NA NA NA 47257.81 46110.1 0.976 67.5 56.0 42220.2 44515.62 55.0 78.0 50000.0 50000.0 57.0 57.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.7285714285714289 -1.7285714285714289 True False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 9 2 GYESRVEPPH GSESRVEPPH PickPocket 11857.88 12382.34 1.044 PickPocket 4.0 4.5 116 0.043 NA NA NA NA NA NA 28224.36 28645.155 1.015 41.5 43.25 44907.97 44590.84 82.0 79.0 12382.34 11857.88 4.5 4.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285714 -1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 9 2 KHGGVSLSKI KPGGVSLSKI PickPocket 40270.83 50000.0 1.242 PickPocket 45.0 57.0 140 0.179 NA NA NA NA NA NA 42433.235 47907.215 1.129 62.0 74.5 45814.43 44595.64 92.0 79.0 50000.0 40270.83 57.0 45.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.9428571428571428 0.9428571428571428 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 7 4 LELVYCLQKC LELAYCLQKC NetMHC 44606.25 43419.16 0.973 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 47303.125 46709.58 0.987 68.0 61.5 43419.16 44606.25 66.0 79.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V 0.6142857142857141 1.9000000000000001 False True False 2 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 4 7 TLKFNPQTDY TLKFNPETDY NetMHC 44629.45 44915.24 1.006 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 47314.725 47457.62 1.003 68.0 69.5 44915.24 44629.45 82.0 79.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.6142857142857143 -0.942857142857143 False False False 0 False 1 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 9 1 LLLAAAGGSS TLLAAAGGSS NetMHC 44668.58 44213.23 0.99 PickPocket 56.0 57.0 76 0.158 NA NA NA NA NA NA 47065.255 47106.615 1.001 67.5 65.5 44213.23 44668.58 74.0 79.0 50000.0 49461.93 57.0 56.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 0.42857142857142855 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 3 8 HTVSPEPARP HTVSPEPPRP PickPocket 30396.07 11479.16 0.378 PickPocket 30.0 3.7 245 0.486 NA NA NA NA NA NA 37541.745 25889.6 0.69 55.0 22.85 40300.04 44687.42 42.0 80.0 11479.16 30396.07 3.7 30.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.6857142857142855 -0.31428571428571433 False False True 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 6 5 DDMDYLSDRC DDMDCLSDRC NetMHC 44694.69 45005.24 1.007 PickPocket 57.0 57.0 92 0.043 NA NA NA NA NA NA 47347.345 47502.62 1.003 68.5 70.0 45005.24 44694.69 83.0 80.0 50000.0 50000.0 57.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.042857142857143 -0.9857142857142857 False True False 1 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 8 1, 2 TLLLAAAGGS RTLLAAAGGS NetMHC 44709.19 44101.91 0.986 PickPocket 57.0 57.0 76 0.158 NA NA NA NA NA NA 47354.595 47050.955 0.994 68.5 65.0 44101.91 44709.19 73.0 80.0 50000.0 50000.0 57.0 57.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0857142857142856 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 16 NA SGEKAGCPWS NA PickPocket 17695.75 NA NA PickPocket 12.0 NA 142 0.768 NA NA NA NA NA NA 31212.865 NA NA 46.0 NA NA 44729.98 NA 80.0 NA 17695.75 NA 12.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 5 6 TEASGYESRV TEASGSESRV NetMHC 44831.75 44279.77 0.988 PickPocket 57.0 57.0 116 0.043 NA NA NA NA NA NA 47415.875 47139.885 0.994 69.0 66.0 44279.77 44831.75 75.0 81.0 50000.0 50000.0 57.0 57.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.0142857142857145 -1.0142857142857145 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 2 9 YYSYGLLHIY YYSYGLLHTY PickPocket 28485.48 31060.99 1.09 PickPocket 27.0 31.0 120 0.233 NA NA NA NA NA NA 36671.47 38407.99 1.047 54.0 61.0 45754.99 44857.46 91.0 81.0 31060.99 28485.48 31.0 27.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.8428571428571427 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 7 4 FLAFTRLTSE FLASTRLTSE PickPocket 16946.23 16404.99 0.968 PickPocket 9.8 9.1 171 0.959 NA NA NA NA NA NA 30903.54 30332.56 0.982 45.4 42.05 44260.13 44860.85 75.0 81.0 16404.99 16946.23 9.1 9.8 22.PANX2.ENST00000395842.2.missense.147S/F -0.5142857142857143 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 5 6 QRAKVEMSHF QRAKVAMSHF NetMHC 44892.89 41964.27 0.935 PickPocket 57.0 57.0 113 0.044 NA NA NA NA NA NA 47446.445 45982.135 0.969 69.5 55.0 41964.27 44892.89 53.0 82.0 50000.0 50000.0 57.0 57.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.35714285714285715 -0.35714285714285715 True False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 8 3 WTHSRDPEGS WTRSRDPEGS PickPocket 18679.43 13070.67 0.7 PickPocket 13.0 5.3 56 0.071 NA NA NA NA NA NA 31798.555 28806.885 0.906 47.5 41.65 44543.1 44917.68 78.0 82.0 13070.67 18679.43 5.3 13.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 8 3 ELVYCLQKCN ELAYCLQKCN NetMHC 45012.56 44080.44 0.979 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 47506.28 47040.22 0.99 70.0 65.0 44080.44 45012.56 73.0 83.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V -0.4857142857142857 0.8571428571428571 True False False 2 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 1 10 KSPVKEEEKT KSPVKEEEKP PickPocket 9550.53 10301.97 1.079 PickPocket 2.4 2.9 185 0.038 NA NA NA NA NA NA 27295.915 27934.855 1.023 42.7 45.95 45567.74 45041.3 89.0 83.0 10301.97 9550.53 2.9 2.4 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -1.8 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 8 3 KVEMSHFEPN KVAMSHFEPN PickPocket 33504.88 26407.71 0.788 PickPocket 35.0 25.0 113 0.044 NA NA NA NA NA NA 39274.79 35467.695 0.903 59.5 51.5 44527.68 45044.7 78.0 84.0 26407.71 33504.88 25.0 35.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 8 3 VTTQKRNSRR VTAQKRNSRR NetMHC 45051.53 44239.07 0.982 PickPocket 57.0 54.0 96 0.042 NA NA NA NA NA NA 47525.765 45802.995 0.964 70.5 64.5 44239.07 45051.53 75.0 84.0 47366.92 50000.0 54.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6 -1.8 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 1 10 REERTEASGY REERTEASGS NetMHC 45075.42 45985.26 1.02 PickPocket 57.0 57.0 116 0.043 NA NA NA NA NA NA 47537.71 47992.63 1.01 70.5 75.0 45985.26 45075.42 93.0 84.0 50000.0 50000.0 57.0 57.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.342857142857143 -1.342857142857143 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 10 1 VYCLQKCNVP AYCLQKCNVP NetMHC 45113.49 46140.27 1.023 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 47556.745 48070.135 1.011 70.5 76.0 46140.27 45113.49 95.0 84.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V -0.28571428571428564 0.6142857142857141 False False True 2 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 5 6 FGALVRSRTY FGALVHSRTY NetMHC 45120.79 46358.45 1.027 PickPocket 54.0 57.0 210 0.686 NA NA NA NA NA NA 46243.855 48179.225 1.042 69.0 77.0 46358.45 45120.79 97.0 84.0 50000.0 47366.92 57.0 54.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.5428571428571428 0.9857142857142857 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 3 8 LGWEFLAFTR LGWEFLASTR NetMHC 45137.88 46808.02 1.037 PickPocket 57.0 57.0 171 0.959 NA NA NA NA NA NA 47568.94 48404.01 1.018 71.0 78.5 46808.02 45137.88 100.0 85.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.35714285714285704 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 7 NA RSAGSTGQGS NA PickPocket 18082.85 NA NA PickPocket 12.0 NA 142 0.768 NA NA NA NA NA NA 31638.47 NA NA 48.5 NA NA 45194.09 NA 85.0 NA 18082.85 NA 12.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 10 1 QDAAQGIAKE EDAAQGIAKE PickPocket 38565.12 48403.09 1.255 PickPocket 42.0 55.0 22 0.5 NA NA NA NA NA NA 41886.455 47045.9 1.123 63.5 72.5 45688.71 45207.79 90.0 85.0 48403.09 38565.12 55.0 42.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.45714285714285713 0.35714285714285715 True False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 17 NA GEKAGCPWSG NA PickPocket 41151.77 NA NA PickPocket 46.0 NA 142 0.768 NA NA NA NA NA NA 43189.07 NA NA 65.5 NA NA 45226.37 NA 85.0 NA 41151.77 NA 46.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G 0.02857142857142855 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 2 9 LHTVSPEPAR LHTVSPEPPR PickPocket 14099.07 13947.35 0.989 PickPocket 6.4 6.2 245 0.486 NA NA NA NA NA NA 29680.345 29519.195 0.995 46.2 45.1 45091.04 45261.62 84.0 86.0 13947.35 14099.07 6.2 6.4 15.GGA1.ENST00000343632.4.missense.484P/A -0.8571428571428571 -0.2571428571428572 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 7 4 AKVEMSHFEP AKVAMSHFEP PickPocket 36931.66 32434.8 0.878 PickPocket 40.0 33.0 113 0.044 NA NA NA NA NA NA 41112.8 38296.515 0.931 63.0 53.5 44158.23 45293.94 74.0 86.0 32434.8 36931.66 33.0 40.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 -0.3000000000000001 False False True 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 6 5 ISCTGSSGSI ISCTRSSGSI NetMHC 45313.08 44344.96 0.979 PickPocket 57.0 40.0 5 1.0 NA NA NA NA NA NA 47656.54 40638.31 0.853 71.5 58.0 44344.96 45313.08 76.0 86.0 36931.66 50000.0 40.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.08571428571428566 0.5 False False False 1 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 10 1 LFNCECDLFG PFNCECDLFG PickPocket 32085.75 50000.0 1.558 PickPocket 33.0 57.0 303 0.135 NA NA NA NA NA NA 38706.515 48069.645 1.242 60.0 76.0 46139.29 45327.28 95.0 87.0 50000.0 32085.75 57.0 33.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.5999999999999999 0.5999999999999999 False False False 2 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 5 6 NEALNNLLTE NEALNHLLTE PickPocket 38150.11 34237.82 0.897 PickPocket 42.0 36.0 30 0.1 NA NA NA NA NA NA 41745.565 39734.295 0.952 64.5 61.0 45230.77 45341.02 86.0 87.0 34237.82 38150.11 36.0 42.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.02857142857142847 0.7857142857142856 False False False 0 True 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 8 3 ANQDAAQGIA ANEDAAQGIA PickPocket 30068.96 34610.27 1.151 PickPocket 30.0 36.0 22 0.5 NA NA NA NA NA NA 37713.575 40091.475 1.063 58.5 62.5 45572.68 45358.19 89.0 87.0 34610.27 30068.96 36.0 30.0 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.35714285714285715 0.35714285714285715 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 6 5 GALVRSRTYD GALVHSRTYD NetMHC 45397.0 46028.58 1.014 PickPocket 57.0 57.0 210 0.686 NA NA NA NA NA NA 47698.5 48014.29 1.007 72.0 75.5 46028.58 45397.0 94.0 87.0 50000.0 50000.0 57.0 57.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.5857142857142856 -0.05714285714285732 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 6 5 EEEKTQEVKV EEEKPQEVKV NetMHC 45446.62 43858.27 0.965 PickPocket 57.0 57.0 185 0.038 NA NA NA NA NA NA 47723.31 46929.135 0.983 72.5 64.0 43858.27 45446.62 71.0 88.0 50000.0 50000.0 57.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.014285714285714 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 1 10 RSGGSHVWTH RSGGSHVWTR PickPocket 17130.58 19088.05 1.114 PickPocket 10.0 14.0 56 0.071 NA NA NA NA NA NA 31300.65 32339.74 1.033 49.0 51.5 45591.43 45470.72 89.0 88.0 19088.05 17130.58 14.0 10.0 5.CECR2.ENST00000262608.8.missense.535R/H -0.7142857142857143 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 10 1 RSRTYDMDVR HSRTYDMDVR PickPocket 28485.48 34610.27 1.215 PickPocket 27.0 36.0 210 0.686 NA NA NA NA NA NA 36982.525 40470.075 1.094 57.5 66.0 46329.88 45479.57 96.0 88.0 34610.27 28485.48 36.0 27.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 6 6, 7, 8, 9, 10 GRSAGSTGQG GRSAGQHWAR NetMHC 45481.54 45609.19 1.003 PickPocket 57.0 54.0 142 0.768 NA NA NA NA NA NA 47740.77 46488.055 0.974 72.5 72.0 45609.19 45481.54 90.0 88.0 47366.92 50000.0 54.0 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6285714285714287 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 10 1 YESRVEPPHE SESRVEPPHE PickPocket 17316.93 22209.93 1.283 PickPocket 12.0 18.0 116 0.043 NA NA NA NA NA NA 31428.29 33787.995 1.075 50.5 52.5 45366.06 45539.65 87.0 89.0 22209.93 17316.93 18.0 12.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.957142857142857 -1.5714285714285712 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 10 1 HSRDPEGSSR RSRDPEGSSR NetMHC 45541.12 44587.93 0.979 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 47770.56 47293.965 0.99 73.0 67.5 44587.93 45541.12 78.0 89.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 4 7 VTISCTGSSG VTISCTRSSG NetMHC 45570.71 45036.92 0.988 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 47785.355 47518.46 0.994 73.0 70.0 45036.92 45570.71 83.0 89.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.19999999999999998 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 2 9 AGTLKFNPQT AGTLKFNPET PickPocket 21734.48 21970.92 1.011 PickPocket 17.0 18.0 136 0.25 NA NA NA NA NA NA 33658.015 33866.91 1.006 53.0 54.5 45762.9 45581.55 91.0 89.0 21970.92 21734.48 18.0 17.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 -0.0142857142857143 False False False 0 False 1 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 7 4 SCTGSSGSIA SCTRSSGSIA NetMHC 45586.99 45060.8 0.988 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 47793.495 47530.4 0.994 73.0 70.5 45060.8 45586.99 84.0 89.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.4428571428571428 0.4428571428571428 False False False 1 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 7 4 LLHIYGSGGY LLHTYGSGGY NetMHC 45587.96 45497.29 0.998 PickPocket 57.0 57.0 120 0.233 NA NA NA NA NA NA 47793.98 47748.645 0.999 73.0 72.5 45497.29 45587.96 88.0 89.0 50000.0 50000.0 57.0 57.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.014285714285714266 0.914285714285714 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 5 6 TVVVTTQKRN TVVVTAQKRN NetMHC 45654.6 45415.65 0.995 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 47827.3 47707.825 0.998 73.5 72.5 45415.65 45654.6 88.0 90.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -1.8 1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 8 3 MDYLSDRCKI MDCLSDRCKI PickPocket 44872.5 38150.11 0.85 PickPocket 51.0 42.0 92 0.043 NA NA NA NA NA NA 45267.745 42109.27 0.93 70.5 68.0 46068.43 45662.99 94.0 90.0 38150.11 44872.5 42.0 51.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857146 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 8 3 LHIYGSGGYA LHTYGSGGYA NetMHC 45670.41 45926.11 1.006 PickPocket 57.0 55.0 120 0.233 NA NA NA NA NA NA 47835.205 47164.6 0.986 73.5 74.0 45926.11 45670.41 93.0 90.0 48403.09 50000.0 55.0 57.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.39999999999999997 0.3142857142857142 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 3 8 TVTISCTGSS TVTISCTRSS NetMHC 45673.86 45093.48 0.987 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 47836.93 47546.74 0.994 73.5 70.5 45093.48 45673.86 84.0 90.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 1 10 QWYQQRPGSA QWYQQRPGSS NetMHC 45692.16 45897.8 1.005 PickPocket 52.0 52.0 7 0.571 NA NA NA NA NA NA 45773.135 45629.225 0.997 71.0 72.0 45897.8 45692.16 92.0 90.0 45360.65 45854.11 52.0 52.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.7857142857142858 -1.7857142857142858 True False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 4 7 VQGIANQDAA VQGIANEDAA NetMHC 45704.03 45900.29 1.004 PickPocket 56.0 54.0 22 0.5 NA NA NA NA NA NA 47582.98 46891.245 0.985 73.5 73.5 45900.29 45704.03 93.0 91.0 47882.2 49461.93 54.0 56.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.08571428571428576 -0.0571428571428572 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 5 6 DLIGKHGGVS DLIGKPGGVS NetMHC 45717.39 45725.29 1.0 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 47858.695 47862.645 1.0 74.0 74.0 45725.29 45717.39 91.0 91.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.7000000000000001 0.05714285714285713 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 7 1, 2, 3 RTLLLAAAGG SRTLLAAAGG NetMHC 45722.81 46525.27 1.018 PickPocket 57.0 57.0 76 0.158 NA NA NA NA NA NA 47861.405 48262.635 1.008 74.0 77.5 46525.27 45722.81 98.0 91.0 50000.0 50000.0 57.0 57.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.742857142857143 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 6 5 RAKVEMSHFE RAKVAMSHFE NetMHC 45723.31 45260.16 0.99 PickPocket 57.0 57.0 113 0.044 NA NA NA NA NA NA 47861.655 47630.08 0.995 74.0 71.5 45260.16 45723.31 86.0 91.0 50000.0 50000.0 57.0 57.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.3000000000000001 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 6 5 GIANQDAAQG GIANEDAAQG PickPocket 41599.44 47366.92 1.139 PickPocket 47.0 54.0 22 0.5 NA NA NA NA NA NA 43662.865 46625.405 1.068 69.0 73.0 45883.89 45726.29 92.0 91.0 47366.92 41599.44 54.0 47.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.5428571428571427 -0.08571428571428576 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 3 8 SLFGALVRSR SLFGALVHSR NetMHC 45865.01 45847.65 1.0 PickPocket 57.0 57.0 210 0.686 NA NA NA NA NA NA 47932.505 47923.825 1.0 74.5 74.5 45847.65 45865.01 92.0 92.0 50000.0 50000.0 57.0 57.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.05714285714285732 2.1714285714285713 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 3 8 GTLKFNPQTD GTLKFNPETD NetMHC 45866.52 46007.66 1.003 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 47933.26 48003.83 1.001 74.5 75.5 46007.66 45866.52 94.0 92.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.9857142857142855 -0.5000000000000001 False False False 0 False 1 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 1 10 SAKTTVVVTT SAKTTVVVTA NetMHC 45866.52 45867.5 1.0 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 47933.26 47933.75 1.0 74.5 74.5 45867.5 45866.52 92.0 92.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.4000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 18 NA EKAGCPWSGT NA NetMHC 45874.45 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 47937.225 NA NA 74.5 NA NA 45874.45 NA 92.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.32857142857142857 0.02857142857142855 True False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 19 NA KAGCPWSGTG NA NetMHC 45907.71 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 47953.855 NA NA 75.0 NA NA 45907.71 NA 93.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.3285714285714286 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 7 4 EEKTQEVKVK EEKPQEVKVK NetMHC 45921.63 43010.04 0.937 PickPocket 57.0 57.0 185 0.038 NA NA NA NA NA NA 47960.815 46505.02 0.97 75.0 59.5 43010.04 45921.63 62.0 93.0 50000.0 50000.0 57.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.0142857142857142 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 1 10 NKSVNEALNN NKSVNEALNH PickPocket 35752.13 36141.06 1.011 PickPocket 38.0 39.0 30 0.1 NA NA NA NA NA NA 40844.33 40807.62 0.999 65.5 63.5 45474.18 45936.53 88.0 93.0 36141.06 35752.13 39.0 38.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6 -0.21428571428571427 False False False 0 True 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 8 3 CTGSSGSIAS CTRSSGSIAS PickPocket 37333.42 26123.53 0.7 PickPocket 41.0 24.0 5 1.0 NA NA NA NA NA NA 41647.155 35751.175 0.858 67.0 55.5 45378.82 45960.89 87.0 93.0 26123.53 37333.42 24.0 41.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.38571428571428573 0.4428571428571428 True False False 1 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 10 1 NLLTEEEDYQ HLLTEEEDYQ NetMHC 45979.8 45998.7 1.0 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 47989.9 47999.35 1.0 75.0 75.0 45998.7 45979.8 93.0 93.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -2.7857142857142856 -1.0142857142857145 False False False 0 True 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 6 5 VVVTTQKRNS VVVTAQKRNS NetMHC 45979.8 45917.66 0.999 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 47989.9 47958.83 0.999 75.0 75.0 45917.66 45979.8 93.0 93.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -2.5142857142857147 0.5428571428571433 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 4 7 TTVVVTTQKR TTVVVTAQKR NetMHC 46004.18 45633.85 0.992 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 48002.09 47816.925 0.996 75.0 73.5 45633.85 46004.18 90.0 93.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -0.7000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 4 7 EDLIGKHGGV EDLIGKPGGV NetMHC 46038.55 45626.46 0.991 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 48019.275 47813.23 0.996 75.5 73.5 45626.46 46038.55 90.0 94.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.05714285714285713 0.05714285714285713 True False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 6 5 HVWTHSRDPE HVWTRSRDPE NetMHC 46043.51 45411.73 0.986 PickPocket 57.0 55.0 56 0.071 NA NA NA NA NA NA 48021.755 46907.41 0.977 75.5 71.0 45411.73 46043.51 87.0 94.0 48403.09 50000.0 55.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.5428571428571423 -1.3000000000000003 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 1 10 IAGTLKFNPQ IAGTLKFNPE NetMHC 46065.46 46172.24 1.002 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 48032.73 48086.12 1.001 75.5 76.0 46172.24 46065.46 95.0 94.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 1.1285714285714286 False False False 0 False 1 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 6 5 EASGYESRVE EASGSESRVE NetMHC 46065.94 45836.74 0.995 PickPocket 57.0 57.0 116 0.043 NA NA NA NA NA NA 48032.97 47918.37 0.998 75.5 74.5 45836.74 46065.94 92.0 94.0 50000.0 50000.0 57.0 57.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.4000000000000001 -1.0142857142857145 True False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 9 2 LVYCLQKCNV LAYCLQKCNV NetMHC 46072.92 46650.8 1.013 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 48036.46 48325.4 1.006 75.5 78.0 46650.8 46072.92 99.0 94.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V 0.3 0.7999999999999999 False False False 2 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 2 9 EERTEASGYE EERTEASGSE NetMHC 46097.35 46597.82 1.011 PickPocket 57.0 57.0 116 0.043 NA NA NA NA NA NA 48048.675 48298.91 1.005 75.5 77.5 46597.82 46097.35 98.0 94.0 50000.0 50000.0 57.0 57.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2 -1.2 True False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 6 5 PLELVYCLQK PLELAYCLQK NetMHC 46104.34 44922.05 0.974 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 48052.17 47461.025 0.988 75.5 69.5 44922.05 46104.34 82.0 94.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V 0.7999999999999999 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 8 3 NPQTDYLTGT NPETDYLTGT NetMHC 46148.75 46224.73 1.002 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 48074.375 48112.365 1.001 76.0 76.5 46224.73 46148.75 96.0 95.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.5 -0.5 False False False 0 True 1 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 7 4 ASGYESRVEP ASGSESRVEP NetMHC 46160.74 46090.87 0.998 PickPocket 54.0 49.0 116 0.043 NA NA NA NA NA NA 46763.83 44765.115 0.957 74.5 71.5 46090.87 46160.74 94.0 95.0 43439.36 47366.92 49.0 54.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285712 -1.0142857142857145 False False True 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 7 4 VVTTQKRNSR VVTAQKRNSR NetMHC 46171.22 45390.12 0.983 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 48085.61 47695.06 0.992 76.0 72.0 45390.12 46171.22 87.0 95.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.0571428571428574 -0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 9 2 NNLLTEEEDY NHLLTEEEDY NetMHC 46188.23 46243.73 1.001 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 48094.115 48121.865 1.001 76.0 76.5 46243.73 46188.23 96.0 95.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.742857142857143 -1.0142857142857145 False False False 0 True 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 10 1 TQEVKVKEPP PQEVKVKEPP PickPocket 31740.46 50000.0 1.575 PickPocket 32.0 57.0 185 0.038 NA NA NA NA NA NA 38965.835 48453.45 1.243 63.5 78.5 46906.9 46191.21 100.0 95.0 50000.0 31740.46 57.0 32.0 12.NEFH.ENST00000310624.6.missense.830P/T -0.8714285714285713 -0.8714285714285713 False False True 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 15 NA GSGEKAGCPW NA NetMHC 46215.22 NA NA PickPocket 54.0 NA 142 0.768 NA NA NA NA NA NA 46791.07 NA NA 74.5 NA NA 46215.22 NA 95.0 NA 47366.92 NA 54.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8571428571428574 -0.6714285714285715 False False False 1 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 8 3 SGYESRVEPP SGSESRVEPP PickPocket 38565.12 28795.36 0.747 PickPocket 42.0 28.0 116 0.043 NA NA NA NA NA NA 42393.915 37563.365 0.886 68.5 62.0 46331.37 46222.71 96.0 95.0 28795.36 38565.12 28.0 42.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.6142857142857143 -1.0142857142857145 False False True 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 3 8 AVQGIANQDA AVQGIANEDA NetMHC 46238.24 46398.59 1.003 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 48119.12 48199.295 1.002 76.5 77.0 46398.59 46238.24 97.0 96.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 9 2 KTQEVKVKEP KPQEVKVKEP PickPocket 37333.42 50000.0 1.339 PickPocket 41.0 57.0 185 0.038 NA NA NA NA NA NA 41811.355 48286.31 1.155 68.5 77.5 46572.62 46289.29 98.0 96.0 50000.0 37333.42 57.0 41.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.1428571428571428 -1.014285714285714 False False True 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 14 NA QGSGEKAGCP NA NetMHC 46295.8 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48147.9 NA NA 76.5 NA NA 46295.8 NA 96.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.6714285714285715 True False True 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 11 NA STGQGSGEKA NA NetMHC 46339.89 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48169.945 NA NA 76.5 NA NA 46339.89 NA 96.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.5285714285714287 -1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 5 6 SHVWTHSRDP SHVWTRSRDP PickPocket 39408.75 33504.88 0.85 PickPocket 44.0 35.0 56 0.071 NA NA NA NA NA NA 42883.09 39516.85 0.922 70.5 62.0 45528.82 46357.43 89.0 97.0 33504.88 39408.75 35.0 44.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1714285714285717 -0.7714285714285714 False False True 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 12 NA TGQGSGEKAG NA PickPocket 35752.13 NA NA PickPocket 38.0 NA 142 0.768 NA NA NA NA NA NA 41069.84 NA NA 67.5 NA NA 46387.55 NA 97.0 NA 35752.13 NA 38.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0857142857142859 -1.0857142857142859 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 8 3 EKTQEVKVKE EKPQEVKVKE NetMHC 46420.68 43870.12 0.945 PickPocket 57.0 28.0 185 0.038 NA NA NA NA NA NA 48210.34 36332.74 0.754 77.0 49.5 43870.12 46420.68 71.0 97.0 28795.36 50000.0 28.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.4142857142857141 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 2 9 WYQQRPGSAP WYQQRPGSSP PickPocket 41599.44 40270.83 0.968 PickPocket 47.0 45.0 7 0.571 NA NA NA NA NA NA 44017.095 43335.71 0.985 72.0 71.0 46400.59 46434.75 97.0 97.0 40270.83 41599.44 45.0 47.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.5142857142857142 -1.5142857142857142 False False True 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 3 8 PVKEEEKTQE PVKEEEKPQE NetMHC 46449.34 44377.11 0.955 PickPocket 57.0 57.0 185 0.038 NA NA NA NA NA NA 48224.67 47188.555 0.979 77.0 66.5 44377.11 46449.34 76.0 97.0 50000.0 50000.0 57.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T -3.1571428571428575 -2.1142857142857143 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 9 2 TGSSGSIASN TRSSGSIASN PickPocket 39408.75 31740.46 0.805 PickPocket 44.0 32.0 5 1.0 NA NA NA NA NA NA 42935.065 38870.08 0.905 70.5 62.5 45999.7 46461.38 93.0 97.0 31740.46 39408.75 32.0 44.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.0 0.4428571428571428 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 3 9, 10 GGGGRSAGST GGGGRSAGQH PickPocket 45854.11 42971.89 0.937 PickPocket 52.0 49.0 142 0.768 NA NA NA NA NA NA 46159.0 44620.815 0.967 74.5 72.5 46269.74 46463.89 96.0 97.0 42971.89 45854.11 49.0 52.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7285714285714285 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 5 6 CDDMDYLSDR CDDMDCLSDR NetMHC 46494.59 46546.91 1.001 PickPocket 57.0 57.0 92 0.043 NA NA NA NA NA NA 48247.295 48273.455 1.001 77.5 77.5 46546.91 46494.59 98.0 98.0 50000.0 50000.0 57.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.1285714285714286 -0.5142857142857142 True False False 1 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 9 2 THSRDPEGSS TRSRDPEGSS NetMHC 46502.62 46646.26 1.003 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 48251.31 48323.13 1.001 77.5 78.0 46646.26 46502.62 99.0 98.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 4 7 GSHVWTHSRD GSHVWTRSRD NetMHC 46515.22 46703.81 1.004 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 48257.61 48351.905 1.002 77.5 78.0 46703.81 46515.22 99.0 98.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H -1.3428571428571427 -0.7142857142857143 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 7 4 ALNNLLTEEE ALNHLLTEEE NetMHC 46523.27 46373.49 0.997 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 48261.635 48186.745 0.998 77.5 77.0 46373.49 46523.27 97.0 98.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.7857142857142856 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 10 1 GSSGSIASNY RSSGSIASNY NetMHC 46529.29 45208.76 0.972 PickPocket 57.0 49.0 5 1.0 NA NA NA NA NA NA 48264.645 44324.06 0.918 77.5 67.0 45208.76 46529.29 85.0 98.0 43439.36 50000.0 49.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.07142857142857147 0.4428571428571428 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 8 3 GKHGGVSLSK GKPGGVSLSK PickPocket 42051.98 14252.45 0.339 PickPocket 47.0 6.5 140 0.179 NA NA NA NA NA NA 44297.18 29644.19 0.669 72.5 44.75 45035.93 46542.38 83.0 98.0 14252.45 42051.98 6.5 47.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.24285714285714294 0.3428571428571429 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 4 7 PCDDMDYLSD PCDDMDCLSD NetMHC 46553.49 46635.64 1.002 PickPocket 57.0 57.0 92 0.043 NA NA NA NA NA NA 48276.745 48317.82 1.001 77.5 78.0 46635.64 46553.49 99.0 98.0 50000.0 50000.0 57.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142857 -0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 10 1 QTDYLTGTDG ETDYLTGTDG NetMHC 46570.09 46809.05 1.005 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 48285.045 48404.525 1.002 77.5 78.5 46809.05 46570.09 100.0 98.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.45714285714285713 -0.45714285714285713 True False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 5 6 TISCTGSSGS TISCTRSSGS NetMHC 46580.7 45839.73 0.984 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 48290.35 47919.865 0.992 77.5 74.5 45839.73 46580.7 92.0 98.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.20000000000000004 0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 1 10 LHHEDLIGKH LHHEDLIGKP NetMHC 46597.82 46811.07 1.005 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 48298.91 48405.535 1.002 77.5 78.5 46811.07 46597.82 100.0 98.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.8857142857142858 -0.18571428571428594 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 4 8, 9, 10 GGGRSAGSTG GGGRSAGQHW NetMHC 46599.84 46066.44 0.989 PickPocket 57.0 57.0 142 0.768 NA NA NA NA NA NA 48299.92 48033.22 0.994 77.5 75.5 46066.44 46599.84 94.0 98.0 50000.0 50000.0 57.0 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7285714285714286 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 2 9 SGGSHVWTHS SGGSHVWTRS NetMHC 46620.52 46687.16 1.001 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 48310.26 48343.58 1.001 77.5 78.0 46687.16 46620.52 99.0 98.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H -0.7714285714285714 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 6 5 EALNNLLTEE EALNHLLTEE NetMHC 46621.54 46581.18 0.999 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 48310.77 48290.59 1.0 77.5 77.5 46581.18 46621.54 98.0 98.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.7857142857142856 True False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 3 8 YSYGLLHIYG YSYGLLHTYG PickPocket 37333.42 50000.0 1.339 PickPocket 41.0 57.0 120 0.233 NA NA NA NA NA NA 41995.63 48525.875 1.155 70.0 78.5 47051.75 46657.84 100.0 99.0 50000.0 37333.42 57.0 41.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9714285714285714 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 1 10 EDAVQGIANQ EDAVQGIANE NetMHC 46663.41 46745.79 1.002 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 48331.705 48372.895 1.001 78.0 78.0 46745.79 46663.41 99.0 99.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.0571428571428572 0.7000000000000001 True False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 4 7 LFGALVRSRT LFGALVHSRT NetMHC 46689.18 46499.12 0.996 PickPocket 57.0 57.0 210 0.686 NA NA NA NA NA NA 48344.59 48249.56 0.998 78.0 77.5 46499.12 46689.18 98.0 99.0 50000.0 50000.0 57.0 57.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.09999999999999987 1.6428571428571428 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 3 8 KTTVVVTTQK KTTVVVTAQK NetMHC 46710.89 46790.82 1.002 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 48355.445 48395.41 1.001 78.0 78.5 46790.82 46710.89 100.0 99.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 0.5428571428571433 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 5 6 QGIANQDAAQ QGIANEDAAQ NetMHC 46711.4 46770.57 1.001 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 48355.7 48385.285 1.001 78.0 78.0 46770.57 46711.4 99.0 99.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.2285714285714284 -0.08571428571428576 True False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 2 9 DAVQGIANQD DAVQGIANED NetMHC 46716.95 46791.33 1.002 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 48358.475 48395.665 1.001 78.0 78.5 46791.33 46716.95 100.0 99.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.157142857142857 0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 9 2 PQTDYLTGTD PETDYLTGTD NetMHC 46719.99 46966.32 1.005 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 48359.995 48483.16 1.003 78.0 78.5 46966.32 46719.99 100.0 99.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9 -0.5 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 2 9 AKTTVVVTTQ AKTTVVVTAQ NetMHC 46755.38 46925.17 1.004 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 48377.69 48462.585 1.002 78.0 78.5 46925.17 46755.38 100.0 99.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.0000000000000002 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 8 NA SAGSTGQGSG NA NetMHC 46772.08 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48386.04 NA NA 78.0 NA NA 46772.08 NA 99.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 5 7, 8, 9, 10 GGRSAGSTGQ GGRSAGQHWA NetMHC 46800.93 46477.98 0.993 PickPocket 57.0 50.0 142 0.768 NA NA NA NA NA NA 48400.465 45433.795 0.939 78.5 74.0 46477.98 46800.93 98.0 100.0 44389.61 50000.0 50.0 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6857142857142857 -0.6857142857142857 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 2 10 TGGGGRSAGS TGGGGRSAGQ NetMHC 46819.68 46560.51 0.994 PickPocket 57.0 57.0 142 0.768 NA NA NA NA NA NA 48409.84 48280.255 0.997 78.5 77.5 46560.51 46819.68 98.0 100.0 50000.0 50000.0 57.0 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.7285714285714285 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 10 1 HGGVSLSKIE PGGVSLSKIE NetMHC 46821.21 46994.77 1.004 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 48410.605 48497.385 1.002 78.5 78.5 46994.77 46821.21 100.0 100.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.5 0.9428571428571428 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 6 5 GLLHIYGSGG GLLHTYGSGG NetMHC 46854.14 46658.87 0.996 PickPocket 57.0 57.0 120 0.233 NA NA NA NA NA NA 48427.07 48329.435 0.998 78.5 78.0 46658.87 46854.14 99.0 100.0 50000.0 50000.0 57.0 57.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.2857142857142857 0.9714285714285714 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 6 1, 2, 3, 4 SRTLLLAAAG LSRTLLAAAG NetMHC 46856.16 47029.36 1.004 PickPocket 57.0 57.0 76 0.158 NA NA NA NA NA NA 48428.08 48514.68 1.002 78.5 78.5 47029.36 46856.16 100.0 100.0 50000.0 50000.0 57.0 57.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.342857142857143 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 2 9 KTVTISCTGS KTVTISCTRS NetMHC 46903.33 46427.23 0.99 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 48451.665 48213.615 0.995 78.5 77.0 46427.23 46903.33 97.0 100.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5142857142857142 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 3 8 GGSHVWTHSR GGSHVWTRSR NetMHC 46925.69 47050.75 1.003 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 48462.845 48525.375 1.001 78.5 78.5 47050.75 46925.69 100.0 100.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H -1.3000000000000003 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 2 9 SPVKEEEKTQ SPVKEEEKPQ NetMHC 46927.2 47045.65 1.003 PickPocket 57.0 57.0 185 0.038 NA NA NA NA NA NA 48463.6 48522.825 1.001 78.5 78.5 47045.65 46927.2 100.0 100.0 50000.0 50000.0 57.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T -3.2142857142857144 -1.8 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 12 1 PLLLLLGASG LLLLLLGASG NetMHC 46938.88 46940.91 1.0 PickPocket 57.0 57.0 101 0.891 NA NA NA NA NA NA 48469.44 48470.455 1.0 78.5 78.5 46940.91 46938.88 100.0 100.0 50000.0 50000.0 57.0 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.6571428571428568 2.9142857142857146 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 13 NA GQGSGEKAGC NA NetMHC 46983.59 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48491.795 NA NA 78.5 NA NA 46983.59 NA 100.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6714285714285715 -0.6714285714285715 False True False 1 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 5 7, 10 LSRTLLLAAA LSRTLLAAAG NetMHC 46989.19 47029.36 1.001 PickPocket 57.0 57.0 76 0.158 NA NA NA NA NA NA 48494.595 48514.68 1.0 78.5 78.5 47029.36 46989.19 100.0 100.0 50000.0 50000.0 57.0 57.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.3000000000000003 2.3000000000000003 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 9 NA AGSTGQGSGE NA NetMHC 47084.35 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48542.175 NA NA 78.5 NA NA 47084.35 NA 100.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.3857142857142857 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 10 1 APTTVIYEDN SPTTVIYEDN NetMHC 47145.52 47266.07 1.003 PickPocket 57.0 57.0 7 0.571 NA NA NA NA NA NA 48572.76 48633.035 1.001 78.5 78.5 47266.07 47145.52 100.0 100.0 50000.0 50000.0 57.0 57.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5428571428571428 0.8857142857142858 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 7 4 AGNLFNCECD AGNPFNCECD NetMHC 47175.62 45625.46 0.967 PickPocket 57.0 57.0 303 0.135 NA NA NA NA NA NA 48587.81 47812.73 0.984 78.5 73.5 45625.46 47175.62 90.0 100.0 50000.0 50000.0 57.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.5 False False False 2 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 5 6 YGLLHIYGSG YGLLHTYGSG NetMHC 47180.22 46813.61 0.992 PickPocket 57.0 57.0 120 0.233 NA NA NA NA NA NA 48590.11 48406.805 0.996 78.5 78.5 46813.61 47180.22 100.0 100.0 50000.0 50000.0 57.0 57.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.3142857142857142 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 6 5 LAGNLFNCEC LAGNPFNCEC NetMHC 47185.85 45731.25 0.969 PickPocket 57.0 57.0 303 0.135 NA NA NA NA NA NA 48592.925 47865.625 0.985 78.5 74.0 45731.25 47185.85 91.0 100.0 50000.0 50000.0 57.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.6857142857142856 False True False 2 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 1 10 GKTVTISCTG GKTVTISCTR NetMHC 47197.08 47039.55 0.997 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 48598.54 48519.775 0.998 78.5 78.5 47039.55 47197.08 100.0 100.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 1.2285714285714284 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 8 3 LNNLLTEEED LNHLLTEEED NetMHC 47229.26 47089.97 0.997 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 48614.63 48544.985 0.999 78.5 78.5 47089.97 47229.26 100.0 100.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.02857142857142847 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 10 NA GSTGQGSGEK NA NetMHC 47242.55 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48621.275 NA NA 78.5 NA NA 47242.55 NA 100.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.842857142857143 -1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 3 8 HEDLIGKHGG HEDLIGKPGG NetMHC 47290.1 46578.17 0.985 PickPocket 57.0 52.0 140 0.179 NA NA NA NA NA NA 48645.05 45969.41 0.945 78.5 75.0 46578.17 47290.1 98.0 100.0 45360.65 50000.0 52.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H -3.172065784643304e-17 -3.172065784643304e-17 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 4 7 SYGLLHIYGS SYGLLHTYGS PickPocket 42509.45 50000.0 1.176 PickPocket 48.0 57.0 120 0.233 NA NA NA NA NA NA 44914.875 48439.235 1.078 74.0 78.5 46878.47 47320.3 100.0 100.0 50000.0 42509.45 57.0 48.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.914285714285714 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 2 9 HHEDLIGKHG HHEDLIGKPG NetMHC 47320.82 47279.36 0.999 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 48660.41 48639.68 1.0 78.5 78.5 47279.36 47320.82 100.0 100.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.44285714285714295 -0.44285714285714295 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 11 1, 2 LPLLLLLGAS PLLLLLLGAS NetMHC 47327.99 47032.43 0.994 PickPocket 57.0 57.0 101 0.891 NA NA NA NA NA NA 48663.995 48516.215 0.997 78.5 78.5 47032.43 47327.99 100.0 100.0 50000.0 50000.0 57.0 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.2571428571428567 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 5 5 KFNPQTDYL KFNPETDYL PickPocket 1262.76 1318.61 1.044 PickPocket 0.5 0.6 136 0.25 NA NA NA NA NA NA 1262.76 1318.61 1.044 0.5 0.6 NA NA NA NA 1318.61 1262.76 0.6 0.5 19.ACO2.ENST00000216254.4.missense.510E/Q -1.4714285714285715 -1.4714285714285715 False False False 0 False 1 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 8 2 HIYGSGGYA HTYGSGGYA PickPocket 1672.99 1584.89 0.947 PickPocket 1.0 0.9 120 0.233 NA NA NA NA NA NA 1672.99 1584.89 0.947 1.0 0.9 NA NA NA NA 1584.89 1672.99 0.9 1.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.39999999999999997 -0.014285714285714266 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 1 9 WYQQRPGSA WYQQRPGSS PickPocket 2781.92 3567.97 1.283 PickPocket 2.7 4.3 7 0.571 NA NA NA NA NA NA 2781.92 3567.97 1.283 2.7 4.3 NA NA NA NA 3567.97 2781.92 4.3 2.7 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.7857142857142858 -1.7857142857142858 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 8 2 LVYCLQKCN LAYCLQKCN PickPocket 3099.81 6399.79 2.065 PickPocket 3.3 12.0 113 0.053 NA NA NA NA NA NA 3099.81 6399.79 2.065 3.3 12.0 NA NA NA NA 6399.79 3099.81 12.0 3.3 6.USP18.ENST00000215794.7.missense.124A/V -0.4857142857142857 0.7999999999999999 False False False 2 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 1 9 MVCELAGNL MVCELAGNP PickPocket 3454.02 10191.11 2.951 PickPocket 4.1 21.0 303 0.135 NA NA NA NA NA NA 3454.02 10191.11 2.951 4.1 21.0 NA NA NA NA 10191.11 3454.02 21.0 4.1 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6428571428571427 1.4714285714285713 False False False 1 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 2 8 YSYGLLHIY YSYGLLHTY PickPocket 3766.31 2842.78 0.755 PickPocket 4.7 2.8 120 0.233 NA NA NA NA NA NA 3766.31 2842.78 0.755 4.7 2.8 NA NA NA NA 2842.78 3766.31 2.8 4.7 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.8428571428571427 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 8 2 AFTRLTSEL ASTRLTSEL PickPocket 3807.28 8387.64 2.203 PickPocket 4.8 16.0 171 0.959 NA NA NA NA NA NA 3807.28 8387.64 2.203 4.8 16.0 NA NA NA NA 8387.64 3807.28 16.0 4.8 22.PANX2.ENST00000395842.2.missense.147S/F -0.3714285714285715 0.24285714285714272 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 2 9 ATLSRTLLL ATLSRTLLA PickPocket 4478.16 9245.51 2.065 PickPocket 6.1 19.0 76 0.158 NA NA NA NA NA NA 4478.16 9245.51 2.065 6.1 19.0 NA NA NA NA 9245.51 4478.16 19.0 6.1 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.3142857142857143 1.3142857142857143 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 6 4 LLHIYGSGG LLHTYGSGG PickPocket 4526.88 3932.89 0.869 PickPocket 6.3 5.0 120 0.233 NA NA NA NA NA NA 4526.88 3932.89 0.869 6.3 5.0 NA NA NA NA 3932.89 4526.88 5.0 6.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.2857142857142857 0.914285714285714 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 9 1 RSRTYDMDV HSRTYDMDV PickPocket 4576.12 7609.38 1.663 PickPocket 6.3 15.0 210 0.686 NA NA NA NA NA NA 4576.12 7609.38 1.663 6.3 15.0 NA NA NA NA 7609.38 4576.12 15.0 6.3 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 6 6 LLPLLPLLL LLPLLLLLL PickPocket 4778.52 4830.5 1.011 PickPocket 6.8 6.9 101 0.891 NA NA NA NA NA NA 4778.52 4830.5 1.011 6.8 6.9 NA NA NA NA 4830.5 4778.52 6.9 6.8 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 2 8 SVNEALNNL SVNEALNHL PickPocket 4989.87 7775.84 1.558 PickPocket 7.3 15.0 30 0.1 NA NA NA NA NA NA 4989.87 7775.84 1.558 7.3 15.0 NA NA NA NA 7775.84 4989.87 15.0 7.3 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 1 9 YYSYGLLHI YYSYGLLHT PickPocket 5382.48 8664.37 1.61 PickPocket 8.0 17.0 120 0.233 NA NA NA NA NA NA 5382.48 8664.37 1.61 8.0 17.0 NA NA NA NA 8664.37 5382.48 17.0 8.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9142857142857143 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 7 3 WTHSRDPEG WTRSRDPEG PickPocket 5500.22 19932.31 3.624 PickPocket 8.4 40.0 56 0.071 NA NA NA NA NA NA 5500.22 19932.31 3.624 8.4 40.0 NA NA NA NA 19932.31 5500.22 40.0 8.4 5.CECR2.ENST00000262608.8.missense.535R/H -2.5 -2.1714285714285717 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 3 7 SYGLLHIYG SYGLLHTYG PickPocket 5620.54 5743.49 1.022 PickPocket 8.7 9.0 120 0.233 NA NA NA NA NA NA 5620.54 5743.49 1.022 8.7 9.0 NA NA NA NA 5743.49 5620.54 9.0 8.7 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9714285714285714 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 9 1 IYGSGGYAL TYGSGGYAL PickPocket 5620.54 6539.79 1.164 PickPocket 8.7 12.0 120 0.233 NA NA NA NA NA NA 5620.54 6539.79 1.164 8.7 12.0 NA NA NA NA 6539.79 5620.54 12.0 8.7 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.32857142857142857 0.32857142857142857 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 8 2 GYESRVEPP GSESRVEPP PickPocket 5620.54 22209.93 3.952 PickPocket 8.7 44.0 116 0.043 NA NA NA NA NA NA 5620.54 22209.93 3.952 8.7 44.0 NA NA NA NA 22209.93 5620.54 44.0 8.7 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.6142857142857143 -1.4000000000000001 False False True 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 7 3 ANQDAAQGI ANEDAAQGI PickPocket 5681.68 9654.43 1.699 PickPocket 8.8 20.0 22 0.5 NA NA NA NA NA NA 5681.68 9654.43 1.699 8.8 20.0 NA NA NA NA 9654.43 5681.68 20.0 8.8 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 -0.4000000000000001 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 9 1 VYCLQKCNV AYCLQKCNV PickPocket 5932.98 4830.5 0.814 PickPocket 9.4 6.9 113 0.053 NA NA NA NA NA NA 5932.98 4830.5 0.814 9.4 6.9 NA NA NA NA 4830.5 5932.98 6.9 9.4 6.USP18.ENST00000215794.7.missense.124A/V 0.3 0.6142857142857141 False False False 2 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 3 7 GSHVWTHSR GSHVWTRSR PickPocket 6195.39 6399.79 1.033 PickPocket 9.9 12.0 56 0.071 NA NA NA NA NA NA 6195.39 6399.79 1.033 9.9 12.0 NA NA NA NA 6399.79 6195.39 12.0 9.9 5.CECR2.ENST00000262608.8.missense.535R/H -1.3000000000000003 -0.7142857142857143 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 8 2 NLFNCECDL NPFNCECDL PickPocket 6195.39 20813.9 3.36 PickPocket 9.9 42.0 303 0.135 NA NA NA NA NA NA 6195.39 20813.9 3.36 9.9 42.0 NA NA NA NA 20813.9 6195.39 42.0 9.9 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 True 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 4 6 RPLELVYCL RPLELAYCL PickPocket 6399.79 6903.33 1.079 PickPocket 12.0 13.0 113 0.053 NA NA NA NA NA NA 6399.79 6903.33 1.079 12.0 13.0 NA NA NA NA 6903.33 6399.79 13.0 12.0 6.USP18.ENST00000215794.7.missense.124A/V 1.9000000000000001 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 3 7 RTEASGYES RTEASGSES PickPocket 6399.79 5267.25 0.823 PickPocket 12.0 7.9 116 0.043 NA NA NA NA NA NA 6399.79 5267.25 0.823 12.0 7.9 NA NA NA NA 5267.25 6399.79 7.9 12.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2142857142857142 -1.2 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 7 3 SGYESRVEP SGSESRVEP PickPocket 7287.08 50000.0 6.861 PickPocket 14.0 73.0 116 0.043 NA NA NA NA NA NA 7287.08 50000.0 6.861 14.0 73.0 NA NA NA NA 50000.0 7287.08 73.0 14.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285712 -1.0142857142857145 False False True 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 8 2 KTQEVKVKE KPQEVKVKE PickPocket 7366.35 25842.4 3.508 PickPocket 14.0 50.0 185 0.038 NA NA NA NA NA NA 7366.35 25842.4 3.508 14.0 50.0 NA NA NA NA 25842.4 7366.35 50.0 14.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.4142857142857141 -1.014285714285714 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 2 8 AVQGIANQD AVQGIANED PickPocket 7609.38 5743.49 0.755 PickPocket 15.0 9.0 22 0.5 NA NA NA NA NA NA 7609.38 5743.49 0.755 15.0 9.0 NA NA NA NA 5743.49 7609.38 9.0 15.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.157142857142857 0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 3 7 VNEALNNLL VNEALNHLL PickPocket 7775.84 8032.38 1.033 PickPocket 15.0 16.0 30 0.1 NA NA NA NA NA NA 7775.84 8032.38 1.033 15.0 16.0 NA NA NA NA 8032.38 7775.84 16.0 15.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.3857142857142856 0.3857142857142856 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 9 1 LFNCECDLF PFNCECDLF PickPocket 7860.43 21500.59 2.735 PickPocket 15.0 43.0 303 0.135 NA NA NA NA NA NA 7860.43 21500.59 2.735 15.0 43.0 NA NA NA NA 21500.59 7860.43 43.0 15.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 5 5 HVWTHSRDP HVWTRSRDP PickPocket 8119.76 11112.54 1.369 PickPocket 16.0 23.0 56 0.071 NA NA NA NA NA NA 8119.76 11112.54 1.369 16.0 23.0 NA NA NA NA 11112.54 8119.76 23.0 16.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1714285714285717 -1.3000000000000003 False False True 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 6 1, 2, 3 RTLLLAAAG SRTLLAAAG PickPocket 8478.89 50000.0 5.897 PickPocket 17.0 73.0 76 0.158 NA NA NA NA NA NA 8478.89 50000.0 5.897 17.0 73.0 NA NA NA NA 50000.0 8478.89 73.0 17.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.342857142857143 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 1 9 YQPCDDMDY YQPCDDMDC PickPocket 8571.13 8478.89 0.989 PickPocket 17.0 17.0 92 0.043 NA NA NA NA NA NA 8571.13 8478.89 0.989 17.0 17.0 NA NA NA NA 8478.89 8571.13 17.0 17.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 5 5 EFLAFTRLT EFLASTRLT PickPocket 9146.01 11479.16 1.255 PickPocket 18.0 24.0 171 0.959 NA NA NA NA NA NA 9146.01 11479.16 1.255 18.0 24.0 NA NA NA NA 11479.16 9146.01 24.0 18.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.8999999999999997 1.4000000000000001 True False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 4 6 KEEEKTQEV KEEEKPQEV PickPocket 9346.08 11355.63 1.215 PickPocket 19.0 24.0 185 0.038 NA NA NA NA NA NA 9346.08 11355.63 1.215 19.0 24.0 NA NA NA NA 11355.63 9346.08 24.0 19.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.0571428571428574 -2.0571428571428574 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 1 9 KTVTISCTG KTVTISCTR PickPocket 9447.76 15208.39 1.61 PickPocket 19.0 31.0 5 1.0 NA NA NA NA NA NA 9447.76 15208.39 1.61 19.0 31.0 NA NA NA NA 15208.39 9447.76 31.0 19.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 1.2285714285714284 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 3 7 GWEFLAFTR GWEFLASTR PickPocket 9654.43 7775.84 0.805 PickPocket 20.0 15.0 171 0.959 NA NA NA NA NA NA 9654.43 7775.84 0.805 20.0 15.0 NA NA NA NA 7775.84 9654.43 15.0 20.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.35714285714285704 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 8 2 DYLSDRCKI DCLSDRCKI PickPocket 9865.62 50000.0 5.068 PickPocket 20.0 73.0 92 0.043 NA NA NA NA NA NA 9865.62 50000.0 5.068 20.0 73.0 NA NA NA NA 50000.0 9865.62 73.0 20.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857146 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 8 2 SAPTTVIYE SSPTTVIYE PickPocket 9972.95 5620.54 0.564 PickPocket 21.0 8.7 7 0.571 NA NA NA NA NA NA 9972.95 5620.54 0.564 21.0 8.7 NA NA NA NA 5620.54 9972.95 8.7 21.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.12857142857142861 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 2 8 LCQRAKVEM LCQRAKVAM PickPocket 9972.95 15710.15 1.575 PickPocket 21.0 33.0 113 0.044 NA NA NA NA NA NA 9972.95 15710.15 1.575 21.0 33.0 NA NA NA NA 15710.15 9972.95 33.0 21.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.0714285714285712 0.0571428571428572 False False False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 7 3 KVEMSHFEP KVAMSHFEP PickPocket 9972.95 31060.99 3.115 PickPocket 21.0 56.0 113 0.044 NA NA NA NA NA NA 9972.95 31060.99 3.115 21.0 56.0 NA NA NA NA 31060.99 9972.95 56.0 21.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 -0.3000000000000001 False False True 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 5 5 GLLHIYGSG GLLHTYGSG PickPocket 10414.04 12117.27 1.164 PickPocket 22.0 25.0 120 0.233 NA NA NA NA NA NA 10414.04 12117.27 1.164 22.0 25.0 NA NA NA NA 12117.27 10414.04 25.0 22.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.3142857142857142 0.9714285714285714 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 5 7 PLLPLLPLL PLLPLLLLL PickPocket 10527.33 12653.21 1.202 PickPocket 22.0 26.0 101 0.891 NA NA NA NA NA NA 10527.33 12653.21 1.202 22.0 26.0 NA NA NA NA 12653.21 10527.33 26.0 22.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 7 3 LVRSRTYDM LVHSRTYDM PickPocket 10527.33 2904.96 0.276 PickPocket 22.0 2.9 210 0.686 NA NA NA NA NA NA 10527.33 2904.96 0.276 22.0 2.9 NA NA NA NA 2904.96 10527.33 2.9 22.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.9142857142857144 -0.5428571428571428 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 2 8 KTTVVVTTQ KTTVVVTAQ PickPocket 10874.65 16763.86 1.542 PickPocket 23.0 34.0 96 0.042 NA NA NA NA NA NA 10874.65 16763.86 1.542 23.0 34.0 NA NA NA NA 16763.86 10874.65 34.0 23.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.0000000000000002 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 7 3 MDYLSDRCK MDCLSDRCK PickPocket 11355.63 50000.0 4.403 PickPocket 24.0 73.0 92 0.043 NA NA NA NA NA NA 11355.63 50000.0 4.403 24.0 73.0 NA NA NA NA 50000.0 11355.63 73.0 24.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.0999999999999999 -1.042857142857143 False False False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 9 1 QTDYLTGTD ETDYLTGTD PickPocket 11355.63 18882.64 1.663 PickPocket 24.0 38.0 136 0.25 NA NA NA NA NA NA 11355.63 18882.64 1.663 24.0 38.0 NA NA NA NA 18882.64 11355.63 38.0 24.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9 -0.5 True False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 2 8 LGWEFLAFT LGWEFLAST PickPocket 11730.27 17316.93 1.476 PickPocket 24.0 36.0 171 0.959 NA NA NA NA NA NA 11730.27 17316.93 1.476 24.0 36.0 NA NA NA NA 17316.93 11730.27 36.0 24.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.8714285714285712 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 2 8 GTLKFNPQT GTLKFNPET PickPocket 11986.87 9047.59 0.755 PickPocket 25.0 18.0 136 0.25 NA NA NA NA NA NA 11986.87 9047.59 0.755 25.0 18.0 NA NA NA NA 9047.59 11986.87 18.0 25.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 -0.5000000000000001 False False False 0 False 1 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 8 1 LLLAAAGGS TLLAAAGGS PickPocket 12517.05 12653.21 1.011 PickPocket 26.0 26.0 76 0.158 NA NA NA NA NA NA 12517.05 12653.21 1.011 26.0 26.0 NA NA NA NA 12653.21 12517.05 26.0 26.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0857142857142856 2.342857142857143 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 8 1, 3, 4 PLLPLLLLL LLPLLLLLL PickPocket 12653.21 4830.5 0.382 PickPocket 26.0 6.9 101 0.891 NA NA NA NA NA NA 12653.21 4830.5 0.382 26.0 6.9 NA NA NA NA 4830.5 12653.21 6.9 26.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 9 2, 3 LLPLLLLLG LPLLLLLLG PickPocket 12653.21 50000.0 3.952 PickPocket 26.0 73.0 101 0.891 NA NA NA NA NA NA 12653.21 50000.0 3.952 26.0 73.0 NA NA NA NA 50000.0 12653.21 73.0 26.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.4285714285714293 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 1 9 KSVNEALNN KSVNEALNH PickPocket 12930.01 15710.15 1.215 PickPocket 27.0 33.0 30 0.1 NA NA NA NA NA NA 12930.01 15710.15 1.215 27.0 33.0 NA NA NA NA 15710.15 12930.01 33.0 27.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6 -0.21428571428571427 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 8 2 VEMSHFEPN VAMSHFEPN PickPocket 13070.67 9865.62 0.755 PickPocket 27.0 20.0 113 0.044 NA NA NA NA NA NA 13070.67 9865.62 0.755 27.0 20.0 NA NA NA NA 9865.62 13070.67 20.0 27.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 19 NA AGCPWSGTG NA PickPocket 13501.89 NA NA PickPocket 28.0 NA 142 0.768 NA NA NA NA NA NA 13501.89 NA NA 28.0 NA NA NA NA NA NA 13501.89 NA 28.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.3285714285714286 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 2 8 AVRPLELVY AVRPLELAY PickPocket 14099.07 23444.56 1.663 PickPocket 29.0 46.0 113 0.053 NA NA NA NA NA NA 14099.07 23444.56 1.663 29.0 46.0 NA NA NA NA 23444.56 14099.07 46.0 29.0 6.USP18.ENST00000215794.7.missense.124A/V 0.1285714285714286 0.9142857142857144 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 7 3 GNLFNCECD GNPFNCECD PickPocket 14252.45 10874.65 0.763 PickPocket 29.0 23.0 303 0.135 NA NA NA NA NA NA 14252.45 10874.65 0.763 29.0 23.0 NA NA NA NA 10874.65 14252.45 23.0 29.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 2 8 SLFGALVRS SLFGALVHS PickPocket 14564.23 12382.34 0.85 PickPocket 30.0 26.0 210 0.686 NA NA NA NA NA NA 14564.23 12382.34 0.85 30.0 26.0 NA NA NA NA 12382.34 14564.23 26.0 30.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R 0.9857142857142857 2.1714285714285713 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 6 4 ALNNLLTEE ALNHLLTEE PickPocket 14722.66 15710.15 1.067 PickPocket 31.0 33.0 30 0.1 NA NA NA NA NA NA 14722.66 15710.15 1.067 31.0 33.0 NA NA NA NA 15710.15 14722.66 33.0 31.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.7857142857142856 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 6 4 VWTHSRDPE VWTRSRDPE PickPocket 15044.73 16228.45 1.079 PickPocket 31.0 34.0 56 0.071 NA NA NA NA NA NA 15044.73 16228.45 1.079 31.0 34.0 NA NA NA NA 16228.45 15044.73 34.0 31.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.5428571428571423 -1.3428571428571427 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 7 1, 2 TLLLAAAGG RTLLAAAGG PickPocket 16053.81 6128.72 0.382 PickPocket 33.0 9.7 76 0.158 NA NA NA NA NA NA 16053.81 6128.72 0.382 33.0 9.7 NA NA NA NA 6128.72 16053.81 9.7 33.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.742857142857143 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 2 8 YQQRPGSAP YQQRPGSSP PickPocket 16763.86 12249.09 0.731 PickPocket 34.0 25.0 7 0.571 NA NA NA NA NA NA 16763.86 12249.09 0.731 34.0 25.0 NA NA NA NA 12249.09 16763.86 25.0 34.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.5142857142857142 -1.5142857142857142 False False True 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 9 1 YLSDRCKIL CLSDRCKIL PickPocket 16763.86 21734.48 1.297 PickPocket 34.0 44.0 92 0.043 NA NA NA NA NA NA 16763.86 21734.48 1.297 34.0 44.0 NA NA NA NA 21734.48 16763.86 44.0 34.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857163 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 20 NA GCPWSGTGQ NA PickPocket 17130.58 NA NA PickPocket 35.0 NA 142 0.768 NA NA NA NA NA NA 17130.58 NA NA 35.0 NA NA NA NA NA NA 17130.58 NA 35.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.1857142857142857 -0.32857142857142857 False False False 1 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 4 6 VSPEPARPP VSPEPPRPP PickPocket 18082.85 17316.93 0.958 PickPocket 37.0 36.0 245 0.486 NA NA NA NA NA NA 18082.85 17316.93 0.958 37.0 36.0 NA NA NA NA 17316.93 18082.85 36.0 37.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.7999999999999996 -0.8571428571428571 False False True 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 5 5 ISCTGSSGS ISCTRSSGS PickPocket 18279.56 23192.26 1.269 PickPocket 37.0 46.0 5 1.0 NA NA NA NA NA NA 18279.56 23192.26 1.269 37.0 46.0 NA NA NA NA 23192.26 18279.56 46.0 37.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.20000000000000004 0.5 False False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 3 7 VTISCTGSS VTISCTRSS PickPocket 18478.42 18882.64 1.022 PickPocket 38.0 38.0 5 1.0 NA NA NA NA NA NA 18478.42 18882.64 1.022 38.0 38.0 NA NA NA NA 18882.64 18478.42 38.0 38.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 1 9 ALGWEFLAF ALGWEFLAS PickPocket 18882.64 36141.06 1.914 PickPocket 38.0 62.0 171 0.959 NA NA NA NA NA NA 18882.64 36141.06 1.914 38.0 62.0 NA NA NA NA 36141.06 18882.64 62.0 38.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.9142857142857143 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 6 4 FNPQTDYLT FNPETDYLT PickPocket 19295.7 17505.31 0.907 PickPocket 39.0 36.0 136 0.25 NA NA NA NA NA NA 19295.7 17505.31 0.907 39.0 36.0 NA NA NA NA 17505.31 19295.7 36.0 39.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.0714285714285716 -1.0714285714285716 False False False 0 False 1 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 6 4 SCTGSSGSI SCTRSSGSI PickPocket 19505.61 23192.26 1.189 PickPocket 40.0 46.0 5 1.0 NA NA NA NA NA NA 19505.61 23192.26 1.189 40.0 46.0 NA NA NA NA 23192.26 19505.61 46.0 40.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.08571428571428566 0.08571428571428566 False False False 1 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 1 9 VSLFGALVR VSLFGALVH PickPocket 19505.61 13501.89 0.692 PickPocket 40.0 28.0 210 0.686 NA NA NA NA NA NA 19505.61 13501.89 0.692 40.0 28.0 NA NA NA NA 13501.89 19505.61 28.0 40.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R 1.6428571428571428 2.1714285714285713 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 3 7 QQRPGSAPT QQRPGSSPT PickPocket 19717.81 19932.31 1.011 PickPocket 40.0 40.0 7 0.571 NA NA NA NA NA NA 19717.81 19932.31 1.011 40.0 40.0 NA NA NA NA 19932.31 19717.81 40.0 40.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.1142857142857143 -1.1142857142857143 True False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 2 8 VCELAGNLF VCELAGNPF PickPocket 19717.81 17316.93 0.878 PickPocket 40.0 36.0 303 0.135 NA NA NA NA NA NA 19717.81 17316.93 0.878 40.0 36.0 NA NA NA NA 17316.93 19717.81 36.0 40.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 0.7000000000000001 False False False 1 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 9 1 TQEVKVKEP PQEVKVKEP PickPocket 20149.14 50000.0 2.481 PickPocket 41.0 73.0 185 0.038 NA NA NA NA NA NA 20149.14 50000.0 2.481 41.0 73.0 NA NA NA NA 50000.0 20149.14 73.0 41.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.1428571428571428 -1.0142857142857142 False False True 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 9 1 NLLTEEEDY HLLTEEEDY PickPocket 20368.33 10527.33 0.517 PickPocket 41.0 22.0 30 0.1 NA NA NA NA NA NA 20368.33 10527.33 0.517 41.0 22.0 NA NA NA NA 10527.33 20368.33 22.0 41.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.742857142857143 -1.0142857142857145 False False False 0 True 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 3 7 CELAGNLFN CELAGNPFN PickPocket 20813.9 17316.93 0.832 PickPocket 42.0 36.0 303 0.135 NA NA NA NA NA NA 20813.9 17316.93 0.832 42.0 36.0 NA NA NA NA 17316.93 20813.9 36.0 42.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 0.6857142857142856 True False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 11 NA TGQGSGEKA NA PickPocket 21040.32 NA NA PickPocket 42.0 NA 142 0.768 NA NA NA NA NA NA 21040.32 NA NA 42.0 NA NA NA NA NA NA 21040.32 NA 42.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.5285714285714287 -1.3857142857142857 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 9 1 FTRLTSELN STRLTSELN PickPocket 21040.32 17316.93 0.823 PickPocket 42.0 36.0 171 0.959 NA NA NA NA NA NA 21040.32 17316.93 0.823 42.0 36.0 NA NA NA NA 17316.93 21040.32 36.0 42.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.7714285714285715 -0.3714285714285715 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 6 NA RSAGSTGQG NA PickPocket 21734.48 NA NA PickPocket 44.0 NA 142 0.768 NA NA NA NA NA NA 21734.48 NA NA 44.0 NA NA NA NA NA NA 21734.48 NA 44.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6285714285714287 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 9 1 ARPPQQPVP PRPPQQPVP PickPocket 22209.93 50000.0 2.251 PickPocket 44.0 73.0 245 0.486 NA NA NA NA NA NA 22209.93 50000.0 2.251 44.0 73.0 NA NA NA NA 50000.0 22209.93 73.0 44.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 1 9 VLCQRAKVE VLCQRAKVA PickPocket 22209.93 19088.05 0.859 PickPocket 44.0 39.0 113 0.044 NA NA NA NA NA NA 22209.93 19088.05 0.859 44.0 39.0 NA NA NA NA 19088.05 22209.93 39.0 44.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.9857142857142857 0.0571428571428572 False False False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 4 6 WEFLAFTRL WEFLASTRL PickPocket 22209.93 25017.04 1.126 PickPocket 44.0 49.0 171 0.959 NA NA NA NA NA NA 22209.93 25017.04 1.126 44.0 49.0 NA NA NA NA 25017.04 22209.93 49.0 44.0 22.PANX2.ENST00000395842.2.missense.147S/F 1.4000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 6 4 DMDYLSDRC DMDCLSDRC PickPocket 22451.54 23957.42 1.067 PickPocket 45.0 47.0 92 0.043 NA NA NA NA NA NA 22451.54 23957.42 1.067 45.0 47.0 NA NA NA NA 23957.42 22451.54 47.0 45.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.042857142857143 -0.9857142857142857 False True False 1 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 8 2 NQDAAQGIA NEDAAQGIA PickPocket 22695.78 50000.0 2.203 PickPocket 45.0 73.0 22 0.5 NA NA NA NA NA NA 22695.78 50000.0 2.203 45.0 73.0 NA NA NA NA 50000.0 22695.78 73.0 45.0 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.35714285714285715 0.35714285714285715 False False False 0 True 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 6 4 IGKHGGVSL IGKPGGVSL PickPocket 22695.78 19295.7 0.85 PickPocket 45.0 39.0 140 0.179 NA NA NA NA NA NA 22695.78 19295.7 0.85 45.0 39.0 NA NA NA NA 19295.7 22695.78 39.0 45.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.10000000000000002 0.05714285714285713 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 7 3 GKHGGVSLS GKPGGVSLS PickPocket 22695.78 38984.65 1.718 PickPocket 45.0 65.0 140 0.179 NA NA NA NA NA NA 22695.78 38984.65 1.718 45.0 65.0 NA NA NA NA 38984.65 22695.78 65.0 45.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.3428571428571429 0.3428571428571429 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 2 8 QPCDDMDYL QPCDDMDCL PickPocket 22695.78 27875.69 1.228 PickPocket 45.0 53.0 92 0.043 NA NA NA NA NA NA 22695.78 27875.69 1.228 45.0 53.0 NA NA NA NA 27875.69 22695.78 53.0 45.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.5142857142857142 -0.5142857142857142 True False False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 3 7 TLKFNPQTD TLKFNPETD PickPocket 22695.78 24218.04 1.067 PickPocket 45.0 47.0 136 0.25 NA NA NA NA NA NA 22695.78 24218.04 1.067 45.0 47.0 NA NA NA NA 24218.04 22695.78 47.0 45.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.9857142857142855 -0.942857142857143 False False False 0 False 1 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 1 9 KAVRPLELV KAVRPLELA PickPocket 23192.26 30396.07 1.311 PickPocket 46.0 56.0 113 0.053 NA NA NA NA NA NA 23192.26 30396.07 1.311 46.0 56.0 NA NA NA NA 30396.07 23192.26 56.0 46.0 6.USP18.ENST00000215794.7.missense.124A/V 0.9142857142857144 0.9142857142857144 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 6 4 ALVRSRTYD ALVHSRTYD PickPocket 23192.26 21500.59 0.927 PickPocket 46.0 43.0 210 0.686 NA NA NA NA NA NA 23192.26 21500.59 0.927 46.0 43.0 NA NA NA NA 21500.59 23192.26 43.0 46.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.5857142857142856 -0.09999999999999987 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 4 6 YGLLHIYGS YGLLHTYGS PickPocket 24747.82 18679.43 0.755 PickPocket 48.0 38.0 120 0.233 NA NA NA NA NA NA 24747.82 18679.43 0.755 48.0 38.0 NA NA NA NA 18679.43 24747.82 38.0 48.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.914285714285714 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 9 1 HSRDPEGSS RSRDPEGSS PickPocket 25017.04 15044.73 0.601 PickPocket 49.0 31.0 56 0.071 NA NA NA NA NA NA 25017.04 15044.73 0.601 49.0 31.0 NA NA NA NA 15044.73 25017.04 31.0 49.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 4 6 QRPGSAPTT QRPGSSPTT PickPocket 25017.04 23192.26 0.927 PickPocket 49.0 46.0 7 0.571 NA NA NA NA NA NA 25017.04 23192.26 0.927 49.0 46.0 NA NA NA NA 23192.26 25017.04 46.0 49.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5714285714285714 -0.5714285714285714 True False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 7 3 LNNLLTEEE LNHLLTEEE PickPocket 25289.19 6903.33 0.273 PickPocket 49.0 13.0 30 0.1 NA NA NA NA NA NA 25289.19 6903.33 0.273 49.0 13.0 NA NA NA NA 6903.33 25289.19 13.0 49.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.02857142857142847 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 5 5 RPGSAPTTV RPGSSPTTV PickPocket 25289.19 26407.71 1.044 PickPocket 49.0 51.0 7 0.571 NA NA NA NA NA NA 25289.19 26407.71 1.044 49.0 51.0 NA NA NA NA 26407.71 25289.19 51.0 49.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.2571428571428571 0.2571428571428571 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 15 NA SGEKAGCPW NA PickPocket 25289.19 NA NA PickPocket 49.0 NA 142 0.768 NA NA NA NA NA NA 25289.19 NA NA 49.0 NA NA NA NA NA NA 25289.19 NA 49.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8571428571428574 -0.6714285714285715 False False False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 5 5 RAKVEMSHF RAKVAMSHF PickPocket 25289.19 21970.92 0.869 PickPocket 49.0 44.0 113 0.044 NA NA NA NA NA NA 25289.19 21970.92 0.869 49.0 44.0 NA NA NA NA 21970.92 25289.19 44.0 49.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.35714285714285715 -0.35714285714285715 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 18 NA KAGCPWSGT NA PickPocket 25564.3 NA NA PickPocket 50.0 NA 142 0.768 NA NA NA NA NA NA 25564.3 NA NA 50.0 NA NA NA NA NA NA 25564.3 NA 50.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.32857142857142857 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 7 3 LHIYGSGGY LHTYGSGGY PickPocket 25564.3 29108.61 1.139 PickPocket 50.0 54.0 120 0.233 NA NA NA NA NA NA 25564.3 29108.61 1.139 50.0 54.0 NA NA NA NA 29108.61 25564.3 54.0 50.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.014285714285714266 0.3142857142857142 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 3 7 LFGALVRSR LFGALVHSR PickPocket 25842.4 25017.04 0.968 PickPocket 50.0 49.0 210 0.686 NA NA NA NA NA NA 25842.4 25017.04 0.968 50.0 49.0 NA NA NA NA 25017.04 25842.4 49.0 50.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.05714285714285732 1.6428571428571428 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 8 2 KHGGVSLSK KPGGVSLSK PickPocket 26985.39 50000.0 1.853 PickPocket 51.0 73.0 140 0.179 NA NA NA NA NA NA 26985.39 50000.0 1.853 51.0 73.0 NA NA NA NA 50000.0 26985.39 73.0 51.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.24285714285714294 0.3428571428571429 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 3 7 CQRAKVEMS CQRAKVAMS PickPocket 26985.39 26407.71 0.979 PickPocket 51.0 51.0 113 0.044 NA NA NA NA NA NA 26985.39 26407.71 0.979 51.0 51.0 NA NA NA NA 26407.71 26985.39 51.0 51.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.6857142857142857 -0.6857142857142857 True False False 1 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 7 5, 9 LPLLPLLLL LPLLLLLLG PickPocket 27278.95 50000.0 1.833 PickPocket 52.0 73.0 101 0.891 NA NA NA NA NA NA 27278.95 50000.0 1.833 52.0 73.0 NA NA NA NA 50000.0 27278.95 73.0 52.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 1 9 HHEDLIGKH HHEDLIGKP PickPocket 27278.95 27575.71 1.011 PickPocket 52.0 52.0 140 0.179 NA NA NA NA NA NA 27278.95 27575.71 1.011 52.0 52.0 NA NA NA NA 27575.71 27278.95 52.0 52.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.8857142857142858 -0.7857142857142859 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 10 NA STGQGSGEK NA PickPocket 27875.69 NA NA PickPocket 53.0 NA 142 0.768 NA NA NA NA NA NA 27875.69 NA NA 53.0 NA NA NA NA NA NA 27875.69 NA 53.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.842857142857143 -1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 6 4 ASGYESRVE ASGSESRVE PickPocket 27875.69 30726.73 1.102 PickPocket 53.0 56.0 116 0.043 NA NA NA NA NA NA 27875.69 30726.73 1.102 53.0 56.0 NA NA NA NA 30726.73 27875.69 56.0 53.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.4000000000000001 -1.0142857142857145 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 4 7 LSRTLLLAA LSRTLLAAA PickPocket 28178.94 27875.69 0.989 PickPocket 53.0 53.0 76 0.158 NA NA NA NA NA NA 28178.94 27875.69 0.989 53.0 53.0 NA NA NA NA 27875.69 28178.94 53.0 53.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.4 1.4 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 6 4 AGNLFNCEC AGNPFNCEC PickPocket 28178.94 20589.91 0.731 PickPocket 53.0 42.0 303 0.135 NA NA NA NA NA NA 28178.94 20589.91 0.731 53.0 42.0 NA NA NA NA 20589.91 28178.94 42.0 53.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.5 False True False 2 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 8 2 TTQKRNSRR TAQKRNSRR PickPocket 28795.36 50000.0 1.736 PickPocket 54.0 73.0 96 0.042 NA NA NA NA NA NA 28795.36 50000.0 1.736 54.0 73.0 NA NA NA NA 50000.0 28795.36 73.0 54.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6 -2.5142857142857147 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 5 5 SPEPARPPQ SPEPPRPPQ PickPocket 29108.61 33869.37 1.164 PickPocket 54.0 60.0 245 0.486 NA NA NA NA NA NA 29108.61 33869.37 1.164 54.0 60.0 NA NA NA NA 33869.37 29108.61 60.0 54.0 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -1.6857142857142855 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 9 1 EMSHFEPNE AMSHFEPNE PickPocket 29108.61 13070.67 0.449 PickPocket 54.0 27.0 113 0.044 NA NA NA NA NA NA 29108.61 13070.67 0.449 54.0 27.0 NA NA NA NA 13070.67 29108.61 27.0 54.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.9000000000000001 -1.1285714285714286 True False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 3 7 VRPLELVYC VRPLELAYC PickPocket 30396.07 28178.94 0.927 PickPocket 56.0 53.0 113 0.053 NA NA NA NA NA NA 30396.07 28178.94 0.927 56.0 53.0 NA NA NA NA 28178.94 30396.07 53.0 56.0 6.USP18.ENST00000215794.7.missense.124A/V 1.1285714285714286 1.1285714285714286 False True False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 7 3 NPQTDYLTG NPETDYLTG PickPocket 30726.73 50000.0 1.627 PickPocket 56.0 73.0 136 0.25 NA NA NA NA NA NA 30726.73 50000.0 1.627 56.0 73.0 NA NA NA NA 50000.0 30726.73 73.0 56.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9000000000000001 -0.9000000000000001 False False False 0 True 1 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 4 6 DLIGKHGGV DLIGKPGGV PickPocket 31740.46 32434.8 1.022 PickPocket 57.0 58.0 140 0.179 NA NA NA NA NA NA 31740.46 32434.8 1.022 57.0 58.0 NA NA NA NA 32434.8 31740.46 58.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.05714285714285713 0.05714285714285713 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 3 7 TTVVVTTQK TTVVVTAQK PickPocket 31740.46 30396.07 0.958 PickPocket 57.0 56.0 96 0.042 NA NA NA NA NA NA 31740.46 30396.07 0.958 57.0 56.0 NA NA NA NA 30396.07 31740.46 56.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 0.5428571428571433 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 5 5 GALVRSRTY GALVHSRTY PickPocket 32085.75 23444.56 0.731 PickPocket 58.0 46.0 210 0.686 NA NA NA NA NA NA 32085.75 23444.56 0.731 58.0 46.0 NA NA NA NA 23444.56 32085.75 46.0 58.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.5428571428571428 -0.05714285714285732 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 3 7 VQGIANQDA VQGIANEDA PickPocket 32434.8 34610.27 1.067 PickPocket 58.0 61.0 22 0.5 NA NA NA NA NA NA 32434.8 34610.27 1.067 58.0 61.0 NA NA NA NA 34610.27 32434.8 61.0 58.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 -0.0571428571428572 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 9 NA GSTGQGSGE NA PickPocket 32434.8 NA NA PickPocket 58.0 NA 142 0.768 NA NA NA NA NA NA 32434.8 NA NA 58.0 NA NA NA NA NA NA 32434.8 NA 58.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.3857142857142857 -1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 7 3 CTGSSGSIA CTRSSGSIA PickPocket 33144.32 21500.59 0.649 PickPocket 59.0 43.0 5 1.0 NA NA NA NA NA NA 33144.32 21500.59 0.649 59.0 43.0 NA NA NA NA 21500.59 33144.32 43.0 59.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.4428571428571428 0.4428571428571428 True False False 1 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 8 2 NNLLTEEED NHLLTEEED PickPocket 34237.82 35367.39 1.033 PickPocket 60.0 62.0 30 0.1 NA NA NA NA NA NA 34237.82 35367.39 1.033 60.0 62.0 NA NA NA NA 35367.39 34237.82 62.0 60.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 -1.0142857142857145 False False False 0 True 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 5 5 LIGKHGGVS LIGKPGGVS PickPocket 34237.82 45854.11 1.339 PickPocket 60.0 70.0 140 0.179 NA NA NA NA NA NA 34237.82 45854.11 1.339 60.0 70.0 NA NA NA NA 45854.11 34237.82 70.0 60.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.7000000000000001 0.05714285714285713 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 6 4 FLAFTRLTS FLASTRLTS PickPocket 34610.27 40270.83 1.164 PickPocket 61.0 66.0 171 0.959 NA NA NA NA NA NA 34610.27 40270.83 1.164 61.0 66.0 NA NA NA NA 40270.83 34610.27 66.0 61.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.24285714285714272 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 7 3 LAFTRLTSE LASTRLTSE PickPocket 34610.27 50000.0 1.445 PickPocket 61.0 73.0 171 0.959 NA NA NA NA NA NA 34610.27 50000.0 1.445 61.0 73.0 NA NA NA NA 50000.0 34610.27 73.0 61.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.5142857142857143 0.8999999999999997 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 2 8 TVTISCTGS TVTISCTRS PickPocket 35752.13 50000.0 1.399 PickPocket 62.0 73.0 5 1.0 NA NA NA NA NA NA 35752.13 50000.0 1.399 62.0 73.0 NA NA NA NA 50000.0 35752.13 73.0 62.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5142857142857142 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 4 6 SHVWTHSRD SHVWTRSRD PickPocket 36931.66 43911.91 1.189 PickPocket 63.0 69.0 56 0.071 NA NA NA NA NA NA 36931.66 43911.91 1.189 63.0 69.0 NA NA NA NA 43911.91 36931.66 69.0 63.0 5.CECR2.ENST00000262608.8.missense.535R/H -1.3428571428571427 -0.7714285714285714 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 10 1, 2 LPLLLLLGA PLLLLLLGA PickPocket 37333.42 30396.07 0.814 PickPocket 64.0 56.0 101 0.891 NA NA NA NA NA NA 37333.42 30396.07 0.814 64.0 56.0 NA NA NA NA 30396.07 37333.42 56.0 64.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.9142857142857146 3.028571428571429 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 3 8 TLSRTLLLA TLSRTLLAA PickPocket 37739.56 48929.64 1.297 PickPocket 64.0 73.0 76 0.158 NA NA NA NA NA NA 37739.56 48929.64 1.297 64.0 73.0 NA NA NA NA 48929.64 37739.56 73.0 64.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0285714285714285 1.3142857142857143 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 1 9 LHTVSPEPA LHTVSPEPP PickPocket 37739.56 50000.0 1.325 PickPocket 64.0 73.0 245 0.486 NA NA NA NA NA NA 37739.56 50000.0 1.325 64.0 73.0 NA NA NA NA 50000.0 37739.56 73.0 64.0 15.GGA1.ENST00000343632.4.missense.484P/A -0.31428571428571433 -0.2571428571428572 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 4 7, 8, 9 GGRSAGSTG GGRSAGQHW PickPocket 38150.11 49461.93 1.297 PickPocket 64.0 73.0 142 0.768 NA NA NA NA NA NA 38150.11 49461.93 1.297 64.0 73.0 NA NA NA NA 49461.93 38150.11 73.0 64.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7857142857142857 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 5 5 DDMDYLSDR DDMDCLSDR PickPocket 38565.12 50000.0 1.297 PickPocket 65.0 73.0 92 0.043 NA NA NA NA NA NA 38565.12 50000.0 1.297 65.0 73.0 NA NA NA NA 50000.0 38565.12 73.0 65.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.1285714285714286 -0.9857142857142857 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 5 5 PLELVYCLQ PLELAYCLQ PickPocket 39408.75 45360.65 1.151 PickPocket 65.0 70.0 113 0.053 NA NA NA NA NA NA 39408.75 45360.65 1.151 65.0 70.0 NA NA NA NA 45360.65 39408.75 70.0 65.0 6.USP18.ENST00000215794.7.missense.124A/V 0.8571428571428571 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 4 6 TISCTGSSG TISCTRSSG PickPocket 39837.46 43911.91 1.102 PickPocket 66.0 69.0 5 1.0 NA NA NA NA NA NA 39837.46 43911.91 1.102 66.0 69.0 NA NA NA NA 43911.91 39837.46 69.0 66.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.19999999999999998 0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 2 8 HEDLIGKHG HEDLIGKPG PickPocket 39837.46 30396.07 0.763 PickPocket 66.0 56.0 140 0.179 NA NA NA NA NA NA 39837.46 30396.07 0.763 66.0 56.0 NA NA NA NA 30396.07 39837.46 56.0 66.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.44285714285714295 -0.44285714285714295 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 6 4 VVTTQKRNS VVTAQKRNS PickPocket 40708.92 36141.06 0.888 PickPocket 66.0 62.0 96 0.042 NA NA NA NA NA NA 40708.92 36141.06 0.888 66.0 62.0 NA NA NA NA 36141.06 40708.92 62.0 66.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -2.5142857142857147 -0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 5 5 VVVTTQKRN VVVTAQKRN PickPocket 41151.77 42971.89 1.044 PickPocket 67.0 68.0 96 0.042 NA NA NA NA NA NA 41151.77 42971.89 1.044 67.0 68.0 NA NA NA NA 42971.89 41151.77 68.0 67.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -1.8 0.5428571428571433 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 5 5 EALNNLLTE EALNHLLTE PickPocket 41599.44 40708.92 0.979 PickPocket 67.0 66.0 30 0.1 NA NA NA NA NA NA 41599.44 40708.92 0.979 67.0 66.0 NA NA NA NA 40708.92 41599.44 66.0 67.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.02857142857142847 0.7857142857142856 True False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 9 1 HGGVSLSKI PGGVSLSKI PickPocket 41599.44 50000.0 1.202 PickPocket 67.0 73.0 140 0.179 NA NA NA NA NA NA 41599.44 50000.0 1.202 67.0 73.0 NA NA NA NA 50000.0 41599.44 73.0 67.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.9428571428571428 0.9428571428571428 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 5 5 LAGNLFNCE LAGNPFNCE PickPocket 41599.44 50000.0 1.202 PickPocket 67.0 73.0 303 0.135 NA NA NA NA NA NA 41599.44 50000.0 1.202 67.0 73.0 NA NA NA NA 50000.0 41599.44 73.0 67.0 13.ELFN2.ENST00000402918.2.missense.186P/L -0.2571428571428572 0.6857142857142856 False False False 1 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 2 8 HTVSPEPAR HTVSPEPPR PickPocket 41599.44 28178.94 0.677 PickPocket 67.0 53.0 245 0.486 NA NA NA NA NA NA 41599.44 28178.94 0.677 67.0 53.0 NA NA NA NA 28178.94 41599.44 53.0 67.0 15.GGA1.ENST00000343632.4.missense.484P/A -0.8571428571428571 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 6 4 LELVYCLQK LELAYCLQK PickPocket 42051.98 35752.13 0.85 PickPocket 67.0 62.0 113 0.053 NA NA NA NA NA NA 42051.98 35752.13 0.85 67.0 62.0 NA NA NA NA 35752.13 42051.98 62.0 67.0 6.USP18.ENST00000215794.7.missense.124A/V 0.7999999999999999 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 21 NA CPWSGTGQH NA PickPocket 42509.45 NA NA PickPocket 68.0 NA 142 0.768 NA NA NA NA NA NA 42509.45 NA NA 68.0 NA NA NA NA NA NA 42509.45 NA 68.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.4142857142857141 -0.3285714285714286 True False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 4 6 CDDMDYLSD CDDMDCLSD PickPocket 44389.61 50000.0 1.126 PickPocket 69.0 73.0 92 0.043 NA NA NA NA NA NA 44389.61 50000.0 1.126 69.0 73.0 NA NA NA NA 50000.0 44389.61 73.0 69.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142857 -0.5142857142857142 True False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 7 NA SAGSTGQGS NA PickPocket 45360.65 NA NA PickPocket 70.0 NA 142 0.768 NA NA NA NA NA NA 45360.65 NA NA 70.0 NA NA NA NA NA NA 45360.65 NA 70.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 1 9 SGGSHVWTH SGGSHVWTR PickPocket 46352.93 50000.0 1.079 PickPocket 71.0 73.0 56 0.071 NA NA NA NA NA NA 46352.93 50000.0 1.079 71.0 73.0 NA NA NA NA 50000.0 46352.93 73.0 71.0 5.CECR2.ENST00000262608.8.missense.535R/H -0.7142857142857143 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 7 3 GSAPTTVIY GSSPTTVIY PickPocket 46352.93 40270.83 0.869 PickPocket 71.0 66.0 7 0.571 NA NA NA NA NA NA 46352.93 40270.83 0.869 71.0 66.0 NA NA NA NA 40270.83 46352.93 66.0 71.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.8857142857142858 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 1 9 AGTLKFNPQ AGTLKFNPE PickPocket 46857.18 43439.36 0.927 PickPocket 71.0 69.0 136 0.25 NA NA NA NA NA NA 46857.18 43439.36 0.927 71.0 69.0 NA NA NA NA 43439.36 46857.18 69.0 71.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 -0.0142857142857143 False False False 0 False 1 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 8 2 PQTDYLTGT PETDYLTGT PickPocket 46857.18 50000.0 1.067 PickPocket 71.0 73.0 136 0.25 NA NA NA NA NA NA 46857.18 50000.0 1.067 71.0 73.0 NA NA NA NA 50000.0 46857.18 73.0 71.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.5 -0.5 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 14 NA GSGEKAGCP NA PickPocket 47882.2 NA NA PickPocket 72.0 NA 142 0.768 NA NA NA NA NA NA 47882.2 NA NA 72.0 NA NA NA NA NA NA 47882.2 NA 72.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.6714285714285715 False False True 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 6 4 AKVEMSHFE AKVAMSHFE PickPocket 48403.09 44872.5 0.927 PickPocket 72.0 70.0 113 0.044 NA NA NA NA NA NA 48403.09 44872.5 0.927 72.0 70.0 NA NA NA NA 44872.5 48403.09 70.0 72.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.3000000000000001 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 3 9 PPPLLPLLP PPPLLPLLL PickPocket 50000.0 43911.91 0.878 PickPocket 73.0 69.0 101 0.891 NA NA NA NA NA NA 50000.0 43911.91 0.878 73.0 69.0 NA NA NA NA 43911.91 50000.0 69.0 73.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.4857142857142858 1.4857142857142858 False False True 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 4 8 PPLLPLLPL PPLLPLLLL PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 11 1 PLLLLLGAS LLLLLLGAS PickPocket 50000.0 21970.92 0.439 PickPocket 73.0 44.0 101 0.891 NA NA NA NA NA NA 50000.0 21970.92 0.439 73.0 44.0 NA NA NA NA 21970.92 50000.0 44.0 73.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.2571428571428567 2.9142857142857146 False False False 0 False 0 NA NA NA NA -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-G*01:09 9 2 9 SAAAAAAAV SAAAAAAAA PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 128 0.977 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.142857142857143 2.142857142857143 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 5 6, 9 SRTLLLAAA SRTLLAAAG PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.3000000000000003 2.3000000000000003 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 2 8 GGSHVWTHS GGSHVWTRS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 5.CECR2.ENST00000262608.8.missense.535R/H -0.7714285714285714 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 8 2 THSRDPEGS TRSRDPEGS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 7 3 ELVYCLQKC ELAYCLQKC PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 6.USP18.ENST00000215794.7.missense.124A/V 0.6142857142857141 0.8571428571428571 True True False 2 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 4 6 NEALNNLLT NEALNHLLT PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.7857142857142856 0.7857142857142856 False False False 0 True 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 1 9 DAVQGIANQ DAVQGIANE PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.0571428571428572 0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 4 6 QGIANQDAA QGIANEDAA PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.08571428571428576 -0.08571428571428576 True False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 5 5 GIANQDAAQ GIANEDAAQ PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.2285714285714284 -0.08571428571428576 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 6 4 IANQDAAQG IANEDAAQG PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.5428571428571427 -0.08571428571428576 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 9 1 QDAAQGIAK EDAAQGIAK PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.3 0.35714285714285715 True False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 8 2 TGSSGSIAS TRSSGSIAS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.38571428571428573 0.4428571428571428 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 9 1 GSSGSIASN RSSGSIASN PickPocket 50000.0 19505.61 0.39 PickPocket 73.0 40.0 5 1.0 NA NA NA NA NA NA 50000.0 19505.61 0.39 73.0 40.0 NA NA NA NA 19505.61 50000.0 40.0 73.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.0 0.4428571428571428 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 6 4 PGSAPTTVI PGSSPTTVI PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.9571428571428572 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 9 1 APTTVIYED SPTTVIYED PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.14285714285714274 0.8857142857142858 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 3 7 EDLIGKHGG EDLIGKPGG PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 11.TPST2.ENST00000338754.4.missense.274P/H -3.172065784643304e-17 -3.172065784643304e-17 True False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 1 9 SPVKEEEKT SPVKEEEKP PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -1.8 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 2 8 PVKEEEKTQ PVKEEEKPQ PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T -3.2142857142857144 -2.1142857142857143 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 3 7 VKEEEKTQE VKEEEKPQE PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T -3.1571428571428575 -2.1142857142857143 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 5 5 EEEKTQEVK EEEKPQEVK PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -2.0571428571428574 True False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 6 4 EEKTQEVKV EEKPQEVKV PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.014285714285714 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 7 3 EKTQEVKVK EKPQEVKVK PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.0142857142857142 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 4 6 ELAGNLFNC ELAGNPFNC PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.5 0.6857142857142856 True True False 1 False 0 NA NA NA NA -22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-G*01:09 9 9 9 NMSSFKLKQ NMSSFKLKE PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 117 0.496 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 14.LGALS2.ENST00000215886.4.missense.132E/Q -0.9000000000000001 -0.07142857142857155 False False False 0 True 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 3 7 TVSPEPARP TVSPEPPRP PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.6857142857142855 -0.31428571428571433 False False True 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 6 4 PEPARPPQQ PEPPRPPQQ PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -1.7999999999999996 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 7 3 EPARPPQQP EPPRPPQQP PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -2.0714285714285716 True False True 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 8 2 PARPPQQPV PPRPPQQPV PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.7285714285714289 -1.7285714285714289 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 2 9 GGGGRSAGS GGGGRSAGQ PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.7285714285714285 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 3 8, 9 GGGRSAGST GGGRSAGQH PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7285714285714286 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 5 6, 7, 8, 9 GRSAGSTGQ GRSAGQHWA PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6857142857142857 -0.6857142857142857 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 8 NA AGSTGQGSG NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 12 NA GQGSGEKAG NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0857142857142859 -1.0857142857142859 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 13 NA QGSGEKAGC NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6714285714285715 -0.6714285714285715 True True False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 16 NA GEKAGCPWS NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 17 NA EKAGCPWSG NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G 0.02857142857142855 0.02857142857142855 True False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 3 7 PCDDMDYLS PCDDMDCLS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142858 -0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 4 6 QRAKVEMSH QRAKVAMSH PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 113 0.044 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.5 -0.5 True False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 4 6 LKFNPQTDY LKFNPETDY PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.6142857142857143 -0.942857142857143 False False False 0 False 1 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 1 9 AKTTVVVTT AKTTVVVTA PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.4000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 4 6 TVVVTTQKR TVVVTAQKR PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -0.7000000000000001 1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 7 3 VTTQKRNSR VTAQKRNSR PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.0571428571428574 -1.8 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 9 1 TQKRNSRRQ AQKRNSRRQ PickPocket 50000.0 48403.09 0.968 PickPocket 73.0 72.0 96 0.042 NA NA NA NA NA NA 50000.0 48403.09 0.968 73.0 72.0 NA NA NA NA 48403.09 50000.0 72.0 73.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6000000000000005 -3.0571428571428574 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 4 6 FGALVRSRT FGALVHSRT PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.09999999999999987 0.9857142857142857 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 8 2 VRSRTYDMD VHSRTYDMD PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.7714285714285716 -1.5857142857142856 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 1 9 EERTEASGY EERTEASGS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.342857142857143 -1.342857142857143 True False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 2 8 ERTEASGYE ERTEASGSE PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2 -1.2 True False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 4 6 TEASGYESR TEASGSESR PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.3571428571428572 -1.2 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 5 5 EASGYESRV EASGSESRV PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.0142857142857145 -1.0142857142857145 True False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 9 1 YESRVEPPH SESRVEPPH PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285714 -1.5714285714285712 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 1 10 LYYSYGLLHI LYYSYGLLHT PickPocket 1469.28 2365.16 1.61 PickPocket 0.3 0.4 120 0.233 NA NA NA NA NA NA 1469.28 2365.16 1.61 0.3 0.4 NA NA NA NA 2365.16 1469.28 0.4 0.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9142857142857143 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 1 10 MYQPCDDMDY MYQPCDDMDC PickPocket 2904.96 2873.7 0.989 PickPocket 0.5 0.5 92 0.043 NA NA NA NA NA NA 2904.96 2873.7 0.989 0.5 0.5 NA NA NA NA 2873.7 2904.96 0.5 0.5 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 9 2 HIYGSGGYAL HTYGSGGYAL PickPocket 3766.31 3567.97 0.947 PickPocket 0.8 0.7 120 0.233 NA NA NA NA NA NA 3766.31 3567.97 0.947 0.8 0.7 NA NA NA NA 3567.97 3766.31 0.7 0.8 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.32857142857142857 0.32857142857142857 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 1 10 QWYQQRPGSA QWYQQRPGSS PickPocket 5267.25 6755.55 1.283 PickPocket 1.6 2.5 7 0.571 NA NA NA NA NA NA 5267.25 6755.55 1.283 1.6 2.5 NA NA NA NA 6755.55 5267.25 2.5 1.6 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.7857142857142858 -1.7857142857142858 True False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 9 2 LVYCLQKCNV LAYCLQKCNV PickPocket 5997.52 12382.34 2.065 PickPocket 2.1 7.4 113 0.053 NA NA NA NA NA NA 5997.52 12382.34 2.065 2.1 7.4 NA NA NA NA 12382.34 5997.52 7.4 2.1 6.USP18.ENST00000215794.7.missense.124A/V 0.3 0.7999999999999999 False False False 2 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 3 8 YSYGLLHIYG YSYGLLHTYG PickPocket 6399.79 6195.39 0.968 PickPocket 2.3 2.2 120 0.233 NA NA NA NA NA NA 6399.79 6195.39 0.968 2.3 2.2 NA NA NA NA 6195.39 6399.79 2.2 2.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9714285714285714 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 2 9 YQPCDDMDYL YQPCDDMDCL PickPocket 6610.93 7860.43 1.189 PickPocket 2.4 3.5 92 0.043 NA NA NA NA NA NA 6610.93 7860.43 1.189 2.4 3.5 NA NA NA NA 7860.43 6610.93 3.5 2.4 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.5142857142857142 -0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 4 7 GWEFLAFTRL GWEFLASTRL PickPocket 7054.34 6978.43 0.989 PickPocket 2.8 2.7 171 0.959 NA NA NA NA NA NA 7054.34 6978.43 0.989 2.8 2.7 NA NA NA NA 6978.43 7054.34 2.7 2.8 22.PANX2.ENST00000395842.2.missense.147S/F 1.4000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 1 10 LLHTVSPEPA LLHTVSPEPP PickPocket 9654.43 13797.25 1.429 PickPocket 5.0 8.8 245 0.486 NA NA NA NA NA NA 9654.43 13797.25 1.429 5.0 8.8 NA NA NA NA 13797.25 9654.43 8.8 5.0 15.GGA1.ENST00000343632.4.missense.484P/A -0.31428571428571433 0.7857142857142857 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 7 4 LLHIYGSGGY LLHTYGSGGY PickPocket 9972.95 8853.9 0.888 PickPocket 5.3 4.4 120 0.233 NA NA NA NA NA NA 9972.95 8853.9 0.888 5.3 4.4 NA NA NA NA 8853.9 9972.95 4.4 5.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.014285714285714266 0.914285714285714 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 3 8 AVQGIANQDA AVQGIANEDA PickPocket 11355.63 11355.63 1.0 PickPocket 6.4 6.4 22 0.5 NA NA NA NA NA NA 11355.63 11355.63 1.0 6.4 6.4 NA NA NA NA 11355.63 11355.63 6.4 6.4 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 9 2 KTQEVKVKEP KPQEVKVKEP PickPocket 11604.04 40708.92 3.508 PickPocket 6.6 35.0 185 0.038 NA NA NA NA NA NA 11604.04 40708.92 3.508 6.6 35.0 NA NA NA NA 40708.92 11604.04 35.0 6.6 12.NEFH.ENST00000310624.6.missense.830P/T -1.1428571428571428 -1.014285714285714 False False True 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 9 2 GYESRVEPPH GSESRVEPPH PickPocket 11604.04 45854.11 3.952 PickPocket 6.6 40.0 116 0.043 NA NA NA NA NA NA 11604.04 45854.11 3.952 6.6 40.0 NA NA NA NA 45854.11 11604.04 40.0 6.6 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285714 -1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 2 9 KSVNEALNNL KSVNEALNHL PickPocket 11730.27 16946.23 1.445 PickPocket 6.7 13.0 30 0.1 NA NA NA NA NA NA 11730.27 16946.23 1.445 6.7 13.0 NA NA NA NA 16946.23 11730.27 13.0 6.7 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 9 2 DYLSDRCKIL DCLSDRCKIL PickPocket 11986.87 50000.0 4.171 PickPocket 6.9 43.0 92 0.043 NA NA NA NA NA NA 11986.87 50000.0 4.171 6.9 43.0 NA NA NA NA 50000.0 11986.87 43.0 6.9 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857163 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 7 6, 10 LLPLLPLLLL LLPLLLLLLG PickPocket 12249.09 29745.37 2.428 PickPocket 7.2 26.0 101 0.891 NA NA NA NA NA NA 12249.09 29745.37 2.428 7.2 26.0 NA NA NA NA 29745.37 12249.09 26.0 7.2 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 1 10 LMVCELAGNL LMVCELAGNP PickPocket 12249.09 36141.06 2.951 PickPocket 7.2 32.0 303 0.135 NA NA NA NA NA NA 12249.09 36141.06 2.951 7.2 32.0 NA NA NA NA 36141.06 12249.09 32.0 7.2 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6428571428571427 2.0714285714285716 False False False 1 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 2 9 WYQQRPGSAP WYQQRPGSSP PickPocket 12382.34 9550.53 0.771 PickPocket 7.4 4.9 7 0.571 NA NA NA NA NA NA 12382.34 9550.53 0.771 7.4 4.9 NA NA NA NA 9550.53 12382.34 4.9 7.4 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.5142857142857142 -1.5142857142857142 False False True 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 6 5 KFNPQTDYLT KFNPETDYLT PickPocket 13070.67 13212.86 1.011 PickPocket 8.1 8.2 136 0.25 NA NA NA NA NA NA 13070.67 13212.86 1.011 8.1 8.2 NA NA NA NA 13212.86 13070.67 8.2 8.1 19.ACO2.ENST00000216254.4.missense.510E/Q -1.0714285714285716 -1.0714285714285716 False False False 0 False 1 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 8 3 WTHSRDPEGS WTRSRDPEGS PickPocket 14099.07 50000.0 3.546 PickPocket 9.1 43.0 56 0.071 NA NA NA NA NA NA 14099.07 50000.0 3.546 9.1 43.0 NA NA NA NA 50000.0 14099.07 43.0 9.1 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 3 8 SVNEALNNLL SVNEALNHLL PickPocket 14099.07 15541.08 1.102 PickPocket 9.1 12.0 30 0.1 NA NA NA NA NA NA 14099.07 15541.08 1.102 9.1 12.0 NA NA NA NA 15541.08 14099.07 12.0 9.1 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.3857142857142856 0.3857142857142856 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 7 1, 2, 3 RTLLLAAAGG SRTLLAAAGG PickPocket 14564.23 50000.0 3.433 PickPocket 9.4 43.0 76 0.158 NA NA NA NA NA NA 14564.23 50000.0 3.433 9.4 43.0 NA NA NA NA 50000.0 14564.23 43.0 9.4 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.742857142857143 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 8 3 GNLFNCECDL GNPFNCECDL PickPocket 14564.23 11112.54 0.763 PickPocket 9.4 6.3 303 0.135 NA NA NA NA NA NA 14564.23 11112.54 0.763 9.4 6.3 NA NA NA NA 11112.54 14564.23 6.3 9.4 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 2 9 MVCELAGNLF MVCELAGNPF PickPocket 15044.73 13501.89 0.897 PickPocket 9.9 8.5 303 0.135 NA NA NA NA NA NA 15044.73 13501.89 0.897 9.9 8.5 NA NA NA NA 13501.89 15044.73 8.5 9.9 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 1.4714285714285713 False False False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 8 3 KVEMSHFEPN KVAMSHFEPN PickPocket 15208.39 47366.92 3.115 PickPocket 11.0 41.0 113 0.044 NA NA NA NA NA NA 15208.39 47366.92 3.115 11.0 41.0 NA NA NA NA 47366.92 15208.39 41.0 11.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 4 7 GSHVWTHSRD GSHVWTRSRD PickPocket 16053.81 17695.75 1.102 PickPocket 12.0 14.0 56 0.071 NA NA NA NA NA NA 16053.81 17695.75 1.102 12.0 14.0 NA NA NA NA 17695.75 16053.81 14.0 12.0 5.CECR2.ENST00000262608.8.missense.535R/H -1.3428571428571427 -0.7142857142857143 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 8 3 SGYESRVEPP SGSESRVEPP PickPocket 16583.46 50000.0 3.015 PickPocket 13.0 43.0 116 0.043 NA NA NA NA NA NA 16583.46 50000.0 3.015 13.0 43.0 NA NA NA NA 50000.0 16583.46 43.0 13.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.6142857142857143 -1.0142857142857145 False False True 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 6 5 HVWTHSRDPE HVWTRSRDPE PickPocket 18882.64 23699.6 1.255 PickPocket 15.0 19.0 56 0.071 NA NA NA NA NA NA 18882.64 23699.6 1.255 15.0 19.0 NA NA NA NA 23699.6 18882.64 19.0 15.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.5428571428571423 -1.3000000000000003 False False False 0 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 8 3 MDYLSDRCKI MDCLSDRCKI PickPocket 18882.64 50000.0 2.648 PickPocket 15.0 43.0 92 0.043 NA NA NA NA NA NA 18882.64 50000.0 2.648 15.0 43.0 NA NA NA NA 50000.0 18882.64 43.0 15.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857146 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 3 8 YQQRPGSAPT YQQRPGSSPT PickPocket 19088.05 18279.56 0.958 PickPocket 15.0 14.0 7 0.571 NA NA NA NA NA NA 19088.05 18279.56 0.958 15.0 14.0 NA NA NA NA 18279.56 19088.05 14.0 15.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.1142857142857143 -1.1142857142857143 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 10 1 IYGSGGYALY TYGSGGYALY PickPocket 19295.7 22451.54 1.164 PickPocket 15.0 18.0 120 0.233 NA NA NA NA NA NA 19295.7 22451.54 1.164 15.0 18.0 NA NA NA NA 22451.54 19295.7 18.0 15.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.1999999999999999 0.32857142857142857 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 2 9 YYSYGLLHIY YYSYGLLHTY PickPocket 20149.14 15881.05 0.788 PickPocket 16.0 12.0 120 0.233 NA NA NA NA NA NA 20149.14 15881.05 0.788 16.0 12.0 NA NA NA NA 15881.05 20149.14 12.0 16.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.8428571428571427 0.9142857142857143 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 4 7 SYGLLHIYGS SYGLLHTYGS PickPocket 20149.14 17505.31 0.869 PickPocket 16.0 13.0 120 0.233 NA NA NA NA NA NA 20149.14 17505.31 0.869 16.0 13.0 NA NA NA NA 17505.31 20149.14 13.0 16.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.914285714285714 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 4 7 RTEASGYESR RTEASGSESR PickPocket 20368.33 20813.9 1.022 PickPocket 16.0 17.0 116 0.043 NA NA NA NA NA NA 20368.33 20813.9 1.022 16.0 17.0 NA NA NA NA 20813.9 20368.33 17.0 16.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.3571428571428572 -1.2 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 10 2, 3 LLPLLLLLGA LPLLLLLLGA PickPocket 20589.91 50000.0 2.428 PickPocket 16.0 43.0 101 0.891 NA NA NA NA NA NA 20589.91 50000.0 2.428 16.0 43.0 NA NA NA NA 50000.0 20589.91 43.0 16.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.9142857142857146 3.028571428571429 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 10 1 VYCLQKCNVP AYCLQKCNVP PickPocket 22209.93 18082.85 0.814 PickPocket 18.0 14.0 113 0.053 NA NA NA NA NA NA 22209.93 18082.85 0.814 18.0 14.0 NA NA NA NA 18082.85 22209.93 14.0 18.0 6.USP18.ENST00000215794.7.missense.124A/V -0.28571428571428564 0.6142857142857141 False False True 2 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 3 9 ATLSRTLLLA ATLSRTLLAA PickPocket 22942.68 28485.48 1.242 PickPocket 19.0 24.0 76 0.158 NA NA NA NA NA NA 22942.68 28485.48 1.242 19.0 24.0 NA NA NA NA 28485.48 22942.68 24.0 19.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0285714285714285 1.3142857142857143 False False False 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 10 1 LFNCECDLFG PFNCECDLFG PickPocket 23192.26 50000.0 2.156 PickPocket 19.0 43.0 303 0.135 NA NA NA NA NA NA 23192.26 50000.0 2.156 19.0 43.0 NA NA NA NA 50000.0 23192.26 43.0 19.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.5999999999999999 0.5999999999999999 False False False 2 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 9 2 NLFNCECDLF NPFNCECDLF PickPocket 23699.6 50000.0 2.11 PickPocket 19.0 43.0 303 0.135 NA NA NA NA NA NA 23699.6 50000.0 2.11 19.0 43.0 NA NA NA NA 50000.0 23699.6 43.0 19.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.15714285714285708 False False False 2 True 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 6 5 GLLHIYGSGG GLLHTYGSGG PickPocket 23699.6 25564.3 1.079 PickPocket 19.0 21.0 120 0.233 NA NA NA NA NA NA 23699.6 25564.3 1.079 19.0 21.0 NA NA NA NA 25564.3 23699.6 21.0 19.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.2857142857142857 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 10 1 FTRLTSELNF STRLTSELNF PickPocket 24218.04 19932.31 0.823 PickPocket 20.0 16.0 171 0.959 NA NA NA NA NA NA 24218.04 19932.31 0.823 20.0 16.0 NA NA NA NA 19932.31 24218.04 16.0 20.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.27142857142857135 0.27142857142857135 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 1 10 SVLCQRAKVE SVLCQRAKVA PickPocket 24747.82 21269.21 0.859 PickPocket 20.0 17.0 113 0.044 NA NA NA NA NA NA 24747.82 21269.21 0.859 20.0 17.0 NA NA NA NA 21269.21 24747.82 17.0 20.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.9857142857142857 0.4999999999999999 False False False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 8 3 LAFTRLTSEL LASTRLTSEL PickPocket 24747.82 50000.0 2.02 PickPocket 20.0 43.0 171 0.959 NA NA NA NA NA NA 24747.82 50000.0 2.02 20.0 43.0 NA NA NA NA 50000.0 24747.82 43.0 20.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.3714285714285715 0.8999999999999997 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 8 3 ANQDAAQGIA ANEDAAQGIA PickPocket 25017.04 42509.45 1.699 PickPocket 21.0 37.0 22 0.5 NA NA NA NA NA NA 25017.04 42509.45 1.699 21.0 37.0 NA NA NA NA 42509.45 25017.04 37.0 21.0 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.35714285714285715 0.35714285714285715 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 6 5 EFLAFTRLTS EFLASTRLTS PickPocket 25289.19 30396.07 1.202 PickPocket 21.0 26.0 171 0.959 NA NA NA NA NA NA 25289.19 30396.07 1.202 21.0 26.0 NA NA NA NA 30396.07 25289.19 26.0 21.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.24285714285714272 1.4000000000000001 True False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 2 9 KTVTISCTGS KTVTISCTRS PickPocket 25564.3 37739.56 1.476 PickPocket 21.0 33.0 5 1.0 NA NA NA NA NA NA 25564.3 37739.56 1.476 21.0 33.0 NA NA NA NA 37739.56 25564.3 33.0 21.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5142857142857142 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 6 5 ISCTGSSGSI ISCTRSSGSI PickPocket 26407.71 31740.46 1.202 PickPocket 22.0 28.0 5 1.0 NA NA NA NA NA NA 26407.71 31740.46 1.202 22.0 28.0 NA NA NA NA 31740.46 26407.71 28.0 22.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.08571428571428566 0.5 False False False 1 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 1 10 KSPVKEEEKT KSPVKEEEKP PickPocket 26985.39 34237.82 1.269 PickPocket 23.0 30.0 185 0.038 NA NA NA NA NA NA 26985.39 34237.82 1.269 23.0 30.0 NA NA NA NA 34237.82 26985.39 30.0 23.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -1.8 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 9 2 VEMSHFEPNE VAMSHFEPNE PickPocket 27278.95 20589.91 0.755 PickPocket 23.0 16.0 113 0.044 NA NA NA NA NA NA 27278.95 20589.91 0.755 23.0 16.0 NA NA NA NA 20589.91 27278.95 16.0 23.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.9000000000000001 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 7 4 ALVRSRTYDM ALVHSRTYDM PickPocket 27875.69 26123.53 0.937 PickPocket 24.0 22.0 210 0.686 NA NA NA NA NA NA 27875.69 26123.53 0.937 24.0 22.0 NA NA NA NA 26123.53 27875.69 22.0 24.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.9142857142857144 -0.09999999999999987 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 3 8 GTLKFNPQTD GTLKFNPETD PickPocket 28178.94 28178.94 1.0 PickPocket 24.0 24.0 136 0.25 NA NA NA NA NA NA 28178.94 28178.94 1.0 24.0 24.0 NA NA NA NA 28178.94 28178.94 24.0 24.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.9857142857142855 -0.5000000000000001 False False False 0 False 1 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 9 2 AFTRLTSELN ASTRLTSELN PickPocket 28485.48 50000.0 1.755 PickPocket 24.0 43.0 171 0.959 NA NA NA NA NA NA 28485.48 50000.0 1.755 24.0 43.0 NA NA NA NA 50000.0 28485.48 43.0 24.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.7714285714285715 0.24285714285714272 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 6 7 PLLPLLPLLL PLLPLLLLLL PickPocket 29425.27 31398.89 1.067 PickPocket 25.0 27.0 101 0.891 NA NA NA NA NA NA 29425.27 31398.89 1.067 25.0 27.0 NA NA NA NA 31398.89 29425.27 27.0 25.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 10 1 RSRTYDMDVR HSRTYDMDVR PickPocket 29745.37 49461.93 1.663 PickPocket 26.0 42.0 210 0.686 NA NA NA NA NA NA 29745.37 49461.93 1.663 26.0 42.0 NA NA NA NA 49461.93 29745.37 42.0 26.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 2 9 VLCQRAKVEM VLCQRAKVAM PickPocket 30068.96 43911.91 1.46 PickPocket 26.0 38.0 113 0.044 NA NA NA NA NA NA 30068.96 43911.91 1.46 26.0 38.0 NA NA NA NA 43911.91 30068.96 38.0 26.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.0714285714285712 0.0571428571428572 False False False 1 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 3 8 AVRPLELVYC AVRPLELAYC PickPocket 30726.73 31740.46 1.033 PickPocket 26.0 28.0 113 0.053 NA NA NA NA NA NA 30726.73 31740.46 1.033 26.0 28.0 NA NA NA NA 31740.46 30726.73 28.0 26.0 6.USP18.ENST00000215794.7.missense.124A/V 1.1285714285714286 1.1285714285714286 False True False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 10 1 QTDYLTGTDG ETDYLTGTDG PickPocket 31398.89 50000.0 1.592 PickPocket 27.0 43.0 136 0.25 NA NA NA NA NA NA 31398.89 50000.0 1.592 27.0 43.0 NA NA NA NA 50000.0 31398.89 43.0 27.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.45714285714285713 -0.45714285714285713 True False False 0 False 0 NA NA NA NA -22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-G*01:09 10 10 10 FNMSSFKLKQ FNMSSFKLKE PickPocket 31740.46 29425.27 0.927 PickPocket 28.0 25.0 117 0.496 NA NA NA NA NA NA 31740.46 29425.27 0.927 28.0 25.0 NA NA NA NA 29425.27 31740.46 25.0 28.0 14.LGALS2.ENST00000215886.4.missense.132E/Q -0.9000000000000001 -0.07142857142857155 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 5 6 VSPEPARPPQ VSPEPPRPPQ PickPocket 31740.46 32787.64 1.033 PickPocket 28.0 29.0 245 0.486 NA NA NA NA NA NA 31740.46 32787.64 1.033 28.0 29.0 NA NA NA NA 32787.64 31740.46 29.0 28.0 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -0.8571428571428571 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 7 4 VWTHSRDPEG VWTRSRDPEG PickPocket 32085.75 34237.82 1.067 PickPocket 28.0 30.0 56 0.071 NA NA NA NA NA NA 32085.75 34237.82 1.067 28.0 30.0 NA NA NA NA 34237.82 32085.75 30.0 28.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.5 -1.3428571428571427 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 7 4 ALNNLLTEEE ALNHLLTEEE PickPocket 32085.75 33869.37 1.056 PickPocket 28.0 30.0 30 0.1 NA NA NA NA NA NA 32085.75 33869.37 1.056 28.0 30.0 NA NA NA NA 33869.37 32085.75 30.0 28.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.7857142857142856 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 9 1 LLLAAAGGSS TLLAAAGGSS PickPocket 32434.8 32787.64 1.011 PickPocket 28.0 29.0 76 0.158 NA NA NA NA NA NA 32434.8 32787.64 1.011 28.0 29.0 NA NA NA NA 32787.64 32434.8 29.0 28.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 0.42857142857142855 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 7 4 FNPQTDYLTG FNPETDYLTG PickPocket 33869.37 31060.99 0.917 PickPocket 30.0 27.0 136 0.25 NA NA NA NA NA NA 33869.37 31060.99 0.917 30.0 27.0 NA NA NA NA 31060.99 33869.37 27.0 30.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9000000000000001 -0.9000000000000001 False False False 0 False 1 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 4 7 VRPLELVYCL VRPLELAYCL PickPocket 34986.78 35367.39 1.011 PickPocket 31.0 31.0 113 0.053 NA NA NA NA NA NA 34986.78 35367.39 1.011 31.0 31.0 NA NA NA NA 35367.39 34986.78 31.0 31.0 6.USP18.ENST00000215794.7.missense.124A/V 1.9000000000000001 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 5 6 LKFNPQTDYL LKFNPETDYL PickPocket 34986.78 36931.66 1.056 PickPocket 31.0 32.0 136 0.25 NA NA NA NA NA NA 34986.78 36931.66 1.056 31.0 32.0 NA NA NA NA 36931.66 34986.78 32.0 31.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.4714285714285715 -0.942857142857143 False False False 0 False 1 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 8 1, 2 TLLLAAAGGS RTLLAAAGGS PickPocket 36931.66 14099.07 0.382 PickPocket 32.0 9.1 76 0.158 NA NA NA NA NA NA 36931.66 14099.07 0.382 32.0 9.1 NA NA NA NA 14099.07 36931.66 9.1 32.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0857142857142856 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 6 5 LIGKHGGVSL LIGKPGGVSL PickPocket 36931.66 43439.36 1.176 PickPocket 32.0 38.0 140 0.179 NA NA NA NA NA NA 36931.66 43439.36 1.176 32.0 38.0 NA NA NA NA 43439.36 36931.66 38.0 32.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.10000000000000002 0.05714285714285713 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 3 8 SLFGALVRSR SLFGALVHSR PickPocket 37333.42 35752.13 0.958 PickPocket 33.0 31.0 210 0.686 NA NA NA NA NA NA 37333.42 35752.13 0.958 33.0 31.0 NA NA NA NA 35752.13 37333.42 31.0 33.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.05714285714285732 2.1714285714285713 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 16 NA SGEKAGCPWS NA PickPocket 37739.56 NA NA PickPocket 33.0 NA 142 0.768 NA NA NA NA NA NA 37739.56 NA NA 33.0 NA NA NA NA NA NA 37739.56 NA 33.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 9 2 TTQKRNSRRQ TAQKRNSRRQ PickPocket 37739.56 50000.0 1.325 PickPocket 33.0 43.0 96 0.042 NA NA NA NA NA NA 37739.56 50000.0 1.325 33.0 43.0 NA NA NA NA 50000.0 37739.56 43.0 33.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6000000000000005 -2.5142857142857147 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 1 10 LHHEDLIGKH LHHEDLIGKP PickPocket 38150.11 38565.12 1.011 PickPocket 33.0 34.0 140 0.179 NA NA NA NA NA NA 38150.11 38565.12 1.011 33.0 34.0 NA NA NA NA 38565.12 38150.11 34.0 33.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.8857142857142858 -0.18571428571428594 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 9 2 SAPTTVIYED SSPTTVIYED PickPocket 38565.12 21734.48 0.564 PickPocket 34.0 18.0 7 0.571 NA NA NA NA NA NA 38565.12 21734.48 0.564 34.0 18.0 NA NA NA NA 21734.48 38565.12 18.0 34.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.14285714285714274 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 3 8 KTTVVVTTQK KTTVVVTAQK PickPocket 38984.65 40708.92 1.044 PickPocket 34.0 35.0 96 0.042 NA NA NA NA NA NA 38984.65 40708.92 1.044 34.0 35.0 NA NA NA NA 40708.92 38984.65 35.0 34.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 0.5428571428571433 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 5 6 RPLELVYCLQ RPLELAYCLQ PickPocket 40708.92 44389.61 1.09 PickPocket 35.0 39.0 113 0.053 NA NA NA NA NA NA 40708.92 44389.61 1.09 35.0 39.0 NA NA NA NA 44389.61 40708.92 39.0 35.0 6.USP18.ENST00000215794.7.missense.124A/V 0.8571428571428571 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 2 9 ALGWEFLAFT ALGWEFLAST PickPocket 41151.77 50000.0 1.215 PickPocket 36.0 43.0 171 0.959 NA NA NA NA NA NA 41151.77 50000.0 1.215 36.0 43.0 NA NA NA NA 50000.0 41151.77 43.0 36.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.8714285714285712 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 1 10 RSGGSHVWTH RSGGSHVWTR PickPocket 41599.44 50000.0 1.202 PickPocket 36.0 43.0 56 0.071 NA NA NA NA NA NA 41599.44 50000.0 1.202 36.0 43.0 NA NA NA NA 50000.0 41599.44 43.0 36.0 5.CECR2.ENST00000262608.8.missense.535R/H -0.7142857142857143 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 20 NA AGCPWSGTGQ NA PickPocket 41599.44 NA NA PickPocket 36.0 NA 142 0.768 NA NA NA NA NA NA 41599.44 NA NA 36.0 NA NA NA NA NA NA 41599.44 NA 36.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.1857142857142857 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 1 10 REERTEASGY REERTEASGS PickPocket 41599.44 46857.18 1.126 PickPocket 36.0 41.0 116 0.043 NA NA NA NA NA NA 41599.44 46857.18 1.126 36.0 41.0 NA NA NA NA 46857.18 41599.44 41.0 36.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.342857142857143 -1.342857142857143 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 10 1 NLLTEEEDYQ HLLTEEEDYQ PickPocket 42509.45 21970.92 0.517 PickPocket 37.0 18.0 30 0.1 NA NA NA NA NA NA 42509.45 21970.92 0.517 37.0 18.0 NA NA NA NA 21970.92 42509.45 18.0 37.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -2.7857142857142856 -1.0142857142857145 False False False 0 True 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 9 2 KHGGVSLSKI KPGGVSLSKI PickPocket 42971.89 50000.0 1.164 PickPocket 37.0 43.0 140 0.179 NA NA NA NA NA NA 42971.89 50000.0 1.164 37.0 43.0 NA NA NA NA 50000.0 42971.89 43.0 37.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.9428571428571428 0.9428571428571428 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 4 7 QQRPGSAPTT QQRPGSSPTT PickPocket 43439.36 42051.98 0.968 PickPocket 38.0 37.0 7 0.571 NA NA NA NA NA NA 43439.36 42051.98 0.968 38.0 37.0 NA NA NA NA 42051.98 43439.36 37.0 38.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5714285714285714 -0.5714285714285714 True False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 5 6 QRPGSAPTTV QRPGSSPTTV PickPocket 44389.61 43439.36 0.979 PickPocket 39.0 38.0 7 0.571 NA NA NA NA NA NA 44389.61 43439.36 0.979 39.0 38.0 NA NA NA NA 43439.36 44389.61 38.0 39.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.2571428571428571 0.2571428571428571 True False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 7 NA RSAGSTGQGS NA PickPocket 44389.61 NA NA PickPocket 39.0 NA 142 0.768 NA NA NA NA NA NA 44389.61 NA NA 39.0 NA NA NA NA NA NA 44389.61 NA 39.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 4 7 VNEALNNLLT VNEALNHLLT PickPocket 45360.65 45854.11 1.011 PickPocket 39.0 40.0 30 0.1 NA NA NA NA NA NA 45360.65 45854.11 1.011 39.0 40.0 NA NA NA NA 45854.11 45360.65 40.0 39.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.7857142857142856 0.7857142857142856 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 2 9 HHEDLIGKHG HHEDLIGKPG PickPocket 45360.65 36141.06 0.797 PickPocket 39.0 32.0 140 0.179 NA NA NA NA NA NA 45360.65 36141.06 0.797 39.0 32.0 NA NA NA NA 36141.06 45360.65 32.0 39.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.44285714285714295 -0.44285714285714295 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 8 3 LHIYGSGGYA LHTYGSGGYA PickPocket 45360.65 50000.0 1.102 PickPocket 39.0 43.0 120 0.233 NA NA NA NA NA NA 45360.65 50000.0 1.102 39.0 43.0 NA NA NA NA 50000.0 45360.65 43.0 39.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.39999999999999997 0.3142857142857142 False False False 0 False 0 NA NA NA NA -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 5 6 YGLLHIYGSG YGLLHTYGSG PickPocket 46352.93 42509.45 0.917 PickPocket 40.0 37.0 120 0.233 NA NA NA NA NA NA 46352.93 42509.45 0.917 40.0 37.0 NA NA NA NA 42509.45 46352.93 37.0 40.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.3142857142857142 0.9714285714285714 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 21 NA GCPWSGTGQH NA PickPocket 47882.2 NA NA PickPocket 41.0 NA 142 0.768 NA NA NA NA NA NA 47882.2 NA NA 41.0 NA NA NA NA NA NA 47882.2 NA 41.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.4142857142857141 -0.32857142857142857 False False False 1 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 6 5 RPGSAPTTVI RPGSSPTTVI PickPocket 48403.09 50000.0 1.033 PickPocket 42.0 43.0 7 0.571 NA NA NA NA NA NA 48403.09 50000.0 1.033 42.0 43.0 NA NA NA NA 50000.0 48403.09 43.0 42.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.9571428571428572 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 10 1 TQKRNSRRQL AQKRNSRRQL PickPocket 48403.09 41599.44 0.859 PickPocket 42.0 36.0 96 0.042 NA NA NA NA NA NA 48403.09 41599.44 0.859 42.0 36.0 NA NA NA NA 41599.44 48403.09 36.0 42.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -2.5 -2.5 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 2 9 VSLFGALVRS VSLFGALVHS PickPocket 48929.64 42971.89 0.878 PickPocket 42.0 37.0 210 0.686 NA NA NA NA NA NA 48929.64 42971.89 0.878 42.0 37.0 NA NA NA NA 42971.89 48929.64 37.0 42.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R 0.9857142857142857 2.1714285714285713 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 4 7 VTISCTGSSG VTISCTRSSG PickPocket 49461.93 50000.0 1.011 PickPocket 42.0 43.0 5 1.0 NA NA NA NA NA NA 49461.93 50000.0 1.011 42.0 43.0 NA NA NA NA 50000.0 49461.93 43.0 42.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.19999999999999998 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 3 8 LCQRAKVEMS LCQRAKVAMS PickPocket 49461.93 50000.0 1.011 PickPocket 42.0 43.0 113 0.044 NA NA NA NA NA NA 49461.93 50000.0 1.011 42.0 43.0 NA NA NA NA 50000.0 49461.93 43.0 42.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.6857142857142857 0.0571428571428572 False False False 1 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 3 10 PPPPLLPLLP PPPPLLPLLL PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.4857142857142858 1.4857142857142858 False False True 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 4 9 PPPLLPLLPL PPPLLPLLLL PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 5 8 PPLLPLLPLL PPLLPLLLLL PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 8 1, 2, 4, 5 LPLLPLLLLL PLLPLLLLLL PickPocket 50000.0 31398.89 0.628 PickPocket 43.0 27.0 101 0.891 NA NA NA NA NA NA 50000.0 31398.89 0.628 43.0 27.0 NA NA NA NA 31398.89 50000.0 27.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 9 1, 3, 4 PLLPLLLLLG LLPLLLLLLG PickPocket 50000.0 29745.37 0.595 PickPocket 43.0 26.0 101 0.891 NA NA NA NA NA NA 50000.0 29745.37 0.595 43.0 26.0 NA NA NA NA 29745.37 50000.0 26.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.4285714285714293 3.028571428571429 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 11 1, 2 LPLLLLLGAS PLLLLLLGAS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.2571428571428567 3.028571428571429 False False False 0 False 0 NA NA NA NA -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 12 1 PLLLLLGASG LLLLLLGASG PickPocket 50000.0 39837.46 0.797 PickPocket 43.0 35.0 101 0.891 NA NA NA NA NA NA 50000.0 39837.46 0.797 43.0 35.0 NA NA NA NA 39837.46 50000.0 35.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.6571428571428568 2.9142857142857146 False False False 0 False 0 NA NA NA NA -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-G*01:09 10 2 10 ASAAAAAAAV ASAAAAAAAA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 128 0.977 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.142857142857143 2.142857142857143 False False False 0 False 0 NA NA NA NA -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-G*01:09 10 3 1 SAAAAAAAVI AAAAAAAAVI PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 128 0.977 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.5285714285714285 2.5285714285714285 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 2 10 SATLSRTLLL SATLSRTLLA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.3142857142857143 1.3142857142857143 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 4 8 TLSRTLLLAA TLSRTLLAAA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.4 1.4 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 5 7, 10 LSRTLLLAAA LSRTLLAAAG PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.3000000000000003 2.3000000000000003 False False False 0 False 0 NA NA NA NA -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 6 1, 2, 3, 4 SRTLLLAAAG LSRTLLAAAG PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.342857142857143 2.342857142857143 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 2 9 SGGSHVWTHS SGGSHVWTRS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H -0.7714285714285714 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 3 8 GGSHVWTHSR GGSHVWTRSR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H -1.3000000000000003 -0.31428571428571433 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 5 6 SHVWTHSRDP SHVWTRSRDP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1714285714285717 -0.7714285714285714 False False True 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 9 2 THSRDPEGSS TRSRDPEGSS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 10 1 HSRDPEGSSR RSRDPEGSSR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 1 10 QKAVRPLELV QKAVRPLELA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V 0.9142857142857144 0.9142857142857144 True False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 2 9 KAVRPLELVY KAVRPLELAY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V 0.1285714285714286 0.9142857142857144 False False False 0 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 6 5 PLELVYCLQK PLELAYCLQK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V 0.7999999999999999 1.9000000000000001 False False False 1 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 7 4 LELVYCLQKC LELAYCLQKC PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V 0.6142857142857141 1.9000000000000001 False True False 2 False 0 NA NA NA NA -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 8 3 ELVYCLQKCN ELAYCLQKCN PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V -0.4857142857142857 0.8571428571428571 True False False 2 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 1 10 NKSVNEALNN NKSVNEALNH PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6 -0.21428571428571427 False False False 0 True 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 5 6 NEALNNLLTE NEALNHLLTE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.02857142857142847 0.7857142857142856 False False False 0 True 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 6 5 EALNNLLTEE EALNHLLTEE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.7857142857142856 True False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 8 3 LNNLLTEEED LNHLLTEEED PickPocket 50000.0 22451.54 0.449 PickPocket 43.0 18.0 30 0.1 NA NA NA NA NA NA 50000.0 22451.54 0.449 43.0 18.0 NA NA NA NA 22451.54 50000.0 18.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.02857142857142847 False False False 0 False 0 NA NA NA NA -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 9 2 NNLLTEEEDY NHLLTEEEDY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.742857142857143 -1.0142857142857145 False False False 0 True 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 1 10 EDAVQGIANQ EDAVQGIANE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.0571428571428572 0.7000000000000001 True False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 2 9 DAVQGIANQD DAVQGIANED PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.157142857142857 0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 4 7 VQGIANQDAA VQGIANEDAA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.08571428571428576 -0.0571428571428572 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 5 6 QGIANQDAAQ QGIANEDAAQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.2285714285714284 -0.08571428571428576 True False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 6 5 GIANQDAAQG GIANEDAAQG PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.5428571428571427 -0.08571428571428576 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 7 4 IANQDAAQGI IANEDAAQGI PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 -0.08571428571428576 False False False 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 9 2 NQDAAQGIAK NEDAAQGIAK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.3 0.35714285714285715 False False False 0 True 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 10 1 QDAAQGIAKE EDAAQGIAKE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.45714285714285713 0.35714285714285715 True False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 1 10 GKTVTISCTG GKTVTISCTR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 1.2285714285714284 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 3 8 TVTISCTGSS TVTISCTRSS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5 1.2285714285714284 False False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 5 6 TISCTGSSGS TISCTRSSGS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.20000000000000004 0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 7 4 SCTGSSGSIA SCTRSSGSIA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.4428571428571428 0.4428571428571428 False False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 8 3 CTGSSGSIAS CTRSSGSIAS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.38571428571428573 0.4428571428571428 True False False 1 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 9 2 TGSSGSIASN TRSSGSIASN PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.0 0.4428571428571428 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 10 1 GSSGSIASNY RSSGSIASNY PickPocket 50000.0 33504.88 0.67 PickPocket 43.0 29.0 5 1.0 NA NA NA NA NA NA 50000.0 33504.88 0.67 43.0 29.0 NA NA NA NA 33504.88 50000.0 29.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.07142857142857147 0.4428571428571428 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 7 4 PGSAPTTVIY PGSSPTTVIY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.8857142857142858 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 8 3 GSAPTTVIYE GSSPTTVIYE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.12857142857142861 0.9571428571428572 False False False 0 False 0 NA NA NA NA -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 10 1 APTTVIYEDN SPTTVIYEDN PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5428571428571428 0.8857142857142858 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 3 8 HEDLIGKHGG HEDLIGKPGG PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H -3.172065784643304e-17 -3.172065784643304e-17 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 4 7 EDLIGKHGGV EDLIGKPGGV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.05714285714285713 0.05714285714285713 True False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 5 6 DLIGKHGGVS DLIGKPGGVS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H -0.7000000000000001 0.05714285714285713 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 7 4 IGKHGGVSLS IGKPGGVSLS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.3428571428571429 0.3428571428571429 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 8 3 GKHGGVSLSK GKPGGVSLSK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.24285714285714294 0.3428571428571429 False False False 0 False 0 NA NA NA NA -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 10 1 HGGVSLSKIE PGGVSLSKIE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H 0.5 0.9428571428571428 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 2 9 SPVKEEEKTQ SPVKEEEKPQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T -3.2142857142857144 -1.8 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 3 8 PVKEEEKTQE PVKEEEKPQE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T -3.1571428571428575 -2.1142857142857143 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 4 7 VKEEEKTQEV VKEEEKPQEV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.0571428571428574 -2.0571428571428574 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 5 6 KEEEKTQEVK KEEEKPQEVK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -2.0571428571428574 False False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 6 5 EEEKTQEVKV EEEKPQEVKV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.014285714285714 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 7 4 EEKTQEVKVK EEKPQEVKVK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.0142857142857142 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 8 3 EKTQEVKVKE EKPQEVKVKE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T -1.4142857142857141 -1.014285714285714 True False False 0 False 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 10 1 TQEVKVKEPP PQEVKVKEPP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T -0.8714285714285713 -0.8714285714285713 False False True 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 3 8 VCELAGNLFN VCELAGNPFN PickPocket 50000.0 43911.91 0.878 PickPocket 43.0 38.0 303 0.135 NA NA NA NA NA NA 50000.0 43911.91 0.878 43.0 38.0 NA NA NA NA 43911.91 50000.0 38.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 0.7000000000000001 False False False 1 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 4 7 CELAGNLFNC CELAGNPFNC PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.5 0.6857142857142856 True True False 2 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 5 6 ELAGNLFNCE ELAGNPFNCE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L -0.2571428571428572 0.6857142857142856 True False False 1 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 6 5 LAGNLFNCEC LAGNPFNCEC PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.6857142857142856 False True False 2 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 7 4 AGNLFNCECD AGNPFNCECD PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.5 False False False 2 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 2 9 LHTVSPEPAR LHTVSPEPPR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A -0.8571428571428571 -0.2571428571428572 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 3 8 HTVSPEPARP HTVSPEPPRP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.6857142857142855 -0.31428571428571433 False False True 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 4 7 TVSPEPARPP TVSPEPPRPP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.7999999999999996 -0.31428571428571433 False False True 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 6 5 SPEPARPPQQ SPEPPRPPQQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -1.6857142857142855 False False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 7 4 PEPARPPQQP PEPPRPPQQP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -1.7999999999999996 False False True 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 8 3 EPARPPQQPV EPPRPPQQPV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.7285714285714289 -1.7285714285714289 True False False 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 9 2 PARPPQQPVP PPRPPQQPVP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 NA NA NA NA -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 10 1 ARPPQQPVPT PRPPQQPVPT PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A -1.1857142857142855 -1.1857142857142855 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 2 10 TGGGGRSAGS TGGGGRSAGQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.7285714285714285 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 3 9, 10 GGGGRSAGST GGGGRSAGQH PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7285714285714285 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 4 8, 9, 10 GGGRSAGSTG GGGRSAGQHW PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7285714285714286 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 5 7, 8, 9, 10 GGRSAGSTGQ GGRSAGQHWA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6857142857142857 -0.6857142857142857 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 6 6, 7, 8, 9, 10 GRSAGSTGQG GRSAGQHWAR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6285714285714287 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 8 NA SAGSTGQGSG NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 9 NA AGSTGQGSGE NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.3857142857142857 -0.6285714285714287 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 10 NA GSTGQGSGEK NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.842857142857143 -1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 11 NA STGQGSGEKA NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.5285714285714287 -1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 12 NA TGQGSGEKAG NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0857142857142859 -1.0857142857142859 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 13 NA GQGSGEKAGC NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6714285714285715 -0.6714285714285715 False True False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 14 NA QGSGEKAGCP NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.6714285714285715 True False True 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 15 NA GSGEKAGCPW NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8571428571428574 -0.6714285714285715 False False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 17 NA GEKAGCPWSG NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G 0.02857142857142855 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 18 NA EKAGCPWSGT NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.32857142857142857 0.02857142857142855 True False False 1 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 19 NA KAGCPWSGTG NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.3285714285714286 0.02857142857142855 False False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 3 8 QPCDDMDYLS QPCDDMDCLS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142858 -0.5142857142857142 True False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 4 7 PCDDMDYLSD PCDDMDCLSD PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142857 -0.5142857142857142 False False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 5 6 CDDMDYLSDR CDDMDCLSDR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.1285714285714286 -0.5142857142857142 True False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 6 5 DDMDYLSDRC DDMDCLSDRC PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.042857142857143 -0.9857142857142857 False True False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 7 4 DMDYLSDRCK DMDCLSDRCK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.0999999999999999 -0.9857142857142857 False False False 1 False 0 NA NA NA NA -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 10 1 YLSDRCKILQ CLSDRCKILQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.6571428571428573 -0.27142857142857146 False False False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 4 7 CQRAKVEMSH CQRAKVAMSH PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.044 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.5 -0.5 True False False 1 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 5 6 QRAKVEMSHF QRAKVAMSHF PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.044 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.35714285714285715 -0.35714285714285715 True False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 6 5 RAKVEMSHFE RAKVAMSHFE PickPocket 50000.0 49461.93 0.989 PickPocket 43.0 42.0 113 0.044 NA NA NA NA NA NA 50000.0 49461.93 0.989 43.0 42.0 NA NA NA NA 49461.93 50000.0 42.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E -0.3000000000000001 -0.3000000000000001 False False False 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 7 4 AKVEMSHFEP AKVAMSHFEP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.044 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 -0.3000000000000001 False False True 0 False 0 NA NA NA NA -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 10 1 EMSHFEPNEY AMSHFEPNEY PickPocket 50000.0 36141.06 0.723 PickPocket 43.0 32.0 113 0.044 NA NA NA NA NA NA 50000.0 36141.06 0.723 43.0 32.0 NA NA NA NA 36141.06 50000.0 32.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E -1.9714285714285715 -1.1285714285714286 True False False 0 False 0 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 1 10 IAGTLKFNPQ IAGTLKFNPE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 1.1285714285714286 False False False 0 False 1 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 2 9 AGTLKFNPQT AGTLKFNPET PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 -0.0142857142857143 False False False 0 False 1 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 4 7 TLKFNPQTDY TLKFNPETDY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q -1.6142857142857143 -0.942857142857143 False False False 0 False 1 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 8 3 NPQTDYLTGT NPETDYLTGT PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.5 -0.5 False False False 0 True 1 NA NA NA NA -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 9 2 PQTDYLTGTD PETDYLTGTD PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9 -0.5 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 1 10 SAKTTVVVTT SAKTTVVVTA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.4000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 2 9 AKTTVVVTTQ AKTTVVVTAQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.0000000000000002 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 4 7 TTVVVTTQKR TTVVVTAQKR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -0.7000000000000001 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 5 6 TVVVTTQKRN TVVVTAQKRN PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -1.8 1.0000000000000002 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 6 5 VVVTTQKRNS VVVTAQKRNS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -2.5142857142857147 0.5428571428571433 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 7 4 VVTTQKRNSR VVTAQKRNSR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.0571428571428574 -0.7000000000000001 False False False 0 False 0 NA NA NA NA -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 8 3 VTTQKRNSRR VTAQKRNSRR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6 -1.8 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 1 10 PALGWEFLAF PALGWEFLAS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 171 0.959 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.9142857142857143 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 3 8 LGWEFLAFTR LGWEFLASTR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 171 0.959 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.35714285714285704 1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 5 6 WEFLAFTRLT WEFLASTRLT PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 171 0.959 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 22.PANX2.ENST00000395842.2.missense.147S/F 0.8999999999999997 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 7 4 FLAFTRLTSE FLASTRLTSE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 171 0.959 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 22.PANX2.ENST00000395842.2.missense.147S/F -0.5142857142857143 1.4000000000000001 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 1 10 RVSLFGALVR RVSLFGALVH PickPocket 50000.0 39837.46 0.797 PickPocket 43.0 35.0 210 0.686 NA NA NA NA NA NA 50000.0 39837.46 0.797 43.0 35.0 NA NA NA NA 39837.46 50000.0 35.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R 1.6428571428571428 2.1714285714285713 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 4 7 LFGALVRSRT LFGALVHSRT PickPocket 50000.0 45360.65 0.907 PickPocket 43.0 39.0 210 0.686 NA NA NA NA NA NA 50000.0 45360.65 0.907 43.0 39.0 NA NA NA NA 45360.65 50000.0 39.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.09999999999999987 1.6428571428571428 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 5 6 FGALVRSRTY FGALVHSRTY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.5428571428571428 0.9857142857142857 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 6 5 GALVRSRTYD GALVHSRTYD PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.5857142857142856 -0.05714285714285732 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 8 3 LVRSRTYDMD LVHSRTYDMD PickPocket 50000.0 15541.08 0.311 PickPocket 43.0 12.0 210 0.686 NA NA NA NA NA NA 50000.0 15541.08 0.311 43.0 12.0 NA NA NA NA 15541.08 50000.0 12.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.7714285714285716 -0.5428571428571428 False False False 0 False 0 NA NA NA NA -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 9 2 VRSRTYDMDV VHSRTYDMDV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 2 9 EERTEASGYE EERTEASGSE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2 -1.2 True False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 3 8 ERTEASGYES ERTEASGSES PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2142857142857142 -1.2 True False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 5 6 TEASGYESRV TEASGSESRV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.0142857142857145 -1.0142857142857145 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 6 5 EASGYESRVE EASGSESRVE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.4000000000000001 -1.0142857142857145 True False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 7 4 ASGYESRVEP ASGSESRVEP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285712 -1.0142857142857145 False False True 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 10 1 YESRVEPPHE SESRVEPPHE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.957142857142857 -1.5714285714285712 False False False 0 False 0 NA NA NA NA -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 9 7 GWEFLAFTRLTSELN GWEFLASTRLTSELN NNalign 16.2 15.4 0.951 NNalign 1.6 1.4 171 0.959 NA NA NA NA NA NA 16.2 15.4 0.951 1.6 1.4 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F -0.7714285714285715 1.4000000000000001 False False False 0 False 0 15.4 16.2 1.4 1.6 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 10 6 WEFLAFTRLTSELNF WEFLASTRLTSELNF NNalign 17.5 17.2 0.983 NNalign 1.7 1.7 171 0.959 NA NA NA NA NA NA 17.5 17.2 0.983 1.7 1.7 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.27142857142857135 1.4000000000000001 False False False 0 False 0 17.2 17.5 1.7 1.7 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 9 7 TTVVVTTQKRNSRRQ TTVVVTAQKRNSRRQ NNalign 18.2 15.0 0.824 NNalign 1.8 1.4 96 0.042 NA NA NA NA NA NA 18.2 15.0 0.824 1.8 1.4 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6000000000000005 1.4000000000000001 False False False 0 False 0 15.0 18.2 1.4 1.8 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 8 8 LGWEFLAFTRLTSEL LGWEFLASTRLTSEL NNalign 18.6 16.6 0.892 NNalign 1.8 1.6 171 0.959 NA NA NA NA NA NA 18.6 16.6 0.892 1.8 1.6 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F -0.3714285714285715 1.4000000000000001 False False False 0 False 0 16.6 18.6 1.6 1.8 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 10 6 TVVVTTQKRNSRRQL TVVVTAQKRNSRRQL NNalign 19.2 14.7 0.766 NNalign 1.9 1.4 96 0.042 NA NA NA NA NA NA 19.2 14.7 0.766 1.9 1.4 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -2.5 1.0000000000000002 False False False 0 False 0 14.7 19.2 1.4 1.9 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 8 8 KTTVVVTTQKRNSRR KTTVVVTAQKRNSRR NNalign 20.8 16.7 0.803 NNalign 2.1 1.6 96 0.042 NA NA NA NA NA NA 20.8 16.7 0.803 2.1 1.6 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6 1.4000000000000001 False False False 0 False 0 16.7 20.8 1.6 2.1 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 7 9 ALGWEFLAFTRLTSE ALGWEFLASTRLTSE NNalign 22.6 20.3 0.898 NNalign 2.3 2.0 171 0.959 NA NA NA NA NA NA 22.6 20.3 0.898 2.3 2.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F -0.5142857142857143 1.4000000000000001 False False False 0 False 0 20.3 22.6 2.0 2.3 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 11 5 EFLAFTRLTSELNFL EFLASTRLTSELNFL NNalign 27.0 39.5 1.463 NNalign 2.7 4.1 171 0.959 NA NA NA NA NA NA 27.0 39.5 1.463 2.7 4.1 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.27142857142857135 1.4000000000000001 True False False 0 False 0 39.5 27.0 4.1 2.7 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 8 8 SLFGALVRSRTYDMD SLFGALVHSRTYDMD NNalign 31.0 168.6 5.439 NNalign 3.2 14.0 210 0.686 NA NA NA NA NA NA 31.0 168.6 5.439 3.2 14.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.7714285714285716 2.1714285714285713 False False False 0 False 0 168.6 31.0 14.0 3.2 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 7 9 VSLFGALVRSRTYDM VSLFGALVHSRTYDM NNalign 32.0 159.8 4.994 NNalign 3.3 13.0 210 0.686 NA NA NA NA NA NA 32.0 159.8 4.994 3.3 13.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.9142857142857144 2.1714285714285713 False False False 0 False 0 159.8 32.0 13.0 3.3 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 6 10 RVSLFGALVRSRTYD RVSLFGALVHSRTYD NNalign 35.5 162.9 4.589 NNalign 3.6 13.0 210 0.686 NA NA NA NA NA NA 35.5 162.9 4.589 3.6 13.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.5857142857142856 2.1714285714285713 False False False 0 False 0 162.9 35.5 13.0 3.6 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 6 10 PALGWEFLAFTRLTS PALGWEFLASTRLTS NNalign 36.1 33.2 0.92 NNalign 3.7 3.4 171 0.959 NA NA NA NA NA NA 36.1 33.2 0.92 3.7 3.4 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.24285714285714272 1.4000000000000001 False False False 0 False 0 33.2 36.1 3.4 3.7 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 5 11 TRVSLFGALVRSRTY TRVSLFGALVHSRTY NNalign 37.4 166.1 4.441 NNalign 3.8 13.0 210 0.686 NA NA NA NA NA NA 37.4 166.1 4.441 3.8 13.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.5428571428571428 2.1714285714285713 False False False 0 False 0 166.1 37.4 13.0 3.8 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 11 5 VVVTTQKRNSRRQLP VVVTAQKRNSRRQLP NNalign 39.4 34.9 0.886 NNalign 4.1 3.5 96 0.042 NA NA NA NA NA NA 39.4 34.9 0.886 4.1 3.5 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -2.085714285714286 0.5428571428571433 False False True 0 False 0 34.9 39.4 3.5 4.1 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 7 9 AKTTVVVTTQKRNSR AKTTVVVTAQKRNSR NNalign 40.3 32.4 0.804 NNalign 4.2 3.3 96 0.042 NA NA NA NA NA NA 40.3 32.4 0.804 4.2 3.3 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.0571428571428574 1.4000000000000001 False False False 0 False 0 32.4 40.3 3.3 4.2 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 12 4 FLAFTRLTSELNFLL FLASTRLTSELNFLL NNalign 47.8 159.1 3.328 NNalign 4.8 13.0 171 0.959 NA NA NA NA NA NA 47.8 159.1 3.328 4.8 13.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.9142857142857143 1.4000000000000001 False False False 0 False 0 159.1 47.8 13.0 4.8 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 9 7 LFGALVRSRTYDMDV LFGALVHSRTYDMDV NNalign 55.5 318.2 5.733 NNalign 5.4 19.0 210 0.686 NA NA NA NA NA NA 55.5 318.2 5.733 5.4 19.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.0571428571428572 1.6428571428571428 False False False 0 False 0 318.2 55.5 19.0 5.4 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 4 12 DTRVSLFGALVRSRT DTRVSLFGALVHSRT NNalign 78.7 317.5 4.034 NNalign 7.4 19.0 210 0.686 NA NA NA NA NA NA 78.7 317.5 4.034 7.4 19.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.09999999999999987 2.1714285714285713 False False False 0 False 0 317.5 78.7 19.0 7.4 -22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-DRB1*11:01 15 15 15 SVRGGFNMSSFKLKQ SVRGGFNMSSFKLKE NNalign 123.2 223.9 1.817 NNalign 11.0 16.0 117 0.496 NA NA NA NA NA NA 123.2 223.9 1.817 11.0 16.0 NA NA NA NA NA NA NA NA 14.LGALS2.ENST00000215886.4.missense.132E/Q -0.9000000000000001 0.28571428571428564 False False False 0 False 0 223.9 123.2 16.0 11.0 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 10 6 FGALVRSRTYDMDVR FGALVHSRTYDMDVR NNalign 125.8 662.4 5.266 NNalign 11.0 29.0 210 0.686 NA NA NA NA NA NA 125.8 662.4 5.266 11.0 29.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.0571428571428572 0.9857142857142857 False False False 0 False 0 662.4 125.8 29.0 11.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 6 10 SAKTTVVVTTQKRNS SAKTTVVVTAQKRNS NNalign 142.1 111.5 0.785 NNalign 12.0 9.6 96 0.042 NA NA NA NA NA NA 142.1 111.5 0.785 12.0 9.6 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -2.5142857142857147 1.4000000000000001 False False False 0 False 0 111.5 142.1 9.6 12.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 12 4 VVTTQKRNSRRQLPS VVTAQKRNSRRQLPS NNalign 171.9 154.3 0.898 NNalign 14.0 13.0 96 0.042 NA NA NA NA NA NA 171.9 154.3 0.898 14.0 13.0 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -1.7 -0.7000000000000001 False False False 0 False 0 154.3 171.9 13.0 14.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 1 15 QYHVASVLCQRAKVE QYHVASVLCQRAKVA NNalign 202.2 164.8 0.815 NNalign 15.0 13.0 113 0.044 NA NA NA NA NA NA 202.2 164.8 0.815 15.0 13.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -0.9857142857142857 1.7857142857142858 True False False 1 False 0 164.8 202.2 13.0 15.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 15 1 HGGVSLSKIERSTDQ PGGVSLSKIERSTDQ NNalign 203.3 232.4 1.143 NNalign 15.0 16.0 140 0.179 NA NA NA NA NA NA 203.3 232.4 1.143 15.0 16.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -1.7142857142857142 0.9428571428571428 False False False 0 False 0 232.4 203.3 16.0 15.0 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 13 3 LAFTRLTSELNFLLQ LASTRLTSELNFLLQ NNalign 203.3 6175.2 30.375 NNalign 15.0 72.0 171 0.959 NA NA NA NA NA NA 203.3 6175.2 30.375 15.0 72.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.5285714285714285 0.9142857142857143 False False False 0 False 0 6175.2 203.3 72.0 15.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 6 10 LYYSYGLLHIYGSGG LYYSYGLLHTYGSGG NNalign 223.0 300.9 1.349 NNalign 16.0 19.0 120 0.233 NA NA NA NA NA NA 223.0 300.9 1.349 16.0 19.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.2857142857142857 0.9714285714285714 False False False 0 False 0 300.9 223.0 19.0 16.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 5 11 WLYYSYGLLHIYGSG WLYYSYGLLHTYGSG NNalign 223.2 298.7 1.338 NNalign 16.0 19.0 120 0.233 NA NA NA NA NA NA 223.2 298.7 1.338 16.0 19.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.3142857142857142 0.9714285714285714 False False False 0 False 0 298.7 223.2 19.0 16.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 14 2 KHGGVSLSKIERSTD KPGGVSLSKIERSTD NNalign 243.8 292.1 1.198 NNalign 17.0 19.0 140 0.179 NA NA NA NA NA NA 243.8 292.1 1.198 17.0 19.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -1.7714285714285716 0.9428571428571428 False False False 0 False 0 292.1 243.8 19.0 17.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 7 9 YYSYGLLHIYGSGGY YYSYGLLHTYGSGGY NNalign 260.8 363.6 1.394 NNalign 17.0 21.0 120 0.233 NA NA NA NA NA NA 260.8 363.6 1.394 17.0 21.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.014285714285714266 0.9714285714285714 False False False 0 False 0 363.6 260.8 21.0 17.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 4 12 QWLYYSYGLLHIYGS QWLYYSYGLLHTYGS NNalign 263.2 335.9 1.276 NNalign 17.0 20.0 120 0.233 NA NA NA NA NA NA 263.2 335.9 1.276 17.0 20.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.914285714285714 0.9714285714285714 True False False 0 False 0 335.9 263.2 20.0 17.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 13 3 GKHGGVSLSKIERST GKPGGVSLSKIERST NNalign 282.5 349.6 1.238 NNalign 18.0 20.0 140 0.179 NA NA NA NA NA NA 282.5 349.6 1.238 18.0 20.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -1.3857142857142857 0.9428571428571428 False False False 0 False 0 349.6 282.5 20.0 18.0 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 3 13 RDTRVSLFGALVRSR RDTRVSLFGALVHSR NNalign 344.6 902.4 2.619 NNalign 20.0 33.0 210 0.686 NA NA NA NA NA NA 344.6 902.4 2.619 20.0 33.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.05714285714285732 2.1714285714285713 False False False 0 False 0 902.4 344.6 33.0 20.0 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 5 11 VPALGWEFLAFTRLT VPALGWEFLASTRLT NNalign 350.5 392.1 1.119 NNalign 20.0 22.0 171 0.959 NA NA NA NA NA NA 350.5 392.1 1.119 20.0 22.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.8999999999999997 1.4000000000000001 False False False 0 False 0 392.1 350.5 22.0 20.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 10 1, 2, 3, 4, 5 LSRTLLLAAAGGSSL TLSRTLLAAAGGSSL NNalign 428.3 681.6 1.591 NNalign 23.0 29.0 76 0.158 NA NA NA NA NA NA 428.3 681.6 1.591 23.0 29.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 0.7142857142857143 2.342857142857143 False False False 0 False 0 681.6 428.3 29.0 23.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 2 14 TALAIAGTLKFNPQT TALAIAGTLKFNPET NNalign 429.6 547.5 1.274 NNalign 23.0 26.0 136 0.25 NA NA NA NA NA NA 429.6 547.5 1.274 23.0 26.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 2.085714285714286 False False False 0 False 1 547.5 429.6 26.0 23.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 8 8 YSYGLLHIYGSGGYA YSYGLLHTYGSGGYA NNalign 432.7 607.8 1.405 NNalign 23.0 27.0 120 0.233 NA NA NA NA NA NA 432.7 607.8 1.405 23.0 27.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.39999999999999997 0.9714285714285714 False False False 0 False 0 607.8 432.7 27.0 23.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 11 1, 2, 3, 4 SRTLLLAAAGGSSLQ LSRTLLAAAGGSSLQ NNalign 451.2 546.2 1.211 NNalign 23.0 26.0 76 0.158 NA NA NA NA NA NA 451.2 546.2 1.211 23.0 26.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L -0.04285714285714289 2.342857142857143 False False False 0 False 0 546.2 451.2 26.0 23.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 3 13 TQWLYYSYGLLHIYG TQWLYYSYGLLHTYG NNalign 456.0 539.0 1.182 NNalign 24.0 26.0 120 0.233 NA NA NA NA NA NA 456.0 539.0 1.182 24.0 26.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9714285714285714 0.9714285714285714 False False False 0 False 0 539.0 456.0 26.0 24.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 2 14 YHVASVLCQRAKVEM YHVASVLCQRAKVAM NNalign 466.7 309.9 0.664 NNalign 24.0 19.0 113 0.044 NA NA NA NA NA NA 466.7 309.9 0.664 24.0 19.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -1.0714285714285712 1.7857142857142858 False False False 1 False 0 309.9 466.7 19.0 24.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 13 3 ELVYCLQKCNVPLFV ELAYCLQKCNVPLFV NNalign 488.8 855.7 1.751 NNalign 25.0 32.0 113 0.053 NA NA NA NA NA NA 488.8 855.7 1.751 25.0 32.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 1.7714285714285711 1.7714285714285711 True False False 2 False 0 855.7 488.8 32.0 25.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 3 13 ALAIAGTLKFNPQTD ALAIAGTLKFNPETD NNalign 489.0 655.4 1.34 NNalign 25.0 28.0 136 0.25 NA NA NA NA NA NA 489.0 655.4 1.34 25.0 28.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -1.9857142857142855 2.085714285714286 False False False 0 False 1 655.4 489.0 28.0 25.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 9 1, 2, 3, 4, 5, 6 TLSRTLLLAAAGGSS ATLSRTLLAAAGGSS NNalign 504.9 791.7 1.568 NNalign 25.0 31.0 76 0.158 NA NA NA NA NA NA 504.9 791.7 1.568 25.0 31.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 0.42857142857142855 2.342857142857143 False False False 0 False 0 791.7 504.9 31.0 25.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 12 1, 2, 3 RTLLLAAAGGSSLQT SRTLLAAAGGSSLQT NNalign 519.6 690.3 1.329 NNalign 25.0 29.0 76 0.158 NA NA NA NA NA NA 519.6 690.3 1.329 25.0 29.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L -0.4000000000000001 2.342857142857143 False False False 0 False 0 690.3 519.6 29.0 25.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 4 12 LAIAGTLKFNPQTDY LAIAGTLKFNPETDY NNalign 520.4 729.8 1.402 NNalign 25.0 30.0 136 0.25 NA NA NA NA NA NA 520.4 729.8 1.402 25.0 30.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -1.6142857142857143 2.085714285714286 False False False 0 False 1 729.8 520.4 30.0 25.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 12 4 LELVYCLQKCNVPLF LELAYCLQKCNVPLF NNalign 530.7 724.9 1.366 NNalign 25.0 30.0 113 0.053 NA NA NA NA NA NA 530.7 724.9 1.366 25.0 30.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 0.6142857142857141 1.9000000000000001 False False False 2 False 0 724.9 530.7 30.0 25.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 1 15 VTALAIAGTLKFNPQ VTALAIAGTLKFNPE NNalign 535.3 654.2 1.222 NNalign 26.0 28.0 136 0.25 NA NA NA NA NA NA 535.3 654.2 1.222 26.0 28.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 2.457142857142857 False False False 0 False 1 654.2 535.3 28.0 26.0 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 14 2 AFTRLTSELNFLLQE ASTRLTSELNFLLQE NNalign 558.2 5108.7 9.152 NNalign 26.0 68.0 171 0.959 NA NA NA NA NA NA 558.2 5108.7 9.152 26.0 68.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.5285714285714285 0.9142857142857143 False False False 0 False 0 5108.7 558.2 68.0 26.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 13 3 MDYLSDRCKILQVFD MDCLSDRCKILQVFD NNalign 586.5 2679.7 4.569 NNalign 27.0 53.0 92 0.043 NA NA NA NA NA NA 586.5 2679.7 4.569 27.0 53.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y 0.6285714285714287 1.4857142857142858 False False False 1 False 0 2679.7 586.5 53.0 27.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 8 9, 12, 14 ATLSRTLLLAAAGGS ATLSRTLLAAAGGSS NNalign 603.4 791.7 1.312 NNalign 27.0 31.0 76 0.158 NA NA NA NA NA NA 603.4 791.7 1.312 27.0 31.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0857142857142856 2.342857142857143 False False False 0 False 0 791.7 603.4 31.0 27.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 14 2 LVYCLQKCNVPLFVQ LAYCLQKCNVPLFVQ NNalign 615.9 829.4 1.347 NNalign 27.0 32.0 113 0.053 NA NA NA NA NA NA 615.9 829.4 1.347 27.0 32.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 0.914285714285714 1.7714285714285711 False False False 2 False 0 829.4 615.9 32.0 27.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 6 11, 14 NSATLSRTLLLAAAG NSATLSRTLLAAAGG NNalign 628.2 645.8 1.028 NNalign 28.0 28.0 76 0.158 NA NA NA NA NA NA 628.2 645.8 1.028 28.0 28.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.342857142857143 2.342857142857143 False False False 0 True 0 645.8 628.2 28.0 28.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 12 4 DMDYLSDRCKILQVF DMDCLSDRCKILQVF NNalign 641.6 2951.7 4.601 NNalign 28.0 56.0 92 0.043 NA NA NA NA NA NA 641.6 2951.7 4.601 28.0 56.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y 1.4857142857142858 1.4857142857142858 False False False 1 False 0 2951.7 641.6 56.0 28.0 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 15 1 RSRTYDMDVRLGLPP HSRTYDMDVRLGLPP NNalign 648.9 716.6 1.104 NNalign 28.0 30.0 210 0.686 NA NA NA NA NA NA 648.9 716.6 1.104 28.0 30.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R 0.5285714285714287 0.7571428571428571 False False True 0 False 0 716.6 648.9 30.0 28.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 11 5 PLELVYCLQKCNVPL PLELAYCLQKCNVPL NNalign 670.0 880.2 1.314 NNalign 29.0 33.0 113 0.053 NA NA NA NA NA NA 670.0 880.2 1.314 29.0 33.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V -0.28571428571428586 1.9000000000000001 False False False 2 False 0 880.2 670.0 33.0 29.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 7 10, 13, 15 SATLSRTLLLAAAGG SATLSRTLLAAAGGS NNalign 680.7 752.4 1.105 NNalign 29.0 30.0 76 0.158 NA NA NA NA NA NA 680.7 752.4 1.105 29.0 30.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.742857142857143 2.342857142857143 False False False 0 False 0 752.4 680.7 30.0 29.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 12 4 IGKHGGVSLSKIERS IGKPGGVSLSKIERS NNalign 699.8 924.5 1.321 NNalign 29.0 34.0 140 0.179 NA NA NA NA NA NA 699.8 924.5 1.321 29.0 34.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -0.7428571428571429 0.9428571428571428 False False False 0 False 0 924.5 699.8 34.0 29.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 3 13 HVASVLCQRAKVEMS HVASVLCQRAKVAMS NNalign 770.7 370.4 0.481 NNalign 31.0 21.0 113 0.044 NA NA NA NA NA NA 770.7 370.4 0.481 31.0 21.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -0.6857142857142857 1.7857142857142858 False False False 1 False 0 370.4 770.7 21.0 31.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 10 6 RPLELVYCLQKCNVP RPLELAYCLQKCNVP NNalign 777.8 943.7 1.213 NNalign 31.0 34.0 113 0.053 NA NA NA NA NA NA 777.8 943.7 1.213 31.0 34.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V -0.28571428571428564 1.9000000000000001 False False True 2 False 0 943.7 777.8 34.0 31.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 5 12, 15 VNSATLSRTLLLAAA VNSATLSRTLLAAAG NNalign 790.7 681.6 0.862 NNalign 31.0 29.0 76 0.158 NA NA NA NA NA NA 790.7 681.6 0.862 31.0 29.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 2.3000000000000003 2.3000000000000003 False False False 0 False 0 681.6 790.7 29.0 31.0 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 14 2 VRSRTYDMDVRLGLP VHSRTYDMDVRLGLP NNalign 794.1 879.5 1.108 NNalign 31.0 33.0 210 0.686 NA NA NA NA NA NA 794.1 879.5 1.108 31.0 33.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R 0.2571428571428571 0.7571428571428571 False False True 0 False 0 879.5 794.1 33.0 31.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 9 7 SYGLLHIYGSGGYAL SYGLLHTYGSGGYAL NNalign 796.9 1177.2 1.477 NNalign 31.0 38.0 120 0.233 NA NA NA NA NA NA 796.9 1177.2 1.477 31.0 38.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.32857142857142857 0.9714285714285714 False False False 0 False 0 1177.2 796.9 38.0 31.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 2 14 GTQWLYYSYGLLHIY GTQWLYYSYGLLHTY NNalign 807.3 862.8 1.069 NNalign 32.0 33.0 120 0.233 NA NA NA NA NA NA 807.3 862.8 1.069 32.0 33.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.8428571428571427 0.9142857142857143 False False False 0 False 0 862.8 807.3 33.0 32.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 5 11 TSAKTTVVVTTQKRN TSAKTTVVVTAQKRN NNalign 816.3 601.3 0.737 NNalign 32.0 27.0 96 0.042 NA NA NA NA NA NA 816.3 601.3 0.737 32.0 27.0 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -1.8 1.4000000000000001 False False False 0 False 0 601.3 816.3 27.0 32.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 14 2 DYLSDRCKILQVFDD DCLSDRCKILQVFDD NNalign 859.6 2861.0 3.328 NNalign 33.0 55.0 92 0.043 NA NA NA NA NA NA 859.6 2861.0 3.328 33.0 55.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y 0.6857142857142858 1.4857142857142858 False False False 1 False 0 2861.0 859.6 55.0 33.0 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 1 15 AIMYVPALGWEFLAF AIMYVPALGWEFLAS NNalign 898.3 870.2 0.969 NNalign 33.0 33.0 171 0.959 NA NA NA NA NA NA 898.3 870.2 0.969 33.0 33.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.9142857142857143 1.9000000000000001 False False False 0 False 0 870.2 898.3 33.0 33.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 11 5 DDMDYLSDRCKILQV DDMDCLSDRCKILQV NNalign 900.7 4408.6 4.895 NNalign 33.0 65.0 92 0.043 NA NA NA NA NA NA 900.7 4408.6 4.895 33.0 65.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y 0.4428571428571428 0.4428571428571428 False False False 1 False 0 4408.6 900.7 65.0 33.0 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 13 3 LVRSRTYDMDVRLGL LVHSRTYDMDVRLGL NNalign 931.9 1008.4 1.082 NNalign 34.0 35.0 210 0.686 NA NA NA NA NA NA 931.9 1008.4 1.082 34.0 35.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R 0.7571428571428571 0.7571428571428571 False False False 0 False 0 1008.4 931.9 35.0 34.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 4 12 VASVLCQRAKVEMSH VASVLCQRAKVAMSH NNalign 956.2 380.8 0.398 NNalign 34.0 21.0 113 0.044 NA NA NA NA NA NA 956.2 380.8 0.398 34.0 21.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -0.5 1.7428571428571427 False False False 1 False 0 380.8 956.2 21.0 34.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 15 1 VYCLQKCNVPLFVQH AYCLQKCNVPLFVQH NNalign 971.8 1187.7 1.222 NNalign 34.0 38.0 113 0.053 NA NA NA NA NA NA 971.8 1187.7 1.222 34.0 38.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 0.957142857142857 1.7714285714285711 False False False 2 False 0 1187.7 971.8 38.0 34.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 5 11 AIAGTLKFNPQTDYL AIAGTLKFNPETDYL NNalign 1021.3 1637.6 1.603 NNalign 35.0 44.0 136 0.25 NA NA NA NA NA NA 1021.3 1637.6 1.603 35.0 44.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -1.4714285714285715 1.1285714285714286 False False False 0 False 1 1637.6 1021.3 44.0 35.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 9 7 VRPLELVYCLQKCNV VRPLELAYCLQKCNV NNalign 1067.3 1236.9 1.159 NNalign 36.0 39.0 113 0.053 NA NA NA NA NA NA 1067.3 1236.9 1.159 36.0 39.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 0.3 1.9000000000000001 False False False 2 False 0 1236.9 1067.3 39.0 36.0 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 2 14 ERDTRVSLFGALVRS ERDTRVSLFGALVHS NNalign 1121.1 2361.1 2.106 NNalign 37.0 51.0 210 0.686 NA NA NA NA NA NA 1121.1 2361.1 2.106 37.0 51.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R 0.9857142857142857 2.1714285714285713 True False False 0 False 0 2361.1 1121.1 51.0 37.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 4 12 YVQWYQQRPGSAPTT YVQWYQQRPGSSPTT NNalign 1129.7 1129.4 1.0 NNalign 37.0 37.0 7 0.571 NA NA NA NA NA NA 1129.7 1129.4 1.0 37.0 37.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5714285714285714 -0.5714285714285714 False False False 0 False 0 1129.4 1129.7 37.0 37.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 4 13 SVNSATLSRTLLLAA SVNSATLSRTLLAAA NNalign 1132.3 818.6 0.723 NNalign 37.0 32.0 76 0.158 NA NA NA NA NA NA 1132.3 818.6 0.723 37.0 32.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.4 1.4 False False False 0 False 0 818.6 1132.3 32.0 37.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 13 1, 2, 4, 5 LPLLPLLLLLGASGG PLLPLLLLLLGASGG NNalign 1135.5 2570.9 2.264 NNalign 37.0 53.0 101 0.891 NA NA NA NA NA NA 1135.5 2570.9 2.264 37.0 53.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.057142857142857 3.028571428571429 False False False 0 False 0 2570.9 1135.5 53.0 37.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 14 1, 3, 4 PLLPLLLLLGASGGG LLPLLLLLLGASGGG NNalign 1142.5 2324.5 2.035 NNalign 37.0 51.0 101 0.891 NA NA NA NA NA NA 1142.5 2324.5 2.035 37.0 51.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 0.4571428571428572 3.028571428571429 False False False 0 False 0 2324.5 1142.5 51.0 37.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 5 11 ASVLCQRAKVEMSHF ASVLCQRAKVAMSHF NNalign 1155.7 353.0 0.305 NNalign 38.0 20.0 113 0.044 NA NA NA NA NA NA 1155.7 353.0 0.305 38.0 20.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -0.35714285714285715 0.5 False False False 1 False 0 353.0 1155.7 20.0 38.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 3 13 NYVQWYQQRPGSAPT NYVQWYQQRPGSSPT NNalign 1181.6 1181.8 1.0 NNalign 38.0 38.0 7 0.571 NA NA NA NA NA NA 1181.6 1181.8 1.0 38.0 38.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.1142857142857143 -1.1142857142857143 False False False 0 True 0 1181.8 1181.6 38.0 38.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 10 6 CDDMDYLSDRCKILQ CDDMDCLSDRCKILQ NNalign 1309.1 6352.5 4.853 NNalign 40.0 73.0 92 0.043 NA NA NA NA NA NA 1309.1 6352.5 4.853 40.0 73.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.6571428571428573 -0.27142857142857146 True False False 2 False 0 6352.5 1309.1 73.0 40.0 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 12 4 ALVRSRTYDMDVRLG ALVHSRTYDMDVRLG NNalign 1312.6 1644.9 1.253 NNalign 40.0 44.0 210 0.686 NA NA NA NA NA NA 1312.6 1644.9 1.253 40.0 44.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.28571428571428564 -0.09999999999999987 False False False 0 False 0 1644.9 1312.6 44.0 40.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 16 1, 2 LPLLLLLGASGGGGG PLLLLLLGASGGGGG NNalign 1335.8 1663.7 1.245 NNalign 40.0 44.0 101 0.891 NA NA NA NA NA NA 1335.8 1663.7 1.245 40.0 44.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP -0.14285714285714285 3.028571428571429 False False False 0 False 0 1663.7 1335.8 44.0 40.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 15 2, 3 LLPLLLLLGASGGGG LPLLLLLLGASGGGG NNalign 1340.1 1891.9 1.412 NNalign 40.0 46.0 101 0.891 NA NA NA NA NA NA 1340.1 1891.9 1.412 40.0 46.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP -0.14285714285714288 3.028571428571429 False False False 0 False 0 1891.9 1340.1 46.0 40.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 1 15 QGTQWLYYSYGLLHI QGTQWLYYSYGLLHT NNalign 1401.7 1410.6 1.006 NNalign 41.0 41.0 120 0.233 NA NA NA NA NA NA 1401.7 1410.6 1.006 41.0 41.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.9142857142857143 0.9142857142857143 True False False 0 False 0 1410.6 1401.7 41.0 41.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 17 1 PLLLLLGASGGGGGA LLLLLLGASGGGGGA NNalign 1401.9 1838.7 1.312 NNalign 41.0 46.0 101 0.891 NA NA NA NA NA NA 1401.9 1838.7 1.312 41.0 46.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP -0.14285714285714282 2.9142857142857146 False False False 0 False 0 1838.7 1401.9 46.0 41.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 2 14 SNYVQWYQQRPGSAP SNYVQWYQQRPGSSP NNalign 1445.3 1445.8 1.0 NNalign 41.0 41.0 7 0.571 NA NA NA NA NA NA 1445.3 1445.8 1.0 41.0 41.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.5142857142857142 -1.0142857142857142 False False True 0 False 0 1445.8 1445.3 41.0 41.0 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 2 14 IMYVPALGWEFLAFT IMYVPALGWEFLAST NNalign 1472.3 1368.2 0.929 NNalign 42.0 41.0 171 0.959 NA NA NA NA NA NA 1472.3 1368.2 0.929 42.0 41.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.8714285714285712 1.9000000000000001 False False False 0 False 0 1368.2 1472.3 41.0 42.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 12 1, 2, 3, 5, 6 LLPLLPLLLLLGASG PPLLPLLLLLLGASG NNalign 1479.2 2850.1 1.927 NNalign 42.0 55.0 101 0.891 NA NA NA NA NA NA 1479.2 2850.1 1.927 42.0 55.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.6571428571428568 3.028571428571429 False False False 0 False 0 2850.1 1479.2 55.0 42.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 13 1, 2 TLLLAAAGGSSLQTQ RTLLAAAGGSSLQTQ NNalign 1481.1 942.5 0.636 NNalign 42.0 34.0 76 0.158 NA NA NA NA NA NA 1481.1 942.5 0.636 42.0 34.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L -0.8428571428571429 2.342857142857143 False False False 0 False 0 942.5 1481.1 34.0 42.0 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 11 5 GALVRSRTYDMDVRL GALVHSRTYDMDVRL NNalign 1483.2 2044.5 1.378 NNalign 42.0 48.0 210 0.686 NA NA NA NA NA NA 1483.2 2044.5 1.378 42.0 48.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -0.4142857142857143 -0.05714285714285732 False False False 0 False 0 2044.5 1483.2 48.0 42.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 7 9 KAVRPLELVYCLQKC KAVRPLELAYCLQKC NNalign 1500.4 1228.1 0.819 NNalign 42.0 39.0 113 0.053 NA NA NA NA NA NA 1500.4 1228.1 0.819 42.0 39.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 0.6142857142857141 1.9000000000000001 False True False 2 False 0 1228.1 1500.4 39.0 42.0 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 1 15 FERDTRVSLFGALVR FERDTRVSLFGALVH NNalign 1558.0 2036.3 1.307 NNalign 43.0 48.0 210 0.686 NA NA NA NA NA NA 1558.0 2036.3 1.307 43.0 48.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R 1.6428571428571428 2.1714285714285713 False False False 0 False 0 2036.3 1558.0 48.0 43.0 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 4 12 YVPALGWEFLAFTRL YVPALGWEFLASTRL NNalign 1561.3 1391.0 0.891 NNalign 43.0 41.0 171 0.959 NA NA NA NA NA NA 1561.3 1391.0 0.891 43.0 41.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 1.4000000000000001 1.4000000000000001 False False False 0 False 0 1391.0 1561.3 41.0 43.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 8 8 AVRPLELVYCLQKCN AVRPLELAYCLQKCN NNalign 1618.6 1535.1 0.948 NNalign 43.0 42.0 113 0.053 NA NA NA NA NA NA 1618.6 1535.1 0.948 43.0 42.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V -0.4857142857142857 1.9000000000000001 False False False 2 False 0 1535.1 1618.6 42.0 43.0 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 15 1 FTRLTSELNFLLQEI STRLTSELNFLLQEI NNalign 1628.4 4539.9 2.788 NNalign 44.0 65.0 171 0.959 NA NA NA NA NA NA 1628.4 4539.9 2.788 44.0 65.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.6285714285714284 0.9142857142857143 False False False 0 False 0 4539.9 1628.4 65.0 44.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 11 2, 3, 4, 6, 7 PLLPLLPLLLLLGAS PPPLLPLLLLLLGAS NNalign 1630.5 4478.7 2.747 NNalign 44.0 65.0 101 0.891 NA NA NA NA NA NA 1630.5 4478.7 2.747 44.0 65.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.2571428571428567 3.028571428571429 False False False 0 False 0 4478.7 1630.5 65.0 44.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 15 1 TQKRNSRRQLPSFLP AQKRNSRRQLPSFLP NNalign 1648.4 1678.9 1.019 NNalign 44.0 44.0 96 0.042 NA NA NA NA NA NA 1648.4 1678.9 1.019 44.0 44.0 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T 0.41428571428571415 0.41428571428571415 False False True 0 False 0 1678.9 1648.4 44.0 44.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 14 2 TTQKRNSRRQLPSFL TAQKRNSRRQLPSFL NNalign 1668.6 1740.6 1.043 NNalign 44.0 45.0 96 0.042 NA NA NA NA NA NA 1668.6 1740.6 1.043 44.0 45.0 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -1.2688263138573217e-16 -1.2688263138573217e-16 False False False 0 False 0 1740.6 1668.6 45.0 44.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 13 3 VTTQKRNSRRQLPSF VTAQKRNSRRQLPSF NNalign 1670.7 1688.4 1.011 NNalign 44.0 44.0 96 0.042 NA NA NA NA NA NA 1670.7 1688.4 1.011 44.0 44.0 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -1.1857142857142857 -1.1857142857142857 False False False 0 False 0 1688.4 1670.7 44.0 44.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 15 1 QTDYLTGTDGKKFRL ETDYLTGTDGKKFRL NNalign 1682.4 1841.9 1.095 NNalign 44.0 46.0 136 0.25 NA NA NA NA NA NA 1682.4 1841.9 1.095 44.0 46.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -1.3714285714285712 -0.45714285714285713 True False False 0 False 0 1841.9 1682.4 46.0 44.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 5 11 VQWYQQRPGSAPTTV VQWYQQRPGSSPTTV NNalign 1700.4 1717.9 1.01 NNalign 44.0 45.0 7 0.571 NA NA NA NA NA NA 1700.4 1717.9 1.01 44.0 45.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.2571428571428571 0.2571428571428571 False False False 0 False 0 1717.9 1700.4 45.0 44.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 6 10 QKAVRPLELVYCLQK QKAVRPLELAYCLQK NNalign 1732.3 1403.3 0.81 NNalign 45.0 41.0 113 0.053 NA NA NA NA NA NA 1732.3 1403.3 0.81 45.0 41.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 0.7999999999999999 1.9000000000000001 True False False 1 False 0 1403.3 1732.3 41.0 45.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 10 8, 12, 13, 14, 15 PPLLPLLPLLLLLGA PPLLPLLLLLLGASG NNalign 1732.6 2850.1 1.645 NNalign 45.0 55.0 101 0.891 NA NA NA NA NA NA 1732.6 2850.1 1.645 45.0 55.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.9142857142857146 3.028571428571429 False False False 0 False 0 2850.1 1732.6 55.0 45.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 1 15 ASLASLMVCELAGNL ASLASLMVCELAGNP NNalign 1739.7 1772.2 1.019 NNalign 45.0 45.0 303 0.135 NA NA NA NA NA NA 1739.7 1772.2 1.019 45.0 45.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6428571428571427 2.457142857142857 False False False 1 False 0 1772.2 1739.7 45.0 45.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 6 10 SVLCQRAKVEMSHFE SVLCQRAKVAMSHFE NNalign 1745.0 427.6 0.245 NNalign 45.0 23.0 113 0.044 NA NA NA NA NA NA 1745.0 427.6 0.245 45.0 23.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -0.3000000000000001 0.4999999999999999 False False False 1 False 0 427.6 1745.0 23.0 45.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 15 1 YLSDRCKILQVFDDF CLSDRCKILQVFDDF NNalign 1843.1 3013.5 1.635 NNalign 46.0 56.0 92 0.043 NA NA NA NA NA NA 1843.1 3013.5 1.635 46.0 56.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y 0.4428571428571428 1.4857142857142858 False False False 1 False 0 3013.5 1843.1 56.0 46.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 3 14 TSVNSATLSRTLLLA TSVNSATLSRTLLAA NNalign 1904.8 1385.3 0.727 NNalign 47.0 41.0 76 0.158 NA NA NA NA NA NA 1904.8 1385.3 0.727 47.0 41.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.0285714285714285 1.3142857142857143 False False False 0 False 0 1385.3 1904.8 41.0 47.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 10 6 YGLLHIYGSGGYALY YGLLHTYGSGGYALY NNalign 1932.4 2501.6 1.295 NNalign 47.0 52.0 120 0.233 NA NA NA NA NA NA 1932.4 2501.6 1.295 47.0 52.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.1999999999999999 0.9714285714285714 False False False 0 False 0 2501.6 1932.4 52.0 47.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 1 15 ASNYVQWYQQRPGSA ASNYVQWYQQRPGSS NNalign 2014.7 2086.5 1.036 NNalign 48.0 48.0 7 0.571 NA NA NA NA NA NA 2014.7 2086.5 1.036 48.0 48.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -1.7857142857142858 -0.5714285714285714 False False False 0 False 0 2086.5 2014.7 48.0 48.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 14 2 PQTDYLTGTDGKKFR PETDYLTGTDGKKFR NNalign 2274.4 2484.3 1.092 NNalign 50.0 52.0 136 0.25 NA NA NA NA NA NA 2274.4 2484.3 1.092 50.0 52.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -2.0142857142857147 -0.45714285714285713 False False False 0 False 0 2484.3 2274.4 52.0 50.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 9 9, 13, 14, 15 PPPLLPLLPLLLLLG PPPLLPLLLLLLGAS NNalign 2319.2 4478.7 1.931 NNalign 51.0 65.0 101 0.891 NA NA NA NA NA NA 2319.2 4478.7 1.931 51.0 65.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.4285714285714293 3.028571428571429 False False False 0 False 0 4478.7 2319.2 65.0 51.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 2 14 SLASLMVCELAGNLF SLASLMVCELAGNPF NNalign 2393.3 2560.5 1.07 NNalign 51.0 52.0 303 0.135 NA NA NA NA NA NA 2393.3 2560.5 1.07 51.0 52.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 2.457142857142857 False False False 1 False 0 2560.5 2393.3 52.0 51.0 -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 3 13 MYVPALGWEFLAFTR MYVPALGWEFLASTR NNalign 2400.8 2683.0 1.118 NNalign 51.0 53.0 171 0.959 NA NA NA NA NA NA 2400.8 2683.0 1.118 51.0 53.0 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F 0.35714285714285704 1.2 False False False 0 False 0 2683.0 2400.8 53.0 51.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 9 7 PCDDMDYLSDRCKIL PCDDMDCLSDRCKIL NNalign 2423.7 10016.6 4.133 NNalign 51.0 82.0 92 0.043 NA NA NA NA NA NA 2423.7 10016.6 4.133 51.0 82.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857163 -0.27142857142857146 False False False 2 False 0 10016.6 2423.7 82.0 51.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 11 5 LIGKHGGVSLSKIER LIGKPGGVSLSKIER NNalign 2700.9 3993.4 1.479 NNalign 54.0 62.0 140 0.179 NA NA NA NA NA NA 2700.9 3993.4 1.479 54.0 62.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -0.7428571428571428 0.9428571428571428 False False False 0 False 0 3993.4 2700.9 62.0 54.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 6 10 IAGTLKFNPQTDYLT IAGTLKFNPETDYLT NNalign 2755.1 4802.9 1.743 NNalign 54.0 67.0 136 0.25 NA NA NA NA NA NA 2755.1 4802.9 1.743 54.0 67.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -1.0714285714285716 1.1285714285714286 False False False 0 False 1 4802.9 2755.1 67.0 54.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 6 10 QWYQQRPGSAPTTVI QWYQQRPGSSPTTVI NNalign 2824.5 2791.4 0.988 NNalign 55.0 54.0 7 0.571 NA NA NA NA NA NA 2824.5 2791.4 0.988 55.0 54.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.9571428571428572 0.9571428571428572 True False False 0 False 0 2791.4 2824.5 54.0 55.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 7 9 HHEDLIGKHGGVSLS HHEDLIGKPGGVSLS NNalign 2876.0 6490.7 2.257 NNalign 55.0 73.0 140 0.179 NA NA NA NA NA NA 2876.0 6490.7 2.257 55.0 73.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H 0.3428571428571429 0.3428571428571429 False False False 0 False 0 6490.7 2876.0 73.0 55.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 6 10 LHHEDLIGKHGGVSL LHHEDLIGKPGGVSL NNalign 2926.7 6745.5 2.305 NNalign 55.0 74.0 140 0.179 NA NA NA NA NA NA 2926.7 6745.5 2.305 55.0 74.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -0.10000000000000002 0.05714285714285713 False False False 0 False 0 6745.5 2926.7 74.0 55.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 5 11 VLHHEDLIGKHGGVS VLHHEDLIGKPGGVS NNalign 2931.7 6517.2 2.223 NNalign 55.0 73.0 140 0.179 NA NA NA NA NA NA 2931.7 6517.2 2.223 55.0 73.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -0.7000000000000001 0.05714285714285713 False False False 0 False 0 6517.2 2931.7 73.0 55.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 14 1 LLLAAAGGSSLQTQR TLLAAAGGSSLQTQR NNalign 2951.2 2825.3 0.957 NNalign 56.0 55.0 76 0.158 NA NA NA NA NA NA 2951.2 2825.3 0.957 56.0 55.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L -1.4285714285714286 2.342857142857143 False False False 0 False 0 2825.3 2951.2 55.0 56.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 5 11 PGKTVTISCTGSSGS PGKTVTISCTRSSGS NNalign 2994.6 726.8 0.243 NNalign 56.0 30.0 5 1.0 NA NA NA NA NA NA 2994.6 726.8 0.243 56.0 30.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.20000000000000004 1.2285714285714284 False False False 1 False 0 726.8 2994.6 30.0 56.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 4 12 AVLHHEDLIGKHGGV AVLHHEDLIGKPGGV NNalign 3004.1 5887.2 1.96 NNalign 56.0 71.0 140 0.179 NA NA NA NA NA NA 3004.1 5887.2 1.96 56.0 71.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H 0.05714285714285713 0.05714285714285713 False False False 0 False 0 5887.2 3004.1 71.0 56.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 3 13 LASLMVCELAGNLFN LASLMVCELAGNPFN NNalign 3016.7 3396.4 1.126 NNalign 56.0 59.0 303 0.135 NA NA NA NA NA NA 3016.7 3396.4 1.126 56.0 59.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6857142857142856 2.457142857142857 False False False 1 False 0 3396.4 3016.7 59.0 56.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 5 11 RQKAVRPLELVYCLQ RQKAVRPLELAYCLQ NNalign 3051.1 2597.7 0.851 NNalign 56.0 53.0 113 0.053 NA NA NA NA NA NA 3051.1 2597.7 0.851 56.0 53.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 0.8571428571428571 1.9000000000000001 False False False 1 False 0 2597.7 3051.1 53.0 56.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 8 8 GTLKFNPQTDYLTGT GTLKFNPETDYLTGT NNalign 3078.5 6160.4 2.001 NNalign 56.0 72.0 136 0.25 NA NA NA NA NA NA 3078.5 6160.4 2.001 56.0 72.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -0.5 -0.5 False False False 0 False 1 6160.4 3078.5 72.0 56.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 8 8 HEDLIGKHGGVSLSK HEDLIGKPGGVSLSK NNalign 3126.5 5535.6 1.771 NNalign 57.0 70.0 140 0.179 NA NA NA NA NA NA 3126.5 5535.6 1.771 57.0 70.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H 0.24285714285714294 0.3428571428571429 False False False 0 False 0 5535.6 3126.5 70.0 57.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 6 10 GKTVTISCTGSSGSI GKTVTISCTRSSGSI NNalign 3166.2 644.6 0.204 NNalign 57.0 28.0 5 1.0 NA NA NA NA NA NA 3166.2 644.6 0.204 57.0 28.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.08571428571428566 1.2285714285714284 False False False 1 False 0 644.6 3166.2 28.0 57.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 4 12 LTSAKTTVVVTTQKR LTSAKTTVVVTAQKR NNalign 3176.6 2433.3 0.766 NNalign 57.0 51.0 96 0.042 NA NA NA NA NA NA 3176.6 2433.3 0.766 57.0 51.0 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -0.7000000000000001 1.4000000000000001 False False False 0 False 0 2433.3 3176.6 51.0 57.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 7 9 VLCQRAKVEMSHFEP VLCQRAKVAMSHFEP NNalign 3285.8 607.7 0.185 NNalign 58.0 27.0 113 0.044 NA NA NA NA NA NA 3285.8 607.7 0.185 58.0 27.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 0.0571428571428572 False False True 1 False 0 607.7 3285.8 27.0 58.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 2 15 QTSVNSATLSRTLLL QTSVNSATLSRTLLA NNalign 3310.0 2692.0 0.813 NNalign 58.0 53.0 76 0.158 NA NA NA NA NA NA 3310.0 2692.0 0.813 58.0 53.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 1.3142857142857143 1.3142857142857143 True False False 0 False 0 2692.0 3310.0 53.0 58.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 8 10, 14, 15 PPPPLLPLLPLLLLL PPPPLLPLLLLLLGA NNalign 3392.9 6133.2 1.808 NNalign 59.0 72.0 101 0.891 NA NA NA NA NA NA 3392.9 6133.2 1.808 59.0 72.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 6133.2 3392.9 72.0 59.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 4 12 TSLLHTVSPEPARPP TSLLHTVSPEPPRPP NNalign 3433.3 6964.2 2.028 NNalign 59.0 75.0 245 0.486 NA NA NA NA NA NA 3433.3 6964.2 2.028 59.0 75.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -1.7999999999999996 0.9142857142857143 False False True 0 False 0 6964.2 3433.3 75.0 59.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 8 8 LCQRAKVEMSHFEPN LCQRAKVAMSHFEPN NNalign 3509.3 715.6 0.204 NNalign 59.0 30.0 113 0.044 NA NA NA NA NA NA 3509.3 715.6 0.204 59.0 30.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -1.1285714285714286 0.0571428571428572 False False False 1 False 0 715.6 3509.3 30.0 59.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 2 14 SATSLLHTVSPEPAR SATSLLHTVSPEPPR NNalign 3567.7 5326.2 1.493 NNalign 60.0 69.0 245 0.486 NA NA NA NA NA NA 3567.7 5326.2 1.493 60.0 69.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -0.8571428571428571 0.9142857142857143 False False False 0 False 0 5326.2 3567.7 69.0 60.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 3 13 ATSLLHTVSPEPARP ATSLLHTVSPEPPRP NNalign 3586.8 6378.8 1.778 NNalign 60.0 73.0 245 0.486 NA NA NA NA NA NA 3586.8 6378.8 1.778 60.0 73.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -1.6857142857142855 0.9142857142857143 False False True 0 False 0 6378.8 3586.8 73.0 60.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 4 12 SPGKTVTISCTGSSG SPGKTVTISCTRSSG NNalign 3650.3 1181.5 0.324 NNalign 60.0 38.0 5 1.0 NA NA NA NA NA NA 3650.3 1181.5 0.324 60.0 38.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.19999999999999998 1.2285714285714284 False False False 1 False 0 1181.5 3650.3 38.0 60.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 1 15 SQALTSAKTTVVVTT SQALTSAKTTVVVTA NNalign 3718.7 3618.5 0.973 NNalign 61.0 60.0 96 0.042 NA NA NA NA NA NA 3718.7 3618.5 0.973 61.0 60.0 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.4000000000000001 1.4000000000000001 False False False 0 False 0 3618.5 3718.7 60.0 61.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 4 12 SRQKAVRPLELVYCL SRQKAVRPLELAYCL NNalign 3744.7 3227.5 0.862 NNalign 61.0 57.0 113 0.053 NA NA NA NA NA NA 3744.7 3227.5 0.862 61.0 57.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 1.9000000000000001 1.9000000000000001 False False False 1 False 0 3227.5 3744.7 57.0 61.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 4 12 ASLMVCELAGNLFNC ASLMVCELAGNPFNC NNalign 3866.4 4633.1 1.198 NNalign 62.0 66.0 303 0.135 NA NA NA NA NA NA 3866.4 4633.1 1.198 62.0 66.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.5 2.0714285714285716 False True False 2 False 0 4633.1 3866.4 66.0 62.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 1 15 SSATSLLHTVSPEPA SSATSLLHTVSPEPP NNalign 3904.2 4685.2 1.2 NNalign 62.0 66.0 245 0.486 NA NA NA NA NA NA 3904.2 4685.2 1.2 62.0 66.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -0.31428571428571433 0.9142857142857143 False False False 0 False 0 4685.2 3904.2 66.0 62.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 7 9 AGTLKFNPQTDYLTG AGTLKFNPETDYLTG NNalign 3907.1 7609.1 1.948 NNalign 62.0 77.0 136 0.25 NA NA NA NA NA NA 3907.1 7609.1 1.948 62.0 77.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9000000000000001 -0.0142857142857143 False False False 0 False 1 7609.1 3907.1 77.0 62.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 9 7 EDLIGKHGGVSLSKI EDLIGKPGGVSLSKI NNalign 3959.3 6364.1 1.607 NNalign 62.0 73.0 140 0.179 NA NA NA NA NA NA 3959.3 6364.1 1.607 62.0 73.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H 0.9428571428571428 0.9428571428571428 True False False 0 False 0 6364.1 3959.3 73.0 62.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 5 11 SLLHTVSPEPARPPQ SLLHTVSPEPPRPPQ NNalign 4019.3 8706.6 2.166 NNalign 63.0 79.0 245 0.486 NA NA NA NA NA NA 4019.3 8706.6 2.166 63.0 79.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 0.9 False False False 0 False 0 8706.6 4019.3 79.0 63.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 11 5 GLLHIYGSGGYALYF GLLHTYGSGGYALYF NNalign 4089.2 5321.8 1.301 NNalign 63.0 69.0 120 0.233 NA NA NA NA NA NA 4089.2 5321.8 1.301 63.0 69.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.7142857142857143 0.9714285714285714 False False False 0 False 0 5321.8 4089.2 69.0 63.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 7 11, 15 LPPPPLLPLLPLLLL LPPPPLLPLLLLLLG NNalign 4241.4 8513.0 2.007 NNalign 64.0 79.0 101 0.891 NA NA NA NA NA NA 4241.4 8513.0 2.007 64.0 79.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 3.028571428571429 3.028571428571429 False False False 0 False 0 8513.0 4241.4 79.0 64.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 3 13 DAVLHHEDLIGKHGG DAVLHHEDLIGKPGG NNalign 4245.8 7723.3 1.819 NNalign 64.0 77.0 140 0.179 NA NA NA NA NA NA 4245.8 7723.3 1.819 64.0 77.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -3.172065784643304e-17 -3.172065784643304e-17 False False False 0 False 0 7723.3 4245.8 77.0 64.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 10 6 DLIGKHGGVSLSKIE DLIGKPGGVSLSKIE NNalign 4604.0 7523.6 1.634 NNalign 66.0 76.0 140 0.179 NA NA NA NA NA NA 4604.0 7523.6 1.634 66.0 76.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H 0.5 0.9428571428571428 False False False 0 False 0 7523.6 4604.0 76.0 66.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 14 2 KTQEVKVKEPPKKAE KPQEVKVKEPPKKAE NNalign 4730.4 4999.5 1.057 NNalign 66.0 68.0 185 0.038 NA NA NA NA NA NA 4730.4 4999.5 1.057 66.0 68.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.314285714285714 -0.8714285714285713 False False False 0 False 0 4999.5 4730.4 68.0 66.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 2 14 QALTSAKTTVVVTTQ QALTSAKTTVVVTAQ NNalign 4742.1 4411.7 0.93 NNalign 66.0 65.0 96 0.042 NA NA NA NA NA NA 4742.1 4411.7 0.93 66.0 65.0 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T 1.0000000000000002 1.4000000000000001 True False False 0 False 0 4411.7 4742.1 65.0 66.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 13 3 NPQTDYLTGTDGKKF NPETDYLTGTDGKKF NNalign 4823.6 5274.8 1.094 NNalign 67.0 69.0 136 0.25 NA NA NA NA NA NA 4823.6 5274.8 1.094 67.0 69.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -1.4285714285714286 -0.45714285714285713 False False False 0 True 1 5274.8 4823.6 69.0 67.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 3 13 DSRQKAVRPLELVYC DSRQKAVRPLELAYC NNalign 4890.8 4018.6 0.822 NNalign 67.0 63.0 113 0.053 NA NA NA NA NA NA 4890.8 4018.6 0.822 67.0 63.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 1.1285714285714286 1.1285714285714286 False True False 1 False 0 4018.6 4890.8 63.0 67.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 9 7 CQRAKVEMSHFEPNE CQRAKVAMSHFEPNE NNalign 4916.9 1069.1 0.217 NNalign 67.0 36.0 113 0.044 NA NA NA NA NA NA 4916.9 1069.1 0.217 67.0 36.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -1.9000000000000001 -0.3000000000000001 True False False 1 False 0 1069.1 4916.9 36.0 67.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 15 1 TQEVKVKEPPKKAEE PQEVKVKEPPKKAEE NNalign 5065.6 4986.9 0.984 NNalign 68.0 67.0 185 0.038 NA NA NA NA NA NA 5065.6 4986.9 0.984 68.0 67.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.314285714285714 -0.8714285714285713 False False False 0 False 0 4986.9 5065.6 67.0 68.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 7 9 KTVTISCTGSSGSIA KTVTISCTRSSGSIA NNalign 5077.0 781.0 0.154 NNalign 68.0 31.0 5 1.0 NA NA NA NA NA NA 5077.0 781.0 0.154 68.0 31.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.4428571428571428 1.2285714285714284 False False False 1 False 0 781.0 5077.0 31.0 68.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 3 13 ESPGKTVTISCTGSS ESPGKTVTISCTRSS NNalign 5125.8 2229.3 0.435 NNalign 68.0 50.0 5 1.0 NA NA NA NA NA NA 5125.8 2229.3 0.435 68.0 50.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5 1.2285714285714284 True False False 1 False 0 2229.3 5125.8 50.0 68.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 9 7 TLKFNPQTDYLTGTD TLKFNPETDYLTGTD NNalign 5183.2 8599.8 1.659 NNalign 68.0 79.0 136 0.25 NA NA NA NA NA NA 5183.2 8599.8 1.659 68.0 79.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -0.9 -0.5 False False False 0 False 1 8599.8 5183.2 79.0 68.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 10 6 QRAKVEMSHFEPNEY QRAKVAMSHFEPNEY NNalign 5403.7 1280.3 0.237 NNalign 69.0 39.0 113 0.044 NA NA NA NA NA NA 5403.7 1280.3 0.237 69.0 39.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -1.9714285714285715 -0.3000000000000001 True False False 0 False 0 1280.3 5403.7 39.0 69.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 12 4 LLHIYGSGGYALYFF LLHTYGSGGYALYFF NNalign 5510.2 7668.9 1.392 NNalign 70.0 77.0 120 0.233 NA NA NA NA NA NA 5510.2 7668.9 1.392 70.0 77.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 1.1714285714285713 1.1714285714285713 False False False 0 False 0 7668.9 5510.2 77.0 70.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 5 11 SLMVCELAGNLFNCE SLMVCELAGNPFNCE NNalign 5515.2 6648.1 1.205 NNalign 70.0 74.0 303 0.135 NA NA NA NA NA NA 5515.2 6648.1 1.205 70.0 74.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L -0.2571428571428572 2.0714285714285716 False False False 2 False 0 6648.1 5515.2 74.0 70.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 13 3 EKTQEVKVKEPPKKA EKPQEVKVKEPPKKA NNalign 5805.2 6349.4 1.094 NNalign 71.0 73.0 185 0.038 NA NA NA NA NA NA 5805.2 6349.4 1.094 71.0 73.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.371428571428571 -0.8714285714285713 True False False 0 False 0 6349.4 5805.2 73.0 71.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 15 1 GSSGSIASNYVQWYQ RSSGSIASNYVQWYQ NNalign 5892.7 5691.5 0.966 NNalign 71.0 70.0 5 1.0 NA NA NA NA NA NA 5892.7 5691.5 0.966 71.0 70.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G -1.4000000000000001 0.5857142857142857 False False False 0 False 0 5691.5 5892.7 70.0 71.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 8 8 QPCDDMDYLSDRCKI QPCDDMDCLSDRCKI NNalign 5895.8 15374.3 2.608 NNalign 71.0 90.0 92 0.043 NA NA NA NA NA NA 5895.8 15374.3 2.608 71.0 90.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.27142857142857146 -0.27142857142857146 True False False 2 False 0 15374.3 5895.8 90.0 71.0 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 3 13 ALTSAKTTVVVTTQK ALTSAKTTVVVTAQK NNalign 6253.0 5351.4 0.856 NNalign 72.0 69.0 96 0.042 NA NA NA NA NA NA 6253.0 5351.4 0.856 72.0 69.0 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T 0.5428571428571433 1.4000000000000001 False False False 0 False 0 5351.4 6253.0 69.0 72.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 2 14 SDAVLHHEDLIGKHG SDAVLHHEDLIGKPG NNalign 6314.8 8963.6 1.419 NNalign 73.0 80.0 140 0.179 NA NA NA NA NA NA 6314.8 8963.6 1.419 73.0 80.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -0.44285714285714295 -0.12857142857142861 False False False 0 False 0 8963.6 6314.8 80.0 73.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 11 5 RAKVEMSHFEPNEYI RAKVAMSHFEPNEYI NNalign 6379.4 2011.3 0.315 NNalign 73.0 48.0 113 0.044 NA NA NA NA NA NA 6379.4 2011.3 0.315 73.0 48.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -0.8714285714285717 -0.3000000000000001 False False False 0 False 0 2011.3 6379.4 48.0 73.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 8 8 GGSHVWTHSRDPEGS GGSHVWTRSRDPEGS NNalign 6419.7 1915.0 0.298 NNalign 73.0 47.0 56 0.071 NA NA NA NA NA NA 6419.7 1915.0 0.298 73.0 47.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -0.31428571428571433 False False False 0 False 0 1915.0 6419.7 47.0 73.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 10 6 LKFNPQTDYLTGTDG LKFNPETDYLTGTDG NNalign 6530.0 9851.3 1.509 NNalign 73.0 82.0 136 0.25 NA NA NA NA NA NA 6530.0 9851.3 1.509 73.0 82.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -0.45714285714285713 -0.45714285714285713 False False False 0 False 1 9851.3 6530.0 82.0 73.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 9 7 VQGIANQDAAQGIAK VQGIANEDAAQGIAK NNalign 6577.2 9312.4 1.416 NNalign 73.0 81.0 22 0.5 NA NA NA NA NA NA 6577.2 9312.4 1.416 73.0 81.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.3 0.35714285714285715 False False False 0 False 0 9312.4 6577.2 81.0 73.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 6 10 LLHTVSPEPARPPQQ LLHTVSPEPPRPPQQ NNalign 6588.1 14581.1 2.213 NNalign 73.0 89.0 245 0.486 NA NA NA NA NA NA 6588.1 14581.1 2.213 73.0 89.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 0.7857142857142857 False False False 0 False 0 14581.1 6588.1 89.0 73.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 6 12 PLPPPPLLPLLPLLL PLPPPPLLPLLLLLL NNalign 6722.5 11669.0 1.736 NNalign 74.0 85.0 101 0.891 NA NA NA NA NA NA 6722.5 11669.0 1.736 74.0 85.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 11669.0 6722.5 85.0 74.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 2 14 QDSRQKAVRPLELVY QDSRQKAVRPLELAY NNalign 6734.7 5180.2 0.769 NNalign 74.0 68.0 113 0.053 NA NA NA NA NA NA 6734.7 5180.2 0.769 74.0 68.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 0.1285714285714286 0.9142857142857144 True False False 0 False 0 5180.2 6734.7 68.0 74.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 7 9 SGGSHVWTHSRDPEG SGGSHVWTRSRDPEG NNalign 6816.3 2071.0 0.304 NNalign 74.0 48.0 56 0.071 NA NA NA NA NA NA 6816.3 2071.0 0.304 74.0 48.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.5 -0.31428571428571433 False False False 0 False 0 2071.0 6816.3 48.0 74.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 1 15 QGISKEDAVQGIANQ QGISKEDAVQGIANE NNalign 6852.9 7177.3 1.047 NNalign 74.0 75.0 22 0.5 NA NA NA NA NA NA 6852.9 7177.3 1.047 74.0 75.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.0571428571428572 0.7000000000000001 True False False 0 False 0 7177.3 6852.9 75.0 74.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 7 9 WYQQRPGSAPTTVIY WYQQRPGSSPTTVIY NNalign 6979.0 6878.6 0.986 NNalign 75.0 74.0 7 0.571 NA NA NA NA NA NA 6979.0 6878.6 0.986 75.0 74.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.8857142857142858 0.9571428571428572 False False False 0 False 0 6878.6 6979.0 74.0 75.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 10 6 QGIANQDAAQGIAKE QGIANEDAAQGIAKE NNalign 7019.6 10354.8 1.475 NNalign 75.0 83.0 22 0.5 NA NA NA NA NA NA 7019.6 10354.8 1.475 75.0 83.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.45714285714285713 0.35714285714285715 True False False 0 False 0 10354.8 7019.6 83.0 75.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 9 7 GSHVWTHSRDPEGSS GSHVWTRSRDPEGSS NNalign 7022.9 2287.8 0.326 NNalign 75.0 50.0 56 0.071 NA NA NA NA NA NA 7022.9 2287.8 0.326 75.0 50.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -0.7142857142857143 False False False 0 False 0 2287.8 7022.9 50.0 75.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 5 11 GRSGGSHVWTHSRDP GRSGGSHVWTRSRDP NNalign 7366.4 2532.9 0.344 NNalign 76.0 52.0 56 0.071 NA NA NA NA NA NA 7366.4 2532.9 0.344 76.0 52.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.1714285714285717 -0.31428571428571433 False False True 0 False 0 2532.9 7366.4 52.0 76.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 15 1 APTTVIYEDNQRPSG SPTTVIYEDNQRPSG NNalign 7416.0 7393.4 0.997 NNalign 76.0 76.0 7 0.571 NA NA NA NA NA NA 7416.0 7393.4 0.997 76.0 76.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -2.542857142857143 0.8857142857142858 False False False 0 False 0 7393.4 7416.0 76.0 76.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 6 10 RSGGSHVWTHSRDPE RSGGSHVWTRSRDPE NNalign 7443.0 2332.5 0.313 NNalign 76.0 51.0 56 0.071 NA NA NA NA NA NA 7443.0 2332.5 0.313 76.0 51.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.5428571428571423 -0.31428571428571433 False False False 0 False 0 2332.5 7443.0 51.0 76.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 14 2 TGSSGSIASNYVQWY TRSSGSIASNYVQWY NNalign 7572.9 6349.2 0.838 NNalign 76.0 73.0 5 1.0 NA NA NA NA NA NA 7572.9 6349.2 0.838 76.0 73.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G -1.0142857142857142 0.5857142857142857 False False False 0 False 0 6349.2 7572.9 73.0 76.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 13 3 LHIYGSGGYALYFFP LHTYGSGGYALYFFP NNalign 7636.5 10373.1 1.358 NNalign 77.0 83.0 120 0.233 NA NA NA NA NA NA 7636.5 10373.1 1.358 77.0 83.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 1.0 1.1714285714285713 False False True 0 False 0 10373.1 7636.5 83.0 77.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 8 8 AVQGIANQDAAQGIA AVQGIANEDAAQGIA NNalign 7967.4 10937.4 1.373 NNalign 77.0 84.0 22 0.5 NA NA NA NA NA NA 7967.4 10937.4 1.373 77.0 84.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q 0.35714285714285715 0.7000000000000001 False False False 0 False 0 10937.4 7967.4 84.0 77.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 13 3 KVEMSHFEPNEYIHY KVAMSHFEPNEYIHY NNalign 8012.9 5977.1 0.746 NNalign 77.0 71.0 113 0.044 NA NA NA NA NA NA 8012.9 5977.1 0.746 77.0 71.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -1.4142857142857146 -0.3000000000000001 False False False 0 False 0 5977.1 8012.9 71.0 77.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 14 2 HIYGSGGYALYFFPE HTYGSGGYALYFFPE NNalign 8038.4 10518.4 1.309 NNalign 78.0 83.0 120 0.233 NA NA NA NA NA NA 8038.4 10518.4 1.309 78.0 83.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I 0.6857142857142856 1.1714285714285713 False False False 0 False 0 10518.4 8038.4 83.0 78.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 15 1 LFNCECDLFGFLAWL PFNCECDLFGFLAWL NNalign 8189.2 7919.2 0.967 NNalign 78.0 77.0 303 0.135 NA NA NA NA NA NA 8189.2 7919.2 0.967 78.0 77.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 1.957142857142857 1.9571428571428573 False False False 2 False 0 7919.2 8189.2 77.0 78.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 6 10 LMVCELAGNLFNCEC LMVCELAGNPFNCEC NNalign 8262.7 11031.0 1.335 NNalign 78.0 84.0 303 0.135 NA NA NA NA NA NA 8262.7 11031.0 1.335 78.0 84.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 2.0714285714285716 False True False 3 False 0 11031.0 8262.7 84.0 78.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 4 12 AGRSGGSHVWTHSRD AGRSGGSHVWTRSRD NNalign 8267.2 3705.7 0.448 NNalign 78.0 61.0 56 0.071 NA NA NA NA NA NA 8267.2 3705.7 0.448 78.0 61.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -1.3428571428571427 -0.31428571428571433 False False False 0 False 0 3705.7 8267.2 61.0 78.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 1 15 WSDAVLHHEDLIGKH WSDAVLHHEDLIGKP NNalign 8372.0 9103.5 1.087 NNalign 78.0 80.0 140 0.179 NA NA NA NA NA NA 8372.0 9103.5 1.087 78.0 80.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -0.8857142857142858 0.19999999999999993 False False False 0 False 0 9103.5 8372.0 80.0 78.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 2 14 SESPGKTVTISCTGS SESPGKTVTISCTRS NNalign 8527.1 4801.6 0.563 NNalign 79.0 67.0 5 1.0 NA NA NA NA NA NA 8527.1 4801.6 0.563 79.0 67.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5142857142857142 1.2285714285714284 False False False 1 False 0 4801.6 8527.1 67.0 79.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 11 5 KFNPQTDYLTGTDGK KFNPETDYLTGTDGK NNalign 8570.1 11203.1 1.307 NNalign 79.0 85.0 136 0.25 NA NA NA NA NA NA 8570.1 11203.1 1.307 79.0 85.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -0.8285714285714286 -0.45714285714285713 False False False 0 False 1 11203.1 8570.1 85.0 79.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 12 4 FNPQTDYLTGTDGKK FNPETDYLTGTDGKK NNalign 8579.4 9649.8 1.125 NNalign 79.0 81.0 136 0.25 NA NA NA NA NA NA 8579.4 9649.8 1.125 79.0 81.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -1.9285714285714286 -0.45714285714285713 False False False 0 False 1 9649.8 8579.4 81.0 79.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 12 4 AKVEMSHFEPNEYIH AKVAMSHFEPNEYIH NNalign 8603.8 4308.6 0.501 NNalign 79.0 64.0 113 0.044 NA NA NA NA NA NA 8603.8 4308.6 0.501 79.0 64.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -1.7285714285714289 -0.3000000000000001 False False False 0 False 0 4308.6 8603.8 64.0 79.0 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 15 1 IYGSGGYALYFFPEQ TYGSGGYALYFFPEQ NNalign 8729.0 8988.9 1.03 NNalign 79.0 80.0 120 0.233 NA NA NA NA NA NA 8729.0 8988.9 1.03 79.0 80.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.07142857142857142 1.1714285714285713 False False False 0 False 0 8988.9 8729.0 80.0 79.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 1 15 KKEEVKSPVKEEEKT KKEEVKSPVKEEEKP NNalign 8808.8 9106.7 1.034 NNalign 79.0 80.0 185 0.038 NA NA NA NA NA NA 8808.8 9106.7 1.034 79.0 80.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -0.7 False False False 0 False 0 9106.7 8808.8 80.0 79.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 1 15 MQDSRQKAVRPLELV MQDSRQKAVRPLELA NNalign 8932.5 7592.2 0.85 NNalign 80.0 77.0 113 0.053 NA NA NA NA NA NA 8932.5 7592.2 0.85 80.0 77.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 0.9142857142857144 0.9142857142857144 False False False 0 False 0 7592.2 8932.5 77.0 80.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 3 13 RAGRSGGSHVWTHSR RAGRSGGSHVWTRSR NNalign 8973.0 5981.0 0.667 NNalign 80.0 71.0 56 0.071 NA NA NA NA NA NA 8973.0 5981.0 0.667 80.0 71.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -1.3000000000000003 -0.31428571428571433 False False False 0 False 0 5981.0 8973.0 71.0 80.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 14 2 VEMSHFEPNEYIHYD VAMSHFEPNEYIHYD NNalign 9021.3 8528.2 0.945 NNalign 80.0 79.0 113 0.044 NA NA NA NA NA NA 9021.3 8528.2 0.945 80.0 79.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -1.6857142857142857 -0.3000000000000001 False False False 0 False 0 8528.2 9021.3 79.0 80.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 2 14 KEEVKSPVKEEEKTQ KEEVKSPVKEEEKPQ NNalign 9082.5 9612.2 1.058 NNalign 80.0 81.0 185 0.038 NA NA NA NA NA NA 9082.5 9612.2 1.058 80.0 81.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -3.2142857142857144 -0.7 False False False 0 False 0 9612.2 9082.5 81.0 80.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 15 1 EMSHFEPNEYIHYDL AMSHFEPNEYIHYDL NNalign 9213.4 8815.5 0.957 NNalign 80.0 79.0 113 0.044 NA NA NA NA NA NA 9213.4 8815.5 0.957 80.0 79.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -0.642857142857143 -0.642857142857143 True False False 0 False 0 8815.5 9213.4 79.0 80.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 12 4 EEKTQEVKVKEPPKK EEKPQEVKVKEPPKK NNalign 9292.1 10793.5 1.162 NNalign 81.0 84.0 185 0.038 NA NA NA NA NA NA 9292.1 10793.5 1.162 81.0 84.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.028571428571429 -0.8714285714285713 True False False 0 False 0 10793.5 9292.1 84.0 81.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 8 8 TVTISCTGSSGSIAS TVTISCTRSSGSIAS NNalign 9296.2 1259.8 0.136 NNalign 81.0 39.0 5 1.0 NA NA NA NA NA NA 9296.2 1259.8 0.136 81.0 39.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.38571428571428573 1.2285714285714284 False False False 1 False 0 1259.8 9296.2 39.0 81.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 10 6 SHVWTHSRDPEGSSR SHVWTRSRDPEGSSR NNalign 9513.4 4159.3 0.437 NNalign 81.0 63.0 56 0.071 NA NA NA NA NA NA 9513.4 4159.3 0.437 81.0 63.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.1571428571428575 -0.7714285714285714 False False False 0 False 0 4159.3 9513.4 63.0 81.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 14 2 NLFNCECDLFGFLAW NPFNCECDLFGFLAW NNalign 9516.9 9675.3 1.017 NNalign 81.0 82.0 303 0.135 NA NA NA NA NA NA 9516.9 9675.3 1.017 81.0 82.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 1.9571428571428573 1.9571428571428573 False False False 2 True 0 9675.3 9516.9 82.0 81.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 13 3 GNLFNCECDLFGFLA GNPFNCECDLFGFLA NNalign 9579.1 11256.4 1.175 NNalign 81.0 85.0 303 0.135 NA NA NA NA NA NA 9579.1 11256.4 1.175 81.0 85.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 1.5857142857142859 1.6857142857142855 False False False 2 False 0 11256.4 9579.1 85.0 81.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 2 14 GISKEDAVQGIANQD GISKEDAVQGIANED NNalign 9861.7 10713.1 1.086 NNalign 82.0 84.0 22 0.5 NA NA NA NA NA NA 9861.7 10713.1 1.086 82.0 84.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.157142857142857 0.7000000000000001 False False False 0 False 0 10713.1 9861.7 84.0 82.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 7 9 DAVQGIANQDAAQGI DAVQGIANEDAAQGI NNalign 10073.4 13243.2 1.315 NNalign 82.0 88.0 22 0.5 NA NA NA NA NA NA 10073.4 13243.2 1.315 82.0 88.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 0.7000000000000001 False False False 0 False 0 13243.2 10073.4 88.0 82.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 5 11 GMYQPCDDMDYLSDR GMYQPCDDMDCLSDR NNalign 10346.1 15063.8 1.456 NNalign 83.0 90.0 92 0.043 NA NA NA NA NA NA 10346.1 15063.8 1.456 83.0 90.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.1285714285714286 -0.5142857142857142 False False False 1 False 0 15063.8 10346.1 90.0 83.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 11 5 GIANQDAAQGIAKED GIANEDAAQGIAKED NNalign 10362.6 13789.3 1.331 NNalign 83.0 88.0 22 0.5 NA NA NA NA NA NA 10362.6 13789.3 1.331 83.0 88.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.2142857142857142 0.35714285714285715 False False False 0 False 0 13789.3 10362.6 88.0 83.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 7 9 LHTVSPEPARPPQQP LHTVSPEPPRPPQQP NNalign 10467.1 20671.4 1.975 NNalign 83.0 95.0 245 0.486 NA NA NA NA NA NA 10467.1 20671.4 1.975 83.0 95.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -2.0714285714285716 -0.2571428571428572 False False True 0 False 0 20671.4 10467.1 95.0 83.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 13 3 CTGSSGSIASNYVQW CTRSSGSIASNYVQW NNalign 10575.4 7631.3 0.722 NNalign 83.0 77.0 5 1.0 NA NA NA NA NA NA 10575.4 7631.3 0.722 83.0 77.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.5714285714285714 0.5857142857142857 True False False 1 False 0 7631.3 10575.4 77.0 83.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 7 9 MVCELAGNLFNCECD MVCELAGNPFNCECD NNalign 10641.2 15002.9 1.41 NNalign 84.0 90.0 303 0.135 NA NA NA NA NA NA 10641.2 15002.9 1.41 84.0 90.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 1.4714285714285713 False False False 3 False 0 15002.9 10641.2 90.0 84.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 4 12 LGMYQPCDDMDYLSD LGMYQPCDDMDCLSD NNalign 10797.4 16078.5 1.489 NNalign 84.0 91.0 92 0.043 NA NA NA NA NA NA 10797.4 16078.5 1.489 84.0 91.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142857 0.19999999999999998 False False False 1 False 0 16078.5 10797.4 91.0 84.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 1 15 RSRAGRSGGSHVWTH RSRAGRSGGSHVWTR NNalign 11226.5 9472.9 0.844 NNalign 85.0 81.0 56 0.071 NA NA NA NA NA NA 11226.5 9472.9 0.844 85.0 81.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -0.7142857142857143 -0.31428571428571433 False False False 0 False 0 9472.9 11226.5 81.0 85.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 3 13 TLGMYQPCDDMDYLS TLGMYQPCDDMDCLS NNalign 11323.2 16563.6 1.463 NNalign 85.0 91.0 92 0.043 NA NA NA NA NA NA 11323.2 16563.6 1.463 85.0 91.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.9857142857142858 0.19999999999999998 False False False 1 False 0 16563.6 11323.2 91.0 85.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 11 5 HVWTHSRDPEGSSRK HVWTRSRDPEGSSRK NNalign 11421.2 8447.8 0.74 NNalign 85.0 79.0 56 0.071 NA NA NA NA NA NA 11421.2 8447.8 0.74 85.0 79.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.2142857142857144 -1.3000000000000003 False False False 0 False 0 8447.8 11421.2 79.0 85.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 7 9 KSVNEALNNLLTEEE KSVNEALNHLLTEEE NNalign 11571.6 5425.5 0.469 NNalign 85.0 69.0 30 0.1 NA NA NA NA NA NA 11571.6 5425.5 0.469 85.0 69.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.7857142857142856 False False False 0 False 0 5425.5 11571.6 69.0 85.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 6 10 NKSVNEALNNLLTEE NKSVNEALNHLLTEE NNalign 11654.6 5454.1 0.468 NNalign 85.0 69.0 30 0.1 NA NA NA NA NA NA 11654.6 5454.1 0.468 85.0 69.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.7857142857142856 False False False 0 True 0 5454.1 11654.6 69.0 85.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 2 14 SRAGRSGGSHVWTHS SRAGRSGGSHVWTRS NNalign 11758.2 9339.0 0.794 NNalign 85.0 81.0 56 0.071 NA NA NA NA NA NA 11758.2 9339.0 0.794 85.0 81.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -0.7714285714285714 -0.31428571428571433 False False False 0 False 0 9339.0 11758.2 81.0 85.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 21 NA SGEKAGCPWSGTGQH NA NNalign 11805.0 NA NA NNalign 86.0 NA 142 0.768 NA NA NA NA NA NA 11805.0 NA NA 86.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.4142857142857141 0.02857142857142855 False False False 1 False 0 NA 11805.0 NA 86.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 5 11 NNKSVNEALNNLLTE NNKSVNEALNHLLTE NNalign 12010.4 6112.8 0.509 NNalign 86.0 72.0 30 0.1 NA NA NA NA NA NA 12010.4 6112.8 0.509 86.0 72.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.02857142857142847 0.7857142857142856 False False False 0 True 0 6112.8 12010.4 72.0 86.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 14 2 SAPTTVIYEDNQRPS SSPTTVIYEDNQRPS NNalign 12088.2 12232.7 1.012 NNalign 86.0 86.0 7 0.571 NA NA NA NA NA NA 12088.2 12232.7 1.012 86.0 86.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -2.985714285714286 0.9571428571428572 False False False 0 False 0 12232.7 12088.2 86.0 86.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 3 13 EEVKSPVKEEEKTQE EEVKSPVKEEEKPQE NNalign 12097.4 12631.1 1.044 NNalign 86.0 87.0 185 0.038 NA NA NA NA NA NA 12097.4 12631.1 1.044 86.0 87.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -3.1571428571428575 -0.7 True False False 0 False 0 12631.1 12097.4 87.0 86.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 6 10 EDAVQGIANQDAAQG EDAVQGIANEDAAQG NNalign 12788.6 15541.4 1.215 NNalign 87.0 90.0 22 0.5 NA NA NA NA NA NA 12788.6 15541.4 1.215 87.0 90.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.5428571428571427 0.7000000000000001 True False False 0 False 0 15541.4 12788.6 90.0 87.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 1 15 VSESPGKTVTISCTG VSESPGKTVTISCTR NNalign 13111.9 9707.0 0.74 NNalign 87.0 82.0 5 1.0 NA NA NA NA NA NA 13111.9 9707.0 0.74 87.0 82.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G 1.2285714285714284 1.2285714285714284 False False False 1 False 0 9707.0 13111.9 82.0 87.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 12 4 AGNLFNCECDLFGFL AGNPFNCECDLFGFL NNalign 13294.9 17456.1 1.313 NNalign 88.0 92.0 303 0.135 NA NA NA NA NA NA 13294.9 17456.1 1.313 88.0 92.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 1.6857142857142855 1.6857142857142855 False False False 2 False 0 17456.1 13294.9 92.0 88.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 3 13 ISKEDAVQGIANQDA ISKEDAVQGIANEDA NNalign 13495.0 15106.1 1.119 NNalign 88.0 90.0 22 0.5 NA NA NA NA NA NA 13495.0 15106.1 1.119 88.0 90.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 0.7000000000000001 False False False 0 False 0 15106.1 13495.0 90.0 88.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 2 14 VTLGMYQPCDDMDYL VTLGMYQPCDDMDCL NNalign 13507.2 18028.3 1.335 NNalign 88.0 93.0 92 0.043 NA NA NA NA NA NA 13507.2 18028.3 1.335 88.0 93.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -0.5142857142857142 0.5714285714285713 False False False 1 False 0 18028.3 13507.2 93.0 88.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 5 11 KEDAVQGIANQDAAQ KEDAVQGIANEDAAQ NNalign 13530.0 15228.0 1.125 NNalign 88.0 90.0 22 0.5 NA NA NA NA NA NA 13530.0 15228.0 1.125 88.0 90.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.2285714285714284 0.7000000000000001 False False False 0 False 0 15228.0 13530.0 90.0 88.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 8 8 SVNEALNNLLTEEED SVNEALNHLLTEEED NNalign 13618.2 7396.5 0.543 NNalign 88.0 76.0 30 0.1 NA NA NA NA NA NA 13618.2 7396.5 0.543 88.0 76.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.0142857142857145 0.7857142857142856 False False False 0 False 0 7396.5 13618.2 76.0 88.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 4 12 HNNKSVNEALNNLLT HNNKSVNEALNHLLT NNalign 13907.0 7919.2 0.569 NNalign 88.0 77.0 30 0.1 NA NA NA NA NA NA 13907.0 7919.2 0.569 88.0 77.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.7857142857142856 0.7857142857142856 False False False 0 False 0 7919.2 13907.0 77.0 88.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 11 5 EEEKTQEVKVKEPPK EEEKPQEVKVKEPPK NNalign 13934.4 16895.3 1.212 NNalign 88.0 92.0 185 0.038 NA NA NA NA NA NA 13934.4 16895.3 1.212 88.0 92.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.0285714285714285 -0.8714285714285713 True False False 0 False 0 16895.3 13934.4 92.0 88.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 8 8 VCELAGNLFNCECDL VCELAGNPFNCECDL NNalign 14003.3 19702.7 1.407 NNalign 88.0 94.0 303 0.135 NA NA NA NA NA NA 14003.3 19702.7 1.407 88.0 94.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.7000000000000001 False False False 3 False 0 19702.7 14003.3 94.0 88.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 1 15 LSHAAREERTEASGY LSHAAREERTEASGS NNalign 14140.8 13690.0 0.968 NNalign 89.0 88.0 116 0.043 NA NA NA NA NA NA 14140.8 13690.0 0.968 89.0 88.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.342857142857143 -0.6571428571428571 False False False 0 False 0 13690.0 14140.8 88.0 89.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 5 13 LPLPPPPLLPLLPLL LPLPPPPLLPLLLLL NNalign 14152.1 16948.4 1.198 NNalign 89.0 92.0 101 0.891 NA NA NA NA NA NA 14152.1 16948.4 1.198 89.0 92.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 16948.4 14152.1 92.0 89.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 7 9 YQPCDDMDYLSDRCK YQPCDDMDCLSDRCK NNalign 14360.2 22209.2 1.547 NNalign 89.0 95.0 92 0.043 NA NA NA NA NA NA 14360.2 22209.2 1.547 89.0 95.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.0999999999999999 -0.5142857142857142 False False False 2 False 0 22209.2 14360.2 95.0 89.0 -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-DRB1*11:01 15 8 1 SAAAAAAAVIPTVST AAAAAAAAVIPTVST NNalign 14537.0 14673.4 1.009 NNalign 89.0 89.0 128 0.977 NA NA NA NA NA NA 14537.0 14673.4 1.009 89.0 89.0 NA NA NA NA NA NA NA NA 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 1.3 2.5285714285714285 False False False 0 False 0 14673.4 14537.0 89.0 89.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 1 15 CVTLGMYQPCDDMDY CVTLGMYQPCDDMDC NNalign 14580.6 17384.9 1.192 NNalign 89.0 92.0 92 0.043 NA NA NA NA NA NA 14580.6 17384.9 1.192 89.0 92.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.2857142857142858 1.4285714285714286 True False False 2 False 0 17384.9 14580.6 92.0 89.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 11 5 LAGNLFNCECDLFGF LAGNPFNCECDLFGF NNalign 14648.5 20053.2 1.369 NNalign 89.0 94.0 303 0.135 NA NA NA NA NA NA 14648.5 20053.2 1.369 89.0 94.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6428571428571429 0.6857142857142856 False False False 2 False 0 20053.2 14648.5 94.0 89.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 4 12 SKEDAVQGIANQDAA SKEDAVQGIANEDAA NNalign 14898.0 17086.1 1.147 NNalign 90.0 92.0 22 0.5 NA NA NA NA NA NA 14898.0 17086.1 1.147 90.0 92.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.08571428571428576 0.7000000000000001 False False False 0 False 0 17086.1 14898.0 92.0 90.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 15 1 QDAAQGIAKEDPVQG EDAAQGIAKEDPVQG NNalign 14962.1 15604.4 1.043 NNalign 90.0 90.0 22 0.5 NA NA NA NA NA NA 14962.1 15604.4 1.043 90.0 90.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.742857142857143 0.35714285714285715 True False False 0 False 0 15604.4 14962.1 90.0 90.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 4 12 EVKSPVKEEEKTQEV EVKSPVKEEEKPQEV NNalign 15173.4 15892.4 1.047 NNalign 90.0 91.0 185 0.038 NA NA NA NA NA NA 15173.4 15892.4 1.047 90.0 91.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.0571428571428574 -0.757142857142857 True False False 0 False 0 15892.4 15173.4 91.0 90.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 9 7 CELAGNLFNCECDLF CELAGNPFNCECDLF NNalign 15494.2 21999.9 1.42 NNalign 90.0 95.0 303 0.135 NA NA NA NA NA NA 15494.2 21999.9 1.42 90.0 95.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.15714285714285708 0.6857142857142856 True False False 3 False 0 21999.9 15494.2 95.0 90.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 9 7 VNEALNNLLTEEEDY VNEALNHLLTEEEDY NNalign 15533.0 11128.3 0.716 NNalign 90.0 84.0 30 0.1 NA NA NA NA NA NA 15533.0 11128.3 0.716 90.0 84.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.742857142857143 0.7857142857142856 False False False 0 False 0 11128.3 15533.0 84.0 90.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 12 4 IANQDAAQGIAKEDP IANEDAAQGIAKEDP NNalign 15600.7 18451.1 1.183 NNalign 90.0 93.0 22 0.5 NA NA NA NA NA NA 15600.7 18451.1 1.183 90.0 93.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.9428571428571428 0.35714285714285715 False False True 0 False 0 18451.1 15600.7 93.0 90.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 6 10 MYQPCDDMDYLSDRC MYQPCDDMDCLSDRC NNalign 16012.2 22454.7 1.402 NNalign 91.0 96.0 92 0.043 NA NA NA NA NA NA 16012.2 22454.7 1.402 91.0 96.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y -1.042857142857143 -0.5142857142857142 False True False 2 False 0 22454.7 16012.2 96.0 91.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 20 NA GSGEKAGCPWSGTGQ NA NNalign 16146.8 NA NA NNalign 91.0 NA 142 0.768 NA NA NA NA NA NA 16146.8 NA NA 91.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.1857142857142857 0.02857142857142855 False False False 1 False 0 NA 16146.8 NA 91.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 12 4 SCTGSSGSIASNYVQ SCTRSSGSIASNYVQ NNalign 16163.3 8555.1 0.529 NNalign 91.0 79.0 5 1.0 NA NA NA NA NA NA 16163.3 8555.1 0.529 91.0 79.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.20000000000000004 0.5857142857142857 False False False 1 False 0 8555.1 16163.3 79.0 91.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 13 3 SGYESRVEPPHENGN SGSESRVEPPHENGN NNalign 16811.1 27393.4 1.629 NNalign 91.0 98.0 116 0.043 NA NA NA NA NA NA 16811.1 27393.4 1.629 91.0 98.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -2.4714285714285715 -1.0142857142857145 False False False 0 False 0 27393.4 16811.1 98.0 91.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 14 2 NQDAAQGIAKEDPVQ NEDAAQGIAKEDPVQ NNalign 16816.2 18027.2 1.072 NNalign 91.0 93.0 22 0.5 NA NA NA NA NA NA 16816.2 18027.2 1.072 91.0 93.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -1.4285714285714286 0.35714285714285715 False False False 0 True 0 18027.2 16816.2 93.0 91.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 8 8 HTVSPEPARPPQQPV HTVSPEPPRPPQQPV NNalign 16855.9 25404.9 1.507 NNalign 92.0 97.0 245 0.486 NA NA NA NA NA NA 16855.9 25404.9 1.507 92.0 97.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -1.7285714285714289 -0.31428571428571433 False False False 0 False 0 25404.9 16855.9 97.0 92.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 10 6 ELAGNLFNCECDLFG ELAGNPFNCECDLFG NNalign 16881.3 23106.4 1.369 NNalign 92.0 96.0 303 0.135 NA NA NA NA NA NA 16881.3 23106.4 1.369 92.0 96.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.5999999999999999 0.6857142857142856 True False False 2 False 0 23106.4 16881.3 96.0 92.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 14 2 GYESRVEPPHENGNR GSESRVEPPHENGNR NNalign 17057.3 24851.7 1.457 NNalign 92.0 97.0 116 0.043 NA NA NA NA NA NA 17057.3 24851.7 1.457 92.0 97.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -2.885714285714286 -1.4000000000000001 False False False 0 False 0 24851.7 17057.3 97.0 92.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 9 7 VTISCTGSSGSIASN VTISCTRSSGSIASN NNalign 17184.8 2803.5 0.163 NNalign 92.0 54.0 5 1.0 NA NA NA NA NA NA 17184.8 2803.5 0.163 92.0 54.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.0 1.2285714285714284 False False False 1 False 0 2803.5 17184.8 54.0 92.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 12 4 ASGYESRVEPPHENG ASGSESRVEPPHENG NNalign 17588.3 28577.5 1.625 NNalign 92.0 98.0 116 0.043 NA NA NA NA NA NA 17588.3 28577.5 1.625 92.0 98.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -2.471428571428571 -1.0142857142857145 False False False 0 False 0 28577.5 17588.3 98.0 92.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 3 13 SHNNKSVNEALNNLL SHNNKSVNEALNHLL NNalign 17648.1 12235.3 0.693 NNalign 92.0 86.0 30 0.1 NA NA NA NA NA NA 17648.1 12235.3 0.693 92.0 86.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N 0.3857142857142856 0.3857142857142856 False False False 0 False 0 12235.3 17648.1 86.0 92.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 5 11 VKSPVKEEEKTQEVK VKSPVKEEEKPQEVK NNalign 17708.2 18026.0 1.018 NNalign 92.0 93.0 185 0.038 NA NA NA NA NA NA 17708.2 18026.0 1.018 92.0 93.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.1142857142857143 -0.757142857142857 False False False 0 False 0 18026.0 17708.2 93.0 92.0 -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-DRB1*11:01 15 13 3 ANQDAAQGIAKEDPV ANEDAAQGIAKEDPV NNalign 17741.6 19515.8 1.1 NNalign 92.0 94.0 22 0.5 NA NA NA NA NA NA 17741.6 19515.8 1.1 92.0 94.0 NA NA NA NA NA NA NA NA 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.2857142857142856 0.35714285714285715 False False False 0 False 0 19515.8 17741.6 94.0 92.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 19 NA QGSGEKAGCPWSGTG NA NNalign 18445.1 NA NA NNalign 93.0 NA 142 0.768 NA NA NA NA NA NA 18445.1 NA NA 93.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.3285714285714286 0.02857142857142855 True False False 1 False 0 NA 18445.1 NA 93.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 12 4 VWTHSRDPEGSSRKQ VWTRSRDPEGSSRKQ NNalign 18891.8 16714.1 0.885 NNalign 93.0 91.0 56 0.071 NA NA NA NA NA NA 18891.8 16714.1 0.885 93.0 91.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.4857142857142853 -1.3428571428571427 False False False 0 False 0 16714.1 18891.8 91.0 93.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 2 14 QSHNNKSVNEALNNL QSHNNKSVNEALNHL NNalign 19200.7 16077.8 0.837 NNalign 93.0 91.0 30 0.1 NA NA NA NA NA NA 19200.7 16077.8 0.837 93.0 91.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6571428571428573 -0.21428571428571427 True False False 0 False 0 16077.8 19200.7 91.0 93.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 10 6 NEALNNLLTEEEDYQ NEALNHLLTEEEDYQ NNalign 19215.5 14765.6 0.768 NNalign 93.0 90.0 30 0.1 NA NA NA NA NA NA 19215.5 14765.6 0.768 93.0 90.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -2.7857142857142856 0.7857142857142856 False False False 0 True 0 14765.6 19215.5 90.0 93.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 1 15 VQSHNNKSVNEALNN VQSHNNKSVNEALNH NNalign 19393.4 18568.8 0.957 NNalign 94.0 93.0 30 0.1 NA NA NA NA NA NA 19393.4 18568.8 0.957 94.0 93.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6 -0.21428571428571427 False False False 0 False 0 18568.8 19393.4 93.0 94.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 18 NA GQGSGEKAGCPWSGT NA NNalign 19407.5 NA NA NNalign 94.0 NA 142 0.768 NA NA NA NA NA NA 19407.5 NA NA 94.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.32857142857142857 0.02857142857142855 False False False 1 False 0 NA 19407.5 NA 94.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 11 5 EASGYESRVEPPHEN EASGSESRVEPPHEN NNalign 19617.2 30996.5 1.58 NNalign 94.0 99.0 116 0.043 NA NA NA NA NA NA 19617.2 30996.5 1.58 94.0 99.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.8142857142857143 -1.0142857142857145 True False False 0 False 0 30996.5 19617.2 99.0 94.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 10 6 KEEEKTQEVKVKEPP KEEEKPQEVKVKEPP NNalign 19635.0 24468.3 1.246 NNalign 94.0 97.0 185 0.038 NA NA NA NA NA NA 19635.0 24468.3 1.246 94.0 97.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -0.8714285714285713 -0.8714285714285713 False False True 0 False 0 24468.3 19635.0 97.0 94.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 15 1 NLLTEEEDYQGLRAS HLLTEEEDYQGLRAS NNalign 20121.2 20170.1 1.002 NNalign 94.0 94.0 30 0.1 NA NA NA NA NA NA 20121.2 20170.1 1.002 94.0 94.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.7000000000000001 -0.7000000000000001 False False False 0 True 0 20170.1 20121.2 94.0 94.0 -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-DRB1*11:01 15 7 2 ASAAAAAAAVIPTVS AAAAAAAAAVIPTVS NNalign 20183.8 21026.4 1.042 NNalign 94.0 95.0 128 0.977 NA NA NA NA NA NA 20183.8 21026.4 1.042 94.0 95.0 NA NA NA NA NA NA NA NA 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 1.6571428571428573 2.5285714285714285 False False False 0 False 0 21026.4 20183.8 95.0 94.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 13 3 GSAPTTVIYEDNQRP GSSPTTVIYEDNQRP NNalign 20468.4 20949.0 1.023 NNalign 94.0 95.0 7 0.571 NA NA NA NA NA NA 20468.4 20949.0 1.023 94.0 95.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -3.0571428571428574 0.9571428571428572 False False True 0 False 0 20949.0 20468.4 95.0 94.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 15 1 YESRVEPPHENGNRS SESRVEPPHENGNRS NNalign 20590.4 25634.1 1.245 NNalign 94.0 97.0 116 0.043 NA NA NA NA NA NA 20590.4 25634.1 1.245 94.0 97.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -2.771428571428572 -1.5714285714285712 False False False 0 False 0 25634.1 20590.4 97.0 94.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 13 3 WTHSRDPEGSSRKQQ WTRSRDPEGSSRKQQ NNalign 21188.1 20577.2 0.971 NNalign 95.0 94.0 56 0.071 NA NA NA NA NA NA 21188.1 20577.2 0.971 95.0 94.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.4857142857142853 -2.1571428571428575 False False False 0 False 0 20577.2 21188.1 94.0 95.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 9 7 VKEEEKTQEVKVKEP VKEEEKPQEVKVKEP NNalign 21891.7 26386.6 1.205 NNalign 95.0 98.0 185 0.038 NA NA NA NA NA NA 21891.7 26386.6 1.205 95.0 98.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -1.1428571428571428 -1.014285714285714 False False True 0 False 0 26386.6 21891.7 98.0 95.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 8 8 PVKEEEKTQEVKVKE PVKEEEKPQEVKVKE NNalign 22229.2 24196.3 1.088 NNalign 95.0 97.0 185 0.038 NA NA NA NA NA NA 22229.2 24196.3 1.088 95.0 97.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -1.4142857142857141 -1.014285714285714 False False False 0 False 0 24196.3 22229.2 97.0 95.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 10 6 TISCTGSSGSIASNY TISCTRSSGSIASNY NNalign 22337.2 5342.0 0.239 NNalign 96.0 69.0 5 1.0 NA NA NA NA NA NA 22337.2 5342.0 0.239 96.0 69.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.07142857142857147 0.5142857142857142 False False False 1 False 0 5342.0 22337.2 69.0 96.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 17 NA TGQGSGEKAGCPWSG NA NNalign 22421.7 NA NA NNalign 96.0 NA 142 0.768 NA NA NA NA NA NA 22421.7 NA NA 96.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G 0.02857142857142855 0.02857142857142855 False False False 1 False 0 NA 22421.7 NA 96.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 15 1 HSRDPEGSSRKQQPM RSRDPEGSSRKQQPM NNalign 22532.6 22197.4 0.985 NNalign 96.0 95.0 56 0.071 NA NA NA NA NA NA 22532.6 22197.4 0.985 96.0 95.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.2714285714285714 -2.1571428571428575 False False False 0 False 0 22197.4 22532.6 95.0 96.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 10 6 TEASGYESRVEPPHE TEASGSESRVEPPHE NNalign 22552.1 33353.3 1.479 NNalign 96.0 100.0 116 0.043 NA NA NA NA NA NA 22552.1 33353.3 1.479 96.0 100.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.957142857142857 -1.0142857142857145 False False False 0 False 0 33353.3 22552.1 100.0 96.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 11 5 ISCTGSSGSIASNYV ISCTRSSGSIASNYV NNalign 22665.4 8301.9 0.366 NNalign 96.0 78.0 5 1.0 NA NA NA NA NA NA 22665.4 8301.9 0.366 96.0 78.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G 0.5857142857142857 0.5857142857142857 False False False 1 False 0 8301.9 22665.4 78.0 96.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 7 9 SPVKEEEKTQEVKVK SPVKEEEKPQEVKVK NNalign 22676.1 24200.8 1.067 NNalign 96.0 97.0 185 0.038 NA NA NA NA NA NA 22676.1 24200.8 1.067 96.0 97.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -1.0142857142857142 -1.014285714285714 False False False 0 False 0 24200.8 22676.1 97.0 96.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-DRB1*11:01 15 14 2 THSRDPEGSSRKQQP TRSRDPEGSSRKQQP NNalign 23095.6 23006.8 0.996 NNalign 96.0 96.0 56 0.071 NA NA NA NA NA NA 23095.6 23006.8 0.996 96.0 96.0 NA NA NA NA NA NA NA NA 5.CECR2.ENST00000262608.8.missense.535R/H -2.6571428571428575 -2.1571428571428575 False False True 0 False 0 23006.8 23095.6 96.0 96.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 4 14 ALPLPPPPLLPLLPL ALPLPPPPLLPLLLL NNalign 23322.6 23262.6 0.997 NNalign 96.0 96.0 101 0.891 NA NA NA NA NA NA 23322.6 23262.6 0.997 96.0 96.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 2.257142857142857 2.257142857142857 False False False 0 False 0 23262.6 23322.6 96.0 96.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 9 7 TVSPEPARPPQQPVP TVSPEPPRPPQQPVP NNalign 23623.1 30883.7 1.307 NNalign 96.0 99.0 245 0.486 NA NA NA NA NA NA 23623.1 30883.7 1.307 96.0 99.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -1.3142857142857143 -0.31428571428571433 False False True 0 False 0 30883.7 23623.1 99.0 96.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 8 8 YQQRPGSAPTTVIYE YQQRPGSSPTTVIYE NNalign 23802.7 25564.6 1.074 NNalign 96.0 97.0 7 0.571 NA NA NA NA NA NA 23802.7 25564.6 1.074 96.0 97.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A 0.12857142857142861 0.9571428571428572 False False False 0 False 0 25564.6 23802.7 97.0 96.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 6 10 KSPVKEEEKTQEVKV KSPVKEEEKPQEVKV NNalign 23920.6 24508.5 1.025 NNalign 96.0 97.0 185 0.038 NA NA NA NA NA NA 23920.6 24508.5 1.025 96.0 97.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -1.014285714285714 -1.014285714285714 False False False 0 False 0 24508.5 23920.6 97.0 96.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 15 1 ARPPQQPVPTELSLA PRPPQQPVPTELSLA NNalign 24309.4 24197.9 0.995 NNalign 97.0 97.0 245 0.486 NA NA NA NA NA NA 24309.4 24197.9 0.995 97.0 97.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A 0.39999999999999997 0.7428571428571429 False False False 0 False 0 24197.9 24309.4 97.0 97.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 12 4 PGSAPTTVIYEDNQR PGSSPTTVIYEDNQR NNalign 24754.8 25715.5 1.039 NNalign 97.0 97.0 7 0.571 NA NA NA NA NA NA 24754.8 25715.5 1.039 97.0 97.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -2.185714285714286 0.9571428571428572 False False False 0 False 0 25715.5 24754.8 97.0 97.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 2 14 SHAAREERTEASGYE SHAAREERTEASGSE NNalign 25050.4 24150.3 0.964 NNalign 97.0 97.0 116 0.043 NA NA NA NA NA NA 25050.4 24150.3 0.964 97.0 97.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2 -1.2 False False False 0 False 0 24150.3 25050.4 97.0 97.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 2 15 QKKEDTGGGGRSAGS QKKEDTGGGGRSAGQ NNalign 25233.7 25215.7 0.999 NNalign 97.0 97.0 142 0.768 NA NA NA NA NA NA 25233.7 25215.7 0.999 97.0 97.0 NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.7285714285714285 True False False 0 False 0 25215.7 25233.7 97.0 97.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 9 7 RTEASGYESRVEPPH RTEASGSESRVEPPH NNalign 25687.1 33642.9 1.31 NNalign 97.0 100.0 116 0.043 NA NA NA NA NA NA 25687.1 33642.9 1.31 97.0 100.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285714 -1.0142857142857145 False False False 0 False 0 33642.9 25687.1 100.0 97.0 -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-DRB1*11:01 15 6 1, 3 PASAAAAAAAVIPTV AAAAAAAAAAVIPTV NNalign 25838.8 27383.3 1.06 NNalign 97.0 98.0 128 0.977 NA NA NA NA NA NA 25838.8 27383.3 1.06 97.0 98.0 NA NA NA NA NA NA NA NA 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.028571428571429 2.5285714285714285 False False False 0 False 0 27383.3 25838.8 98.0 97.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 3 15 PALPLPPPPLLPLLP PALPLPPPPLLPLLL NNalign 25937.6 25720.2 0.992 NNalign 97.0 97.0 101 0.891 NA NA NA NA NA NA 25937.6 25720.2 0.992 97.0 97.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.4857142857142858 1.4857142857142858 False False True 0 False 0 25720.2 25937.6 97.0 97.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 14 2 NNLLTEEEDYQGLRA NHLLTEEEDYQGLRA NNalign 26093.9 25418.7 0.974 NNalign 97.0 97.0 30 0.1 NA NA NA NA NA NA 26093.9 25418.7 0.974 97.0 97.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.085714285714286 -1.0142857142857145 False False False 0 True 0 25418.7 26093.9 97.0 97.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 11 5 EALNNLLTEEEDYQG EALNHLLTEEEDYQG NNalign 26132.9 20670.9 0.791 NNalign 97.0 95.0 30 0.1 NA NA NA NA NA NA 26132.9 20670.9 0.791 97.0 95.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -2.742857142857143 0.7857142857142856 True False False 0 False 0 20670.9 26132.9 95.0 97.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 8 9, 10, 11, 12, 13, 14, 15 GGGGRSAGSTGQGSG GGGGRSAGQHWARLR NNalign 26225.2 5774.7 0.22 NNalign 98.0 71.0 142 0.768 NA NA NA NA NA NA 26225.2 5774.7 0.22 98.0 71.0 NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 5774.7 26225.2 71.0 98.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 6 10 REERTEASGYESRVE REERTEASGSESRVE NNalign 26466.6 29750.5 1.124 NNalign 98.0 99.0 116 0.043 NA NA NA NA NA NA 26466.6 29750.5 1.124 98.0 99.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.4000000000000001 -1.0142857142857145 False False False 0 False 0 29750.5 26466.6 99.0 98.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 4 12 AAREERTEASGYESR AAREERTEASGSESR NNalign 26500.2 27804.9 1.049 NNalign 98.0 98.0 116 0.043 NA NA NA NA NA NA 26500.2 27804.9 1.049 98.0 98.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.3571428571428572 -1.2 False False False 0 False 0 27804.9 26500.2 98.0 98.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 5 11 AREERTEASGYESRV AREERTEASGSESRV NNalign 26569.6 29389.6 1.106 NNalign 98.0 99.0 116 0.043 NA NA NA NA NA NA 26569.6 29389.6 1.106 98.0 99.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.0142857142857145 -1.0142857142857145 False False False 0 False 0 29389.6 26569.6 99.0 98.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 3 13 HAAREERTEASGYES HAAREERTEASGSES NNalign 26652.9 26380.0 0.99 NNalign 98.0 98.0 116 0.043 NA NA NA NA NA NA 26652.9 26380.0 0.99 98.0 98.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.2142857142857142 -1.2 False False False 0 False 0 26380.0 26652.9 98.0 98.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 9 NA GGGRSAGSTGQGSGE NA NNalign 27137.6 NA NA NNalign 98.0 NA 142 0.768 NA NA NA NA NA NA 27137.6 NA NA 98.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.3857142857142857 -0.6285714285714287 False False False 0 False 0 NA 27137.6 NA 98.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 3 14, 15 KKEDTGGGGRSAGST KKEDTGGGGRSAGQH NNalign 27284.6 26196.8 0.96 NNalign 98.0 98.0 142 0.768 NA NA NA NA NA NA 27284.6 26196.8 0.96 98.0 98.0 NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7285714285714285 False False False 0 False 0 26196.8 27284.6 98.0 98.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 12 4 ALNNLLTEEEDYQGL ALNHLLTEEEDYQGL NNalign 27348.7 23702.7 0.867 NNalign 98.0 96.0 30 0.1 NA NA NA NA NA NA 27348.7 23702.7 0.867 98.0 96.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.7000000000000004 0.7857142857142856 False False False 0 False 0 23702.7 27348.7 96.0 98.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 7 10, 11, 12, 13, 14, 15 TGGGGRSAGSTGQGS TGGGGRSAGQHWARL NNalign 27429.0 8670.5 0.316 NNalign 98.0 79.0 142 0.768 NA NA NA NA NA NA 27429.0 8670.5 0.316 98.0 79.0 NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 8670.5 27429.0 79.0 98.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 16 NA STGQGSGEKAGCPWS NA NNalign 27683.6 NA NA NNalign 98.0 NA 142 0.768 NA NA NA NA NA NA 27683.6 NA NA 98.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 NA 27683.6 NA 98.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-DRB1*11:01 15 13 3 LNNLLTEEEDYQGLR LNHLLTEEEDYQGLR NNalign 28053.3 25810.8 0.92 NNalign 98.0 97.0 30 0.1 NA NA NA NA NA NA 28053.3 25810.8 0.92 98.0 97.0 NA NA NA NA NA NA NA NA 7.CLTCL1.ENST00000263200.10.missense.1469H/N -1.8428571428571432 0.02857142857142847 False False False 0 False 0 25810.8 28053.3 97.0 98.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 14 2 PARPPQQPVPTELSL PPRPPQQPVPTELSL NNalign 28397.5 28540.4 1.005 NNalign 98.0 98.0 245 0.486 NA NA NA NA NA NA 28397.5 28540.4 1.005 98.0 98.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A 0.7428571428571429 0.7428571428571429 False False False 0 False 0 28540.4 28397.5 98.0 98.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 11 5 RPGSAPTTVIYEDNQ RPGSSPTTVIYEDNQ NNalign 28463.3 29759.2 1.046 NNalign 98.0 99.0 7 0.571 NA NA NA NA NA NA 28463.3 29759.2 1.046 98.0 99.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.942857142857143 0.9571428571428572 False False False 0 False 0 29759.2 28463.3 99.0 98.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 7 9 EERTEASGYESRVEP EERTEASGSESRVEP NNalign 28524.3 32591.3 1.143 NNalign 98.0 99.0 116 0.043 NA NA NA NA NA NA 28524.3 32591.3 1.143 98.0 99.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.5714285714285712 -1.0142857142857145 True False True 0 False 0 32591.3 28524.3 99.0 98.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 10 NA GGRSAGSTGQGSGEK NA NNalign 28947.5 NA NA NNalign 99.0 NA 142 0.768 NA NA NA NA NA NA 28947.5 NA NA 99.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.842857142857143 -0.6285714285714287 False False False 0 False 0 NA 28947.5 NA 99.0 -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-DRB1*11:01 15 8 8 ERTEASGYESRVEPP ERTEASGSESRVEPP NNalign 29067.1 34344.7 1.182 NNalign 99.0 100.0 116 0.043 NA NA NA NA NA NA 29067.1 34344.7 1.182 99.0 100.0 NA NA NA NA NA NA NA NA 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.6142857142857143 -1.0142857142857145 True False True 0 False 0 34344.7 29067.1 100.0 99.0 -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-DRB1*11:01 15 5 12, 13, 14, 15 DPASAAAAAAAVIPT DPASAAAAAAAAAAA NNalign 29089.7 25855.5 0.889 NNalign 99.0 97.0 128 0.977 NA NA NA NA NA NA 29089.7 25855.5 0.889 99.0 97.0 NA NA NA NA NA NA NA NA 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 1.6857142857142862 2.5285714285714285 False False False 0 False 0 25855.5 29089.7 97.0 99.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 6 11, 12, 13, 14, 15 DTGGGGRSAGSTGQG DTGGGGRSAGQHWAR NNalign 29181.1 11523.6 0.395 NNalign 99.0 85.0 142 0.768 NA NA NA NA NA NA 29181.1 11523.6 0.395 99.0 85.0 NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6285714285714287 -0.6285714285714287 False False False 0 False 0 11523.6 29181.1 85.0 99.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 4 13, 14, 15 KEDTGGGGRSAGSTG KEDTGGGGRSAGQHW NNalign 29708.4 24748.1 0.833 NNalign 99.0 97.0 142 0.768 NA NA NA NA NA NA 29708.4 24748.1 0.833 99.0 97.0 NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8285714285714286 -0.7285714285714285 False False False 0 False 0 24748.1 29708.4 97.0 99.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 10 6 QRPGSAPTTVIYEDN QRPGSSPTTVIYEDN NNalign 29717.7 30232.7 1.017 NNalign 99.0 99.0 7 0.571 NA NA NA NA NA NA 29717.7 30232.7 1.017 99.0 99.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5428571428571428 0.9571428571428572 True False False 0 False 0 30232.7 29717.7 99.0 99.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 9 7 QQRPGSAPTTVIYED QQRPGSSPTTVIYED NNalign 30035.1 30546.1 1.017 NNalign 99.0 99.0 7 0.571 NA NA NA NA NA NA 30035.1 30546.1 1.017 99.0 99.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.14285714285714274 0.9571428571428572 True False False 0 False 0 30546.1 30035.1 99.0 99.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 5 12, 13, 14, 15 EDTGGGGRSAGSTGQ EDTGGGGRSAGQHWA NNalign 30368.1 18185.9 0.599 NNalign 99.0 93.0 142 0.768 NA NA NA NA NA NA 30368.1 18185.9 0.599 99.0 93.0 NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6857142857142857 -0.6857142857142857 True False False 0 False 0 18185.9 30368.1 93.0 99.0 -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-DRB1*11:01 15 2 15 VQPDPASAAAAAAAV VQPDPASAAAAAAAA NNalign 30739.0 30030.0 0.977 NNalign 99.0 99.0 128 0.977 NA NA NA NA NA NA 30739.0 30030.0 0.977 99.0 99.0 NA NA NA NA NA NA NA NA 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.142857142857143 2.142857142857143 False False False 0 False 0 30030.0 30739.0 99.0 99.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 11 NA GRSAGSTGQGSGEKA NA NNalign 31047.9 NA NA NNalign 99.0 NA 142 0.768 NA NA NA NA NA NA 31047.9 NA NA 99.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.5285714285714287 -0.6285714285714287 False False False 0 False 0 NA 31047.9 NA 99.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 10 6 VSPEPARPPQQPVPT VSPEPPRPPQQPVPT NNalign 31268.7 36605.8 1.171 NNalign 99.0 100.0 245 0.486 NA NA NA NA NA NA 31268.7 36605.8 1.171 99.0 100.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -1.1857142857142855 -0.8571428571428571 False False False 0 False 0 36605.8 31268.7 100.0 99.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 15 NA GSTGQGSGEKAGCPW NA NNalign 31274.8 NA NA NNalign 99.0 NA 142 0.768 NA NA NA NA NA NA 31274.8 NA NA 99.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.8571428571428574 -0.6714285714285715 False False False 1 False 0 NA 31274.8 NA 99.0 -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-DRB1*11:01 15 4 13, 14, 15 PDPASAAAAAAAVIP PDPASAAAAAAAAAA NNalign 31671.2 27961.8 0.883 NNalign 99.0 98.0 128 0.977 NA NA NA NA NA NA 31671.2 27961.8 0.883 99.0 98.0 NA NA NA NA NA NA NA NA 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.042857142857143 2.5285714285714285 False False True 0 False 0 27961.8 31671.2 98.0 99.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 13 3 EPARPPQQPVPTELS EPPRPPQQPVPTELS NNalign 31916.4 33420.2 1.047 NNalign 99.0 100.0 245 0.486 NA NA NA NA NA NA 31916.4 33420.2 1.047 99.0 100.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -0.02857142857142863 -0.02857142857142863 True False False 0 False 0 33420.2 31916.4 100.0 99.0 -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-DRB1*11:01 15 3 14, 15 QPDPASAAAAAAAVI QPDPASAAAAAAAAA NNalign 32380.5 30290.0 0.935 NNalign 99.0 99.0 128 0.977 NA NA NA NA NA NA 32380.5 30290.0 0.935 99.0 99.0 NA NA NA NA NA NA NA NA 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 2.5285714285714285 2.5285714285714285 True False False 0 False 0 30290.0 32380.5 99.0 99.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 12 NA RSAGSTGQGSGEKAG NA NNalign 32892.1 NA NA NNalign 99.0 NA 142 0.768 NA NA NA NA NA NA 32892.1 NA NA 99.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.0857142857142859 -0.6285714285714287 False False False 0 False 0 NA 32892.1 NA 99.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 13 NA SAGSTGQGSGEKAGC NA NNalign 34437.3 NA NA NNalign 100.0 NA 142 0.768 NA NA NA NA NA NA 34437.3 NA NA 100.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.6714285714285715 -0.6285714285714287 False True False 1 False 0 NA 34437.3 NA 100.0 -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 14 NA AGSTGQGSGEKAGCP NA NNalign 35436.7 NA NA NNalign 100.0 NA 142 0.768 NA NA NA NA NA NA 35436.7 NA NA 100.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.7857142857142857 -0.6285714285714287 False False True 1 False 0 NA 35436.7 NA 100.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 12 4 PEPARPPQQPVPTEL PEPPRPPQQPVPTEL NNalign 37381.9 40060.1 1.072 NNalign 100.0 100.0 245 0.486 NA NA NA NA NA NA 37381.9 40060.1 1.072 100.0 100.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -0.4142857142857142 -0.4142857142857142 False False False 0 False 0 40060.1 37381.9 100.0 100.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 11 5 SPEPARPPQQPVPTE SPEPPRPPQQPVPTE NNalign 37494.9 41590.4 1.109 NNalign 100.0 100.0 245 0.486 NA NA NA NA NA NA 37494.9 41590.4 1.109 100.0 100.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -1.457142857142857 -1.1857142857142855 False False False 0 False 0 41590.4 37494.9 100.0 100.0 +Chromosome Start Stop Reference Variant Transcript Transcript Support Level Transcript Length Canonical MANE Select Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Mutation Protein Position Gene Name HGVSc HGVSp HLA Allele Peptide Length Sub-peptide Position Mutation Position MT Epitope Seq WT Epitope Seq Best MT IC50 Score Method Best MT IC50 Score Corresponding WT IC50 Score Corresponding Fold Change Best MT Percentile Method Best MT Percentile Corresponding WT Percentile Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Median MT IC50 Score Median WT IC50 Score Median Fold Change Median MT Percentile Median WT Percentile NetMHC WT IC50 Score NetMHC MT IC50 Score NetMHC WT Percentile NetMHC MT Percentile PickPocket WT IC50 Score PickPocket MT IC50 Score PickPocket WT Percentile PickPocket MT Percentile Index Gene of Interest cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 2 9 ATLSRTLLL ATLSRTLLA PickPocket 2122.61 3272.12 1.542 NetMHC 0.12 5.1 76 0.158 NA NA NA NA NA NA 3816.925 14131.865 3.702 0.51 3.8 24991.61 5511.24 5.1 0.12 3272.12 2122.61 2.5 0.9 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.3142857142857143 1.3142857142857143 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 6 6 LLPLLPLLL LLPLLLLLL PickPocket 2551.25 3099.81 1.215 NetMHC 0.17 0.33 101 0.891 NA NA NA NA NA NA 4721.43 6167.26 1.306 0.785 1.265 9234.71 6891.61 0.33 0.17 3099.81 2551.25 2.2 1.4 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 5 7 PLLPLLPLL PLLPLLLLL NetMHC 8291.82 12130.52 1.463 NetMHC 0.27 0.61 101 0.891 NA NA NA NA NA NA 10139.345 14005.785 1.381 16.135 21.805 12130.52 8291.82 0.61 0.27 15881.05 11986.87 43.0 32.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 4 6 QRPGSAPTT QRPGSSPTT PickPocket 1362.11 1517.76 1.114 PickPocket 0.3 0.3 7 0.571 NA NA NA NA NA NA 6537.82 9406.765 1.439 0.435 1.05 17295.77 11713.53 1.8 0.57 1517.76 1362.11 0.3 0.3 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.5714285714285714 -0.5714285714285714 True False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 9 1 ARPPQQPVP PRPPQQPVP PickPocket 1654.99 4242.33 2.563 PickPocket 0.4 4.8 245 0.486 NA NA NA NA NA NA 6693.895 10556.225 1.577 0.485 3.2 16870.12 11732.8 1.6 0.57 4242.33 1654.99 4.8 0.4 15.GGA1.ENST00000343632.4.missense.484P/A False -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 8 1, 3, 4 PLLPLLLLL LLPLLLLLL NetMHC 12130.52 9234.71 0.761 NetMHC 0.61 0.33 101 0.891 NA NA NA NA NA NA 14005.785 6167.26 0.44 21.805 1.265 9234.71 12130.52 0.33 0.61 3099.81 15881.05 2.2 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 3.028571428571429 3.028571428571429 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 9 1 YLSDRCKIL CLSDRCKIL PickPocket 3491.59 5099.03 1.46 NetMHC 1.7 1.5 92 0.043 NA NA NA NA NA NA 10368.825 10737.38 1.036 2.35 4.25 16375.73 17246.06 1.5 1.7 5099.03 3491.59 7.0 3.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.27142857142857163 -0.27142857142857146 False False False 1 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 6 4 PEPARPPQQ PEPPRPPQQ PickPocket 2873.7 2812.19 0.979 PickPocket 1.8 1.7 245 0.486 NA NA NA NA NA NA 10491.195 7573.6 0.722 1.9 1.17 12335.01 18108.69 0.64 2.0 2812.19 2873.7 1.7 1.8 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -1.7999999999999996 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 5 5 KFNPQTDYL KFNPETDYL PickPocket 12117.27 14722.66 1.215 NetMHC 2.1 2.4 136 0.25 NA NA NA NA NA NA 15232.4 16891.63 1.109 17.05 21.2 19060.6 18347.53 2.4 2.1 14722.66 12117.27 40.0 32.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.4714285714285715 -1.4714285714285715 False False False 0 False 1 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 1 9 VLCQRAKVE VLCQRAKVA PickPocket 7860.43 8758.62 1.114 NetMHC 2.5 2.8 113 0.044 NA NA NA NA NA NA 13711.555 14502.285 1.058 10.25 11.9 20245.95 19562.68 2.8 2.5 8758.62 7860.43 21.0 18.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.9857142857142857 0.0571428571428572 False False False 1 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 9 1 IYGSGGYAL TYGSGGYAL PickPocket 7945.94 9972.95 1.255 NetMHC 2.5 4.1 120 0.233 NA NA NA NA NA NA 13754.31 16702.035 1.214 10.25 14.55 23431.12 19562.68 4.1 2.5 9972.95 7945.94 25.0 18.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.32857142857142857 0.32857142857142857 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 3 7 VNEALNNLL VNEALNHLL PickPocket 13070.67 15208.39 1.164 NetMHC 3.0 1.8 30 0.1 NA NA NA NA NA NA 17059.365 16297.11 0.955 19.0 21.4 17385.83 21048.06 1.8 3.0 15208.39 13070.67 41.0 35.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.3857142857142856 0.3857142857142856 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 7 3 LVRSRTYDM LVHSRTYDM PickPocket 4625.9 6610.93 1.429 NetMHC 3.2 3.4 210 0.686 NA NA NA NA NA NA 12986.865 14203.32 1.094 4.45 8.2 21795.71 21347.83 3.4 3.2 6610.93 4625.9 13.0 5.7 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.9142857142857144 -0.5428571428571428 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 1 9 ALGWEFLAF ALGWEFLAS PickPocket 6682.85 8950.22 1.339 NetMHC 4.1 28.0 171 0.959 NA NA NA NA NA NA 14995.67 23104.49 1.541 8.55 24.5 37258.76 23308.49 28.0 4.1 8950.22 6682.85 21.0 13.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.9142857142857143 1.0571428571428572 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 6 4 IGKHGGVSL IGKPGGVSL PickPocket 9447.76 7945.94 0.841 NetMHC 6.9 1.3 140 0.179 NA NA NA NA NA NA 18405.335 11610.23 0.631 14.95 9.65 15274.52 27362.91 1.3 6.9 7945.94 9447.76 18.0 23.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.10000000000000002 0.05714285714285713 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 7 3 GSAPTTVIY GSSPTTVIY PickPocket 8032.38 10414.04 1.297 NetMHC 6.9 12.0 7 0.571 NA NA NA NA NA NA 17734.85 20382.87 1.149 12.45 19.5 30351.7 27437.32 12.0 6.9 10414.04 8032.38 27.0 18.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.8857142857142858 0.9571428571428572 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 4 6 VSPEPARPP VSPEPPRPP PickPocket 7692.16 8297.38 1.079 NetMHC 7.2 19.0 245 0.486 NA NA NA NA NA NA 17719.675 21359.715 1.205 12.1 19.0 34422.05 27747.19 19.0 7.2 8297.38 7692.16 19.0 17.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.7999999999999996 -0.8571428571428571 False False True 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 2 8 AVRPLELVY AVRPLELAY PickPocket 9245.51 10414.04 1.126 NetMHC 7.4 18.0 113 0.053 NA NA NA NA NA NA 18558.34 22246.465 1.199 14.7 22.5 34078.89 27871.17 18.0 7.4 10414.04 9245.51 27.0 22.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.1285714285714286 0.9142857142857144 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 1 9 VSLFGALVR VSLFGALVH PickPocket 6330.92 5681.68 0.897 NetMHC 8.2 7.3 210 0.686 NA NA NA NA NA NA 17492.43 16741.485 0.957 10.1 8.05 27801.29 28653.94 7.3 8.2 5681.68 6330.92 8.8 12.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False 1.6428571428571428 2.1714285714285713 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 7 5, 9 LPLLPLLLL LPLLLLLLG PickPocket 16946.23 38565.12 2.276 NetMHC 8.8 60.0 101 0.891 NA NA NA NA NA NA 23057.685 40666.925 1.764 27.4 70.5 42768.73 29169.14 60.0 8.8 38565.12 16946.23 81.0 46.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 3.028571428571429 3.028571428571429 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 8 2 NLFNCECDL NPFNCECDL PickPocket 23444.56 50000.0 2.133 NetMHC 9.0 20.0 303 0.135 NA NA NA NA NA NA 26403.425 42358.58 1.604 34.5 54.0 34717.16 29362.29 20.0 9.0 50000.0 23444.56 88.0 60.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 True 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 4 6 RPLELVYCL RPLELAYCL PickPocket 26985.39 25017.04 0.927 NetMHC 9.4 3.4 113 0.053 NA NA NA NA NA NA 28357.175 23403.545 0.825 37.7 33.2 21790.05 29728.96 3.4 9.4 25017.04 26985.39 63.0 66.0 6.USP18.ENST00000215794.7.missense.124A/V False 1.9000000000000001 1.9000000000000001 False False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 1 9 YQPCDDMDY YQPCDDMDC PickPocket 1864.16 1804.62 0.968 PickPocket 0.6 0.6 92 0.043 NA NA NA NA NA NA 15927.085 16858.635 1.058 5.2 7.3 31912.65 29990.01 14.0 9.8 1804.62 1864.16 0.6 0.6 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 3 8 TLSRTLLLA TLSRTLLAA PickPocket 7287.08 8664.37 1.189 NetMHC 12.0 25.0 76 0.158 NA NA NA NA NA NA 18767.43 22490.125 1.198 14.0 22.5 36315.88 30247.78 25.0 12.0 8664.37 7287.08 20.0 16.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.0285714285714285 1.3142857142857143 False False False 0 False 0 +22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 Not Run Not Run protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-E*01:01 9 9 9 NMSSFKLKQ NMSSFKLKE PickPocket 3890.57 3848.7 0.989 PickPocket 4.0 3.9 117 0.496 NA NA NA NA NA NA 17113.26 17432.18 1.019 8.0 8.45 31015.66 30335.95 13.0 12.0 3848.7 3890.57 3.9 4.0 14.LGALS2.ENST00000215886.4.missense.132E/Q False -0.9000000000000001 -0.07142857142857155 False False False 0 True 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 9 1 EMSHFEPNE AMSHFEPNE PickPocket 3932.89 2443.19 0.621 PickPocket 4.2 1.3 113 0.044 NA NA NA NA NA NA 17166.29 15315.03 0.892 8.1 4.5 28186.87 30399.69 7.7 12.0 2443.19 3932.89 1.3 4.2 18.ACO2.ENST00000216254.4.missense.33A/E False -1.9000000000000001 -1.1285714285714286 True False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 8 2 AFTRLTSEL ASTRLTSEL NetMHC 30541.45 30699.15 1.005 NetMHC 12.0 12.0 171 0.959 NA NA NA NA NA NA 33736.555 33033.27 0.979 45.5 45.0 30699.15 30541.45 12.0 12.0 35367.39 36931.66 78.0 79.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.3714285714285715 0.24285714285714272 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 6 4 FNPQTDYLT FNPETDYLT PickPocket 2551.25 2416.9 0.947 PickPocket 1.4 1.2 136 0.25 NA NA NA NA NA NA 16712.305 17461.505 1.045 6.7 8.1 32506.11 30873.36 15.0 12.0 2416.9 2551.25 1.2 1.4 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.0714285714285716 -1.0714285714285716 False False False 0 False 1 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 1 9 MVCELAGNL MVCELAGNP PickPocket 26985.39 42509.45 1.575 NetMHC 14.0 60.0 303 0.135 NA NA NA NA NA NA 29477.705 42658.77 1.447 40.0 72.0 42808.09 31970.02 60.0 14.0 42509.45 26985.39 84.0 66.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6428571428571427 1.4714285714285713 False False False 1 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 9 2, 3 LLPLLLLLG LPLLLLLLG PickPocket 4676.23 38565.12 8.247 PickPocket 5.9 81.0 101 0.891 NA NA NA NA NA NA 18328.65 40666.925 2.219 9.95 70.5 42768.73 31981.07 60.0 14.0 38565.12 4676.23 81.0 5.9 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.4285714285714293 3.028571428571429 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 3 7 QQRPGSAPT QQRPGSSPT PickPocket 15044.73 27575.71 1.833 NetMHC 15.0 18.0 7 0.571 NA NA NA NA NA NA 23844.505 30735.185 1.289 27.5 42.5 33894.66 32644.28 18.0 15.0 27575.71 15044.73 67.0 40.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.1142857142857143 -1.1142857142857143 True False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 5 5 SPEPARPPQ SPEPPRPPQ PickPocket 8758.62 10414.04 1.189 NetMHC 16.0 18.0 245 0.486 NA NA NA NA NA NA 20979.65 22234.49 1.06 18.5 22.5 34054.94 33200.68 18.0 16.0 10414.04 8758.62 27.0 21.0 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -1.6857142857142855 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 20 NA GCPWSGTGQ NA PickPocket 10527.33 NA NA NetMHC 17.0 NA 142 0.768 NA NA NA NA NA NA 21882.695 NA NA 22.0 NA NA 33238.06 NA 17.0 NA 10527.33 NA 27.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.1857142857142857 -0.32857142857142857 False False False 1 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 3 7 RTEASGYES RTEASGSES PickPocket 7366.35 21500.59 2.919 PickPocket 16.0 56.0 116 0.043 NA NA NA NA NA NA 20386.21 29661.16 1.455 16.5 43.0 37821.73 33406.07 30.0 17.0 21500.59 7366.35 56.0 16.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.2142857142857142 -1.2 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 3 7 VRPLELVYC VRPLELAYC PickPocket 8387.64 12930.01 1.542 NetMHC 17.0 22.0 113 0.053 NA NA NA NA NA NA 21020.02 24267.335 1.154 18.0 28.5 35604.66 33652.4 22.0 17.0 12930.01 8387.64 35.0 19.0 6.USP18.ENST00000215794.7.missense.124A/V False 1.1285714285714286 1.1285714285714286 False True False 1 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 8 2 SAPTTVIYE SSPTTVIYE PickPocket 4429.97 2077.17 0.469 PickPocket 5.2 0.8 7 0.571 NA NA NA NA NA NA 19201.975 18554.51 0.966 11.6 10.9 35031.85 33973.98 21.0 18.0 2077.17 4429.97 0.8 5.2 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.12857142857142861 0.9571428571428572 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 2 8 QPCDDMDYL QPCDDMDCL NetMHC 34131.66 34638.75 1.015 NetMHC 18.0 20.0 92 0.043 NA NA NA NA NA NA 42065.83 42319.375 1.006 53.0 54.0 34638.75 34131.66 20.0 18.0 50000.0 50000.0 88.0 88.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.5142857142857142 -0.5142857142857142 True False False 1 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 2 8 VCELAGNLF VCELAGNPF PickPocket 17130.58 20149.14 1.176 NetMHC 19.0 32.0 303 0.135 NA NA NA NA NA NA 25730.19 29224.695 1.136 32.5 42.5 38300.25 34329.8 32.0 19.0 20149.14 17130.58 53.0 46.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6857142857142856 0.7000000000000001 False False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 4 6 WEFLAFTRL WEFLASTRL NetMHC 35077.0 34584.44 0.986 NetMHC 21.0 20.0 171 0.959 NA NA NA NA NA NA 39258.18 37210.95 0.948 53.0 51.0 34584.44 35077.0 20.0 21.0 39837.46 43439.36 82.0 85.0 22.PANX2.ENST00000395842.2.missense.147S/F False 1.4000000000000001 1.4000000000000001 False False False 0 False 0 +4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 Not Run Not Run protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-E*01:01 9 2 9 SAAAAAAAV SAAAAAAAA PickPocket 21040.32 21040.32 1.0 NetMHC 21.0 30.0 128 0.977 NA NA NA NA NA NA 28125.2 29506.67 1.049 38.0 42.5 37973.02 35210.08 30.0 21.0 21040.32 21040.32 55.0 55.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A False 2.142857142857143 2.142857142857143 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 4 8 PPLLPLLPL PPLLPLLLL NetMHC 35483.9 31563.06 0.89 NetMHC 22.0 14.0 101 0.891 NA NA NA NA NA NA 42741.95 37737.485 0.883 55.0 49.5 31563.06 35483.9 14.0 22.0 43911.91 50000.0 85.0 88.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 4 6 ELAGNLFNC ELAGNPFNC PickPocket 12117.27 9972.95 0.823 NetMHC 23.0 17.0 303 0.135 NA NA NA NA NA NA 23882.17 21748.705 0.911 27.5 21.0 33524.46 35647.07 17.0 23.0 9972.95 12117.27 25.0 32.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.5 0.6857142857142856 True True False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 5 5 EFLAFTRLT EFLASTRLT NetMHC 35694.53 31850.89 0.892 NetMHC 23.0 14.0 171 0.959 NA NA NA NA NA NA 36114.375 25891.6 0.717 51.0 33.5 31850.89 35694.53 14.0 23.0 19932.31 36534.22 53.0 79.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.8999999999999997 1.4000000000000001 True False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 6 4 DMDYLSDRC DMDCLSDRC PickPocket 20813.9 18478.42 0.888 NetMHC 24.0 26.0 92 0.043 NA NA NA NA NA NA 28413.27 27614.355 0.972 39.5 37.5 36750.29 36012.64 26.0 24.0 18478.42 20813.9 49.0 55.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.042857142857143 -0.9857142857142857 False True False 1 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 3 9 PPPLLPLLP PPPLLPLLL PickPocket 29108.61 18478.42 0.635 NetMHC 24.0 2.7 101 0.891 NA NA NA NA NA NA 32658.89 19267.885 0.59 46.5 25.85 20057.35 36209.17 2.7 24.0 18478.42 29108.61 49.0 69.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 1.4857142857142858 1.4857142857142858 False False True 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 7 3 WTHSRDPEG WTRSRDPEG PickPocket 2523.8 1765.99 0.7 PickPocket 1.4 0.5 56 0.071 NA NA NA NA NA NA 19369.23 18322.905 0.946 12.7 10.25 34879.82 36214.66 20.0 24.0 1765.99 2523.8 0.5 1.4 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5 -2.1714285714285717 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 8 1 LLLAAAGGS TLLAAAGGS PickPocket 19088.05 20368.33 1.067 NetMHC 24.0 19.0 76 0.158 NA NA NA NA NA NA 27654.285 27433.97 0.992 37.5 36.0 34499.61 36220.52 19.0 24.0 20368.33 19088.05 53.0 51.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.0857142857142856 2.342857142857143 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 9 1 TQKRNSRRQ AQKRNSRRQ PickPocket 17695.75 16763.86 0.947 NetMHC 25.0 28.0 96 0.042 NA NA NA NA NA NA 27006.015 27051.47 1.002 36.0 36.5 37339.08 36316.28 28.0 25.0 16763.86 17695.75 45.0 47.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.6000000000000005 -3.0571428571428574 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 3 7 TVSPEPARP TVSPEPPRP PickPocket 33144.32 7692.16 0.232 NetMHC 26.0 5.6 245 0.486 NA NA NA NA NA NA 34982.33 16684.78 0.477 50.5 11.3 25677.4 36820.34 5.6 26.0 7692.16 33144.32 17.0 75.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.6857142857142855 -0.31428571428571433 False False True 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 6 NA RSAGSTGQG NA PickPocket 8664.37 NA NA PickPocket 20.0 NA 142 0.768 NA NA NA NA NA NA 23011.42 NA NA 24.0 NA NA 37358.47 NA 28.0 NA 8664.37 NA 20.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6285714285714287 -0.6285714285714287 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 3 7 CQRAKVEMS CQRAKVAMS PickPocket 4778.52 6062.77 1.269 PickPocket 6.2 9.9 113 0.044 NA NA NA NA NA NA 21085.485 22085.815 1.047 17.1 20.45 38108.86 37392.45 31.0 28.0 6062.77 4778.52 9.9 6.2 18.ACO2.ENST00000216254.4.missense.33A/E False -0.6857142857142857 -0.6857142857142857 True False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 6 4 FLAFTRLTS FLASTRLTS PickPocket 3343.7 3202.08 0.958 PickPocket 2.7 2.4 171 0.959 NA NA NA NA NA NA 20419.935 19400.67 0.95 15.85 12.2 35599.26 37496.17 22.0 29.0 3202.08 3343.7 2.4 2.7 22.PANX2.ENST00000395842.2.missense.147S/F False 0.24285714285714272 1.4000000000000001 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 8 2 PARPPQQPV PPRPPQQPV NetMHC 37726.09 38390.68 1.018 NetMHC 29.0 32.0 245 0.486 NA NA NA NA NA NA 43863.045 44195.34 1.008 58.5 60.0 38390.68 37726.09 32.0 29.0 50000.0 50000.0 88.0 88.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.7285714285714289 -1.7285714285714289 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 6 4 PGSAPTTVI PGSSPTTVI NetMHC 37748.53 39718.24 1.052 NetMHC 29.0 39.0 7 0.571 NA NA NA NA NA NA 43874.265 44859.12 1.022 58.5 63.5 39718.24 37748.53 39.0 29.0 50000.0 50000.0 88.0 88.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.9571428571428572 0.9571428571428572 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 16 NA GEKAGCPWS NA PickPocket 8119.76 NA NA PickPocket 18.0 NA 142 0.768 NA NA NA NA NA NA 23066.335 NA NA 24.5 NA NA 38012.91 NA 31.0 NA 8119.76 NA 18.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 9 1 QDAAQGIAK EDAAQGIAK PickPocket 10191.11 12790.86 1.255 PickPocket 26.0 34.0 22 0.5 NA NA NA NA NA NA 24120.93 26133.085 1.083 28.5 35.5 39475.31 38050.75 37.0 31.0 12790.86 10191.11 34.0 26.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False 0.3 0.35714285714285715 True False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 4 6 KEEEKTQEV KEEEKPQEV PickPocket 13070.67 13797.25 1.056 NetMHC 31.0 47.0 185 0.038 NA NA NA NA NA NA 25606.68 27404.275 1.07 33.0 42.0 41011.3 38142.69 47.0 31.0 13797.25 13070.67 37.0 35.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.0571428571428574 -2.0571428571428574 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 3 7 CELAGNLFN CELAGNPFN PickPocket 10527.33 7945.94 0.755 PickPocket 27.0 18.0 303 0.135 NA NA NA NA NA NA 24351.52 21388.74 0.878 29.0 19.0 34831.54 38175.71 20.0 31.0 7945.94 10527.33 18.0 27.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6857142857142856 0.6857142857142856 True False False 1 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 4 6 NEALNNLLT NEALNHLLT PickPocket 15044.73 15208.39 1.011 NetMHC 32.0 29.0 30 0.1 NA NA NA NA NA NA 26687.205 26477.45 0.992 36.0 35.0 37746.51 38329.68 29.0 32.0 15208.39 15044.73 41.0 40.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.7857142857142856 0.7857142857142856 False False False 0 True 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 7 3 KVEMSHFEP KVAMSHFEP PickPocket 9550.53 7527.49 0.788 PickPocket 24.0 16.0 113 0.044 NA NA NA NA NA NA 24092.905 21699.485 0.901 28.5 19.5 35871.48 38635.28 23.0 33.0 7527.49 9550.53 16.0 24.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.1285714285714286 -0.3000000000000001 False False True 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 3 7 VTISCTGSS VTISCTRSS NetMHC 38650.33 36991.66 0.957 NetMHC 33.0 27.0 5 1.0 NA NA NA NA NA NA 40351.155 34366.06 0.852 58.5 50.0 36991.66 38650.33 27.0 33.0 31740.46 42051.98 73.0 84.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.5 1.2285714285714284 False False False 1 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 2 8 SVNEALNNL SVNEALNHL PickPocket 20813.9 20813.9 1.0 NetMHC 33.0 32.0 30 0.1 NA NA NA NA NA NA 29741.95 29611.85 0.996 44.0 43.5 38409.8 38670.0 32.0 33.0 20813.9 20813.9 55.0 55.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 6 4 ALVRSRTYD ALVHSRTYD PickPocket 25564.3 23444.56 0.917 NetMHC 33.0 41.0 210 0.686 NA NA NA NA NA NA 32120.92 31774.645 0.989 48.5 50.5 40104.73 38677.54 41.0 33.0 23444.56 25564.3 60.0 64.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.5857142857142856 -0.09999999999999987 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 6 4 IANQDAAQG IANEDAAQG NetMHC 38788.59 39240.25 1.012 NetMHC 34.0 36.0 22 0.5 NA NA NA NA NA NA 42570.76 41576.08 0.977 60.0 60.5 39240.25 38788.59 36.0 34.0 43911.91 46352.93 85.0 86.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.5428571428571427 -0.08571428571428576 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 8 2 VRSRTYDMD VHSRTYDMD PickPocket 23192.26 21040.32 0.907 NetMHC 34.0 31.0 210 0.686 NA NA NA NA NA NA 31044.845 29587.16 0.953 47.0 43.0 38134.0 38897.43 31.0 34.0 21040.32 23192.26 55.0 60.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.7714285714285716 -1.5857142857142856 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 9 1 YESRVEPPH SESRVEPPH PickPocket 8387.64 10757.62 1.283 PickPocket 19.0 28.0 116 0.043 NA NA NA NA NA NA 23762.22 24573.94 1.034 27.5 30.0 38390.26 39136.8 32.0 36.0 10757.62 8387.64 28.0 19.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.5714285714285714 -1.5714285714285712 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 8 2 NQDAAQGIA NEDAAQGIA PickPocket 18478.42 39837.46 2.156 NetMHC 36.0 46.0 22 0.5 NA NA NA NA NA NA 28851.06 40418.18 1.401 42.5 64.0 40998.9 39223.7 46.0 36.0 39837.46 18478.42 82.0 49.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False 0.35714285714285715 0.35714285714285715 False False False 0 True 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 7 3 ELVYCLQKC ELAYCLQKC PickPocket 32434.8 25289.19 0.78 NetMHC 37.0 26.0 113 0.053 NA NA NA NA NA NA 35878.97 30993.52 0.864 55.5 45.0 36697.85 39323.14 26.0 37.0 25289.19 32434.8 64.0 74.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.6142857142857141 0.8571428571428571 True True False 2 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 8 2 VEMSHFEPN VAMSHFEPN PickPocket 27575.71 34610.27 1.255 NetMHC 37.0 38.0 113 0.044 NA NA NA NA NA NA 33527.865 37089.41 1.106 52.0 57.5 39568.55 39480.02 38.0 37.0 34610.27 27575.71 77.0 67.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.1285714285714286 -0.3000000000000001 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 8 2 TTQKRNSRR TAQKRNSRR PickPocket 25017.04 42051.98 1.681 NetMHC 37.0 37.0 96 0.042 NA NA NA NA NA NA 32252.81 40701.4 1.262 50.0 60.5 39350.82 39488.58 37.0 37.0 42051.98 25017.04 84.0 63.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.6 -2.5142857142857147 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 7 1, 2 TLLLAAAGG RTLLAAAGG PickPocket 22695.78 19505.61 0.859 NetMHC 38.0 46.0 76 0.158 NA NA NA NA NA NA 31150.365 30217.01 0.97 48.5 49.0 40928.41 39604.95 46.0 38.0 19505.61 22695.78 52.0 59.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.742857142857143 2.342857142857143 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 3 7 GWEFLAFTR GWEFLASTR PickPocket 10527.33 45854.11 4.356 PickPocket 27.0 86.0 171 0.959 NA NA NA NA NA NA 25118.7 44690.015 1.779 33.0 76.5 43525.92 39710.07 67.0 39.0 45854.11 10527.33 86.0 27.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.35714285714285704 0.9142857142857143 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 19 NA AGCPWSGTG NA NetMHC 39974.77 NA NA NetMHC 40.0 NA 142 0.768 NA NA NA NA NA NA 41242.11 NA NA 62.0 NA NA 39974.77 NA 40.0 NA 42509.45 NA 84.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.3285714285714286 0.02857142857142855 False False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 2 8 LCQRAKVEM LCQRAKVAM PickPocket 10874.65 11857.88 1.09 PickPocket 28.0 31.0 113 0.044 NA NA NA NA NA NA 25452.185 26071.115 1.024 34.0 36.5 40284.35 40029.72 42.0 40.0 11857.88 10874.65 31.0 28.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.0714285714285712 0.0571428571428572 False False False 1 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 1 9 YYSYGLLHI YYSYGLLHT PickPocket 4727.1 4830.5 1.022 PickPocket 6.0 6.3 120 0.233 NA NA NA NA NA NA 22387.515 23381.725 1.044 23.0 29.65 41932.95 40047.93 53.0 40.0 4830.5 4727.1 6.3 6.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9142857142857143 0.9142857142857143 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 9 1 LFNCECDLF PFNCECDLF PickPocket 22695.78 50000.0 2.203 NetMHC 41.0 53.0 303 0.135 NA NA NA NA NA NA 31394.62 45933.37 1.463 50.0 70.5 41866.74 40093.46 53.0 41.0 50000.0 22695.78 88.0 59.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 7 3 ANQDAAQGI ANEDAAQGI PickPocket 8664.37 9972.95 1.151 PickPocket 20.0 25.0 22 0.5 NA NA NA NA NA NA 24392.79 25196.975 1.033 30.5 34.0 40421.0 40121.21 43.0 41.0 9972.95 8664.37 25.0 20.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 -0.4000000000000001 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 6 4 VWTHSRDPE VWTRSRDPE PickPocket 13947.35 15208.39 1.09 PickPocket 37.0 41.0 56 0.071 NA NA NA NA NA NA 27044.275 26957.82 0.997 39.0 37.5 38707.25 40141.2 34.0 41.0 15208.39 13947.35 41.0 37.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5428571428571423 -1.3428571428571427 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 1 9 KSVNEALNN KSVNEALNH PickPocket 5382.48 5441.03 1.011 PickPocket 8.0 8.1 30 0.1 NA NA NA NA NA NA 22783.995 22279.39 0.978 24.5 21.55 39117.75 40185.51 35.0 41.0 5441.03 5382.48 8.1 8.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6 -0.21428571428571427 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 9 1 RSRTYDMDV HSRTYDMDV PickPocket 6903.33 8387.64 1.215 PickPocket 14.0 19.0 210 0.686 NA NA NA NA NA NA 23600.815 25560.14 1.083 28.0 39.5 42732.64 40298.3 60.0 42.0 8387.64 6903.33 19.0 14.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 5 5 GALVRSRTY GALVHSRTY PickPocket 29745.37 50000.0 1.681 NetMHC 42.0 65.0 210 0.686 NA NA NA NA NA NA 35029.685 46655.615 1.332 56.0 76.5 43311.23 40314.0 65.0 42.0 50000.0 29745.37 88.0 70.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.5428571428571428 -0.05714285714285732 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 5 5 VVVTTQKRN VVVTAQKRN PickPocket 22451.54 19932.31 0.888 NetMHC 42.0 44.0 96 0.042 NA NA NA NA NA NA 31421.625 30315.325 0.965 50.0 48.5 40698.34 40391.71 44.0 42.0 19932.31 22451.54 53.0 58.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -1.8 0.5428571428571433 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 7 3 CTGSSGSIA CTRSSGSIA PickPocket 34610.27 24218.04 0.7 NetMHC 43.0 33.0 5 1.0 NA NA NA NA NA NA 37519.795 31364.06 0.836 60.0 47.5 38510.08 40429.32 33.0 43.0 24218.04 34610.27 62.0 77.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.4428571428571428 0.4428571428571428 True False False 1 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 1 9 KAVRPLELV KAVRPLELA PickPocket 32787.64 32787.64 1.0 NetMHC 43.0 57.0 113 0.053 NA NA NA NA NA NA 36648.095 37620.74 1.027 58.5 65.5 42453.84 40508.55 57.0 43.0 32787.64 32787.64 74.0 74.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.9142857142857144 0.9142857142857144 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 4 6 TEASGYESR TEASGSESR PickPocket 25564.3 22942.68 0.897 NetMHC 44.0 43.0 116 0.043 NA NA NA NA NA NA 33069.985 31694.97 0.958 54.0 51.0 40447.26 40575.67 43.0 44.0 22942.68 25564.3 59.0 64.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.3571428571428572 -1.2 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 5 5 RPGSAPTTV RPGSSPTTV NetMHC 40594.12 38806.21 0.956 NetMHC 44.0 34.0 7 0.571 NA NA NA NA NA NA 44238.16 41122.785 0.93 65.5 59.5 38806.21 40594.12 34.0 44.0 43439.36 47882.2 85.0 87.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.2571428571428571 0.2571428571428571 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 2 8 HTVSPEPAR HTVSPEPPR PickPocket 5210.57 5154.5 0.989 PickPocket 7.4 7.2 245 0.486 NA NA NA NA NA NA 22958.865 22465.835 0.979 25.7 23.1 39777.17 40707.16 39.0 44.0 5154.5 5210.57 7.2 7.4 15.GGA1.ENST00000343632.4.missense.484P/A False -0.8571428571428571 -0.31428571428571433 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 4 6 TVVVTTQKR TVVVTAQKR PickPocket 24747.82 24218.04 0.979 NetMHC 45.0 39.0 96 0.042 NA NA NA NA NA NA 32738.51 31990.935 0.977 54.0 50.5 39763.83 40729.2 39.0 45.0 24218.04 24747.82 62.0 63.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -0.7000000000000001 1.0000000000000002 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 2 8 GTLKFNPQT GTLKFNPET PickPocket 12930.01 13070.67 1.011 PickPocket 35.0 35.0 136 0.25 NA NA NA NA NA NA 26831.14 27035.22 1.008 40.0 40.5 40999.77 40732.27 46.0 45.0 13070.67 12930.01 35.0 35.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.942857142857143 -0.5000000000000001 False False False 0 False 1 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 3 7 TLKFNPQTD TLKFNPETD PickPocket 18082.85 17316.93 0.958 NetMHC 45.0 50.0 136 0.25 NA NA NA NA NA NA 29459.19 29409.41 0.998 46.5 48.5 41501.89 40835.53 50.0 45.0 17316.93 18082.85 47.0 48.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.9857142857142855 -0.942857142857143 False False False 0 False 1 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 7 3 NPQTDYLTG NPETDYLTG PickPocket 21970.92 25289.19 1.151 NetMHC 45.0 47.0 136 0.25 NA NA NA NA NA NA 31408.965 33193.335 1.057 51.0 55.5 41097.48 40847.01 47.0 45.0 25289.19 21970.92 64.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.9000000000000001 -0.9000000000000001 False False False 0 True 1 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 3 7 VQGIANQDA VQGIANEDA PickPocket 15208.39 14564.23 0.958 PickPocket 41.0 39.0 22 0.5 NA NA NA NA NA NA 28075.265 28087.465 1.0 43.5 45.0 41610.7 40942.14 51.0 46.0 14564.23 15208.39 39.0 41.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 -0.0571428571428572 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 21 NA CPWSGTGQH NA NetMHC 40983.8 NA NA NetMHC 46.0 NA 142 0.768 NA NA NA NA NA NA 45491.9 NA NA 67.0 NA NA 40983.8 NA 46.0 NA 50000.0 NA 88.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.4142857142857141 -0.3285714285714286 True False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 4 6 CDDMDYLSD CDDMDCLSD PickPocket 9759.45 8950.22 0.917 PickPocket 24.0 21.0 92 0.043 NA NA NA NA NA NA 25379.61 25069.26 0.988 35.0 34.5 41188.3 40999.77 48.0 46.0 8950.22 9759.45 21.0 24.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.9857142857142857 -0.5142857142857142 True False False 1 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 1 9 EERTEASGY EERTEASGS NetMHC 41033.07 42386.81 1.033 NetMHC 47.0 57.0 116 0.043 NA NA NA NA NA NA 45516.535 46193.405 1.015 67.5 72.5 42386.81 41033.07 57.0 47.0 50000.0 50000.0 88.0 88.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.342857142857143 -1.342857142857143 True False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 4 6 QRAKVEMSH QRAKVAMSH PickPocket 14564.23 12790.86 0.878 PickPocket 39.0 34.0 113 0.044 NA NA NA NA NA NA 27877.595 24624.24 0.883 43.5 29.5 36457.62 41190.96 25.0 48.0 12790.86 14564.23 34.0 39.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.5 -0.5 True False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 7 3 EPARPPQQP EPPRPPQQP NetMHC 41254.31 36882.54 0.894 NetMHC 48.0 26.0 245 0.486 NA NA NA NA NA NA 45627.155 33639.305 0.737 68.0 48.5 36882.54 41254.31 26.0 48.0 30396.07 50000.0 71.0 88.0 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -2.0714285714285716 True False True 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 6 4 ASGYESRVE ASGSESRVE PickPocket 24747.82 22209.93 0.897 NetMHC 48.0 47.0 116 0.043 NA NA NA NA NA NA 33019.82 31642.815 0.958 55.5 52.0 41075.7 41291.82 47.0 48.0 22209.93 24747.82 57.0 63.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.4000000000000001 -1.0142857142857145 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 8 2 THSRDPEGS TRSRDPEGS PickPocket 17130.58 18882.64 1.102 PickPocket 46.0 50.0 56 0.071 NA NA NA NA NA NA 29258.16 30370.17 1.038 47.5 51.5 41857.7 41385.74 53.0 49.0 18882.64 17130.58 50.0 46.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 7 3 VTTQKRNSR VTAQKRNSR PickPocket 18279.56 14722.66 0.805 NetMHC 49.0 37.0 96 0.042 NA NA NA NA NA NA 29838.925 27032.045 0.906 49.0 38.5 39341.43 41398.29 37.0 49.0 14722.66 18279.56 40.0 49.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.0571428571428574 -1.8 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 9 1 NLLTEEEDY HLLTEEEDY PickPocket 28795.36 18882.64 0.656 NetMHC 49.0 51.0 30 0.1 NA NA NA NA NA NA 35121.695 30253.42 0.861 59.0 50.5 41624.2 41448.03 51.0 49.0 18882.64 28795.36 50.0 69.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.742857142857143 -1.0142857142857145 False False False 0 True 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 5 5 LIGKHGGVS LIGKPGGVS PickPocket 25564.3 30396.07 1.189 NetMHC 50.0 54.0 140 0.179 NA NA NA NA NA NA 33518.955 36233.81 1.081 57.0 62.5 42071.55 41473.61 54.0 50.0 30396.07 25564.3 71.0 64.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.7000000000000001 0.05714285714285713 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 3 8, 9 GGGRSAGST GGGRSAGQH PickPocket 31740.46 29425.27 0.927 NetMHC 50.0 45.0 142 0.768 NA NA NA NA NA NA 36612.415 35130.625 0.96 61.5 57.5 40835.98 41484.37 45.0 50.0 29425.27 31740.46 70.0 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8285714285714286 -0.7285714285714286 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 5 5 RAKVEMSHF RAKVAMSHF NetMHC 41500.1 41442.2 0.999 NetMHC 50.0 49.0 113 0.044 NA NA NA NA NA NA 45750.05 41075.56 0.898 69.0 66.0 41442.2 41500.1 49.0 50.0 40708.92 50000.0 83.0 88.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.35714285714285715 -0.35714285714285715 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 17 NA EKAGCPWSG NA PickPocket 19088.05 NA NA NetMHC 50.0 NA 142 0.768 NA NA NA NA NA NA 30304.18 NA NA 50.5 NA NA 41520.31 NA 50.0 NA 19088.05 NA 51.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False 0.02857142857142855 0.02857142857142855 True False False 1 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 9 1 TQEVKVKEP PQEVKVKEP PickPocket 9346.08 22695.78 2.428 PickPocket 23.0 59.0 185 0.038 NA NA NA NA NA NA 25436.785 33041.96 1.299 36.5 62.5 43388.14 41527.49 66.0 50.0 22695.78 9346.08 59.0 23.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.1428571428571428 -1.0142857142857142 False False True 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 7 3 LAFTRLTSE LASTRLTSE NetMHC 41558.95 41511.32 0.999 NetMHC 50.0 50.0 171 0.959 NA NA NA NA NA NA 43215.725 36973.06 0.856 67.5 62.0 41511.32 41558.95 50.0 50.0 32434.8 44872.5 74.0 85.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.5142857142857143 0.8999999999999997 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 8 2 GYESRVEPP GSESRVEPP PickPocket 8208.09 8571.13 1.044 PickPocket 19.0 20.0 116 0.043 NA NA NA NA NA NA 24893.865 25226.19 1.013 34.5 36.5 41881.25 41579.64 53.0 50.0 8571.13 8208.09 20.0 19.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.6142857142857143 -1.4000000000000001 False False True 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 8 2 HIYGSGGYA HTYGSGGYA PickPocket 18478.42 25289.19 1.369 PickPocket 49.0 64.0 120 0.233 NA NA NA NA NA NA 30059.19 33821.28 1.125 50.0 60.5 42353.37 41639.96 57.0 51.0 25289.19 18478.42 64.0 49.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.39999999999999997 -0.014285714285714266 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 6 4 LELVYCLQK LELAYCLQK PickPocket 16946.23 13501.89 0.797 PickPocket 46.0 36.0 113 0.053 NA NA NA NA NA NA 29325.56 25763.355 0.879 48.5 33.5 38024.82 41704.89 31.0 51.0 13501.89 16946.23 36.0 46.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.7999999999999999 1.9000000000000001 False False False 1 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 5 5 PLELVYCLQ PLELAYCLQ NetMHC 41747.79 40906.72 0.98 NetMHC 52.0 46.0 113 0.053 NA NA NA NA NA NA 45873.895 39945.685 0.871 70.0 63.5 40906.72 41747.79 46.0 52.0 38984.65 50000.0 81.0 88.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.8571428571428571 1.9000000000000001 False False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 11 NA TGQGSGEKA NA PickPocket 11479.16 NA NA PickPocket 30.0 NA 142 0.768 NA NA NA NA NA NA 26614.605 NA NA 41.0 NA NA 41750.05 NA 52.0 NA 11479.16 NA 30.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.5285714285714287 -1.3857142857142857 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 4 6 DLIGKHGGV DLIGKPGGV PickPocket 36931.66 32787.64 0.888 NetMHC 52.0 54.0 140 0.179 NA NA NA NA NA NA 39372.5 37389.805 0.95 65.5 64.0 41991.97 41813.34 54.0 52.0 32787.64 36931.66 74.0 79.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.05714285714285713 0.05714285714285713 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 3 7 VKEEEKTQE VKEEEKPQE PickPocket 40270.83 6469.41 0.161 NetMHC 53.0 22.0 185 0.038 NA NA NA NA NA NA 41077.4 20994.9 0.511 67.5 17.5 35520.39 41883.97 22.0 53.0 6469.41 40270.83 13.0 82.0 12.NEFH.ENST00000310624.6.missense.830P/T False -3.1571428571428575 -2.1142857142857143 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 9 1 VYCLQKCNV AYCLQKCNV PickPocket 25289.19 25289.19 1.0 NetMHC 53.0 71.0 113 0.053 NA NA NA NA NA NA 33596.78 34586.065 1.029 58.5 67.5 43882.94 41904.37 71.0 53.0 25289.19 25289.19 64.0 64.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.3 0.6142857142857141 False False False 2 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 2 8 SLFGALVRS SLFGALVHS PickPocket 13070.67 13648.77 1.044 PickPocket 35.0 37.0 210 0.686 NA NA NA NA NA NA 27492.97 28347.33 1.031 44.0 50.0 43045.89 41915.27 63.0 53.0 13648.77 13070.67 37.0 35.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False 0.9857142857142857 2.1714285714285713 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 6 4 SCTGSSGSI SCTRSSGSI PickPocket 18882.64 23192.26 1.228 PickPocket 50.0 60.0 5 1.0 NA NA NA NA NA NA 30413.015 31845.155 1.047 51.5 51.5 40498.05 41943.39 43.0 53.0 23192.26 18882.64 60.0 50.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.08571428571428566 0.08571428571428566 False False False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 9 1 QTDYLTGTD ETDYLTGTD NetMHC 41972.45 42738.65 1.018 NetMHC 54.0 60.0 136 0.25 NA NA NA NA NA NA 45986.225 46369.325 1.008 71.0 74.0 42738.65 41972.45 60.0 54.0 50000.0 50000.0 88.0 88.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.9 -0.5 True False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 15 NA SGEKAGCPW NA PickPocket 19295.7 NA NA PickPocket 51.0 NA 142 0.768 NA NA NA NA NA NA 30648.155 NA NA 52.5 NA NA 42000.61 NA 54.0 NA 19295.7 NA 51.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8571428571428574 -0.6714285714285715 False False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 8 2 DYLSDRCKI DCLSDRCKI PickPocket 30396.07 40708.92 1.339 NetMHC 54.0 54.0 92 0.043 NA NA NA NA NA NA 36226.08 41400.25 1.143 62.5 68.5 42091.58 42056.09 54.0 54.0 40708.92 30396.07 83.0 71.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.27142857142857146 -0.27142857142857146 False False False 1 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 2 8 AVQGIANQD AVQGIANED PickPocket 32434.8 32787.64 1.011 NetMHC 54.0 56.0 22 0.5 NA NA NA NA NA NA 37254.765 37526.545 1.007 64.0 65.0 42265.45 42074.73 56.0 54.0 32787.64 32434.8 74.0 74.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.157142857142857 0.7000000000000001 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 4 6 SHVWTHSRD SHVWTRSRD PickPocket 24218.04 25017.04 1.033 NetMHC 54.0 61.0 56 0.071 NA NA NA NA NA NA 33153.67 33931.095 1.023 58.0 62.0 42845.15 42089.3 61.0 54.0 25017.04 24218.04 63.0 62.0 5.CECR2.ENST00000262608.8.missense.535R/H False -1.3428571428571427 -0.7714285714285714 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 4 6 TISCTGSSG TISCTRSSG PickPocket 31740.46 35367.39 1.114 NetMHC 54.0 69.0 5 1.0 NA NA NA NA NA NA 36915.345 39534.905 1.071 63.5 73.5 43702.42 42090.23 69.0 54.0 35367.39 31740.46 78.0 73.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.19999999999999998 0.5142857142857142 False False False 1 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 6 4 VVTTQKRNS VVTAQKRNS PickPocket 32085.75 28485.48 0.888 NetMHC 56.0 39.0 96 0.042 NA NA NA NA NA NA 37159.605 34157.16 0.919 65.0 54.0 39828.84 42233.46 39.0 56.0 28485.48 32085.75 69.0 74.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -2.5142857142857147 -0.7000000000000001 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 9 1 FTRLTSELN STRLTSELN PickPocket 11233.42 14252.45 1.269 PickPocket 29.0 38.0 171 0.959 NA NA NA NA NA NA 26733.44 28171.34 1.054 42.5 46.0 42090.23 42233.46 54.0 56.0 14252.45 11233.42 38.0 29.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.7714285714285715 -0.3714285714285715 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 5 5 EEEKTQEVK EEEKPQEVK NetMHC 42236.21 42913.81 1.016 NetMHC 56.0 61.0 185 0.038 NA NA NA NA NA NA 45582.925 46456.905 1.019 72.0 74.5 42913.81 42236.21 61.0 56.0 50000.0 48929.64 88.0 88.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.1142857142857143 -2.0571428571428574 True False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 8 2 KHGGVSLSK KPGGVSLSK PickPocket 6539.79 20149.14 3.081 PickPocket 13.0 53.0 140 0.179 NA NA NA NA NA NA 24389.595 31577.025 1.295 34.5 57.5 43004.91 42239.4 62.0 56.0 20149.14 6539.79 53.0 13.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.24285714285714294 0.3428571428571429 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 2 8 YQQRPGSAP YQQRPGSSP PickPocket 21269.21 20368.33 0.958 NetMHC 56.0 53.0 7 0.571 NA NA NA NA NA NA 31790.675 31138.39 0.979 56.0 53.0 41908.45 42312.14 53.0 56.0 20368.33 21269.21 53.0 56.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.5142857142857142 -1.5142857142857142 False False True 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 7 3 EKTQEVKVK EKPQEVKVK PickPocket 38150.11 15208.39 0.399 NetMHC 57.0 22.0 185 0.038 NA NA NA NA NA NA 40249.895 25270.105 0.628 68.5 31.5 35331.82 42349.68 22.0 57.0 15208.39 38150.11 41.0 80.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.0142857142857142 -1.014285714285714 True False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 1 9 SGGSHVWTH SGGSHVWTR PickPocket 11112.54 12382.34 1.114 PickPocket 29.0 33.0 56 0.071 NA NA NA NA NA NA 26733.405 27527.46 1.03 43.0 46.0 42672.58 42354.27 59.0 57.0 12382.34 11112.54 33.0 29.0 5.CECR2.ENST00000262608.8.missense.535R/H False -0.7142857142857143 -0.31428571428571433 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 5 5 EALNNLLTE EALNHLLTE PickPocket 32434.8 22942.68 0.707 NetMHC 57.0 54.0 30 0.1 NA NA NA NA NA NA 37433.52 32520.09 0.869 65.5 56.5 42097.5 42432.24 54.0 57.0 22942.68 32434.8 59.0 74.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.02857142857142847 0.7857142857142856 True False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 6 1, 2, 3 RTLLLAAAG SRTLLAAAG PickPocket 37333.42 30726.73 0.823 NetMHC 57.0 74.0 76 0.158 NA NA NA NA NA NA 39884.665 37467.34 0.939 68.5 73.0 44207.95 42435.91 74.0 57.0 30726.73 37333.42 72.0 80.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 2.342857142857143 2.342857142857143 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 3 7 TTVVVTTQK TTVVVTAQK NetMHC 42436.38 42705.84 1.006 NetMHC 57.0 59.0 96 0.042 NA NA NA NA NA NA 46218.19 39620.03 0.857 72.5 69.0 42705.84 42436.38 59.0 57.0 36534.22 50000.0 79.0 88.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 0.5428571428571433 1.4000000000000001 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 6 4 EEKTQEVKV EEKPQEVKV PickPocket 33869.37 29425.27 0.869 NetMHC 58.0 25.0 185 0.038 NA NA NA NA NA NA 38170.325 32858.8 0.861 67.0 47.5 36292.33 42471.28 25.0 58.0 29425.27 33869.37 70.0 76.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.014285714285714 -1.014285714285714 True False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 5 6, 7, 8, 9 GRSAGSTGQ GRSAGQHWA PickPocket 29108.61 23957.42 0.823 NetMHC 58.0 53.0 142 0.768 NA NA NA NA NA NA 35820.99 32946.32 0.92 63.5 57.0 41935.22 42533.37 53.0 58.0 23957.42 29108.61 61.0 69.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6857142857142857 -0.6857142857142857 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 7 NA SAGSTGQGS NA PickPocket 30726.73 NA NA NetMHC 58.0 NA 142 0.768 NA NA NA NA NA NA 36638.565 NA NA 65.0 NA NA 42550.4 NA 58.0 NA 30726.73 NA 72.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 8 2 TGSSGSIAS TRSSGSIAS PickPocket 10641.85 8571.13 0.805 PickPocket 27.0 20.0 5 1.0 NA NA NA NA NA NA 26618.01 25216.455 0.947 42.5 36.5 41861.78 42594.17 53.0 58.0 8571.13 10641.85 20.0 27.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.38571428571428573 0.4428571428571428 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 14 NA GSGEKAGCP NA PickPocket 20368.33 NA NA PickPocket 53.0 NA 142 0.768 NA NA NA NA NA NA 31490.0 NA NA 56.0 NA NA 42611.67 NA 59.0 NA 20368.33 NA 53.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.7857142857142857 -0.6714285714285715 False False True 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 6 4 AKVEMSHFE AKVAMSHFE PickPocket 27875.69 23699.6 0.85 NetMHC 59.0 40.0 113 0.044 NA NA NA NA NA NA 35246.91 31876.36 0.904 63.5 50.5 40053.12 42618.13 40.0 59.0 23699.6 27875.69 61.0 68.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.3000000000000001 -0.3000000000000001 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 1 9 WYQQRPGSA WYQQRPGSS PickPocket 9972.95 9865.62 0.989 PickPocket 25.0 25.0 7 0.571 NA NA NA NA NA NA 26322.295 26319.26 1.0 42.0 42.5 42772.9 42671.64 60.0 59.0 9865.62 9972.95 25.0 25.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.7857142857142858 -1.7857142857142858 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 6 4 LLHIYGSGG LLHTYGSGG NetMHC 42704.9 42372.14 0.992 NetMHC 59.0 57.0 120 0.233 NA NA NA NA NA NA 46352.45 46186.07 0.996 73.5 72.5 42372.14 42704.9 57.0 59.0 50000.0 50000.0 88.0 88.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.2857142857142857 0.914285714285714 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 7 3 LHIYGSGGY LHTYGSGGY PickPocket 30396.07 23444.56 0.771 NetMHC 60.0 58.0 120 0.233 NA NA NA NA NA NA 36598.6 32997.25 0.902 65.5 59.0 42549.94 42801.13 58.0 60.0 23444.56 30396.07 60.0 71.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.014285714285714266 0.3142857142857142 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 3 7 GSHVWTHSR GSHVWTRSR PickPocket 42051.98 38565.12 0.917 NetMHC 61.0 65.0 56 0.071 NA NA NA NA NA NA 42461.775 40932.55 0.964 72.5 73.0 43299.98 42871.57 65.0 61.0 38565.12 42051.98 81.0 84.0 5.CECR2.ENST00000262608.8.missense.535R/H False -1.3000000000000003 -0.7142857142857143 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 7 3 MDYLSDRCK MDCLSDRCK PickPocket 22209.93 18882.64 0.85 PickPocket 57.0 50.0 92 0.043 NA NA NA NA NA NA 32641.64 30971.94 0.949 60.0 56.5 43061.24 43073.35 63.0 63.0 18882.64 22209.93 50.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.0999999999999999 -1.042857142857143 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 2 8 TVTISCTGS TVTISCTRS PickPocket 39408.75 36534.22 0.927 NetMHC 63.0 52.0 5 1.0 NA NA NA NA NA NA 41249.68 39168.35 0.95 72.5 65.5 41802.48 43090.61 52.0 63.0 36534.22 39408.75 79.0 82.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.5142857142857142 1.2285714285714284 False False False 1 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 2 8 YSYGLLHIY YSYGLLHTY PickPocket 28795.36 31740.46 1.102 NetMHC 63.0 74.0 120 0.233 NA NA NA NA NA NA 35945.78 37961.78 1.056 66.0 73.5 44183.1 43096.2 74.0 63.0 31740.46 28795.36 73.0 69.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.8428571428571427 0.9142857142857143 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 1 9 LHTVSPEPA LHTVSPEPP PickPocket 11730.27 11986.87 1.022 PickPocket 31.0 32.0 245 0.486 NA NA NA NA NA NA 27443.1 27493.335 1.002 47.5 47.0 42999.8 43155.93 62.0 64.0 11986.87 11730.27 32.0 31.0 15.GGA1.ENST00000343632.4.missense.484P/A False -0.31428571428571433 -0.2571428571428572 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 1 9 AKTTVVVTT AKTTVVVTA PickPocket 17505.31 18478.42 1.056 PickPocket 47.0 49.0 96 0.042 NA NA NA NA NA NA 30357.955 31093.01 1.024 55.5 59.0 43707.6 43210.6 69.0 64.0 18478.42 17505.31 49.0 47.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.4000000000000001 1.4000000000000001 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 4 7, 8, 9 GGRSAGSTG GGRSAGQHW PickPocket 32434.8 15541.08 0.479 NetMHC 64.0 51.0 142 0.768 NA NA NA NA NA NA 37834.855 28600.435 0.756 69.0 46.5 41659.79 43234.91 51.0 64.0 15541.08 32434.8 42.0 74.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8285714285714286 -0.7857142857142857 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 3 7 LFGALVRSR LFGALVHSR PickPocket 31740.46 34610.27 1.09 NetMHC 65.0 61.0 210 0.686 NA NA NA NA NA NA 37502.425 38721.69 1.033 69.0 69.0 42833.11 43264.39 61.0 65.0 34610.27 31740.46 77.0 73.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.05714285714285732 1.6428571428571428 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 5 5 ISCTGSSGS ISCTRSSGS PickPocket 37739.56 17130.58 0.454 NetMHC 65.0 41.0 5 1.0 NA NA NA NA NA NA 40510.88 28614.4 0.706 72.5 43.5 40098.22 43282.2 41.0 65.0 17130.58 37739.56 46.0 80.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.20000000000000004 0.5 False False False 1 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 5 5 HVWTHSRDP HVWTRSRDP PickPocket 28485.48 16404.99 0.576 NetMHC 67.0 45.0 56 0.071 NA NA NA NA NA NA 36004.06 28568.85 0.793 68.0 44.5 40732.71 43522.64 45.0 67.0 16404.99 28485.48 44.0 69.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1714285714285717 -1.3000000000000003 False False True 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 4 7 LSRTLLLAA LSRTLLAAA PickPocket 9245.51 30068.96 3.252 PickPocket 22.0 71.0 76 0.158 NA NA NA NA NA NA 26418.47 37679.99 1.426 45.0 78.5 45291.02 43591.43 86.0 68.0 30068.96 9245.51 71.0 22.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.4 1.4 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 4 6 QGIANQDAA QGIANEDAA NetMHC 43674.52 43845.46 1.004 NetMHC 69.0 70.0 22 0.5 NA NA NA NA NA NA 46837.26 46387.55 0.99 78.5 79.0 43845.46 43674.52 70.0 69.0 48929.64 50000.0 88.0 88.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.08571428571428576 -0.08571428571428576 True False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 1 9 AGTLKFNPQ AGTLKFNPE PickPocket 18082.85 17888.25 0.989 PickPocket 48.0 48.0 136 0.25 NA NA NA NA NA NA 30892.395 30886.785 1.0 58.5 59.5 43885.32 43701.94 71.0 69.0 17888.25 18082.85 48.0 48.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.942857142857143 -0.0142857142857143 False False False 0 False 1 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 6 4 ALNNLLTEE ALNHLLTEE NetMHC 43704.3 43374.07 0.992 NetMHC 69.0 66.0 30 0.1 NA NA NA NA NA NA 46852.15 46687.035 0.996 78.5 77.0 43374.07 43704.3 66.0 69.0 50000.0 50000.0 88.0 88.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.7857142857142856 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 5 5 EASGYESRV EASGSESRV NetMHC 43708.56 42167.71 0.965 NetMHC 69.0 55.0 116 0.043 NA NA NA NA NA NA 46854.28 46083.855 0.984 78.5 71.5 42167.71 43708.56 55.0 69.0 50000.0 50000.0 88.0 88.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.0142857142857145 -1.0142857142857145 True False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 4 6 LKFNPQTDY LKFNPETDY NetMHC 43715.19 43923.32 1.005 NetMHC 69.0 71.0 136 0.25 NA NA NA NA NA NA 46059.14 45138.125 0.98 78.0 78.5 43923.32 43715.19 71.0 69.0 46352.93 48403.09 86.0 87.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.6142857142857143 -0.942857142857143 False False False 0 False 1 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 9 1 APTTVIYED SPTTVIYED NetMHC 43734.11 44150.6 1.01 NetMHC 69.0 74.0 7 0.571 NA NA NA NA NA NA 45295.645 42651.185 0.942 78.0 78.5 44150.6 43734.11 74.0 69.0 41151.77 46857.18 83.0 87.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.14285714285714274 0.8857142857142858 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 3 7 PCDDMDYLS PCDDMDCLS NetMHC 43774.34 43881.05 1.002 NetMHC 70.0 71.0 92 0.043 NA NA NA NA NA NA 45828.27 46940.525 1.024 78.5 79.5 43881.05 43774.34 71.0 70.0 50000.0 47882.2 88.0 87.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.9857142857142858 -0.5142857142857142 False False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 2 9 GGGGRSAGS GGGGRSAGQ PickPocket 14407.49 13212.86 0.917 PickPocket 39.0 35.0 142 0.768 NA NA NA NA NA NA 29091.395 28215.94 0.97 54.5 49.5 43219.02 43775.3 64.0 70.0 13212.86 14407.49 35.0 39.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.7857142857142857 -0.7285714285714285 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 7 3 SGYESRVEP SGSESRVEP PickPocket 16946.23 12653.21 0.747 PickPocket 46.0 34.0 116 0.043 NA NA NA NA NA NA 30373.56 28090.505 0.925 58.0 50.5 43527.8 43800.89 67.0 70.0 12653.21 16946.23 34.0 46.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.5714285714285712 -1.0142857142857145 False False True 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 5 5 GLLHIYGSG GLLHTYGSG NetMHC 43848.77 43122.33 0.983 NetMHC 70.0 63.0 120 0.233 NA NA NA NA NA NA 46924.385 40227.875 0.857 79.0 71.5 43122.33 43848.77 63.0 70.0 37333.42 50000.0 80.0 88.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.3142857142857142 0.9714285714285714 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 9 2 8 ERTEASGYE ERTEASGSE PickPocket 29425.27 32085.75 1.09 PickPocket 70.0 74.0 116 0.043 NA NA NA NA NA NA 36668.12 38304.3 1.045 70.5 76.0 44522.85 43910.97 78.0 71.0 32085.75 29425.27 74.0 70.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.2 -1.2 True False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 5 5 GIANQDAAQ GIANEDAAQ PickPocket 18279.56 22209.93 1.215 PickPocket 49.0 57.0 22 0.5 NA NA NA NA NA NA 31145.685 33192.68 1.066 60.5 65.5 44175.43 44011.81 74.0 72.0 22209.93 18279.56 57.0 49.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.2285714285714284 -0.08571428571428576 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 7 3 LNNLLTEEE LNHLLTEEE PickPocket 27278.95 23957.42 0.878 PickPocket 67.0 61.0 30 0.1 NA NA NA NA NA NA 35686.605 33783.395 0.947 70.0 64.5 43609.37 44094.26 68.0 73.0 23957.42 27278.95 61.0 67.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.02857142857142847 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 1 9 KTVTISCTG KTVTISCTR PickPocket 27575.71 29108.61 1.056 PickPocket 67.0 69.0 5 1.0 NA NA NA NA NA NA 35874.375 36429.17 1.015 70.5 69.0 43749.73 44173.04 69.0 74.0 29108.61 27575.71 69.0 67.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 1.2285714285714284 1.2285714285714284 False False False 1 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 7 3 GKHGGVSLS GKPGGVSLS NetMHC 44176.89 39664.56 0.898 NetMHC 74.0 38.0 140 0.179 NA NA NA NA NA NA 45015.5 27602.82 0.613 80.0 40.0 39664.56 44176.89 38.0 74.0 15541.08 45854.11 42.0 86.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.3428571428571429 0.3428571428571429 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 18 NA KAGCPWSGT NA NetMHC 44205.56 NA NA NetMHC 74.0 NA 142 0.768 NA NA NA NA NA NA 47102.78 NA NA 81.0 NA NA 44205.56 NA 74.0 NA 50000.0 NA 88.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.32857142857142857 0.02857142857142855 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 9 9 1 GSSGSIASN RSSGSIASN PickPocket 16763.86 9972.95 0.595 PickPocket 45.0 25.0 5 1.0 NA NA NA NA NA NA 30509.11 25781.925 0.845 60.0 38.0 41590.9 44254.36 51.0 75.0 9972.95 16763.86 25.0 45.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.0 0.4428571428571428 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 13 NA QGSGEKAGC NA PickPocket 38150.11 NA NA NetMHC 75.0 NA 142 0.768 NA NA NA NA NA NA 41207.745 NA NA 77.5 NA NA 44265.38 NA 75.0 NA 38150.11 NA 80.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6714285714285715 -0.6714285714285715 True True False 1 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 9 4 6 FGALVRSRT FGALVHSRT PickPocket 42051.98 40708.92 0.968 NetMHC 75.0 69.0 210 0.686 NA NA NA NA NA NA 43162.765 42219.865 0.978 79.5 76.0 43730.81 44273.55 69.0 75.0 40708.92 42051.98 83.0 84.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.09999999999999987 0.9857142857142857 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 12 NA GQGSGEKAG NA PickPocket 18882.64 NA NA PickPocket 50.0 NA 142 0.768 NA NA NA NA NA NA 31582.635 NA NA 62.5 NA NA 44282.63 NA 75.0 NA 18882.64 NA 50.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0857142857142859 -1.0857142857142859 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 9 2 8 KTTVVVTTQ KTTVVVTAQ PickPocket 38984.65 41151.77 1.056 NetMHC 75.0 82.0 96 0.042 NA NA NA NA NA NA 41638.91 43031.81 1.033 78.0 82.5 44911.85 44293.17 82.0 75.0 41151.77 38984.65 83.0 81.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.0000000000000002 1.4000000000000001 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 9 8 2 LVYCLQKCN LAYCLQKCN NetMHC 44314.74 44222.78 0.998 NetMHC 75.0 74.0 113 0.053 NA NA NA NA NA NA 45333.835 47111.39 1.039 80.5 81.0 44222.78 44314.74 74.0 75.0 50000.0 46352.93 88.0 86.0 6.USP18.ENST00000215794.7.missense.124A/V False -0.4857142857142857 0.7999999999999999 False False False 2 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 2 8 HEDLIGKHG HEDLIGKPG NetMHC 44324.83 44121.0 0.995 NetMHC 76.0 73.0 140 0.179 NA NA NA NA NA NA 46893.38 47060.5 1.004 82.0 80.5 44121.0 44324.83 73.0 76.0 50000.0 49461.93 88.0 88.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.44285714285714295 -0.44285714285714295 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 1 9 SPVKEEEKT SPVKEEEKP NetMHC 44328.17 44474.7 1.003 NetMHC 76.0 77.0 185 0.038 NA NA NA NA NA NA 47164.085 47237.35 1.002 82.0 82.5 44474.7 44328.17 77.0 76.0 50000.0 50000.0 88.0 88.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.1142857142857143 -1.8 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 10 NA STGQGSGEK NA PickPocket 38565.12 NA NA NetMHC 76.0 NA 142 0.768 NA NA NA NA NA NA 41470.16 NA NA 78.5 NA NA 44375.2 NA 76.0 NA 38565.12 NA 81.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.842857142857143 -1.0000000000000002 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 2 8 PVKEEEKTQ PVKEEEKPQ NetMHC 44415.57 44629.45 1.005 NetMHC 77.0 79.0 185 0.038 NA NA NA NA NA NA 47207.785 47314.725 1.002 82.5 83.5 44629.45 44415.57 79.0 77.0 50000.0 50000.0 88.0 88.0 12.NEFH.ENST00000310624.6.missense.830P/T False -3.2142857142857144 -2.1142857142857143 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 10 1, 2 LPLLLLLGA PLLLLLLGA PickPocket 43911.91 40708.92 0.927 NetMHC 77.0 65.0 101 0.891 NA NA NA NA NA NA 44188.5 42010.55 0.951 81.0 74.0 43312.18 44465.09 65.0 77.0 40708.92 43911.91 83.0 85.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.9142857142857146 3.028571428571429 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 9 8 2 NNLLTEEED NHLLTEEED PickPocket 24218.04 25289.19 1.044 PickPocket 62.0 64.0 30 0.1 NA NA NA NA NA NA 34343.73 34755.03 1.012 69.5 69.0 44220.87 44469.42 74.0 77.0 25289.19 24218.04 64.0 62.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 -1.0142857142857145 False False False 0 True 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 8 NA AGSTGQGSG NA PickPocket 36534.22 NA NA NetMHC 77.0 NA 142 0.768 NA NA NA NA NA NA 40512.88 NA NA 78.0 NA NA 44491.54 NA 77.0 NA 36534.22 NA 79.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 9 8 2 KTQEVKVKE KPQEVKVKE PickPocket 15044.73 32434.8 2.156 PickPocket 40.0 74.0 185 0.038 NA NA NA NA NA NA 29772.71 38574.645 1.296 59.0 77.0 44714.49 44500.69 80.0 78.0 32434.8 15044.73 74.0 40.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.4142857142857141 -1.014285714285714 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 3 7 EDLIGKHGG EDLIGKPGG NetMHC 44517.54 41865.85 0.94 NetMHC 78.0 53.0 140 0.179 NA NA NA NA NA NA 47258.77 27982.46 0.592 83.0 45.5 41865.85 44517.54 53.0 78.0 14099.07 50000.0 38.0 88.0 11.TPST2.ENST00000338754.4.missense.274P/H False -3.172065784643304e-17 -3.172065784643304e-17 True False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 7 3 GNLFNCECD GNPFNCECD PickPocket 20589.91 6978.43 0.339 PickPocket 54.0 14.0 303 0.135 NA NA NA NA NA NA 32593.51 23905.65 0.733 66.5 29.5 40832.87 44597.11 45.0 79.0 6978.43 20589.91 14.0 54.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 5 5 LAGNLFNCE LAGNPFNCE NetMHC 44599.04 44220.39 0.992 NetMHC 79.0 74.0 303 0.135 NA NA NA NA NA NA 47299.52 44790.52 0.947 83.5 80.0 44220.39 44599.04 74.0 79.0 45360.65 50000.0 86.0 88.0 13.ELFN2.ENST00000402918.2.missense.186P/L False -0.2571428571428572 0.6857142857142856 False False False 1 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 9 6 4 AGNLFNCEC AGNPFNCEC NetMHC 44606.25 39747.48 0.891 NetMHC 79.0 39.0 303 0.135 NA NA NA NA NA NA 44739.375 34908.22 0.78 82.0 55.0 39747.48 44606.25 39.0 79.0 30068.96 44872.5 71.0 85.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.5 False True False 2 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 9 1 9 DAVQGIANQ DAVQGIANE NetMHC 44623.17 44773.1 1.003 NetMHC 79.0 80.0 22 0.5 NA NA NA NA NA NA 47311.585 47386.55 1.002 83.5 84.0 44773.1 44623.17 80.0 79.0 50000.0 50000.0 88.0 88.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.0571428571428572 0.7000000000000001 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 9 1 HGGVSLSKI PGGVSLSKI PickPocket 37333.42 50000.0 1.339 NetMHC 79.0 84.0 140 0.179 NA NA NA NA NA NA 41005.35 47557.475 1.16 79.5 86.0 45114.95 44677.28 84.0 79.0 50000.0 37333.42 88.0 80.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.9428571428571428 0.9428571428571428 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 3 7 SYGLLHIYG SYGLLHTYG PickPocket 14882.82 50000.0 3.36 PickPocket 40.0 88.0 120 0.233 NA NA NA NA NA NA 29786.58 47512.115 1.595 60.0 85.5 45024.23 44690.34 83.0 80.0 50000.0 14882.82 88.0 40.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9714285714285714 0.9714285714285714 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 9 NA GSTGQGSGE NA PickPocket 36534.22 NA NA PickPocket 79.0 NA 142 0.768 NA NA NA NA NA NA 40619.525 NA NA 79.5 NA NA 44704.83 NA 80.0 NA 36534.22 NA 79.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.3857142857142857 -1.0000000000000002 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 2 8 GGSHVWTHS GGSHVWTRS NetMHC 44814.29 44103.82 0.984 NetMHC 81.0 73.0 56 0.071 NA NA NA NA NA NA 47407.145 47051.91 0.993 84.5 80.5 44103.82 44814.29 73.0 81.0 50000.0 50000.0 88.0 88.0 5.CECR2.ENST00000262608.8.missense.535R/H False -0.7714285714285714 -0.31428571428571433 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 2 8 LGWEFLAFT LGWEFLAST NetMHC 44815.74 45124.23 1.007 NetMHC 81.0 84.0 171 0.959 NA NA NA NA NA NA 46348.97 47562.115 1.026 84.0 86.0 45124.23 44815.74 84.0 81.0 50000.0 47882.2 88.0 87.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.8714285714285712 1.0571428571428572 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 9 4 6 YGLLHIYGS YGLLHTYGS PickPocket 13797.25 11857.88 0.859 PickPocket 37.0 31.0 120 0.233 NA NA NA NA NA NA 29332.205 27633.815 0.942 59.0 48.5 43409.75 44867.16 66.0 81.0 11857.88 13797.25 31.0 37.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.914285714285714 0.9714285714285714 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 9 8 2 PQTDYLTGT PETDYLTGT NetMHC 44982.35 45597.84 1.014 NetMHC 83.0 89.0 136 0.25 NA NA NA NA NA NA 47491.175 47798.92 1.006 85.5 88.5 45597.84 44982.35 89.0 83.0 50000.0 50000.0 88.0 88.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.5 -0.5 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 1 9 HHEDLIGKH HHEDLIGKP PickPocket 27575.71 30396.07 1.102 PickPocket 67.0 71.0 140 0.179 NA NA NA NA NA NA 36327.035 37807.795 1.041 75.5 78.0 45219.52 45078.36 85.0 84.0 30396.07 27575.71 71.0 67.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.8857142857142858 -0.7857142857142859 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 9 1 HSRDPEGSS RSRDPEGSS PickPocket 18679.43 15373.84 0.823 PickPocket 49.0 41.0 56 0.071 NA NA NA NA NA NA 31901.83 29645.73 0.929 66.5 56.0 43917.62 45124.23 71.0 84.0 15373.84 18679.43 41.0 49.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 11 1 PLLLLLGAS LLLLLLGAS NetMHC 45329.74 44996.48 0.993 NetMHC 87.0 83.0 101 0.891 NA NA NA NA NA NA 47664.87 47498.24 0.997 87.5 85.5 44996.48 45329.74 83.0 87.0 50000.0 50000.0 88.0 88.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.2571428571428567 2.9142857142857146 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 5 5 DDMDYLSDR DDMDCLSDR NetMHC 45692.66 45319.95 0.992 PickPocket 88.0 88.0 92 0.043 NA NA NA NA NA NA 47846.33 47659.975 0.996 89.0 87.0 45319.95 45692.66 86.0 90.0 50000.0 50000.0 88.0 88.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.1285714285714286 -0.9857142857142857 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 5 6, 9 SRTLLLAAA SRTLLAAAG PickPocket 41151.77 30726.73 0.747 PickPocket 83.0 72.0 76 0.158 NA NA NA NA NA NA 43565.535 37467.34 0.86 88.0 73.0 44207.95 45979.3 74.0 93.0 30726.73 41151.77 72.0 83.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 2.3000000000000003 2.3000000000000003 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 6 7 PLLPLLPLLL PLLPLLLLLL NetMHC 21178.51 26314.15 1.242 NetMHC 3.1 6.1 101 0.891 NA NA NA NA NA NA 27341.695 33511.535 1.226 19.05 25.55 26314.15 21178.51 6.1 3.1 40708.92 33504.88 45.0 35.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 4 7 QQRPGSAPTT QQRPGSSPTT PickPocket 11233.42 14564.23 1.297 PickPocket 3.5 6.8 7 0.571 NA NA NA NA NA NA 16726.485 20803.305 1.244 3.55 6.7 27042.38 22219.55 6.6 3.6 14564.23 11233.42 6.8 3.5 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.5714285714285714 -0.5714285714285714 True False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 3 10 PPPPLLPLLP PPPPLLPLLL NetMHC 22226.29 21815.29 0.982 NetMHC 3.6 3.4 101 0.891 NA NA NA NA NA NA 36113.145 26777.875 0.741 30.3 17.7 21815.29 22226.29 3.4 3.6 31740.46 50000.0 32.0 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 1.4857142857142858 1.4857142857142858 False False True 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 3 9 ATLSRTLLLA ATLSRTLLAA PickPocket 11479.16 13356.59 1.164 NetMHC 3.6 41.0 76 0.158 NA NA NA NA NA NA 16856.685 26746.715 1.587 3.65 23.3 40136.84 22234.21 41.0 3.6 13356.59 11479.16 5.6 3.7 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.0285714285714285 1.3142857142857143 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 2 10 SATLSRTLLL SATLSRTLLA PickPocket 21500.59 33144.32 1.542 NetMHC 3.9 43.0 76 0.158 NA NA NA NA NA NA 22233.185 36775.885 1.654 10.45 38.5 40407.45 22965.78 43.0 3.9 33144.32 21500.59 34.0 17.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.3142857142857143 1.3142857142857143 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 7 6, 10 LLPLLPLLLL LLPLLLLLLG PickPocket 5869.13 11233.42 1.914 PickPocket 0.6 3.5 101 0.891 NA NA NA NA NA NA 14482.245 18925.125 1.307 2.3 4.9 26616.83 23095.36 6.3 4.0 11233.42 5869.13 3.5 0.6 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 3.028571428571429 3.028571428571429 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 5 8 PPLLPLLPLL PPLLPLLLLL NetMHC 25069.88 30234.03 1.206 NetMHC 5.1 11.0 101 0.891 NA NA NA NA NA NA 37534.94 40117.015 1.069 31.05 34.0 30234.03 25069.88 11.0 5.1 50000.0 50000.0 57.0 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 2 9 VLCQRAKVEM VLCQRAKVAM PickPocket 18082.85 19295.7 1.067 NetMHC 5.4 5.7 113 0.044 NA NA NA NA NA NA 21734.13 22555.915 1.038 8.7 9.85 25816.13 25385.41 5.7 5.4 19295.7 18082.85 14.0 12.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.0714285714285712 0.0571428571428572 False False False 1 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 5 6 QRPGSAPTTV QRPGSSPTTV PickPocket 12517.05 12790.86 1.022 PickPocket 4.7 4.9 7 0.571 NA NA NA NA NA NA 18972.67 21250.11 1.12 5.05 7.15 29709.36 25428.29 9.4 5.4 12790.86 12517.05 4.9 4.7 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.2571428571428571 0.2571428571428571 True False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 8 1, 2, 4, 5 LPLLPLLLLL PLLPLLLLLL NetMHC 25501.86 26314.15 1.032 NetMHC 5.5 6.1 101 0.891 NA NA NA NA NA NA 34470.61 33511.535 0.972 27.25 25.55 26314.15 25501.86 6.1 5.5 40708.92 43439.36 45.0 49.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 3.028571428571429 3.028571428571429 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 2 9 YQPCDDMDYL YQPCDDMDCL PickPocket 5324.55 5560.06 1.044 PickPocket 0.5 0.5 92 0.043 NA NA NA NA NA NA 16636.515 18401.53 1.106 4.0 6.75 31243.0 27948.48 13.0 7.5 5560.06 5324.55 0.5 0.5 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.5142857142857142 -0.5142857142857142 False False False 1 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 10 1 ARPPQQPVPT PRPPQQPVPT PickPocket 7945.94 20368.33 2.563 PickPocket 1.5 15.0 245 0.486 NA NA NA NA NA NA 18001.285 26874.375 1.493 4.55 16.0 33380.42 28056.63 17.0 7.6 20368.33 7945.94 15.0 1.5 15.GGA1.ENST00000343632.4.missense.484P/A False -1.1857142857142855 -1.1857142857142855 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 9 1, 3, 4 PLLPLLLLLG LLPLLLLLLG NetMHC 29821.75 26616.83 0.893 NetMHC 9.6 6.3 101 0.891 NA NA NA NA NA NA 39910.875 18925.125 0.474 33.3 4.9 26616.83 29821.75 6.3 9.6 11233.42 50000.0 3.5 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.4285714285714293 3.028571428571429 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 4 7 VRPLELVYCL VRPLELAYCL PickPocket 13212.86 14722.66 1.114 PickPocket 5.4 7.0 113 0.053 NA NA NA NA NA NA 21567.075 17943.6 0.832 7.55 5.05 21164.54 29921.29 3.1 9.7 14722.66 13212.86 7.0 5.4 6.USP18.ENST00000215794.7.missense.124A/V False 1.9000000000000001 1.9000000000000001 False False False 1 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 7 4 ALVRSRTYDM ALVHSRTYDM PickPocket 21040.32 19505.61 0.927 NetMHC 12.0 15.0 210 0.686 NA NA NA NA NA NA 25792.375 25978.1 1.007 14.0 14.5 32450.59 30544.43 15.0 12.0 19505.61 21040.32 14.0 16.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.9142857142857144 -0.09999999999999987 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 9 2 PARPPQQPVP PPRPPQQPVP NetMHC 31195.71 35499.65 1.138 NetMHC 13.0 22.0 245 0.486 NA NA NA NA NA NA 40597.855 42749.825 1.053 35.0 39.5 35499.65 31195.71 22.0 13.0 50000.0 50000.0 57.0 57.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 5 6 VSPEPARPPQ VSPEPPRPPQ PickPocket 6469.41 7054.34 1.09 PickPocket 0.8 1.0 245 0.486 NA NA NA NA NA NA 19811.53 20795.83 1.05 8.4 10.5 34537.32 33153.65 20.0 16.0 7054.34 6469.41 1.0 0.8 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -0.8571428571428571 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 5 6 LKFNPQTDYL LKFNPETDYL NetMHC 33452.35 33914.48 1.014 NetMHC 17.0 18.0 136 0.25 NA NA NA NA NA NA 41726.175 41957.24 1.006 37.0 37.5 33914.48 33452.35 18.0 17.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.4714285714285715 -0.942857142857143 False False False 0 False 1 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 1 10 LMVCELAGNL LMVCELAGNP PickPocket 18478.42 29108.61 1.575 PickPocket 13.0 28.0 303 0.135 NA NA NA NA NA NA 26084.345 36731.345 1.408 15.0 52.0 44354.08 33690.27 76.0 17.0 29108.61 18478.42 28.0 13.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6428571428571427 2.0714285714285716 False False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 10 1 YLSDRCKILQ CLSDRCKILQ PickPocket 9865.62 14407.49 1.46 PickPocket 2.5 6.7 92 0.043 NA NA NA NA NA NA 21824.125 23892.33 1.095 10.25 11.85 33377.17 33782.63 17.0 18.0 14407.49 9865.62 6.7 2.5 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.6571428571428573 -0.27142857142857146 False False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 9 2 DYLSDRCKIL DCLSDRCKIL NetMHC 34093.64 33762.52 0.99 NetMHC 18.0 18.0 92 0.043 NA NA NA NA NA NA 36965.55 41881.26 1.133 31.0 37.5 33762.52 34093.64 18.0 18.0 50000.0 39837.46 57.0 44.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.27142857142857163 -0.27142857142857146 False False False 1 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 1 10 QKAVRPLELV QKAVRPLELA PickPocket 20589.91 20589.91 1.0 PickPocket 16.0 16.0 113 0.053 NA NA NA NA NA NA 27428.315 27419.975 1.0 17.5 17.5 34250.04 34266.72 19.0 19.0 20589.91 20589.91 16.0 16.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.9142857142857144 0.9142857142857144 True False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 10 1 TQKRNSRRQL AQKRNSRRQL PickPocket 28485.48 26985.39 0.947 NetMHC 19.0 23.0 96 0.042 NA NA NA NA NA NA 31406.16 31373.98 0.999 23.0 24.0 35762.57 34326.84 23.0 19.0 26985.39 28485.48 25.0 27.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -2.5 -2.5 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 6 5 KFNPQTDYLT KFNPETDYLT PickPocket 30068.96 33869.37 1.126 NetMHC 19.0 21.0 136 0.25 NA NA NA NA NA NA 32199.935 34522.025 1.072 24.5 28.0 35174.68 34330.91 21.0 19.0 33869.37 30068.96 35.0 30.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.0714285714285716 -1.0714285714285716 False False False 0 False 1 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 6 5 SPEPARPPQQ SPEPPRPPQQ PickPocket 15208.39 16946.23 1.114 PickPocket 7.6 9.8 245 0.486 NA NA NA NA NA NA 24932.195 22838.28 0.916 13.8 9.05 28730.33 34656.0 8.3 20.0 16946.23 15208.39 9.8 7.6 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -1.6857142857142855 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 8 3 LVRSRTYDMD LVHSRTYDMD PickPocket 27875.69 39837.46 1.429 NetMHC 21.0 21.0 210 0.686 NA NA NA NA NA NA 31472.54 37496.735 1.191 24.0 32.5 35156.01 35069.39 21.0 21.0 39837.46 27875.69 44.0 27.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.7714285714285716 -0.5428571428571428 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 9 2 HIYGSGGYAL HTYGSGGYAL PickPocket 22209.93 30396.07 1.369 PickPocket 18.0 30.0 120 0.233 NA NA NA NA NA NA 28776.8 34080.48 1.184 20.0 30.0 37764.89 35343.67 30.0 22.0 30396.07 22209.93 30.0 18.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.32857142857142857 0.32857142857142857 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 10 1 IYGSGGYALY TYGSGGYALY PickPocket 35367.39 44389.61 1.255 NetMHC 22.0 29.0 120 0.233 NA NA NA NA NA NA 35411.06 41002.825 1.158 30.0 39.5 37616.04 35454.73 29.0 22.0 44389.61 35367.39 50.0 38.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.1999999999999999 0.32857142857142857 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 2 9 ALGWEFLAFT ALGWEFLAST NetMHC 35835.78 43492.5 1.214 NetMHC 23.0 67.0 171 0.959 NA NA NA NA NA NA 40354.14 45687.35 1.132 37.0 60.5 43492.5 35835.78 67.0 23.0 47882.2 44872.5 54.0 51.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.8714285714285712 1.0571428571428572 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 1 10 PALGWEFLAF PALGWEFLAS NetMHC 36280.14 44383.84 1.223 NetMHC 24.0 76.0 171 0.959 NA NA NA NA NA NA 43140.07 47191.92 1.094 40.5 66.5 44383.84 36280.14 76.0 24.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.9142857142857143 1.0571428571428572 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 7 4 PEPARPPQQP PEPPRPPQQP PickPocket 23957.42 23444.56 0.979 PickPocket 21.0 20.0 245 0.486 NA NA NA NA NA NA 30238.71 27313.725 0.903 23.0 16.5 31182.89 36520.0 13.0 25.0 23444.56 23957.42 20.0 21.0 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -1.7999999999999996 False False True 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 1 10 SVLCQRAKVE SVLCQRAKVA NetMHC 36784.91 36890.12 1.003 NetMHC 26.0 26.0 113 0.044 NA NA NA NA NA NA 39647.18 42128.52 1.063 37.0 40.0 36890.12 36784.91 26.0 26.0 47366.92 42509.45 54.0 48.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.9857142857142857 0.4999999999999999 False False False 1 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 6 5 LIGKHGGVSL LIGKPGGVSL PickPocket 28485.48 31060.99 1.09 PickPocket 27.0 31.0 140 0.179 NA NA NA NA NA NA 32898.15 29744.755 0.904 27.5 19.5 28428.52 37310.82 8.0 28.0 31060.99 28485.48 31.0 27.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.10000000000000002 0.05714285714285713 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 4 7 VNEALNNLLT VNEALNHLLT PickPocket 21734.48 22942.68 1.056 PickPocket 17.0 19.0 30 0.1 NA NA NA NA NA NA 29954.06 29446.325 0.983 24.0 21.0 35949.97 38173.64 23.0 31.0 22942.68 21734.48 19.0 17.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.7857142857142856 0.7857142857142856 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 4 9 PPPLLPLLPL PPPLLPLLLL NetMHC 38950.93 37931.97 0.974 NetMHC 35.0 30.0 101 0.891 NA NA NA NA NA NA 43940.285 40220.71 0.915 45.5 39.0 37931.97 38950.93 30.0 35.0 42509.45 48929.64 48.0 56.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 3 8 SVNEALNNLL SVNEALNHLL NetMHC 38983.8 36348.9 0.932 NetMHC 35.0 25.0 30 0.1 NA NA NA NA NA NA 44491.9 43174.45 0.97 46.0 41.0 36348.9 38983.8 25.0 35.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.3857142857142856 0.3857142857142856 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 8 3 LAFTRLTSEL LASTRLTSEL NetMHC 39280.61 39267.87 1.0 NetMHC 36.0 36.0 171 0.959 NA NA NA NA NA NA 44640.305 44633.935 1.0 46.5 46.5 39267.87 39280.61 36.0 36.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.3714285714285715 0.8999999999999997 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 1 10 MYQPCDDMDY MYQPCDDMDC PickPocket 15881.05 15373.84 0.968 PickPocket 8.4 7.8 92 0.043 NA NA NA NA NA NA 27664.31 28174.62 1.018 22.7 26.9 40975.4 39447.57 46.0 37.0 15373.84 15881.05 7.8 8.4 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 +4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 Not Run Not Run protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-E*01:01 10 3 1 SAAAAAAAVI AAAAAAAAVI NetMHC 39812.46 39812.05 1.0 NetMHC 39.0 39.0 128 0.977 NA NA NA NA NA NA 41160.955 44107.57 1.072 43.5 47.0 39812.05 39812.46 39.0 39.0 48403.09 42509.45 55.0 48.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A False 2.5285714285714285 2.5285714285714285 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 2 9 KSVNEALNNL KSVNEALNHL PickPocket 18882.64 18882.64 1.0 PickPocket 13.0 13.0 30 0.1 NA NA NA NA NA NA 29403.2 29096.295 0.99 26.5 24.5 39309.95 39923.76 36.0 40.0 18882.64 18882.64 13.0 13.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 2 9 KAVRPLELVY KAVRPLELAY NetMHC 40129.47 43168.07 1.076 NetMHC 41.0 64.0 113 0.053 NA NA NA NA NA NA 41784.415 45525.135 1.09 45.0 59.0 43168.07 40129.47 64.0 41.0 47882.2 43439.36 54.0 49.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.1285714285714286 0.9142857142857144 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 3 8 AVRPLELVYC AVRPLELAYC PickPocket 37739.56 50000.0 1.325 NetMHC 41.0 59.0 113 0.053 NA NA NA NA NA NA 38969.275 46337.68 1.189 41.0 58.0 42675.36 40198.99 59.0 41.0 50000.0 37739.56 57.0 41.0 6.USP18.ENST00000215794.7.missense.124A/V False 1.1285714285714286 1.1285714285714286 False True False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 9 2 VEMSHFEPNE VAMSHFEPNE PickPocket 31060.99 38984.65 1.255 PickPocket 31.0 43.0 113 0.044 NA NA NA NA NA NA 35669.175 39631.005 1.111 36.5 42.5 40277.36 40277.36 42.0 42.0 38984.65 31060.99 43.0 31.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.9000000000000001 -0.3000000000000001 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 1 10 LYYSYGLLHI LYYSYGLLHT PickPocket 20813.9 21269.21 1.022 PickPocket 16.0 17.0 120 0.233 NA NA NA NA NA NA 30597.35 32419.005 1.06 29.0 42.5 43568.8 40380.8 68.0 42.0 21269.21 20813.9 17.0 16.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9142857142857143 0.9142857142857143 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 4 7 GWEFLAFTRL GWEFLASTRL PickPocket 32085.75 50000.0 1.558 PickPocket 33.0 57.0 171 0.959 NA NA NA NA NA NA 36257.755 46580.07 1.285 38.0 60.5 43160.14 40429.76 64.0 43.0 50000.0 32085.75 57.0 33.0 22.PANX2.ENST00000395842.2.missense.147S/F False 1.4000000000000001 1.4000000000000001 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 7 4 PGSAPTTVIY PGSSPTTVIY NetMHC 40484.47 41890.78 1.035 NetMHC 43.0 53.0 7 0.571 NA NA NA NA NA NA 45242.235 45945.39 1.016 50.0 55.0 41890.78 40484.47 53.0 43.0 50000.0 50000.0 57.0 57.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.8857142857142858 0.9571428571428572 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 8 3 GSAPTTVIYE GSSPTTVIYE PickPocket 13797.25 17888.25 1.297 PickPocket 6.1 12.0 7 0.571 NA NA NA NA NA NA 27146.555 29907.42 1.102 24.55 32.5 41926.59 40495.86 53.0 43.0 17888.25 13797.25 12.0 6.1 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.12857142857142861 0.9571428571428572 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 9 2 NLFNCECDLF NPFNCECDLF NetMHC 40641.14 43932.84 1.081 NetMHC 44.0 71.0 303 0.135 NA NA NA NA NA NA 45320.57 46966.42 1.036 50.5 64.0 43932.84 40641.14 71.0 44.0 50000.0 50000.0 57.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 True 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 7 4 IGKHGGVSLS IGKPGGVSLS NetMHC 41231.54 33876.33 0.822 NetMHC 48.0 18.0 140 0.179 NA NA NA NA NA NA 45615.77 41938.165 0.919 52.5 37.5 33876.33 41231.54 18.0 48.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.3428571428571429 0.3428571428571429 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 4 7 TVSPEPARPP TVSPEPPRPP NetMHC 41372.32 40057.9 0.968 NetMHC 49.0 40.0 245 0.486 NA NA NA NA NA NA 45686.16 45028.95 0.986 53.0 48.5 40057.9 41372.32 40.0 49.0 50000.0 50000.0 57.0 57.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.7999999999999996 -0.31428571428571433 False False True 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 1 10 RVSLFGALVR RVSLFGALVH PickPocket 34610.27 31060.99 0.897 PickPocket 36.0 31.0 210 0.686 NA NA NA NA NA NA 37997.335 36054.125 0.949 42.5 39.0 41047.26 41384.4 47.0 49.0 31060.99 34610.27 31.0 36.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False 1.6428571428571428 2.1714285714285713 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 10 1 EMSHFEPNEY AMSHFEPNEY PickPocket 23957.42 14882.82 0.621 PickPocket 21.0 7.1 113 0.044 NA NA NA NA NA NA 32732.575 27673.35 0.845 35.5 25.05 40463.88 41507.73 43.0 50.0 14882.82 23957.42 7.1 21.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.9714285714285715 -1.1285714285714286 True False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 2 9 MVCELAGNLF MVCELAGNPF NetMHC 41580.55 44539.71 1.071 NetMHC 50.0 78.0 303 0.135 NA NA NA NA NA NA 45790.275 47269.855 1.032 53.5 67.5 44539.71 41580.55 78.0 50.0 50000.0 50000.0 57.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6857142857142856 1.4714285714285713 False False False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 7 4 FNPQTDYLTG FNPETDYLTG PickPocket 4676.23 4478.16 0.958 PickPocket 0.4 0.3 136 0.25 NA NA NA NA NA NA 23300.735 23574.685 1.012 26.7 29.65 42671.21 41925.24 59.0 53.0 4478.16 4676.23 0.3 0.4 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.9000000000000001 -0.9000000000000001 False False False 0 False 1 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 2 9 VSLFGALVRS VSLFGALVHS PickPocket 24747.82 25564.3 1.033 PickPocket 22.0 23.0 210 0.686 NA NA NA NA NA NA 33359.445 33602.59 1.007 38.0 37.0 41640.88 41971.07 51.0 54.0 25564.3 24747.82 23.0 22.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False 0.9857142857142857 2.1714285714285713 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 4 8 TLSRTLLLAA TLSRTLLAAA PickPocket 23192.26 50000.0 2.156 PickPocket 20.0 57.0 76 0.158 NA NA NA NA NA NA 32641.01 47181.845 1.445 37.0 66.5 44363.69 42089.76 76.0 54.0 50000.0 23192.26 57.0 20.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.4 1.4 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 5 6 RPLELVYCLQ RPLELAYCLQ NetMHC 42220.2 38473.86 0.911 NetMHC 55.0 33.0 113 0.053 NA NA NA NA NA NA 46110.1 44236.93 0.959 56.0 45.0 38473.86 42220.2 33.0 55.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.8571428571428571 1.9000000000000001 False False False 1 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 8 3 GNLFNCECDL GNPFNCECDL PickPocket 33144.32 11233.42 0.339 PickPocket 34.0 3.5 303 0.135 NA NA NA NA NA NA 37709.695 26062.99 0.691 45.0 24.75 40892.56 42275.07 46.0 56.0 11233.42 33144.32 3.5 34.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 7 4 VWTHSRDPEG VWTRSRDPEG PickPocket 9759.45 10527.33 1.079 PickPocket 2.5 3.0 56 0.071 NA NA NA NA NA NA 26053.42 25969.75 0.997 29.75 26.0 41412.17 42347.39 49.0 57.0 10527.33 9759.45 3.0 2.5 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5 -1.3428571428571427 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 10 2, 3 LLPLLLLLGA LPLLLLLLGA PickPocket 12517.05 50000.0 3.995 PickPocket 4.7 57.0 101 0.891 NA NA NA NA NA NA 27532.575 48348.125 1.756 31.35 78.0 46696.25 42548.1 99.0 58.0 50000.0 12517.05 57.0 4.7 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.9142857142857146 3.028571428571429 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 9 2 AFTRLTSELN ASTRLTSELN NetMHC 42743.29 42913.81 1.004 PickPocket 57.0 57.0 171 0.959 NA NA NA NA NA NA 46371.645 46456.905 1.002 58.5 59.0 42913.81 42743.29 61.0 60.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.7714285714285715 0.24285714285714272 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 3 8 YQQRPGSAPT YQQRPGSSPT PickPocket 30396.07 45360.65 1.492 PickPocket 30.0 52.0 7 0.571 NA NA NA NA NA NA 36598.6 44398.125 1.213 45.0 59.0 43435.6 42801.13 66.0 60.0 45360.65 30396.07 52.0 30.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.1142857142857143 -1.1142857142857143 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 20 NA AGCPWSGTGQ NA NetMHC 42825.68 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 46412.84 NA NA 59.0 NA NA 42825.68 NA 61.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.1857142857142857 0.02857142857142855 False False False 1 False 0 +22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 Not Run Not Run protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-E*01:01 10 10 10 FNMSSFKLKQ FNMSSFKLKE PickPocket 12117.27 11986.87 0.989 PickPocket 4.3 4.1 117 0.496 NA NA NA NA NA NA 27491.41 27582.37 1.003 32.65 34.05 43177.87 42865.55 64.0 61.0 11986.87 12117.27 4.1 4.3 14.LGALS2.ENST00000215886.4.missense.132E/Q False -0.9000000000000001 -0.07142857142857155 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 6 5 RPGSAPTTVI RPGSSPTTVI NetMHC 43044.0 43218.07 1.004 PickPocket 57.0 57.0 7 0.571 NA NA NA NA NA NA 46522.0 46609.035 1.002 60.0 60.5 43218.07 43044.0 64.0 63.0 50000.0 50000.0 57.0 57.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.9571428571428572 0.9571428571428572 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 4 7 RTEASGYESR RTEASGSESR PickPocket 26407.71 35752.13 1.354 PickPocket 25.0 38.0 116 0.043 NA NA NA NA NA NA 34796.535 40332.24 1.159 44.5 60.0 44912.35 43185.36 82.0 64.0 35752.13 26407.71 38.0 25.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.3571428571428572 -1.2 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 4 7 VKEEEKTQEV VKEEEKPQEV NetMHC 43390.97 42201.47 0.973 PickPocket 57.0 29.0 185 0.038 NA NA NA NA NA NA 46695.485 35973.42 0.77 61.5 42.0 42201.47 43390.97 55.0 66.0 29745.37 50000.0 29.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.0571428571428574 -2.0571428571428574 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 3 8 VCELAGNLFN VCELAGNPFN PickPocket 26694.99 22942.68 0.859 PickPocket 25.0 19.0 303 0.135 NA NA NA NA NA NA 35048.62 32708.815 0.933 45.5 38.5 42474.95 43402.25 58.0 66.0 22942.68 26694.99 19.0 25.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6857142857142856 0.7000000000000001 False False False 1 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 9 2 SAPTTVIYED SSPTTVIYED PickPocket 19505.61 9146.01 0.469 PickPocket 14.0 2.1 7 0.571 NA NA NA NA NA NA 31458.155 26546.31 0.844 40.0 36.55 43946.61 43410.7 71.0 66.0 9146.01 19505.61 2.1 14.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.14285714285714274 0.9571428571428572 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 21 NA GCPWSGTGQH NA PickPocket 25017.04 NA NA PickPocket 22.0 NA 142 0.768 NA NA NA NA NA NA 34217.385 NA NA 44.0 NA NA 43417.73 NA 66.0 NA 25017.04 NA 22.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.4142857142857141 -0.32857142857142857 False False False 1 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 4 7 CELAGNLFNC CELAGNPFNC PickPocket 35752.13 29425.27 0.823 PickPocket 38.0 29.0 303 0.135 NA NA NA NA NA NA 39609.85 35801.97 0.904 52.5 42.0 42178.67 43467.57 55.0 67.0 29425.27 35752.13 29.0 38.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.5 0.6857142857142856 True True False 2 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 5 6 ELAGNLFNCE ELAGNPFNCE NetMHC 43661.77 42762.7 0.979 PickPocket 57.0 45.0 303 0.135 NA NA NA NA NA NA 46830.885 41516.765 0.887 62.5 52.5 42762.7 43661.77 60.0 68.0 40270.83 50000.0 45.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L False -0.2571428571428572 0.6857142857142856 True False False 1 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 7 4 IANQDAAQGI IANEDAAQGI NetMHC 43681.62 44133.41 1.01 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 46840.81 47066.705 1.005 63.0 65.0 44133.41 43681.62 73.0 69.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 -0.08571428571428576 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 9 2 VRSRTYDMDV VHSRTYDMDV PickPocket 36141.06 32787.64 0.907 PickPocket 39.0 34.0 210 0.686 NA NA NA NA NA NA 39917.95 37822.42 0.948 54.0 47.5 42857.2 43694.84 61.0 69.0 32787.64 36141.06 34.0 39.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 10 1 FTRLTSELNF STRLTSELNF PickPocket 11112.54 14099.07 1.269 PickPocket 3.4 6.4 171 0.959 NA NA NA NA NA NA 27418.825 28847.85 1.052 36.2 37.2 43596.63 43725.11 68.0 69.0 14099.07 11112.54 6.4 3.4 22.PANX2.ENST00000395842.2.missense.147S/F False 0.27142857142857135 0.27142857142857135 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 1 10 LLHTVSPEPA LLHTVSPEPP PickPocket 32787.64 33504.88 1.022 PickPocket 34.0 35.0 245 0.486 NA NA NA NA NA NA 38265.13 38832.28 1.015 51.5 54.5 44159.68 43742.62 74.0 69.0 33504.88 32787.64 35.0 34.0 15.GGA1.ENST00000343632.4.missense.484P/A False -0.31428571428571433 0.7857142857142857 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 3 8 ERTEASGYES ERTEASGSES NetMHC 43798.97 45557.39 1.04 PickPocket 54.0 57.0 116 0.043 NA NA NA NA NA NA 45582.945 47778.695 1.048 62.0 73.0 45557.39 43798.97 89.0 70.0 50000.0 47366.92 57.0 54.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.2142857142857142 -1.2 True False False 0 False 0 +4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 Not Run Not Run protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-E*01:01 10 2 10 ASAAAAAAAV ASAAAAAAAA PickPocket 26985.39 26985.39 1.0 PickPocket 25.0 25.0 128 0.977 NA NA NA NA NA NA 35441.765 36055.29 1.017 48.0 54.5 45125.19 43898.14 84.0 71.0 26985.39 26985.39 25.0 25.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A False 2.142857142857143 2.142857142857143 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 3 8 LCQRAKVEMS LCQRAKVAMS PickPocket 30396.07 36141.06 1.189 PickPocket 30.0 39.0 113 0.044 NA NA NA NA NA NA 37196.79 40160.4 1.08 51.0 56.5 44179.74 43997.51 74.0 72.0 36141.06 30396.07 39.0 30.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.6857142857142857 0.0571428571428572 False False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 4 7 CQRAKVEMSH CQRAKVAMSH PickPocket 11857.88 11986.87 1.011 PickPocket 4.0 4.1 113 0.044 NA NA NA NA NA NA 27935.795 26790.0 0.959 38.0 27.55 41593.13 44013.71 51.0 72.0 11986.87 11857.88 4.1 4.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.5 -0.5 True False False 1 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 9 2 TTQKRNSRRQ TAQKRNSRRQ NetMHC 44043.25 44115.25 1.002 PickPocket 51.0 57.0 96 0.042 NA NA NA NA NA NA 44457.875 47057.625 1.058 62.0 65.0 44115.25 44043.25 73.0 73.0 50000.0 44872.5 57.0 51.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.6000000000000005 -2.5142857142857147 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 5 6 WEFLAFTRLT WEFLASTRLT NetMHC 44134.83 43136.32 0.977 PickPocket 57.0 57.0 171 0.959 NA NA NA NA NA NA 47067.415 46568.16 0.989 65.5 60.0 43136.32 44134.83 63.0 74.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.8999999999999997 1.4000000000000001 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 7 4 DMDYLSDRCK DMDCLSDRCK NetMHC 44135.31 44483.36 1.008 PickPocket 50.0 44.0 92 0.043 NA NA NA NA NA NA 44262.46 42160.41 0.953 62.0 60.5 44483.36 44135.31 77.0 74.0 39837.46 44389.61 44.0 50.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.0999999999999999 -0.9857142857142857 False False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 3 8 QPCDDMDYLS QPCDDMDCLS NetMHC 44152.51 44358.89 1.005 PickPocket 57.0 57.0 92 0.043 NA NA NA NA NA NA 47076.255 47179.445 1.002 65.5 66.5 44358.89 44152.51 76.0 74.0 50000.0 50000.0 57.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.9857142857142858 -0.5142857142857142 True False False 1 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 9 2 NQDAAQGIAK NEDAAQGIAK PickPocket 23957.42 50000.0 2.087 PickPocket 21.0 57.0 22 0.5 NA NA NA NA NA NA 34126.265 47742.985 1.399 48.0 72.5 45485.97 44295.11 88.0 75.0 50000.0 23957.42 57.0 21.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False 0.3 0.35714285714285715 False False False 0 True 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 5 6 KEEEKTQEVK KEEEKPQEVK PickPocket 38150.11 39837.46 1.044 PickPocket 42.0 44.0 185 0.038 NA NA NA NA NA NA 41246.105 42644.25 1.034 59.0 66.0 45451.04 44342.1 88.0 76.0 39837.46 38150.11 44.0 42.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.1142857142857143 -2.0571428571428574 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 6 5 EFLAFTRLTS EFLASTRLTS NetMHC 44382.89 42983.5 0.968 PickPocket 52.0 30.0 171 0.959 NA NA NA NA NA NA 45118.5 36689.785 0.813 64.0 46.0 42983.5 44382.89 62.0 76.0 30396.07 45854.11 30.0 52.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.24285714285714272 1.4000000000000001 True False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 8 3 EPARPPQQPV EPPRPPQQPV NetMHC 44515.62 42220.2 0.948 PickPocket 57.0 57.0 245 0.486 NA NA NA NA NA NA 47257.81 46110.1 0.976 67.5 56.0 42220.2 44515.62 55.0 78.0 50000.0 50000.0 57.0 57.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.7285714285714289 -1.7285714285714289 True False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 9 2 GYESRVEPPH GSESRVEPPH PickPocket 11857.88 12382.34 1.044 PickPocket 4.0 4.5 116 0.043 NA NA NA NA NA NA 28224.36 28645.155 1.015 41.5 43.25 44907.97 44590.84 82.0 79.0 12382.34 11857.88 4.5 4.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.5714285714285714 -1.4000000000000001 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 9 2 KHGGVSLSKI KPGGVSLSKI PickPocket 40270.83 50000.0 1.242 PickPocket 45.0 57.0 140 0.179 NA NA NA NA NA NA 42433.235 47907.215 1.129 62.0 74.5 45814.43 44595.64 92.0 79.0 50000.0 40270.83 57.0 45.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.9428571428571428 0.9428571428571428 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 7 4 LELVYCLQKC LELAYCLQKC NetMHC 44606.25 43419.16 0.973 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 47303.125 46709.58 0.987 68.0 61.5 43419.16 44606.25 66.0 79.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.6142857142857141 1.9000000000000001 False True False 2 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 4 7 TLKFNPQTDY TLKFNPETDY NetMHC 44629.45 44915.24 1.006 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 47314.725 47457.62 1.003 68.0 69.5 44915.24 44629.45 82.0 79.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.6142857142857143 -0.942857142857143 False False False 0 False 1 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 9 1 LLLAAAGGSS TLLAAAGGSS NetMHC 44668.58 44213.23 0.99 PickPocket 56.0 57.0 76 0.158 NA NA NA NA NA NA 47065.255 47106.615 1.001 67.5 65.5 44213.23 44668.58 74.0 79.0 50000.0 49461.93 57.0 56.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 0.42857142857142855 2.342857142857143 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 3 8 HTVSPEPARP HTVSPEPPRP PickPocket 30396.07 11479.16 0.378 PickPocket 30.0 3.7 245 0.486 NA NA NA NA NA NA 37541.745 25889.6 0.69 55.0 22.85 40300.04 44687.42 42.0 80.0 11479.16 30396.07 3.7 30.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.6857142857142855 -0.31428571428571433 False False True 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 6 5 DDMDYLSDRC DDMDCLSDRC NetMHC 44694.69 45005.24 1.007 PickPocket 57.0 57.0 92 0.043 NA NA NA NA NA NA 47347.345 47502.62 1.003 68.5 70.0 45005.24 44694.69 83.0 80.0 50000.0 50000.0 57.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.042857142857143 -0.9857142857142857 False True False 1 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 8 1, 2 TLLLAAAGGS RTLLAAAGGS NetMHC 44709.19 44101.91 0.986 PickPocket 57.0 57.0 76 0.158 NA NA NA NA NA NA 47354.595 47050.955 0.994 68.5 65.0 44101.91 44709.19 73.0 80.0 50000.0 50000.0 57.0 57.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.0857142857142856 2.342857142857143 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 16 NA SGEKAGCPWS NA PickPocket 17695.75 NA NA PickPocket 12.0 NA 142 0.768 NA NA NA NA NA NA 31212.865 NA NA 46.0 NA NA 44729.98 NA 80.0 NA 17695.75 NA 12.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 5 6 TEASGYESRV TEASGSESRV NetMHC 44831.75 44279.77 0.988 PickPocket 57.0 57.0 116 0.043 NA NA NA NA NA NA 47415.875 47139.885 0.994 69.0 66.0 44279.77 44831.75 75.0 81.0 50000.0 50000.0 57.0 57.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.0142857142857145 -1.0142857142857145 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 2 9 YYSYGLLHIY YYSYGLLHTY PickPocket 28485.48 31060.99 1.09 PickPocket 27.0 31.0 120 0.233 NA NA NA NA NA NA 36671.47 38407.99 1.047 54.0 61.0 45754.99 44857.46 91.0 81.0 31060.99 28485.48 31.0 27.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.8428571428571427 0.9142857142857143 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 7 4 FLAFTRLTSE FLASTRLTSE PickPocket 16946.23 16404.99 0.968 PickPocket 9.8 9.1 171 0.959 NA NA NA NA NA NA 30903.54 30332.56 0.982 45.4 42.05 44260.13 44860.85 75.0 81.0 16404.99 16946.23 9.1 9.8 22.PANX2.ENST00000395842.2.missense.147S/F False -0.5142857142857143 1.4000000000000001 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 5 6 QRAKVEMSHF QRAKVAMSHF NetMHC 44892.89 41964.27 0.935 PickPocket 57.0 57.0 113 0.044 NA NA NA NA NA NA 47446.445 45982.135 0.969 69.5 55.0 41964.27 44892.89 53.0 82.0 50000.0 50000.0 57.0 57.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.35714285714285715 -0.35714285714285715 True False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 8 3 WTHSRDPEGS WTRSRDPEGS PickPocket 18679.43 13070.67 0.7 PickPocket 13.0 5.3 56 0.071 NA NA NA NA NA NA 31798.555 28806.885 0.906 47.5 41.65 44543.1 44917.68 78.0 82.0 13070.67 18679.43 5.3 13.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 8 3 ELVYCLQKCN ELAYCLQKCN NetMHC 45012.56 44080.44 0.979 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 47506.28 47040.22 0.99 70.0 65.0 44080.44 45012.56 73.0 83.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V False -0.4857142857142857 0.8571428571428571 True False False 2 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 1 10 KSPVKEEEKT KSPVKEEEKP PickPocket 9550.53 10301.97 1.079 PickPocket 2.4 2.9 185 0.038 NA NA NA NA NA NA 27295.915 27934.855 1.023 42.7 45.95 45567.74 45041.3 89.0 83.0 10301.97 9550.53 2.9 2.4 12.NEFH.ENST00000310624.6.missense.830P/T False -2.1142857142857143 -1.8 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 8 3 KVEMSHFEPN KVAMSHFEPN PickPocket 33504.88 26407.71 0.788 PickPocket 35.0 25.0 113 0.044 NA NA NA NA NA NA 39274.79 35467.695 0.903 59.5 51.5 44527.68 45044.7 78.0 84.0 26407.71 33504.88 25.0 35.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.1285714285714286 -0.3000000000000001 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 8 3 VTTQKRNSRR VTAQKRNSRR NetMHC 45051.53 44239.07 0.982 PickPocket 57.0 54.0 96 0.042 NA NA NA NA NA NA 47525.765 45802.995 0.964 70.5 64.5 44239.07 45051.53 75.0 84.0 47366.92 50000.0 54.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.6 -1.8 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 1 10 REERTEASGY REERTEASGS NetMHC 45075.42 45985.26 1.02 PickPocket 57.0 57.0 116 0.043 NA NA NA NA NA NA 47537.71 47992.63 1.01 70.5 75.0 45985.26 45075.42 93.0 84.0 50000.0 50000.0 57.0 57.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.342857142857143 -1.342857142857143 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 10 1 VYCLQKCNVP AYCLQKCNVP NetMHC 45113.49 46140.27 1.023 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 47556.745 48070.135 1.011 70.5 76.0 46140.27 45113.49 95.0 84.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V False -0.28571428571428564 0.6142857142857141 False False True 2 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 5 6 FGALVRSRTY FGALVHSRTY NetMHC 45120.79 46358.45 1.027 PickPocket 54.0 57.0 210 0.686 NA NA NA NA NA NA 46243.855 48179.225 1.042 69.0 77.0 46358.45 45120.79 97.0 84.0 50000.0 47366.92 57.0 54.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.5428571428571428 0.9857142857142857 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 10 3 8 LGWEFLAFTR LGWEFLASTR NetMHC 45137.88 46808.02 1.037 PickPocket 57.0 57.0 171 0.959 NA NA NA NA NA NA 47568.94 48404.01 1.018 71.0 78.5 46808.02 45137.88 100.0 85.0 50000.0 50000.0 57.0 57.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.35714285714285704 1.0571428571428572 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 7 NA RSAGSTGQGS NA PickPocket 18082.85 NA NA PickPocket 12.0 NA 142 0.768 NA NA NA NA NA NA 31638.47 NA NA 48.5 NA NA 45194.09 NA 85.0 NA 18082.85 NA 12.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 10 1 QDAAQGIAKE EDAAQGIAKE PickPocket 38565.12 48403.09 1.255 PickPocket 42.0 55.0 22 0.5 NA NA NA NA NA NA 41886.455 47045.9 1.123 63.5 72.5 45688.71 45207.79 90.0 85.0 48403.09 38565.12 55.0 42.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.45714285714285713 0.35714285714285715 True False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 17 NA GEKAGCPWSG NA PickPocket 41151.77 NA NA PickPocket 46.0 NA 142 0.768 NA NA NA NA NA NA 43189.07 NA NA 65.5 NA NA 45226.37 NA 85.0 NA 41151.77 NA 46.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False 0.02857142857142855 0.02857142857142855 False False False 1 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 10 2 9 LHTVSPEPAR LHTVSPEPPR PickPocket 14099.07 13947.35 0.989 PickPocket 6.4 6.2 245 0.486 NA NA NA NA NA NA 29680.345 29519.195 0.995 46.2 45.1 45091.04 45261.62 84.0 86.0 13947.35 14099.07 6.2 6.4 15.GGA1.ENST00000343632.4.missense.484P/A False -0.8571428571428571 -0.2571428571428572 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 7 4 AKVEMSHFEP AKVAMSHFEP PickPocket 36931.66 32434.8 0.878 PickPocket 40.0 33.0 113 0.044 NA NA NA NA NA NA 41112.8 38296.515 0.931 63.0 53.5 44158.23 45293.94 74.0 86.0 32434.8 36931.66 33.0 40.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.1285714285714286 -0.3000000000000001 False False True 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 6 5 ISCTGSSGSI ISCTRSSGSI NetMHC 45313.08 44344.96 0.979 PickPocket 57.0 40.0 5 1.0 NA NA NA NA NA NA 47656.54 40638.31 0.853 71.5 58.0 44344.96 45313.08 76.0 86.0 36931.66 50000.0 40.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.08571428571428566 0.5 False False False 1 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 10 1 LFNCECDLFG PFNCECDLFG PickPocket 32085.75 50000.0 1.558 PickPocket 33.0 57.0 303 0.135 NA NA NA NA NA NA 38706.515 48069.645 1.242 60.0 76.0 46139.29 45327.28 95.0 87.0 50000.0 32085.75 57.0 33.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.5999999999999999 0.5999999999999999 False False False 2 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 5 6 NEALNNLLTE NEALNHLLTE PickPocket 38150.11 34237.82 0.897 PickPocket 42.0 36.0 30 0.1 NA NA NA NA NA NA 41745.565 39734.295 0.952 64.5 61.0 45230.77 45341.02 86.0 87.0 34237.82 38150.11 36.0 42.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.02857142857142847 0.7857142857142856 False False False 0 True 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 8 3 ANQDAAQGIA ANEDAAQGIA PickPocket 30068.96 34610.27 1.151 PickPocket 30.0 36.0 22 0.5 NA NA NA NA NA NA 37713.575 40091.475 1.063 58.5 62.5 45572.68 45358.19 89.0 87.0 34610.27 30068.96 36.0 30.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False 0.35714285714285715 0.35714285714285715 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 6 5 GALVRSRTYD GALVHSRTYD NetMHC 45397.0 46028.58 1.014 PickPocket 57.0 57.0 210 0.686 NA NA NA NA NA NA 47698.5 48014.29 1.007 72.0 75.5 46028.58 45397.0 94.0 87.0 50000.0 50000.0 57.0 57.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.5857142857142856 -0.05714285714285732 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 6 5 EEEKTQEVKV EEEKPQEVKV NetMHC 45446.62 43858.27 0.965 PickPocket 57.0 57.0 185 0.038 NA NA NA NA NA NA 47723.31 46929.135 0.983 72.5 64.0 43858.27 45446.62 71.0 88.0 50000.0 50000.0 57.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.014285714285714 -1.014285714285714 True False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 1 10 RSGGSHVWTH RSGGSHVWTR PickPocket 17130.58 19088.05 1.114 PickPocket 10.0 14.0 56 0.071 NA NA NA NA NA NA 31300.65 32339.74 1.033 49.0 51.5 45591.43 45470.72 89.0 88.0 19088.05 17130.58 14.0 10.0 5.CECR2.ENST00000262608.8.missense.535R/H False -0.7142857142857143 -0.31428571428571433 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 10 1 RSRTYDMDVR HSRTYDMDVR PickPocket 28485.48 34610.27 1.215 PickPocket 27.0 36.0 210 0.686 NA NA NA NA NA NA 36982.525 40470.075 1.094 57.5 66.0 46329.88 45479.57 96.0 88.0 34610.27 28485.48 36.0 27.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 6 6, 7, 8, 9, 10 GRSAGSTGQG GRSAGQHWAR NetMHC 45481.54 45609.19 1.003 PickPocket 57.0 54.0 142 0.768 NA NA NA NA NA NA 47740.77 46488.055 0.974 72.5 72.0 45609.19 45481.54 90.0 88.0 47366.92 50000.0 54.0 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6285714285714287 -0.6285714285714287 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 10 1 YESRVEPPHE SESRVEPPHE PickPocket 17316.93 22209.93 1.283 PickPocket 12.0 18.0 116 0.043 NA NA NA NA NA NA 31428.29 33787.995 1.075 50.5 52.5 45366.06 45539.65 87.0 89.0 22209.93 17316.93 18.0 12.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.957142857142857 -1.5714285714285712 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 10 1 HSRDPEGSSR RSRDPEGSSR NetMHC 45541.12 44587.93 0.979 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 47770.56 47293.965 0.99 73.0 67.5 44587.93 45541.12 78.0 89.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 4 7 VTISCTGSSG VTISCTRSSG NetMHC 45570.71 45036.92 0.988 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 47785.355 47518.46 0.994 73.0 70.0 45036.92 45570.71 83.0 89.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.19999999999999998 1.2285714285714284 False False False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 2 9 AGTLKFNPQT AGTLKFNPET PickPocket 21734.48 21970.92 1.011 PickPocket 17.0 18.0 136 0.25 NA NA NA NA NA NA 33658.015 33866.91 1.006 53.0 54.5 45762.9 45581.55 91.0 89.0 21970.92 21734.48 18.0 17.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.942857142857143 -0.0142857142857143 False False False 0 False 1 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 7 4 SCTGSSGSIA SCTRSSGSIA NetMHC 45586.99 45060.8 0.988 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 47793.495 47530.4 0.994 73.0 70.5 45060.8 45586.99 84.0 89.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.4428571428571428 0.4428571428571428 False False False 1 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 7 4 LLHIYGSGGY LLHTYGSGGY NetMHC 45587.96 45497.29 0.998 PickPocket 57.0 57.0 120 0.233 NA NA NA NA NA NA 47793.98 47748.645 0.999 73.0 72.5 45497.29 45587.96 88.0 89.0 50000.0 50000.0 57.0 57.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.014285714285714266 0.914285714285714 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 5 6 TVVVTTQKRN TVVVTAQKRN NetMHC 45654.6 45415.65 0.995 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 47827.3 47707.825 0.998 73.5 72.5 45415.65 45654.6 88.0 90.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -1.8 1.0000000000000002 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 8 3 MDYLSDRCKI MDCLSDRCKI PickPocket 44872.5 38150.11 0.85 PickPocket 51.0 42.0 92 0.043 NA NA NA NA NA NA 45267.745 42109.27 0.93 70.5 68.0 46068.43 45662.99 94.0 90.0 38150.11 44872.5 42.0 51.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.27142857142857146 -0.27142857142857146 False False False 1 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 8 3 LHIYGSGGYA LHTYGSGGYA NetMHC 45670.41 45926.11 1.006 PickPocket 57.0 55.0 120 0.233 NA NA NA NA NA NA 47835.205 47164.6 0.986 73.5 74.0 45926.11 45670.41 93.0 90.0 48403.09 50000.0 55.0 57.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.39999999999999997 0.3142857142857142 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 3 8 TVTISCTGSS TVTISCTRSS NetMHC 45673.86 45093.48 0.987 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 47836.93 47546.74 0.994 73.5 70.5 45093.48 45673.86 84.0 90.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.5 1.2285714285714284 False False False 1 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 1 10 QWYQQRPGSA QWYQQRPGSS NetMHC 45692.16 45897.8 1.005 PickPocket 52.0 52.0 7 0.571 NA NA NA NA NA NA 45773.135 45629.225 0.997 71.0 72.0 45897.8 45692.16 92.0 90.0 45360.65 45854.11 52.0 52.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.7857142857142858 -1.7857142857142858 True False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 4 7 VQGIANQDAA VQGIANEDAA NetMHC 45704.03 45900.29 1.004 PickPocket 56.0 54.0 22 0.5 NA NA NA NA NA NA 47582.98 46891.245 0.985 73.5 73.5 45900.29 45704.03 93.0 91.0 47882.2 49461.93 54.0 56.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.08571428571428576 -0.0571428571428572 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 5 6 DLIGKHGGVS DLIGKPGGVS NetMHC 45717.39 45725.29 1.0 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 47858.695 47862.645 1.0 74.0 74.0 45725.29 45717.39 91.0 91.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.7000000000000001 0.05714285714285713 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 7 1, 2, 3 RTLLLAAAGG SRTLLAAAGG NetMHC 45722.81 46525.27 1.018 PickPocket 57.0 57.0 76 0.158 NA NA NA NA NA NA 47861.405 48262.635 1.008 74.0 77.5 46525.27 45722.81 98.0 91.0 50000.0 50000.0 57.0 57.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.742857142857143 2.342857142857143 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 10 6 5 RAKVEMSHFE RAKVAMSHFE NetMHC 45723.31 45260.16 0.99 PickPocket 57.0 57.0 113 0.044 NA NA NA NA NA NA 47861.655 47630.08 0.995 74.0 71.5 45260.16 45723.31 86.0 91.0 50000.0 50000.0 57.0 57.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.3000000000000001 -0.3000000000000001 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 6 5 GIANQDAAQG GIANEDAAQG PickPocket 41599.44 47366.92 1.139 PickPocket 47.0 54.0 22 0.5 NA NA NA NA NA NA 43662.865 46625.405 1.068 69.0 73.0 45883.89 45726.29 92.0 91.0 47366.92 41599.44 54.0 47.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.5428571428571427 -0.08571428571428576 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 3 8 SLFGALVRSR SLFGALVHSR NetMHC 45865.01 45847.65 1.0 PickPocket 57.0 57.0 210 0.686 NA NA NA NA NA NA 47932.505 47923.825 1.0 74.5 74.5 45847.65 45865.01 92.0 92.0 50000.0 50000.0 57.0 57.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.05714285714285732 2.1714285714285713 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 3 8 GTLKFNPQTD GTLKFNPETD NetMHC 45866.52 46007.66 1.003 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 47933.26 48003.83 1.001 74.5 75.5 46007.66 45866.52 94.0 92.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.9857142857142855 -0.5000000000000001 False False False 0 False 1 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 1 10 SAKTTVVVTT SAKTTVVVTA NetMHC 45866.52 45867.5 1.0 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 47933.26 47933.75 1.0 74.5 74.5 45867.5 45866.52 92.0 92.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.4000000000000001 1.4000000000000001 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 18 NA EKAGCPWSGT NA NetMHC 45874.45 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 47937.225 NA NA 74.5 NA NA 45874.45 NA 92.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.32857142857142857 0.02857142857142855 True False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 19 NA KAGCPWSGTG NA NetMHC 45907.71 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 47953.855 NA NA 75.0 NA NA 45907.71 NA 93.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.3285714285714286 0.02857142857142855 False False False 1 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 7 4 EEKTQEVKVK EEKPQEVKVK NetMHC 45921.63 43010.04 0.937 PickPocket 57.0 57.0 185 0.038 NA NA NA NA NA NA 47960.815 46505.02 0.97 75.0 59.5 43010.04 45921.63 62.0 93.0 50000.0 50000.0 57.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.0142857142857142 -1.014285714285714 True False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 1 10 NKSVNEALNN NKSVNEALNH PickPocket 35752.13 36141.06 1.011 PickPocket 38.0 39.0 30 0.1 NA NA NA NA NA NA 40844.33 40807.62 0.999 65.5 63.5 45474.18 45936.53 88.0 93.0 36141.06 35752.13 39.0 38.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6 -0.21428571428571427 False False False 0 True 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 8 3 CTGSSGSIAS CTRSSGSIAS PickPocket 37333.42 26123.53 0.7 PickPocket 41.0 24.0 5 1.0 NA NA NA NA NA NA 41647.155 35751.175 0.858 67.0 55.5 45378.82 45960.89 87.0 93.0 26123.53 37333.42 24.0 41.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.38571428571428573 0.4428571428571428 True False False 1 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 10 1 NLLTEEEDYQ HLLTEEEDYQ NetMHC 45979.8 45998.7 1.0 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 47989.9 47999.35 1.0 75.0 75.0 45998.7 45979.8 93.0 93.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -2.7857142857142856 -1.0142857142857145 False False False 0 True 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 6 5 VVVTTQKRNS VVVTAQKRNS NetMHC 45979.8 45917.66 0.999 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 47989.9 47958.83 0.999 75.0 75.0 45917.66 45979.8 93.0 93.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -2.5142857142857147 0.5428571428571433 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 4 7 TTVVVTTQKR TTVVVTAQKR NetMHC 46004.18 45633.85 0.992 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 48002.09 47816.925 0.996 75.0 73.5 45633.85 46004.18 90.0 93.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -0.7000000000000001 1.4000000000000001 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 4 7 EDLIGKHGGV EDLIGKPGGV NetMHC 46038.55 45626.46 0.991 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 48019.275 47813.23 0.996 75.5 73.5 45626.46 46038.55 90.0 94.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.05714285714285713 0.05714285714285713 True False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 6 5 HVWTHSRDPE HVWTRSRDPE NetMHC 46043.51 45411.73 0.986 PickPocket 57.0 55.0 56 0.071 NA NA NA NA NA NA 48021.755 46907.41 0.977 75.5 71.0 45411.73 46043.51 87.0 94.0 48403.09 50000.0 55.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5428571428571423 -1.3000000000000003 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 1 10 IAGTLKFNPQ IAGTLKFNPE NetMHC 46065.46 46172.24 1.002 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 48032.73 48086.12 1.001 75.5 76.0 46172.24 46065.46 95.0 94.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.942857142857143 1.1285714285714286 False False False 0 False 1 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 6 5 EASGYESRVE EASGSESRVE NetMHC 46065.94 45836.74 0.995 PickPocket 57.0 57.0 116 0.043 NA NA NA NA NA NA 48032.97 47918.37 0.998 75.5 74.5 45836.74 46065.94 92.0 94.0 50000.0 50000.0 57.0 57.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.4000000000000001 -1.0142857142857145 True False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 9 2 LVYCLQKCNV LAYCLQKCNV NetMHC 46072.92 46650.8 1.013 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 48036.46 48325.4 1.006 75.5 78.0 46650.8 46072.92 99.0 94.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.3 0.7999999999999999 False False False 2 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 2 9 EERTEASGYE EERTEASGSE NetMHC 46097.35 46597.82 1.011 PickPocket 57.0 57.0 116 0.043 NA NA NA NA NA NA 48048.675 48298.91 1.005 75.5 77.5 46597.82 46097.35 98.0 94.0 50000.0 50000.0 57.0 57.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.2 -1.2 True False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-E*01:01 10 6 5 PLELVYCLQK PLELAYCLQK NetMHC 46104.34 44922.05 0.974 PickPocket 57.0 57.0 113 0.053 NA NA NA NA NA NA 48052.17 47461.025 0.988 75.5 69.5 44922.05 46104.34 82.0 94.0 50000.0 50000.0 57.0 57.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.7999999999999999 1.9000000000000001 False False False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 8 3 NPQTDYLTGT NPETDYLTGT NetMHC 46148.75 46224.73 1.002 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 48074.375 48112.365 1.001 76.0 76.5 46224.73 46148.75 96.0 95.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.5 -0.5 False False False 0 True 1 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 7 4 ASGYESRVEP ASGSESRVEP NetMHC 46160.74 46090.87 0.998 PickPocket 54.0 49.0 116 0.043 NA NA NA NA NA NA 46763.83 44765.115 0.957 74.5 71.5 46090.87 46160.74 94.0 95.0 43439.36 47366.92 49.0 54.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.5714285714285712 -1.0142857142857145 False False True 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 7 4 VVTTQKRNSR VVTAQKRNSR NetMHC 46171.22 45390.12 0.983 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 48085.61 47695.06 0.992 76.0 72.0 45390.12 46171.22 87.0 95.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.0571428571428574 -0.7000000000000001 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 9 2 NNLLTEEEDY NHLLTEEEDY NetMHC 46188.23 46243.73 1.001 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 48094.115 48121.865 1.001 76.0 76.5 46243.73 46188.23 96.0 95.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.742857142857143 -1.0142857142857145 False False False 0 True 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 10 1 TQEVKVKEPP PQEVKVKEPP PickPocket 31740.46 50000.0 1.575 PickPocket 32.0 57.0 185 0.038 NA NA NA NA NA NA 38965.835 48453.45 1.243 63.5 78.5 46906.9 46191.21 100.0 95.0 50000.0 31740.46 57.0 32.0 12.NEFH.ENST00000310624.6.missense.830P/T False -0.8714285714285713 -0.8714285714285713 False False True 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 15 NA GSGEKAGCPW NA NetMHC 46215.22 NA NA PickPocket 54.0 NA 142 0.768 NA NA NA NA NA NA 46791.07 NA NA 74.5 NA NA 46215.22 NA 95.0 NA 47366.92 NA 54.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8571428571428574 -0.6714285714285715 False False False 1 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-E*01:01 10 8 3 SGYESRVEPP SGSESRVEPP PickPocket 38565.12 28795.36 0.747 PickPocket 42.0 28.0 116 0.043 NA NA NA NA NA NA 42393.915 37563.365 0.886 68.5 62.0 46331.37 46222.71 96.0 95.0 28795.36 38565.12 28.0 42.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.6142857142857143 -1.0142857142857145 False False True 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 3 8 AVQGIANQDA AVQGIANEDA NetMHC 46238.24 46398.59 1.003 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 48119.12 48199.295 1.002 76.5 77.0 46398.59 46238.24 97.0 96.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 0.7000000000000001 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 9 2 KTQEVKVKEP KPQEVKVKEP PickPocket 37333.42 50000.0 1.339 PickPocket 41.0 57.0 185 0.038 NA NA NA NA NA NA 41811.355 48286.31 1.155 68.5 77.5 46572.62 46289.29 98.0 96.0 50000.0 37333.42 57.0 41.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.1428571428571428 -1.014285714285714 False False True 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 14 NA QGSGEKAGCP NA NetMHC 46295.8 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48147.9 NA NA 76.5 NA NA 46295.8 NA 96.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.7857142857142857 -0.6714285714285715 True False True 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 11 NA STGQGSGEKA NA NetMHC 46339.89 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48169.945 NA NA 76.5 NA NA 46339.89 NA 96.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.5285714285714287 -1.0000000000000002 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 5 6 SHVWTHSRDP SHVWTRSRDP PickPocket 39408.75 33504.88 0.85 PickPocket 44.0 35.0 56 0.071 NA NA NA NA NA NA 42883.09 39516.85 0.922 70.5 62.0 45528.82 46357.43 89.0 97.0 33504.88 39408.75 35.0 44.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1714285714285717 -0.7714285714285714 False False True 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 12 NA TGQGSGEKAG NA PickPocket 35752.13 NA NA PickPocket 38.0 NA 142 0.768 NA NA NA NA NA NA 41069.84 NA NA 67.5 NA NA 46387.55 NA 97.0 NA 35752.13 NA 38.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0857142857142859 -1.0857142857142859 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 8 3 EKTQEVKVKE EKPQEVKVKE NetMHC 46420.68 43870.12 0.945 PickPocket 57.0 28.0 185 0.038 NA NA NA NA NA NA 48210.34 36332.74 0.754 77.0 49.5 43870.12 46420.68 71.0 97.0 28795.36 50000.0 28.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.4142857142857141 -1.014285714285714 True False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 2 9 WYQQRPGSAP WYQQRPGSSP PickPocket 41599.44 40270.83 0.968 PickPocket 47.0 45.0 7 0.571 NA NA NA NA NA NA 44017.095 43335.71 0.985 72.0 71.0 46400.59 46434.75 97.0 97.0 40270.83 41599.44 45.0 47.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.5142857142857142 -1.5142857142857142 False False True 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 3 8 PVKEEEKTQE PVKEEEKPQE NetMHC 46449.34 44377.11 0.955 PickPocket 57.0 57.0 185 0.038 NA NA NA NA NA NA 48224.67 47188.555 0.979 77.0 66.5 44377.11 46449.34 76.0 97.0 50000.0 50000.0 57.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T False -3.1571428571428575 -2.1142857142857143 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 9 2 TGSSGSIASN TRSSGSIASN PickPocket 39408.75 31740.46 0.805 PickPocket 44.0 32.0 5 1.0 NA NA NA NA NA NA 42935.065 38870.08 0.905 70.5 62.5 45999.7 46461.38 93.0 97.0 31740.46 39408.75 32.0 44.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.0 0.4428571428571428 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 3 9, 10 GGGGRSAGST GGGGRSAGQH PickPocket 45854.11 42971.89 0.937 PickPocket 52.0 49.0 142 0.768 NA NA NA NA NA NA 46159.0 44620.815 0.967 74.5 72.5 46269.74 46463.89 96.0 97.0 42971.89 45854.11 49.0 52.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8285714285714286 -0.7285714285714285 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 5 6 CDDMDYLSDR CDDMDCLSDR NetMHC 46494.59 46546.91 1.001 PickPocket 57.0 57.0 92 0.043 NA NA NA NA NA NA 48247.295 48273.455 1.001 77.5 77.5 46546.91 46494.59 98.0 98.0 50000.0 50000.0 57.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.1285714285714286 -0.5142857142857142 True False False 1 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 9 2 THSRDPEGSS TRSRDPEGSS NetMHC 46502.62 46646.26 1.003 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 48251.31 48323.13 1.001 77.5 78.0 46646.26 46502.62 99.0 98.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 4 7 GSHVWTHSRD GSHVWTRSRD NetMHC 46515.22 46703.81 1.004 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 48257.61 48351.905 1.002 77.5 78.0 46703.81 46515.22 99.0 98.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H False -1.3428571428571427 -0.7142857142857143 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 7 4 ALNNLLTEEE ALNHLLTEEE NetMHC 46523.27 46373.49 0.997 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 48261.635 48186.745 0.998 77.5 77.0 46373.49 46523.27 97.0 98.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.7857142857142856 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 10 1 GSSGSIASNY RSSGSIASNY NetMHC 46529.29 45208.76 0.972 PickPocket 57.0 49.0 5 1.0 NA NA NA NA NA NA 48264.645 44324.06 0.918 77.5 67.0 45208.76 46529.29 85.0 98.0 43439.36 50000.0 49.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.07142857142857147 0.4428571428571428 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 8 3 GKHGGVSLSK GKPGGVSLSK PickPocket 42051.98 14252.45 0.339 PickPocket 47.0 6.5 140 0.179 NA NA NA NA NA NA 44297.18 29644.19 0.669 72.5 44.75 45035.93 46542.38 83.0 98.0 14252.45 42051.98 6.5 47.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.24285714285714294 0.3428571428571429 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 10 4 7 PCDDMDYLSD PCDDMDCLSD NetMHC 46553.49 46635.64 1.002 PickPocket 57.0 57.0 92 0.043 NA NA NA NA NA NA 48276.745 48317.82 1.001 77.5 78.0 46635.64 46553.49 99.0 98.0 50000.0 50000.0 57.0 57.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.9857142857142857 -0.5142857142857142 False False False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 10 1 QTDYLTGTDG ETDYLTGTDG NetMHC 46570.09 46809.05 1.005 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 48285.045 48404.525 1.002 77.5 78.5 46809.05 46570.09 100.0 98.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.45714285714285713 -0.45714285714285713 True False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 5 6 TISCTGSSGS TISCTRSSGS NetMHC 46580.7 45839.73 0.984 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 48290.35 47919.865 0.992 77.5 74.5 45839.73 46580.7 92.0 98.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.20000000000000004 0.5142857142857142 False False False 1 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 1 10 LHHEDLIGKH LHHEDLIGKP NetMHC 46597.82 46811.07 1.005 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 48298.91 48405.535 1.002 77.5 78.5 46811.07 46597.82 100.0 98.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.8857142857142858 -0.18571428571428594 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 4 8, 9, 10 GGGRSAGSTG GGGRSAGQHW NetMHC 46599.84 46066.44 0.989 PickPocket 57.0 57.0 142 0.768 NA NA NA NA NA NA 48299.92 48033.22 0.994 77.5 75.5 46066.44 46599.84 94.0 98.0 50000.0 50000.0 57.0 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8285714285714286 -0.7285714285714286 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 2 9 SGGSHVWTHS SGGSHVWTRS NetMHC 46620.52 46687.16 1.001 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 48310.26 48343.58 1.001 77.5 78.0 46687.16 46620.52 99.0 98.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H False -0.7714285714285714 -0.31428571428571433 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 6 5 EALNNLLTEE EALNHLLTEE NetMHC 46621.54 46581.18 0.999 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 48310.77 48290.59 1.0 77.5 77.5 46581.18 46621.54 98.0 98.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.7857142857142856 True False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 3 8 YSYGLLHIYG YSYGLLHTYG PickPocket 37333.42 50000.0 1.339 PickPocket 41.0 57.0 120 0.233 NA NA NA NA NA NA 41995.63 48525.875 1.155 70.0 78.5 47051.75 46657.84 100.0 99.0 50000.0 37333.42 57.0 41.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9714285714285714 0.9714285714285714 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 1 10 EDAVQGIANQ EDAVQGIANE NetMHC 46663.41 46745.79 1.002 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 48331.705 48372.895 1.001 78.0 78.0 46745.79 46663.41 99.0 99.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.0571428571428572 0.7000000000000001 True False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-E*01:01 10 4 7 LFGALVRSRT LFGALVHSRT NetMHC 46689.18 46499.12 0.996 PickPocket 57.0 57.0 210 0.686 NA NA NA NA NA NA 48344.59 48249.56 0.998 78.0 77.5 46499.12 46689.18 98.0 99.0 50000.0 50000.0 57.0 57.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.09999999999999987 1.6428571428571428 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 3 8 KTTVVVTTQK KTTVVVTAQK NetMHC 46710.89 46790.82 1.002 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 48355.445 48395.41 1.001 78.0 78.5 46790.82 46710.89 100.0 99.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 0.5428571428571433 1.4000000000000001 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 5 6 QGIANQDAAQ QGIANEDAAQ NetMHC 46711.4 46770.57 1.001 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 48355.7 48385.285 1.001 78.0 78.0 46770.57 46711.4 99.0 99.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.2285714285714284 -0.08571428571428576 True False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-E*01:01 10 2 9 DAVQGIANQD DAVQGIANED NetMHC 46716.95 46791.33 1.002 PickPocket 57.0 57.0 22 0.5 NA NA NA NA NA NA 48358.475 48395.665 1.001 78.0 78.5 46791.33 46716.95 100.0 99.0 50000.0 50000.0 57.0 57.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.157142857142857 0.7000000000000001 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-E*01:01 10 9 2 PQTDYLTGTD PETDYLTGTD NetMHC 46719.99 46966.32 1.005 PickPocket 57.0 57.0 136 0.25 NA NA NA NA NA NA 48359.995 48483.16 1.003 78.0 78.5 46966.32 46719.99 100.0 99.0 50000.0 50000.0 57.0 57.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.9 -0.5 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-E*01:01 10 2 9 AKTTVVVTTQ AKTTVVVTAQ NetMHC 46755.38 46925.17 1.004 PickPocket 57.0 57.0 96 0.042 NA NA NA NA NA NA 48377.69 48462.585 1.002 78.0 78.5 46925.17 46755.38 100.0 99.0 50000.0 50000.0 57.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.0000000000000002 1.4000000000000001 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 8 NA SAGSTGQGSG NA NetMHC 46772.08 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48386.04 NA NA 78.0 NA NA 46772.08 NA 99.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 5 7, 8, 9, 10 GGRSAGSTGQ GGRSAGQHWA NetMHC 46800.93 46477.98 0.993 PickPocket 57.0 50.0 142 0.768 NA NA NA NA NA NA 48400.465 45433.795 0.939 78.5 74.0 46477.98 46800.93 98.0 100.0 44389.61 50000.0 50.0 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6857142857142857 -0.6857142857142857 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 2 10 TGGGGRSAGS TGGGGRSAGQ NetMHC 46819.68 46560.51 0.994 PickPocket 57.0 57.0 142 0.768 NA NA NA NA NA NA 48409.84 48280.255 0.997 78.5 77.5 46560.51 46819.68 98.0 100.0 50000.0 50000.0 57.0 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.7857142857142857 -0.7285714285714285 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 10 1 HGGVSLSKIE PGGVSLSKIE NetMHC 46821.21 46994.77 1.004 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 48410.605 48497.385 1.002 78.5 78.5 46994.77 46821.21 100.0 100.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.5 0.9428571428571428 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 6 5 GLLHIYGSGG GLLHTYGSGG NetMHC 46854.14 46658.87 0.996 PickPocket 57.0 57.0 120 0.233 NA NA NA NA NA NA 48427.07 48329.435 0.998 78.5 78.0 46658.87 46854.14 99.0 100.0 50000.0 50000.0 57.0 57.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.2857142857142857 0.9714285714285714 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 6 1, 2, 3, 4 SRTLLLAAAG LSRTLLAAAG NetMHC 46856.16 47029.36 1.004 PickPocket 57.0 57.0 76 0.158 NA NA NA NA NA NA 48428.08 48514.68 1.002 78.5 78.5 47029.36 46856.16 100.0 100.0 50000.0 50000.0 57.0 57.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 2.342857142857143 2.342857142857143 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 2 9 KTVTISCTGS KTVTISCTRS NetMHC 46903.33 46427.23 0.99 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 48451.665 48213.615 0.995 78.5 77.0 46427.23 46903.33 97.0 100.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.5142857142857142 1.2285714285714284 False False False 1 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 10 3 8 GGSHVWTHSR GGSHVWTRSR NetMHC 46925.69 47050.75 1.003 PickPocket 57.0 57.0 56 0.071 NA NA NA NA NA NA 48462.845 48525.375 1.001 78.5 78.5 47050.75 46925.69 100.0 100.0 50000.0 50000.0 57.0 57.0 5.CECR2.ENST00000262608.8.missense.535R/H False -1.3000000000000003 -0.31428571428571433 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-E*01:01 10 2 9 SPVKEEEKTQ SPVKEEEKPQ NetMHC 46927.2 47045.65 1.003 PickPocket 57.0 57.0 185 0.038 NA NA NA NA NA NA 48463.6 48522.825 1.001 78.5 78.5 47045.65 46927.2 100.0 100.0 50000.0 50000.0 57.0 57.0 12.NEFH.ENST00000310624.6.missense.830P/T False -3.2142857142857144 -1.8 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 12 1 PLLLLLGASG LLLLLLGASG NetMHC 46938.88 46940.91 1.0 PickPocket 57.0 57.0 101 0.891 NA NA NA NA NA NA 48469.44 48470.455 1.0 78.5 78.5 46940.91 46938.88 100.0 100.0 50000.0 50000.0 57.0 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 1.6571428571428568 2.9142857142857146 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 13 NA GQGSGEKAGC NA NetMHC 46983.59 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48491.795 NA NA 78.5 NA NA 46983.59 NA 100.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6714285714285715 -0.6714285714285715 False True False 1 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 10 5 7, 10 LSRTLLLAAA LSRTLLAAAG NetMHC 46989.19 47029.36 1.001 PickPocket 57.0 57.0 76 0.158 NA NA NA NA NA NA 48494.595 48514.68 1.0 78.5 78.5 47029.36 46989.19 100.0 100.0 50000.0 50000.0 57.0 57.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 2.3000000000000003 2.3000000000000003 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 9 NA AGSTGQGSGE NA NetMHC 47084.35 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48542.175 NA NA 78.5 NA NA 47084.35 NA 100.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.3857142857142857 -0.6285714285714287 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 10 10 1 APTTVIYEDN SPTTVIYEDN NetMHC 47145.52 47266.07 1.003 PickPocket 57.0 57.0 7 0.571 NA NA NA NA NA NA 48572.76 48633.035 1.001 78.5 78.5 47266.07 47145.52 100.0 100.0 50000.0 50000.0 57.0 57.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.5428571428571428 0.8857142857142858 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 7 4 AGNLFNCECD AGNPFNCECD NetMHC 47175.62 45625.46 0.967 PickPocket 57.0 57.0 303 0.135 NA NA NA NA NA NA 48587.81 47812.73 0.984 78.5 73.5 45625.46 47175.62 90.0 100.0 50000.0 50000.0 57.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.5 False False False 2 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 5 6 YGLLHIYGSG YGLLHTYGSG NetMHC 47180.22 46813.61 0.992 PickPocket 57.0 57.0 120 0.233 NA NA NA NA NA NA 48590.11 48406.805 0.996 78.5 78.5 46813.61 47180.22 100.0 100.0 50000.0 50000.0 57.0 57.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.3142857142857142 0.9714285714285714 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-E*01:01 10 6 5 LAGNLFNCEC LAGNPFNCEC NetMHC 47185.85 45731.25 0.969 PickPocket 57.0 57.0 303 0.135 NA NA NA NA NA NA 48592.925 47865.625 0.985 78.5 74.0 45731.25 47185.85 91.0 100.0 50000.0 50000.0 57.0 57.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.6857142857142856 False True False 2 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-E*01:01 10 1 10 GKTVTISCTG GKTVTISCTR NetMHC 47197.08 47039.55 0.997 PickPocket 57.0 57.0 5 1.0 NA NA NA NA NA NA 48598.54 48519.775 0.998 78.5 78.5 47039.55 47197.08 100.0 100.0 50000.0 50000.0 57.0 57.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 1.2285714285714284 1.2285714285714284 False False False 1 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-E*01:01 10 8 3 LNNLLTEEED LNHLLTEEED NetMHC 47229.26 47089.97 0.997 PickPocket 57.0 57.0 30 0.1 NA NA NA NA NA NA 48614.63 48544.985 0.999 78.5 78.5 47089.97 47229.26 100.0 100.0 50000.0 50000.0 57.0 57.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.02857142857142847 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 10 10 NA GSTGQGSGEK NA NetMHC 47242.55 NA NA PickPocket 57.0 NA 142 0.768 NA NA NA NA NA NA 48621.275 NA NA 78.5 NA NA 47242.55 NA 100.0 NA 50000.0 NA 57.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.842857142857143 -1.0000000000000002 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 3 8 HEDLIGKHGG HEDLIGKPGG NetMHC 47290.1 46578.17 0.985 PickPocket 57.0 52.0 140 0.179 NA NA NA NA NA NA 48645.05 45969.41 0.945 78.5 75.0 46578.17 47290.1 98.0 100.0 45360.65 50000.0 52.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H False -3.172065784643304e-17 -3.172065784643304e-17 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-E*01:01 10 4 7 SYGLLHIYGS SYGLLHTYGS PickPocket 42509.45 50000.0 1.176 PickPocket 48.0 57.0 120 0.233 NA NA NA NA NA NA 44914.875 48439.235 1.078 74.0 78.5 46878.47 47320.3 100.0 100.0 50000.0 42509.45 57.0 48.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.914285714285714 0.9714285714285714 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 10 2 9 HHEDLIGKHG HHEDLIGKPG NetMHC 47320.82 47279.36 0.999 PickPocket 57.0 57.0 140 0.179 NA NA NA NA NA NA 48660.41 48639.68 1.0 78.5 78.5 47279.36 47320.82 100.0 100.0 50000.0 50000.0 57.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.44285714285714295 -0.44285714285714295 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 10 11 1, 2 LPLLLLLGAS PLLLLLLGAS NetMHC 47327.99 47032.43 0.994 PickPocket 57.0 57.0 101 0.891 NA NA NA NA NA NA 48663.995 48516.215 0.997 78.5 78.5 47032.43 47327.99 100.0 100.0 50000.0 50000.0 57.0 57.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.2571428571428567 3.028571428571429 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 5 5 KFNPQTDYL KFNPETDYL PickPocket 1262.76 1318.61 1.044 PickPocket 0.5 0.6 136 0.25 NA NA NA NA NA NA 1262.76 1318.61 1.044 0.5 0.6 NA NA NA NA 1318.61 1262.76 0.6 0.5 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.4714285714285715 -1.4714285714285715 False False False 0 False 1 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 8 2 HIYGSGGYA HTYGSGGYA PickPocket 1672.99 1584.89 0.947 PickPocket 1.0 0.9 120 0.233 NA NA NA NA NA NA 1672.99 1584.89 0.947 1.0 0.9 NA NA NA NA 1584.89 1672.99 0.9 1.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.39999999999999997 -0.014285714285714266 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 1 9 WYQQRPGSA WYQQRPGSS PickPocket 2781.92 3567.97 1.283 PickPocket 2.7 4.3 7 0.571 NA NA NA NA NA NA 2781.92 3567.97 1.283 2.7 4.3 NA NA NA NA 3567.97 2781.92 4.3 2.7 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.7857142857142858 -1.7857142857142858 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 8 2 LVYCLQKCN LAYCLQKCN PickPocket 3099.81 6399.79 2.065 PickPocket 3.3 12.0 113 0.053 NA NA NA NA NA NA 3099.81 6399.79 2.065 3.3 12.0 NA NA NA NA 6399.79 3099.81 12.0 3.3 6.USP18.ENST00000215794.7.missense.124A/V False -0.4857142857142857 0.7999999999999999 False False False 2 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 1 9 MVCELAGNL MVCELAGNP PickPocket 3454.02 10191.11 2.951 PickPocket 4.1 21.0 303 0.135 NA NA NA NA NA NA 3454.02 10191.11 2.951 4.1 21.0 NA NA NA NA 10191.11 3454.02 21.0 4.1 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6428571428571427 1.4714285714285713 False False False 1 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 2 8 YSYGLLHIY YSYGLLHTY PickPocket 3766.31 2842.78 0.755 PickPocket 4.7 2.8 120 0.233 NA NA NA NA NA NA 3766.31 2842.78 0.755 4.7 2.8 NA NA NA NA 2842.78 3766.31 2.8 4.7 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.8428571428571427 0.9142857142857143 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 8 2 AFTRLTSEL ASTRLTSEL PickPocket 3807.28 8387.64 2.203 PickPocket 4.8 16.0 171 0.959 NA NA NA NA NA NA 3807.28 8387.64 2.203 4.8 16.0 NA NA NA NA 8387.64 3807.28 16.0 4.8 22.PANX2.ENST00000395842.2.missense.147S/F False -0.3714285714285715 0.24285714285714272 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 2 9 ATLSRTLLL ATLSRTLLA PickPocket 4478.16 9245.51 2.065 PickPocket 6.1 19.0 76 0.158 NA NA NA NA NA NA 4478.16 9245.51 2.065 6.1 19.0 NA NA NA NA 9245.51 4478.16 19.0 6.1 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.3142857142857143 1.3142857142857143 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 6 4 LLHIYGSGG LLHTYGSGG PickPocket 4526.88 3932.89 0.869 PickPocket 6.3 5.0 120 0.233 NA NA NA NA NA NA 4526.88 3932.89 0.869 6.3 5.0 NA NA NA NA 3932.89 4526.88 5.0 6.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.2857142857142857 0.914285714285714 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 9 1 RSRTYDMDV HSRTYDMDV PickPocket 4576.12 7609.38 1.663 PickPocket 6.3 15.0 210 0.686 NA NA NA NA NA NA 4576.12 7609.38 1.663 6.3 15.0 NA NA NA NA 7609.38 4576.12 15.0 6.3 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 6 6 LLPLLPLLL LLPLLLLLL PickPocket 4778.52 4830.5 1.011 PickPocket 6.8 6.9 101 0.891 NA NA NA NA NA NA 4778.52 4830.5 1.011 6.8 6.9 NA NA NA NA 4830.5 4778.52 6.9 6.8 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 2 8 SVNEALNNL SVNEALNHL PickPocket 4989.87 7775.84 1.558 PickPocket 7.3 15.0 30 0.1 NA NA NA NA NA NA 4989.87 7775.84 1.558 7.3 15.0 NA NA NA NA 7775.84 4989.87 15.0 7.3 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 1 9 YYSYGLLHI YYSYGLLHT PickPocket 5382.48 8664.37 1.61 PickPocket 8.0 17.0 120 0.233 NA NA NA NA NA NA 5382.48 8664.37 1.61 8.0 17.0 NA NA NA NA 8664.37 5382.48 17.0 8.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9142857142857143 0.9142857142857143 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 7 3 WTHSRDPEG WTRSRDPEG PickPocket 5500.22 19932.31 3.624 PickPocket 8.4 40.0 56 0.071 NA NA NA NA NA NA 5500.22 19932.31 3.624 8.4 40.0 NA NA NA NA 19932.31 5500.22 40.0 8.4 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5 -2.1714285714285717 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 3 7 SYGLLHIYG SYGLLHTYG PickPocket 5620.54 5743.49 1.022 PickPocket 8.7 9.0 120 0.233 NA NA NA NA NA NA 5620.54 5743.49 1.022 8.7 9.0 NA NA NA NA 5743.49 5620.54 9.0 8.7 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9714285714285714 0.9714285714285714 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 9 1 IYGSGGYAL TYGSGGYAL PickPocket 5620.54 6539.79 1.164 PickPocket 8.7 12.0 120 0.233 NA NA NA NA NA NA 5620.54 6539.79 1.164 8.7 12.0 NA NA NA NA 6539.79 5620.54 12.0 8.7 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.32857142857142857 0.32857142857142857 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 8 2 GYESRVEPP GSESRVEPP PickPocket 5620.54 22209.93 3.952 PickPocket 8.7 44.0 116 0.043 NA NA NA NA NA NA 5620.54 22209.93 3.952 8.7 44.0 NA NA NA NA 22209.93 5620.54 44.0 8.7 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.6142857142857143 -1.4000000000000001 False False True 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 7 3 ANQDAAQGI ANEDAAQGI PickPocket 5681.68 9654.43 1.699 PickPocket 8.8 20.0 22 0.5 NA NA NA NA NA NA 5681.68 9654.43 1.699 8.8 20.0 NA NA NA NA 9654.43 5681.68 20.0 8.8 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 -0.4000000000000001 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 9 1 VYCLQKCNV AYCLQKCNV PickPocket 5932.98 4830.5 0.814 PickPocket 9.4 6.9 113 0.053 NA NA NA NA NA NA 5932.98 4830.5 0.814 9.4 6.9 NA NA NA NA 4830.5 5932.98 6.9 9.4 6.USP18.ENST00000215794.7.missense.124A/V False 0.3 0.6142857142857141 False False False 2 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 3 7 GSHVWTHSR GSHVWTRSR PickPocket 6195.39 6399.79 1.033 PickPocket 9.9 12.0 56 0.071 NA NA NA NA NA NA 6195.39 6399.79 1.033 9.9 12.0 NA NA NA NA 6399.79 6195.39 12.0 9.9 5.CECR2.ENST00000262608.8.missense.535R/H False -1.3000000000000003 -0.7142857142857143 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 8 2 NLFNCECDL NPFNCECDL PickPocket 6195.39 20813.9 3.36 PickPocket 9.9 42.0 303 0.135 NA NA NA NA NA NA 6195.39 20813.9 3.36 9.9 42.0 NA NA NA NA 20813.9 6195.39 42.0 9.9 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 True 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 4 6 RPLELVYCL RPLELAYCL PickPocket 6399.79 6903.33 1.079 PickPocket 12.0 13.0 113 0.053 NA NA NA NA NA NA 6399.79 6903.33 1.079 12.0 13.0 NA NA NA NA 6903.33 6399.79 13.0 12.0 6.USP18.ENST00000215794.7.missense.124A/V False 1.9000000000000001 1.9000000000000001 False False False 1 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 3 7 RTEASGYES RTEASGSES PickPocket 6399.79 5267.25 0.823 PickPocket 12.0 7.9 116 0.043 NA NA NA NA NA NA 6399.79 5267.25 0.823 12.0 7.9 NA NA NA NA 5267.25 6399.79 7.9 12.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.2142857142857142 -1.2 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 7 3 SGYESRVEP SGSESRVEP PickPocket 7287.08 50000.0 6.861 PickPocket 14.0 73.0 116 0.043 NA NA NA NA NA NA 7287.08 50000.0 6.861 14.0 73.0 NA NA NA NA 50000.0 7287.08 73.0 14.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.5714285714285712 -1.0142857142857145 False False True 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 8 2 KTQEVKVKE KPQEVKVKE PickPocket 7366.35 25842.4 3.508 PickPocket 14.0 50.0 185 0.038 NA NA NA NA NA NA 7366.35 25842.4 3.508 14.0 50.0 NA NA NA NA 25842.4 7366.35 50.0 14.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.4142857142857141 -1.014285714285714 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 2 8 AVQGIANQD AVQGIANED PickPocket 7609.38 5743.49 0.755 PickPocket 15.0 9.0 22 0.5 NA NA NA NA NA NA 7609.38 5743.49 0.755 15.0 9.0 NA NA NA NA 5743.49 7609.38 9.0 15.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.157142857142857 0.7000000000000001 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 3 7 VNEALNNLL VNEALNHLL PickPocket 7775.84 8032.38 1.033 PickPocket 15.0 16.0 30 0.1 NA NA NA NA NA NA 7775.84 8032.38 1.033 15.0 16.0 NA NA NA NA 8032.38 7775.84 16.0 15.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.3857142857142856 0.3857142857142856 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 9 1 LFNCECDLF PFNCECDLF PickPocket 7860.43 21500.59 2.735 PickPocket 15.0 43.0 303 0.135 NA NA NA NA NA NA 7860.43 21500.59 2.735 15.0 43.0 NA NA NA NA 21500.59 7860.43 43.0 15.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 5 5 HVWTHSRDP HVWTRSRDP PickPocket 8119.76 11112.54 1.369 PickPocket 16.0 23.0 56 0.071 NA NA NA NA NA NA 8119.76 11112.54 1.369 16.0 23.0 NA NA NA NA 11112.54 8119.76 23.0 16.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1714285714285717 -1.3000000000000003 False False True 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 6 1, 2, 3 RTLLLAAAG SRTLLAAAG PickPocket 8478.89 50000.0 5.897 PickPocket 17.0 73.0 76 0.158 NA NA NA NA NA NA 8478.89 50000.0 5.897 17.0 73.0 NA NA NA NA 50000.0 8478.89 73.0 17.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 2.342857142857143 2.342857142857143 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 1 9 YQPCDDMDY YQPCDDMDC PickPocket 8571.13 8478.89 0.989 PickPocket 17.0 17.0 92 0.043 NA NA NA NA NA NA 8571.13 8478.89 0.989 17.0 17.0 NA NA NA NA 8478.89 8571.13 17.0 17.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 5 5 EFLAFTRLT EFLASTRLT PickPocket 9146.01 11479.16 1.255 PickPocket 18.0 24.0 171 0.959 NA NA NA NA NA NA 9146.01 11479.16 1.255 18.0 24.0 NA NA NA NA 11479.16 9146.01 24.0 18.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.8999999999999997 1.4000000000000001 True False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 4 6 KEEEKTQEV KEEEKPQEV PickPocket 9346.08 11355.63 1.215 PickPocket 19.0 24.0 185 0.038 NA NA NA NA NA NA 9346.08 11355.63 1.215 19.0 24.0 NA NA NA NA 11355.63 9346.08 24.0 19.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.0571428571428574 -2.0571428571428574 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 1 9 KTVTISCTG KTVTISCTR PickPocket 9447.76 15208.39 1.61 PickPocket 19.0 31.0 5 1.0 NA NA NA NA NA NA 9447.76 15208.39 1.61 19.0 31.0 NA NA NA NA 15208.39 9447.76 31.0 19.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 1.2285714285714284 1.2285714285714284 False False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 3 7 GWEFLAFTR GWEFLASTR PickPocket 9654.43 7775.84 0.805 PickPocket 20.0 15.0 171 0.959 NA NA NA NA NA NA 9654.43 7775.84 0.805 20.0 15.0 NA NA NA NA 7775.84 9654.43 15.0 20.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.35714285714285704 0.9142857142857143 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 8 2 DYLSDRCKI DCLSDRCKI PickPocket 9865.62 50000.0 5.068 PickPocket 20.0 73.0 92 0.043 NA NA NA NA NA NA 9865.62 50000.0 5.068 20.0 73.0 NA NA NA NA 50000.0 9865.62 73.0 20.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.27142857142857146 -0.27142857142857146 False False False 1 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 8 2 SAPTTVIYE SSPTTVIYE PickPocket 9972.95 5620.54 0.564 PickPocket 21.0 8.7 7 0.571 NA NA NA NA NA NA 9972.95 5620.54 0.564 21.0 8.7 NA NA NA NA 5620.54 9972.95 8.7 21.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.12857142857142861 0.9571428571428572 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 2 8 LCQRAKVEM LCQRAKVAM PickPocket 9972.95 15710.15 1.575 PickPocket 21.0 33.0 113 0.044 NA NA NA NA NA NA 9972.95 15710.15 1.575 21.0 33.0 NA NA NA NA 15710.15 9972.95 33.0 21.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.0714285714285712 0.0571428571428572 False False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 7 3 KVEMSHFEP KVAMSHFEP PickPocket 9972.95 31060.99 3.115 PickPocket 21.0 56.0 113 0.044 NA NA NA NA NA NA 9972.95 31060.99 3.115 21.0 56.0 NA NA NA NA 31060.99 9972.95 56.0 21.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.1285714285714286 -0.3000000000000001 False False True 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 5 5 GLLHIYGSG GLLHTYGSG PickPocket 10414.04 12117.27 1.164 PickPocket 22.0 25.0 120 0.233 NA NA NA NA NA NA 10414.04 12117.27 1.164 22.0 25.0 NA NA NA NA 12117.27 10414.04 25.0 22.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.3142857142857142 0.9714285714285714 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 5 7 PLLPLLPLL PLLPLLLLL PickPocket 10527.33 12653.21 1.202 PickPocket 22.0 26.0 101 0.891 NA NA NA NA NA NA 10527.33 12653.21 1.202 22.0 26.0 NA NA NA NA 12653.21 10527.33 26.0 22.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 7 3 LVRSRTYDM LVHSRTYDM PickPocket 10527.33 2904.96 0.276 PickPocket 22.0 2.9 210 0.686 NA NA NA NA NA NA 10527.33 2904.96 0.276 22.0 2.9 NA NA NA NA 2904.96 10527.33 2.9 22.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.9142857142857144 -0.5428571428571428 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 2 8 KTTVVVTTQ KTTVVVTAQ PickPocket 10874.65 16763.86 1.542 PickPocket 23.0 34.0 96 0.042 NA NA NA NA NA NA 10874.65 16763.86 1.542 23.0 34.0 NA NA NA NA 16763.86 10874.65 34.0 23.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.0000000000000002 1.4000000000000001 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 7 3 MDYLSDRCK MDCLSDRCK PickPocket 11355.63 50000.0 4.403 PickPocket 24.0 73.0 92 0.043 NA NA NA NA NA NA 11355.63 50000.0 4.403 24.0 73.0 NA NA NA NA 50000.0 11355.63 73.0 24.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.0999999999999999 -1.042857142857143 False False False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 9 1 QTDYLTGTD ETDYLTGTD PickPocket 11355.63 18882.64 1.663 PickPocket 24.0 38.0 136 0.25 NA NA NA NA NA NA 11355.63 18882.64 1.663 24.0 38.0 NA NA NA NA 18882.64 11355.63 38.0 24.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.9 -0.5 True False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 2 8 LGWEFLAFT LGWEFLAST PickPocket 11730.27 17316.93 1.476 PickPocket 24.0 36.0 171 0.959 NA NA NA NA NA NA 11730.27 17316.93 1.476 24.0 36.0 NA NA NA NA 17316.93 11730.27 36.0 24.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.8714285714285712 1.0571428571428572 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 2 8 GTLKFNPQT GTLKFNPET PickPocket 11986.87 9047.59 0.755 PickPocket 25.0 18.0 136 0.25 NA NA NA NA NA NA 11986.87 9047.59 0.755 25.0 18.0 NA NA NA NA 9047.59 11986.87 18.0 25.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.942857142857143 -0.5000000000000001 False False False 0 False 1 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 8 1 LLLAAAGGS TLLAAAGGS PickPocket 12517.05 12653.21 1.011 PickPocket 26.0 26.0 76 0.158 NA NA NA NA NA NA 12517.05 12653.21 1.011 26.0 26.0 NA NA NA NA 12653.21 12517.05 26.0 26.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.0857142857142856 2.342857142857143 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 8 1, 3, 4 PLLPLLLLL LLPLLLLLL PickPocket 12653.21 4830.5 0.382 PickPocket 26.0 6.9 101 0.891 NA NA NA NA NA NA 12653.21 4830.5 0.382 26.0 6.9 NA NA NA NA 4830.5 12653.21 6.9 26.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 3.028571428571429 3.028571428571429 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 9 2, 3 LLPLLLLLG LPLLLLLLG PickPocket 12653.21 50000.0 3.952 PickPocket 26.0 73.0 101 0.891 NA NA NA NA NA NA 12653.21 50000.0 3.952 26.0 73.0 NA NA NA NA 50000.0 12653.21 73.0 26.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.4285714285714293 3.028571428571429 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 1 9 KSVNEALNN KSVNEALNH PickPocket 12930.01 15710.15 1.215 PickPocket 27.0 33.0 30 0.1 NA NA NA NA NA NA 12930.01 15710.15 1.215 27.0 33.0 NA NA NA NA 15710.15 12930.01 33.0 27.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6 -0.21428571428571427 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 8 2 VEMSHFEPN VAMSHFEPN PickPocket 13070.67 9865.62 0.755 PickPocket 27.0 20.0 113 0.044 NA NA NA NA NA NA 13070.67 9865.62 0.755 27.0 20.0 NA NA NA NA 9865.62 13070.67 20.0 27.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.1285714285714286 -0.3000000000000001 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 19 NA AGCPWSGTG NA PickPocket 13501.89 NA NA PickPocket 28.0 NA 142 0.768 NA NA NA NA NA NA 13501.89 NA NA 28.0 NA NA NA NA NA NA 13501.89 NA 28.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.3285714285714286 0.02857142857142855 False False False 1 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 2 8 AVRPLELVY AVRPLELAY PickPocket 14099.07 23444.56 1.663 PickPocket 29.0 46.0 113 0.053 NA NA NA NA NA NA 14099.07 23444.56 1.663 29.0 46.0 NA NA NA NA 23444.56 14099.07 46.0 29.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.1285714285714286 0.9142857142857144 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 7 3 GNLFNCECD GNPFNCECD PickPocket 14252.45 10874.65 0.763 PickPocket 29.0 23.0 303 0.135 NA NA NA NA NA NA 14252.45 10874.65 0.763 29.0 23.0 NA NA NA NA 10874.65 14252.45 23.0 29.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 2 8 SLFGALVRS SLFGALVHS PickPocket 14564.23 12382.34 0.85 PickPocket 30.0 26.0 210 0.686 NA NA NA NA NA NA 14564.23 12382.34 0.85 30.0 26.0 NA NA NA NA 12382.34 14564.23 26.0 30.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False 0.9857142857142857 2.1714285714285713 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 6 4 ALNNLLTEE ALNHLLTEE PickPocket 14722.66 15710.15 1.067 PickPocket 31.0 33.0 30 0.1 NA NA NA NA NA NA 14722.66 15710.15 1.067 31.0 33.0 NA NA NA NA 15710.15 14722.66 33.0 31.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.7857142857142856 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 6 4 VWTHSRDPE VWTRSRDPE PickPocket 15044.73 16228.45 1.079 PickPocket 31.0 34.0 56 0.071 NA NA NA NA NA NA 15044.73 16228.45 1.079 31.0 34.0 NA NA NA NA 16228.45 15044.73 34.0 31.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5428571428571423 -1.3428571428571427 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 7 1, 2 TLLLAAAGG RTLLAAAGG PickPocket 16053.81 6128.72 0.382 PickPocket 33.0 9.7 76 0.158 NA NA NA NA NA NA 16053.81 6128.72 0.382 33.0 9.7 NA NA NA NA 6128.72 16053.81 9.7 33.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.742857142857143 2.342857142857143 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 2 8 YQQRPGSAP YQQRPGSSP PickPocket 16763.86 12249.09 0.731 PickPocket 34.0 25.0 7 0.571 NA NA NA NA NA NA 16763.86 12249.09 0.731 34.0 25.0 NA NA NA NA 12249.09 16763.86 25.0 34.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.5142857142857142 -1.5142857142857142 False False True 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 9 1 YLSDRCKIL CLSDRCKIL PickPocket 16763.86 21734.48 1.297 PickPocket 34.0 44.0 92 0.043 NA NA NA NA NA NA 16763.86 21734.48 1.297 34.0 44.0 NA NA NA NA 21734.48 16763.86 44.0 34.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.27142857142857163 -0.27142857142857146 False False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 20 NA GCPWSGTGQ NA PickPocket 17130.58 NA NA PickPocket 35.0 NA 142 0.768 NA NA NA NA NA NA 17130.58 NA NA 35.0 NA NA NA NA NA NA 17130.58 NA 35.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.1857142857142857 -0.32857142857142857 False False False 1 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 4 6 VSPEPARPP VSPEPPRPP PickPocket 18082.85 17316.93 0.958 PickPocket 37.0 36.0 245 0.486 NA NA NA NA NA NA 18082.85 17316.93 0.958 37.0 36.0 NA NA NA NA 17316.93 18082.85 36.0 37.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.7999999999999996 -0.8571428571428571 False False True 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 5 5 ISCTGSSGS ISCTRSSGS PickPocket 18279.56 23192.26 1.269 PickPocket 37.0 46.0 5 1.0 NA NA NA NA NA NA 18279.56 23192.26 1.269 37.0 46.0 NA NA NA NA 23192.26 18279.56 46.0 37.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.20000000000000004 0.5 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 3 7 VTISCTGSS VTISCTRSS PickPocket 18478.42 18882.64 1.022 PickPocket 38.0 38.0 5 1.0 NA NA NA NA NA NA 18478.42 18882.64 1.022 38.0 38.0 NA NA NA NA 18882.64 18478.42 38.0 38.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.5 1.2285714285714284 False False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 1 9 ALGWEFLAF ALGWEFLAS PickPocket 18882.64 36141.06 1.914 PickPocket 38.0 62.0 171 0.959 NA NA NA NA NA NA 18882.64 36141.06 1.914 38.0 62.0 NA NA NA NA 36141.06 18882.64 62.0 38.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.9142857142857143 1.0571428571428572 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 6 4 FNPQTDYLT FNPETDYLT PickPocket 19295.7 17505.31 0.907 PickPocket 39.0 36.0 136 0.25 NA NA NA NA NA NA 19295.7 17505.31 0.907 39.0 36.0 NA NA NA NA 17505.31 19295.7 36.0 39.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.0714285714285716 -1.0714285714285716 False False False 0 False 1 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 6 4 SCTGSSGSI SCTRSSGSI PickPocket 19505.61 23192.26 1.189 PickPocket 40.0 46.0 5 1.0 NA NA NA NA NA NA 19505.61 23192.26 1.189 40.0 46.0 NA NA NA NA 23192.26 19505.61 46.0 40.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.08571428571428566 0.08571428571428566 False False False 1 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 1 9 VSLFGALVR VSLFGALVH PickPocket 19505.61 13501.89 0.692 PickPocket 40.0 28.0 210 0.686 NA NA NA NA NA NA 19505.61 13501.89 0.692 40.0 28.0 NA NA NA NA 13501.89 19505.61 28.0 40.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False 1.6428571428571428 2.1714285714285713 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 3 7 QQRPGSAPT QQRPGSSPT PickPocket 19717.81 19932.31 1.011 PickPocket 40.0 40.0 7 0.571 NA NA NA NA NA NA 19717.81 19932.31 1.011 40.0 40.0 NA NA NA NA 19932.31 19717.81 40.0 40.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.1142857142857143 -1.1142857142857143 True False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 2 8 VCELAGNLF VCELAGNPF PickPocket 19717.81 17316.93 0.878 PickPocket 40.0 36.0 303 0.135 NA NA NA NA NA NA 19717.81 17316.93 0.878 40.0 36.0 NA NA NA NA 17316.93 19717.81 36.0 40.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6857142857142856 0.7000000000000001 False False False 1 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 9 1 TQEVKVKEP PQEVKVKEP PickPocket 20149.14 50000.0 2.481 PickPocket 41.0 73.0 185 0.038 NA NA NA NA NA NA 20149.14 50000.0 2.481 41.0 73.0 NA NA NA NA 50000.0 20149.14 73.0 41.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.1428571428571428 -1.0142857142857142 False False True 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 9 1 NLLTEEEDY HLLTEEEDY PickPocket 20368.33 10527.33 0.517 PickPocket 41.0 22.0 30 0.1 NA NA NA NA NA NA 20368.33 10527.33 0.517 41.0 22.0 NA NA NA NA 10527.33 20368.33 22.0 41.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.742857142857143 -1.0142857142857145 False False False 0 True 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 3 7 CELAGNLFN CELAGNPFN PickPocket 20813.9 17316.93 0.832 PickPocket 42.0 36.0 303 0.135 NA NA NA NA NA NA 20813.9 17316.93 0.832 42.0 36.0 NA NA NA NA 17316.93 20813.9 36.0 42.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6857142857142856 0.6857142857142856 True False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 11 NA TGQGSGEKA NA PickPocket 21040.32 NA NA PickPocket 42.0 NA 142 0.768 NA NA NA NA NA NA 21040.32 NA NA 42.0 NA NA NA NA NA NA 21040.32 NA 42.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.5285714285714287 -1.3857142857142857 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 9 1 FTRLTSELN STRLTSELN PickPocket 21040.32 17316.93 0.823 PickPocket 42.0 36.0 171 0.959 NA NA NA NA NA NA 21040.32 17316.93 0.823 42.0 36.0 NA NA NA NA 17316.93 21040.32 36.0 42.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.7714285714285715 -0.3714285714285715 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 6 NA RSAGSTGQG NA PickPocket 21734.48 NA NA PickPocket 44.0 NA 142 0.768 NA NA NA NA NA NA 21734.48 NA NA 44.0 NA NA NA NA NA NA 21734.48 NA 44.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6285714285714287 -0.6285714285714287 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 9 1 ARPPQQPVP PRPPQQPVP PickPocket 22209.93 50000.0 2.251 PickPocket 44.0 73.0 245 0.486 NA NA NA NA NA NA 22209.93 50000.0 2.251 44.0 73.0 NA NA NA NA 50000.0 22209.93 73.0 44.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 1 9 VLCQRAKVE VLCQRAKVA PickPocket 22209.93 19088.05 0.859 PickPocket 44.0 39.0 113 0.044 NA NA NA NA NA NA 22209.93 19088.05 0.859 44.0 39.0 NA NA NA NA 19088.05 22209.93 39.0 44.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.9857142857142857 0.0571428571428572 False False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 4 6 WEFLAFTRL WEFLASTRL PickPocket 22209.93 25017.04 1.126 PickPocket 44.0 49.0 171 0.959 NA NA NA NA NA NA 22209.93 25017.04 1.126 44.0 49.0 NA NA NA NA 25017.04 22209.93 49.0 44.0 22.PANX2.ENST00000395842.2.missense.147S/F False 1.4000000000000001 1.4000000000000001 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 6 4 DMDYLSDRC DMDCLSDRC PickPocket 22451.54 23957.42 1.067 PickPocket 45.0 47.0 92 0.043 NA NA NA NA NA NA 22451.54 23957.42 1.067 45.0 47.0 NA NA NA NA 23957.42 22451.54 47.0 45.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.042857142857143 -0.9857142857142857 False True False 1 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 8 2 NQDAAQGIA NEDAAQGIA PickPocket 22695.78 50000.0 2.203 PickPocket 45.0 73.0 22 0.5 NA NA NA NA NA NA 22695.78 50000.0 2.203 45.0 73.0 NA NA NA NA 50000.0 22695.78 73.0 45.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False 0.35714285714285715 0.35714285714285715 False False False 0 True 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 6 4 IGKHGGVSL IGKPGGVSL PickPocket 22695.78 19295.7 0.85 PickPocket 45.0 39.0 140 0.179 NA NA NA NA NA NA 22695.78 19295.7 0.85 45.0 39.0 NA NA NA NA 19295.7 22695.78 39.0 45.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.10000000000000002 0.05714285714285713 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 7 3 GKHGGVSLS GKPGGVSLS PickPocket 22695.78 38984.65 1.718 PickPocket 45.0 65.0 140 0.179 NA NA NA NA NA NA 22695.78 38984.65 1.718 45.0 65.0 NA NA NA NA 38984.65 22695.78 65.0 45.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.3428571428571429 0.3428571428571429 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 2 8 QPCDDMDYL QPCDDMDCL PickPocket 22695.78 27875.69 1.228 PickPocket 45.0 53.0 92 0.043 NA NA NA NA NA NA 22695.78 27875.69 1.228 45.0 53.0 NA NA NA NA 27875.69 22695.78 53.0 45.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.5142857142857142 -0.5142857142857142 True False False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 3 7 TLKFNPQTD TLKFNPETD PickPocket 22695.78 24218.04 1.067 PickPocket 45.0 47.0 136 0.25 NA NA NA NA NA NA 22695.78 24218.04 1.067 45.0 47.0 NA NA NA NA 24218.04 22695.78 47.0 45.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.9857142857142855 -0.942857142857143 False False False 0 False 1 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 1 9 KAVRPLELV KAVRPLELA PickPocket 23192.26 30396.07 1.311 PickPocket 46.0 56.0 113 0.053 NA NA NA NA NA NA 23192.26 30396.07 1.311 46.0 56.0 NA NA NA NA 30396.07 23192.26 56.0 46.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.9142857142857144 0.9142857142857144 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 6 4 ALVRSRTYD ALVHSRTYD PickPocket 23192.26 21500.59 0.927 PickPocket 46.0 43.0 210 0.686 NA NA NA NA NA NA 23192.26 21500.59 0.927 46.0 43.0 NA NA NA NA 21500.59 23192.26 43.0 46.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.5857142857142856 -0.09999999999999987 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 4 6 YGLLHIYGS YGLLHTYGS PickPocket 24747.82 18679.43 0.755 PickPocket 48.0 38.0 120 0.233 NA NA NA NA NA NA 24747.82 18679.43 0.755 48.0 38.0 NA NA NA NA 18679.43 24747.82 38.0 48.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.914285714285714 0.9714285714285714 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 9 1 HSRDPEGSS RSRDPEGSS PickPocket 25017.04 15044.73 0.601 PickPocket 49.0 31.0 56 0.071 NA NA NA NA NA NA 25017.04 15044.73 0.601 49.0 31.0 NA NA NA NA 15044.73 25017.04 31.0 49.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 4 6 QRPGSAPTT QRPGSSPTT PickPocket 25017.04 23192.26 0.927 PickPocket 49.0 46.0 7 0.571 NA NA NA NA NA NA 25017.04 23192.26 0.927 49.0 46.0 NA NA NA NA 23192.26 25017.04 46.0 49.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.5714285714285714 -0.5714285714285714 True False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 7 3 LNNLLTEEE LNHLLTEEE PickPocket 25289.19 6903.33 0.273 PickPocket 49.0 13.0 30 0.1 NA NA NA NA NA NA 25289.19 6903.33 0.273 49.0 13.0 NA NA NA NA 6903.33 25289.19 13.0 49.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.02857142857142847 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 5 5 RPGSAPTTV RPGSSPTTV PickPocket 25289.19 26407.71 1.044 PickPocket 49.0 51.0 7 0.571 NA NA NA NA NA NA 25289.19 26407.71 1.044 49.0 51.0 NA NA NA NA 26407.71 25289.19 51.0 49.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.2571428571428571 0.2571428571428571 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 15 NA SGEKAGCPW NA PickPocket 25289.19 NA NA PickPocket 49.0 NA 142 0.768 NA NA NA NA NA NA 25289.19 NA NA 49.0 NA NA NA NA NA NA 25289.19 NA 49.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8571428571428574 -0.6714285714285715 False False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 5 5 RAKVEMSHF RAKVAMSHF PickPocket 25289.19 21970.92 0.869 PickPocket 49.0 44.0 113 0.044 NA NA NA NA NA NA 25289.19 21970.92 0.869 49.0 44.0 NA NA NA NA 21970.92 25289.19 44.0 49.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.35714285714285715 -0.35714285714285715 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 18 NA KAGCPWSGT NA PickPocket 25564.3 NA NA PickPocket 50.0 NA 142 0.768 NA NA NA NA NA NA 25564.3 NA NA 50.0 NA NA NA NA NA NA 25564.3 NA 50.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.32857142857142857 0.02857142857142855 False False False 1 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 9 7 3 LHIYGSGGY LHTYGSGGY PickPocket 25564.3 29108.61 1.139 PickPocket 50.0 54.0 120 0.233 NA NA NA NA NA NA 25564.3 29108.61 1.139 50.0 54.0 NA NA NA NA 29108.61 25564.3 54.0 50.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.014285714285714266 0.3142857142857142 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 3 7 LFGALVRSR LFGALVHSR PickPocket 25842.4 25017.04 0.968 PickPocket 50.0 49.0 210 0.686 NA NA NA NA NA NA 25842.4 25017.04 0.968 50.0 49.0 NA NA NA NA 25017.04 25842.4 49.0 50.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.05714285714285732 1.6428571428571428 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 8 2 KHGGVSLSK KPGGVSLSK PickPocket 26985.39 50000.0 1.853 PickPocket 51.0 73.0 140 0.179 NA NA NA NA NA NA 26985.39 50000.0 1.853 51.0 73.0 NA NA NA NA 50000.0 26985.39 73.0 51.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.24285714285714294 0.3428571428571429 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 3 7 CQRAKVEMS CQRAKVAMS PickPocket 26985.39 26407.71 0.979 PickPocket 51.0 51.0 113 0.044 NA NA NA NA NA NA 26985.39 26407.71 0.979 51.0 51.0 NA NA NA NA 26407.71 26985.39 51.0 51.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.6857142857142857 -0.6857142857142857 True False False 1 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 7 5, 9 LPLLPLLLL LPLLLLLLG PickPocket 27278.95 50000.0 1.833 PickPocket 52.0 73.0 101 0.891 NA NA NA NA NA NA 27278.95 50000.0 1.833 52.0 73.0 NA NA NA NA 50000.0 27278.95 73.0 52.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 3.028571428571429 3.028571428571429 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 1 9 HHEDLIGKH HHEDLIGKP PickPocket 27278.95 27575.71 1.011 PickPocket 52.0 52.0 140 0.179 NA NA NA NA NA NA 27278.95 27575.71 1.011 52.0 52.0 NA NA NA NA 27575.71 27278.95 52.0 52.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.8857142857142858 -0.7857142857142859 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 10 NA STGQGSGEK NA PickPocket 27875.69 NA NA PickPocket 53.0 NA 142 0.768 NA NA NA NA NA NA 27875.69 NA NA 53.0 NA NA NA NA NA NA 27875.69 NA 53.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.842857142857143 -1.0000000000000002 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 6 4 ASGYESRVE ASGSESRVE PickPocket 27875.69 30726.73 1.102 PickPocket 53.0 56.0 116 0.043 NA NA NA NA NA NA 27875.69 30726.73 1.102 53.0 56.0 NA NA NA NA 30726.73 27875.69 56.0 53.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.4000000000000001 -1.0142857142857145 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 4 7 LSRTLLLAA LSRTLLAAA PickPocket 28178.94 27875.69 0.989 PickPocket 53.0 53.0 76 0.158 NA NA NA NA NA NA 28178.94 27875.69 0.989 53.0 53.0 NA NA NA NA 27875.69 28178.94 53.0 53.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.4 1.4 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 6 4 AGNLFNCEC AGNPFNCEC PickPocket 28178.94 20589.91 0.731 PickPocket 53.0 42.0 303 0.135 NA NA NA NA NA NA 28178.94 20589.91 0.731 53.0 42.0 NA NA NA NA 20589.91 28178.94 42.0 53.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.5 False True False 2 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 8 2 TTQKRNSRR TAQKRNSRR PickPocket 28795.36 50000.0 1.736 PickPocket 54.0 73.0 96 0.042 NA NA NA NA NA NA 28795.36 50000.0 1.736 54.0 73.0 NA NA NA NA 50000.0 28795.36 73.0 54.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.6 -2.5142857142857147 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 5 5 SPEPARPPQ SPEPPRPPQ PickPocket 29108.61 33869.37 1.164 PickPocket 54.0 60.0 245 0.486 NA NA NA NA NA NA 29108.61 33869.37 1.164 54.0 60.0 NA NA NA NA 33869.37 29108.61 60.0 54.0 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -1.6857142857142855 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 9 1 EMSHFEPNE AMSHFEPNE PickPocket 29108.61 13070.67 0.449 PickPocket 54.0 27.0 113 0.044 NA NA NA NA NA NA 29108.61 13070.67 0.449 54.0 27.0 NA NA NA NA 13070.67 29108.61 27.0 54.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.9000000000000001 -1.1285714285714286 True False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 3 7 VRPLELVYC VRPLELAYC PickPocket 30396.07 28178.94 0.927 PickPocket 56.0 53.0 113 0.053 NA NA NA NA NA NA 30396.07 28178.94 0.927 56.0 53.0 NA NA NA NA 28178.94 30396.07 53.0 56.0 6.USP18.ENST00000215794.7.missense.124A/V False 1.1285714285714286 1.1285714285714286 False True False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 7 3 NPQTDYLTG NPETDYLTG PickPocket 30726.73 50000.0 1.627 PickPocket 56.0 73.0 136 0.25 NA NA NA NA NA NA 30726.73 50000.0 1.627 56.0 73.0 NA NA NA NA 50000.0 30726.73 73.0 56.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.9000000000000001 -0.9000000000000001 False False False 0 True 1 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 4 6 DLIGKHGGV DLIGKPGGV PickPocket 31740.46 32434.8 1.022 PickPocket 57.0 58.0 140 0.179 NA NA NA NA NA NA 31740.46 32434.8 1.022 57.0 58.0 NA NA NA NA 32434.8 31740.46 58.0 57.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.05714285714285713 0.05714285714285713 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 3 7 TTVVVTTQK TTVVVTAQK PickPocket 31740.46 30396.07 0.958 PickPocket 57.0 56.0 96 0.042 NA NA NA NA NA NA 31740.46 30396.07 0.958 57.0 56.0 NA NA NA NA 30396.07 31740.46 56.0 57.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 0.5428571428571433 1.4000000000000001 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 5 5 GALVRSRTY GALVHSRTY PickPocket 32085.75 23444.56 0.731 PickPocket 58.0 46.0 210 0.686 NA NA NA NA NA NA 32085.75 23444.56 0.731 58.0 46.0 NA NA NA NA 23444.56 32085.75 46.0 58.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.5428571428571428 -0.05714285714285732 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 3 7 VQGIANQDA VQGIANEDA PickPocket 32434.8 34610.27 1.067 PickPocket 58.0 61.0 22 0.5 NA NA NA NA NA NA 32434.8 34610.27 1.067 58.0 61.0 NA NA NA NA 34610.27 32434.8 61.0 58.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 -0.0571428571428572 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 9 NA GSTGQGSGE NA PickPocket 32434.8 NA NA PickPocket 58.0 NA 142 0.768 NA NA NA NA NA NA 32434.8 NA NA 58.0 NA NA NA NA NA NA 32434.8 NA 58.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.3857142857142857 -1.0000000000000002 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 7 3 CTGSSGSIA CTRSSGSIA PickPocket 33144.32 21500.59 0.649 PickPocket 59.0 43.0 5 1.0 NA NA NA NA NA NA 33144.32 21500.59 0.649 59.0 43.0 NA NA NA NA 21500.59 33144.32 43.0 59.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.4428571428571428 0.4428571428571428 True False False 1 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 8 2 NNLLTEEED NHLLTEEED PickPocket 34237.82 35367.39 1.033 PickPocket 60.0 62.0 30 0.1 NA NA NA NA NA NA 34237.82 35367.39 1.033 60.0 62.0 NA NA NA NA 35367.39 34237.82 62.0 60.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 -1.0142857142857145 False False False 0 True 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 5 5 LIGKHGGVS LIGKPGGVS PickPocket 34237.82 45854.11 1.339 PickPocket 60.0 70.0 140 0.179 NA NA NA NA NA NA 34237.82 45854.11 1.339 60.0 70.0 NA NA NA NA 45854.11 34237.82 70.0 60.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.7000000000000001 0.05714285714285713 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 6 4 FLAFTRLTS FLASTRLTS PickPocket 34610.27 40270.83 1.164 PickPocket 61.0 66.0 171 0.959 NA NA NA NA NA NA 34610.27 40270.83 1.164 61.0 66.0 NA NA NA NA 40270.83 34610.27 66.0 61.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.24285714285714272 1.4000000000000001 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 7 3 LAFTRLTSE LASTRLTSE PickPocket 34610.27 50000.0 1.445 PickPocket 61.0 73.0 171 0.959 NA NA NA NA NA NA 34610.27 50000.0 1.445 61.0 73.0 NA NA NA NA 50000.0 34610.27 73.0 61.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.5142857142857143 0.8999999999999997 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 2 8 TVTISCTGS TVTISCTRS PickPocket 35752.13 50000.0 1.399 PickPocket 62.0 73.0 5 1.0 NA NA NA NA NA NA 35752.13 50000.0 1.399 62.0 73.0 NA NA NA NA 50000.0 35752.13 73.0 62.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.5142857142857142 1.2285714285714284 False False False 1 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 4 6 SHVWTHSRD SHVWTRSRD PickPocket 36931.66 43911.91 1.189 PickPocket 63.0 69.0 56 0.071 NA NA NA NA NA NA 36931.66 43911.91 1.189 63.0 69.0 NA NA NA NA 43911.91 36931.66 69.0 63.0 5.CECR2.ENST00000262608.8.missense.535R/H False -1.3428571428571427 -0.7714285714285714 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 10 1, 2 LPLLLLLGA PLLLLLLGA PickPocket 37333.42 30396.07 0.814 PickPocket 64.0 56.0 101 0.891 NA NA NA NA NA NA 37333.42 30396.07 0.814 64.0 56.0 NA NA NA NA 30396.07 37333.42 56.0 64.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.9142857142857146 3.028571428571429 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 3 8 TLSRTLLLA TLSRTLLAA PickPocket 37739.56 48929.64 1.297 PickPocket 64.0 73.0 76 0.158 NA NA NA NA NA NA 37739.56 48929.64 1.297 64.0 73.0 NA NA NA NA 48929.64 37739.56 73.0 64.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.0285714285714285 1.3142857142857143 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 1 9 LHTVSPEPA LHTVSPEPP PickPocket 37739.56 50000.0 1.325 PickPocket 64.0 73.0 245 0.486 NA NA NA NA NA NA 37739.56 50000.0 1.325 64.0 73.0 NA NA NA NA 50000.0 37739.56 73.0 64.0 15.GGA1.ENST00000343632.4.missense.484P/A False -0.31428571428571433 -0.2571428571428572 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 4 7, 8, 9 GGRSAGSTG GGRSAGQHW PickPocket 38150.11 49461.93 1.297 PickPocket 64.0 73.0 142 0.768 NA NA NA NA NA NA 38150.11 49461.93 1.297 64.0 73.0 NA NA NA NA 49461.93 38150.11 73.0 64.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8285714285714286 -0.7857142857142857 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 5 5 DDMDYLSDR DDMDCLSDR PickPocket 38565.12 50000.0 1.297 PickPocket 65.0 73.0 92 0.043 NA NA NA NA NA NA 38565.12 50000.0 1.297 65.0 73.0 NA NA NA NA 50000.0 38565.12 73.0 65.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.1285714285714286 -0.9857142857142857 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 5 5 PLELVYCLQ PLELAYCLQ PickPocket 39408.75 45360.65 1.151 PickPocket 65.0 70.0 113 0.053 NA NA NA NA NA NA 39408.75 45360.65 1.151 65.0 70.0 NA NA NA NA 45360.65 39408.75 70.0 65.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.8571428571428571 1.9000000000000001 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 4 6 TISCTGSSG TISCTRSSG PickPocket 39837.46 43911.91 1.102 PickPocket 66.0 69.0 5 1.0 NA NA NA NA NA NA 39837.46 43911.91 1.102 66.0 69.0 NA NA NA NA 43911.91 39837.46 69.0 66.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.19999999999999998 0.5142857142857142 False False False 1 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 2 8 HEDLIGKHG HEDLIGKPG PickPocket 39837.46 30396.07 0.763 PickPocket 66.0 56.0 140 0.179 NA NA NA NA NA NA 39837.46 30396.07 0.763 66.0 56.0 NA NA NA NA 30396.07 39837.46 56.0 66.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.44285714285714295 -0.44285714285714295 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 6 4 VVTTQKRNS VVTAQKRNS PickPocket 40708.92 36141.06 0.888 PickPocket 66.0 62.0 96 0.042 NA NA NA NA NA NA 40708.92 36141.06 0.888 66.0 62.0 NA NA NA NA 36141.06 40708.92 62.0 66.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -2.5142857142857147 -0.7000000000000001 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 5 5 VVVTTQKRN VVVTAQKRN PickPocket 41151.77 42971.89 1.044 PickPocket 67.0 68.0 96 0.042 NA NA NA NA NA NA 41151.77 42971.89 1.044 67.0 68.0 NA NA NA NA 42971.89 41151.77 68.0 67.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -1.8 0.5428571428571433 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 5 5 EALNNLLTE EALNHLLTE PickPocket 41599.44 40708.92 0.979 PickPocket 67.0 66.0 30 0.1 NA NA NA NA NA NA 41599.44 40708.92 0.979 67.0 66.0 NA NA NA NA 40708.92 41599.44 66.0 67.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.02857142857142847 0.7857142857142856 True False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 9 1 HGGVSLSKI PGGVSLSKI PickPocket 41599.44 50000.0 1.202 PickPocket 67.0 73.0 140 0.179 NA NA NA NA NA NA 41599.44 50000.0 1.202 67.0 73.0 NA NA NA NA 50000.0 41599.44 73.0 67.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.9428571428571428 0.9428571428571428 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 5 5 LAGNLFNCE LAGNPFNCE PickPocket 41599.44 50000.0 1.202 PickPocket 67.0 73.0 303 0.135 NA NA NA NA NA NA 41599.44 50000.0 1.202 67.0 73.0 NA NA NA NA 50000.0 41599.44 73.0 67.0 13.ELFN2.ENST00000402918.2.missense.186P/L False -0.2571428571428572 0.6857142857142856 False False False 1 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 2 8 HTVSPEPAR HTVSPEPPR PickPocket 41599.44 28178.94 0.677 PickPocket 67.0 53.0 245 0.486 NA NA NA NA NA NA 41599.44 28178.94 0.677 67.0 53.0 NA NA NA NA 28178.94 41599.44 53.0 67.0 15.GGA1.ENST00000343632.4.missense.484P/A False -0.8571428571428571 -0.31428571428571433 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 6 4 LELVYCLQK LELAYCLQK PickPocket 42051.98 35752.13 0.85 PickPocket 67.0 62.0 113 0.053 NA NA NA NA NA NA 42051.98 35752.13 0.85 67.0 62.0 NA NA NA NA 35752.13 42051.98 62.0 67.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.7999999999999999 1.9000000000000001 False False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 21 NA CPWSGTGQH NA PickPocket 42509.45 NA NA PickPocket 68.0 NA 142 0.768 NA NA NA NA NA NA 42509.45 NA NA 68.0 NA NA NA NA NA NA 42509.45 NA 68.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.4142857142857141 -0.3285714285714286 True False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 4 6 CDDMDYLSD CDDMDCLSD PickPocket 44389.61 50000.0 1.126 PickPocket 69.0 73.0 92 0.043 NA NA NA NA NA NA 44389.61 50000.0 1.126 69.0 73.0 NA NA NA NA 50000.0 44389.61 73.0 69.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.9857142857142857 -0.5142857142857142 True False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 7 NA SAGSTGQGS NA PickPocket 45360.65 NA NA PickPocket 70.0 NA 142 0.768 NA NA NA NA NA NA 45360.65 NA NA 70.0 NA NA NA NA NA NA 45360.65 NA 70.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 1 9 SGGSHVWTH SGGSHVWTR PickPocket 46352.93 50000.0 1.079 PickPocket 71.0 73.0 56 0.071 NA NA NA NA NA NA 46352.93 50000.0 1.079 71.0 73.0 NA NA NA NA 50000.0 46352.93 73.0 71.0 5.CECR2.ENST00000262608.8.missense.535R/H False -0.7142857142857143 -0.31428571428571433 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 7 3 GSAPTTVIY GSSPTTVIY PickPocket 46352.93 40270.83 0.869 PickPocket 71.0 66.0 7 0.571 NA NA NA NA NA NA 46352.93 40270.83 0.869 71.0 66.0 NA NA NA NA 40270.83 46352.93 66.0 71.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.8857142857142858 0.9571428571428572 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 1 9 AGTLKFNPQ AGTLKFNPE PickPocket 46857.18 43439.36 0.927 PickPocket 71.0 69.0 136 0.25 NA NA NA NA NA NA 46857.18 43439.36 0.927 71.0 69.0 NA NA NA NA 43439.36 46857.18 69.0 71.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.942857142857143 -0.0142857142857143 False False False 0 False 1 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 8 2 PQTDYLTGT PETDYLTGT PickPocket 46857.18 50000.0 1.067 PickPocket 71.0 73.0 136 0.25 NA NA NA NA NA NA 46857.18 50000.0 1.067 71.0 73.0 NA NA NA NA 50000.0 46857.18 73.0 71.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.5 -0.5 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 14 NA GSGEKAGCP NA PickPocket 47882.2 NA NA PickPocket 72.0 NA 142 0.768 NA NA NA NA NA NA 47882.2 NA NA 72.0 NA NA NA NA NA NA 47882.2 NA 72.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.7857142857142857 -0.6714285714285715 False False True 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 6 4 AKVEMSHFE AKVAMSHFE PickPocket 48403.09 44872.5 0.927 PickPocket 72.0 70.0 113 0.044 NA NA NA NA NA NA 48403.09 44872.5 0.927 72.0 70.0 NA NA NA NA 44872.5 48403.09 70.0 72.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.3000000000000001 -0.3000000000000001 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 3 9 PPPLLPLLP PPPLLPLLL PickPocket 50000.0 43911.91 0.878 PickPocket 73.0 69.0 101 0.891 NA NA NA NA NA NA 50000.0 43911.91 0.878 73.0 69.0 NA NA NA NA 43911.91 50000.0 69.0 73.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 1.4857142857142858 1.4857142857142858 False False True 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 4 8 PPLLPLLPL PPLLPLLLL PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 9 11 1 PLLLLLGAS LLLLLLGAS PickPocket 50000.0 21970.92 0.439 PickPocket 73.0 44.0 101 0.891 NA NA NA NA NA NA 50000.0 21970.92 0.439 73.0 44.0 NA NA NA NA 21970.92 50000.0 44.0 73.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.2571428571428567 2.9142857142857146 False False False 0 False 0 +4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 Not Run Not Run protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-G*01:09 9 2 9 SAAAAAAAV SAAAAAAAA PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 128 0.977 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A False 2.142857142857143 2.142857142857143 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 9 5 6, 9 SRTLLLAAA SRTLLAAAG PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 2.3000000000000003 2.3000000000000003 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 2 8 GGSHVWTHS GGSHVWTRS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 5.CECR2.ENST00000262608.8.missense.535R/H False -0.7714285714285714 -0.31428571428571433 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 8 2 THSRDPEGS TRSRDPEGS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 7 3 ELVYCLQKC ELAYCLQKC PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.6142857142857141 0.8571428571428571 True True False 2 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 4 6 NEALNNLLT NEALNHLLT PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.7857142857142856 0.7857142857142856 False False False 0 True 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 1 9 DAVQGIANQ DAVQGIANE PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.0571428571428572 0.7000000000000001 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 4 6 QGIANQDAA QGIANEDAA PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.08571428571428576 -0.08571428571428576 True False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 5 5 GIANQDAAQ GIANEDAAQ PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.2285714285714284 -0.08571428571428576 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 6 4 IANQDAAQG IANEDAAQG PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.5428571428571427 -0.08571428571428576 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 9 1 QDAAQGIAK EDAAQGIAK PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False 0.3 0.35714285714285715 True False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 8 2 TGSSGSIAS TRSSGSIAS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.38571428571428573 0.4428571428571428 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 9 1 GSSGSIASN RSSGSIASN PickPocket 50000.0 19505.61 0.39 PickPocket 73.0 40.0 5 1.0 NA NA NA NA NA NA 50000.0 19505.61 0.39 73.0 40.0 NA NA NA NA 19505.61 50000.0 40.0 73.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.0 0.4428571428571428 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 6 4 PGSAPTTVI PGSSPTTVI PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.9571428571428572 0.9571428571428572 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 9 1 APTTVIYED SPTTVIYED PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.14285714285714274 0.8857142857142858 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 9 3 7 EDLIGKHGG EDLIGKPGG PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 11.TPST2.ENST00000338754.4.missense.274P/H False -3.172065784643304e-17 -3.172065784643304e-17 True False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 1 9 SPVKEEEKT SPVKEEEKP PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.1142857142857143 -1.8 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 2 8 PVKEEEKTQ PVKEEEKPQ PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T False -3.2142857142857144 -2.1142857142857143 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 3 7 VKEEEKTQE VKEEEKPQE PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T False -3.1571428571428575 -2.1142857142857143 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 5 5 EEEKTQEVK EEEKPQEVK PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.1142857142857143 -2.0571428571428574 True False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 6 4 EEKTQEVKV EEKPQEVKV PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.014285714285714 -1.014285714285714 True False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 7 3 EKTQEVKVK EKPQEVKVK PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.0142857142857142 -1.014285714285714 True False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 4 6 ELAGNLFNC ELAGNPFNC PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.5 0.6857142857142856 True True False 1 False 0 +22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 Not Run Not Run protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-G*01:09 9 9 9 NMSSFKLKQ NMSSFKLKE PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 117 0.496 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 14.LGALS2.ENST00000215886.4.missense.132E/Q False -0.9000000000000001 -0.07142857142857155 False False False 0 True 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 3 7 TVSPEPARP TVSPEPPRP PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.6857142857142855 -0.31428571428571433 False False True 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 6 4 PEPARPPQQ PEPPRPPQQ PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -1.7999999999999996 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 7 3 EPARPPQQP EPPRPPQQP PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -2.0714285714285716 True False True 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 9 8 2 PARPPQQPV PPRPPQQPV PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.7285714285714289 -1.7285714285714289 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 2 9 GGGGRSAGS GGGGRSAGQ PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.7857142857142857 -0.7285714285714285 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 3 8, 9 GGGRSAGST GGGRSAGQH PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8285714285714286 -0.7285714285714286 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 5 6, 7, 8, 9 GRSAGSTGQ GRSAGQHWA PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6857142857142857 -0.6857142857142857 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 8 NA AGSTGQGSG NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 12 NA GQGSGEKAG NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0857142857142859 -1.0857142857142859 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 13 NA QGSGEKAGC NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6714285714285715 -0.6714285714285715 True True False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 16 NA GEKAGCPWS NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 17 NA EKAGCPWSG NA PickPocket 50000.0 NA NA PickPocket 73.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 73.0 NA NA NA NA NA NA 50000.0 NA 73.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False 0.02857142857142855 0.02857142857142855 True False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 9 3 7 PCDDMDYLS PCDDMDCLS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.9857142857142858 -0.5142857142857142 False False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 4 6 QRAKVEMSH QRAKVAMSH PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 113 0.044 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.5 -0.5 True False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 4 6 LKFNPQTDY LKFNPETDY PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.6142857142857143 -0.942857142857143 False False False 0 False 1 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 1 9 AKTTVVVTT AKTTVVVTA PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.4000000000000001 1.4000000000000001 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 4 6 TVVVTTQKR TVVVTAQKR PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -0.7000000000000001 1.0000000000000002 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 7 3 VTTQKRNSR VTAQKRNSR PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.0571428571428574 -1.8 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 9 1 TQKRNSRRQ AQKRNSRRQ PickPocket 50000.0 48403.09 0.968 PickPocket 73.0 72.0 96 0.042 NA NA NA NA NA NA 50000.0 48403.09 0.968 73.0 72.0 NA NA NA NA 48403.09 50000.0 72.0 73.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.6000000000000005 -3.0571428571428574 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 4 6 FGALVRSRT FGALVHSRT PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.09999999999999987 0.9857142857142857 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 8 2 VRSRTYDMD VHSRTYDMD PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.7714285714285716 -1.5857142857142856 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 1 9 EERTEASGY EERTEASGS PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.342857142857143 -1.342857142857143 True False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 2 8 ERTEASGYE ERTEASGSE PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.2 -1.2 True False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 4 6 TEASGYESR TEASGSESR PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.3571428571428572 -1.2 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 5 5 EASGYESRV EASGSESRV PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.0142857142857145 -1.0142857142857145 True False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 9 1 YESRVEPPH SESRVEPPH PickPocket 50000.0 50000.0 1.0 PickPocket 73.0 73.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 73.0 73.0 NA NA NA NA 50000.0 50000.0 73.0 73.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.5714285714285714 -1.5714285714285712 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 1 10 LYYSYGLLHI LYYSYGLLHT PickPocket 1469.28 2365.16 1.61 PickPocket 0.3 0.4 120 0.233 NA NA NA NA NA NA 1469.28 2365.16 1.61 0.3 0.4 NA NA NA NA 2365.16 1469.28 0.4 0.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9142857142857143 0.9142857142857143 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 1 10 MYQPCDDMDY MYQPCDDMDC PickPocket 2904.96 2873.7 0.989 PickPocket 0.5 0.5 92 0.043 NA NA NA NA NA NA 2904.96 2873.7 0.989 0.5 0.5 NA NA NA NA 2873.7 2904.96 0.5 0.5 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 9 2 HIYGSGGYAL HTYGSGGYAL PickPocket 3766.31 3567.97 0.947 PickPocket 0.8 0.7 120 0.233 NA NA NA NA NA NA 3766.31 3567.97 0.947 0.8 0.7 NA NA NA NA 3567.97 3766.31 0.7 0.8 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.32857142857142857 0.32857142857142857 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 1 10 QWYQQRPGSA QWYQQRPGSS PickPocket 5267.25 6755.55 1.283 PickPocket 1.6 2.5 7 0.571 NA NA NA NA NA NA 5267.25 6755.55 1.283 1.6 2.5 NA NA NA NA 6755.55 5267.25 2.5 1.6 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.7857142857142858 -1.7857142857142858 True False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 9 2 LVYCLQKCNV LAYCLQKCNV PickPocket 5997.52 12382.34 2.065 PickPocket 2.1 7.4 113 0.053 NA NA NA NA NA NA 5997.52 12382.34 2.065 2.1 7.4 NA NA NA NA 12382.34 5997.52 7.4 2.1 6.USP18.ENST00000215794.7.missense.124A/V False 0.3 0.7999999999999999 False False False 2 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 3 8 YSYGLLHIYG YSYGLLHTYG PickPocket 6399.79 6195.39 0.968 PickPocket 2.3 2.2 120 0.233 NA NA NA NA NA NA 6399.79 6195.39 0.968 2.3 2.2 NA NA NA NA 6195.39 6399.79 2.2 2.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9714285714285714 0.9714285714285714 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 2 9 YQPCDDMDYL YQPCDDMDCL PickPocket 6610.93 7860.43 1.189 PickPocket 2.4 3.5 92 0.043 NA NA NA NA NA NA 6610.93 7860.43 1.189 2.4 3.5 NA NA NA NA 7860.43 6610.93 3.5 2.4 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.5142857142857142 -0.5142857142857142 False False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 4 7 GWEFLAFTRL GWEFLASTRL PickPocket 7054.34 6978.43 0.989 PickPocket 2.8 2.7 171 0.959 NA NA NA NA NA NA 7054.34 6978.43 0.989 2.8 2.7 NA NA NA NA 6978.43 7054.34 2.7 2.8 22.PANX2.ENST00000395842.2.missense.147S/F False 1.4000000000000001 1.4000000000000001 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 1 10 LLHTVSPEPA LLHTVSPEPP PickPocket 9654.43 13797.25 1.429 PickPocket 5.0 8.8 245 0.486 NA NA NA NA NA NA 9654.43 13797.25 1.429 5.0 8.8 NA NA NA NA 13797.25 9654.43 8.8 5.0 15.GGA1.ENST00000343632.4.missense.484P/A False -0.31428571428571433 0.7857142857142857 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 7 4 LLHIYGSGGY LLHTYGSGGY PickPocket 9972.95 8853.9 0.888 PickPocket 5.3 4.4 120 0.233 NA NA NA NA NA NA 9972.95 8853.9 0.888 5.3 4.4 NA NA NA NA 8853.9 9972.95 4.4 5.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.014285714285714266 0.914285714285714 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 3 8 AVQGIANQDA AVQGIANEDA PickPocket 11355.63 11355.63 1.0 PickPocket 6.4 6.4 22 0.5 NA NA NA NA NA NA 11355.63 11355.63 1.0 6.4 6.4 NA NA NA NA 11355.63 11355.63 6.4 6.4 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 0.7000000000000001 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 9 2 KTQEVKVKEP KPQEVKVKEP PickPocket 11604.04 40708.92 3.508 PickPocket 6.6 35.0 185 0.038 NA NA NA NA NA NA 11604.04 40708.92 3.508 6.6 35.0 NA NA NA NA 40708.92 11604.04 35.0 6.6 12.NEFH.ENST00000310624.6.missense.830P/T False -1.1428571428571428 -1.014285714285714 False False True 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 9 2 GYESRVEPPH GSESRVEPPH PickPocket 11604.04 45854.11 3.952 PickPocket 6.6 40.0 116 0.043 NA NA NA NA NA NA 11604.04 45854.11 3.952 6.6 40.0 NA NA NA NA 45854.11 11604.04 40.0 6.6 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.5714285714285714 -1.4000000000000001 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 2 9 KSVNEALNNL KSVNEALNHL PickPocket 11730.27 16946.23 1.445 PickPocket 6.7 13.0 30 0.1 NA NA NA NA NA NA 11730.27 16946.23 1.445 6.7 13.0 NA NA NA NA 16946.23 11730.27 13.0 6.7 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 9 2 DYLSDRCKIL DCLSDRCKIL PickPocket 11986.87 50000.0 4.171 PickPocket 6.9 43.0 92 0.043 NA NA NA NA NA NA 11986.87 50000.0 4.171 6.9 43.0 NA NA NA NA 50000.0 11986.87 43.0 6.9 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.27142857142857163 -0.27142857142857146 False False False 1 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 7 6, 10 LLPLLPLLLL LLPLLLLLLG PickPocket 12249.09 29745.37 2.428 PickPocket 7.2 26.0 101 0.891 NA NA NA NA NA NA 12249.09 29745.37 2.428 7.2 26.0 NA NA NA NA 29745.37 12249.09 26.0 7.2 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 3.028571428571429 3.028571428571429 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 1 10 LMVCELAGNL LMVCELAGNP PickPocket 12249.09 36141.06 2.951 PickPocket 7.2 32.0 303 0.135 NA NA NA NA NA NA 12249.09 36141.06 2.951 7.2 32.0 NA NA NA NA 36141.06 12249.09 32.0 7.2 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6428571428571427 2.0714285714285716 False False False 1 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 2 9 WYQQRPGSAP WYQQRPGSSP PickPocket 12382.34 9550.53 0.771 PickPocket 7.4 4.9 7 0.571 NA NA NA NA NA NA 12382.34 9550.53 0.771 7.4 4.9 NA NA NA NA 9550.53 12382.34 4.9 7.4 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.5142857142857142 -1.5142857142857142 False False True 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 6 5 KFNPQTDYLT KFNPETDYLT PickPocket 13070.67 13212.86 1.011 PickPocket 8.1 8.2 136 0.25 NA NA NA NA NA NA 13070.67 13212.86 1.011 8.1 8.2 NA NA NA NA 13212.86 13070.67 8.2 8.1 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.0714285714285716 -1.0714285714285716 False False False 0 False 1 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 8 3 WTHSRDPEGS WTRSRDPEGS PickPocket 14099.07 50000.0 3.546 PickPocket 9.1 43.0 56 0.071 NA NA NA NA NA NA 14099.07 50000.0 3.546 9.1 43.0 NA NA NA NA 50000.0 14099.07 43.0 9.1 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 3 8 SVNEALNNLL SVNEALNHLL PickPocket 14099.07 15541.08 1.102 PickPocket 9.1 12.0 30 0.1 NA NA NA NA NA NA 14099.07 15541.08 1.102 9.1 12.0 NA NA NA NA 15541.08 14099.07 12.0 9.1 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.3857142857142856 0.3857142857142856 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 7 1, 2, 3 RTLLLAAAGG SRTLLAAAGG PickPocket 14564.23 50000.0 3.433 PickPocket 9.4 43.0 76 0.158 NA NA NA NA NA NA 14564.23 50000.0 3.433 9.4 43.0 NA NA NA NA 50000.0 14564.23 43.0 9.4 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.742857142857143 2.342857142857143 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 8 3 GNLFNCECDL GNPFNCECDL PickPocket 14564.23 11112.54 0.763 PickPocket 9.4 6.3 303 0.135 NA NA NA NA NA NA 14564.23 11112.54 0.763 9.4 6.3 NA NA NA NA 11112.54 14564.23 6.3 9.4 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 2 9 MVCELAGNLF MVCELAGNPF PickPocket 15044.73 13501.89 0.897 PickPocket 9.9 8.5 303 0.135 NA NA NA NA NA NA 15044.73 13501.89 0.897 9.9 8.5 NA NA NA NA 13501.89 15044.73 8.5 9.9 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6857142857142856 1.4714285714285713 False False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 8 3 KVEMSHFEPN KVAMSHFEPN PickPocket 15208.39 47366.92 3.115 PickPocket 11.0 41.0 113 0.044 NA NA NA NA NA NA 15208.39 47366.92 3.115 11.0 41.0 NA NA NA NA 47366.92 15208.39 41.0 11.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.1285714285714286 -0.3000000000000001 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 4 7 GSHVWTHSRD GSHVWTRSRD PickPocket 16053.81 17695.75 1.102 PickPocket 12.0 14.0 56 0.071 NA NA NA NA NA NA 16053.81 17695.75 1.102 12.0 14.0 NA NA NA NA 17695.75 16053.81 14.0 12.0 5.CECR2.ENST00000262608.8.missense.535R/H False -1.3428571428571427 -0.7142857142857143 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 8 3 SGYESRVEPP SGSESRVEPP PickPocket 16583.46 50000.0 3.015 PickPocket 13.0 43.0 116 0.043 NA NA NA NA NA NA 16583.46 50000.0 3.015 13.0 43.0 NA NA NA NA 50000.0 16583.46 43.0 13.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.6142857142857143 -1.0142857142857145 False False True 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 6 5 HVWTHSRDPE HVWTRSRDPE PickPocket 18882.64 23699.6 1.255 PickPocket 15.0 19.0 56 0.071 NA NA NA NA NA NA 18882.64 23699.6 1.255 15.0 19.0 NA NA NA NA 23699.6 18882.64 19.0 15.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5428571428571423 -1.3000000000000003 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 8 3 MDYLSDRCKI MDCLSDRCKI PickPocket 18882.64 50000.0 2.648 PickPocket 15.0 43.0 92 0.043 NA NA NA NA NA NA 18882.64 50000.0 2.648 15.0 43.0 NA NA NA NA 50000.0 18882.64 43.0 15.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.27142857142857146 -0.27142857142857146 False False False 1 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 3 8 YQQRPGSAPT YQQRPGSSPT PickPocket 19088.05 18279.56 0.958 PickPocket 15.0 14.0 7 0.571 NA NA NA NA NA NA 19088.05 18279.56 0.958 15.0 14.0 NA NA NA NA 18279.56 19088.05 14.0 15.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.1142857142857143 -1.1142857142857143 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 10 1 IYGSGGYALY TYGSGGYALY PickPocket 19295.7 22451.54 1.164 PickPocket 15.0 18.0 120 0.233 NA NA NA NA NA NA 19295.7 22451.54 1.164 15.0 18.0 NA NA NA NA 22451.54 19295.7 18.0 15.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.1999999999999999 0.32857142857142857 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 2 9 YYSYGLLHIY YYSYGLLHTY PickPocket 20149.14 15881.05 0.788 PickPocket 16.0 12.0 120 0.233 NA NA NA NA NA NA 20149.14 15881.05 0.788 16.0 12.0 NA NA NA NA 15881.05 20149.14 12.0 16.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.8428571428571427 0.9142857142857143 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 4 7 SYGLLHIYGS SYGLLHTYGS PickPocket 20149.14 17505.31 0.869 PickPocket 16.0 13.0 120 0.233 NA NA NA NA NA NA 20149.14 17505.31 0.869 16.0 13.0 NA NA NA NA 17505.31 20149.14 13.0 16.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.914285714285714 0.9714285714285714 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 4 7 RTEASGYESR RTEASGSESR PickPocket 20368.33 20813.9 1.022 PickPocket 16.0 17.0 116 0.043 NA NA NA NA NA NA 20368.33 20813.9 1.022 16.0 17.0 NA NA NA NA 20813.9 20368.33 17.0 16.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.3571428571428572 -1.2 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 10 2, 3 LLPLLLLLGA LPLLLLLLGA PickPocket 20589.91 50000.0 2.428 PickPocket 16.0 43.0 101 0.891 NA NA NA NA NA NA 20589.91 50000.0 2.428 16.0 43.0 NA NA NA NA 50000.0 20589.91 43.0 16.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.9142857142857146 3.028571428571429 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 10 1 VYCLQKCNVP AYCLQKCNVP PickPocket 22209.93 18082.85 0.814 PickPocket 18.0 14.0 113 0.053 NA NA NA NA NA NA 22209.93 18082.85 0.814 18.0 14.0 NA NA NA NA 18082.85 22209.93 14.0 18.0 6.USP18.ENST00000215794.7.missense.124A/V False -0.28571428571428564 0.6142857142857141 False False True 2 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 3 9 ATLSRTLLLA ATLSRTLLAA PickPocket 22942.68 28485.48 1.242 PickPocket 19.0 24.0 76 0.158 NA NA NA NA NA NA 22942.68 28485.48 1.242 19.0 24.0 NA NA NA NA 28485.48 22942.68 24.0 19.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.0285714285714285 1.3142857142857143 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 10 1 LFNCECDLFG PFNCECDLFG PickPocket 23192.26 50000.0 2.156 PickPocket 19.0 43.0 303 0.135 NA NA NA NA NA NA 23192.26 50000.0 2.156 19.0 43.0 NA NA NA NA 50000.0 23192.26 43.0 19.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.5999999999999999 0.5999999999999999 False False False 2 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 9 2 NLFNCECDLF NPFNCECDLF PickPocket 23699.6 50000.0 2.11 PickPocket 19.0 43.0 303 0.135 NA NA NA NA NA NA 23699.6 50000.0 2.11 19.0 43.0 NA NA NA NA 50000.0 23699.6 43.0 19.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.15714285714285708 False False False 2 True 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 6 5 GLLHIYGSGG GLLHTYGSGG PickPocket 23699.6 25564.3 1.079 PickPocket 19.0 21.0 120 0.233 NA NA NA NA NA NA 23699.6 25564.3 1.079 19.0 21.0 NA NA NA NA 25564.3 23699.6 21.0 19.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.2857142857142857 0.9714285714285714 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 10 1 FTRLTSELNF STRLTSELNF PickPocket 24218.04 19932.31 0.823 PickPocket 20.0 16.0 171 0.959 NA NA NA NA NA NA 24218.04 19932.31 0.823 20.0 16.0 NA NA NA NA 19932.31 24218.04 16.0 20.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.27142857142857135 0.27142857142857135 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 1 10 SVLCQRAKVE SVLCQRAKVA PickPocket 24747.82 21269.21 0.859 PickPocket 20.0 17.0 113 0.044 NA NA NA NA NA NA 24747.82 21269.21 0.859 20.0 17.0 NA NA NA NA 21269.21 24747.82 17.0 20.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.9857142857142857 0.4999999999999999 False False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 8 3 LAFTRLTSEL LASTRLTSEL PickPocket 24747.82 50000.0 2.02 PickPocket 20.0 43.0 171 0.959 NA NA NA NA NA NA 24747.82 50000.0 2.02 20.0 43.0 NA NA NA NA 50000.0 24747.82 43.0 20.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.3714285714285715 0.8999999999999997 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 8 3 ANQDAAQGIA ANEDAAQGIA PickPocket 25017.04 42509.45 1.699 PickPocket 21.0 37.0 22 0.5 NA NA NA NA NA NA 25017.04 42509.45 1.699 21.0 37.0 NA NA NA NA 42509.45 25017.04 37.0 21.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False 0.35714285714285715 0.35714285714285715 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 6 5 EFLAFTRLTS EFLASTRLTS PickPocket 25289.19 30396.07 1.202 PickPocket 21.0 26.0 171 0.959 NA NA NA NA NA NA 25289.19 30396.07 1.202 21.0 26.0 NA NA NA NA 30396.07 25289.19 26.0 21.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.24285714285714272 1.4000000000000001 True False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 2 9 KTVTISCTGS KTVTISCTRS PickPocket 25564.3 37739.56 1.476 PickPocket 21.0 33.0 5 1.0 NA NA NA NA NA NA 25564.3 37739.56 1.476 21.0 33.0 NA NA NA NA 37739.56 25564.3 33.0 21.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.5142857142857142 1.2285714285714284 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 6 5 ISCTGSSGSI ISCTRSSGSI PickPocket 26407.71 31740.46 1.202 PickPocket 22.0 28.0 5 1.0 NA NA NA NA NA NA 26407.71 31740.46 1.202 22.0 28.0 NA NA NA NA 31740.46 26407.71 28.0 22.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.08571428571428566 0.5 False False False 1 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 1 10 KSPVKEEEKT KSPVKEEEKP PickPocket 26985.39 34237.82 1.269 PickPocket 23.0 30.0 185 0.038 NA NA NA NA NA NA 26985.39 34237.82 1.269 23.0 30.0 NA NA NA NA 34237.82 26985.39 30.0 23.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.1142857142857143 -1.8 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 9 2 VEMSHFEPNE VAMSHFEPNE PickPocket 27278.95 20589.91 0.755 PickPocket 23.0 16.0 113 0.044 NA NA NA NA NA NA 27278.95 20589.91 0.755 23.0 16.0 NA NA NA NA 20589.91 27278.95 16.0 23.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.9000000000000001 -0.3000000000000001 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 7 4 ALVRSRTYDM ALVHSRTYDM PickPocket 27875.69 26123.53 0.937 PickPocket 24.0 22.0 210 0.686 NA NA NA NA NA NA 27875.69 26123.53 0.937 24.0 22.0 NA NA NA NA 26123.53 27875.69 22.0 24.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.9142857142857144 -0.09999999999999987 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 3 8 GTLKFNPQTD GTLKFNPETD PickPocket 28178.94 28178.94 1.0 PickPocket 24.0 24.0 136 0.25 NA NA NA NA NA NA 28178.94 28178.94 1.0 24.0 24.0 NA NA NA NA 28178.94 28178.94 24.0 24.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.9857142857142855 -0.5000000000000001 False False False 0 False 1 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 9 2 AFTRLTSELN ASTRLTSELN PickPocket 28485.48 50000.0 1.755 PickPocket 24.0 43.0 171 0.959 NA NA NA NA NA NA 28485.48 50000.0 1.755 24.0 43.0 NA NA NA NA 50000.0 28485.48 43.0 24.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.7714285714285715 0.24285714285714272 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 6 7 PLLPLLPLLL PLLPLLLLLL PickPocket 29425.27 31398.89 1.067 PickPocket 25.0 27.0 101 0.891 NA NA NA NA NA NA 29425.27 31398.89 1.067 25.0 27.0 NA NA NA NA 31398.89 29425.27 27.0 25.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 10 1 RSRTYDMDVR HSRTYDMDVR PickPocket 29745.37 49461.93 1.663 PickPocket 26.0 42.0 210 0.686 NA NA NA NA NA NA 29745.37 49461.93 1.663 26.0 42.0 NA NA NA NA 49461.93 29745.37 42.0 26.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 2 9 VLCQRAKVEM VLCQRAKVAM PickPocket 30068.96 43911.91 1.46 PickPocket 26.0 38.0 113 0.044 NA NA NA NA NA NA 30068.96 43911.91 1.46 26.0 38.0 NA NA NA NA 43911.91 30068.96 38.0 26.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.0714285714285712 0.0571428571428572 False False False 1 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 3 8 AVRPLELVYC AVRPLELAYC PickPocket 30726.73 31740.46 1.033 PickPocket 26.0 28.0 113 0.053 NA NA NA NA NA NA 30726.73 31740.46 1.033 26.0 28.0 NA NA NA NA 31740.46 30726.73 28.0 26.0 6.USP18.ENST00000215794.7.missense.124A/V False 1.1285714285714286 1.1285714285714286 False True False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 10 1 QTDYLTGTDG ETDYLTGTDG PickPocket 31398.89 50000.0 1.592 PickPocket 27.0 43.0 136 0.25 NA NA NA NA NA NA 31398.89 50000.0 1.592 27.0 43.0 NA NA NA NA 50000.0 31398.89 43.0 27.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.45714285714285713 -0.45714285714285713 True False False 0 False 0 +22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 Not Run Not Run protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-G*01:09 10 10 10 FNMSSFKLKQ FNMSSFKLKE PickPocket 31740.46 29425.27 0.927 PickPocket 28.0 25.0 117 0.496 NA NA NA NA NA NA 31740.46 29425.27 0.927 28.0 25.0 NA NA NA NA 29425.27 31740.46 25.0 28.0 14.LGALS2.ENST00000215886.4.missense.132E/Q False -0.9000000000000001 -0.07142857142857155 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 5 6 VSPEPARPPQ VSPEPPRPPQ PickPocket 31740.46 32787.64 1.033 PickPocket 28.0 29.0 245 0.486 NA NA NA NA NA NA 31740.46 32787.64 1.033 28.0 29.0 NA NA NA NA 32787.64 31740.46 29.0 28.0 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -0.8571428571428571 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 7 4 VWTHSRDPEG VWTRSRDPEG PickPocket 32085.75 34237.82 1.067 PickPocket 28.0 30.0 56 0.071 NA NA NA NA NA NA 32085.75 34237.82 1.067 28.0 30.0 NA NA NA NA 34237.82 32085.75 30.0 28.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5 -1.3428571428571427 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 7 4 ALNNLLTEEE ALNHLLTEEE PickPocket 32085.75 33869.37 1.056 PickPocket 28.0 30.0 30 0.1 NA NA NA NA NA NA 32085.75 33869.37 1.056 28.0 30.0 NA NA NA NA 33869.37 32085.75 30.0 28.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.7857142857142856 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 9 1 LLLAAAGGSS TLLAAAGGSS PickPocket 32434.8 32787.64 1.011 PickPocket 28.0 29.0 76 0.158 NA NA NA NA NA NA 32434.8 32787.64 1.011 28.0 29.0 NA NA NA NA 32787.64 32434.8 29.0 28.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 0.42857142857142855 2.342857142857143 False False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 7 4 FNPQTDYLTG FNPETDYLTG PickPocket 33869.37 31060.99 0.917 PickPocket 30.0 27.0 136 0.25 NA NA NA NA NA NA 33869.37 31060.99 0.917 30.0 27.0 NA NA NA NA 31060.99 33869.37 27.0 30.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.9000000000000001 -0.9000000000000001 False False False 0 False 1 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 4 7 VRPLELVYCL VRPLELAYCL PickPocket 34986.78 35367.39 1.011 PickPocket 31.0 31.0 113 0.053 NA NA NA NA NA NA 34986.78 35367.39 1.011 31.0 31.0 NA NA NA NA 35367.39 34986.78 31.0 31.0 6.USP18.ENST00000215794.7.missense.124A/V False 1.9000000000000001 1.9000000000000001 False False False 1 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 5 6 LKFNPQTDYL LKFNPETDYL PickPocket 34986.78 36931.66 1.056 PickPocket 31.0 32.0 136 0.25 NA NA NA NA NA NA 34986.78 36931.66 1.056 31.0 32.0 NA NA NA NA 36931.66 34986.78 32.0 31.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.4714285714285715 -0.942857142857143 False False False 0 False 1 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 8 1, 2 TLLLAAAGGS RTLLAAAGGS PickPocket 36931.66 14099.07 0.382 PickPocket 32.0 9.1 76 0.158 NA NA NA NA NA NA 36931.66 14099.07 0.382 32.0 9.1 NA NA NA NA 14099.07 36931.66 9.1 32.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.0857142857142856 2.342857142857143 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 6 5 LIGKHGGVSL LIGKPGGVSL PickPocket 36931.66 43439.36 1.176 PickPocket 32.0 38.0 140 0.179 NA NA NA NA NA NA 36931.66 43439.36 1.176 32.0 38.0 NA NA NA NA 43439.36 36931.66 38.0 32.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.10000000000000002 0.05714285714285713 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 3 8 SLFGALVRSR SLFGALVHSR PickPocket 37333.42 35752.13 0.958 PickPocket 33.0 31.0 210 0.686 NA NA NA NA NA NA 37333.42 35752.13 0.958 33.0 31.0 NA NA NA NA 35752.13 37333.42 31.0 33.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.05714285714285732 2.1714285714285713 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 16 NA SGEKAGCPWS NA PickPocket 37739.56 NA NA PickPocket 33.0 NA 142 0.768 NA NA NA NA NA NA 37739.56 NA NA 33.0 NA NA NA NA NA NA 37739.56 NA 33.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 9 2 TTQKRNSRRQ TAQKRNSRRQ PickPocket 37739.56 50000.0 1.325 PickPocket 33.0 43.0 96 0.042 NA NA NA NA NA NA 37739.56 50000.0 1.325 33.0 43.0 NA NA NA NA 50000.0 37739.56 43.0 33.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.6000000000000005 -2.5142857142857147 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 1 10 LHHEDLIGKH LHHEDLIGKP PickPocket 38150.11 38565.12 1.011 PickPocket 33.0 34.0 140 0.179 NA NA NA NA NA NA 38150.11 38565.12 1.011 33.0 34.0 NA NA NA NA 38565.12 38150.11 34.0 33.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.8857142857142858 -0.18571428571428594 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 9 2 SAPTTVIYED SSPTTVIYED PickPocket 38565.12 21734.48 0.564 PickPocket 34.0 18.0 7 0.571 NA NA NA NA NA NA 38565.12 21734.48 0.564 34.0 18.0 NA NA NA NA 21734.48 38565.12 18.0 34.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.14285714285714274 0.9571428571428572 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 3 8 KTTVVVTTQK KTTVVVTAQK PickPocket 38984.65 40708.92 1.044 PickPocket 34.0 35.0 96 0.042 NA NA NA NA NA NA 38984.65 40708.92 1.044 34.0 35.0 NA NA NA NA 40708.92 38984.65 35.0 34.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 0.5428571428571433 1.4000000000000001 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 5 6 RPLELVYCLQ RPLELAYCLQ PickPocket 40708.92 44389.61 1.09 PickPocket 35.0 39.0 113 0.053 NA NA NA NA NA NA 40708.92 44389.61 1.09 35.0 39.0 NA NA NA NA 44389.61 40708.92 39.0 35.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.8571428571428571 1.9000000000000001 False False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 2 9 ALGWEFLAFT ALGWEFLAST PickPocket 41151.77 50000.0 1.215 PickPocket 36.0 43.0 171 0.959 NA NA NA NA NA NA 41151.77 50000.0 1.215 36.0 43.0 NA NA NA NA 50000.0 41151.77 43.0 36.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.8714285714285712 1.0571428571428572 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 1 10 RSGGSHVWTH RSGGSHVWTR PickPocket 41599.44 50000.0 1.202 PickPocket 36.0 43.0 56 0.071 NA NA NA NA NA NA 41599.44 50000.0 1.202 36.0 43.0 NA NA NA NA 50000.0 41599.44 43.0 36.0 5.CECR2.ENST00000262608.8.missense.535R/H False -0.7142857142857143 -0.31428571428571433 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 20 NA AGCPWSGTGQ NA PickPocket 41599.44 NA NA PickPocket 36.0 NA 142 0.768 NA NA NA NA NA NA 41599.44 NA NA 36.0 NA NA NA NA NA NA 41599.44 NA 36.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.1857142857142857 0.02857142857142855 False False False 1 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 1 10 REERTEASGY REERTEASGS PickPocket 41599.44 46857.18 1.126 PickPocket 36.0 41.0 116 0.043 NA NA NA NA NA NA 41599.44 46857.18 1.126 36.0 41.0 NA NA NA NA 46857.18 41599.44 41.0 36.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.342857142857143 -1.342857142857143 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 10 1 NLLTEEEDYQ HLLTEEEDYQ PickPocket 42509.45 21970.92 0.517 PickPocket 37.0 18.0 30 0.1 NA NA NA NA NA NA 42509.45 21970.92 0.517 37.0 18.0 NA NA NA NA 21970.92 42509.45 18.0 37.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -2.7857142857142856 -1.0142857142857145 False False False 0 True 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 9 2 KHGGVSLSKI KPGGVSLSKI PickPocket 42971.89 50000.0 1.164 PickPocket 37.0 43.0 140 0.179 NA NA NA NA NA NA 42971.89 50000.0 1.164 37.0 43.0 NA NA NA NA 50000.0 42971.89 43.0 37.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.9428571428571428 0.9428571428571428 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 4 7 QQRPGSAPTT QQRPGSSPTT PickPocket 43439.36 42051.98 0.968 PickPocket 38.0 37.0 7 0.571 NA NA NA NA NA NA 43439.36 42051.98 0.968 38.0 37.0 NA NA NA NA 42051.98 43439.36 37.0 38.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.5714285714285714 -0.5714285714285714 True False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 5 6 QRPGSAPTTV QRPGSSPTTV PickPocket 44389.61 43439.36 0.979 PickPocket 39.0 38.0 7 0.571 NA NA NA NA NA NA 44389.61 43439.36 0.979 39.0 38.0 NA NA NA NA 43439.36 44389.61 38.0 39.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.2571428571428571 0.2571428571428571 True False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 7 NA RSAGSTGQGS NA PickPocket 44389.61 NA NA PickPocket 39.0 NA 142 0.768 NA NA NA NA NA NA 44389.61 NA NA 39.0 NA NA NA NA NA NA 44389.61 NA 39.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 4 7 VNEALNNLLT VNEALNHLLT PickPocket 45360.65 45854.11 1.011 PickPocket 39.0 40.0 30 0.1 NA NA NA NA NA NA 45360.65 45854.11 1.011 39.0 40.0 NA NA NA NA 45854.11 45360.65 40.0 39.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.7857142857142856 0.7857142857142856 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 2 9 HHEDLIGKHG HHEDLIGKPG PickPocket 45360.65 36141.06 0.797 PickPocket 39.0 32.0 140 0.179 NA NA NA NA NA NA 45360.65 36141.06 0.797 39.0 32.0 NA NA NA NA 36141.06 45360.65 32.0 39.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.44285714285714295 -0.44285714285714295 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 8 3 LHIYGSGGYA LHTYGSGGYA PickPocket 45360.65 50000.0 1.102 PickPocket 39.0 43.0 120 0.233 NA NA NA NA NA NA 45360.65 50000.0 1.102 39.0 43.0 NA NA NA NA 50000.0 45360.65 43.0 39.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False -0.39999999999999997 0.3142857142857142 False False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 5 6 YGLLHIYGSG YGLLHTYGSG PickPocket 46352.93 42509.45 0.917 PickPocket 40.0 37.0 120 0.233 NA NA NA NA NA NA 46352.93 42509.45 0.917 40.0 37.0 NA NA NA NA 42509.45 46352.93 37.0 40.0 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.3142857142857142 0.9714285714285714 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 21 NA GCPWSGTGQH NA PickPocket 47882.2 NA NA PickPocket 41.0 NA 142 0.768 NA NA NA NA NA NA 47882.2 NA NA 41.0 NA NA NA NA NA NA 47882.2 NA 41.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.4142857142857141 -0.32857142857142857 False False False 1 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 6 5 RPGSAPTTVI RPGSSPTTVI PickPocket 48403.09 50000.0 1.033 PickPocket 42.0 43.0 7 0.571 NA NA NA NA NA NA 48403.09 50000.0 1.033 42.0 43.0 NA NA NA NA 50000.0 48403.09 43.0 42.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.9571428571428572 0.9571428571428572 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 10 1 TQKRNSRRQL AQKRNSRRQL PickPocket 48403.09 41599.44 0.859 PickPocket 42.0 36.0 96 0.042 NA NA NA NA NA NA 48403.09 41599.44 0.859 42.0 36.0 NA NA NA NA 41599.44 48403.09 36.0 42.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -2.5 -2.5 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 2 9 VSLFGALVRS VSLFGALVHS PickPocket 48929.64 42971.89 0.878 PickPocket 42.0 37.0 210 0.686 NA NA NA NA NA NA 48929.64 42971.89 0.878 42.0 37.0 NA NA NA NA 42971.89 48929.64 37.0 42.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False 0.9857142857142857 2.1714285714285713 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 4 7 VTISCTGSSG VTISCTRSSG PickPocket 49461.93 50000.0 1.011 PickPocket 42.0 43.0 5 1.0 NA NA NA NA NA NA 49461.93 50000.0 1.011 42.0 43.0 NA NA NA NA 50000.0 49461.93 43.0 42.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.19999999999999998 1.2285714285714284 False False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 3 8 LCQRAKVEMS LCQRAKVAMS PickPocket 49461.93 50000.0 1.011 PickPocket 42.0 43.0 113 0.044 NA NA NA NA NA NA 49461.93 50000.0 1.011 42.0 43.0 NA NA NA NA 50000.0 49461.93 43.0 42.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.6857142857142857 0.0571428571428572 False False False 1 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 3 10 PPPPLLPLLP PPPPLLPLLL PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 1.4857142857142858 1.4857142857142858 False False True 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 4 9 PPPLLPLLPL PPPLLPLLLL PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 5 8 PPLLPLLPLL PPLLPLLLLL PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 8 1, 2, 4, 5 LPLLPLLLLL PLLPLLLLLL PickPocket 50000.0 31398.89 0.628 PickPocket 43.0 27.0 101 0.891 NA NA NA NA NA NA 50000.0 31398.89 0.628 43.0 27.0 NA NA NA NA 31398.89 50000.0 27.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 3.028571428571429 3.028571428571429 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 9 1, 3, 4 PLLPLLLLLG LLPLLLLLLG PickPocket 50000.0 29745.37 0.595 PickPocket 43.0 26.0 101 0.891 NA NA NA NA NA NA 50000.0 29745.37 0.595 43.0 26.0 NA NA NA NA 29745.37 50000.0 26.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.4285714285714293 3.028571428571429 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 11 1, 2 LPLLLLLGAS PLLLLLLGAS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 101 0.891 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.2571428571428567 3.028571428571429 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-G*01:09 10 12 1 PLLLLLGASG LLLLLLGASG PickPocket 50000.0 39837.46 0.797 PickPocket 43.0 35.0 101 0.891 NA NA NA NA NA NA 50000.0 39837.46 0.797 43.0 35.0 NA NA NA NA 39837.46 50000.0 35.0 43.0 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 1.6571428571428568 2.9142857142857146 False False False 0 False 0 +4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 Not Run Not Run protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-G*01:09 10 2 10 ASAAAAAAAV ASAAAAAAAA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 128 0.977 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A False 2.142857142857143 2.142857142857143 False False False 0 False 0 +4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 Not Run Not Run protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-G*01:09 10 3 1 SAAAAAAAVI AAAAAAAAVI PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 128 0.977 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A False 2.5285714285714285 2.5285714285714285 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 2 10 SATLSRTLLL SATLSRTLLA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.3142857142857143 1.3142857142857143 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 4 8 TLSRTLLLAA TLSRTLLAAA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.4 1.4 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 5 7, 10 LSRTLLLAAA LSRTLLAAAG PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 2.3000000000000003 2.3000000000000003 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-G*01:09 10 6 1, 2, 3, 4 SRTLLLAAAG LSRTLLAAAG PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 76 0.158 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 2.342857142857143 2.342857142857143 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 2 9 SGGSHVWTHS SGGSHVWTRS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H False -0.7714285714285714 -0.31428571428571433 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 3 8 GGSHVWTHSR GGSHVWTRSR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H False -1.3000000000000003 -0.31428571428571433 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 5 6 SHVWTHSRDP SHVWTRSRDP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1714285714285717 -0.7714285714285714 False False True 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 9 2 THSRDPEGSS TRSRDPEGSS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 10 10 1 HSRDPEGSSR RSRDPEGSSR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 56 0.071 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 5.CECR2.ENST00000262608.8.missense.535R/H False -2.1571428571428575 -2.1571428571428575 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 1 10 QKAVRPLELV QKAVRPLELA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.9142857142857144 0.9142857142857144 True False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 2 9 KAVRPLELVY KAVRPLELAY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.1285714285714286 0.9142857142857144 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 6 5 PLELVYCLQK PLELAYCLQK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.7999999999999999 1.9000000000000001 False False False 1 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 7 4 LELVYCLQKC LELAYCLQKC PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V False 0.6142857142857141 1.9000000000000001 False True False 2 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 10 8 3 ELVYCLQKCN ELAYCLQKCN PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.053 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 6.USP18.ENST00000215794.7.missense.124A/V False -0.4857142857142857 0.8571428571428571 True False False 2 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 1 10 NKSVNEALNN NKSVNEALNH PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6 -0.21428571428571427 False False False 0 True 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 5 6 NEALNNLLTE NEALNHLLTE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True 0.02857142857142847 0.7857142857142856 False False False 0 True 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 6 5 EALNNLLTEE EALNHLLTEE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.7857142857142856 True False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 8 3 LNNLLTEEED LNHLLTEEED PickPocket 50000.0 22451.54 0.449 PickPocket 43.0 18.0 30 0.1 NA NA NA NA NA NA 50000.0 22451.54 0.449 43.0 18.0 NA NA NA NA 22451.54 50000.0 18.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.0142857142857145 0.02857142857142847 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 10 9 2 NNLLTEEEDY NHLLTEEEDY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 30 0.1 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -1.742857142857143 -1.0142857142857145 False False False 0 True 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 1 10 EDAVQGIANQ EDAVQGIANE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.0571428571428572 0.7000000000000001 True False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 2 9 DAVQGIANQD DAVQGIANED PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.157142857142857 0.7000000000000001 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 4 7 VQGIANQDAA VQGIANEDAA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.08571428571428576 -0.0571428571428572 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 5 6 QGIANQDAAQ QGIANEDAAQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.2285714285714284 -0.08571428571428576 True False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 6 5 GIANQDAAQG GIANEDAAQG PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -1.5428571428571427 -0.08571428571428576 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 7 4 IANQDAAQGI IANEDAAQGI PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 -0.08571428571428576 False False False 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 9 2 NQDAAQGIAK NEDAAQGIAK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False 0.3 0.35714285714285715 False False False 0 True 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 10 10 1 QDAAQGIAKE EDAAQGIAKE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 22 0.5 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.45714285714285713 0.35714285714285715 True False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 1 10 GKTVTISCTG GKTVTISCTR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 1.2285714285714284 1.2285714285714284 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 3 8 TVTISCTGSS TVTISCTRSS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.5 1.2285714285714284 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 5 6 TISCTGSSGS TISCTRSSGS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.20000000000000004 0.5142857142857142 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 7 4 SCTGSSGSIA SCTRSSGSIA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.4428571428571428 0.4428571428571428 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 8 3 CTGSSGSIAS CTRSSGSIAS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.38571428571428573 0.4428571428571428 True False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 9 2 TGSSGSIASN TRSSGSIASN PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 5 1.0 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 0.0 0.4428571428571428 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 10 10 1 GSSGSIASNY RSSGSIASNY PickPocket 50000.0 33504.88 0.67 PickPocket 43.0 29.0 5 1.0 NA NA NA NA NA NA 50000.0 33504.88 0.67 43.0 29.0 NA NA NA NA 33504.88 50000.0 29.0 43.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False -0.07142857142857147 0.4428571428571428 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 7 4 PGSAPTTVIY PGSSPTTVIY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.8857142857142858 0.9571428571428572 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 8 3 GSAPTTVIYE GSSPTTVIYE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False 0.12857142857142861 0.9571428571428572 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 10 10 1 APTTVIYEDN SPTTVIYEDN PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 7 0.571 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.5428571428571428 0.8857142857142858 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 3 8 HEDLIGKHGG HEDLIGKPGG PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H False -3.172065784643304e-17 -3.172065784643304e-17 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 4 7 EDLIGKHGGV EDLIGKPGGV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.05714285714285713 0.05714285714285713 True False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 5 6 DLIGKHGGVS DLIGKPGGVS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.7000000000000001 0.05714285714285713 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 7 4 IGKHGGVSLS IGKPGGVSLS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.3428571428571429 0.3428571428571429 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 8 3 GKHGGVSLSK GKPGGVSLSK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.24285714285714294 0.3428571428571429 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-G*01:09 10 10 1 HGGVSLSKIE PGGVSLSKIE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 140 0.179 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.5 0.9428571428571428 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 2 9 SPVKEEEKTQ SPVKEEEKPQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T False -3.2142857142857144 -1.8 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 3 8 PVKEEEKTQE PVKEEEKPQE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T False -3.1571428571428575 -2.1142857142857143 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 4 7 VKEEEKTQEV VKEEEKPQEV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.0571428571428574 -2.0571428571428574 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 5 6 KEEEKTQEVK KEEEKPQEVK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T False -2.1142857142857143 -2.0571428571428574 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 6 5 EEEKTQEVKV EEEKPQEVKV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.014285714285714 -1.014285714285714 True False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 7 4 EEKTQEVKVK EEKPQEVKVK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.0142857142857142 -1.014285714285714 True False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 8 3 EKTQEVKVKE EKPQEVKVKE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.4142857142857141 -1.014285714285714 True False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 10 10 1 TQEVKVKEPP PQEVKVKEPP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 185 0.038 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 12.NEFH.ENST00000310624.6.missense.830P/T False -0.8714285714285713 -0.8714285714285713 False False True 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 3 8 VCELAGNLFN VCELAGNPFN PickPocket 50000.0 43911.91 0.878 PickPocket 43.0 38.0 303 0.135 NA NA NA NA NA NA 50000.0 43911.91 0.878 43.0 38.0 NA NA NA NA 43911.91 50000.0 38.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6857142857142856 0.7000000000000001 False False False 1 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 4 7 CELAGNLFNC CELAGNPFNC PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.5 0.6857142857142856 True True False 2 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 5 6 ELAGNLFNCE ELAGNPFNCE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L False -0.2571428571428572 0.6857142857142856 True False False 1 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 6 5 LAGNLFNCEC LAGNPFNCEC PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.6857142857142856 False True False 2 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 10 7 4 AGNLFNCECD AGNPFNCECD PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 303 0.135 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.15714285714285708 0.5 False False False 2 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 2 9 LHTVSPEPAR LHTVSPEPPR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A False -0.8571428571428571 -0.2571428571428572 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 3 8 HTVSPEPARP HTVSPEPPRP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.6857142857142855 -0.31428571428571433 False False True 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 4 7 TVSPEPARPP TVSPEPPRPP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.7999999999999996 -0.31428571428571433 False False True 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 6 5 SPEPARPPQQ SPEPPRPPQQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -1.6857142857142855 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 7 4 PEPARPPQQP PEPPRPPQQP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A False -2.0714285714285716 -1.7999999999999996 False False True 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 8 3 EPARPPQQPV EPPRPPQQPV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.7285714285714289 -1.7285714285714289 True False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 9 2 PARPPQQPVP PPRPPQQPVP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-G*01:09 10 10 1 ARPPQQPVPT PRPPQQPVPT PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 245 0.486 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 15.GGA1.ENST00000343632.4.missense.484P/A False -1.1857142857142855 -1.1857142857142855 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 2 10 TGGGGRSAGS TGGGGRSAGQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.7857142857142857 -0.7285714285714285 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 3 9, 10 GGGGRSAGST GGGGRSAGQH PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8285714285714286 -0.7285714285714285 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 4 8, 9, 10 GGGRSAGSTG GGGRSAGQHW PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8285714285714286 -0.7285714285714286 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 5 7, 8, 9, 10 GGRSAGSTGQ GGRSAGQHWA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6857142857142857 -0.6857142857142857 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 6 6, 7, 8, 9, 10 GRSAGSTGQG GRSAGQHWAR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 142 0.768 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6285714285714287 -0.6285714285714287 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 8 NA SAGSTGQGSG NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0000000000000002 -0.6285714285714287 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 9 NA AGSTGQGSGE NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.3857142857142857 -0.6285714285714287 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 10 NA GSTGQGSGEK NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.842857142857143 -1.0000000000000002 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 11 NA STGQGSGEKA NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.5285714285714287 -1.0000000000000002 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 12 NA TGQGSGEKAG NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -1.0857142857142859 -1.0857142857142859 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 13 NA GQGSGEKAGC NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.6714285714285715 -0.6714285714285715 False True False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 14 NA QGSGEKAGCP NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.7857142857142857 -0.6714285714285715 True False True 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 15 NA GSGEKAGCPW NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.8571428571428574 -0.6714285714285715 False False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 17 NA GEKAGCPWSG NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False 0.02857142857142855 0.02857142857142855 False False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 18 NA EKAGCPWSGT NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.32857142857142857 0.02857142857142855 True False False 1 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 10 19 NA KAGCPWSGTG NA PickPocket 50000.0 NA NA PickPocket 43.0 NA 142 0.768 NA NA NA NA NA NA 50000.0 NA NA 43.0 NA NA NA NA NA NA 50000.0 NA 43.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.3285714285714286 0.02857142857142855 False False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 3 8 QPCDDMDYLS QPCDDMDCLS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.9857142857142858 -0.5142857142857142 True False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 4 7 PCDDMDYLSD PCDDMDCLSD PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.9857142857142857 -0.5142857142857142 False False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 5 6 CDDMDYLSDR CDDMDCLSDR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.1285714285714286 -0.5142857142857142 True False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 6 5 DDMDYLSDRC DDMDCLSDRC PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.042857142857143 -0.9857142857142857 False True False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 7 4 DMDYLSDRCK DMDCLSDRCK PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.0999999999999999 -0.9857142857142857 False False False 1 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 10 1 YLSDRCKILQ CLSDRCKILQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 92 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -0.6571428571428573 -0.27142857142857146 False False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 4 7 CQRAKVEMSH CQRAKVAMSH PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.044 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.5 -0.5 True False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 5 6 QRAKVEMSHF QRAKVAMSHF PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.044 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.35714285714285715 -0.35714285714285715 True False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 6 5 RAKVEMSHFE RAKVAMSHFE PickPocket 50000.0 49461.93 0.989 PickPocket 43.0 42.0 113 0.044 NA NA NA NA NA NA 50000.0 49461.93 0.989 43.0 42.0 NA NA NA NA 49461.93 50000.0 42.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E False -0.3000000000000001 -0.3000000000000001 False False False 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 7 4 AKVEMSHFEP AKVAMSHFEP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 113 0.044 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.1285714285714286 -0.3000000000000001 False False True 0 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 10 10 1 EMSHFEPNEY AMSHFEPNEY PickPocket 50000.0 36141.06 0.723 PickPocket 43.0 32.0 113 0.044 NA NA NA NA NA NA 50000.0 36141.06 0.723 43.0 32.0 NA NA NA NA 36141.06 50000.0 32.0 43.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.9714285714285715 -1.1285714285714286 True False False 0 False 0 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 1 10 IAGTLKFNPQ IAGTLKFNPE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.942857142857143 1.1285714285714286 False False False 0 False 1 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 2 9 AGTLKFNPQT AGTLKFNPET PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.942857142857143 -0.0142857142857143 False False False 0 False 1 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 4 7 TLKFNPQTDY TLKFNPETDY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.6142857142857143 -0.942857142857143 False False False 0 False 1 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 8 3 NPQTDYLTGT NPETDYLTGT PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.5 -0.5 False False False 0 True 1 +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 10 9 2 PQTDYLTGTD PETDYLTGTD PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 136 0.25 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 19.ACO2.ENST00000216254.4.missense.510E/Q False -0.9 -0.5 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 1 10 SAKTTVVVTT SAKTTVVVTA PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.4000000000000001 1.4000000000000001 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 2 9 AKTTVVVTTQ AKTTVVVTAQ PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.0000000000000002 1.4000000000000001 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 4 7 TTVVVTTQKR TTVVVTAQKR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -0.7000000000000001 1.4000000000000001 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 5 6 TVVVTTQKRN TVVVTAQKRN PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -1.8 1.0000000000000002 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 6 5 VVVTTQKRNS VVVTAQKRNS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -2.5142857142857147 0.5428571428571433 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 7 4 VVTTQKRNSR VVTAQKRNSR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.0571428571428574 -0.7000000000000001 False False False 0 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 10 8 3 VTTQKRNSRR VTAQKRNSRR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 96 0.042 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False -3.6 -1.8 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 1 10 PALGWEFLAF PALGWEFLAS PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 171 0.959 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.9142857142857143 1.0571428571428572 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 3 8 LGWEFLAFTR LGWEFLASTR PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 171 0.959 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.35714285714285704 1.0571428571428572 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 5 6 WEFLAFTRLT WEFLASTRLT PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 171 0.959 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 22.PANX2.ENST00000395842.2.missense.147S/F False 0.8999999999999997 1.4000000000000001 False False False 0 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 10 7 4 FLAFTRLTSE FLASTRLTSE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 171 0.959 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 22.PANX2.ENST00000395842.2.missense.147S/F False -0.5142857142857143 1.4000000000000001 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 1 10 RVSLFGALVR RVSLFGALVH PickPocket 50000.0 39837.46 0.797 PickPocket 43.0 35.0 210 0.686 NA NA NA NA NA NA 50000.0 39837.46 0.797 43.0 35.0 NA NA NA NA 39837.46 50000.0 35.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False 1.6428571428571428 2.1714285714285713 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 4 7 LFGALVRSRT LFGALVHSRT PickPocket 50000.0 45360.65 0.907 PickPocket 43.0 39.0 210 0.686 NA NA NA NA NA NA 50000.0 45360.65 0.907 43.0 39.0 NA NA NA NA 45360.65 50000.0 39.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.09999999999999987 1.6428571428571428 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 5 6 FGALVRSRTY FGALVHSRTY PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -0.5428571428571428 0.9857142857142857 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 6 5 GALVRSRTYD GALVHSRTYD PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.5857142857142856 -0.05714285714285732 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 8 3 LVRSRTYDMD LVHSRTYDMD PickPocket 50000.0 15541.08 0.311 PickPocket 43.0 12.0 210 0.686 NA NA NA NA NA NA 50000.0 15541.08 0.311 43.0 12.0 NA NA NA NA 15541.08 50000.0 12.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.7714285714285716 -0.5428571428571428 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 10 9 2 VRSRTYDMDV VHSRTYDMDV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 210 0.686 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 2 9 EERTEASGYE EERTEASGSE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.2 -1.2 True False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 3 8 ERTEASGYES ERTEASGSES PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.2142857142857142 -1.2 True False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 5 6 TEASGYESRV TEASGSESRV PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.0142857142857145 -1.0142857142857145 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 6 5 EASGYESRVE EASGSESRVE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.4000000000000001 -1.0142857142857145 True False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 7 4 ASGYESRVEP ASGSESRVEP PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.5714285714285712 -1.0142857142857145 False False True 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 10 10 1 YESRVEPPHE SESRVEPPHE PickPocket 50000.0 50000.0 1.0 PickPocket 43.0 43.0 116 0.043 NA NA NA NA NA NA 50000.0 50000.0 1.0 43.0 43.0 NA NA NA NA 50000.0 50000.0 43.0 43.0 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.957142857142857 -1.5714285714285712 False False False 0 False 0 diff --git a/tests/test_data/top_score_filter/input_pvacsplice.tsv b/tests/test_data/top_score_filter/input_pvacsplice.tsv index ac40759d3..f52875919 100644 --- a/tests/test_data/top_score_filter/input_pvacsplice.tsv +++ b/tests/test_data/top_score_filter/input_pvacsplice.tsv @@ -1,449 +1,449 @@ -Chromosome Start Stop Reference Variant Junction Junction Start Junction Stop Junction Score Junction Anchor Transcript Transcript Support Level Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Amino Acid Change Gene Name HGVSc HGVSp WT Protein Length ALT Protein Length Frameshift Event Protein Position HLA Allele Peptide Length Epitope Seq Median IC50 Score Best IC50 Score Best IC50 Score Method Median Percentile Best Percentile Best Percentile Method Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Index Fasta Key NetMHC IC50 Score NetMHC Percentile PickPocket IC50 Score PickPocket Percentile Problematic Positions cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 38 HLA-E*01:01 9 FKNPAWVWL 12055.8 6262.79 PickPocket 6.95 1.9 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 37 17848.81 1.9 6262.79 12.0 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 38 HLA-E*01:01 9 FKNPAWVWL 12055.8 6262.79 PickPocket 6.95 1.9 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 37 17848.81 1.9 6262.79 12.0 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-E*01:01 9 KNPAWVWLW 11362.895 3975.68 PickPocket 3.25 2.3 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 38 18750.11 2.3 3975.68 4.2 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-E*01:01 9 KNPAWVWLW 11362.895 3975.68 PickPocket 3.25 2.3 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 38 18750.11 2.3 3975.68 4.2 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-E*01:01 9 IMKSADVVN 14932.635 2842.78 PickPocket 4.2 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 25 27022.49 6.6 2842.78 1.8 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-E*01:01 9 IMKSADVVN 14932.635 2842.78 PickPocket 4.2 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 25 27022.49 6.6 2842.78 1.8 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 35 HLA-E*01:01 9 KQRFKNPAW 14692.5 1765.99 PickPocket 3.8 0.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 34 27619.01 7.1 1765.99 0.5 None -1.4 -1.4 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 35 HLA-E*01:01 9 KQRFKNPAW 14692.5 1765.99 PickPocket 3.8 0.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 34 27619.01 7.1 1765.99 0.5 None -1.4 -1.4 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 720 HLA-E*01:01 9 EETIKVYCL 21541.42 14407.49 PickPocket 23.6 8.2 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 3 28675.35 8.2 14407.49 39.0 8 1.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 720 HLA-E*01:01 9 EETIKVYCL 21541.42 14407.49 PickPocket 23.6 8.2 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 3 28675.35 8.2 14407.49 39.0 8 1.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 721 HLA-E*01:01 9 EETIKVYCL 21541.42 14407.49 PickPocket 23.6 8.2 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 3 28675.35 8.2 14407.49 39.0 8 1.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 721 HLA-E*01:01 9 EETIKVYCL 21541.42 14407.49 PickPocket 23.6 8.2 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 3 28675.35 8.2 14407.49 39.0 8 1.3 1.3 True False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-E*01:01 9 RFKNPAWVW 19244.85 8950.22 PickPocket 15.1 9.2 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 36 29539.48 9.2 8950.22 21.0 None -0.6857142857142857 -0.15714285714285708 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-E*01:01 9 RFKNPAWVW 19244.85 8950.22 PickPocket 15.1 9.2 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 36 29539.48 9.2 8950.22 21.0 None -0.6857142857142857 -0.15714285714285708 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 758 HLA-E*01:01 9 KKKSEEKEL 21846.13 11112.54 PickPocket 22.0 15.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 10 32579.72 15.0 11112.54 29.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 758 HLA-E*01:01 9 KKKSEEKEL 21846.13 11112.54 PickPocket 22.0 15.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 10 32579.72 15.0 11112.54 29.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 759 HLA-E*01:01 9 KKKSEEKEL 21846.13 11112.54 PickPocket 22.0 15.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 10 32579.72 15.0 11112.54 29.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 759 HLA-E*01:01 9 KKKSEEKEL 21846.13 11112.54 PickPocket 22.0 15.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 10 32579.72 15.0 11112.54 29.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-E*01:01 9 MKSADVVKV 21064.155 8119.76 PickPocket 18.0 18.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 16 34008.55 18.0 8119.76 18.0 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-E*01:01 9 MKSADVVKV 21064.155 8119.76 PickPocket 18.0 18.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 16 34008.55 18.0 8119.76 18.0 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 34 HLA-E*01:01 9 VKVKCKLTQ 22002.895 9654.43 PickPocket 21.5 19.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 22 34351.36 19.0 9654.43 24.0 5 -0.21428571428571427 0.42857142857142855 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 34 HLA-E*01:01 9 VKVKCKLTQ 22002.895 9654.43 PickPocket 21.5 19.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 22 34351.36 19.0 9654.43 24.0 5 -0.21428571428571427 0.42857142857142855 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 36 HLA-E*01:01 9 VKCKLTQSF 30370.74 25842.4 PickPocket 42.0 20.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 24 34899.08 20.0 25842.4 64.0 3 0.028571428571428532 0.028571428571428532 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 36 HLA-E*01:01 9 VKCKLTQSF 30370.74 25842.4 PickPocket 42.0 20.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 24 34899.08 20.0 25842.4 64.0 3 0.028571428571428532 0.028571428571428532 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 724 HLA-E*01:01 9 KVYCLQKEL 31283.235 26694.99 PickPocket 44.5 23.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 7 35871.48 23.0 26694.99 66.0 4 -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 724 HLA-E*01:01 9 KVYCLQKEL 31283.235 26694.99 PickPocket 44.5 23.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 7 35871.48 23.0 26694.99 66.0 4 -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-E*01:01 9 KVYCLQKEL 31283.235 26694.99 PickPocket 44.5 23.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 7 35871.48 23.0 26694.99 66.0 4 -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-E*01:01 9 KVYCLQKEL 31283.235 26694.99 PickPocket 44.5 23.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 7 35871.48 23.0 26694.99 66.0 4 -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 33 HLA-E*01:01 9 VVKVKCKLT 25527.395 14882.82 PickPocket 32.0 24.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 21 36171.97 24.0 14882.82 40.0 6 -0.27142857142857146 0.4857142857142856 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 33 HLA-E*01:01 9 VVKVKCKLT 25527.395 14882.82 PickPocket 32.0 24.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 21 36171.97 24.0 14882.82 40.0 6 -0.27142857142857146 0.4857142857142856 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 40 HLA-E*01:01 9 NPAWVWLWN 28278.445 19295.7 PickPocket 39.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 39 37261.19 28.0 19295.7 51.0 None 0.5142857142857142 0.7857142857142857 False False False 0 True 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 40 HLA-E*01:01 9 NPAWVWLWN 28278.445 19295.7 PickPocket 39.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 39 37261.19 28.0 19295.7 51.0 None 0.5142857142857142 0.7857142857142857 False False False 0 True 1 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 32 HLA-E*01:01 9 DVVKVKCKL 42650.475 37418.75 NetMHC 57.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 20 37418.75 28.0 47882.2 87.0 7 0.42857142857142855 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 32 HLA-E*01:01 9 DVVKVKCKL 42650.475 37418.75 NetMHC 57.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 20 37418.75 28.0 47882.2 87.0 7 0.42857142857142855 0.542857142857143 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-E*01:01 9 VSEETIKVY 26913.29 16404.99 PickPocket 36.0 28.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 1 37421.59 28.0 16404.99 44.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-E*01:01 9 VSEETIKVY 26913.29 16404.99 PickPocket 36.0 28.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 1 37421.59 28.0 16404.99 44.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-E*01:01 9 VSEETIKVY 26913.29 16404.99 PickPocket 36.0 28.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 1 37421.59 28.0 16404.99 44.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-E*01:01 9 VSEETIKVY 26913.29 16404.99 PickPocket 36.0 28.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 1 37421.59 28.0 16404.99 44.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 33 HLA-E*01:01 9 VVKQRFKNP 25924.465 14407.49 PickPocket 33.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 32 37441.44 28.0 14407.49 39.0 None -2.585714285714286 -0.6571428571428571 False False True 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 33 HLA-E*01:01 9 VVKQRFKNP 25924.465 14407.49 PickPocket 33.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 32 37441.44 28.0 14407.49 39.0 None -2.585714285714286 -0.6571428571428571 False False True 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 28 HLA-E*01:01 9 MKSADVVKQ 22469.835 7366.35 PickPocket 22.5 16.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 27 37573.32 29.0 7366.35 16.0 None -0.21428571428571422 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 28 HLA-E*01:01 9 MKSADVVKQ 22469.835 7366.35 PickPocket 22.5 16.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 27 37573.32 29.0 7366.35 16.0 None -0.21428571428571422 0.5571428571428572 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 12 37753.86 30.0 2812.19 1.7 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 12 37753.86 30.0 2812.19 1.7 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 12 37753.86 30.0 2812.19 1.7 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 12 37753.86 30.0 2812.19 1.7 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 756 HLA-E*01:01 9 QLKKKSEEK 25845.025 13648.77 PickPocket 34.0 31.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 8 38041.28 31.0 13648.77 37.0 None -3.3428571428571425 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 756 HLA-E*01:01 9 QLKKKSEEK 25845.025 13648.77 PickPocket 34.0 31.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 8 38041.28 31.0 13648.77 37.0 None -3.3428571428571425 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 757 HLA-E*01:01 9 QLKKKSEEK 25845.025 13648.77 PickPocket 34.0 31.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 8 38041.28 31.0 13648.77 37.0 None -3.3428571428571425 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 757 HLA-E*01:01 9 QLKKKSEEK 25845.025 13648.77 PickPocket 34.0 31.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 8 38041.28 31.0 13648.77 37.0 None -3.3428571428571425 -2.242857142857143 True False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 28 HLA-E*01:01 9 MKSADVVNR 24046.41 8758.62 PickPocket 29.0 21.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 26 39334.2 37.0 8758.62 21.0 None -0.29999999999999993 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 28 HLA-E*01:01 9 MKSADVVNR 24046.41 8758.62 PickPocket 29.0 21.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 26 39334.2 37.0 8758.62 21.0 None -0.29999999999999993 0.5571428571428572 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 723 HLA-E*01:01 9 IKVYCLQKE 29432.01 18279.56 PickPocket 46.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 6 40584.46 44.0 18279.56 49.0 5 -0.24285714285714294 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 723 HLA-E*01:01 9 IKVYCLQKE 29432.01 18279.56 PickPocket 46.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 6 40584.46 44.0 18279.56 49.0 5 -0.24285714285714294 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 724 HLA-E*01:01 9 IKVYCLQKE 29432.01 18279.56 PickPocket 46.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 6 40584.46 44.0 18279.56 49.0 5 -0.24285714285714294 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 724 HLA-E*01:01 9 IKVYCLQKE 29432.01 18279.56 PickPocket 46.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 6 40584.46 44.0 18279.56 49.0 5 -0.24285714285714294 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 722 HLA-E*01:01 9 TIKVYCLQK 24506.46 8297.38 PickPocket 31.5 19.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 5 40715.54 44.0 8297.38 19.0 6 -0.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 722 HLA-E*01:01 9 TIKVYCLQK 24506.46 8297.38 PickPocket 31.5 19.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 5 40715.54 44.0 8297.38 19.0 6 -0.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 723 HLA-E*01:01 9 TIKVYCLQK 24506.46 8297.38 PickPocket 31.5 19.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 5 40715.54 44.0 8297.38 19.0 6 -0.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 723 HLA-E*01:01 9 TIKVYCLQK 24506.46 8297.38 PickPocket 31.5 19.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 5 40715.54 44.0 8297.38 19.0 6 -0.3 1.3 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 36 HLA-E*01:01 9 QRFKNPAWV 43078.875 40797.1 NetMHC 65.5 45.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 35 40797.1 45.0 45360.65 86.0 None -0.15714285714285708 -0.15714285714285708 True False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 36 HLA-E*01:01 9 QRFKNPAWV 43078.875 40797.1 NetMHC 65.5 45.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 35 40797.1 45.0 45360.65 86.0 None -0.15714285714285708 -0.15714285714285708 True False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 34 HLA-E*01:01 9 VKQRFKNPA 36594.955 32085.75 PickPocket 60.5 47.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 33 41104.16 47.0 32085.75 74.0 None -1.7714285714285711 -1.757142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 34 HLA-E*01:01 9 VKQRFKNPA 36594.955 32085.75 PickPocket 60.5 47.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 33 41104.16 47.0 32085.75 74.0 None -1.7714285714285711 -1.757142857142857 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 759 HLA-E*01:01 9 KKSEEKELK 30625.595 19088.05 PickPocket 53.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 11 42163.14 55.0 19088.05 51.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 759 HLA-E*01:01 9 KKSEEKELK 30625.595 19088.05 PickPocket 53.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 11 42163.14 55.0 19088.05 51.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 760 HLA-E*01:01 9 KKSEEKELK 30625.595 19088.05 PickPocket 53.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 11 42163.14 55.0 19088.05 51.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 760 HLA-E*01:01 9 KKSEEKELK 30625.595 19088.05 PickPocket 53.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 11 42163.14 55.0 19088.05 51.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 721 HLA-E*01:01 9 ETIKVYCLQ 46120.845 42241.69 NetMHC 72.0 56.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 4 42241.69 56.0 50000.0 88.0 7 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 721 HLA-E*01:01 9 ETIKVYCLQ 46120.845 42241.69 NetMHC 72.0 56.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 4 42241.69 56.0 50000.0 88.0 7 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 722 HLA-E*01:01 9 ETIKVYCLQ 46120.845 42241.69 NetMHC 72.0 56.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 4 42241.69 56.0 50000.0 88.0 7 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 722 HLA-E*01:01 9 ETIKVYCLQ 46120.845 42241.69 NetMHC 72.0 56.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 4 42241.69 56.0 50000.0 88.0 7 0.9000000000000001 1.3 True False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 30 HLA-E*01:01 9 SADVVKQRF 37899.345 33504.88 PickPocket 65.5 56.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 29 42293.81 56.0 33504.88 75.0 None -0.6 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 30 HLA-E*01:01 9 SADVVKQRF 37899.345 33504.88 PickPocket 65.5 56.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 29 42293.81 56.0 33504.88 75.0 None -0.6 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 32 HLA-E*01:01 9 DVVKQRFKN 35416.435 28485.48 PickPocket 63.0 57.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 31 42347.39 57.0 28485.48 69.0 None -1.757142857142857 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 32 HLA-E*01:01 9 DVVKQRFKN 35416.435 28485.48 PickPocket 63.0 57.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 31 42347.39 57.0 28485.48 69.0 None -1.757142857142857 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 29 HLA-E*01:01 9 KSADVVKVK 28151.725 13947.35 PickPocket 47.0 37.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 17 42356.1 57.0 13947.35 37.0 None 0.4428571428571429 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 29 HLA-E*01:01 9 KSADVVKVK 28151.725 13947.35 PickPocket 47.0 37.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 17 42356.1 57.0 13947.35 37.0 None 0.4428571428571429 0.8857142857142859 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 757 HLA-E*01:01 9 LKKKSEEKE 27609.175 12653.21 PickPocket 46.0 34.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 9 42565.14 58.0 12653.21 34.0 None -3.2857142857142856 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 757 HLA-E*01:01 9 LKKKSEEKE 27609.175 12653.21 PickPocket 46.0 34.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 9 42565.14 58.0 12653.21 34.0 None -3.2857142857142856 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 758 HLA-E*01:01 9 LKKKSEEKE 27609.175 12653.21 PickPocket 46.0 34.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 9 42565.14 58.0 12653.21 34.0 None -3.2857142857142856 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 758 HLA-E*01:01 9 LKKKSEEKE 27609.175 12653.21 PickPocket 46.0 34.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 9 42565.14 58.0 12653.21 34.0 None -3.2857142857142856 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 761 HLA-E*01:01 9 SEEKELKIK 42009.35 41151.77 PickPocket 72.0 61.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 13 42866.93 61.0 41151.77 83.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 761 HLA-E*01:01 9 SEEKELKIK 42009.35 41151.77 PickPocket 72.0 61.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 13 42866.93 61.0 41151.77 83.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 762 HLA-E*01:01 9 SEEKELKIK 42009.35 41151.77 PickPocket 72.0 61.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 13 42866.93 61.0 41151.77 83.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 762 HLA-E*01:01 9 SEEKELKIK 42009.35 41151.77 PickPocket 72.0 61.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 13 42866.93 61.0 41151.77 83.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 31 HLA-E*01:01 9 ADVVKQRFK 30344.565 17316.93 PickPocket 56.5 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 30 43372.2 66.0 17316.93 47.0 None -0.6571428571428571 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 31 HLA-E*01:01 9 ADVVKQRFK 30344.565 17316.93 PickPocket 56.5 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 30 43372.2 66.0 17316.93 47.0 None -0.6571428571428571 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 31 HLA-E*01:01 9 ADVVKVKCK 28952.59 14407.49 PickPocket 53.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 19 43497.69 67.0 14407.49 39.0 8 0.4857142857142856 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 31 HLA-E*01:01 9 ADVVKVKCK 28952.59 14407.49 PickPocket 53.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 19 43497.69 67.0 14407.49 39.0 8 0.4857142857142856 0.542857142857143 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 719 HLA-E*01:01 9 SEETIKVYC 37717.65 31740.46 PickPocket 71.0 69.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 2 43694.84 69.0 31740.46 73.0 9 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 719 HLA-E*01:01 9 SEETIKVYC 37717.65 31740.46 PickPocket 71.0 69.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 2 43694.84 69.0 31740.46 73.0 9 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 720 HLA-E*01:01 9 SEETIKVYC 37717.65 31740.46 PickPocket 71.0 69.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 2 43694.84 69.0 31740.46 73.0 9 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 720 HLA-E*01:01 9 SEETIKVYC 37717.65 31740.46 PickPocket 71.0 69.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 2 43694.84 69.0 31740.46 73.0 9 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 29 HLA-E*01:01 9 KSADVVKQR 29130.49 14564.23 PickPocket 54.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 28 43696.75 69.0 14564.23 39.0 None -0.7428571428571428 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 29 HLA-E*01:01 9 KSADVVKQR 29130.49 14564.23 PickPocket 54.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 28 43696.75 69.0 14564.23 39.0 None -0.7428571428571428 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 35 HLA-E*01:01 9 KVKCKLTQS 32815.365 21734.48 PickPocket 64.0 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 23 43896.25 71.0 21734.48 57.0 4 -0.9285714285714286 -0.21428571428571427 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 35 HLA-E*01:01 9 KVKCKLTQS 32815.365 21734.48 PickPocket 64.0 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 23 43896.25 71.0 21734.48 57.0 4 -0.9285714285714286 -0.21428571428571427 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 763 HLA-E*01:01 9 EKELKIKNH 33564.085 22942.68 PickPocket 66.5 59.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 15 44185.49 74.0 22942.68 59.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 763 HLA-E*01:01 9 EKELKIKNH 33564.085 22942.68 PickPocket 66.5 59.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 15 44185.49 74.0 22942.68 59.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 764 HLA-E*01:01 9 EKELKIKNH 33564.085 22942.68 PickPocket 66.5 59.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 15 44185.49 74.0 22942.68 59.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 764 HLA-E*01:01 9 EKELKIKNH 33564.085 22942.68 PickPocket 66.5 59.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 15 44185.49 74.0 22942.68 59.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 30 HLA-E*01:01 9 SADVVKVKC 38984.985 33504.88 PickPocket 76.0 75.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 18 44465.09 77.0 33504.88 75.0 9 0.542857142857143 0.8857142857142859 False True False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 30 HLA-E*01:01 9 SADVVKVKC 38984.985 33504.88 PickPocket 76.0 75.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 18 44465.09 77.0 33504.88 75.0 9 0.542857142857143 0.8857142857142859 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 762 HLA-E*01:01 9 EEKELKIKN 37817.35 30726.73 PickPocket 77.0 72.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 14 44907.97 82.0 30726.73 72.0 None -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 762 HLA-E*01:01 9 EEKELKIKN 37817.35 30726.73 PickPocket 77.0 72.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 14 44907.97 82.0 30726.73 72.0 None -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 763 HLA-E*01:01 9 EEKELKIKN 37817.35 30726.73 PickPocket 77.0 72.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 14 44907.97 82.0 30726.73 72.0 None -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 763 HLA-E*01:01 9 EEKELKIKN 37817.35 30726.73 PickPocket 77.0 72.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 14 44907.97 82.0 30726.73 72.0 None -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 724 HLA-G*01:09 9 KVYCLQKEL 645.63 645.63 PickPocket 0.2 0.2 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 7 NA NA 645.63 0.2 4 -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 724 HLA-G*01:09 9 KVYCLQKEL 645.63 645.63 PickPocket 0.2 0.2 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 7 NA NA 645.63 0.2 4 -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-G*01:09 9 KVYCLQKEL 645.63 645.63 PickPocket 0.2 0.2 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 7 NA NA 645.63 0.2 4 -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-G*01:09 9 KVYCLQKEL 645.63 645.63 PickPocket 0.2 0.2 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 7 NA NA 645.63 0.2 4 -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-G*01:09 9 KNPAWVWLW 5099.03 5099.03 PickPocket 7.5 7.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 38 NA NA 5099.03 7.5 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-G*01:09 9 KNPAWVWLW 5099.03 5099.03 PickPocket 7.5 7.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 38 NA NA 5099.03 7.5 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-G*01:09 9 RFKNPAWVW 9447.76 9447.76 PickPocket 19.0 19.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 36 NA NA 9447.76 19.0 None -0.6857142857142857 -0.15714285714285708 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-G*01:09 9 RFKNPAWVW 9447.76 9447.76 PickPocket 19.0 19.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 36 NA NA 9447.76 19.0 None -0.6857142857142857 -0.15714285714285708 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 9759.45 20.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 9759.45 20.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 9759.45 20.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 9759.45 20.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 35 HLA-G*01:09 9 KQRFKNPAW 12653.21 12653.21 PickPocket 26.0 26.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 34 NA NA 12653.21 26.0 None -1.4 -1.4 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 35 HLA-G*01:09 9 KQRFKNPAW 12653.21 12653.21 PickPocket 26.0 26.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 34 NA NA 12653.21 26.0 None -1.4 -1.4 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-G*01:09 9 IMKSADVVN 16053.81 16053.81 PickPocket 33.0 33.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 25 NA NA 16053.81 33.0 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-G*01:09 9 IMKSADVVN 16053.81 16053.81 PickPocket 33.0 33.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 25 NA NA 16053.81 33.0 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 38 HLA-G*01:09 9 FKNPAWVWL 16583.46 16583.46 PickPocket 34.0 34.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 37 NA NA 16583.46 34.0 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 38 HLA-G*01:09 9 FKNPAWVWL 16583.46 16583.46 PickPocket 34.0 34.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 37 NA NA 16583.46 34.0 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 35 HLA-G*01:09 9 KVKCKLTQS 21734.48 21734.48 PickPocket 44.0 44.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 23 NA NA 21734.48 44.0 4 -0.9285714285714286 -0.21428571428571427 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 35 HLA-G*01:09 9 KVKCKLTQS 21734.48 21734.48 PickPocket 44.0 44.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 23 NA NA 21734.48 44.0 4 -0.9285714285714286 -0.21428571428571427 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 36 HLA-G*01:09 9 QRFKNPAWV 22209.93 22209.93 PickPocket 44.0 44.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 35 NA NA 22209.93 44.0 None -0.15714285714285708 -0.15714285714285708 True False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 36 HLA-G*01:09 9 QRFKNPAWV 22209.93 22209.93 PickPocket 44.0 44.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 35 NA NA 22209.93 44.0 None -0.15714285714285708 -0.15714285714285708 True False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 719 HLA-G*01:09 9 SEETIKVYC 23192.26 23192.26 PickPocket 46.0 46.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 2 NA NA 23192.26 46.0 9 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 719 HLA-G*01:09 9 SEETIKVYC 23192.26 23192.26 PickPocket 46.0 46.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 2 NA NA 23192.26 46.0 9 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 720 HLA-G*01:09 9 SEETIKVYC 23192.26 23192.26 PickPocket 46.0 46.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 2 NA NA 23192.26 46.0 9 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 720 HLA-G*01:09 9 SEETIKVYC 23192.26 23192.26 PickPocket 46.0 46.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 2 NA NA 23192.26 46.0 9 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 30 HLA-G*01:09 9 SADVVKQRF 23699.6 23699.6 PickPocket 47.0 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 29 NA NA 23699.6 47.0 None -0.6 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 30 HLA-G*01:09 9 SADVVKQRF 23699.6 23699.6 PickPocket 47.0 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 29 NA NA 23699.6 47.0 None -0.6 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 29 HLA-G*01:09 9 KSADVVKVK 23957.42 23957.42 PickPocket 47.0 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 17 NA NA 23957.42 47.0 None 0.4428571428571429 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 29 HLA-G*01:09 9 KSADVVKVK 23957.42 23957.42 PickPocket 47.0 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 17 NA NA 23957.42 47.0 None 0.4428571428571429 0.8857142857142859 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 758 HLA-G*01:09 9 KKKSEEKEL 26694.99 26694.99 PickPocket 51.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 10 NA NA 26694.99 51.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 758 HLA-G*01:09 9 KKKSEEKEL 26694.99 26694.99 PickPocket 51.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 10 NA NA 26694.99 51.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 759 HLA-G*01:09 9 KKKSEEKEL 26694.99 26694.99 PickPocket 51.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 10 NA NA 26694.99 51.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 759 HLA-G*01:09 9 KKKSEEKEL 26694.99 26694.99 PickPocket 51.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 10 NA NA 26694.99 51.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 34 HLA-G*01:09 9 VKQRFKNPA 33144.32 33144.32 PickPocket 59.0 59.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 33 NA NA 33144.32 59.0 None -1.7714285714285711 -1.757142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 34 HLA-G*01:09 9 VKQRFKNPA 33144.32 33144.32 PickPocket 59.0 59.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 33 NA NA 33144.32 59.0 None -1.7714285714285711 -1.757142857142857 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 722 HLA-G*01:09 9 TIKVYCLQK 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 5 NA NA 37333.42 64.0 6 -0.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 722 HLA-G*01:09 9 TIKVYCLQK 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 5 NA NA 37333.42 64.0 6 -0.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 723 HLA-G*01:09 9 TIKVYCLQK 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 5 NA NA 37333.42 64.0 6 -0.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 723 HLA-G*01:09 9 TIKVYCLQK 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 5 NA NA 37333.42 64.0 6 -0.3 1.3 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 33 HLA-G*01:09 9 VVKQRFKNP 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 32 NA NA 37333.42 64.0 None -2.585714285714286 -0.6571428571428571 False False True 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 33 HLA-G*01:09 9 VVKQRFKNP 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 32 NA NA 37333.42 64.0 None -2.585714285714286 -0.6571428571428571 False False True 0 False 1 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 36 HLA-G*01:09 9 VKCKLTQSF 38984.65 38984.65 PickPocket 65.0 65.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 24 NA NA 38984.65 65.0 3 0.028571428571428532 0.028571428571428532 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 36 HLA-G*01:09 9 VKCKLTQSF 38984.65 38984.65 PickPocket 65.0 65.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 24 NA NA 38984.65 65.0 3 0.028571428571428532 0.028571428571428532 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 29 HLA-G*01:09 9 KSADVVKQR 41151.77 41151.77 PickPocket 67.0 67.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 28 NA NA 41151.77 67.0 None -0.7428571428571428 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 29 HLA-G*01:09 9 KSADVVKQR 41151.77 41151.77 PickPocket 67.0 67.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 28 NA NA 41151.77 67.0 None -0.7428571428571428 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 33 HLA-G*01:09 9 VVKVKCKLT 43911.91 43911.91 PickPocket 69.0 69.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 21 NA NA 43911.91 69.0 6 -0.27142857142857146 0.4857142857142856 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 33 HLA-G*01:09 9 VVKVKCKLT 43911.91 43911.91 PickPocket 69.0 69.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 21 NA NA 43911.91 69.0 6 -0.27142857142857146 0.4857142857142856 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 721 HLA-G*01:09 9 ETIKVYCLQ 45854.11 45854.11 PickPocket 70.0 70.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 4 NA NA 45854.11 70.0 7 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 721 HLA-G*01:09 9 ETIKVYCLQ 45854.11 45854.11 PickPocket 70.0 70.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 4 NA NA 45854.11 70.0 7 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 722 HLA-G*01:09 9 ETIKVYCLQ 45854.11 45854.11 PickPocket 70.0 70.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 4 NA NA 45854.11 70.0 7 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 722 HLA-G*01:09 9 ETIKVYCLQ 45854.11 45854.11 PickPocket 70.0 70.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 4 NA NA 45854.11 70.0 7 0.9000000000000001 1.3 True False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 30 HLA-G*01:09 9 SADVVKVKC 48929.64 48929.64 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 18 NA NA 48929.64 73.0 9 0.542857142857143 0.8857142857142859 False True False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 30 HLA-G*01:09 9 SADVVKVKC 48929.64 48929.64 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 18 NA NA 48929.64 73.0 9 0.542857142857143 0.8857142857142859 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 720 HLA-G*01:09 9 EETIKVYCL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 3 NA NA 50000.0 73.0 8 1.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 720 HLA-G*01:09 9 EETIKVYCL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 3 NA NA 50000.0 73.0 8 1.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 721 HLA-G*01:09 9 EETIKVYCL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 3 NA NA 50000.0 73.0 8 1.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 721 HLA-G*01:09 9 EETIKVYCL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 3 NA NA 50000.0 73.0 8 1.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 723 HLA-G*01:09 9 IKVYCLQKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 6 NA NA 50000.0 73.0 5 -0.24285714285714294 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 723 HLA-G*01:09 9 IKVYCLQKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 6 NA NA 50000.0 73.0 5 -0.24285714285714294 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 724 HLA-G*01:09 9 IKVYCLQKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 6 NA NA 50000.0 73.0 5 -0.24285714285714294 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 724 HLA-G*01:09 9 IKVYCLQKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 6 NA NA 50000.0 73.0 5 -0.24285714285714294 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 756 HLA-G*01:09 9 QLKKKSEEK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 8 NA NA 50000.0 73.0 None -3.3428571428571425 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 756 HLA-G*01:09 9 QLKKKSEEK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 8 NA NA 50000.0 73.0 None -3.3428571428571425 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 757 HLA-G*01:09 9 QLKKKSEEK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 8 NA NA 50000.0 73.0 None -3.3428571428571425 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 757 HLA-G*01:09 9 QLKKKSEEK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 8 NA NA 50000.0 73.0 None -3.3428571428571425 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 757 HLA-G*01:09 9 LKKKSEEKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 9 NA NA 50000.0 73.0 None -3.2857142857142856 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 757 HLA-G*01:09 9 LKKKSEEKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 9 NA NA 50000.0 73.0 None -3.2857142857142856 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 758 HLA-G*01:09 9 LKKKSEEKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 9 NA NA 50000.0 73.0 None -3.2857142857142856 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 758 HLA-G*01:09 9 LKKKSEEKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 9 NA NA 50000.0 73.0 None -3.2857142857142856 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 759 HLA-G*01:09 9 KKSEEKELK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 11 NA NA 50000.0 73.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 759 HLA-G*01:09 9 KKSEEKELK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 11 NA NA 50000.0 73.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 760 HLA-G*01:09 9 KKSEEKELK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 11 NA NA 50000.0 73.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 760 HLA-G*01:09 9 KKSEEKELK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 11 NA NA 50000.0 73.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 761 HLA-G*01:09 9 SEEKELKIK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 13 NA NA 50000.0 73.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 761 HLA-G*01:09 9 SEEKELKIK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 13 NA NA 50000.0 73.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 762 HLA-G*01:09 9 SEEKELKIK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 13 NA NA 50000.0 73.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 762 HLA-G*01:09 9 SEEKELKIK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 13 NA NA 50000.0 73.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 762 HLA-G*01:09 9 EEKELKIKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 14 NA NA 50000.0 73.0 None -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 762 HLA-G*01:09 9 EEKELKIKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 14 NA NA 50000.0 73.0 None -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 763 HLA-G*01:09 9 EEKELKIKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 14 NA NA 50000.0 73.0 None -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 763 HLA-G*01:09 9 EEKELKIKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 14 NA NA 50000.0 73.0 None -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 763 HLA-G*01:09 9 EKELKIKNH 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 15 NA NA 50000.0 73.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 763 HLA-G*01:09 9 EKELKIKNH 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 15 NA NA 50000.0 73.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 764 HLA-G*01:09 9 EKELKIKNH 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 15 NA NA 50000.0 73.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 764 HLA-G*01:09 9 EKELKIKNH 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 15 NA NA 50000.0 73.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-G*01:09 9 MKSADVVKV 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 16 NA NA 50000.0 73.0 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-G*01:09 9 MKSADVVKV 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 16 NA NA 50000.0 73.0 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 31 HLA-G*01:09 9 ADVVKVKCK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 19 NA NA 50000.0 73.0 8 0.4857142857142856 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 31 HLA-G*01:09 9 ADVVKVKCK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 19 NA NA 50000.0 73.0 8 0.4857142857142856 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 32 HLA-G*01:09 9 DVVKVKCKL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 20 NA NA 50000.0 73.0 7 0.42857142857142855 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 32 HLA-G*01:09 9 DVVKVKCKL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 20 NA NA 50000.0 73.0 7 0.42857142857142855 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 34 HLA-G*01:09 9 VKVKCKLTQ 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 22 NA NA 50000.0 73.0 5 -0.21428571428571427 0.42857142857142855 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 34 HLA-G*01:09 9 VKVKCKLTQ 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 22 NA NA 50000.0 73.0 5 -0.21428571428571427 0.42857142857142855 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 28 HLA-G*01:09 9 MKSADVVNR 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 26 NA NA 50000.0 73.0 None -0.29999999999999993 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 28 HLA-G*01:09 9 MKSADVVNR 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 26 NA NA 50000.0 73.0 None -0.29999999999999993 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 28 HLA-G*01:09 9 MKSADVVKQ 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 27 NA NA 50000.0 73.0 None -0.21428571428571422 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 28 HLA-G*01:09 9 MKSADVVKQ 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 27 NA NA 50000.0 73.0 None -0.21428571428571422 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 31 HLA-G*01:09 9 ADVVKQRFK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 30 NA NA 50000.0 73.0 None -0.6571428571428571 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 31 HLA-G*01:09 9 ADVVKQRFK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 30 NA NA 50000.0 73.0 None -0.6571428571428571 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 32 HLA-G*01:09 9 DVVKQRFKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 31 NA NA 50000.0 73.0 None -1.757142857142857 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 32 HLA-G*01:09 9 DVVKQRFKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 31 NA NA 50000.0 73.0 None -1.757142857142857 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 40 HLA-G*01:09 9 NPAWVWLWN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 39 NA NA 50000.0 73.0 None 0.5142857142857142 0.7857142857142857 False False False 0 True 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 40 HLA-G*01:09 9 NPAWVWLWN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 39 NA NA 50000.0 73.0 None 0.5142857142857142 0.7857142857142857 False False False 0 True 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-E*01:01 10 RFKNPAWVWL 20099.255 12790.86 PickPocket 5.9 4.9 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 39 27407.65 6.9 12790.86 4.9 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-E*01:01 10 RFKNPAWVWL 20099.255 12790.86 PickPocket 5.9 4.9 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 39 27407.65 6.9 12790.86 4.9 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 27 HLA-E*01:01 10 IMKSADVVKV 19498.205 7692.16 PickPocket 7.2 1.4 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 18 31304.25 13.0 7692.16 1.4 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 27 HLA-E*01:01 10 IMKSADVVKV 19498.205 7692.16 PickPocket 7.2 1.4 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 18 31304.25 13.0 7692.16 1.4 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 38 HLA-E*01:01 10 FKNPAWVWLW 30662.99 26985.39 PickPocket 22.0 19.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 40 34340.59 19.0 26985.39 25.0 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 38 HLA-E*01:01 10 FKNPAWVWLW 30662.99 26985.39 PickPocket 22.0 19.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 40 34340.59 19.0 26985.39 25.0 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-E*01:01 10 KNPAWVWLWN 20378.375 5382.48 PickPocket 11.25 0.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 41 35374.27 22.0 5382.48 0.5 None 0.5142857142857142 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-E*01:01 10 KNPAWVWLWN 20378.375 5382.48 PickPocket 11.25 0.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 41 35374.27 22.0 5382.48 0.5 None 0.5142857142857142 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 27 HLA-E*01:01 10 IMKSADVVKQ 22172.7 6978.43 PickPocket 14.5 1.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 29 37366.97 28.0 6978.43 1.0 None -0.21428571428571422 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 27 HLA-E*01:01 10 IMKSADVVKQ 22172.7 6978.43 PickPocket 14.5 1.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 29 37366.97 28.0 6978.43 1.0 None -0.21428571428571422 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 35 HLA-E*01:01 10 KQRFKNPAWV 24513.935 11355.63 PickPocket 16.3 3.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 37 37672.24 29.0 11355.63 3.6 None -0.15714285714285708 -0.15714285714285708 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 35 HLA-E*01:01 10 KQRFKNPAWV 24513.935 11355.63 PickPocket 16.3 3.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 37 37672.24 29.0 11355.63 3.6 None -0.15714285714285708 -0.15714285714285708 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 34 HLA-E*01:01 10 VKQRFKNPAW 31332.91 24747.82 PickPocket 26.0 22.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 36 37918.0 30.0 24747.82 22.0 None -1.4 -1.4 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 34 HLA-E*01:01 10 VKQRFKNPAW 31332.91 24747.82 PickPocket 26.0 22.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 36 37918.0 30.0 24747.82 22.0 None -1.4 -1.4 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 36 HLA-E*01:01 10 QRFKNPAWVW 44396.395 38792.79 NetMHC 45.5 34.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 38 38792.79 34.0 50000.0 57.0 None -0.6857142857142857 -0.15714285714285708 True False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 36 HLA-E*01:01 10 QRFKNPAWVW 44396.395 38792.79 NetMHC 45.5 34.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 38 38792.79 34.0 50000.0 57.0 None -0.6857142857142857 -0.15714285714285708 True False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-E*01:01 10 IMKSADVVNR 23794.95 8297.38 PickPocket 18.8 1.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 28 39292.52 36.0 8297.38 1.6 None -0.29999999999999993 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-E*01:01 10 IMKSADVVNR 23794.95 8297.38 PickPocket 18.8 1.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 28 39292.52 36.0 8297.38 1.6 None -0.29999999999999993 0.6000000000000002 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 719 HLA-E*01:01 10 SEETIKVYCL 38361.725 36931.66 PickPocket 39.5 39.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 3 39791.79 39.0 36931.66 40.0 9 1.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 719 HLA-E*01:01 10 SEETIKVYCL 38361.725 36931.66 PickPocket 39.5 39.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 3 39791.79 39.0 36931.66 40.0 9 1.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 720 HLA-E*01:01 10 SEETIKVYCL 38361.725 36931.66 PickPocket 39.5 39.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 3 39791.79 39.0 36931.66 40.0 9 1.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 720 HLA-E*01:01 10 SEETIKVYCL 38361.725 36931.66 PickPocket 39.5 39.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 3 39791.79 39.0 36931.66 40.0 9 1.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 723 HLA-E*01:01 10 IKVYCLQKEL 37130.955 34237.82 PickPocket 38.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 7 40024.09 40.0 34237.82 36.0 5 -0.3000000000000001 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 723 HLA-E*01:01 10 IKVYCLQKEL 37130.955 34237.82 PickPocket 38.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 7 40024.09 40.0 34237.82 36.0 5 -0.3000000000000001 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 724 HLA-E*01:01 10 IKVYCLQKEL 37130.955 34237.82 PickPocket 38.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 7 40024.09 40.0 34237.82 36.0 5 -0.3000000000000001 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 724 HLA-E*01:01 10 IKVYCLQKEL 37130.955 34237.82 PickPocket 38.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 7 40024.09 40.0 34237.82 36.0 5 -0.3000000000000001 0.9000000000000001 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 26 HLA-E*01:01 10 HIMKSADVVN 33688.33 26985.39 PickPocket 33.5 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 27 40391.27 42.0 26985.39 25.0 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 26 HLA-E*01:01 10 HIMKSADVVN 33688.33 26985.39 PickPocket 33.5 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 27 40391.27 42.0 26985.39 25.0 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 720 HLA-E*01:01 10 EETIKVYCLQ 45324.525 40649.05 NetMHC 50.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 4 40649.05 44.0 50000.0 57.0 8 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 720 HLA-E*01:01 10 EETIKVYCLQ 45324.525 40649.05 NetMHC 50.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 4 40649.05 44.0 50000.0 57.0 8 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 721 HLA-E*01:01 10 EETIKVYCLQ 45324.525 40649.05 NetMHC 50.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 4 40649.05 44.0 50000.0 57.0 8 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 721 HLA-E*01:01 10 EETIKVYCLQ 45324.525 40649.05 NetMHC 50.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 4 40649.05 44.0 50000.0 57.0 8 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 757 HLA-E*01:01 10 LKKKSEEKEL 34601.755 27575.71 PickPocket 38.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 11 41627.8 51.0 27575.71 26.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 757 HLA-E*01:01 10 LKKKSEEKEL 34601.755 27575.71 PickPocket 38.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 11 41627.8 51.0 27575.71 26.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 758 HLA-E*01:01 10 LKKKSEEKEL 34601.755 27575.71 PickPocket 38.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 11 41627.8 51.0 27575.71 26.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 758 HLA-E*01:01 10 LKKKSEEKEL 34601.755 27575.71 PickPocket 38.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 11 41627.8 51.0 27575.71 26.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 717 HLA-E*01:01 10 QVSEETIKVY 46047.84 42095.68 NetMHC 55.5 54.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 1 42095.68 54.0 50000.0 57.0 None -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 717 HLA-E*01:01 10 QVSEETIKVY 46047.84 42095.68 NetMHC 55.5 54.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 1 42095.68 54.0 50000.0 57.0 None -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 718 HLA-E*01:01 10 QVSEETIKVY 46047.84 42095.68 NetMHC 55.5 54.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 1 42095.68 54.0 50000.0 57.0 None -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 718 HLA-E*01:01 10 QVSEETIKVY 46047.84 42095.68 NetMHC 55.5 54.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 1 42095.68 54.0 50000.0 57.0 None -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 35 HLA-E*01:01 10 KVKCKLTQSF 38688.63 34986.78 PickPocket 47.0 37.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 26 42390.48 57.0 34986.78 37.0 4 0.028571428571428532 0.028571428571428532 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 35 HLA-E*01:01 10 KVKCKLTQSF 38688.63 34986.78 PickPocket 47.0 37.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 26 42390.48 57.0 34986.78 37.0 4 0.028571428571428532 0.028571428571428532 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-E*01:01 10 MKSADVVKVK 34671.555 26694.99 PickPocket 42.0 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 19 42648.12 59.0 26694.99 25.0 None 0.4428571428571429 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-E*01:01 10 MKSADVVKVK 34671.555 26694.99 PickPocket 42.0 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 19 42648.12 59.0 26694.99 25.0 None 0.4428571428571429 0.8857142857142859 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 758 HLA-E*01:01 10 KKKSEEKELK 40893.36 38984.65 PickPocket 51.5 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 12 42802.07 60.0 38984.65 43.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 758 HLA-E*01:01 10 KKKSEEKELK 40893.36 38984.65 PickPocket 51.5 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 12 42802.07 60.0 38984.65 43.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 759 HLA-E*01:01 10 KKKSEEKELK 40893.36 38984.65 PickPocket 51.5 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 12 42802.07 60.0 38984.65 43.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 759 HLA-E*01:01 10 KKKSEEKELK 40893.36 38984.65 PickPocket 51.5 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 12 42802.07 60.0 38984.65 43.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 33 HLA-E*01:01 10 VVKVKCKLTQ 33981.22 25017.04 PickPocket 42.0 22.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 24 42945.4 62.0 25017.04 22.0 6 -0.21428571428571427 0.4857142857142856 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 33 HLA-E*01:01 10 VVKVKCKLTQ 33981.22 25017.04 PickPocket 42.0 22.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 24 42945.4 62.0 25017.04 22.0 6 -0.21428571428571427 0.4857142857142856 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 32 HLA-E*01:01 10 DVVKVKCKLT 46790.065 43580.13 NetMHC 62.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 23 43580.13 68.0 50000.0 57.0 7 -0.27142857142857146 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 32 HLA-E*01:01 10 DVVKVKCKLT 46790.065 43580.13 NetMHC 62.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 23 43580.13 68.0 50000.0 57.0 7 -0.27142857142857146 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 34 HLA-E*01:01 10 VKVKCKLTQS 46826.17 43652.34 NetMHC 62.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 25 43652.34 68.0 50000.0 57.0 5 -0.9285714285714286 0.42857142857142855 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 34 HLA-E*01:01 10 VKVKCKLTQS 46826.17 43652.34 NetMHC 62.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 25 43652.34 68.0 50000.0 57.0 5 -0.9285714285714286 0.42857142857142855 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 31 HLA-E*01:01 10 ADVVKVKCKL 35783.375 27875.69 PickPocket 48.0 27.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 22 43691.06 69.0 27875.69 27.0 8 0.42857142857142855 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 31 HLA-E*01:01 10 ADVVKVKCKL 35783.375 27875.69 PickPocket 48.0 27.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 22 43691.06 69.0 27875.69 27.0 8 0.42857142857142855 0.542857142857143 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 759 HLA-E*01:01 10 KKSEEKELKI 30601.735 17505.31 PickPocket 40.5 12.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 13 43698.16 69.0 17505.31 12.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 759 HLA-E*01:01 10 KKSEEKELKI 30601.735 17505.31 PickPocket 40.5 12.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 13 43698.16 69.0 17505.31 12.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 760 HLA-E*01:01 10 KKSEEKELKI 30601.735 17505.31 PickPocket 40.5 12.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 13 43698.16 69.0 17505.31 12.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 760 HLA-E*01:01 10 KKSEEKELKI 30601.735 17505.31 PickPocket 40.5 12.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 13 43698.16 69.0 17505.31 12.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-E*01:01 10 KSEEKELKIK 31928.055 19932.31 PickPocket 43.0 15.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 14 43923.8 71.0 19932.31 15.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-E*01:01 10 KSEEKELKIK 31928.055 19932.31 PickPocket 43.0 15.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 14 43923.8 71.0 19932.31 15.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-E*01:01 10 KSEEKELKIK 31928.055 19932.31 PickPocket 43.0 15.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 14 43923.8 71.0 19932.31 15.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-E*01:01 10 KSEEKELKIK 31928.055 19932.31 PickPocket 43.0 15.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 14 43923.8 71.0 19932.31 15.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 724 HLA-E*01:01 10 KVYCLQKELK 47151.625 44303.25 NetMHC 66.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 8 44303.25 75.0 50000.0 57.0 4 -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 724 HLA-E*01:01 10 KVYCLQKELK 47151.625 44303.25 NetMHC 66.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 8 44303.25 75.0 50000.0 57.0 4 -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-E*01:01 10 KVYCLQKELK 47151.625 44303.25 NetMHC 66.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 8 44303.25 75.0 50000.0 57.0 4 -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-E*01:01 10 KVYCLQKELK 47151.625 44303.25 NetMHC 66.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 8 44303.25 75.0 50000.0 57.0 4 -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 756 HLA-E*01:01 10 QLKKKSEEKE 37190.42 30068.96 PickPocket 52.5 30.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 10 44311.88 75.0 30068.96 30.0 None -3.2857142857142856 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 756 HLA-E*01:01 10 QLKKKSEEKE 37190.42 30068.96 PickPocket 52.5 30.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 10 44311.88 75.0 30068.96 30.0 None -3.2857142857142856 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 757 HLA-E*01:01 10 QLKKKSEEKE 37190.42 30068.96 PickPocket 52.5 30.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 10 44311.88 75.0 30068.96 30.0 None -3.2857142857142856 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 757 HLA-E*01:01 10 QLKKKSEEKE 37190.42 30068.96 PickPocket 52.5 30.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 10 44311.88 75.0 30068.96 30.0 None -3.2857142857142856 -2.242857142857143 True False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 33 HLA-E*01:01 10 VVKQRFKNPA 47279.25 44558.5 NetMHC 67.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 35 44558.5 78.0 50000.0 57.0 None -1.7714285714285711 -0.6571428571428571 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 33 HLA-E*01:01 10 VVKQRFKNPA 47279.25 44558.5 NetMHC 67.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 35 44558.5 78.0 50000.0 57.0 None -1.7714285714285711 -0.6571428571428571 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 755 HLA-E*01:01 10 KQLKKKSEEK 36104.265 27575.71 PickPocket 52.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 9 44632.82 79.0 27575.71 26.0 None -3.3428571428571425 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 755 HLA-E*01:01 10 KQLKKKSEEK 36104.265 27575.71 PickPocket 52.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 9 44632.82 79.0 27575.71 26.0 None -3.3428571428571425 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 756 HLA-E*01:01 10 KQLKKKSEEK 36104.265 27575.71 PickPocket 52.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 9 44632.82 79.0 27575.71 26.0 None -3.3428571428571425 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 756 HLA-E*01:01 10 KQLKKKSEEK 36104.265 27575.71 PickPocket 52.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 9 44632.82 79.0 27575.71 26.0 None -3.3428571428571425 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-E*01:01 10 VSEETIKVYC 41639.805 38565.12 PickPocket 61.0 42.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 2 44714.49 80.0 38565.12 42.0 10 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-E*01:01 10 VSEETIKVYC 41639.805 38565.12 PickPocket 61.0 42.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 2 44714.49 80.0 38565.12 42.0 10 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-E*01:01 10 VSEETIKVYC 41639.805 38565.12 PickPocket 61.0 42.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 2 44714.49 80.0 38565.12 42.0 10 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-E*01:01 10 VSEETIKVYC 41639.805 38565.12 PickPocket 61.0 42.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 2 44714.49 80.0 38565.12 42.0 10 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 28 HLA-E*01:01 10 MKSADVVKQR 36390.37 27875.69 PickPocket 54.5 27.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 30 44905.05 82.0 27875.69 27.0 None -0.7428571428571428 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 28 HLA-E*01:01 10 MKSADVVKQR 36390.37 27875.69 PickPocket 54.5 27.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 30 44905.05 82.0 27875.69 27.0 None -0.7428571428571428 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 32 HLA-E*01:01 10 DVVKQRFKNP 47525.52 45051.04 NetMHC 70.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 34 45051.04 84.0 50000.0 57.0 None -2.585714285714286 -0.6 False False True 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 32 HLA-E*01:01 10 DVVKQRFKNP 47525.52 45051.04 NetMHC 70.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 34 45051.04 84.0 50000.0 57.0 None -2.585714285714286 -0.6 False False True 0 False 1 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 722 HLA-E*01:01 10 TIKVYCLQKE 39770.14 33869.37 PickPocket 62.5 35.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 6 45670.91 90.0 33869.37 35.0 6 -0.24285714285714294 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 722 HLA-E*01:01 10 TIKVYCLQKE 39770.14 33869.37 PickPocket 62.5 35.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 6 45670.91 90.0 33869.37 35.0 6 -0.24285714285714294 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 723 HLA-E*01:01 10 TIKVYCLQKE 39770.14 33869.37 PickPocket 62.5 35.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 6 45670.91 90.0 33869.37 35.0 6 -0.24285714285714294 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 723 HLA-E*01:01 10 TIKVYCLQKE 39770.14 33869.37 PickPocket 62.5 35.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 6 45670.91 90.0 33869.37 35.0 6 -0.24285714285714294 1.3 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 29 HLA-E*01:01 10 KSADVVKQRF 35723.105 25564.3 PickPocket 57.5 23.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 31 45881.91 92.0 25564.3 23.0 None -0.6 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 29 HLA-E*01:01 10 KSADVVKQRF 35723.105 25564.3 PickPocket 57.5 23.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 31 45881.91 92.0 25564.3 23.0 None -0.6 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 31 HLA-E*01:01 10 ADVVKQRFKN 36213.66 26407.71 PickPocket 59.5 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 33 46019.61 94.0 26407.71 25.0 None -1.757142857142857 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 31 HLA-E*01:01 10 ADVVKQRFKN 36213.66 26407.71 PickPocket 59.5 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 33 46019.61 94.0 26407.71 25.0 None -1.757142857142857 -0.6 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 721 HLA-E*01:01 10 ETIKVYCLQK 48024.755 46049.51 NetMHC 75.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 5 46049.51 94.0 50000.0 57.0 7 -0.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 721 HLA-E*01:01 10 ETIKVYCLQK 48024.755 46049.51 NetMHC 75.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 5 46049.51 94.0 50000.0 57.0 7 -0.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 722 HLA-E*01:01 10 ETIKVYCLQK 48024.755 46049.51 NetMHC 75.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 5 46049.51 94.0 50000.0 57.0 7 -0.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 722 HLA-E*01:01 10 ETIKVYCLQK 48024.755 46049.51 NetMHC 75.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 5 46049.51 94.0 50000.0 57.0 7 -0.3 1.3 True False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 29 HLA-E*01:01 10 KSADVVKVKC 36980.625 27575.71 PickPocket 61.5 26.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 20 46385.54 97.0 27575.71 26.0 10 0.542857142857143 0.8857142857142859 False True False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 29 HLA-E*01:01 10 KSADVVKVKC 36980.625 27575.71 PickPocket 61.5 26.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 20 46385.54 97.0 27575.71 26.0 10 0.542857142857143 0.8857142857142859 False True False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 30 HLA-E*01:01 10 SADVVKQRFK 48213.105 46426.21 NetMHC 77.0 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 32 46426.21 97.0 50000.0 57.0 None -0.6571428571428571 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 30 HLA-E*01:01 10 SADVVKQRFK 48213.105 46426.21 NetMHC 77.0 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 32 46426.21 97.0 50000.0 57.0 None -0.6571428571428571 -0.21428571428571422 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 761 HLA-E*01:01 10 SEEKELKIKN 48342.81 46685.62 NetMHC 78.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 15 46685.62 99.0 50000.0 57.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 761 HLA-E*01:01 10 SEEKELKIKN 48342.81 46685.62 NetMHC 78.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 15 46685.62 99.0 50000.0 57.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 762 HLA-E*01:01 10 SEEKELKIKN 48342.81 46685.62 NetMHC 78.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 15 46685.62 99.0 50000.0 57.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 762 HLA-E*01:01 10 SEEKELKIKN 48342.81 46685.62 NetMHC 78.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 15 46685.62 99.0 50000.0 57.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 30 HLA-E*01:01 10 SADVVKVKCK 48443.8 46887.6 NetMHC 78.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 21 46887.6 100.0 50000.0 57.0 9 0.4857142857142856 0.8857142857142859 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 30 HLA-E*01:01 10 SADVVKVKCK 48443.8 46887.6 NetMHC 78.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 21 46887.6 100.0 50000.0 57.0 9 0.4857142857142856 0.8857142857142859 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 762 HLA-E*01:01 10 EEKELKIKNH 48560.78 47121.56 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 16 47121.56 100.0 50000.0 57.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 762 HLA-E*01:01 10 EEKELKIKNH 48560.78 47121.56 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 16 47121.56 100.0 50000.0 57.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 763 HLA-E*01:01 10 EEKELKIKNH 48560.78 47121.56 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 16 47121.56 100.0 50000.0 57.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 763 HLA-E*01:01 10 EEKELKIKNH 48560.78 47121.56 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 16 47121.56 100.0 50000.0 57.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 763 HLA-E*01:01 10 EKELKIKNHS 48597.26 47194.52 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 17 47194.52 100.0 50000.0 57.0 None -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 763 HLA-E*01:01 10 EKELKIKNHS 48597.26 47194.52 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 17 47194.52 100.0 50000.0 57.0 None -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 764 HLA-E*01:01 10 EKELKIKNHS 48597.26 47194.52 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 17 47194.52 100.0 50000.0 57.0 None -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 764 HLA-E*01:01 10 EKELKIKNHS 48597.26 47194.52 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 17 47194.52 100.0 50000.0 57.0 None -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-G*01:09 10 RFKNPAWVWL 5620.54 5620.54 PickPocket 1.8 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 39 NA NA 5620.54 1.8 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-G*01:09 10 RFKNPAWVWL 5620.54 5620.54 PickPocket 1.8 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 39 NA NA 5620.54 1.8 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-G*01:09 10 KNPAWVWLWN 7208.66 7208.66 PickPocket 3.0 3.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 41 NA NA 7208.66 3.0 None 0.5142857142857142 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-G*01:09 10 KNPAWVWLWN 7208.66 7208.66 PickPocket 3.0 3.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 41 NA NA 7208.66 3.0 None 0.5142857142857142 0.7857142857142857 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 724 HLA-G*01:09 10 KVYCLQKELK 7860.43 7860.43 PickPocket 3.5 3.5 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 8 NA NA 7860.43 3.5 4 -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 724 HLA-G*01:09 10 KVYCLQKELK 7860.43 7860.43 PickPocket 3.5 3.5 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 8 NA NA 7860.43 3.5 4 -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-G*01:09 10 KVYCLQKELK 7860.43 7860.43 PickPocket 3.5 3.5 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 8 NA NA 7860.43 3.5 4 -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-G*01:09 10 KVYCLQKELK 7860.43 7860.43 PickPocket 3.5 3.5 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 8 NA NA 7860.43 3.5 4 -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 35 HLA-G*01:09 10 KQRFKNPAWV 11730.27 11730.27 PickPocket 6.7 6.7 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 37 NA NA 11730.27 6.7 None -0.15714285714285708 -0.15714285714285708 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 35 HLA-G*01:09 10 KQRFKNPAWV 11730.27 11730.27 PickPocket 6.7 6.7 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 37 NA NA 11730.27 6.7 None -0.15714285714285708 -0.15714285714285708 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 26 HLA-G*01:09 10 HIMKSADVVN 11857.88 11857.88 PickPocket 6.8 6.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 27 NA NA 11857.88 6.8 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 26 HLA-G*01:09 10 HIMKSADVVN 11857.88 11857.88 PickPocket 6.8 6.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 27 NA NA 11857.88 6.8 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 35 HLA-G*01:09 10 KVKCKLTQSF 19717.81 19717.81 PickPocket 16.0 16.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 26 NA NA 19717.81 16.0 4 0.028571428571428532 0.028571428571428532 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 35 HLA-G*01:09 10 KVKCKLTQSF 19717.81 19717.81 PickPocket 16.0 16.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 26 NA NA 19717.81 16.0 4 0.028571428571428532 0.028571428571428532 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 719 HLA-G*01:09 10 SEETIKVYCL 29108.61 29108.61 PickPocket 25.0 25.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 3 NA NA 29108.61 25.0 9 1.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 719 HLA-G*01:09 10 SEETIKVYCL 29108.61 29108.61 PickPocket 25.0 25.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 3 NA NA 29108.61 25.0 9 1.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 720 HLA-G*01:09 10 SEETIKVYCL 29108.61 29108.61 PickPocket 25.0 25.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 3 NA NA 29108.61 25.0 9 1.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 720 HLA-G*01:09 10 SEETIKVYCL 29108.61 29108.61 PickPocket 25.0 25.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 3 NA NA 29108.61 25.0 9 1.3 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-G*01:09 10 VSEETIKVYC 32787.64 32787.64 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 2 NA NA 32787.64 29.0 10 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-G*01:09 10 VSEETIKVYC 32787.64 32787.64 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 2 NA NA 32787.64 29.0 10 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-G*01:09 10 VSEETIKVYC 32787.64 32787.64 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 2 NA NA 32787.64 29.0 10 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-G*01:09 10 VSEETIKVYC 32787.64 32787.64 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 2 NA NA 32787.64 29.0 10 0.2571428571428572 0.2571428571428572 False True False 1 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 755 HLA-G*01:09 10 KQLKKKSEEK 33504.88 33504.88 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 9 NA NA 33504.88 29.0 None -3.3428571428571425 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 755 HLA-G*01:09 10 KQLKKKSEEK 33504.88 33504.88 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 9 NA NA 33504.88 29.0 None -3.3428571428571425 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 756 HLA-G*01:09 10 KQLKKKSEEK 33504.88 33504.88 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 9 NA NA 33504.88 29.0 None -3.3428571428571425 -2.242857142857143 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 756 HLA-G*01:09 10 KQLKKKSEEK 33504.88 33504.88 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 9 NA NA 33504.88 29.0 None -3.3428571428571425 -2.242857142857143 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 27 HLA-G*01:09 10 IMKSADVVKV 39408.75 39408.75 PickPocket 35.0 35.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 18 NA NA 39408.75 35.0 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 27 HLA-G*01:09 10 IMKSADVVKV 39408.75 39408.75 PickPocket 35.0 35.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 18 NA NA 39408.75 35.0 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-G*01:09 10 KSEEKELKIK 41599.44 41599.44 PickPocket 36.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 14 NA NA 41599.44 36.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-G*01:09 10 KSEEKELKIK 41599.44 41599.44 PickPocket 36.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 14 NA NA 41599.44 36.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-G*01:09 10 KSEEKELKIK 41599.44 41599.44 PickPocket 36.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 14 NA NA 41599.44 36.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-G*01:09 10 KSEEKELKIK 41599.44 41599.44 PickPocket 36.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 14 NA NA 41599.44 36.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 29 HLA-G*01:09 10 KSADVVKQRF 44872.5 44872.5 PickPocket 39.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 31 NA NA 44872.5 39.0 None -0.6 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 29 HLA-G*01:09 10 KSADVVKQRF 44872.5 44872.5 PickPocket 39.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 31 NA NA 44872.5 39.0 None -0.6 -0.21428571428571422 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 717 HLA-G*01:09 10 QVSEETIKVY 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 50000.0 43.0 None -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 717 HLA-G*01:09 10 QVSEETIKVY 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 50000.0 43.0 None -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 718 HLA-G*01:09 10 QVSEETIKVY 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 50000.0 43.0 None -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 718 HLA-G*01:09 10 QVSEETIKVY 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 50000.0 43.0 None -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 720 HLA-G*01:09 10 EETIKVYCLQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 4 NA NA 50000.0 43.0 8 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 720 HLA-G*01:09 10 EETIKVYCLQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 4 NA NA 50000.0 43.0 8 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 721 HLA-G*01:09 10 EETIKVYCLQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 4 NA NA 50000.0 43.0 8 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 721 HLA-G*01:09 10 EETIKVYCLQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 4 NA NA 50000.0 43.0 8 0.9000000000000001 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 721 HLA-G*01:09 10 ETIKVYCLQK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 5 NA NA 50000.0 43.0 7 -0.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 721 HLA-G*01:09 10 ETIKVYCLQK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 5 NA NA 50000.0 43.0 7 -0.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 722 HLA-G*01:09 10 ETIKVYCLQK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 5 NA NA 50000.0 43.0 7 -0.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 722 HLA-G*01:09 10 ETIKVYCLQK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 5 NA NA 50000.0 43.0 7 -0.3 1.3 True False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 722 HLA-G*01:09 10 TIKVYCLQKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 6 NA NA 50000.0 43.0 6 -0.24285714285714294 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 722 HLA-G*01:09 10 TIKVYCLQKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 6 NA NA 50000.0 43.0 6 -0.24285714285714294 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 723 HLA-G*01:09 10 TIKVYCLQKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 6 NA NA 50000.0 43.0 6 -0.24285714285714294 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 723 HLA-G*01:09 10 TIKVYCLQKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 6 NA NA 50000.0 43.0 6 -0.24285714285714294 1.3 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 723 HLA-G*01:09 10 IKVYCLQKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 7 NA NA 50000.0 43.0 5 -0.3000000000000001 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 723 HLA-G*01:09 10 IKVYCLQKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 7 NA NA 50000.0 43.0 5 -0.3000000000000001 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 724 HLA-G*01:09 10 IKVYCLQKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 7 NA NA 50000.0 43.0 5 -0.3000000000000001 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 724 HLA-G*01:09 10 IKVYCLQKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 7 NA NA 50000.0 43.0 5 -0.3000000000000001 0.9000000000000001 False False False 1 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 756 HLA-G*01:09 10 QLKKKSEEKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 10 NA NA 50000.0 43.0 None -3.2857142857142856 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 756 HLA-G*01:09 10 QLKKKSEEKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 10 NA NA 50000.0 43.0 None -3.2857142857142856 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 757 HLA-G*01:09 10 QLKKKSEEKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 10 NA NA 50000.0 43.0 None -3.2857142857142856 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 757 HLA-G*01:09 10 QLKKKSEEKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 10 NA NA 50000.0 43.0 None -3.2857142857142856 -2.242857142857143 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 757 HLA-G*01:09 10 LKKKSEEKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 11 NA NA 50000.0 43.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 757 HLA-G*01:09 10 LKKKSEEKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 11 NA NA 50000.0 43.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 758 HLA-G*01:09 10 LKKKSEEKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 11 NA NA 50000.0 43.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 758 HLA-G*01:09 10 LKKKSEEKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 11 NA NA 50000.0 43.0 None -2.185714285714286 -2.185714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 758 HLA-G*01:09 10 KKKSEEKELK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 50000.0 43.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 758 HLA-G*01:09 10 KKKSEEKELK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 50000.0 43.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 759 HLA-G*01:09 10 KKKSEEKELK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 50000.0 43.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 759 HLA-G*01:09 10 KKKSEEKELK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 50000.0 43.0 None -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 759 HLA-G*01:09 10 KKSEEKELKI 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 13 NA NA 50000.0 43.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 759 HLA-G*01:09 10 KKSEEKELKI 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 13 NA NA 50000.0 43.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 760 HLA-G*01:09 10 KKSEEKELKI 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 13 NA NA 50000.0 43.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 760 HLA-G*01:09 10 KKSEEKELKI 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 13 NA NA 50000.0 43.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 761 HLA-G*01:09 10 SEEKELKIKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 15 NA NA 50000.0 43.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 761 HLA-G*01:09 10 SEEKELKIKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 15 NA NA 50000.0 43.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 762 HLA-G*01:09 10 SEEKELKIKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 15 NA NA 50000.0 43.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 762 HLA-G*01:09 10 SEEKELKIKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 15 NA NA 50000.0 43.0 None -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 762 HLA-G*01:09 10 EEKELKIKNH 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 16 NA NA 50000.0 43.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 762 HLA-G*01:09 10 EEKELKIKNH 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 16 NA NA 50000.0 43.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 763 HLA-G*01:09 10 EEKELKIKNH 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 16 NA NA 50000.0 43.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 763 HLA-G*01:09 10 EEKELKIKNH 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 16 NA NA 50000.0 43.0 None -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 763 HLA-G*01:09 10 EKELKIKNHS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 17 NA NA 50000.0 43.0 None -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 763 HLA-G*01:09 10 EKELKIKNHS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 17 NA NA 50000.0 43.0 None -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 764 HLA-G*01:09 10 EKELKIKNHS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 17 NA NA 50000.0 43.0 None -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 764 HLA-G*01:09 10 EKELKIKNHS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 17 NA NA 50000.0 43.0 None -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-G*01:09 10 MKSADVVKVK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 19 NA NA 50000.0 43.0 None 0.4428571428571429 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-G*01:09 10 MKSADVVKVK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 19 NA NA 50000.0 43.0 None 0.4428571428571429 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 29 HLA-G*01:09 10 KSADVVKVKC 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 20 NA NA 50000.0 43.0 10 0.542857142857143 0.8857142857142859 False True False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 29 HLA-G*01:09 10 KSADVVKVKC 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 20 NA NA 50000.0 43.0 10 0.542857142857143 0.8857142857142859 False True False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 30 HLA-G*01:09 10 SADVVKVKCK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 21 NA NA 50000.0 43.0 9 0.4857142857142856 0.8857142857142859 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 30 HLA-G*01:09 10 SADVVKVKCK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 21 NA NA 50000.0 43.0 9 0.4857142857142856 0.8857142857142859 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 31 HLA-G*01:09 10 ADVVKVKCKL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 22 NA NA 50000.0 43.0 8 0.42857142857142855 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 31 HLA-G*01:09 10 ADVVKVKCKL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 22 NA NA 50000.0 43.0 8 0.42857142857142855 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 32 HLA-G*01:09 10 DVVKVKCKLT 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 23 NA NA 50000.0 43.0 7 -0.27142857142857146 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 32 HLA-G*01:09 10 DVVKVKCKLT 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 23 NA NA 50000.0 43.0 7 -0.27142857142857146 0.542857142857143 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 33 HLA-G*01:09 10 VVKVKCKLTQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 24 NA NA 50000.0 43.0 6 -0.21428571428571427 0.4857142857142856 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 33 HLA-G*01:09 10 VVKVKCKLTQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 24 NA NA 50000.0 43.0 6 -0.21428571428571427 0.4857142857142856 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 34 HLA-G*01:09 10 VKVKCKLTQS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 25 NA NA 50000.0 43.0 5 -0.9285714285714286 0.42857142857142855 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 34 HLA-G*01:09 10 VKVKCKLTQS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 25 NA NA 50000.0 43.0 5 -0.9285714285714286 0.42857142857142855 False False False 1 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-G*01:09 10 IMKSADVVNR 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 28 NA NA 50000.0 43.0 None -0.29999999999999993 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-G*01:09 10 IMKSADVVNR 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 28 NA NA 50000.0 43.0 None -0.29999999999999993 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 27 HLA-G*01:09 10 IMKSADVVKQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 29 NA NA 50000.0 43.0 None -0.21428571428571422 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 27 HLA-G*01:09 10 IMKSADVVKQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 29 NA NA 50000.0 43.0 None -0.21428571428571422 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 28 HLA-G*01:09 10 MKSADVVKQR 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 30 NA NA 50000.0 43.0 None -0.7428571428571428 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 28 HLA-G*01:09 10 MKSADVVKQR 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 30 NA NA 50000.0 43.0 None -0.7428571428571428 0.5571428571428572 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 30 HLA-G*01:09 10 SADVVKQRFK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 32 NA NA 50000.0 43.0 None -0.6571428571428571 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 30 HLA-G*01:09 10 SADVVKQRFK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 32 NA NA 50000.0 43.0 None -0.6571428571428571 -0.21428571428571422 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 31 HLA-G*01:09 10 ADVVKQRFKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 33 NA NA 50000.0 43.0 None -1.757142857142857 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 31 HLA-G*01:09 10 ADVVKQRFKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 33 NA NA 50000.0 43.0 None -1.757142857142857 -0.6 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 32 HLA-G*01:09 10 DVVKQRFKNP 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 34 NA NA 50000.0 43.0 None -2.585714285714286 -0.6 False False True 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 32 HLA-G*01:09 10 DVVKQRFKNP 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 34 NA NA 50000.0 43.0 None -2.585714285714286 -0.6 False False True 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 33 HLA-G*01:09 10 VVKQRFKNPA 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 35 NA NA 50000.0 43.0 None -1.7714285714285711 -0.6571428571428571 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 33 HLA-G*01:09 10 VVKQRFKNPA 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 35 NA NA 50000.0 43.0 None -1.7714285714285711 -0.6571428571428571 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 34 HLA-G*01:09 10 VKQRFKNPAW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 36 NA NA 50000.0 43.0 None -1.4 -1.4 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 34 HLA-G*01:09 10 VKQRFKNPAW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 36 NA NA 50000.0 43.0 None -1.4 -1.4 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 36 HLA-G*01:09 10 QRFKNPAWVW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 38 NA NA 50000.0 43.0 None -0.6857142857142857 -0.15714285714285708 True False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 36 HLA-G*01:09 10 QRFKNPAWVW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 38 NA NA 50000.0 43.0 None -0.6857142857142857 -0.15714285714285708 True False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 38 HLA-G*01:09 10 FKNPAWVWLW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 40 NA NA 50000.0 43.0 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 38 HLA-G*01:09 10 FKNPAWVWLW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 40 NA NA 50000.0 43.0 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +Chromosome Start Stop Reference Variant Junction Junction Start Junction Stop Junction Score Junction Anchor Transcript Transcript Support Level Canonical MANE Select Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Amino Acid Change Gene Name HGVSc HGVSp WT Protein Length ALT Protein Length Frameshift Event Protein Position HLA Allele Peptide Length Epitope Seq Median IC50 Score Best IC50 Score Best IC50 Score Method Median Percentile Best Percentile Best Percentile Method Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Index Fasta Key NetMHC IC50 Score NetMHC Percentile PickPocket IC50 Score PickPocket Percentile Problematic Positions Gene of Interest cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-E*01:01 10 RFKNPAWVWL 20099.255 12790.86 PickPocket 5.9 4.9 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 27407.65 6.9 12790.86 4.9 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-E*01:01 10 RFKNPAWVWL 20099.255 12790.86 PickPocket 5.9 4.9 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 27407.65 6.9 12790.86 4.9 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 27 HLA-E*01:01 10 IMKSADVVKV 19498.205 7692.16 PickPocket 7.2 1.4 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 31304.25 13.0 7692.16 1.4 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 27 HLA-E*01:01 10 IMKSADVVKV 19498.205 7692.16 PickPocket 7.2 1.4 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 31304.25 13.0 7692.16 1.4 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 38 HLA-E*01:01 10 FKNPAWVWLW 30662.99 26985.39 PickPocket 22.0 19.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 40 34340.59 19.0 26985.39 25.0 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 38 HLA-E*01:01 10 FKNPAWVWLW 30662.99 26985.39 PickPocket 22.0 19.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 40 34340.59 19.0 26985.39 25.0 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-E*01:01 10 KNPAWVWLWN 20378.375 5382.48 PickPocket 11.25 0.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 41 35374.27 22.0 5382.48 0.5 None False 0.5142857142857142 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-E*01:01 10 KNPAWVWLWN 20378.375 5382.48 PickPocket 11.25 0.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 41 35374.27 22.0 5382.48 0.5 None False 0.5142857142857142 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 27 HLA-E*01:01 10 IMKSADVVKQ 22172.7 6978.43 PickPocket 14.5 1.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 29 37366.97 28.0 6978.43 1.0 None False -0.21428571428571422 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 27 HLA-E*01:01 10 IMKSADVVKQ 22172.7 6978.43 PickPocket 14.5 1.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 29 37366.97 28.0 6978.43 1.0 None False -0.21428571428571422 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 35 HLA-E*01:01 10 KQRFKNPAWV 24513.935 11355.63 PickPocket 16.3 3.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 37 37672.24 29.0 11355.63 3.6 None False -0.15714285714285708 -0.15714285714285708 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 35 HLA-E*01:01 10 KQRFKNPAWV 24513.935 11355.63 PickPocket 16.3 3.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 37 37672.24 29.0 11355.63 3.6 None False -0.15714285714285708 -0.15714285714285708 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 34 HLA-E*01:01 10 VKQRFKNPAW 31332.91 24747.82 PickPocket 26.0 22.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 36 37918.0 30.0 24747.82 22.0 None False -1.4 -1.4 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 34 HLA-E*01:01 10 VKQRFKNPAW 31332.91 24747.82 PickPocket 26.0 22.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 36 37918.0 30.0 24747.82 22.0 None False -1.4 -1.4 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 36 HLA-E*01:01 10 QRFKNPAWVW 44396.395 38792.79 NetMHC 45.5 34.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 38792.79 34.0 50000.0 57.0 None False -0.6857142857142857 -0.15714285714285708 True False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 36 HLA-E*01:01 10 QRFKNPAWVW 44396.395 38792.79 NetMHC 45.5 34.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 38792.79 34.0 50000.0 57.0 None False -0.6857142857142857 -0.15714285714285708 True False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-E*01:01 10 IMKSADVVNR 23794.95 8297.38 PickPocket 18.8 1.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 28 39292.52 36.0 8297.38 1.6 None False -0.29999999999999993 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-E*01:01 10 IMKSADVVNR 23794.95 8297.38 PickPocket 18.8 1.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 28 39292.52 36.0 8297.38 1.6 None False -0.29999999999999993 0.6000000000000002 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 719 HLA-E*01:01 10 SEETIKVYCL 38361.725 36931.66 PickPocket 39.5 39.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 39791.79 39.0 36931.66 40.0 9 False 1.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 719 HLA-E*01:01 10 SEETIKVYCL 38361.725 36931.66 PickPocket 39.5 39.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 39791.79 39.0 36931.66 40.0 9 False 1.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 720 HLA-E*01:01 10 SEETIKVYCL 38361.725 36931.66 PickPocket 39.5 39.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 39791.79 39.0 36931.66 40.0 9 False 1.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 720 HLA-E*01:01 10 SEETIKVYCL 38361.725 36931.66 PickPocket 39.5 39.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 39791.79 39.0 36931.66 40.0 9 False 1.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 723 HLA-E*01:01 10 IKVYCLQKEL 37130.955 34237.82 PickPocket 38.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 40024.09 40.0 34237.82 36.0 5 False -0.3000000000000001 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 723 HLA-E*01:01 10 IKVYCLQKEL 37130.955 34237.82 PickPocket 38.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 40024.09 40.0 34237.82 36.0 5 False -0.3000000000000001 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 724 HLA-E*01:01 10 IKVYCLQKEL 37130.955 34237.82 PickPocket 38.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 40024.09 40.0 34237.82 36.0 5 False -0.3000000000000001 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 724 HLA-E*01:01 10 IKVYCLQKEL 37130.955 34237.82 PickPocket 38.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 40024.09 40.0 34237.82 36.0 5 False -0.3000000000000001 0.9000000000000001 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 26 HLA-E*01:01 10 HIMKSADVVN 33688.33 26985.39 PickPocket 33.5 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 27 40391.27 42.0 26985.39 25.0 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 26 HLA-E*01:01 10 HIMKSADVVN 33688.33 26985.39 PickPocket 33.5 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 27 40391.27 42.0 26985.39 25.0 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 720 HLA-E*01:01 10 EETIKVYCLQ 45324.525 40649.05 NetMHC 50.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 40649.05 44.0 50000.0 57.0 8 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 720 HLA-E*01:01 10 EETIKVYCLQ 45324.525 40649.05 NetMHC 50.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 40649.05 44.0 50000.0 57.0 8 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 721 HLA-E*01:01 10 EETIKVYCLQ 45324.525 40649.05 NetMHC 50.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 40649.05 44.0 50000.0 57.0 8 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 721 HLA-E*01:01 10 EETIKVYCLQ 45324.525 40649.05 NetMHC 50.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 40649.05 44.0 50000.0 57.0 8 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 757 HLA-E*01:01 10 LKKKSEEKEL 34601.755 27575.71 PickPocket 38.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 41627.8 51.0 27575.71 26.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 757 HLA-E*01:01 10 LKKKSEEKEL 34601.755 27575.71 PickPocket 38.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 41627.8 51.0 27575.71 26.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 758 HLA-E*01:01 10 LKKKSEEKEL 34601.755 27575.71 PickPocket 38.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 41627.8 51.0 27575.71 26.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 758 HLA-E*01:01 10 LKKKSEEKEL 34601.755 27575.71 PickPocket 38.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 41627.8 51.0 27575.71 26.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 717 HLA-E*01:01 10 QVSEETIKVY 46047.84 42095.68 NetMHC 55.5 54.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 42095.68 54.0 50000.0 57.0 None False -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 717 HLA-E*01:01 10 QVSEETIKVY 46047.84 42095.68 NetMHC 55.5 54.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 42095.68 54.0 50000.0 57.0 None False -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 718 HLA-E*01:01 10 QVSEETIKVY 46047.84 42095.68 NetMHC 55.5 54.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 42095.68 54.0 50000.0 57.0 None False -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 718 HLA-E*01:01 10 QVSEETIKVY 46047.84 42095.68 NetMHC 55.5 54.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 42095.68 54.0 50000.0 57.0 None False -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 35 HLA-E*01:01 10 KVKCKLTQSF 38688.63 34986.78 PickPocket 47.0 37.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 26 42390.48 57.0 34986.78 37.0 4 False 0.028571428571428532 0.028571428571428532 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 35 HLA-E*01:01 10 KVKCKLTQSF 38688.63 34986.78 PickPocket 47.0 37.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 26 42390.48 57.0 34986.78 37.0 4 False 0.028571428571428532 0.028571428571428532 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-E*01:01 10 MKSADVVKVK 34671.555 26694.99 PickPocket 42.0 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 19 42648.12 59.0 26694.99 25.0 None False 0.4428571428571429 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-E*01:01 10 MKSADVVKVK 34671.555 26694.99 PickPocket 42.0 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 19 42648.12 59.0 26694.99 25.0 None False 0.4428571428571429 0.8857142857142859 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 758 HLA-E*01:01 10 KKKSEEKELK 40893.36 38984.65 PickPocket 51.5 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 42802.07 60.0 38984.65 43.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 758 HLA-E*01:01 10 KKKSEEKELK 40893.36 38984.65 PickPocket 51.5 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 42802.07 60.0 38984.65 43.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 759 HLA-E*01:01 10 KKKSEEKELK 40893.36 38984.65 PickPocket 51.5 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 42802.07 60.0 38984.65 43.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 759 HLA-E*01:01 10 KKKSEEKELK 40893.36 38984.65 PickPocket 51.5 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 42802.07 60.0 38984.65 43.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 33 HLA-E*01:01 10 VVKVKCKLTQ 33981.22 25017.04 PickPocket 42.0 22.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 24 42945.4 62.0 25017.04 22.0 6 False -0.21428571428571427 0.4857142857142856 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 33 HLA-E*01:01 10 VVKVKCKLTQ 33981.22 25017.04 PickPocket 42.0 22.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 24 42945.4 62.0 25017.04 22.0 6 False -0.21428571428571427 0.4857142857142856 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 32 HLA-E*01:01 10 DVVKVKCKLT 46790.065 43580.13 NetMHC 62.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 23 43580.13 68.0 50000.0 57.0 7 False -0.27142857142857146 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 32 HLA-E*01:01 10 DVVKVKCKLT 46790.065 43580.13 NetMHC 62.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 23 43580.13 68.0 50000.0 57.0 7 False -0.27142857142857146 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 34 HLA-E*01:01 10 VKVKCKLTQS 46826.17 43652.34 NetMHC 62.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 25 43652.34 68.0 50000.0 57.0 5 False -0.9285714285714286 0.42857142857142855 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 34 HLA-E*01:01 10 VKVKCKLTQS 46826.17 43652.34 NetMHC 62.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 25 43652.34 68.0 50000.0 57.0 5 False -0.9285714285714286 0.42857142857142855 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 31 HLA-E*01:01 10 ADVVKVKCKL 35783.375 27875.69 PickPocket 48.0 27.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 22 43691.06 69.0 27875.69 27.0 8 False 0.42857142857142855 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 31 HLA-E*01:01 10 ADVVKVKCKL 35783.375 27875.69 PickPocket 48.0 27.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 22 43691.06 69.0 27875.69 27.0 8 False 0.42857142857142855 0.542857142857143 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 759 HLA-E*01:01 10 KKSEEKELKI 30601.735 17505.31 PickPocket 40.5 12.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 43698.16 69.0 17505.31 12.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 759 HLA-E*01:01 10 KKSEEKELKI 30601.735 17505.31 PickPocket 40.5 12.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 43698.16 69.0 17505.31 12.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 760 HLA-E*01:01 10 KKSEEKELKI 30601.735 17505.31 PickPocket 40.5 12.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 43698.16 69.0 17505.31 12.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 760 HLA-E*01:01 10 KKSEEKELKI 30601.735 17505.31 PickPocket 40.5 12.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 43698.16 69.0 17505.31 12.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-E*01:01 10 KSEEKELKIK 31928.055 19932.31 PickPocket 43.0 15.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 43923.8 71.0 19932.31 15.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-E*01:01 10 KSEEKELKIK 31928.055 19932.31 PickPocket 43.0 15.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 43923.8 71.0 19932.31 15.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-E*01:01 10 KSEEKELKIK 31928.055 19932.31 PickPocket 43.0 15.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 43923.8 71.0 19932.31 15.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-E*01:01 10 KSEEKELKIK 31928.055 19932.31 PickPocket 43.0 15.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 43923.8 71.0 19932.31 15.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 724 HLA-E*01:01 10 KVYCLQKELK 47151.625 44303.25 NetMHC 66.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 8 44303.25 75.0 50000.0 57.0 4 False -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 724 HLA-E*01:01 10 KVYCLQKELK 47151.625 44303.25 NetMHC 66.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 8 44303.25 75.0 50000.0 57.0 4 False -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-E*01:01 10 KVYCLQKELK 47151.625 44303.25 NetMHC 66.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 8 44303.25 75.0 50000.0 57.0 4 False -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-E*01:01 10 KVYCLQKELK 47151.625 44303.25 NetMHC 66.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 8 44303.25 75.0 50000.0 57.0 4 False -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 756 HLA-E*01:01 10 QLKKKSEEKE 37190.42 30068.96 PickPocket 52.5 30.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 44311.88 75.0 30068.96 30.0 None False -3.2857142857142856 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 756 HLA-E*01:01 10 QLKKKSEEKE 37190.42 30068.96 PickPocket 52.5 30.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 44311.88 75.0 30068.96 30.0 None False -3.2857142857142856 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 757 HLA-E*01:01 10 QLKKKSEEKE 37190.42 30068.96 PickPocket 52.5 30.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 44311.88 75.0 30068.96 30.0 None False -3.2857142857142856 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 757 HLA-E*01:01 10 QLKKKSEEKE 37190.42 30068.96 PickPocket 52.5 30.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 44311.88 75.0 30068.96 30.0 None False -3.2857142857142856 -2.242857142857143 True False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 33 HLA-E*01:01 10 VVKQRFKNPA 47279.25 44558.5 NetMHC 67.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 35 44558.5 78.0 50000.0 57.0 None False -1.7714285714285711 -0.6571428571428571 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 33 HLA-E*01:01 10 VVKQRFKNPA 47279.25 44558.5 NetMHC 67.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 35 44558.5 78.0 50000.0 57.0 None False -1.7714285714285711 -0.6571428571428571 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 755 HLA-E*01:01 10 KQLKKKSEEK 36104.265 27575.71 PickPocket 52.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 44632.82 79.0 27575.71 26.0 None False -3.3428571428571425 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 755 HLA-E*01:01 10 KQLKKKSEEK 36104.265 27575.71 PickPocket 52.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 44632.82 79.0 27575.71 26.0 None False -3.3428571428571425 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 756 HLA-E*01:01 10 KQLKKKSEEK 36104.265 27575.71 PickPocket 52.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 44632.82 79.0 27575.71 26.0 None False -3.3428571428571425 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 756 HLA-E*01:01 10 KQLKKKSEEK 36104.265 27575.71 PickPocket 52.5 26.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 44632.82 79.0 27575.71 26.0 None False -3.3428571428571425 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-E*01:01 10 VSEETIKVYC 41639.805 38565.12 PickPocket 61.0 42.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 44714.49 80.0 38565.12 42.0 10 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-E*01:01 10 VSEETIKVYC 41639.805 38565.12 PickPocket 61.0 42.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 44714.49 80.0 38565.12 42.0 10 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-E*01:01 10 VSEETIKVYC 41639.805 38565.12 PickPocket 61.0 42.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 44714.49 80.0 38565.12 42.0 10 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-E*01:01 10 VSEETIKVYC 41639.805 38565.12 PickPocket 61.0 42.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 44714.49 80.0 38565.12 42.0 10 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 28 HLA-E*01:01 10 MKSADVVKQR 36390.37 27875.69 PickPocket 54.5 27.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 30 44905.05 82.0 27875.69 27.0 None False -0.7428571428571428 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 28 HLA-E*01:01 10 MKSADVVKQR 36390.37 27875.69 PickPocket 54.5 27.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 30 44905.05 82.0 27875.69 27.0 None False -0.7428571428571428 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 32 HLA-E*01:01 10 DVVKQRFKNP 47525.52 45051.04 NetMHC 70.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 34 45051.04 84.0 50000.0 57.0 None False -2.585714285714286 -0.6 False False True 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 32 HLA-E*01:01 10 DVVKQRFKNP 47525.52 45051.04 NetMHC 70.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 34 45051.04 84.0 50000.0 57.0 None False -2.585714285714286 -0.6 False False True 0 False 1 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 722 HLA-E*01:01 10 TIKVYCLQKE 39770.14 33869.37 PickPocket 62.5 35.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 45670.91 90.0 33869.37 35.0 6 False -0.24285714285714294 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 722 HLA-E*01:01 10 TIKVYCLQKE 39770.14 33869.37 PickPocket 62.5 35.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 45670.91 90.0 33869.37 35.0 6 False -0.24285714285714294 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 723 HLA-E*01:01 10 TIKVYCLQKE 39770.14 33869.37 PickPocket 62.5 35.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 45670.91 90.0 33869.37 35.0 6 False -0.24285714285714294 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 723 HLA-E*01:01 10 TIKVYCLQKE 39770.14 33869.37 PickPocket 62.5 35.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 45670.91 90.0 33869.37 35.0 6 False -0.24285714285714294 1.3 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 29 HLA-E*01:01 10 KSADVVKQRF 35723.105 25564.3 PickPocket 57.5 23.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 31 45881.91 92.0 25564.3 23.0 None False -0.6 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 29 HLA-E*01:01 10 KSADVVKQRF 35723.105 25564.3 PickPocket 57.5 23.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 31 45881.91 92.0 25564.3 23.0 None False -0.6 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 31 HLA-E*01:01 10 ADVVKQRFKN 36213.66 26407.71 PickPocket 59.5 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 33 46019.61 94.0 26407.71 25.0 None False -1.757142857142857 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 31 HLA-E*01:01 10 ADVVKQRFKN 36213.66 26407.71 PickPocket 59.5 25.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 33 46019.61 94.0 26407.71 25.0 None False -1.757142857142857 -0.6 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 721 HLA-E*01:01 10 ETIKVYCLQK 48024.755 46049.51 NetMHC 75.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 46049.51 94.0 50000.0 57.0 7 False -0.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 721 HLA-E*01:01 10 ETIKVYCLQK 48024.755 46049.51 NetMHC 75.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 46049.51 94.0 50000.0 57.0 7 False -0.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 722 HLA-E*01:01 10 ETIKVYCLQK 48024.755 46049.51 NetMHC 75.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 46049.51 94.0 50000.0 57.0 7 False -0.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 722 HLA-E*01:01 10 ETIKVYCLQK 48024.755 46049.51 NetMHC 75.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 46049.51 94.0 50000.0 57.0 7 False -0.3 1.3 True False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 29 HLA-E*01:01 10 KSADVVKVKC 36980.625 27575.71 PickPocket 61.5 26.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 20 46385.54 97.0 27575.71 26.0 10 False 0.542857142857143 0.8857142857142859 False True False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 29 HLA-E*01:01 10 KSADVVKVKC 36980.625 27575.71 PickPocket 61.5 26.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 20 46385.54 97.0 27575.71 26.0 10 False 0.542857142857143 0.8857142857142859 False True False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 30 HLA-E*01:01 10 SADVVKQRFK 48213.105 46426.21 NetMHC 77.0 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 32 46426.21 97.0 50000.0 57.0 None False -0.6571428571428571 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 30 HLA-E*01:01 10 SADVVKQRFK 48213.105 46426.21 NetMHC 77.0 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 32 46426.21 97.0 50000.0 57.0 None False -0.6571428571428571 -0.21428571428571422 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 761 HLA-E*01:01 10 SEEKELKIKN 48342.81 46685.62 NetMHC 78.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 46685.62 99.0 50000.0 57.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 761 HLA-E*01:01 10 SEEKELKIKN 48342.81 46685.62 NetMHC 78.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 46685.62 99.0 50000.0 57.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 762 HLA-E*01:01 10 SEEKELKIKN 48342.81 46685.62 NetMHC 78.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 46685.62 99.0 50000.0 57.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 762 HLA-E*01:01 10 SEEKELKIKN 48342.81 46685.62 NetMHC 78.0 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 46685.62 99.0 50000.0 57.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 30 HLA-E*01:01 10 SADVVKVKCK 48443.8 46887.6 NetMHC 78.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 21 46887.6 100.0 50000.0 57.0 9 False 0.4857142857142856 0.8857142857142859 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 30 HLA-E*01:01 10 SADVVKVKCK 48443.8 46887.6 NetMHC 78.5 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 21 46887.6 100.0 50000.0 57.0 9 False 0.4857142857142856 0.8857142857142859 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 762 HLA-E*01:01 10 EEKELKIKNH 48560.78 47121.56 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 16 47121.56 100.0 50000.0 57.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 762 HLA-E*01:01 10 EEKELKIKNH 48560.78 47121.56 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 16 47121.56 100.0 50000.0 57.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 763 HLA-E*01:01 10 EEKELKIKNH 48560.78 47121.56 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 16 47121.56 100.0 50000.0 57.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 763 HLA-E*01:01 10 EEKELKIKNH 48560.78 47121.56 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 16 47121.56 100.0 50000.0 57.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 763 HLA-E*01:01 10 EKELKIKNHS 48597.26 47194.52 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 17 47194.52 100.0 50000.0 57.0 None False -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 763 HLA-E*01:01 10 EKELKIKNHS 48597.26 47194.52 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 17 47194.52 100.0 50000.0 57.0 None False -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 764 HLA-E*01:01 10 EKELKIKNHS 48597.26 47194.52 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 17 47194.52 100.0 50000.0 57.0 None False -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 764 HLA-E*01:01 10 EKELKIKNHS 48597.26 47194.52 NetMHC 78.5 57.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 17 47194.52 100.0 50000.0 57.0 None False -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-G*01:09 10 RFKNPAWVWL 5620.54 5620.54 PickPocket 1.8 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 NA NA 5620.54 1.8 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-G*01:09 10 RFKNPAWVWL 5620.54 5620.54 PickPocket 1.8 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 NA NA 5620.54 1.8 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-G*01:09 10 KNPAWVWLWN 7208.66 7208.66 PickPocket 3.0 3.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 41 NA NA 7208.66 3.0 None False 0.5142857142857142 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-G*01:09 10 KNPAWVWLWN 7208.66 7208.66 PickPocket 3.0 3.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 41 NA NA 7208.66 3.0 None False 0.5142857142857142 0.7857142857142857 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 724 HLA-G*01:09 10 KVYCLQKELK 7860.43 7860.43 PickPocket 3.5 3.5 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 8 NA NA 7860.43 3.5 4 False -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 724 HLA-G*01:09 10 KVYCLQKELK 7860.43 7860.43 PickPocket 3.5 3.5 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 8 NA NA 7860.43 3.5 4 False -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-G*01:09 10 KVYCLQKELK 7860.43 7860.43 PickPocket 3.5 3.5 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 8 NA NA 7860.43 3.5 4 False -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-G*01:09 10 KVYCLQKELK 7860.43 7860.43 PickPocket 3.5 3.5 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 8 NA NA 7860.43 3.5 4 False -0.6714285714285714 -0.24285714285714294 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 35 HLA-G*01:09 10 KQRFKNPAWV 11730.27 11730.27 PickPocket 6.7 6.7 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 37 NA NA 11730.27 6.7 None False -0.15714285714285708 -0.15714285714285708 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 35 HLA-G*01:09 10 KQRFKNPAWV 11730.27 11730.27 PickPocket 6.7 6.7 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 37 NA NA 11730.27 6.7 None False -0.15714285714285708 -0.15714285714285708 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 26 HLA-G*01:09 10 HIMKSADVVN 11857.88 11857.88 PickPocket 6.8 6.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 27 NA NA 11857.88 6.8 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 26 HLA-G*01:09 10 HIMKSADVVN 11857.88 11857.88 PickPocket 6.8 6.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 27 NA NA 11857.88 6.8 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 35 HLA-G*01:09 10 KVKCKLTQSF 19717.81 19717.81 PickPocket 16.0 16.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 26 NA NA 19717.81 16.0 4 False 0.028571428571428532 0.028571428571428532 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 35 HLA-G*01:09 10 KVKCKLTQSF 19717.81 19717.81 PickPocket 16.0 16.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 26 NA NA 19717.81 16.0 4 False 0.028571428571428532 0.028571428571428532 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 719 HLA-G*01:09 10 SEETIKVYCL 29108.61 29108.61 PickPocket 25.0 25.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 NA NA 29108.61 25.0 9 False 1.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 719 HLA-G*01:09 10 SEETIKVYCL 29108.61 29108.61 PickPocket 25.0 25.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 NA NA 29108.61 25.0 9 False 1.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 720 HLA-G*01:09 10 SEETIKVYCL 29108.61 29108.61 PickPocket 25.0 25.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 NA NA 29108.61 25.0 9 False 1.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 720 HLA-G*01:09 10 SEETIKVYCL 29108.61 29108.61 PickPocket 25.0 25.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 NA NA 29108.61 25.0 9 False 1.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-G*01:09 10 VSEETIKVYC 32787.64 32787.64 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 NA NA 32787.64 29.0 10 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-G*01:09 10 VSEETIKVYC 32787.64 32787.64 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 NA NA 32787.64 29.0 10 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-G*01:09 10 VSEETIKVYC 32787.64 32787.64 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 NA NA 32787.64 29.0 10 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-G*01:09 10 VSEETIKVYC 32787.64 32787.64 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 NA NA 32787.64 29.0 10 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 755 HLA-G*01:09 10 KQLKKKSEEK 33504.88 33504.88 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 NA NA 33504.88 29.0 None False -3.3428571428571425 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 755 HLA-G*01:09 10 KQLKKKSEEK 33504.88 33504.88 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 NA NA 33504.88 29.0 None False -3.3428571428571425 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 756 HLA-G*01:09 10 KQLKKKSEEK 33504.88 33504.88 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 NA NA 33504.88 29.0 None False -3.3428571428571425 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 756 HLA-G*01:09 10 KQLKKKSEEK 33504.88 33504.88 PickPocket 29.0 29.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 NA NA 33504.88 29.0 None False -3.3428571428571425 -2.242857142857143 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 27 HLA-G*01:09 10 IMKSADVVKV 39408.75 39408.75 PickPocket 35.0 35.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 NA NA 39408.75 35.0 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 27 HLA-G*01:09 10 IMKSADVVKV 39408.75 39408.75 PickPocket 35.0 35.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 NA NA 39408.75 35.0 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-G*01:09 10 KSEEKELKIK 41599.44 41599.44 PickPocket 36.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA 41599.44 36.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-G*01:09 10 KSEEKELKIK 41599.44 41599.44 PickPocket 36.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA 41599.44 36.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-G*01:09 10 KSEEKELKIK 41599.44 41599.44 PickPocket 36.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA 41599.44 36.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-G*01:09 10 KSEEKELKIK 41599.44 41599.44 PickPocket 36.0 36.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA 41599.44 36.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 29 HLA-G*01:09 10 KSADVVKQRF 44872.5 44872.5 PickPocket 39.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 31 NA NA 44872.5 39.0 None False -0.6 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 29 HLA-G*01:09 10 KSADVVKQRF 44872.5 44872.5 PickPocket 39.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 31 NA NA 44872.5 39.0 None False -0.6 -0.21428571428571422 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 717 HLA-G*01:09 10 QVSEETIKVY 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 50000.0 43.0 None False -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 717 HLA-G*01:09 10 QVSEETIKVY 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 50000.0 43.0 None False -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 718 HLA-G*01:09 10 QVSEETIKVY 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 50000.0 43.0 None False -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 718 HLA-G*01:09 10 QVSEETIKVY 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 50000.0 43.0 None False -0.5999999999999999 -0.4714285714285714 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 720 HLA-G*01:09 10 EETIKVYCLQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 NA NA 50000.0 43.0 8 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 720 HLA-G*01:09 10 EETIKVYCLQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 NA NA 50000.0 43.0 8 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 721 HLA-G*01:09 10 EETIKVYCLQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 NA NA 50000.0 43.0 8 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 721 HLA-G*01:09 10 EETIKVYCLQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 NA NA 50000.0 43.0 8 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 721 HLA-G*01:09 10 ETIKVYCLQK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 NA NA 50000.0 43.0 7 False -0.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 721 HLA-G*01:09 10 ETIKVYCLQK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 NA NA 50000.0 43.0 7 False -0.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 722 HLA-G*01:09 10 ETIKVYCLQK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 NA NA 50000.0 43.0 7 False -0.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 722 HLA-G*01:09 10 ETIKVYCLQK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 NA NA 50000.0 43.0 7 False -0.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 722 HLA-G*01:09 10 TIKVYCLQKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 NA NA 50000.0 43.0 6 False -0.24285714285714294 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 722 HLA-G*01:09 10 TIKVYCLQKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 NA NA 50000.0 43.0 6 False -0.24285714285714294 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 723 HLA-G*01:09 10 TIKVYCLQKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 NA NA 50000.0 43.0 6 False -0.24285714285714294 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 723 HLA-G*01:09 10 TIKVYCLQKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 NA NA 50000.0 43.0 6 False -0.24285714285714294 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 723 HLA-G*01:09 10 IKVYCLQKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 NA NA 50000.0 43.0 5 False -0.3000000000000001 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 723 HLA-G*01:09 10 IKVYCLQKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 NA NA 50000.0 43.0 5 False -0.3000000000000001 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 724 HLA-G*01:09 10 IKVYCLQKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 NA NA 50000.0 43.0 5 False -0.3000000000000001 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 724 HLA-G*01:09 10 IKVYCLQKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 NA NA 50000.0 43.0 5 False -0.3000000000000001 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 756 HLA-G*01:09 10 QLKKKSEEKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 NA NA 50000.0 43.0 None False -3.2857142857142856 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 756 HLA-G*01:09 10 QLKKKSEEKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 NA NA 50000.0 43.0 None False -3.2857142857142856 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 757 HLA-G*01:09 10 QLKKKSEEKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 NA NA 50000.0 43.0 None False -3.2857142857142856 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 757 HLA-G*01:09 10 QLKKKSEEKE 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 NA NA 50000.0 43.0 None False -3.2857142857142856 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 757 HLA-G*01:09 10 LKKKSEEKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 NA NA 50000.0 43.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 757 HLA-G*01:09 10 LKKKSEEKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 NA NA 50000.0 43.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 758 HLA-G*01:09 10 LKKKSEEKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 NA NA 50000.0 43.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 758 HLA-G*01:09 10 LKKKSEEKEL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 NA NA 50000.0 43.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 758 HLA-G*01:09 10 KKKSEEKELK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 50000.0 43.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 758 HLA-G*01:09 10 KKKSEEKELK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 50000.0 43.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 759 HLA-G*01:09 10 KKKSEEKELK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 50000.0 43.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 759 HLA-G*01:09 10 KKKSEEKELK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 50000.0 43.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 759 HLA-G*01:09 10 KKSEEKELKI 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 NA NA 50000.0 43.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 759 HLA-G*01:09 10 KKSEEKELKI 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 NA NA 50000.0 43.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 760 HLA-G*01:09 10 KKSEEKELKI 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 NA NA 50000.0 43.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 760 HLA-G*01:09 10 KKSEEKELKI 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 NA NA 50000.0 43.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 761 HLA-G*01:09 10 SEEKELKIKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 NA NA 50000.0 43.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 761 HLA-G*01:09 10 SEEKELKIKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 NA NA 50000.0 43.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 762 HLA-G*01:09 10 SEEKELKIKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 NA NA 50000.0 43.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 762 HLA-G*01:09 10 SEEKELKIKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 NA NA 50000.0 43.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 762 HLA-G*01:09 10 EEKELKIKNH 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 16 NA NA 50000.0 43.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 762 HLA-G*01:09 10 EEKELKIKNH 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 16 NA NA 50000.0 43.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 763 HLA-G*01:09 10 EEKELKIKNH 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 16 NA NA 50000.0 43.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 763 HLA-G*01:09 10 EEKELKIKNH 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 16 NA NA 50000.0 43.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 763 HLA-G*01:09 10 EKELKIKNHS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 17 NA NA 50000.0 43.0 None False -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 763 HLA-G*01:09 10 EKELKIKNHS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 17 NA NA 50000.0 43.0 None False -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 764 HLA-G*01:09 10 EKELKIKNHS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 17 NA NA 50000.0 43.0 None False -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 764 HLA-G*01:09 10 EKELKIKNHS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 17 NA NA 50000.0 43.0 None False -0.9999999999999999 -0.9999999999999999 True False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-G*01:09 10 MKSADVVKVK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 19 NA NA 50000.0 43.0 None False 0.4428571428571429 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-G*01:09 10 MKSADVVKVK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 19 NA NA 50000.0 43.0 None False 0.4428571428571429 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 29 HLA-G*01:09 10 KSADVVKVKC 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 20 NA NA 50000.0 43.0 10 False 0.542857142857143 0.8857142857142859 False True False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 29 HLA-G*01:09 10 KSADVVKVKC 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 20 NA NA 50000.0 43.0 10 False 0.542857142857143 0.8857142857142859 False True False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 30 HLA-G*01:09 10 SADVVKVKCK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 21 NA NA 50000.0 43.0 9 False 0.4857142857142856 0.8857142857142859 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 30 HLA-G*01:09 10 SADVVKVKCK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 21 NA NA 50000.0 43.0 9 False 0.4857142857142856 0.8857142857142859 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 31 HLA-G*01:09 10 ADVVKVKCKL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 22 NA NA 50000.0 43.0 8 False 0.42857142857142855 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 31 HLA-G*01:09 10 ADVVKVKCKL 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 22 NA NA 50000.0 43.0 8 False 0.42857142857142855 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 32 HLA-G*01:09 10 DVVKVKCKLT 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 23 NA NA 50000.0 43.0 7 False -0.27142857142857146 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 32 HLA-G*01:09 10 DVVKVKCKLT 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 23 NA NA 50000.0 43.0 7 False -0.27142857142857146 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 33 HLA-G*01:09 10 VVKVKCKLTQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 24 NA NA 50000.0 43.0 6 False -0.21428571428571427 0.4857142857142856 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 33 HLA-G*01:09 10 VVKVKCKLTQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 24 NA NA 50000.0 43.0 6 False -0.21428571428571427 0.4857142857142856 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 34 HLA-G*01:09 10 VKVKCKLTQS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 25 NA NA 50000.0 43.0 5 False -0.9285714285714286 0.42857142857142855 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 34 HLA-G*01:09 10 VKVKCKLTQS 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 25 NA NA 50000.0 43.0 5 False -0.9285714285714286 0.42857142857142855 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-G*01:09 10 IMKSADVVNR 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 28 NA NA 50000.0 43.0 None False -0.29999999999999993 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-G*01:09 10 IMKSADVVNR 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 28 NA NA 50000.0 43.0 None False -0.29999999999999993 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 27 HLA-G*01:09 10 IMKSADVVKQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 29 NA NA 50000.0 43.0 None False -0.21428571428571422 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 27 HLA-G*01:09 10 IMKSADVVKQ 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 29 NA NA 50000.0 43.0 None False -0.21428571428571422 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 28 HLA-G*01:09 10 MKSADVVKQR 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 30 NA NA 50000.0 43.0 None False -0.7428571428571428 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 28 HLA-G*01:09 10 MKSADVVKQR 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 30 NA NA 50000.0 43.0 None False -0.7428571428571428 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 30 HLA-G*01:09 10 SADVVKQRFK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 32 NA NA 50000.0 43.0 None False -0.6571428571428571 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 30 HLA-G*01:09 10 SADVVKQRFK 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 32 NA NA 50000.0 43.0 None False -0.6571428571428571 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 31 HLA-G*01:09 10 ADVVKQRFKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 33 NA NA 50000.0 43.0 None False -1.757142857142857 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 31 HLA-G*01:09 10 ADVVKQRFKN 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 33 NA NA 50000.0 43.0 None False -1.757142857142857 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 32 HLA-G*01:09 10 DVVKQRFKNP 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 34 NA NA 50000.0 43.0 None False -2.585714285714286 -0.6 False False True 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 32 HLA-G*01:09 10 DVVKQRFKNP 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 34 NA NA 50000.0 43.0 None False -2.585714285714286 -0.6 False False True 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 33 HLA-G*01:09 10 VVKQRFKNPA 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 35 NA NA 50000.0 43.0 None False -1.7714285714285711 -0.6571428571428571 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 33 HLA-G*01:09 10 VVKQRFKNPA 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 35 NA NA 50000.0 43.0 None False -1.7714285714285711 -0.6571428571428571 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 34 HLA-G*01:09 10 VKQRFKNPAW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 36 NA NA 50000.0 43.0 None False -1.4 -1.4 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 34 HLA-G*01:09 10 VKQRFKNPAW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 36 NA NA 50000.0 43.0 None False -1.4 -1.4 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 36 HLA-G*01:09 10 QRFKNPAWVW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 NA NA 50000.0 43.0 None False -0.6857142857142857 -0.15714285714285708 True False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 36 HLA-G*01:09 10 QRFKNPAWVW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 NA NA 50000.0 43.0 None False -0.6857142857142857 -0.15714285714285708 True False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 38 HLA-G*01:09 10 FKNPAWVWLW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 40 NA NA 50000.0 43.0 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 38 HLA-G*01:09 10 FKNPAWVWLW 50000.0 50000.0 PickPocket 43.0 43.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 40 NA NA 50000.0 43.0 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 38 HLA-E*01:01 9 FKNPAWVWL 12055.8 6262.79 PickPocket 6.95 1.9 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 37 17848.81 1.9 6262.79 12.0 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 38 HLA-E*01:01 9 FKNPAWVWL 12055.8 6262.79 PickPocket 6.95 1.9 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 37 17848.81 1.9 6262.79 12.0 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-E*01:01 9 KNPAWVWLW 11362.895 3975.68 PickPocket 3.25 2.3 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 18750.11 2.3 3975.68 4.2 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-E*01:01 9 KNPAWVWLW 11362.895 3975.68 PickPocket 3.25 2.3 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 18750.11 2.3 3975.68 4.2 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-E*01:01 9 IMKSADVVN 14932.635 2842.78 PickPocket 4.2 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 25 27022.49 6.6 2842.78 1.8 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-E*01:01 9 IMKSADVVN 14932.635 2842.78 PickPocket 4.2 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 25 27022.49 6.6 2842.78 1.8 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 35 HLA-E*01:01 9 KQRFKNPAW 14692.5 1765.99 PickPocket 3.8 0.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 34 27619.01 7.1 1765.99 0.5 None False -1.4 -1.4 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 35 HLA-E*01:01 9 KQRFKNPAW 14692.5 1765.99 PickPocket 3.8 0.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 34 27619.01 7.1 1765.99 0.5 None False -1.4 -1.4 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 720 HLA-E*01:01 9 EETIKVYCL 21541.42 14407.49 PickPocket 23.6 8.2 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 28675.35 8.2 14407.49 39.0 8 False 1.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 720 HLA-E*01:01 9 EETIKVYCL 21541.42 14407.49 PickPocket 23.6 8.2 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 28675.35 8.2 14407.49 39.0 8 False 1.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 721 HLA-E*01:01 9 EETIKVYCL 21541.42 14407.49 PickPocket 23.6 8.2 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 28675.35 8.2 14407.49 39.0 8 False 1.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 721 HLA-E*01:01 9 EETIKVYCL 21541.42 14407.49 PickPocket 23.6 8.2 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 28675.35 8.2 14407.49 39.0 8 False 1.3 1.3 True False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-E*01:01 9 RFKNPAWVW 19244.85 8950.22 PickPocket 15.1 9.2 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 36 29539.48 9.2 8950.22 21.0 None False -0.6857142857142857 -0.15714285714285708 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-E*01:01 9 RFKNPAWVW 19244.85 8950.22 PickPocket 15.1 9.2 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 36 29539.48 9.2 8950.22 21.0 None False -0.6857142857142857 -0.15714285714285708 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 758 HLA-E*01:01 9 KKKSEEKEL 21846.13 11112.54 PickPocket 22.0 15.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 32579.72 15.0 11112.54 29.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 758 HLA-E*01:01 9 KKKSEEKEL 21846.13 11112.54 PickPocket 22.0 15.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 32579.72 15.0 11112.54 29.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 759 HLA-E*01:01 9 KKKSEEKEL 21846.13 11112.54 PickPocket 22.0 15.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 32579.72 15.0 11112.54 29.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 759 HLA-E*01:01 9 KKKSEEKEL 21846.13 11112.54 PickPocket 22.0 15.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 32579.72 15.0 11112.54 29.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-E*01:01 9 MKSADVVKV 21064.155 8119.76 PickPocket 18.0 18.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 16 34008.55 18.0 8119.76 18.0 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-E*01:01 9 MKSADVVKV 21064.155 8119.76 PickPocket 18.0 18.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 16 34008.55 18.0 8119.76 18.0 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 34 HLA-E*01:01 9 VKVKCKLTQ 22002.895 9654.43 PickPocket 21.5 19.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 22 34351.36 19.0 9654.43 24.0 5 False -0.21428571428571427 0.42857142857142855 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 34 HLA-E*01:01 9 VKVKCKLTQ 22002.895 9654.43 PickPocket 21.5 19.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 22 34351.36 19.0 9654.43 24.0 5 False -0.21428571428571427 0.42857142857142855 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 36 HLA-E*01:01 9 VKCKLTQSF 30370.74 25842.4 PickPocket 42.0 20.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 24 34899.08 20.0 25842.4 64.0 3 False 0.028571428571428532 0.028571428571428532 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 36 HLA-E*01:01 9 VKCKLTQSF 30370.74 25842.4 PickPocket 42.0 20.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 24 34899.08 20.0 25842.4 64.0 3 False 0.028571428571428532 0.028571428571428532 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 724 HLA-E*01:01 9 KVYCLQKEL 31283.235 26694.99 PickPocket 44.5 23.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 35871.48 23.0 26694.99 66.0 4 False -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 724 HLA-E*01:01 9 KVYCLQKEL 31283.235 26694.99 PickPocket 44.5 23.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 35871.48 23.0 26694.99 66.0 4 False -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-E*01:01 9 KVYCLQKEL 31283.235 26694.99 PickPocket 44.5 23.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 35871.48 23.0 26694.99 66.0 4 False -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-E*01:01 9 KVYCLQKEL 31283.235 26694.99 PickPocket 44.5 23.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 35871.48 23.0 26694.99 66.0 4 False -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 33 HLA-E*01:01 9 VVKVKCKLT 25527.395 14882.82 PickPocket 32.0 24.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 21 36171.97 24.0 14882.82 40.0 6 False -0.27142857142857146 0.4857142857142856 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 33 HLA-E*01:01 9 VVKVKCKLT 25527.395 14882.82 PickPocket 32.0 24.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 21 36171.97 24.0 14882.82 40.0 6 False -0.27142857142857146 0.4857142857142856 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 40 HLA-E*01:01 9 NPAWVWLWN 28278.445 19295.7 PickPocket 39.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 37261.19 28.0 19295.7 51.0 None False 0.5142857142857142 0.7857142857142857 False False False 0 True 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 40 HLA-E*01:01 9 NPAWVWLWN 28278.445 19295.7 PickPocket 39.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 37261.19 28.0 19295.7 51.0 None False 0.5142857142857142 0.7857142857142857 False False False 0 True 1 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 32 HLA-E*01:01 9 DVVKVKCKL 42650.475 37418.75 NetMHC 57.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 20 37418.75 28.0 47882.2 87.0 7 False 0.42857142857142855 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 32 HLA-E*01:01 9 DVVKVKCKL 42650.475 37418.75 NetMHC 57.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 20 37418.75 28.0 47882.2 87.0 7 False 0.42857142857142855 0.542857142857143 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-E*01:01 9 VSEETIKVY 26913.29 16404.99 PickPocket 36.0 28.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 37421.59 28.0 16404.99 44.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-E*01:01 9 VSEETIKVY 26913.29 16404.99 PickPocket 36.0 28.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 37421.59 28.0 16404.99 44.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-E*01:01 9 VSEETIKVY 26913.29 16404.99 PickPocket 36.0 28.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 37421.59 28.0 16404.99 44.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-E*01:01 9 VSEETIKVY 26913.29 16404.99 PickPocket 36.0 28.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 37421.59 28.0 16404.99 44.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 33 HLA-E*01:01 9 VVKQRFKNP 25924.465 14407.49 PickPocket 33.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 32 37441.44 28.0 14407.49 39.0 None False -2.585714285714286 -0.6571428571428571 False False True 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 33 HLA-E*01:01 9 VVKQRFKNP 25924.465 14407.49 PickPocket 33.5 28.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 32 37441.44 28.0 14407.49 39.0 None False -2.585714285714286 -0.6571428571428571 False False True 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 28 HLA-E*01:01 9 MKSADVVKQ 22469.835 7366.35 PickPocket 22.5 16.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 27 37573.32 29.0 7366.35 16.0 None False -0.21428571428571422 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 28 HLA-E*01:01 9 MKSADVVKQ 22469.835 7366.35 PickPocket 22.5 16.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 27 37573.32 29.0 7366.35 16.0 None False -0.21428571428571422 0.5571428571428572 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 37753.86 30.0 2812.19 1.7 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 37753.86 30.0 2812.19 1.7 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 37753.86 30.0 2812.19 1.7 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 37753.86 30.0 2812.19 1.7 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 756 HLA-E*01:01 9 QLKKKSEEK 25845.025 13648.77 PickPocket 34.0 31.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 8 38041.28 31.0 13648.77 37.0 None False -3.3428571428571425 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 756 HLA-E*01:01 9 QLKKKSEEK 25845.025 13648.77 PickPocket 34.0 31.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 8 38041.28 31.0 13648.77 37.0 None False -3.3428571428571425 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 757 HLA-E*01:01 9 QLKKKSEEK 25845.025 13648.77 PickPocket 34.0 31.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 8 38041.28 31.0 13648.77 37.0 None False -3.3428571428571425 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 757 HLA-E*01:01 9 QLKKKSEEK 25845.025 13648.77 PickPocket 34.0 31.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 8 38041.28 31.0 13648.77 37.0 None False -3.3428571428571425 -2.242857142857143 True False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 28 HLA-E*01:01 9 MKSADVVNR 24046.41 8758.62 PickPocket 29.0 21.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 26 39334.2 37.0 8758.62 21.0 None False -0.29999999999999993 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 28 HLA-E*01:01 9 MKSADVVNR 24046.41 8758.62 PickPocket 29.0 21.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 26 39334.2 37.0 8758.62 21.0 None False -0.29999999999999993 0.5571428571428572 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 723 HLA-E*01:01 9 IKVYCLQKE 29432.01 18279.56 PickPocket 46.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 40584.46 44.0 18279.56 49.0 5 False -0.24285714285714294 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 723 HLA-E*01:01 9 IKVYCLQKE 29432.01 18279.56 PickPocket 46.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 40584.46 44.0 18279.56 49.0 5 False -0.24285714285714294 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 724 HLA-E*01:01 9 IKVYCLQKE 29432.01 18279.56 PickPocket 46.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 40584.46 44.0 18279.56 49.0 5 False -0.24285714285714294 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 724 HLA-E*01:01 9 IKVYCLQKE 29432.01 18279.56 PickPocket 46.5 44.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 40584.46 44.0 18279.56 49.0 5 False -0.24285714285714294 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 722 HLA-E*01:01 9 TIKVYCLQK 24506.46 8297.38 PickPocket 31.5 19.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 40715.54 44.0 8297.38 19.0 6 False -0.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 722 HLA-E*01:01 9 TIKVYCLQK 24506.46 8297.38 PickPocket 31.5 19.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 40715.54 44.0 8297.38 19.0 6 False -0.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 723 HLA-E*01:01 9 TIKVYCLQK 24506.46 8297.38 PickPocket 31.5 19.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 40715.54 44.0 8297.38 19.0 6 False -0.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 723 HLA-E*01:01 9 TIKVYCLQK 24506.46 8297.38 PickPocket 31.5 19.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 40715.54 44.0 8297.38 19.0 6 False -0.3 1.3 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 36 HLA-E*01:01 9 QRFKNPAWV 43078.875 40797.1 NetMHC 65.5 45.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 35 40797.1 45.0 45360.65 86.0 None False -0.15714285714285708 -0.15714285714285708 True False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 36 HLA-E*01:01 9 QRFKNPAWV 43078.875 40797.1 NetMHC 65.5 45.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 35 40797.1 45.0 45360.65 86.0 None False -0.15714285714285708 -0.15714285714285708 True False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 34 HLA-E*01:01 9 VKQRFKNPA 36594.955 32085.75 PickPocket 60.5 47.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 33 41104.16 47.0 32085.75 74.0 None False -1.7714285714285711 -1.757142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 34 HLA-E*01:01 9 VKQRFKNPA 36594.955 32085.75 PickPocket 60.5 47.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 33 41104.16 47.0 32085.75 74.0 None False -1.7714285714285711 -1.757142857142857 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 759 HLA-E*01:01 9 KKSEEKELK 30625.595 19088.05 PickPocket 53.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 42163.14 55.0 19088.05 51.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 759 HLA-E*01:01 9 KKSEEKELK 30625.595 19088.05 PickPocket 53.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 42163.14 55.0 19088.05 51.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 760 HLA-E*01:01 9 KKSEEKELK 30625.595 19088.05 PickPocket 53.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 42163.14 55.0 19088.05 51.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 760 HLA-E*01:01 9 KKSEEKELK 30625.595 19088.05 PickPocket 53.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 42163.14 55.0 19088.05 51.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 721 HLA-E*01:01 9 ETIKVYCLQ 46120.845 42241.69 NetMHC 72.0 56.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 42241.69 56.0 50000.0 88.0 7 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 721 HLA-E*01:01 9 ETIKVYCLQ 46120.845 42241.69 NetMHC 72.0 56.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 42241.69 56.0 50000.0 88.0 7 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 722 HLA-E*01:01 9 ETIKVYCLQ 46120.845 42241.69 NetMHC 72.0 56.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 42241.69 56.0 50000.0 88.0 7 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 722 HLA-E*01:01 9 ETIKVYCLQ 46120.845 42241.69 NetMHC 72.0 56.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 42241.69 56.0 50000.0 88.0 7 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 30 HLA-E*01:01 9 SADVVKQRF 37899.345 33504.88 PickPocket 65.5 56.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 29 42293.81 56.0 33504.88 75.0 None False -0.6 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 30 HLA-E*01:01 9 SADVVKQRF 37899.345 33504.88 PickPocket 65.5 56.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 29 42293.81 56.0 33504.88 75.0 None False -0.6 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 32 HLA-E*01:01 9 DVVKQRFKN 35416.435 28485.48 PickPocket 63.0 57.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 31 42347.39 57.0 28485.48 69.0 None False -1.757142857142857 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 32 HLA-E*01:01 9 DVVKQRFKN 35416.435 28485.48 PickPocket 63.0 57.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 31 42347.39 57.0 28485.48 69.0 None False -1.757142857142857 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 29 HLA-E*01:01 9 KSADVVKVK 28151.725 13947.35 PickPocket 47.0 37.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 17 42356.1 57.0 13947.35 37.0 None False 0.4428571428571429 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 29 HLA-E*01:01 9 KSADVVKVK 28151.725 13947.35 PickPocket 47.0 37.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 17 42356.1 57.0 13947.35 37.0 None False 0.4428571428571429 0.8857142857142859 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 757 HLA-E*01:01 9 LKKKSEEKE 27609.175 12653.21 PickPocket 46.0 34.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 42565.14 58.0 12653.21 34.0 None False -3.2857142857142856 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 757 HLA-E*01:01 9 LKKKSEEKE 27609.175 12653.21 PickPocket 46.0 34.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 42565.14 58.0 12653.21 34.0 None False -3.2857142857142856 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 758 HLA-E*01:01 9 LKKKSEEKE 27609.175 12653.21 PickPocket 46.0 34.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 42565.14 58.0 12653.21 34.0 None False -3.2857142857142856 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 758 HLA-E*01:01 9 LKKKSEEKE 27609.175 12653.21 PickPocket 46.0 34.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 42565.14 58.0 12653.21 34.0 None False -3.2857142857142856 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 761 HLA-E*01:01 9 SEEKELKIK 42009.35 41151.77 PickPocket 72.0 61.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 42866.93 61.0 41151.77 83.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 761 HLA-E*01:01 9 SEEKELKIK 42009.35 41151.77 PickPocket 72.0 61.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 42866.93 61.0 41151.77 83.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 762 HLA-E*01:01 9 SEEKELKIK 42009.35 41151.77 PickPocket 72.0 61.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 42866.93 61.0 41151.77 83.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 762 HLA-E*01:01 9 SEEKELKIK 42009.35 41151.77 PickPocket 72.0 61.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 42866.93 61.0 41151.77 83.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 31 HLA-E*01:01 9 ADVVKQRFK 30344.565 17316.93 PickPocket 56.5 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 30 43372.2 66.0 17316.93 47.0 None False -0.6571428571428571 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 31 HLA-E*01:01 9 ADVVKQRFK 30344.565 17316.93 PickPocket 56.5 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 30 43372.2 66.0 17316.93 47.0 None False -0.6571428571428571 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 31 HLA-E*01:01 9 ADVVKVKCK 28952.59 14407.49 PickPocket 53.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 19 43497.69 67.0 14407.49 39.0 8 False 0.4857142857142856 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 31 HLA-E*01:01 9 ADVVKVKCK 28952.59 14407.49 PickPocket 53.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 19 43497.69 67.0 14407.49 39.0 8 False 0.4857142857142856 0.542857142857143 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 719 HLA-E*01:01 9 SEETIKVYC 37717.65 31740.46 PickPocket 71.0 69.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 43694.84 69.0 31740.46 73.0 9 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 719 HLA-E*01:01 9 SEETIKVYC 37717.65 31740.46 PickPocket 71.0 69.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 43694.84 69.0 31740.46 73.0 9 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 720 HLA-E*01:01 9 SEETIKVYC 37717.65 31740.46 PickPocket 71.0 69.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 43694.84 69.0 31740.46 73.0 9 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 720 HLA-E*01:01 9 SEETIKVYC 37717.65 31740.46 PickPocket 71.0 69.0 NetMHC 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 43694.84 69.0 31740.46 73.0 9 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 29 HLA-E*01:01 9 KSADVVKQR 29130.49 14564.23 PickPocket 54.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 28 43696.75 69.0 14564.23 39.0 None False -0.7428571428571428 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 29 HLA-E*01:01 9 KSADVVKQR 29130.49 14564.23 PickPocket 54.0 39.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 28 43696.75 69.0 14564.23 39.0 None False -0.7428571428571428 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 35 HLA-E*01:01 9 KVKCKLTQS 32815.365 21734.48 PickPocket 64.0 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 23 43896.25 71.0 21734.48 57.0 4 False -0.9285714285714286 -0.21428571428571427 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 35 HLA-E*01:01 9 KVKCKLTQS 32815.365 21734.48 PickPocket 64.0 57.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 23 43896.25 71.0 21734.48 57.0 4 False -0.9285714285714286 -0.21428571428571427 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 763 HLA-E*01:01 9 EKELKIKNH 33564.085 22942.68 PickPocket 66.5 59.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 44185.49 74.0 22942.68 59.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 763 HLA-E*01:01 9 EKELKIKNH 33564.085 22942.68 PickPocket 66.5 59.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 44185.49 74.0 22942.68 59.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 764 HLA-E*01:01 9 EKELKIKNH 33564.085 22942.68 PickPocket 66.5 59.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 44185.49 74.0 22942.68 59.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 764 HLA-E*01:01 9 EKELKIKNH 33564.085 22942.68 PickPocket 66.5 59.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 44185.49 74.0 22942.68 59.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 30 HLA-E*01:01 9 SADVVKVKC 38984.985 33504.88 PickPocket 76.0 75.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 44465.09 77.0 33504.88 75.0 9 False 0.542857142857143 0.8857142857142859 False True False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 30 HLA-E*01:01 9 SADVVKVKC 38984.985 33504.88 PickPocket 76.0 75.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 44465.09 77.0 33504.88 75.0 9 False 0.542857142857143 0.8857142857142859 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 762 HLA-E*01:01 9 EEKELKIKN 37817.35 30726.73 PickPocket 77.0 72.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 44907.97 82.0 30726.73 72.0 None False -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 762 HLA-E*01:01 9 EEKELKIKN 37817.35 30726.73 PickPocket 77.0 72.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 44907.97 82.0 30726.73 72.0 None False -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 763 HLA-E*01:01 9 EEKELKIKN 37817.35 30726.73 PickPocket 77.0 72.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 44907.97 82.0 30726.73 72.0 None False -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 763 HLA-E*01:01 9 EEKELKIKN 37817.35 30726.73 PickPocket 77.0 72.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 44907.97 82.0 30726.73 72.0 None False -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 724 HLA-G*01:09 9 KVYCLQKEL 645.63 645.63 PickPocket 0.2 0.2 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 NA NA 645.63 0.2 4 False -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 724 HLA-G*01:09 9 KVYCLQKEL 645.63 645.63 PickPocket 0.2 0.2 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 NA NA 645.63 0.2 4 False -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 725 HLA-G*01:09 9 KVYCLQKEL 645.63 645.63 PickPocket 0.2 0.2 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 NA NA 645.63 0.2 4 False -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 725 HLA-G*01:09 9 KVYCLQKEL 645.63 645.63 PickPocket 0.2 0.2 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 7 NA NA 645.63 0.2 4 False -0.3000000000000001 -0.24285714285714294 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-G*01:09 9 KNPAWVWLW 5099.03 5099.03 PickPocket 7.5 7.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 NA NA 5099.03 7.5 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-G*01:09 9 KNPAWVWLW 5099.03 5099.03 PickPocket 7.5 7.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 NA NA 5099.03 7.5 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-G*01:09 9 RFKNPAWVW 9447.76 9447.76 PickPocket 19.0 19.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 36 NA NA 9447.76 19.0 None False -0.6857142857142857 -0.15714285714285708 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-G*01:09 9 RFKNPAWVW 9447.76 9447.76 PickPocket 19.0 19.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 36 NA NA 9447.76 19.0 None False -0.6857142857142857 -0.15714285714285708 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 9759.45 20.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 9759.45 20.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 9759.45 20.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 9759.45 20.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 35 HLA-G*01:09 9 KQRFKNPAW 12653.21 12653.21 PickPocket 26.0 26.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 34 NA NA 12653.21 26.0 None False -1.4 -1.4 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 35 HLA-G*01:09 9 KQRFKNPAW 12653.21 12653.21 PickPocket 26.0 26.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 34 NA NA 12653.21 26.0 None False -1.4 -1.4 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-G*01:09 9 IMKSADVVN 16053.81 16053.81 PickPocket 33.0 33.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 25 NA NA 16053.81 33.0 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-G*01:09 9 IMKSADVVN 16053.81 16053.81 PickPocket 33.0 33.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 25 NA NA 16053.81 33.0 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 38 HLA-G*01:09 9 FKNPAWVWL 16583.46 16583.46 PickPocket 34.0 34.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 37 NA NA 16583.46 34.0 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 38 HLA-G*01:09 9 FKNPAWVWL 16583.46 16583.46 PickPocket 34.0 34.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 37 NA NA 16583.46 34.0 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 35 HLA-G*01:09 9 KVKCKLTQS 21734.48 21734.48 PickPocket 44.0 44.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 23 NA NA 21734.48 44.0 4 False -0.9285714285714286 -0.21428571428571427 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 35 HLA-G*01:09 9 KVKCKLTQS 21734.48 21734.48 PickPocket 44.0 44.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 23 NA NA 21734.48 44.0 4 False -0.9285714285714286 -0.21428571428571427 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 36 HLA-G*01:09 9 QRFKNPAWV 22209.93 22209.93 PickPocket 44.0 44.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 35 NA NA 22209.93 44.0 None False -0.15714285714285708 -0.15714285714285708 True False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 36 HLA-G*01:09 9 QRFKNPAWV 22209.93 22209.93 PickPocket 44.0 44.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 35 NA NA 22209.93 44.0 None False -0.15714285714285708 -0.15714285714285708 True False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 719 HLA-G*01:09 9 SEETIKVYC 23192.26 23192.26 PickPocket 46.0 46.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 NA NA 23192.26 46.0 9 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 719 HLA-G*01:09 9 SEETIKVYC 23192.26 23192.26 PickPocket 46.0 46.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 NA NA 23192.26 46.0 9 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 720 HLA-G*01:09 9 SEETIKVYC 23192.26 23192.26 PickPocket 46.0 46.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 NA NA 23192.26 46.0 9 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 720 HLA-G*01:09 9 SEETIKVYC 23192.26 23192.26 PickPocket 46.0 46.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 2 NA NA 23192.26 46.0 9 False 0.2571428571428572 0.2571428571428572 False True False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 30 HLA-G*01:09 9 SADVVKQRF 23699.6 23699.6 PickPocket 47.0 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 29 NA NA 23699.6 47.0 None False -0.6 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 30 HLA-G*01:09 9 SADVVKQRF 23699.6 23699.6 PickPocket 47.0 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 29 NA NA 23699.6 47.0 None False -0.6 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 29 HLA-G*01:09 9 KSADVVKVK 23957.42 23957.42 PickPocket 47.0 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 17 NA NA 23957.42 47.0 None False 0.4428571428571429 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 29 HLA-G*01:09 9 KSADVVKVK 23957.42 23957.42 PickPocket 47.0 47.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 17 NA NA 23957.42 47.0 None False 0.4428571428571429 0.8857142857142859 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 758 HLA-G*01:09 9 KKKSEEKEL 26694.99 26694.99 PickPocket 51.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 NA NA 26694.99 51.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 758 HLA-G*01:09 9 KKKSEEKEL 26694.99 26694.99 PickPocket 51.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 NA NA 26694.99 51.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 759 HLA-G*01:09 9 KKKSEEKEL 26694.99 26694.99 PickPocket 51.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 NA NA 26694.99 51.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 759 HLA-G*01:09 9 KKKSEEKEL 26694.99 26694.99 PickPocket 51.0 51.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 10 NA NA 26694.99 51.0 None False -2.185714285714286 -2.185714285714286 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 34 HLA-G*01:09 9 VKQRFKNPA 33144.32 33144.32 PickPocket 59.0 59.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 33 NA NA 33144.32 59.0 None False -1.7714285714285711 -1.757142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 34 HLA-G*01:09 9 VKQRFKNPA 33144.32 33144.32 PickPocket 59.0 59.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 33 NA NA 33144.32 59.0 None False -1.7714285714285711 -1.757142857142857 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 722 HLA-G*01:09 9 TIKVYCLQK 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 NA NA 37333.42 64.0 6 False -0.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 722 HLA-G*01:09 9 TIKVYCLQK 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 NA NA 37333.42 64.0 6 False -0.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 723 HLA-G*01:09 9 TIKVYCLQK 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 NA NA 37333.42 64.0 6 False -0.3 1.3 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 723 HLA-G*01:09 9 TIKVYCLQK 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 5 NA NA 37333.42 64.0 6 False -0.3 1.3 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 33 HLA-G*01:09 9 VVKQRFKNP 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 32 NA NA 37333.42 64.0 None False -2.585714285714286 -0.6571428571428571 False False True 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 33 HLA-G*01:09 9 VVKQRFKNP 37333.42 37333.42 PickPocket 64.0 64.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 32 NA NA 37333.42 64.0 None False -2.585714285714286 -0.6571428571428571 False False True 0 False 1 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 36 HLA-G*01:09 9 VKCKLTQSF 38984.65 38984.65 PickPocket 65.0 65.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 24 NA NA 38984.65 65.0 3 False 0.028571428571428532 0.028571428571428532 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 36 HLA-G*01:09 9 VKCKLTQSF 38984.65 38984.65 PickPocket 65.0 65.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 24 NA NA 38984.65 65.0 3 False 0.028571428571428532 0.028571428571428532 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 29 HLA-G*01:09 9 KSADVVKQR 41151.77 41151.77 PickPocket 67.0 67.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 28 NA NA 41151.77 67.0 None False -0.7428571428571428 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 29 HLA-G*01:09 9 KSADVVKQR 41151.77 41151.77 PickPocket 67.0 67.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 28 NA NA 41151.77 67.0 None False -0.7428571428571428 -0.21428571428571422 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 33 HLA-G*01:09 9 VVKVKCKLT 43911.91 43911.91 PickPocket 69.0 69.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 21 NA NA 43911.91 69.0 6 False -0.27142857142857146 0.4857142857142856 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 33 HLA-G*01:09 9 VVKVKCKLT 43911.91 43911.91 PickPocket 69.0 69.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 21 NA NA 43911.91 69.0 6 False -0.27142857142857146 0.4857142857142856 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 721 HLA-G*01:09 9 ETIKVYCLQ 45854.11 45854.11 PickPocket 70.0 70.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 NA NA 45854.11 70.0 7 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 721 HLA-G*01:09 9 ETIKVYCLQ 45854.11 45854.11 PickPocket 70.0 70.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 NA NA 45854.11 70.0 7 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 722 HLA-G*01:09 9 ETIKVYCLQ 45854.11 45854.11 PickPocket 70.0 70.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 NA NA 45854.11 70.0 7 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 722 HLA-G*01:09 9 ETIKVYCLQ 45854.11 45854.11 PickPocket 70.0 70.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 4 NA NA 45854.11 70.0 7 False 0.9000000000000001 1.3 True False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 30 HLA-G*01:09 9 SADVVKVKC 48929.64 48929.64 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 NA NA 48929.64 73.0 9 False 0.542857142857143 0.8857142857142859 False True False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 30 HLA-G*01:09 9 SADVVKVKC 48929.64 48929.64 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 NA NA 48929.64 73.0 9 False 0.542857142857143 0.8857142857142859 False True False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 720 HLA-G*01:09 9 EETIKVYCL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 NA NA 50000.0 73.0 8 False 1.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 720 HLA-G*01:09 9 EETIKVYCL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 NA NA 50000.0 73.0 8 False 1.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 721 HLA-G*01:09 9 EETIKVYCL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 NA NA 50000.0 73.0 8 False 1.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 721 HLA-G*01:09 9 EETIKVYCL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 3 NA NA 50000.0 73.0 8 False 1.3 1.3 True False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 723 HLA-G*01:09 9 IKVYCLQKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 NA NA 50000.0 73.0 5 False -0.24285714285714294 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 723 HLA-G*01:09 9 IKVYCLQKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 NA NA 50000.0 73.0 5 False -0.24285714285714294 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 724 HLA-G*01:09 9 IKVYCLQKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 NA NA 50000.0 73.0 5 False -0.24285714285714294 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 724 HLA-G*01:09 9 IKVYCLQKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 6 NA NA 50000.0 73.0 5 False -0.24285714285714294 0.9000000000000001 False False False 1 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 756 HLA-G*01:09 9 QLKKKSEEK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 8 NA NA 50000.0 73.0 None False -3.3428571428571425 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 756 HLA-G*01:09 9 QLKKKSEEK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 8 NA NA 50000.0 73.0 None False -3.3428571428571425 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 757 HLA-G*01:09 9 QLKKKSEEK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 8 NA NA 50000.0 73.0 None False -3.3428571428571425 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 757 HLA-G*01:09 9 QLKKKSEEK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 8 NA NA 50000.0 73.0 None False -3.3428571428571425 -2.242857142857143 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 757 HLA-G*01:09 9 LKKKSEEKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 NA NA 50000.0 73.0 None False -3.2857142857142856 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 757 HLA-G*01:09 9 LKKKSEEKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 NA NA 50000.0 73.0 None False -3.2857142857142856 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 758 HLA-G*01:09 9 LKKKSEEKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 NA NA 50000.0 73.0 None False -3.2857142857142856 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 758 HLA-G*01:09 9 LKKKSEEKE 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 9 NA NA 50000.0 73.0 None False -3.2857142857142856 -2.242857142857143 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 759 HLA-G*01:09 9 KKSEEKELK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 NA NA 50000.0 73.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 759 HLA-G*01:09 9 KKSEEKELK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 NA NA 50000.0 73.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 760 HLA-G*01:09 9 KKSEEKELK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 NA NA 50000.0 73.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 760 HLA-G*01:09 9 KKSEEKELK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 11 NA NA 50000.0 73.0 None False -2.1857142857142855 -2.1857142857142855 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 761 HLA-G*01:09 9 SEEKELKIK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 NA NA 50000.0 73.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 761 HLA-G*01:09 9 SEEKELKIK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 NA NA 50000.0 73.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 762 HLA-G*01:09 9 SEEKELKIK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 NA NA 50000.0 73.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 762 HLA-G*01:09 9 SEEKELKIK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 13 NA NA 50000.0 73.0 None False -1.4857142857142858 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 762 HLA-G*01:09 9 EEKELKIKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA 50000.0 73.0 None False -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 762 HLA-G*01:09 9 EEKELKIKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA 50000.0 73.0 None False -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 763 HLA-G*01:09 9 EEKELKIKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA 50000.0 73.0 None False -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 763 HLA-G*01:09 9 EEKELKIKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 14 NA NA 50000.0 73.0 None False -1.4857142857142858 -1.4285714285714288 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 763 HLA-G*01:09 9 EKELKIKNH 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 NA NA 50000.0 73.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 763 HLA-G*01:09 9 EKELKIKNH 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 NA NA 50000.0 73.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 764 HLA-G*01:09 9 EKELKIKNH 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 NA NA 50000.0 73.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 764 HLA-G*01:09 9 EKELKIKNH 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 15 NA NA 50000.0 73.0 None False -1.3857142857142857 -1.3857142857142857 True False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-G*01:09 9 MKSADVVKV 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 16 NA NA 50000.0 73.0 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-G*01:09 9 MKSADVVKV 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 16 NA NA 50000.0 73.0 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 31 HLA-G*01:09 9 ADVVKVKCK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 19 NA NA 50000.0 73.0 8 False 0.4857142857142856 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 31 HLA-G*01:09 9 ADVVKVKCK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 19 NA NA 50000.0 73.0 8 False 0.4857142857142856 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 32 HLA-G*01:09 9 DVVKVKCKL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 20 NA NA 50000.0 73.0 7 False 0.42857142857142855 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 32 HLA-G*01:09 9 DVVKVKCKL 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 20 NA NA 50000.0 73.0 7 False 0.42857142857142855 0.542857142857143 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 34 HLA-G*01:09 9 VKVKCKLTQ 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 22 NA NA 50000.0 73.0 5 False -0.21428571428571427 0.42857142857142855 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 34 HLA-G*01:09 9 VKVKCKLTQ 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 22 NA NA 50000.0 73.0 5 False -0.21428571428571427 0.42857142857142855 False False False 1 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 28 HLA-G*01:09 9 MKSADVVNR 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 26 NA NA 50000.0 73.0 None False -0.29999999999999993 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 28 HLA-G*01:09 9 MKSADVVNR 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 26 NA NA 50000.0 73.0 None False -0.29999999999999993 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 28 HLA-G*01:09 9 MKSADVVKQ 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 27 NA NA 50000.0 73.0 None False -0.21428571428571422 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 28 HLA-G*01:09 9 MKSADVVKQ 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 27 NA NA 50000.0 73.0 None False -0.21428571428571422 0.5571428571428572 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 31 HLA-G*01:09 9 ADVVKQRFK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 30 NA NA 50000.0 73.0 None False -0.6571428571428571 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 31 HLA-G*01:09 9 ADVVKQRFK 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 30 NA NA 50000.0 73.0 None False -0.6571428571428571 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 32 HLA-G*01:09 9 DVVKQRFKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 31 NA NA 50000.0 73.0 None False -1.757142857142857 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 32 HLA-G*01:09 9 DVVKQRFKN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 31 NA NA 50000.0 73.0 None False -1.757142857142857 -0.6 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 40 HLA-G*01:09 9 NPAWVWLWN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 NA NA 50000.0 73.0 None False 0.5142857142857142 0.7857142857142857 False False False 0 True 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 40 HLA-G*01:09 9 NPAWVWLWN 50000.0 50000.0 PickPocket 73.0 73.0 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 NA NA 50000.0 73.0 None False 0.5142857142857142 0.7857142857142857 False False False 0 True 1 diff --git a/tests/test_data/top_score_filter/output_HCC1395.tsv b/tests/test_data/top_score_filter/output_HCC1395.tsv index 986d4895c..20c657a91 100644 --- a/tests/test_data/top_score_filter/output_HCC1395.tsv +++ b/tests/test_data/top_score_filter/output_HCC1395.tsv @@ -50,7 +50,7 @@ chr19 16093698 16093699 G C ENST00000647464.2 NA 248 False False protein_coding chr10 60186848 60186849 G T ENST00000280772.7 1 4377 True True protein_coding None ENSG00000151150 missense L/M 651 ANK3 ENST00000280772.7:c.1951C>A ENSP00000280772.1:p.Leu651Met HLA-B*45:01 10 10 1 MEYGADANAV LEYGADANAV MHCflurry 76.313 124.611 1.633 MHCflurry 0.154 0.316 149 0.134 0 0.0 191 0.0 0.163 0.013 193.555 749.92 3.874 0.333 1.03 0.0077834013 0.021770393 0.0027470018 0.0033213687 0.1315616713836789 0.2275329306721687 0.5255847389203251 0.7146940332311534 0.7659510869564059 0.4152717391304463 124.61066067029122 76.31289727522126 0.3158749999999998 0.1545 629.04 158.48 1.48 0.61 843.65 170.99 1.2 0.25 656.19 141.18 0.86 0.24 1260.22 227.26 0.72 0.21 0.0667 0.176 1.3 0.66 638.68 302.73 0.6 0.2 1689.23 216.12 6.6 0.6 1428.66 227.47 5.6 0.7 577.ANK3.ENST00000280772.7.missense.651L/M NA NA None 0.31428571428571433 0.31428571428571433 False False False 0 False 0 chr11 59364558 59364559 T A ENST00000641998.1 NA 311 True True protein_coding None ENSG00000176495 missense V/E 34 OR5AN1 ENST00000641998.1:c.101T>A ENSP00000493250.1:p.Val34Glu HLA-B*45:01 9 8 2 LEIYITSLA LVIYITSLA MHCnuggetsI 62.74 14301.89 227.955 NetMHCpan 0.09 12.0 249 0.116 0 0.0 137 0.0 0.154 0.154 199.865 18565.46 92.89 0.47 19.595 0.0005662339 0.012015799 0.011528974 0.0011933909 0.002823315851856 0.0169515103916637 0.0037302071700682 0.4680509170155289 99.28660326086955 0.8930706521738045 27284.046012300558 104.05540643404782 18.189125 0.2538749999999998 14301.89 62.74 14.95 0.3 32389.2 187.59 26.0 0.27 38357.05 271.69 38.0 0.64 22829.03 71.0 12.0 0.09 0.000179 0.377 21.0 0.29 12382.34 283.7 34.0 0.7 6671.29 227.1 18.0 0.9 5696.66 212.14 17.0 0.9 648.OR5AN1.ENST00000641998.1.missense.34V/E NA NA None 1.6857142857142857 1.6857142857142857 False False False 0 False 0 chr1 154590262 154590263 T A ENST00000368471.8 1 931 False False protein_coding None ENSG00000160710 missense E/V 511 ADAR ENST00000368471.8:c.1532A>T ENSP00000357456.3:p.Glu511Val HLA-B*45:01 10 3 8 AERMGFTVVT AERMGFTEVT NetMHC 22.44 42.62 1.899 NetMHC 0.03 0.06 149 0.302 1233 0.348 139 0.007 131.835 36.828 214.664 219.26 1.021 0.33 0.462 0.18812804 0.034368556 0.014715277 0.0029568933 0.2832114603370428 0.3730203146114945 0.5144309887378682 0.5231498188416924 0.7930434782607136 0.7725815217389993 226.68944851048937 303.3089523399954 0.5342499999999998 0.6408749999999996 86.69 36.58 0.3899999999999999 0.1699999999999999 42.62 22.44 0.06 0.03 211.83 126.02 0.35 0.21 54.92 23.99 0.08 0.04 0.346 0.407 0.32 0.26 605.05 409.85 0.6 0.4 626.17 599.36 2.4 2.2 398.04 385.42 1.3 1.3 52.ADAR.ENST00000368471.8.missense.511E/V NA NA None 1.6142857142857143 1.6142857142857143 False False False 0 False 0 -chr1 154590262 154590263 T A ENST00000681056.1 NA 931 False False protein_coding None ENSG00000160710 missense E/V 511 ADAR ENST00000681056.1:c.1532A>T ENSP00000506234.1:p.Glu511Val HLA-B*45:01 10 3 8 AERMGFTVVT AERMGFTEVT NetMHC 22.44 42.62 1.899 NetMHC 0.03 0.06 149 0.302 1233 0.348 139 0.007 131.835 0.041 214.664 219.26 1.021 0.33 0.462 0.18812804 0.034368556 0.014715277 0.0029568933 0.2832114603370428 0.3730203146114945 0.5144309887378682 0.5231498188416924 0.7930434782607136 0.7725815217389993 226.68944851048937 303.3089523399954 0.5342499999999998 0.6408749999999996 86.69 36.58 0.3899999999999999 0.1699999999999999 42.62 22.44 0.06 0.03 211.83 126.02 0.35 0.21 54.92 23.99 0.08 0.04 0.346 0.407 0.32 0.26 605.05 409.85 0.6 0.4 626.17 599.36 2.4 2.2 398.04 385.42 1.3 1.3 65.ADAR.ENST00000681056.1.missense.511E/V NA NA None 1.6142857142857143 1.6142857142857143 False False False 0 False 0 +chr1 154590262 154590263 T A ENST00000368474.9 1 1226 True True protein_coding None ENSG00000160710 missense E/V 806 ADAR ENST00000368474.9:c.2417A>T ENSP00000357459.4:p.Glu806Val HLA-B*45:01 10 3 8 AERMGFTVVT AERMGFTEVT NetMHC 22.44 42.62 1.899 NetMHC 0.03 0.06 149 0.302 1233 0.348 139 0.007 131.835 29.266 214.664 219.26 1.021 0.33 0.462 0.18812804 0.034368556 0.014715277 0.0029568933 0.2832114603370428 0.3730203146114945 0.5144309887378682 0.5231498188416924 0.7930434782607136 0.7725815217389993 226.68944851048937 303.3089523399954 0.5342499999999998 0.6408749999999996 86.69 36.58 0.3899999999999999 0.1699999999999999 42.62 22.44 0.06 0.03 211.83 126.02 0.35 0.21 54.92 23.99 0.08 0.04 0.346 0.407 0.32 0.26 605.05 409.85 0.6 0.4 626.17 599.36 2.4 2.2 398.04 385.42 1.3 1.3 53.ADAR.ENST00000368474.9.missense.806E/V NA NA None 1.6142857142857143 1.6142857142857143 False False False 0 False 0 chr1 154590262 154590263 T A ENST00000649749.1 NA 931 False False protein_coding None ENSG00000160710 missense E/V 511 ADAR ENST00000649749.1:c.1532A>T ENSP00000497210.1:p.Glu511Val HLA-B*45:01 10 3 8 AERMGFTVVT AERMGFTEVT NetMHC 22.44 42.62 1.899 NetMHC 0.03 0.06 149 0.302 1233 0.348 139 0.007 131.835 0.0 214.664 219.26 1.021 0.33 0.462 0.18812804 0.034368556 0.014715277 0.0029568933 0.2832114603370428 0.3730203146114945 0.5144309887378682 0.5231498188416924 0.7930434782607136 0.7725815217389993 226.68944851048937 303.3089523399954 0.5342499999999998 0.6408749999999996 86.69 36.58 0.3899999999999999 0.1699999999999999 42.62 22.44 0.06 0.03 211.83 126.02 0.35 0.21 54.92 23.99 0.08 0.04 0.346 0.407 0.32 0.26 605.05 409.85 0.6 0.4 626.17 599.36 2.4 2.2 398.04 385.42 1.3 1.3 61.ADAR.ENST00000649749.1.missense.511E/V NA NA None 1.6142857142857143 1.6142857142857143 False False False 0 False 0 chr1 154590262 154590263 T A ENST00000679899.1 NA 912 False False protein_coding None ENSG00000160710 missense E/V 492 ADAR ENST00000679899.1:c.1475A>T ENSP00000505996.1:p.Glu492Val HLA-B*45:01 10 3 8 AERMGFTVVT AERMGFTEVT NetMHC 22.44 42.62 1.899 NetMHC 0.03 0.06 149 0.302 1233 0.348 139 0.007 131.835 0.852 214.664 219.26 1.021 0.33 0.462 0.18812804 0.034368556 0.014715277 0.0029568933 0.2832114603370428 0.3730203146114945 0.5144309887378682 0.5231498188416924 0.7930434782607136 0.7725815217389993 226.68944851048937 303.3089523399954 0.5342499999999998 0.6408749999999996 86.69 36.58 0.3899999999999999 0.1699999999999999 42.62 22.44 0.06 0.03 211.83 126.02 0.35 0.21 54.92 23.99 0.08 0.04 0.346 0.407 0.32 0.26 605.05 409.85 0.6 0.4 626.17 599.36 2.4 2.2 398.04 385.42 1.3 1.3 62.ADAR.ENST00000679899.1.missense.492E/V NA NA None 1.6142857142857143 1.6142857142857143 False False False 0 False 0 chr1 154590262 154590263 T A ENST00000680270.1 NA 931 False False protein_coding None ENSG00000160710 missense E/V 511 ADAR ENST00000680270.1:c.1532A>T ENSP00000505532.1:p.Glu511Val HLA-B*45:01 10 3 8 AERMGFTVVT AERMGFTEVT NetMHC 22.44 42.62 1.899 NetMHC 0.03 0.06 149 0.302 1233 0.348 139 0.007 131.835 0.0 214.664 219.26 1.021 0.33 0.462 0.18812804 0.034368556 0.014715277 0.0029568933 0.2832114603370428 0.3730203146114945 0.5144309887378682 0.5231498188416924 0.7930434782607136 0.7725815217389993 226.68944851048937 303.3089523399954 0.5342499999999998 0.6408749999999996 86.69 36.58 0.3899999999999999 0.1699999999999999 42.62 22.44 0.06 0.03 211.83 126.02 0.35 0.21 54.92 23.99 0.08 0.04 0.346 0.407 0.32 0.26 605.05 409.85 0.6 0.4 626.17 599.36 2.4 2.2 398.04 385.42 1.3 1.3 63.ADAR.ENST00000680270.1.missense.511E/V NA NA None 1.6142857142857143 1.6142857142857143 False False False 0 False 0 @@ -106,7 +106,7 @@ chr14 55180753 55180754 G A ENST00000395425.6 1 842 False False protein_coding N chr14 55180753 55180754 G A ENST00000557645.5 3 234 False False protein_coding None ENSG00000126787 missense S/L 202 DLGAP5 ENST00000557645.5:c.605C>T ENSP00000451747.1:p.Ser202Leu HLA-B*82:02 11 8 4 MPTLLRMTRSA MPTSLRMTRSA MHCnuggetsI 210.05 191.34 0.911 NetMHCcons 0.15 0.15 271 0.24 825 0.224 156 0.0 53.642 1.923 466.68 434.98 0.932 0.73 0.67 7.17593e-05 8.224103e-05 0.00040481574 0.00051308016 0.3099518930539489 0.1681721147033386 0.0201123979959788 0.0080984483800818 11.6303260869565 27.61739130434782 14488.839991139945 22331.23201886816 2.292 6.517874999999999 191.34 210.05 0.67 0.73 NA NA NA NA 434.98 437.34 0.15 0.15 4133.23 4246.7 0.49 0.51 0.0513 0.0278 1.8 3.2 371.82 466.68 0.3 0.5 NA NA NA NA NA NA NA NA 745.DLGAP5.ENST00000557645.5.missense.202S/L NA NA None -0.42857142857142855 0.6571428571428571 False False False 0 False 0 chr13 113425167 113425168 G T ENST00000356501.8 1 272 False False protein_coding None ENSG00000153531 missense H/N 138 ADPRHL1 ENST00000356501.8:c.412C>A ENSP00000348894.4:p.His138Asn HLA-B*45:01 9 4 6 AEYQENWFY AEYQEHWFY NetMHCcons 241.2 149.84 0.621 NetMHCpanEL 0.31 0.29 58 0.517 24 0.917 95 0.0 2.743 0.883 506.405 500.045 0.987 0.931 0.847 0.13578571 0.058636986 0.017652843 0.0065044286 0.6844735443592072 0.5793410204350948 0.57062616535875 0.4838669145450174 0.6736956521738335 0.8561956521737955 774.1896174414004 756.0645855349429 1.0208749999999989 1.0052499999999989 9995.59 9293.69 10.42 9.75 351.29 507.43 0.51 0.73 149.84 241.2 0.43 0.59 808.24 975.54 0.53 0.61 0.384 0.357 0.29 0.31 437.34 409.85 1.2 1.1 457.31 464.74 1.6 1.6 542.78 505.38 2.0 1.8 722.ADPRHL1.ENST00000356501.8.missense.138H/N NA NA None -1.6000000000000003 -1.6000000000000003 False False False 0 False 0 chr10 125859825 125859826 G C ENST00000284690.4 1 743 True True protein_coding None ENSG00000089876 missense P/R 209 DHX32 ENST00000284690.4:c.626C>G ENSP00000284690.3:p.Pro209Arg HLA-C*06:02 9 7 3 ARRELKLII ARPELKLII SMMPMBEC 50.53 138.86 2.748 NetMHCpan 0.19 0.08 95 1.0 518 0.998 56 0.0 53.951 42.576 507.74 530.85 1.046 0.462 0.925 0.82796586 0.020647837 0.14819327 0.025092287 0.8263296112418175 0.1943617225624621 0.9675906706909142 0.6734468673941649 0.0225815217391556 0.484456521739105 52.70924635111686 82.61803545008166 0.06825 0.222125 13734.02 1342.58 25.87 4.99 2699.29 1165.34 0.85 0.4 912.75 326.55 1.2 0.44 342.29 802.42 0.08 0.19 0.597 0.252 0.03 0.22 719.41 688.93 1.0 0.9 96.79 53.43 1.5 0.9 138.86 50.53 2.0 0.9 588.DHX32.ENST00000284690.4.missense.209P/R 0.9342657 0.8979587 None 0.6714285714285715 0.6714285714285715 False False False 0 False 0 -chrX 41344254 41344255 G C ENST00000644109.1 NA 716 False False protein_coding None ENSG00000215301 missense R/T 293 DDX3X ENST00000644109.1:c.878G>C ENSP00000494952.1:p.Arg293Thr HLA-C*06:02 9 2 8 RKFSYRSTV RKFSYRSRV MHCnuggetsI 50.61 127.72 2.524 NetMHC 0.13 0.24 58 0.966 1381 0.999 72 0.014 158.794 1.432 513.09 906.662 1.767 0.635 1.6 0.0014739039 0.0026497305 0.024830949 0.032398544 0.3225912917405367 0.5575715699233115 0.2423024573201791 0.6978436744654398 1.60233695652164 0.4409239130434628 898.0131376664011 276.0651809792311 2.5710000000000006 0.9857499999999996 127.72 50.61 1.08 0.52 656.99 322.65 0.24 0.13 1354.76 592.1 1.6 0.75 853.84 610.55 0.21 0.14 0.162 0.204 0.34 0.27 932.72 711.66 1.6 1.0 3182.8 2222.34 19.0 16.0 915.31 434.08 8.6 5.1 1066.DDX3X.ENST00000644109.1.missense.293R/T 0.98557866 0.9932834 None -0.15714285714285722 -0.15714285714285722 False False False 0 False 0 +chrX 41344254 41344255 G C ENST00000399959.7 1 661 False False protein_coding None ENSG00000215301 missense R/T 293 DDX3X ENST00000399959.7:c.878G>C ENSP00000382840.3:p.Arg293Thr HLA-C*06:02 9 2 8 RKFSYRSTV RKFSYRSRV MHCnuggetsI 50.61 127.72 2.524 NetMHC 0.13 0.24 58 0.966 1381 0.999 72 0.014 158.794 0.735 513.09 906.662 1.767 0.635 1.6 0.0014739039 0.0026497305 0.024830949 0.032398544 0.3225912917405367 0.5575715699233115 0.2423024573201791 0.6978436744654398 1.60233695652164 0.4409239130434628 898.0131376664011 276.0651809792311 2.5710000000000006 0.9857499999999996 127.72 50.61 1.08 0.52 656.99 322.65 0.24 0.13 1354.76 592.1 1.6 0.75 853.84 610.55 0.21 0.14 0.162 0.204 0.34 0.27 932.72 711.66 1.6 1.0 3182.8 2222.34 19.0 16.0 915.31 434.08 8.6 5.1 1051.DDX3X.ENST00000399959.7.missense.293R/T 0.98557866 0.9932834 None -0.15714285714285722 -0.15714285714285722 False False False 0 False 0 chr6 157133135 157133136 G C ENST00000346085.10 1 2332 False False protein_coding None ENSG00000049618 missense G/A 910 ARID1B ENST00000346085.10:c.2729G>C ENSP00000344546.5:p.Gly910Ala HLA-B*82:02 10 2 9 SPGGQMHAAI SPGGQMHAGI MHCnuggetsI 47.6 232.71 4.889 MHCnuggetsI 0.14 0.8 109 1.0 163 1.0 98 0.01 39.757 0.097 514.41 1304.42 2.536 0.3 0.7 0.0016947056 0.0032140964 0.004044852 0.013937958 0.005893466877751 0.0170579199620988 0.0235474082470676 0.0591425936902998 10.23198369565216 4.391929347826036 4054.8303502799113 1574.991454617033 0.6574999999999991 0.3397499999999996 232.71 47.6 0.8 0.1399999999999999 NA NA NA NA 1304.42 514.41 0.83 0.14 3954.14 1938.1 0.46 0.18 0.122 0.144 0.64 0.52 659.75 352.24 0.7 0.3 NA NA NA NA NA NA NA NA 374.ARID1B.ENST00000346085.10.missense.910G/A NA NA None 0.4142857142857142 0.4142857142857142 False False False 0 False 0 chr6 157133135 157133136 G C ENST00000350026.10 1 2236 False False protein_coding None ENSG00000049618 missense G/A 814 ARID1B ENST00000350026.10:c.2441G>C ENSP00000055163.7:p.Gly814Ala HLA-B*82:02 10 2 9 SPGGQMHAAI SPGGQMHAGI MHCnuggetsI 47.6 232.71 4.889 MHCnuggetsI 0.14 0.8 109 1.0 163 1.0 98 0.01 39.757 0.0 514.41 1304.42 2.536 0.3 0.7 0.0016947056 0.0032140964 0.004044852 0.013937958 0.005893466877751 0.0170579199620988 0.0235474082470676 0.0591425936902998 10.23198369565216 4.391929347826036 4054.8303502799113 1574.991454617033 0.6574999999999991 0.3397499999999996 232.71 47.6 0.8 0.1399999999999999 NA NA NA NA 1304.42 514.41 0.83 0.14 3954.14 1938.1 0.46 0.18 0.122 0.144 0.64 0.52 659.75 352.24 0.7 0.3 NA NA NA NA NA NA NA NA 375.ARID1B.ENST00000350026.10.missense.814G/A NA NA None 0.4142857142857142 0.4142857142857142 False False False 0 False 0 chr6 157133135 157133136 G C ENST00000414678.7 5 1758 False False protein_coding None ENSG00000049618 missense G/A 283 ARID1B ENST00000414678.7:c.848G>C ENSP00000412835.2:p.Gly283Ala HLA-B*82:02 10 2 9 SPGGQMHAAI SPGGQMHAGI MHCnuggetsI 47.6 232.71 4.889 MHCnuggetsI 0.14 0.8 109 1.0 163 1.0 98 0.01 39.757 5.811 514.41 1304.42 2.536 0.3 0.7 0.0016947056 0.0032140964 0.004044852 0.013937958 0.005893466877751 0.0170579199620988 0.0235474082470676 0.0591425936902998 10.23198369565216 4.391929347826036 4054.8303502799113 1574.991454617033 0.6574999999999991 0.3397499999999996 232.71 47.6 0.8 0.1399999999999999 NA NA NA NA 1304.42 514.41 0.83 0.14 3954.14 1938.1 0.46 0.18 0.122 0.144 0.64 0.52 659.75 352.24 0.7 0.3 NA NA NA NA NA NA NA NA 376.ARID1B.ENST00000414678.7.missense.283G/A NA NA None 0.4142857142857142 0.4142857142857142 False False False 0 False 0 @@ -162,7 +162,7 @@ chr6 30986467 30986468 T C ENST00000376296.3 1 566 True True protein_coding None chr7 82916602 82916603 C A ENST00000333891.14 2 5142 True True protein_coding None ENSG00000186472 missense D/Y 3795 PCLO ENST00000333891.14:c.11383G>T ENSP00000334319.8:p.Asp3795Tyr HLA-C*06:02 9 7 3 EIYAKLRYL EIDAKLRYL NetMHC 253.06 2614.6 10.332 NetMHC 0.11 0.83 266 0.222 35 0.171 154 0.0 4.482 0.037 700.485 2134.795 3.048 1.333 3.9 0.0015162512 0.241527 0.006181161 0.035120487 0.1850216845050454 0.4026004653424024 0.3016652265967385 0.5523410073511136 1.3596467391303406 0.7129891304346785 399.2171466765197 299.33526054910965 1.3631250000000004 1.067 3579.32 2631.0 9.36 7.61 2614.6 253.06 0.83 0.11 7860.43 1354.76 7.4 1.6 14184.3 1063.05 4.5 0.25 0.0254 0.274 1.6 0.19 1654.99 2579.01 3.6 6.9 342.62 337.92 4.2 4.1 417.42 317.37 4.9 3.9 398.PCLO.ENST00000333891.14.missense.3795D/Y 0.9904023 0.9866387 None -0.2285714285714285 -0.12857142857142853 True False False 0 False 0 chr7 82916602 82916603 C A ENST00000423517.6 5 4935 False False protein_coding None ENSG00000186472 missense D/Y 3795 PCLO ENST00000423517.6:c.11383G>T ENSP00000388393.2:p.Asp3795Tyr HLA-C*06:02 9 7 3 EIYAKLRYL EIDAKLRYL NetMHC 253.06 2614.6 10.332 NetMHC 0.11 0.83 266 0.222 35 0.171 154 0.0 4.482 2.087 700.485 2134.795 3.048 1.333 3.9 0.0015162512 0.241527 0.006181161 0.035120487 0.1850216845050454 0.4026004653424024 0.3016652265967385 0.5523410073511136 1.3596467391303406 0.7129891304346785 399.2171466765197 299.33526054910965 1.3631250000000004 1.067 3579.32 2631.0 9.36 7.61 2614.6 253.06 0.83 0.11 7860.43 1354.76 7.4 1.6 14184.3 1063.05 4.5 0.25 0.0254 0.274 1.6 0.19 1654.99 2579.01 3.6 6.9 342.62 337.92 4.2 4.1 417.42 317.37 4.9 3.9 399.PCLO.ENST00000423517.6.missense.3795D/Y 0.9904023 0.9866387 None -0.2285714285714285 -0.12857142857142853 True False False 0 False 0 chr7 82916602 82916603 C A ENST00000437081.1 1 1217 False False protein_coding None ENSG00000186472 missense D/Y 515 PCLO ENST00000437081.1:c.1543G>T ENSP00000393760.1:p.Asp515Tyr HLA-C*06:02 9 7 3 EIYAKLRYL EIDAKLRYL NetMHC 253.06 2614.6 10.332 NetMHC 0.11 0.83 266 0.222 35 0.171 154 0.0 4.482 0.832 700.485 2134.795 3.048 1.333 3.9 0.0015162512 0.241527 0.006181161 0.035120487 0.1850216845050454 0.4026004653424024 0.3016652265967385 0.5523410073511136 1.3596467391303406 0.7129891304346785 399.2171466765197 299.33526054910965 1.3631250000000004 1.067 3579.32 2631.0 9.36 7.61 2614.6 253.06 0.83 0.11 7860.43 1354.76 7.4 1.6 14184.3 1063.05 4.5 0.25 0.0254 0.274 1.6 0.19 1654.99 2579.01 3.6 6.9 342.62 337.92 4.2 4.1 417.42 317.37 4.9 3.9 400.PCLO.ENST00000437081.1.missense.515D/Y 0.9904023 0.9866387 None -0.2285714285714285 -0.12857142857142853 True False False 0 False 0 -chr22 41524890 41524891 G C ENST00000396512.3 5 805 False False protein_coding None ENSG00000100412 missense E/Q 535 ACO2 ENST00000396512.3:c.1603G>C ENSP00000379769.3:p.Glu535Gln HLA-A*29:02 10 4 7 TLKFNPQTDY TLKFNPETDY NetMHC 259.62 591.85 2.28 NetMHCpanEL 0.29 0.45 116 0.216 1640 0.238 78 0.0 119.616 0.112 710.204 789.7 1.112 1.778 1.939 0.16227476 0.14100324 0.58836687 0.62671816 0.1905169300734996 0.2488580346107483 0.210017893145985 0.2754316372523164 1.7785054347825593 1.4566304347825252 671.3394769299683 574.5886456045152 1.4302499999999998 1.3285 5574.19 5319.07 7.26 3.76 591.85 259.62 1.3 0.73 534.26 520.0 2.1 2.1 750.92 366.9 0.81 0.51 0.244 0.382 0.45 0.29 11355.63 9550.53 13.0 9.0 828.48 845.82 3.3 3.4 1187.22 1212.08 4.2 4.2 1015.ACO2.ENST00000396512.3.missense.535E/Q NA NA None -1.6142857142857143 -0.942857142857143 False False False 0 False 1 +chr22 41524890 41524891 G C ENST00000216254.9 1 780 True True protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.9:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-A*29:02 10 4 7 TLKFNPQTDY TLKFNPETDY NetMHC 259.62 591.85 2.28 NetMHCpanEL 0.29 0.45 116 0.216 1640 0.238 78 0.0 119.616 101.95 710.204 789.7 1.112 1.778 1.939 0.16227476 0.14100324 0.58836687 0.62671816 0.1905169300734996 0.2488580346107483 0.210017893145985 0.2754316372523164 1.7785054347825593 1.4566304347825252 671.3394769299683 574.5886456045152 1.4302499999999998 1.3285 5574.19 5319.07 7.26 3.76 591.85 259.62 1.3 0.73 534.26 520.0 2.1 2.1 750.92 366.9 0.81 0.51 0.244 0.382 0.45 0.29 11355.63 9550.53 13.0 9.0 828.48 845.82 3.3 3.4 1187.22 1212.08 4.2 4.2 1014.ACO2.ENST00000216254.9.missense.510E/Q NA NA None -1.6142857142857143 -0.942857142857143 False False False 0 False 1 chr19 57397065 57397066 G T ENST00000366197.9 1 533 False False protein_coding None ENSG00000188785 missense D/Y 12 ZNF548 ENST00000366197.9:c.34G>T ENSP00000379482.3:p.Asp12Tyr HLA-A*29:02 10 1 10 LTEGRVVFEY LTEGRVVFED MHCflurry 207.229 29437.384 142.053 MHCflurry 0.337 36.486 222 0.468 127 0.378 290 0.0 13.433 0.286 735.375 38231.155 51.989 1.135 69.0 0.0016515435 0.32100913 0.15368392 0.90009224 0.0137453522183932 0.5738650038838387 0.0036018549871392 0.7637404525442404 99.28660326086955 0.3367119565217251 29437.38390623267 207.22860170748007 36.485875 0.7735 6006.63 3997.26 96.56 0.8699999999999999 35203.22 722.1 54.0 1.4 36534.22 207.3 78.0 1.4 39928.09 281.78 67.0 0.43 1e-06 0.12 94.0 0.85 40270.83 4196.68 41.0 2.5 40204.99 748.65 51.0 3.0 86403.23 894.4 71.0 3.5 957.ZNF548.ENST00000366197.9.missense.12D/Y NA NA None 0.21428571428571425 0.4428571428571428 False False False 0 False 0 chr19 57397065 57397066 G T ENST00000596617.5 4 106 False False protein_coding None ENSG00000269533 missense D/Y 24 ENSG00000269533 ENST00000596617.5:c.70G>T ENSP00000471870.1:p.Asp24Tyr HLA-C*06:02 9 5 5 VVFEYVAIY VVFEDVAIY SMM 44.85 99.73 2.224 NetMHC 0.2 0.69 222 0.468 127 0.378 290 0.0 NA 0.0 740.014 1571.65 2.124 1.25 1.966 0.01184608 0.052571036 0.06176595 0.098331794 0.314181812107563 0.4424116834998131 0.2362479475926168 0.3938387961334018 1.6326630434781606 1.0730434782607148 901.263968908944 669.6986240263325 2.5910000000000006 2.0585000000000013 10483.91 14275.28 20.5 26.8 2190.18 539.22 0.69 0.2 4600.95 1709.59 4.4 1.9 8625.46 5229.66 2.3 1.4 0.0283 0.0516 1.5 0.96 953.12 810.33 1.6 1.2 99.73 44.85 1.5 0.8 157.97 77.91 2.3 1.3 961.ENSG00000269533.ENST00000596617.5.missense.24D/Y 0.98675114 0.9911419 None 1.0285714285714287 1.8142857142857145 False False False 0 False 0 chr5 115130597 115130604 ACTAACTG A ENST00000282369.7 1 728 False False protein_coding None ENSG00000152503 FS AVS/X 607-609 TRIM36 ENST00000282369.7:c.1820_1826del ENSP00000282369.3:p.Ala607ValfsTer27 HLA-B*82:02 10 25 NA MPVLILHNHL NA NetMHCcons 356.07 NA NA NetMHCcons 0.06 NA 88 0.92 0 0.0 105 0.0 1.136 0.0 740.19 NA NA 0.26 NA NA 0.0050378926 NA 0.02894641 NA 0.3429921963252127 NA 0.2239884375655981 NA 1.6983695652173054 NA 1074.9098862910848 NA 0.2603749999999996 NA 1800.36 NA 3.32 NA NA NA NA NA 356.07 NA 0.06 NA 740.19 NA 0.06 NA 0.238 NA 0.24 NA 363.86 NA 0.3 NA NA NA NA NA NA NA NA 298.TRIM36.ENST00000282369.7.FS.607-609ACTAACTG/A NA NA None 0.8571428571428574 1.9142857142857146 False False False 0 False 0 @@ -488,7 +488,7 @@ chr8 132141242 132141243 C G ENST00000521134.6 2 752 False False protein_coding chr2 175093191 175093192 C G ENST00000264110.7 1 505 True True protein_coding None ENSG00000115966 missense D/H 352 ATF2 ENST00000264110.7:c.1054G>C ENSP00000264110.2:p.Asp352His HLA-B*82:02 10 8 3 DPHEKRRKFL DPDEKRRKFL PickPocket 1170.65 902.93 0.771 NetMHCpanEL 0.96 0.32 293 0.461 878 0.445 173 0.0 100.906 13.081 3133.53 4237.88 1.352 2.2 1.8 0.00026467064 0.00013510052 0.003302831 0.0014707202 0.078919521998614 0.0633547746110707 0.0232564562344311 0.0097485126412386 10.23198369565216 24.57923913043477 5360.250743221761 12573.186567536814 0.8001249999999993 1.8493749999999995 4237.88 2689.91 5.75 4.279999999999999 NA NA NA NA 2607.06 3133.53 1.8 2.2 11280.32 13228.17 2.6 3.4 0.206 0.092 0.32 0.96 902.93 1170.65 1.2 1.7 NA NA NA NA NA NA NA NA 161.ATF2.ENST00000264110.7.missense.352D/H NA NA None -1.9571428571428566 -1.9571428571428566 False False False 0 False 0 chr2 175093191 175093192 C G ENST00000435004.6 5 265 False False protein_coding None ENSG00000115966 missense D/H 181 ATF2 ENST00000435004.6:c.541G>C ENSP00000406995.2:p.Asp181His HLA-B*82:02 10 8 3 DPHEKRRKFL DPDEKRRKFL PickPocket 1170.65 902.93 0.771 NetMHCpanEL 0.96 0.32 293 0.461 878 0.445 173 0.0 100.906 0.209 3133.53 4237.88 1.352 2.2 1.8 0.00026467064 0.00013510052 0.003302831 0.0014707202 0.078919521998614 0.0633547746110707 0.0232564562344311 0.0097485126412386 10.23198369565216 24.57923913043477 5360.250743221761 12573.186567536814 0.8001249999999993 1.8493749999999995 4237.88 2689.91 5.75 4.279999999999999 NA NA NA NA 2607.06 3133.53 1.8 2.2 11280.32 13228.17 2.6 3.4 0.206 0.092 0.32 0.96 902.93 1170.65 1.2 1.7 NA NA NA NA NA NA NA NA 170.ATF2.ENST00000435004.6.missense.181D/H NA NA None -1.9571428571428566 -1.9571428571428566 False False False 0 False 0 chr17 82961144 82961145 G C ENST00000576599.5 2 250 False False protein_coding None ENSG00000175711 missense L/V 102 B3GNTL1 ENST00000576599.5:c.304C>G ENSP00000461127.1:p.Leu102Val HLA-A*29:02 9 3 7 LFFYEHVRK LFFYEHLRK PickPocket 953.12 743.14 0.78 PickPocket 0.8 0.5 113 0.221 81 0.235 69 0.0 10.001 0.497 3140.125 974.35 0.31 4.55 2.25 0.004163932 0.0018495325 0.08613348 0.033944033 0.0378223485313355 0.1747747836634516 0.0091951159613904 0.0129767480139807 24.57923913043477 18.61798913043478 12174.045403925706 14007.166266033424 6.140374999999998 7.078749999999999 3917.37 4279.31 0.83 1.06 504.14 2782.73 1.2 2.9 1062.03 4830.5 2.9 6.2 1067.84 2522.4 1.2 1.8 0.0415 0.0237 1.6 2.1 743.14 953.12 0.5 0.8 886.67 3497.52 3.3 7.9 774.41 2471.55 3.0 6.2 901.B3GNTL1.ENST00000576599.5.missense.102L/V NA NA None -1.342857142857143 0.7999999999999997 False False False 0 False 0 -chr22 50177151 50177152 C T ENST00000395842.3 2 677 True True protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.3:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-A*29:02 10 10 1 FTRLTSELNF STRLTSELNF SMM 1419.97 2100.29 1.479 NetMHCpan 2.4 4.0 275 0.996 124 1.0 127 0.0 10.842 8.461 3159.04 6347.474 2.009 4.155 6.2 0.01894618 0.035588954 0.26986662 0.51099724 0.1887423131847754 0.2554535372182727 0.0262121736602738 0.0459900009406953 9.15535326086956 5.554945652173885 7048.02783796301 4932.456310615854 4.107874999999998 3.390374999999999 5646.92 5428.5 9.33 4.81 7665.57 2612.2 6.0 2.8 3975.68 1663.96 5.3 3.5 7499.69 3705.88 4.0 2.4 0.00766 0.00915 3.6 3.3 12249.09 10414.04 14.0 12.0 2100.29 1419.97 6.4 4.9 2751.25 1460.6 7.7 5.0 1027.PANX2.ENST00000395842.3.missense.147S/F NA NA None 0.27142857142857135 0.27142857142857135 False False False 0 False 0 +chr22 50177151 50177152 C T ENST00000159647.9 1 643 False False protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000159647.9:c.440C>T ENSP00000159647.5:p.Ser147Phe HLA-A*29:02 10 10 1 FTRLTSELNF STRLTSELNF SMM 1419.97 2100.29 1.479 NetMHCpan 2.4 4.0 275 0.996 124 1.0 127 0.0 10.842 0.0 3159.04 6347.474 2.009 4.155 6.2 0.01894618 0.035588954 0.26986662 0.51099724 0.1887423131847754 0.2554535372182727 0.0262121736602738 0.0459900009406953 9.15535326086956 5.554945652173885 7048.02783796301 4932.456310615854 4.107874999999998 3.390374999999999 5646.92 5428.5 9.33 4.81 7665.57 2612.2 6.0 2.8 3975.68 1663.96 5.3 3.5 7499.69 3705.88 4.0 2.4 0.00766 0.00915 3.6 3.3 12249.09 10414.04 14.0 12.0 2100.29 1419.97 6.4 4.9 2751.25 1460.6 7.7 5.0 1026.PANX2.ENST00000159647.9.missense.147S/F NA NA None 0.27142857142857135 0.27142857142857135 False False False 0 False 0 chr11 46728135 46728136 T C ENST00000311907.10 1 622 True True protein_coding None ENSG00000180210 missense V/A 424 F2 ENST00000311907.10:c.1271T>C ENSP00000308541.5:p.Val424Ala HLA-C*06:02 11 11 1 ARIGKHSRTRY VRIGKHSRTRY MHCnuggetsI 30.04 27.66 0.921 MHCnuggetsI 0.32 0.3 56 0.357 1 1.0 72 0.0 0.048 0.0 3160.555 2877.754 0.911 2.903 3.15 0.0019336286 0.0011280824 0.0072130826 0.003974293 0.1075032541994005 0.1055469447746872 0.0601682420187242 0.0915443737069793 4.329592391304317 3.1065489130433974 2148.718098413948 1337.40779081582 4.8526250000000015 3.4520000000000013 27.66 30.04 0.3 0.32 25065.53 29276.01 14.0 19.0 1183.39 2635.42 1.2 2.5 11964.33 15256.68 3.6 5.0 0.0289 0.0285 1.5 1.5 3606.79 3685.69 2.7 2.7 NA NA NA NA NA NA NA NA 641.F2.ENST00000311907.10.missense.424V/A NA NA None -2.6999999999999997 -0.9285714285714286 False False False 0 False 0 chr11 46728135 46728136 T C ENST00000530231.5 5 583 False False protein_coding None ENSG00000180210 missense V/A 424 F2 ENST00000530231.5:c.1271T>C ENSP00000433907.1:p.Val424Ala HLA-C*06:02 11 11 1 ARIGKHSRTRY VRIGKHSRTRY MHCnuggetsI 30.04 27.66 0.921 MHCnuggetsI 0.32 0.3 56 0.357 1 1.0 72 0.0 0.048 0.048 3160.555 2877.754 0.911 2.903 3.15 0.0019336286 0.0011280824 0.0072130826 0.003974293 0.1075032541994005 0.1055469447746872 0.0601682420187242 0.0915443737069793 4.329592391304317 3.1065489130433974 2148.718098413948 1337.40779081582 4.8526250000000015 3.4520000000000013 27.66 30.04 0.3 0.32 25065.53 29276.01 14.0 19.0 1183.39 2635.42 1.2 2.5 11964.33 15256.68 3.6 5.0 0.0289 0.0285 1.5 1.5 3606.79 3685.69 2.7 2.7 NA NA NA NA NA NA NA NA 642.F2.ENST00000530231.5.missense.424V/A NA NA None -2.6999999999999997 -0.9285714285714286 False False False 0 False 0 chr6 29174125 29174126 C T ENST00000377167.3 NA 312 False False protein_coding None ENSG00000204700 missense T/I 164 OR2J2 ENST00000377167.3:c.491C>T ENSP00000366372.2:p.Thr164Ile HLA-A*29:02 10 2 9 ISALHSSFIF ISALHSSFTF SMMPMBEC 565.63 699.09 1.236 NetMHCpan 1.8 1.9 282 0.277 0 0.0 129 0.0 0.037 0.0 3172.77 2790.625 0.88 4.248 3.518 0.016051257 0.021803664 0.45604867 0.555117 0.2121261120773852 0.1142123515019193 0.0347221663783693 0.0156089762193929 7.147065217391287 15.160951086956516 5694.155899303447 9263.566125240915 3.635499999999999 4.896999999999999 5438.05 5715.36 4.93 12.39 3012.19 3871.17 3.0 3.6 1525.99 1718.86 3.4 3.5 2569.06 2474.37 1.9 1.8 0.00619 0.00307 4.0 5.6 9972.95 9865.62 9.6 9.5 679.64 738.38 2.8 3.0 699.09 565.63 2.9 2.3 335.OR2J2.ENST00000377167.3.missense.164T/I NA NA None 1.2999999999999996 1.2999999999999996 False False False 0 False 0 @@ -548,7 +548,7 @@ chr5 141123692 141123693 G C ENST00000194152.4 NA 795 True True protein_coding N chr1 154590262 154590263 T A ENST00000648311.1 NA 931 False False protein_coding None ENSG00000160710 missense E/V 511 ADAR ENST00000648311.1:c.1532A>T ENSP00000498137.1:p.Glu511Val HLA-C*06:02 9 5 5 MGFTVVTPV MGFTEVTPV MHCflurry 368.392 520.631 1.413 NetMHCpan 0.55 0.78 149 0.302 1233 0.348 139 0.007 131.835 0.922 3814.315 2744.21 0.719 5.4 4.75 0.0010492645 0.0018215334 0.087530375 0.13906208 0.0047116387577261 0.0123475530999712 0.1499147673227826 0.2022537495507732 2.231603260869477 1.8201630434782032 520.6306812098449 368.3917089290788 1.6970000000000007 1.2680000000000002 4113.74 6397.14 10.3 13.98 11159.53 12908.06 4.1 4.8 8387.64 8119.76 7.9 7.7 3365.81 2473.94 0.78 0.55 0.00793 0.0109 3.2 2.7 2122.61 2314.53 5.4 6.0 1670.36 4632.44 14.0 23.0 1316.95 2996.19 12.0 19.0 56.ADAR.ENST00000648311.1.missense.511E/V 0.9913146 0.99111134 None 1.7714285714285718 1.7714285714285718 False False False 0 False 0 chr1 154590262 154590263 T A ENST00000649022.2 NA 931 False False protein_coding None ENSG00000160710 missense E/V 511 ADAR ENST00000649022.2:c.1532A>T ENSP00000496896.2:p.Glu511Val HLA-C*06:02 9 5 5 MGFTVVTPV MGFTEVTPV MHCflurry 368.392 520.631 1.413 NetMHCpan 0.55 0.78 149 0.302 1233 0.348 139 0.007 131.835 1.143 3814.315 2744.21 0.719 5.4 4.75 0.0010492645 0.0018215334 0.087530375 0.13906208 0.0047116387577261 0.0123475530999712 0.1499147673227826 0.2022537495507732 2.231603260869477 1.8201630434782032 520.6306812098449 368.3917089290788 1.6970000000000007 1.2680000000000002 4113.74 6397.14 10.3 13.98 11159.53 12908.06 4.1 4.8 8387.64 8119.76 7.9 7.7 3365.81 2473.94 0.78 0.55 0.00793 0.0109 3.2 2.7 2122.61 2314.53 5.4 6.0 1670.36 4632.44 14.0 23.0 1316.95 2996.19 12.0 19.0 57.ADAR.ENST00000649022.2.missense.511E/V 0.9913146 0.99111134 None 1.7714285714285718 1.7714285714285718 False False False 0 False 0 chr16 2295600 2295601 C G ENST00000382381.7 1 1646 False False protein_coding None ENSG00000167972 missense E/D 743 ABCA3 ENST00000382381.7:c.2229G>C ENSP00000371818.3:p.Glu743Asp HLA-A*29:02 11 6 6 FILPRDSTHRF FILPRESTHRF SMMPMBEC 307.52 287.65 0.935 MHCnuggetsI 0.28 0.34 187 0.578 86 0.628 164 0.0 6.12 0.799 3817.5 4138.87 1.084 1.537 1.894 0.19970262 0.1542864 0.2714677 0.27153388 0.679052647203207 0.6370592042803764 0.4143291239568756 0.5453044360520288 1.0214402173911594 0.726657608695561 1452.6860911889903 724.0279614251721 1.987125 1.4738749999999996 2296.16 2006.91 0.3399999999999999 0.2799999999999999 8500.57 7736.98 6.5 6.0 704.01 531.38 1.6 1.3 5981.58 5628.09 3.3 3.2 0.0348 0.0425 1.8 1.6 9447.76 8664.37 8.1 7.0 9112.34 9899.88 29.0 32.0 287.65 307.52 1.3 1.4 831.ABCA3.ENST00000382381.7.missense.743E/D NA NA None -2.057142857142857 0.09999999999999999 False False False 0 False 0 -chrX 78015862 78015863 G C ENST00000689767.1 NA 1531 False False protein_coding None ENSG00000165240 missense D/H 901 ATP7A ENST00000689767.1:c.2701G>C ENSP00000509406.1:p.Asp901His HLA-B*45:01 11 11 1 HESLITGEAMP DESLITGEAMP MHCflurry 201.827 3158.632 15.65 MHCflurry 0.492 1.807 55 0.982 41 0.951 58 0.0 5.153 0.071 3844.075 7591.76 1.975 4.3 6.3 0.002986167 0.06420861 0.0016472809 0.022799084 0.1881183707737364 0.2427395009435713 0.0553279158924534 0.5068460990908745 4.657581521739076 0.8065217391303037 3158.631559546669 201.82722289936615 1.8069999999999984 0.4923749999999998 32240.46 16143.44 52.370000000000005 17.130000000000003 27397.27 18023.08 21.0 13.0 9972.95 2858.2 5.8 3.1 10543.75 4338.19 3.9 1.9 0.0265 0.0646 2.2 1.4 5210.57 3932.89 6.8 5.5 3035.92 3042.92 7.3 7.3 3440.65 3755.26 8.1 8.6 1102.ATP7A.ENST00000689767.1.missense.901D/H NA NA None 0.28571428571428564 1.0571428571428572 False False True 0 False 0 +chrX 78015862 78015863 G C ENST00000341514.11 1 1500 True True protein_coding None ENSG00000165240 missense D/H 870 ATP7A ENST00000341514.11:c.2608G>C ENSP00000345728.6:p.Asp870His HLA-B*45:01 11 11 1 HESLITGEAMP DESLITGEAMP MHCflurry 201.827 3158.632 15.65 MHCflurry 0.492 1.807 55 0.982 41 0.951 58 0.0 5.153 1.293 3844.075 7591.76 1.975 4.3 6.3 0.002986167 0.06420861 0.0016472809 0.022799084 0.1881183707737364 0.2427395009435713 0.0553279158924534 0.5068460990908745 4.657581521739076 0.8065217391303037 3158.631559546669 201.82722289936615 1.8069999999999984 0.4923749999999998 32240.46 16143.44 52.370000000000005 17.130000000000003 27397.27 18023.08 21.0 13.0 9972.95 2858.2 5.8 3.1 10543.75 4338.19 3.9 1.9 0.0265 0.0646 2.2 1.4 5210.57 3932.89 6.8 5.5 3035.92 3042.92 7.3 7.3 3440.65 3755.26 8.1 8.6 1092.ATP7A.ENST00000341514.11.missense.870D/H NA NA None 0.28571428571428564 1.0571428571428572 False False True 0 False 0 chrX 78015862 78015863 G C ENST00000343533.10 5 1510 False False protein_coding None ENSG00000165240 missense D/H 880 ATP7A ENST00000343533.10:c.2638G>C ENSP00000343026.6:p.Asp880His HLA-B*45:01 11 11 1 HESLITGEAMP DESLITGEAMP MHCflurry 201.827 3158.632 15.65 MHCflurry 0.492 1.807 55 0.982 41 0.951 58 0.0 5.153 0.114 3844.075 7591.76 1.975 4.3 6.3 0.002986167 0.06420861 0.0016472809 0.022799084 0.1881183707737364 0.2427395009435713 0.0553279158924534 0.5068460990908745 4.657581521739076 0.8065217391303037 3158.631559546669 201.82722289936615 1.8069999999999984 0.4923749999999998 32240.46 16143.44 52.370000000000005 17.130000000000003 27397.27 18023.08 21.0 13.0 9972.95 2858.2 5.8 3.1 10543.75 4338.19 3.9 1.9 0.0265 0.0646 2.2 1.4 5210.57 3932.89 6.8 5.5 3035.92 3042.92 7.3 7.3 3440.65 3755.26 8.1 8.6 1093.ATP7A.ENST00000343533.10.missense.880D/H NA NA None 0.28571428571428564 1.0571428571428572 False False True 0 False 0 chr12 49526214 49526215 G A ENST00000553127.5 1 545 False False protein_coding None ENSG00000123352 missense R/H 533 SPATS2 ENST00000553127.5:c.1598G>A ENSP00000448228.1:p.Arg533His HLA-B*82:02 10 7 4 LPQHKPRTSQ LPQRKPRTSQ MHCnuggetsI 1499.52 1144.42 0.763 PickPocket 2.3 2.6 62 0.968 334 1.0 63 0.0 23.424 0.49 3869.58 4040.73 1.044 4.619 6.518 5.0710507e-05 0.00015302801 0.00014935333 0.00030547736 0.0130316559370839 0.0145601099429768 0.0047166629235917 0.0052358549030218 62.74467391304348 46.22467391304348 22218.12257992977 20054.02948504213 6.517874999999999 4.619124999999999 1144.42 1499.52 2.49 2.94 NA NA NA NA 4040.73 3869.58 2.6 2.5 23191.76 23965.98 13.0 13.0 0.00906 0.0105 7.1 6.5 1765.99 1550.96 2.6 2.3 NA NA NA NA NA NA NA NA 687.SPATS2.ENST00000553127.5.missense.533R/H NA NA None -2.6 -2.0714285714285716 False False False 0 False 0 chr9 113369791 113369792 G A ENST00000374183.5 1 402 True True protein_coding None ENSG00000119411 missense A/T 287 BSPRY ENST00000374183.5:c.859G>A ENSP00000363298.4:p.Ala287Thr HLA-A*29:02 9 2 8 SFQNGLHTW SFQNGLHAW MHCflurry 435.958 665.16 1.526 MHCflurry 0.433 0.623 80 0.537 0 0.0 61 0.0 0.09 0.0 3900.66 3493.92 0.896 3.9 3.45 0.037094682 0.019206127 0.11707227 0.12900913 0.6728783063590527 0.6902541965246201 0.5964804778480248 0.7032199586013494 0.6232880434781833 0.4330434782608563 665.1601314761667 435.95822071340655 1.4222499999999998 1.1698749999999998 4679.07 4503.62 1.5 1.27 5351.06 6813.46 4.5 5.4 3361.84 4084.68 5.0 5.6 3626.0 3716.64 2.4 2.4 0.118 0.155 0.86 0.7 4576.12 5324.55 12.0 14.0 2419.69 2816.83 6.1 6.8 2741.38 3459.15 6.7 7.8 543.BSPRY.ENST00000374183.5.missense.287A/T NA NA None -1.2 -0.6714285714285716 False False False 0 False 0 @@ -683,7 +683,7 @@ chr2 31366060 31366061 G C ENST00000379416.4 1 1333 True True protein_coding Non chr1 207623001 207623002 C G ENST00000367053.6 5 2039 False False protein_coding None ENSG00000203710 missense S/C 1979 CR1 ENST00000367053.6:c.5936C>G ENSP00000356020.1:p.Ser1979Cys HLA-A*29:02 10 5 6 IVGTLCGTIF IVGTLSGTIF SMMPMBEC 1283.9 1034.02 0.805 MHCflurry 3.658 3.788 277 0.285 0 0.0 217 0.009 0.135 0.0 5672.797 5757.063 1.015 6.66 5.9 0.009475927 0.01169236 0.4014642 0.5659151 0.0074701240228023 0.0121466433047316 0.0159551278381718 0.0171567955130363 15.160951086956516 13.500896739130424 6137.025439049807 5785.534612801443 3.787999999999999 3.657999999999999 5377.1 5544.36 4.26 6.619999999999999 8772.18 10046.81 6.7 7.5 4962.95 5560.06 6.1 6.5 10712.32 9324.97 5.7 5.0 0.00215 0.00122 6.6 8.7 10992.95 11112.54 12.0 12.0 1546.25 2229.87 5.1 6.7 1034.02 1283.9 3.9 4.5 87.CR1.ENST00000367053.6.missense.1979S/C NA NA 6 1.6857142857142857 1.9285714285714284 False False False 1 False 0 chrX 107601385 107601386 G T ENST00000684358.1 NA 1642 False False protein_coding None ENSG00000147234 missense S/I 981 FRMPD3 ENST00000684358.1:c.2942G>T ENSP00000507422.1:p.Ser981Ile HLA-B*82:02 10 6 5 TPKRIKLEET TPKRSKLEET MHCnuggetsI 2087.67 2183.64 1.046 MHCflurry 3.109 2.901 179 0.391 4 0.5 86 0.0 0.1 0.0 5681.68 6829.04 1.202 4.3 4.7 3.9608334e-05 0.00020931617 0.00020805384 0.0014167711 0.0257886325707659 0.2507685692980885 0.0065895812318538 0.01404970282232 37.35904891304347 16.15755434782608 16464.165495085697 17004.360261871298 2.90125 3.1086249999999995 2183.64 2087.67 3.76 3.65 NA NA NA NA 6829.04 5681.68 4.7 3.9 18044.15 17696.51 6.3 6.1 0.0215 0.0147 3.9 5.2 3529.57 3099.81 4.7 4.3 NA NA NA NA NA NA NA NA 1108.FRMPD3.ENST00000684358.1.missense.981S/I NA NA None -1.1142857142857143 -0.9 False False False 0 False 0 chr15 43149136 43149137 G C ENST00000260403.7 1 643 True True protein_coding None ENSG00000137842 missense W/C 284 TMEM62 ENST00000260403.7:c.852G>C ENSP00000260403.2:p.Trp284Cys HLA-A*29:02 11 7 5 EVGDCKDNRRY EVGDWKDNRRY SMMPMBEC 292.33 241.47 0.826 MHCflurry 1.139 0.492 75 0.96 39 1.0 83 0.0 3.179 1.366 5686.295 5253.715 0.924 5.25 4.5 0.013880888 0.009768372 0.18476665 0.31895465 0.7108080927282572 0.4154239595518447 0.6692183531442367 0.3701990865713328 0.4916032608695388 1.1393749999998448 552.8576010682153 672.92782223766 1.309125 1.4302499999999998 5517.56 5721.56 6.11 12.75 19676.67 25249.55 17.0 26.0 4989.87 5651.03 4.8 5.2 15437.01 23542.17 8.7 18.0 0.0168 0.00349 2.5 5.3 16053.81 16763.86 17.0 18.0 1354.04 1363.42 4.2 4.3 241.47 292.33 1.1 1.3 788.TMEM62.ENST00000260403.7.missense.284W/C NA NA 5 -2.6714285714285713 -1.157142857142857 True False False 1 False 0 -chr2 190982493 190982494 G C ENST00000673952.1 NA 791 False False protein_coding None ENSG00000115415 missense P/A 491 STAT1 ENST00000673952.1:c.1471C>G ENSP00000501115.1:p.Pro491Ala HLA-B*45:01 9 1 9 NLSFFLTPA NLSFFLTPP MHCnuggetsI 579.17 25262.81 43.619 MHCnuggetsI 1.41 32.02 180 0.583 1475 0.52 115 0.0 172.622 1.675 5697.765 26656.16 4.678 10.226 33.51 0.004573234 0.0028321035 0.032922383 0.0657064 0.0217496692202985 0.0117352363668032 0.0038821872844515 0.0043000028722257 99.28660326086955 62.74467391304348 28049.509252607568 24332.925950445628 20.700875 10.452499999999995 25262.81 579.17 32.02 1.41 37043.32 8015.45 35.0 5.9 38565.12 25564.3 39.0 14.0 18944.44 9521.75 7.6 3.6 9.1e-05 0.000707 28.0 12.0 16763.86 3380.08 43.0 10.0 60146.45 2905.43 65.0 12.0 7492.38 983.15 19.0 3.7 183.STAT1.ENST00000673952.1.missense.491P/A NA NA None 1.157142857142857 1.4428571428571428 False False False 0 True 0 +chr2 190982493 190982494 G C ENST00000361099.8 1 750 True True protein_coding None ENSG00000115415 missense P/A 491 STAT1 ENST00000361099.8:c.1471C>G ENSP00000354394.4:p.Pro491Ala HLA-B*45:01 9 1 9 NLSFFLTPA NLSFFLTPP MHCnuggetsI 579.17 25262.81 43.619 MHCnuggetsI 1.41 32.02 180 0.583 1475 0.52 115 0.0 172.622 79.567 5697.765 26656.16 4.678 10.226 33.51 0.004573234 0.0028321035 0.032922383 0.0657064 0.0217496692202985 0.0117352363668032 0.0038821872844515 0.0043000028722257 99.28660326086955 62.74467391304348 28049.509252607568 24332.925950445628 20.700875 10.452499999999995 25262.81 579.17 32.02 1.41 37043.32 8015.45 35.0 5.9 38565.12 25564.3 39.0 14.0 18944.44 9521.75 7.6 3.6 9.1e-05 0.000707 28.0 12.0 16763.86 3380.08 43.0 10.0 60146.45 2905.43 65.0 12.0 7492.38 983.15 19.0 3.7 171.STAT1.ENST00000361099.8.missense.491P/A NA NA None 1.157142857142857 1.4428571428571428 False False False 0 True 0 chr2 190982493 190982494 G C ENST00000392322.7 1 712 False False protein_coding None ENSG00000115415 missense P/A 491 STAT1 ENST00000392322.7:c.1471C>G ENSP00000376136.3:p.Pro491Ala HLA-B*45:01 9 1 9 NLSFFLTPA NLSFFLTPP MHCnuggetsI 579.17 25262.81 43.619 MHCnuggetsI 1.41 32.02 180 0.583 1475 0.52 115 0.0 172.622 15.069 5697.765 26656.16 4.678 10.226 33.51 0.004573234 0.0028321035 0.032922383 0.0657064 0.0217496692202985 0.0117352363668032 0.0038821872844515 0.0043000028722257 99.28660326086955 62.74467391304348 28049.509252607568 24332.925950445628 20.700875 10.452499999999995 25262.81 579.17 32.02 1.41 37043.32 8015.45 35.0 5.9 38565.12 25564.3 39.0 14.0 18944.44 9521.75 7.6 3.6 9.1e-05 0.000707 28.0 12.0 16763.86 3380.08 43.0 10.0 60146.45 2905.43 65.0 12.0 7492.38 983.15 19.0 3.7 172.STAT1.ENST00000392322.7.missense.491P/A NA NA None 1.157142857142857 1.4428571428571428 False False False 0 True 0 chr2 190982493 190982494 G C ENST00000392323.6 2 714 False False protein_coding None ENSG00000115415 missense P/A 493 STAT1 ENST00000392323.6:c.1477C>G ENSP00000376137.2:p.Pro493Ala HLA-B*45:01 9 1 9 NLSFFLTPA NLSFFLTPP MHCnuggetsI 579.17 25262.81 43.619 MHCnuggetsI 1.41 32.02 180 0.583 1475 0.52 115 0.0 172.622 5.903 5697.765 26656.16 4.678 10.226 33.51 0.004573234 0.0028321035 0.032922383 0.0657064 0.0217496692202985 0.0117352363668032 0.0038821872844515 0.0043000028722257 99.28660326086955 62.74467391304348 28049.509252607568 24332.925950445628 20.700875 10.452499999999995 25262.81 579.17 32.02 1.41 37043.32 8015.45 35.0 5.9 38565.12 25564.3 39.0 14.0 18944.44 9521.75 7.6 3.6 9.1e-05 0.000707 28.0 12.0 16763.86 3380.08 43.0 10.0 60146.45 2905.43 65.0 12.0 7492.38 983.15 19.0 3.7 173.STAT1.ENST00000392323.6.missense.493P/A NA NA None 1.157142857142857 1.4428571428571428 False False False 0 True 0 chr2 190982493 190982494 G C ENST00000673847.1 NA 779 False False protein_coding None ENSG00000115415 missense P/A 491 STAT1 ENST00000673847.1:c.1471C>G ENSP00000501185.1:p.Pro491Ala HLA-B*45:01 9 1 9 NLSFFLTPA NLSFFLTPP MHCnuggetsI 579.17 25262.81 43.619 MHCnuggetsI 1.41 32.02 180 0.583 1475 0.52 115 0.0 172.622 0.428 5697.765 26656.16 4.678 10.226 33.51 0.004573234 0.0028321035 0.032922383 0.0657064 0.0217496692202985 0.0117352363668032 0.0038821872844515 0.0043000028722257 99.28660326086955 62.74467391304348 28049.509252607568 24332.925950445628 20.700875 10.452499999999995 25262.81 579.17 32.02 1.41 37043.32 8015.45 35.0 5.9 38565.12 25564.3 39.0 14.0 18944.44 9521.75 7.6 3.6 9.1e-05 0.000707 28.0 12.0 16763.86 3380.08 43.0 10.0 60146.45 2905.43 65.0 12.0 7492.38 983.15 19.0 3.7 180.STAT1.ENST00000673847.1.missense.491P/A NA NA None 1.157142857142857 1.4428571428571428 False False False 0 True 0 @@ -789,11 +789,11 @@ chr1 223264671 223264672 G C ENST00000484758.6 2 421 False False protein_coding chr1 223264671 223264672 G C ENST00000494793.6 5 488 False False protein_coding None ENSG00000143502 missense L/V 228 SUSD4 ENST00000494793.6:c.682C>G ENSP00000476954.1:p.Leu228Val HLA-A*29:02 9 9 1 VIWSSSPPR LIWSSSPPR PickPocket 1619.56 1469.28 0.907 PickPocket 2.1 1.7 123 0.374 236 0.203 93 0.0 24.362 0.0 9344.65 8282.775 0.886 5.539 6.352 0.0015968729 0.0017330764 0.006043018 0.005986906 0.3393489681184292 0.6026078313589096 0.0273000147280735 0.0707470608833863 8.839293478260856 3.80744565217384 11685.111504428687 10912.190164727408 5.903624999999997 5.578874999999997 5308.44 5196.74 3.68 2.98 9015.15 10217.61 6.8 7.6 7131.08 8297.38 8.2 9.4 9333.45 10390.86 5.0 5.5 0.00368 0.006 5.1 4.1 1469.28 1619.56 1.7 2.1 10883.28 11634.83 20.0 20.0 7550.4 8471.69 15.0 17.0 94.SUSD4.ENST00000494793.6.missense.228L/V NA NA None -1.5714285714285714 0.5428571428571428 False False False 0 False 0 chr7 92077866 92077867 G C ENST00000356239.8 1 3907 True True protein_coding None ENSG00000127914 missense D/H 2313 AKAP9 ENST00000356239.8:c.6937G>C ENSP00000348573.3:p.Asp2313His HLA-C*06:02 9 5 5 KITTHNKVI KITTDNKVI MHCflurry 777.549 5383.442 6.924 MHCflurry 2.314 9.134 80 0.412 238 0.408 46 0.0 36.25 7.05 9351.74 21632.225 2.313 6.3 23.0 0.0063149454 0.0018926052 0.09931473 0.05441994 0.0529096869286149 0.0392111109104007 0.0211681726224742 0.1189069764262753 11.115788043478249 2.6017663043477626 5383.442338006297 777.549214261584 9.134250000000003 2.313875000000001 28393.93 24733.46 55.55 46.99 26310.17 9655.89 15.0 3.5 22090.1 9047.59 25.0 8.5 29915.46 13220.86 21.0 4.1 0.000531 0.00828 12.0 3.2 13212.86 11355.63 44.0 38.0 21174.35 3861.98 44.0 21.0 15225.45 3886.6 39.0 22.0 405.AKAP9.ENST00000356239.8.missense.2313D/H 0.97550607 0.99069834 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 chr7 92077866 92077867 G C ENST00000359028.7 5 3931 False False protein_coding None ENSG00000127914 missense D/H 2337 AKAP9 ENST00000359028.7:c.7009G>C ENSP00000351922.4:p.Asp2337His HLA-C*06:02 9 5 5 KITTHNKVI KITTDNKVI MHCflurry 777.549 5383.442 6.924 MHCflurry 2.314 9.134 80 0.412 238 0.408 46 0.0 36.25 0.74 9351.74 21632.225 2.313 6.3 23.0 0.0063149454 0.0018926052 0.09931473 0.05441994 0.0529096869286149 0.0392111109104007 0.0211681726224742 0.1189069764262753 11.115788043478249 2.6017663043477626 5383.442338006297 777.549214261584 9.134250000000003 2.313875000000001 28393.93 24733.46 55.55 46.99 26310.17 9655.89 15.0 3.5 22090.1 9047.59 25.0 8.5 29915.46 13220.86 21.0 4.1 0.000531 0.00828 12.0 3.2 13212.86 11355.63 44.0 38.0 21174.35 3861.98 44.0 21.0 15225.45 3886.6 39.0 22.0 406.AKAP9.ENST00000359028.7.missense.2337D/H 0.97550607 0.99069834 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 -chr7 92077866 92077867 G C ENST00000681412.1 NA 3923 False False protein_coding None ENSG00000127914 missense D/H 2313 AKAP9 ENST00000681412.1:c.6937G>C ENSP00000506486.1:p.Asp2313His HLA-C*06:02 9 5 5 KITTHNKVI KITTDNKVI MHCflurry 777.549 5383.442 6.924 MHCflurry 2.314 9.134 80 0.412 238 0.408 46 0.0 36.25 1.479 9351.74 21632.225 2.313 6.3 23.0 0.0063149454 0.0018926052 0.09931473 0.05441994 0.0529096869286149 0.0392111109104007 0.0211681726224742 0.1189069764262753 11.115788043478249 2.6017663043477626 5383.442338006297 777.549214261584 9.134250000000003 2.313875000000001 28393.93 24733.46 55.55 46.99 26310.17 9655.89 15.0 3.5 22090.1 9047.59 25.0 8.5 29915.46 13220.86 21.0 4.1 0.000531 0.00828 12.0 3.2 13212.86 11355.63 44.0 38.0 21174.35 3861.98 44.0 21.0 15225.45 3886.6 39.0 22.0 421.AKAP9.ENST00000681412.1.missense.2313D/H 0.97550607 0.99069834 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 +chr7 92077866 92077867 G C ENST00000394534.7 1 1571 False False protein_coding None ENSG00000127914 missense D/H 144 AKAP9 ENST00000394534.7:c.430G>C ENSP00000378042.3:p.Asp144His HLA-C*06:02 9 5 5 KITTHNKVI KITTDNKVI MHCflurry 777.549 5383.442 6.924 MHCflurry 2.314 9.134 80 0.412 238 0.408 46 0.0 36.25 0.753 9351.74 21632.225 2.313 6.3 23.0 0.0063149454 0.0018926052 0.09931473 0.05441994 0.0529096869286149 0.0392111109104007 0.0211681726224742 0.1189069764262753 11.115788043478249 2.6017663043477626 5383.442338006297 777.549214261584 9.134250000000003 2.313875000000001 28393.93 24733.46 55.55 46.99 26310.17 9655.89 15.0 3.5 22090.1 9047.59 25.0 8.5 29915.46 13220.86 21.0 4.1 0.000531 0.00828 12.0 3.2 13212.86 11355.63 44.0 38.0 21174.35 3861.98 44.0 21.0 15225.45 3886.6 39.0 22.0 407.AKAP9.ENST00000394534.7.missense.144D/H 0.97550607 0.99069834 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 chr7 92077866 92077867 G C ENST00000680513.1 NA 3860 False False protein_coding None ENSG00000127914 missense D/H 2266 AKAP9 ENST00000680513.1:c.6796G>C ENSP00000505284.1:p.Asp2266His HLA-C*06:02 9 5 5 KITTHNKVI KITTDNKVI MHCflurry 777.549 5383.442 6.924 MHCflurry 2.314 9.134 80 0.412 238 0.408 46 0.0 36.25 6.175 9351.74 21632.225 2.313 6.3 23.0 0.0063149454 0.0018926052 0.09931473 0.05441994 0.0529096869286149 0.0392111109104007 0.0211681726224742 0.1189069764262753 11.115788043478249 2.6017663043477626 5383.442338006297 777.549214261584 9.134250000000003 2.313875000000001 28393.93 24733.46 55.55 46.99 26310.17 9655.89 15.0 3.5 22090.1 9047.59 25.0 8.5 29915.46 13220.86 21.0 4.1 0.000531 0.00828 12.0 3.2 13212.86 11355.63 44.0 38.0 21174.35 3861.98 44.0 21.0 15225.45 3886.6 39.0 22.0 416.AKAP9.ENST00000680513.1.missense.2266D/H 0.97550607 0.99069834 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 chr7 92077866 92077867 G C ENST00000680534.1 NA 3920 False False protein_coding None ENSG00000127914 missense D/H 2326 AKAP9 ENST00000680534.1:c.6976G>C ENSP00000506674.1:p.Asp2326His HLA-C*06:02 9 5 5 KITTHNKVI KITTDNKVI MHCflurry 777.549 5383.442 6.924 MHCflurry 2.314 9.134 80 0.412 238 0.408 46 0.0 36.25 0.0 9351.74 21632.225 2.313 6.3 23.0 0.0063149454 0.0018926052 0.09931473 0.05441994 0.0529096869286149 0.0392111109104007 0.0211681726224742 0.1189069764262753 11.115788043478249 2.6017663043477626 5383.442338006297 777.549214261584 9.134250000000003 2.313875000000001 28393.93 24733.46 55.55 46.99 26310.17 9655.89 15.0 3.5 22090.1 9047.59 25.0 8.5 29915.46 13220.86 21.0 4.1 0.000531 0.00828 12.0 3.2 13212.86 11355.63 44.0 38.0 21174.35 3861.98 44.0 21.0 15225.45 3886.6 39.0 22.0 417.AKAP9.ENST00000680534.1.missense.2326D/H 0.97550607 0.99069834 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 chr1 119895935 119895936 C T ENST00000369400.2 NA 790 True True protein_coding None ENSG00000134249 missense R/Q 134 ADAM30 ENST00000369400.2:c.401G>A ENSP00000358407.1:p.Arg134Gln HLA-B*45:01 9 8 2 LQGVFNIDA LRGVFNIDA SMMPMBEC 531.64 2413.35 4.539 SMMPMBEC 1.9 9.0 300 0.203 0 0.0 122 0.0 0.019 0.019 9528.31 14703.57 1.543 6.2 16.0 0.0013466633 0.0059245834 0.04582563 0.16961329 0.0881104179425165 0.0205183152575045 0.0053522464469704 0.0063039702574392 46.22467391304348 37.35904891304347 25625.2994921016 16909.9485454622 13.067624999999998 4.707375 3960.35 17326.03 4.95 18.65 17803.1 6221.12 13.0 4.8 29425.27 13141.57 17.0 6.9 26647.96 12835.5 15.0 4.8 9e-05 0.000784 28.0 11.0 11604.04 1765.99 32.0 5.7 5652.1 1754.73 17.0 6.7 2413.35 531.64 9.0 1.9 49.ADAM30.ENST00000369400.2.missense.134R/Q NA NA None 0.8428571428571427 1.1285714285714286 False False False 0 False 0 -chr8 38428419 38428420 G A ENST00000683815.1 NA 818 False False protein_coding None ENSG00000077782 missense S/L 125 FGFR1 ENST00000683815.1:c.374C>T ENSP00000507997.1:p.Ser125Leu HLA-C*06:02 8 1 8 VSDALPSL VSDALPSS MHCflurry 961.402 20563.274 21.389 MHCflurry 2.345 38.442 116 1.0 1501 0.999 147 0.0 143.964 0.0 9602.945 29668.797 3.09 8.19 42.612 0.00014333251 0.0006924471 0.009799984 0.0065133898 0.0254748238949105 0.1467322995886206 0.005310650809767 0.1384094696066072 46.22467391304348 2.3454619565216603 20563.274472062043 961.4022756141565 38.44225 2.723625 6806.37 3703.91 14.66 9.58 46823.24 40079.14 88.0 43.0 38774.32 14963.56 64.0 15.0 42318.99 27006.13 66.0 17.0 2.1e-05 0.0018 39.0 6.8 8387.64 4242.33 9.0 3.5 NA NA NA NA NA NA NA NA 479.FGFR1.ENST00000683815.1.missense.125S/L NA NA None 0.3857142857142856 0.4428571428571428 False False False 0 False 0 +chr8 38428419 38428420 G A ENST00000335922.9 1 812 False False protein_coding None ENSG00000077782 missense S/L 117 FGFR1 ENST00000335922.9:c.350C>T ENSP00000337247.5:p.Ser117Leu HLA-C*06:02 8 1 8 VSDALPSL VSDALPSS MHCflurry 961.402 20563.274 21.389 MHCflurry 2.345 38.442 116 1.0 1501 0.999 147 0.0 143.964 0.679 9602.945 29668.797 3.09 8.19 42.612 0.00014333251 0.0006924471 0.009799984 0.0065133898 0.0254748238949105 0.1467322995886206 0.005310650809767 0.1384094696066072 46.22467391304348 2.3454619565216603 20563.274472062043 961.4022756141565 38.44225 2.723625 6806.37 3703.91 14.66 9.58 46823.24 40079.14 88.0 43.0 38774.32 14963.56 64.0 15.0 42318.99 27006.13 66.0 17.0 2.1e-05 0.0018 39.0 6.8 8387.64 4242.33 9.0 3.5 NA NA NA NA NA NA NA NA 460.FGFR1.ENST00000335922.9.missense.117S/L NA NA None 0.3857142857142856 0.4428571428571428 False False False 0 False 0 chr8 38428419 38428420 G A ENST00000341462.9 5 828 False False protein_coding None ENSG00000077782 missense S/L 125 FGFR1 ENST00000341462.9:c.374C>T ENSP00000340636.7:p.Ser125Leu HLA-C*06:02 8 1 8 VSDALPSL VSDALPSS MHCflurry 961.402 20563.274 21.389 MHCflurry 2.345 38.442 116 1.0 1501 0.999 147 0.0 143.964 0.0 9602.945 29668.797 3.09 8.19 42.612 0.00014333251 0.0006924471 0.009799984 0.0065133898 0.0254748238949105 0.1467322995886206 0.005310650809767 0.1384094696066072 46.22467391304348 2.3454619565216603 20563.274472062043 961.4022756141565 38.44225 2.723625 6806.37 3703.91 14.66 9.58 46823.24 40079.14 88.0 43.0 38774.32 14963.56 64.0 15.0 42318.99 27006.13 66.0 17.0 2.1e-05 0.0018 39.0 6.8 8387.64 4242.33 9.0 3.5 NA NA NA NA NA NA NA NA 461.FGFR1.ENST00000341462.9.missense.125S/L NA NA None 0.3857142857142856 0.4428571428571428 False False False 0 False 0 chr11 862686 862687 C G ENST00000409531.5 5 257 False False protein_coding None ENSG00000214063 missense I/M 86 TSPAN4 ENST00000409531.5:c.258C>G ENSP00000386899.1:p.Ile86Met HLA-A*29:02 8 3 6 AFVMAMGF AFVMAIGF NetMHCcons 1775.57 2984.62 1.681 NetMHCcons 3.1 3.9 73 1.0 550 0.996 83 0.012 72.214 1.175 9662.995 14407.605 1.491 6.15 9.35 0.0034261232 0.0041719046 0.13088052 0.18795553 0.0762897953391075 0.0206208039307966 0.0068826854484475 0.0054642480618825 37.35904891304347 46.22467391304348 18916.39649523608 19615.38223441541 10.418749999999996 10.983999999999996 5202.3 5497.02 3.01 5.7700000000000005 13503.79 8369.97 10.0 6.4 2984.62 1775.57 3.9 3.1 15311.42 10956.02 8.7 5.9 0.00263 0.00329 6.0 5.4 8478.89 6755.55 7.5 5.3 31524.63 31524.63 32.0 32.0 23875.36 20603.93 23.0 19.0 617.TSPAN4.ENST00000409531.5.missense.86I/M NA NA None 2.142857142857143 2.142857142857143 False False False 0 False 0 chr8 138737576 138737577 C A ENST00000303045.11 1 1626 True True protein_coding None ENSG00000169436 missense G/W 696 COL22A1 ENST00000303045.11:c.2086G>T ENSP00000303153.6:p.Gly696Trp HLA-B*82:02 10 1 10 GPPGLQGLRW GPPGLQGLRG PickPocket 4429.97 5997.52 1.354 MHCflurry 1.358 1.517 120 0.2 2 0.0 63 0.0 0.308 0.049 9762.161 12315.54 1.262 6.4 21.87 0.0001574231 0.00063061266 0.00035009632 0.00036294947 0.0013952069239167 0.0585502435569651 0.0090880299305624 0.0122241819004361 24.57923913043477 18.61798913043478 10791.862448618806 9762.160525037358 1.5174999999999992 1.3576249999999992 19996.69 16122.81 21.87 16.81 NA NA NA NA 12315.54 8950.22 10.0 6.4 32934.83 24720.26 32.0 14.0 0.000501 0.0154 28.0 5.0 5997.52 4429.97 6.3 5.4 NA NA NA NA NA NA NA NA 518.COL22A1.ENST00000303045.11.missense.696G/W NA NA None -0.3 0.014285714285714235 False False False 0 False 0 @@ -826,7 +826,7 @@ chr14 32773880 32773881 G T ENST00000280979.9 1 2319 True True protein_coding No chr3 122927970 122927971 G C ENST00000393583.6 2 1088 False False protein_coding None ENSG00000082684 missense I/M 223 SEMA5B ENST00000393583.6:c.669C>G ENSP00000377208.2:p.Ile223Met HLA-C*06:02 9 1 9 NLSRTIEKM NLSRTIEKI MHCnuggetsI 660.26 4589.64 6.951 MHCnuggetsI 3.22 11.08 42 1.0 0 0.0 38 0.0 0.169 0.0 11446.04 13401.455 1.171 10.4 16.04 0.0005250698 0.00033117522 0.011320976 0.006187407 0.3631537780165672 0.1833581717219203 0.1278001887295081 0.0808874584227347 2.4772826086955604 3.4218749999999147 2324.8303166377377 2041.2864109275577 5.108250000000003 4.677500000000003 4589.64 660.26 11.08 3.22 31355.09 24570.39 21.0 14.0 19295.7 16763.86 21.0 18.0 17565.08 18288.87 6.4 6.8 0.00405 0.00316 4.6 5.2 20589.91 15208.39 59.0 49.0 4506.2 3355.91 23.0 20.0 9237.83 7683.69 32.0 29.0 234.SEMA5B.ENST00000393583.6.missense.223I/M 0.98285604 0.9836632 None -1.0 -0.6714285714285715 False False False 0 True 0 chr1 52961569 52961570 C A ENST00000371513.9 1 322 False False protein_coding None ENSG00000116171 missense A/D 111 SCP2 ENST00000371513.9:c.332C>A ENSP00000360568.5:p.Ala111Asp HLA-B*82:02 9 8 2 SDHPVAPQM SAHPVAPQM PickPocket 4625.9 1501.43 0.325 NetMHCpanEL 0.93 0.21 166 0.482 219 0.534 204 0.0 51.669 0.575 11604.04 4576.12 0.394 11.63 3.359 0.009061491 0.00020715885 0.008399816 0.0017879816 0.1999325230717659 0.2564966157078743 0.082098215536862 0.0209413893795947 3.358777173912955 11.6303260869565 2132.5088166236296 11429.703923050974 0.4193749999999995 1.6227499999999992 5815.56 23898.54 7.13 28.64 NA NA NA NA 4576.12 11604.04 5.3 19.0 6009.41 18802.93 0.85 6.9 0.255 0.0949 0.21 0.93 1501.43 4625.9 4.8 13.0 NA NA NA NA NA NA NA NA 34.SCP2.ENST00000371513.9.missense.111A/D NA NA None -0.28571428571428575 -0.28571428571428575 False False False 0 False 0 chr1 36179727 36179728 G A ENST00000373150.8 2 808 False False protein_coding None ENSG00000116871 missense E/K 732 MAP7D1 ENST00000373150.8:c.2194G>A ENSP00000362243.4:p.Glu732Lys HLA-B*45:01 10 7 4 QKEKPIPQEP QKEEPIPQEP NetMHCpan 3430.92 2929.87 0.854 NetMHCpanEL 0.16 0.13 81 0.309 1643 0.326 61 0.0 93.193 28.858 11716.89 9377.202 0.8 14.065 14.466 0.009480917 0.009344879 0.010124946 0.009236105 0.0933803184889257 0.125806814758107 0.0112892128501271 0.0076564192903328 20.2322554347826 31.64317934782608 12040.433632410062 20285.65047351635 3.4677499999999988 6.27625 6713.97 9678.41 7.39 10.13 12617.94 13755.37 8.7 9.4 37333.42 37132.0 42.0 41.0 2929.87 3430.92 1.4 1.6 0.585 0.535 0.13 0.16 50000.0 50000.0 54.0 54.0 6189.99 4928.22 21.0 18.0 6294.05 4852.1 22.0 18.0 17.MAP7D1.ENST00000373150.8.missense.732E/K NA NA None -1.5999999999999999 -1.5999999999999999 True False True 0 False 0 -chr7 92077866 92077867 G C ENST00000681722.1 NA 3915 False False protein_coding None ENSG00000127914 missense D/H 2305 AKAP9 ENST00000681722.1:c.6913G>C ENSP00000506566.1:p.Asp2305His HLA-C*06:02 9 4 6 LKITTHNKV LKITTDNKV NetMHCpan 5922.97 16937.8 2.86 NetMHCpanEL 1.1 5.6 80 0.412 238 0.408 46 0.0 36.25 6.842 11726.37 15646.735 1.334 15.375 21.433 0.0009138583 0.0006798025 0.011424408 0.017053852 0.3662766674533486 0.161167926620692 0.0270961670188774 0.0211254534165249 8.839293478260856 11.115788043478249 12991.959901499167 8002.712301556041 19.636000000000006 12.310500000000005 12147.45 9210.77 23.23 18.44 14355.67 15866.8 5.4 6.1 28178.94 22818.9 35.0 26.0 16937.8 5922.97 5.9 1.5 0.00272 0.0471 5.6 1.1 9447.76 7860.43 33.0 28.0 88472.85 62778.36 67.0 61.0 19300.56 14241.97 43.0 38.0 422.AKAP9.ENST00000681722.1.missense.2305D/H 0.988977 0.9796353 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 +chr7 92077866 92077867 G C ENST00000491695.2 1 2122 False False protein_coding None ENSG00000127914 missense D/H 528 AKAP9 ENST00000491695.2:c.1582G>C ENSP00000494626.2:p.Asp528His HLA-C*06:02 9 4 6 LKITTHNKV LKITTDNKV NetMHCpan 5922.97 16937.8 2.86 NetMHCpanEL 1.1 5.6 80 0.412 238 0.408 46 0.0 36.25 1.024 11726.37 15646.735 1.334 15.375 21.433 0.0009138583 0.0006798025 0.011424408 0.017053852 0.3662766674533486 0.161167926620692 0.0270961670188774 0.0211254534165249 8.839293478260856 11.115788043478249 12991.959901499167 8002.712301556041 19.636000000000006 12.310500000000005 12147.45 9210.77 23.23 18.44 14355.67 15866.8 5.4 6.1 28178.94 22818.9 35.0 26.0 16937.8 5922.97 5.9 1.5 0.00272 0.0471 5.6 1.1 9447.76 7860.43 33.0 28.0 88472.85 62778.36 67.0 61.0 19300.56 14241.97 43.0 38.0 408.AKAP9.ENST00000491695.2.missense.528D/H 0.988977 0.9796353 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 chr7 92077866 92077867 G C ENST00000679521.1 NA 3889 False False protein_coding None ENSG00000127914 missense D/H 2295 AKAP9 ENST00000679521.1:c.6883G>C ENSP00000505456.1:p.Asp2295His HLA-C*06:02 9 4 6 LKITTHNKV LKITTDNKV NetMHCpan 5922.97 16937.8 2.86 NetMHCpanEL 1.1 5.6 80 0.412 238 0.408 46 0.0 36.25 1.672 11726.37 15646.735 1.334 15.375 21.433 0.0009138583 0.0006798025 0.011424408 0.017053852 0.3662766674533486 0.161167926620692 0.0270961670188774 0.0211254534165249 8.839293478260856 11.115788043478249 12991.959901499167 8002.712301556041 19.636000000000006 12.310500000000005 12147.45 9210.77 23.23 18.44 14355.67 15866.8 5.4 6.1 28178.94 22818.9 35.0 26.0 16937.8 5922.97 5.9 1.5 0.00272 0.0471 5.6 1.1 9447.76 7860.43 33.0 28.0 88472.85 62778.36 67.0 61.0 19300.56 14241.97 43.0 38.0 411.AKAP9.ENST00000679521.1.missense.2295D/H 0.988977 0.9796353 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 chr7 92077866 92077867 G C ENST00000679821.1 NA 3821 False False protein_coding None ENSG00000127914 missense D/H 2227 AKAP9 ENST00000679821.1:c.6679G>C ENSP00000506040.1:p.Asp2227His HLA-C*06:02 9 4 6 LKITTHNKV LKITTDNKV NetMHCpan 5922.97 16937.8 2.86 NetMHCpanEL 1.1 5.6 80 0.412 238 0.408 46 0.0 36.25 0.777 11726.37 15646.735 1.334 15.375 21.433 0.0009138583 0.0006798025 0.011424408 0.017053852 0.3662766674533486 0.161167926620692 0.0270961670188774 0.0211254534165249 8.839293478260856 11.115788043478249 12991.959901499167 8002.712301556041 19.636000000000006 12.310500000000005 12147.45 9210.77 23.23 18.44 14355.67 15866.8 5.4 6.1 28178.94 22818.9 35.0 26.0 16937.8 5922.97 5.9 1.5 0.00272 0.0471 5.6 1.1 9447.76 7860.43 33.0 28.0 88472.85 62778.36 67.0 61.0 19300.56 14241.97 43.0 38.0 412.AKAP9.ENST00000679821.1.missense.2227D/H 0.988977 0.9796353 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 chr7 92077866 92077867 G C ENST00000680072.1 NA 3848 False False protein_coding None ENSG00000127914 missense D/H 2254 AKAP9 ENST00000680072.1:c.6760G>C ENSP00000506581.1:p.Asp2254His HLA-C*06:02 9 4 6 LKITTHNKV LKITTDNKV NetMHCpan 5922.97 16937.8 2.86 NetMHCpanEL 1.1 5.6 80 0.412 238 0.408 46 0.0 36.25 0.089 11726.37 15646.735 1.334 15.375 21.433 0.0009138583 0.0006798025 0.011424408 0.017053852 0.3662766674533486 0.161167926620692 0.0270961670188774 0.0211254534165249 8.839293478260856 11.115788043478249 12991.959901499167 8002.712301556041 19.636000000000006 12.310500000000005 12147.45 9210.77 23.23 18.44 14355.67 15866.8 5.4 6.1 28178.94 22818.9 35.0 26.0 16937.8 5922.97 5.9 1.5 0.00272 0.0471 5.6 1.1 9447.76 7860.43 33.0 28.0 88472.85 62778.36 67.0 61.0 19300.56 14241.97 43.0 38.0 413.AKAP9.ENST00000680072.1.missense.2254D/H 0.988977 0.9796353 None -0.4714285714285714 -0.4714285714285714 False False False 0 False 0 diff --git a/tests/test_data/top_score_filter/output_lowest.tsv b/tests/test_data/top_score_filter/output_lowest.tsv index 6d8ad9067..f071c1fec 100644 --- a/tests/test_data/top_score_filter/output_lowest.tsv +++ b/tests/test_data/top_score_filter/output_lowest.tsv @@ -1,24 +1,24 @@ -Chromosome Start Stop Reference Variant Transcript Transcript Support Level Transcript Length Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Mutation Protein Position Gene Name HGVSc HGVSp HLA Allele Peptide Length Sub-peptide Position Mutation Position MT Epitope Seq WT Epitope Seq Best MT IC50 Score Method Best MT IC50 Score Corresponding WT IC50 Score Corresponding Fold Change Best MT Percentile Method Best MT Percentile Corresponding WT Percentile Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Median MT IC50 Score Median WT IC50 Score Median Fold Change Median MT Percentile Median WT Percentile NetMHC WT Score NetMHC MT Score NetMHC WT Percentile NetMHC MT Percentile PickPocket WT Score PickPocket MT Score PickPocket WT Percentile PickPocket MT Percentile Index cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count NNalign WT Score NNalign MT Score NNalign WT Percentile NNalign MT Percentile -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 9 7 GWEFLAFTRLTSELN GWEFLASTRLTSELN NNalign 16.2 15.4 0.951 NNalign 1.6 1.4 171 0.959 NA NA NA NA NA NA 16.2 15.4 0.951 1.6 1.4 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F -0.7714285714285715 1.4000000000000001 False False False 0 False 0 15.4 16.2 1.4 1.6 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 9 7 TTVVVTTQKRNSRRQ TTVVVTAQKRNSRRQ NNalign 18.2 15.0 0.824 NNalign 1.8 1.4 96 0.042 NA NA NA NA NA NA 18.2 15.0 0.824 1.8 1.4 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6000000000000005 1.4000000000000001 False False False 0 False 0 15.0 18.2 1.4 1.8 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 8 8 SLFGALVRSRTYDMD SLFGALVHSRTYDMD NNalign 31.0 168.6 5.439 NNalign 3.2 14.0 210 0.686 NA NA NA NA NA NA 31.0 168.6 5.439 3.2 14.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.7714285714285716 2.1714285714285713 False False False 0 False 0 168.6 31.0 14.0 3.2 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 6 10 LYYSYGLLHIYGSGG LYYSYGLLHTYGSGG NNalign 223.0 300.9 1.349 NNalign 16.0 19.0 120 0.233 NA NA NA NA NA NA 223.0 300.9 1.349 16.0 19.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.2857142857142857 0.9714285714285714 False False False 0 False 0 300.9 223.0 19.0 16.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 13 3 GKHGGVSLSKIERST GKPGGVSLSKIERST NNalign 282.5 349.6 1.238 NNalign 18.0 20.0 140 0.179 NA NA NA NA NA NA 282.5 349.6 1.238 18.0 20.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -1.3857142857142857 0.9428571428571428 False False False 0 False 0 349.6 282.5 20.0 18.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 10 1, 2, 3, 4, 5 LSRTLLLAAAGGSSL TLSRTLLAAAGGSSL NNalign 428.3 681.6 1.591 NNalign 23.0 29.0 76 0.158 NA NA NA NA NA NA 428.3 681.6 1.591 23.0 29.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 0.7142857142857143 2.342857142857143 False False False 0 False 0 681.6 428.3 29.0 23.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 2 14 TALAIAGTLKFNPQT TALAIAGTLKFNPET NNalign 429.6 547.5 1.274 NNalign 23.0 26.0 136 0.25 NA NA NA NA NA NA 429.6 547.5 1.274 23.0 26.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 2.085714285714286 False False False 0 False 1 547.5 429.6 26.0 23.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 13 3 ELVYCLQKCNVPLFV ELAYCLQKCNVPLFV NNalign 488.8 855.7 1.751 NNalign 25.0 32.0 113 0.053 NA NA NA NA NA NA 488.8 855.7 1.751 25.0 32.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 1.7714285714285711 1.7714285714285711 True False False 2 False 0 855.7 488.8 32.0 25.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 13 3 MDYLSDRCKILQVFD MDCLSDRCKILQVFD NNalign 586.5 2679.7 4.569 NNalign 27.0 53.0 92 0.043 NA NA NA NA NA NA 586.5 2679.7 4.569 27.0 53.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y 0.6285714285714287 1.4857142857142858 False False False 1 False 0 2679.7 586.5 53.0 27.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 3 13 HVASVLCQRAKVEMS HVASVLCQRAKVAMS NNalign 770.7 370.4 0.481 NNalign 31.0 21.0 113 0.044 NA NA NA NA NA NA 770.7 370.4 0.481 31.0 21.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -0.6857142857142857 1.7857142857142858 False False False 1 False 0 370.4 770.7 21.0 31.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 4 12 YVQWYQQRPGSAPTT YVQWYQQRPGSSPTT NNalign 1129.7 1129.4 1.0 NNalign 37.0 37.0 7 0.571 NA NA NA NA NA NA 1129.7 1129.4 1.0 37.0 37.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5714285714285714 -0.5714285714285714 False False False 0 False 0 1129.4 1129.7 37.0 37.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 13 1, 2, 4, 5 LPLLPLLLLLGASGG PLLPLLLLLLGASGG NNalign 1135.5 2570.9 2.264 NNalign 37.0 53.0 101 0.891 NA NA NA NA NA NA 1135.5 2570.9 2.264 37.0 53.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.057142857142857 3.028571428571429 False False False 0 False 0 2570.9 1135.5 53.0 37.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 9 1 ARPPQQPVP PRPPQQPVP PickPocket 1654.99 4242.33 2.563 PickPocket 0.4 4.8 245 0.486 NA NA NA NA NA NA 6693.895 10556.225 1.577 0.485 3.2 16870.12 11732.8 1.6 0.57 4242.33 1654.99 4.8 0.4 15.GGA1.ENST00000343632.4.missense.484P/A -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 NA NA NA NA -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 1 15 ASLASLMVCELAGNL ASLASLMVCELAGNP NNalign 1739.7 1772.2 1.019 NNalign 45.0 45.0 303 0.135 NA NA NA NA NA NA 1739.7 1772.2 1.019 45.0 45.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6428571428571427 2.457142857142857 False False False 1 False 0 1772.2 1739.7 45.0 45.0 -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 7 3 WTHSRDPEG WTRSRDPEG PickPocket 2523.8 1765.99 0.7 PickPocket 1.4 0.5 56 0.071 NA NA NA NA NA NA 19369.23 18322.905 0.946 12.7 10.25 34879.82 36214.66 20.0 24.0 1765.99 2523.8 0.5 1.4 5.CECR2.ENST00000262608.8.missense.535R/H -2.5 -2.1714285714285717 False False False 0 False 0 NA NA NA NA -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 5 11 PGKTVTISCTGSSGS PGKTVTISCTRSSGS NNalign 2994.6 726.8 0.243 NNalign 56.0 30.0 5 1.0 NA NA NA NA NA NA 2994.6 726.8 0.243 56.0 30.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.20000000000000004 1.2285714285714284 False False False 1 False 0 726.8 2994.6 30.0 56.0 -22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-E*01:01 9 9 9 NMSSFKLKQ NMSSFKLKE PickPocket 3890.57 3848.7 0.989 PickPocket 4.0 3.9 117 0.496 NA NA NA NA NA NA 17113.26 17432.18 1.019 8.0 8.45 31015.66 30335.95 13.0 12.0 3848.7 3890.57 3.9 4.0 14.LGALS2.ENST00000215886.4.missense.132E/Q -0.9000000000000001 -0.07142857142857155 False False False 0 True 0 NA NA NA NA -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 14 2 KTQEVKVKEPPKKAE KPQEVKVKEPPKKAE NNalign 4730.4 4999.5 1.057 NNalign 66.0 68.0 185 0.038 NA NA NA NA NA NA 4730.4 4999.5 1.057 66.0 68.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.314285714285714 -0.8714285714285713 False False False 0 False 0 4999.5 4730.4 68.0 66.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 2 8 SVNEALNNL SVNEALNHL PickPocket 4989.87 7775.84 1.558 PickPocket 7.3 15.0 30 0.1 NA NA NA NA NA NA 4989.87 7775.84 1.558 7.3 15.0 NA NA NA NA 7775.84 4989.87 15.0 7.3 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 8 2 GYESRVEPP GSESRVEPP PickPocket 5620.54 22209.93 3.952 PickPocket 8.7 44.0 116 0.043 NA NA NA NA NA NA 5620.54 22209.93 3.952 8.7 44.0 NA NA NA NA 22209.93 5620.54 44.0 8.7 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.6142857142857143 -1.4000000000000001 False False True 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 7 3 ANQDAAQGI ANEDAAQGI PickPocket 5681.68 9654.43 1.699 PickPocket 8.8 20.0 22 0.5 NA NA NA NA NA NA 5681.68 9654.43 1.699 8.8 20.0 NA NA NA NA 9654.43 5681.68 20.0 8.8 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 -0.4000000000000001 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 16 NA GEKAGCPWS NA PickPocket 8119.76 NA NA PickPocket 18.0 NA 142 0.768 NA NA NA NA NA NA 23066.335 NA NA 24.5 NA NA 38012.91 NA 31.0 NA 8119.76 NA 18.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 NA NA NA NA -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-DRB1*11:01 15 8 1 SAAAAAAAVIPTVST AAAAAAAAVIPTVST NNalign 14537.0 14673.4 1.009 NNalign 89.0 89.0 128 0.977 NA NA NA NA NA NA 14537.0 14673.4 1.009 89.0 89.0 NA NA NA NA NA NA NA NA 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 1.3 2.5285714285714285 False False False 0 False 0 14673.4 14537.0 89.0 89.0 +Chromosome Start Stop Reference Variant Transcript Transcript Support Level Transcript Length Canonical MANE Select Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Mutation Protein Position Gene Name HGVSc HGVSp HLA Allele Peptide Length Sub-peptide Position Mutation Position MT Epitope Seq WT Epitope Seq Best MT IC50 Score Method Best MT IC50 Score Corresponding WT IC50 Score Corresponding Fold Change Best MT Percentile Method Best MT Percentile Corresponding WT Percentile Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Median MT IC50 Score Median WT IC50 Score Median Fold Change Median MT Percentile Median WT Percentile NetMHC WT IC50 Score NetMHC MT IC50 Score NetMHC WT Percentile NetMHC MT Percentile PickPocket WT IC50 Score PickPocket MT IC50 Score PickPocket WT Percentile PickPocket MT Percentile Index Gene of Interest cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 5 5 KFNPQTDYL KFNPETDYL PickPocket 1262.76 1318.61 1.044 PickPocket 0.5 0.6 136 0.25 NA NA NA NA NA NA 1262.76 1318.61 1.044 0.5 0.6 NA NA NA NA 1318.61 1262.76 0.6 0.5 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.4714285714285715 -1.4714285714285715 False False False 0 False 1 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-E*01:01 9 4 6 QRPGSAPTT QRPGSSPTT PickPocket 1362.11 1517.76 1.114 PickPocket 0.3 0.3 7 0.571 NA NA NA NA NA NA 6537.82 9406.765 1.439 0.435 1.05 17295.77 11713.53 1.8 0.57 1517.76 1362.11 0.3 0.3 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -0.5714285714285714 -0.5714285714285714 True False False 0 False 0 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 1 10 LYYSYGLLHI LYYSYGLLHT PickPocket 1469.28 2365.16 1.61 PickPocket 0.3 0.4 120 0.233 NA NA NA NA NA NA 1469.28 2365.16 1.61 0.3 0.4 NA NA NA NA 2365.16 1469.28 0.4 0.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9142857142857143 0.9142857142857143 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 9 1 ARPPQQPVP PRPPQQPVP PickPocket 1654.99 4242.33 2.563 PickPocket 0.4 4.8 245 0.486 NA NA NA NA NA NA 6693.895 10556.225 1.577 0.485 3.2 16870.12 11732.8 1.6 0.57 4242.33 1654.99 4.8 0.4 15.GGA1.ENST00000343632.4.missense.484P/A False -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-E*01:01 9 1 9 YQPCDDMDY YQPCDDMDC PickPocket 1864.16 1804.62 0.968 PickPocket 0.6 0.6 92 0.043 NA NA NA NA NA NA 15927.085 16858.635 1.058 5.2 7.3 31912.65 29990.01 14.0 9.8 1804.62 1864.16 0.6 0.6 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 2 9 ATLSRTLLL ATLSRTLLA PickPocket 2122.61 3272.12 1.542 NetMHC 0.12 5.1 76 0.158 NA NA NA NA NA NA 3816.925 14131.865 3.702 0.51 3.8 24991.61 5511.24 5.1 0.12 3272.12 2122.61 2.5 0.9 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.3142857142857143 1.3142857142857143 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-E*01:01 9 7 3 WTHSRDPEG WTRSRDPEG PickPocket 2523.8 1765.99 0.7 PickPocket 1.4 0.5 56 0.071 NA NA NA NA NA NA 19369.23 18322.905 0.946 12.7 10.25 34879.82 36214.66 20.0 24.0 1765.99 2523.8 0.5 1.4 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5 -2.1714285714285717 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 6 6 LLPLLPLLL LLPLLLLLL PickPocket 2551.25 3099.81 1.215 NetMHC 0.17 0.33 101 0.891 NA NA NA NA NA NA 4721.43 6167.26 1.306 0.785 1.265 9234.71 6891.61 0.33 0.17 3099.81 2551.25 2.2 1.4 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 8 2 LVYCLQKCN LAYCLQKCN PickPocket 3099.81 6399.79 2.065 PickPocket 3.3 12.0 113 0.053 NA NA NA NA NA NA 3099.81 6399.79 2.065 3.3 12.0 NA NA NA NA 6399.79 3099.81 12.0 3.3 6.USP18.ENST00000215794.7.missense.124A/V False -0.4857142857142857 0.7999999999999999 False False False 2 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-E*01:01 9 6 4 FLAFTRLTS FLASTRLTS PickPocket 3343.7 3202.08 0.958 PickPocket 2.7 2.4 171 0.959 NA NA NA NA NA NA 20419.935 19400.67 0.95 15.85 12.2 35599.26 37496.17 22.0 29.0 3202.08 3343.7 2.4 2.7 22.PANX2.ENST00000395842.2.missense.147S/F False 0.24285714285714272 1.4000000000000001 False False False 0 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 1 9 MVCELAGNL MVCELAGNP PickPocket 3454.02 10191.11 2.951 PickPocket 4.1 21.0 303 0.135 NA NA NA NA NA NA 3454.02 10191.11 2.951 4.1 21.0 NA NA NA NA 10191.11 3454.02 21.0 4.1 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6428571428571427 1.4714285714285713 False False False 1 False 0 +22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 Not Run Not Run protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-E*01:01 9 9 9 NMSSFKLKQ NMSSFKLKE PickPocket 3890.57 3848.7 0.989 PickPocket 4.0 3.9 117 0.496 NA NA NA NA NA NA 17113.26 17432.18 1.019 8.0 8.45 31015.66 30335.95 13.0 12.0 3848.7 3890.57 3.9 4.0 14.LGALS2.ENST00000215886.4.missense.132E/Q False -0.9000000000000001 -0.07142857142857155 False False False 0 True 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-E*01:01 9 9 1 EMSHFEPNE AMSHFEPNE PickPocket 3932.89 2443.19 0.621 PickPocket 4.2 1.3 113 0.044 NA NA NA NA NA NA 17166.29 15315.03 0.892 8.1 4.5 28186.87 30399.69 7.7 12.0 2443.19 3932.89 1.3 4.2 18.ACO2.ENST00000216254.4.missense.33A/E False -1.9000000000000001 -1.1285714285714286 True False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 9 1 RSRTYDMDV HSRTYDMDV PickPocket 4576.12 7609.38 1.663 PickPocket 6.3 15.0 210 0.686 NA NA NA NA NA NA 4576.12 7609.38 1.663 6.3 15.0 NA NA NA NA 7609.38 4576.12 15.0 6.3 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 2 8 SVNEALNNL SVNEALNHL PickPocket 4989.87 7775.84 1.558 PickPocket 7.3 15.0 30 0.1 NA NA NA NA NA NA 4989.87 7775.84 1.558 7.3 15.0 NA NA NA NA 7775.84 4989.87 15.0 7.3 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 8 2 GYESRVEPP GSESRVEPP PickPocket 5620.54 22209.93 3.952 PickPocket 8.7 44.0 116 0.043 NA NA NA NA NA NA 5620.54 22209.93 3.952 8.7 44.0 NA NA NA NA 22209.93 5620.54 44.0 8.7 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.6142857142857143 -1.4000000000000001 False False True 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 7 3 ANQDAAQGI ANEDAAQGI PickPocket 5681.68 9654.43 1.699 PickPocket 8.8 20.0 22 0.5 NA NA NA NA NA NA 5681.68 9654.43 1.699 8.8 20.0 NA NA NA NA 9654.43 5681.68 20.0 8.8 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 -0.4000000000000001 False False False 0 False 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 8 2 KHGGVSLSK KPGGVSLSK PickPocket 6539.79 20149.14 3.081 PickPocket 13.0 53.0 140 0.179 NA NA NA NA NA NA 24389.595 31577.025 1.295 34.5 57.5 43004.91 42239.4 62.0 56.0 20149.14 6539.79 53.0 13.0 11.TPST2.ENST00000338754.4.missense.274P/H False 0.24285714285714294 0.3428571428571429 False False False 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 8 2 KTQEVKVKE KPQEVKVKE PickPocket 7366.35 25842.4 3.508 PickPocket 14.0 50.0 185 0.038 NA NA NA NA NA NA 7366.35 25842.4 3.508 14.0 50.0 NA NA NA NA 25842.4 7366.35 50.0 14.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.4142857142857141 -1.014285714285714 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-E*01:01 9 16 NA GEKAGCPWS NA PickPocket 8119.76 NA NA PickPocket 18.0 NA 142 0.768 NA NA NA NA NA NA 23066.335 NA NA 24.5 NA NA 38012.91 NA 31.0 NA 8119.76 NA 18.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.4714285714285714 -0.4714285714285714 False False False 1 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 1 9 KTVTISCTG KTVTISCTR PickPocket 9447.76 15208.39 1.61 PickPocket 19.0 31.0 5 1.0 NA NA NA NA NA NA 9447.76 15208.39 1.61 19.0 31.0 NA NA NA NA 15208.39 9447.76 31.0 19.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 1.2285714285714284 1.2285714285714284 False False False 1 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 2 8 KTTVVVTTQ KTTVVVTAQ PickPocket 10874.65 16763.86 1.542 PickPocket 23.0 34.0 96 0.042 NA NA NA NA NA NA 10874.65 16763.86 1.542 23.0 34.0 NA NA NA NA 16763.86 10874.65 34.0 23.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.0000000000000002 1.4000000000000001 False False False 0 False 0 +4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 Not Run Not Run protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-E*01:01 9 2 9 SAAAAAAAV SAAAAAAAA PickPocket 21040.32 21040.32 1.0 NetMHC 21.0 30.0 128 0.977 NA NA NA NA NA NA 28125.2 29506.67 1.049 38.0 42.5 37973.02 35210.08 30.0 21.0 21040.32 21040.32 55.0 55.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A False 2.142857142857143 2.142857142857143 False False False 0 False 0 diff --git a/tests/test_data/top_score_filter/output_median.tsv b/tests/test_data/top_score_filter/output_median.tsv index 836db4e76..a9ccd0d3f 100644 --- a/tests/test_data/top_score_filter/output_median.tsv +++ b/tests/test_data/top_score_filter/output_median.tsv @@ -1,24 +1,24 @@ -Chromosome Start Stop Reference Variant Transcript Transcript Support Level Transcript Length Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Mutation Protein Position Gene Name HGVSc HGVSp HLA Allele Peptide Length Sub-peptide Position Mutation Position MT Epitope Seq WT Epitope Seq Best MT IC50 Score Method Best MT IC50 Score Corresponding WT IC50 Score Corresponding Fold Change Best MT Percentile Method Best MT Percentile Corresponding WT Percentile Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Median MT IC50 Score Median WT IC50 Score Median Fold Change Median MT Percentile Median WT Percentile NetMHC WT Score NetMHC MT Score NetMHC WT Percentile NetMHC MT Percentile PickPocket WT Score PickPocket MT Score PickPocket WT Percentile PickPocket MT Percentile Index cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count NNalign WT Score NNalign MT Score NNalign WT Percentile NNalign MT Percentile -22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-DRB1*11:01 15 9 7 GWEFLAFTRLTSELN GWEFLASTRLTSELN NNalign 16.2 15.4 0.951 NNalign 1.6 1.4 171 0.959 NA NA NA NA NA NA 16.2 15.4 0.951 1.6 1.4 NA NA NA NA NA NA NA NA 22.PANX2.ENST00000395842.2.missense.147S/F -0.7714285714285715 1.4000000000000001 False False False 0 False 0 15.4 16.2 1.4 1.6 -22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-DRB1*11:01 15 9 7 TTVVVTTQKRNSRRQ TTVVVTAQKRNSRRQ NNalign 18.2 15.0 0.824 NNalign 1.8 1.4 96 0.042 NA NA NA NA NA NA 18.2 15.0 0.824 1.8 1.4 NA NA NA NA NA NA NA NA 21.MOV10L1.ENST00000262794.5.missense.482A/T -3.6000000000000005 1.4000000000000001 False False False 0 False 0 15.0 18.2 1.4 1.8 -22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-DRB1*11:01 15 8 8 SLFGALVRSRTYDMD SLFGALVHSRTYDMD NNalign 31.0 168.6 5.439 NNalign 3.2 14.0 210 0.686 NA NA NA NA NA NA 31.0 168.6 5.439 3.2 14.0 NA NA NA NA NA NA NA NA 23.TUBGCP6.ENST00000248846.5.missense.220H/R -1.7714285714285716 2.1714285714285713 False False False 0 False 0 168.6 31.0 14.0 3.2 -22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-DRB1*11:01 15 6 10 LYYSYGLLHIYGSGG LYYSYGLLHTYGSGG NNalign 223.0 300.9 1.349 NNalign 16.0 19.0 120 0.233 NA NA NA NA NA NA 223.0 300.9 1.349 16.0 19.0 NA NA NA NA NA NA NA NA 20.PKDREJ.ENST00000253255.5.missense.1875T/I -0.2857142857142857 0.9714285714285714 False False False 0 False 0 300.9 223.0 19.0 16.0 -22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-DRB1*11:01 15 13 3 GKHGGVSLSKIERST GKPGGVSLSKIERST NNalign 282.5 349.6 1.238 NNalign 18.0 20.0 140 0.179 NA NA NA NA NA NA 282.5 349.6 1.238 18.0 20.0 NA NA NA NA NA NA NA NA 11.TPST2.ENST00000338754.4.missense.274P/H -1.3857142857142857 0.9428571428571428 False False False 0 False 0 349.6 282.5 20.0 18.0 -6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-DRB1*11:01 15 10 1, 2, 3, 4, 5 LSRTLLLAAAGGSSL TLSRTLLAAAGGSSL NNalign 428.3 681.6 1.591 NNalign 23.0 29.0 76 0.158 NA NA NA NA NA NA 428.3 681.6 1.591 23.0 29.0 NA NA NA NA NA NA NA NA 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L 0.7142857142857143 2.342857142857143 False False False 0 False 0 681.6 428.3 29.0 23.0 -22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-DRB1*11:01 15 2 14 TALAIAGTLKFNPQT TALAIAGTLKFNPET NNalign 429.6 547.5 1.274 NNalign 23.0 26.0 136 0.25 NA NA NA NA NA NA 429.6 547.5 1.274 23.0 26.0 NA NA NA NA NA NA NA NA 19.ACO2.ENST00000216254.4.missense.510E/Q -0.942857142857143 2.085714285714286 False False False 0 False 1 547.5 429.6 26.0 23.0 -22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-DRB1*11:01 15 13 3 ELVYCLQKCNVPLFV ELAYCLQKCNVPLFV NNalign 488.8 855.7 1.751 NNalign 25.0 32.0 113 0.053 NA NA NA NA NA NA 488.8 855.7 1.751 25.0 32.0 NA NA NA NA NA NA NA NA 6.USP18.ENST00000215794.7.missense.124A/V 1.7714285714285711 1.7714285714285711 True False False 2 False 0 855.7 488.8 32.0 25.0 -22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-DRB1*11:01 15 13 3 MDYLSDRCKILQVFD MDCLSDRCKILQVFD NNalign 586.5 2679.7 4.569 NNalign 27.0 53.0 92 0.043 NA NA NA NA NA NA 586.5 2679.7 4.569 27.0 53.0 NA NA NA NA NA NA NA NA 17.CACNA1I.ENST00000402142.3.missense.107C/Y 0.6285714285714287 1.4857142857142858 False False False 1 False 0 2679.7 586.5 53.0 27.0 -22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-DRB1*11:01 15 3 13 HVASVLCQRAKVEMS HVASVLCQRAKVAMS NNalign 770.7 370.4 0.481 NNalign 31.0 21.0 113 0.044 NA NA NA NA NA NA 770.7 370.4 0.481 31.0 21.0 NA NA NA NA NA NA NA NA 18.ACO2.ENST00000216254.4.missense.33A/E -0.6857142857142857 1.7857142857142858 False False False 1 False 0 370.4 770.7 21.0 31.0 -22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-DRB1*11:01 15 4 12 YVQWYQQRPGSAPTT YVQWYQQRPGSSPTT NNalign 1129.7 1129.4 1.0 NNalign 37.0 37.0 7 0.571 NA NA NA NA NA NA 1129.7 1129.4 1.0 37.0 37.0 NA NA NA NA NA NA NA NA 10.IGLV6-57.ENST00000390285.3.missense.63S/A -0.5714285714285714 -0.5714285714285714 False False False 0 False 0 1129.4 1129.7 37.0 37.0 -2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-DRB1*11:01 15 13 1, 2, 4, 5 LPLLPLLLLLGASGG PLLPLLLLLLGASGG NNalign 1135.5 2570.9 2.264 NNalign 37.0 53.0 101 0.891 NA NA NA NA NA NA 1135.5 2570.9 2.264 37.0 53.0 NA NA NA NA NA NA NA NA 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP 1.057142857142857 3.028571428571429 False False False 0 False 0 2570.9 1135.5 53.0 37.0 -22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-DRB1*11:01 15 1 15 ASLASLMVCELAGNL ASLASLMVCELAGNP NNalign 1739.7 1772.2 1.019 NNalign 45.0 45.0 303 0.135 NA NA NA NA NA NA 1739.7 1772.2 1.019 45.0 45.0 NA NA NA NA NA NA NA NA 13.ELFN2.ENST00000402918.2.missense.186P/L 0.6428571428571427 2.457142857142857 False False False 1 False 0 1772.2 1739.7 45.0 45.0 -22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-DRB1*11:01 15 5 11 PGKTVTISCTGSSGS PGKTVTISCTRSSGS NNalign 2994.6 726.8 0.243 NNalign 56.0 30.0 5 1.0 NA NA NA NA NA NA 2994.6 726.8 0.243 56.0 30.0 NA NA NA NA NA NA NA NA 9.IGLV6-57.ENST00000390285.3.missense.43R/G -0.20000000000000004 1.2285714285714284 False False False 1 False 0 726.8 2994.6 30.0 56.0 -22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-DRB1*11:01 15 4 12 TSLLHTVSPEPARPP TSLLHTVSPEPPRPP NNalign 3433.3 6964.2 2.028 NNalign 59.0 75.0 245 0.486 NA NA NA NA NA NA 3433.3 6964.2 2.028 59.0 75.0 NA NA NA NA NA NA NA NA 15.GGA1.ENST00000343632.4.missense.484P/A -1.7999999999999996 0.9142857142857143 False False True 0 False 0 6964.2 3433.3 75.0 59.0 -22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-DRB1*11:01 15 14 2 KTQEVKVKEPPKKAE KPQEVKVKEPPKKAE NNalign 4730.4 4999.5 1.057 NNalign 66.0 68.0 185 0.038 NA NA NA NA NA NA 4730.4 4999.5 1.057 66.0 68.0 NA NA NA NA NA NA NA NA 12.NEFH.ENST00000310624.6.missense.830P/T -2.314285714285714 -0.8714285714285713 False False False 0 False 0 4999.5 4730.4 68.0 66.0 -22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 2 8 SVNEALNNL SVNEALNHL PickPocket 4989.87 7775.84 1.558 PickPocket 7.3 15.0 30 0.1 NA NA NA NA NA NA 4989.87 7775.84 1.558 7.3 15.0 NA NA NA NA 7775.84 4989.87 15.0 7.3 7.CLTCL1.ENST00000263200.10.missense.1469H/N -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 NA NA NA NA -22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 7 3 WTHSRDPEG WTRSRDPEG PickPocket 5500.22 19932.31 3.624 PickPocket 8.4 40.0 56 0.071 NA NA NA NA NA NA 5500.22 19932.31 3.624 8.4 40.0 NA NA NA NA 19932.31 5500.22 40.0 8.4 5.CECR2.ENST00000262608.8.missense.535R/H -2.5 -2.1714285714285717 False False False 0 False 0 NA NA NA NA -22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 8 2 GYESRVEPP GSESRVEPP PickPocket 5620.54 22209.93 3.952 PickPocket 8.7 44.0 116 0.043 NA NA NA NA NA NA 5620.54 22209.93 3.952 8.7 44.0 NA NA NA NA 22209.93 5620.54 44.0 8.7 24.PPP6R2.ENST00000395741.3.missense.414S/Y -1.6142857142857143 -1.4000000000000001 False False True 0 False 0 NA NA NA NA -22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 7 3 ANQDAAQGI ANEDAAQGI PickPocket 5681.68 9654.43 1.699 PickPocket 8.8 20.0 22 0.5 NA NA NA NA NA NA 5681.68 9654.43 1.699 8.8 20.0 NA NA NA NA 9654.43 5681.68 20.0 8.8 8.FAM230A.ENST00000434783.3.missense.322E/Q -0.4000000000000001 -0.4000000000000001 False False False 0 False 0 NA NA NA NA -22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-DRB1*11:01 15 21 NA SGEKAGCPWSGTGQH NA NNalign 11805.0 NA NA NNalign 86.0 NA 142 0.768 NA NA NA NA NA NA 11805.0 NA NA 86.0 NA NA NA NA NA NA NA NA NA 16.TRIOBP.ENST00000406386.3.FS.219GA/G -1.4142857142857141 0.02857142857142855 False False False 1 False 0 NA 11805.0 NA 86.0 -4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-DRB1*11:01 15 8 1 SAAAAAAAVIPTVST AAAAAAAAVIPTVST NNalign 14537.0 14673.4 1.009 NNalign 89.0 89.0 128 0.977 NA NA NA NA NA NA 14537.0 14673.4 1.009 89.0 89.0 NA NA NA NA NA NA NA NA 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A 1.3 2.5285714285714285 False False False 0 False 0 14673.4 14537.0 89.0 89.0 -22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-E*01:01 9 9 9 NMSSFKLKQ NMSSFKLKE PickPocket 3890.57 3848.7 0.989 PickPocket 4.0 3.9 117 0.496 NA NA NA NA NA NA 17113.26 17432.18 1.019 8.0 8.45 31015.66 30335.95 13.0 12.0 3848.7 3890.57 3.9 4.0 14.LGALS2.ENST00000215886.4.missense.132E/Q -0.9000000000000001 -0.07142857142857155 False False False 0 True 0 NA NA NA NA +Chromosome Start Stop Reference Variant Transcript Transcript Support Level Transcript Length Canonical MANE Select Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Mutation Protein Position Gene Name HGVSc HGVSp HLA Allele Peptide Length Sub-peptide Position Mutation Position MT Epitope Seq WT Epitope Seq Best MT IC50 Score Method Best MT IC50 Score Corresponding WT IC50 Score Corresponding Fold Change Best MT Percentile Method Best MT Percentile Corresponding WT Percentile Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Median MT IC50 Score Median WT IC50 Score Median Fold Change Median MT Percentile Median WT Percentile NetMHC WT IC50 Score NetMHC MT IC50 Score NetMHC WT Percentile NetMHC MT Percentile PickPocket WT IC50 Score PickPocket MT IC50 Score PickPocket WT Percentile PickPocket MT Percentile Index Gene of Interest cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count +22 41920894 41920895 G C ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense E/Q 510 ACO2 ENST00000216254.4:c.1528G>C ENSP00000216254.4:p.Glu510Gln HLA-G*01:09 9 5 5 KFNPQTDYL KFNPETDYL PickPocket 1262.76 1318.61 1.044 PickPocket 0.5 0.6 136 0.25 NA NA NA NA NA NA 1262.76 1318.61 1.044 0.5 0.6 NA NA NA NA 1318.61 1262.76 0.6 0.5 19.ACO2.ENST00000216254.4.missense.510E/Q False -1.4714285714285715 -1.4714285714285715 False False False 0 False 1 +22 46653595 46653596 G A ENST00000253255.5 Not Supported 2253 Not Run Not Run protein_coding None ENSG00000130943 missense T/I 1875 PKDREJ ENST00000253255.5:c.5624C>T ENSP00000253255.5:p.Thr1875Ile HLA-G*01:09 10 1 10 LYYSYGLLHI LYYSYGLLHT PickPocket 1469.28 2365.16 1.61 PickPocket 0.3 0.4 120 0.233 NA NA NA NA NA NA 1469.28 2365.16 1.61 0.3 0.4 NA NA NA NA 2365.16 1469.28 0.4 0.3 20.PKDREJ.ENST00000253255.5.missense.1875T/I False 0.9142857142857143 0.9142857142857143 False False False 0 False 0 +22 22550509 22550510 T G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense S/A 63 IGLV6-57 ENST00000390285.3:c.187T>G ENSP00000374820.3:p.Ser63Ala HLA-G*01:09 9 1 9 WYQQRPGSA WYQQRPGSS PickPocket 2781.92 3567.97 1.283 PickPocket 2.7 4.3 7 0.571 NA NA NA NA NA NA 2781.92 3567.97 1.283 2.7 4.3 NA NA NA NA 3567.97 2781.92 4.3 2.7 10.IGLV6-57.ENST00000390285.3.missense.63S/A False -1.7857142857142858 -1.7857142857142858 False False False 0 False 0 +22 39994238 39994239 G A ENST00000402142.3 Not Supported 2223 Not Run Not Run protein_coding None ENSG00000100346 missense C/Y 107 CACNA1I ENST00000402142.3:c.320G>A ENSP00000385019.3:p.Cys107Tyr HLA-G*01:09 10 1 10 MYQPCDDMDY MYQPCDDMDC PickPocket 2904.96 2873.7 0.989 PickPocket 0.5 0.5 92 0.043 NA NA NA NA NA NA 2904.96 2873.7 0.989 0.5 0.5 NA NA NA NA 2873.7 2904.96 0.5 0.5 17.CACNA1I.ENST00000402142.3.missense.107C/Y False -1.2857142857142858 -1.2857142857142858 False False False 1 False 0 +22 18644672 18644673 C T ENST00000215794.7 Not Supported 372 Not Run Not Run protein_coding None ENSG00000184979 missense A/V 124 USP18 ENST00000215794.7:c.371C>T ENSP00000215794.7:p.Ala124Val HLA-G*01:09 9 8 2 LVYCLQKCN LAYCLQKCN PickPocket 3099.81 6399.79 2.065 PickPocket 3.3 12.0 113 0.053 NA NA NA NA NA NA 3099.81 6399.79 2.065 3.3 12.0 NA NA NA NA 6399.79 3099.81 12.0 3.3 6.USP18.ENST00000215794.7.missense.124A/V False -0.4857142857142857 0.7999999999999999 False False False 2 False 0 +22 37771017 37771018 G A ENST00000402918.2 Not Supported 820 Not Run Not Run protein_coding None ENSG00000166897 missense P/L 186 ELFN2 ENST00000402918.2:c.557C>T ENSP00000385277.1:p.Pro186Leu HLA-G*01:09 9 1 9 MVCELAGNL MVCELAGNP PickPocket 3454.02 10191.11 2.951 PickPocket 4.1 21.0 303 0.135 NA NA NA NA NA NA 3454.02 10191.11 2.951 4.1 21.0 NA NA NA NA 10191.11 3454.02 21.0 4.1 13.ELFN2.ENST00000402918.2.missense.186P/L False 0.6428571428571427 1.4714285714285713 False False False 1 False 0 +22 50615580 50615581 C T ENST00000395842.2 Not Supported 677 Not Run Not Run protein_coding None ENSG00000073150 missense S/F 147 PANX2 ENST00000395842.2:c.440C>T ENSP00000379183.2:p.Ser147Phe HLA-G*01:09 9 8 2 AFTRLTSEL ASTRLTSEL PickPocket 3807.28 8387.64 2.203 PickPocket 4.8 16.0 171 0.959 NA NA NA NA NA NA 3807.28 8387.64 2.203 4.8 16.0 NA NA NA NA 8387.64 3807.28 16.0 4.8 22.PANX2.ENST00000395842.2.missense.147S/F False -0.3714285714285715 0.24285714285714272 False False False 0 False 0 +6 41754573 41754573 C CCTT ENST00000458694.1 Not Supported 384 Not Run Not Run protein_coding None ENSG00000124593 inframe_ins -/L 287-288 PRICKLE4 ENST00000458694.1:c.863_864insTCT ENSP00000404911.1:p.Leu288dup HLA-E*01:01 9 2 9 ATLSRTLLL ATLSRTLLA PickPocket 2122.61 3272.12 1.542 NetMHC 0.12 5.1 76 0.158 NA NA NA NA NA NA 3816.925 14131.865 3.702 0.51 3.8 24991.61 5511.24 5.1 0.12 3272.12 2122.61 2.5 0.9 3.PRICKLE4.ENST00000458694.1.inframe_ins.287-288-/L False 1.3142857142857143 1.3142857142857143 False False False 0 False 0 +22 50682229 50682230 T C ENST00000248846.5 Not Supported 1819 Not Run Not Run protein_coding None ENSG00000128159 missense H/R 220 TUBGCP6 ENST00000248846.5:c.659A>G ENSP00000248846.5:p.His220Arg HLA-G*01:09 9 9 1 RSRTYDMDV HSRTYDMDV PickPocket 4576.12 7609.38 1.663 PickPocket 6.3 15.0 210 0.686 NA NA NA NA NA NA 4576.12 7609.38 1.663 6.3 15.0 NA NA NA NA 7609.38 4576.12 15.0 6.3 23.TUBGCP6.ENST00000248846.5.missense.220H/R False -1.0571428571428572 -1.0571428571428572 False False False 0 False 0 +2 217498305 217498305 T TGCTGCC ENST00000233809.4 Not Supported 325 Not Run Not Run protein_coding None ENSG00000115457 inframe_ins L/LLP 20 IGFBP2 ENST00000233809.4:c.64_65insCGCTGC ENSP00000233809.4:p.Leu21_Leu22insProLeu HLA-E*01:01 9 6 6 LLPLLPLLL LLPLLLLLL PickPocket 2551.25 3099.81 1.215 NetMHC 0.17 0.33 101 0.891 NA NA NA NA NA NA 4721.43 6167.26 1.306 0.785 1.265 9234.71 6891.61 0.33 0.17 3099.81 2551.25 2.2 1.4 1.IGFBP2.ENST00000233809.4.inframe_ins.20L/LLP False 2.257142857142857 2.257142857142857 False False False 0 False 0 +22 19175521 19175522 G T ENST00000263200.10 Not Supported 1640 Not Run Not Run protein_coding None ENSG00000070371 missense H/N 1469 CLTCL1 ENST00000263200.10:c.4405C>A ENSP00000445677.1:p.His1469Asn HLA-G*01:09 9 2 8 SVNEALNNL SVNEALNHL PickPocket 4989.87 7775.84 1.558 PickPocket 7.3 15.0 30 0.1 NA NA NA NA NA NA 4989.87 7775.84 1.558 7.3 15.0 NA NA NA NA 7775.84 4989.87 15.0 7.3 7.CLTCL1.ENST00000263200.10.missense.1469H/N True -0.6571428571428573 -0.21428571428571427 False False False 0 False 0 +22 18020271 18020272 G A ENST00000262608.8 Not Supported 1443 Not Run Not Run protein_coding None ENSG00000099954 missense R/H 535 CECR2 ENST00000262608.8:c.1604G>A ENSP00000262608.8:p.Arg535His HLA-G*01:09 9 7 3 WTHSRDPEG WTRSRDPEG PickPocket 5500.22 19932.31 3.624 PickPocket 8.4 40.0 56 0.071 NA NA NA NA NA NA 5500.22 19932.31 3.624 8.4 40.0 NA NA NA NA 19932.31 5500.22 40.0 8.4 5.CECR2.ENST00000262608.8.missense.535R/H False -2.5 -2.1714285714285717 False False False 0 False 0 +22 50869713 50869714 C A ENST00000395741.3 Not Supported 933 Not Run Not Run protein_coding None ENSG00000100239 missense S/Y 414 PPP6R2 ENST00000395741.3:c.1241C>A ENSP00000379090.3:p.Ser414Tyr HLA-G*01:09 9 8 2 GYESRVEPP GSESRVEPP PickPocket 5620.54 22209.93 3.952 PickPocket 8.7 44.0 116 0.043 NA NA NA NA NA NA 5620.54 22209.93 3.952 8.7 44.0 NA NA NA NA 22209.93 5620.54 44.0 8.7 24.PPP6R2.ENST00000395741.3.missense.414S/Y False -1.6142857142857143 -1.4000000000000001 False False True 0 False 0 +22 20709231 20709232 G C ENST00000434783.3 Not Supported 905 Not Run Not Run protein_coding None ENSG00000188280 missense E/Q 322 FAM230A ENST00000434783.3:c.964G>C ENSP00000463576.1:p.Glu322Gln HLA-G*01:09 9 7 3 ANQDAAQGI ANEDAAQGI PickPocket 5681.68 9654.43 1.699 PickPocket 8.8 20.0 22 0.5 NA NA NA NA NA NA 5681.68 9654.43 1.699 8.8 20.0 NA NA NA NA 9654.43 5681.68 20.0 8.8 8.FAM230A.ENST00000434783.3.missense.322E/Q False -0.4000000000000001 -0.4000000000000001 False False False 0 False 0 +22 38027027 38027028 C G ENST00000343632.4 Not Supported 639 Not Run Not Run protein_coding None ENSG00000100083 missense P/A 484 GGA1 ENST00000343632.4:c.1450C>G ENSP00000341344.4:p.Pro484Ala HLA-E*01:01 9 9 1 ARPPQQPVP PRPPQQPVP PickPocket 1654.99 4242.33 2.563 PickPocket 0.4 4.8 245 0.486 NA NA NA NA NA NA 6693.895 10556.225 1.577 0.485 3.2 16870.12 11732.8 1.6 0.57 4242.33 1654.99 4.8 0.4 15.GGA1.ENST00000343632.4.missense.484P/A False -1.3142857142857143 -1.3142857142857143 False False True 0 False 0 +22 29886116 29886117 C A ENST00000310624.6 Not Supported 1020 Not Run Not Run protein_coding None ENSG00000100285 missense P/T 830 NEFH ENST00000310624.6:c.2488C>A ENSP00000311997.6:p.Pro830Thr HLA-G*01:09 9 8 2 KTQEVKVKE KPQEVKVKE PickPocket 7366.35 25842.4 3.508 PickPocket 14.0 50.0 185 0.038 NA NA NA NA NA NA 7366.35 25842.4 3.508 14.0 50.0 NA NA NA NA 25842.4 7366.35 50.0 14.0 12.NEFH.ENST00000310624.6.missense.830P/T False -1.4142857142857141 -1.014285714285714 False False False 0 False 0 +22 22550449 22550450 C G ENST00000390285.3 Not Supported 148 Not Run Not Run IG_V_gene None ENSG00000211640 missense R/G 43 IGLV6-57 ENST00000390285.3:c.127C>G ENSP00000374820.3:p.Arg43Gly HLA-G*01:09 9 1 9 KTVTISCTG KTVTISCTR PickPocket 9447.76 15208.39 1.61 PickPocket 19.0 31.0 5 1.0 NA NA NA NA NA NA 9447.76 15208.39 1.61 19.0 31.0 NA NA NA NA 15208.39 9447.76 31.0 19.0 9.IGLV6-57.ENST00000390285.3.missense.43R/G False 1.2285714285714284 1.2285714285714284 False False False 1 False 0 +22 41895790 41895791 C A ENST00000216254.4 Not Supported 780 Not Run Not Run protein_coding None ENSG00000100412 missense A/E 33 ACO2 ENST00000216254.4:c.98C>A ENSP00000216254.4:p.Ala33Glu HLA-G*01:09 9 2 8 LCQRAKVEM LCQRAKVAM PickPocket 9972.95 15710.15 1.575 PickPocket 21.0 33.0 113 0.044 NA NA NA NA NA NA 9972.95 15710.15 1.575 21.0 33.0 NA NA NA NA 15710.15 9972.95 33.0 21.0 18.ACO2.ENST00000216254.4.missense.33A/E False -1.0714285714285712 0.0571428571428572 False False False 1 False 0 +22 50555769 50555770 G A ENST00000262794.5 Not Supported 1211 Not Run Not Run protein_coding None ENSG00000073146 missense A/T 482 MOV10L1 ENST00000262794.5:c.1444G>A ENSP00000262794.5:p.Ala482Thr HLA-G*01:09 9 2 8 KTTVVVTTQ KTTVVVTAQ PickPocket 10874.65 16763.86 1.542 PickPocket 23.0 34.0 96 0.042 NA NA NA NA NA NA 10874.65 16763.86 1.542 23.0 34.0 NA NA NA NA 16763.86 10874.65 34.0 23.0 21.MOV10L1.ENST00000262794.5.missense.482A/T False 1.0000000000000002 1.4000000000000001 False False False 0 False 0 +22 38119219 38119220 GA G ENST00000406386.3 Not Supported 2365 Not Run Not Run protein_coding None ENSG00000100106 FS G/X 219 TRIOBP ENST00000406386.3:c.657del ENSP00000384312.3:p.Gln220SerfsTer21 HLA-G*01:09 9 19 NA AGCPWSGTG NA PickPocket 13501.89 NA NA PickPocket 28.0 NA 142 0.768 NA NA NA NA NA NA 13501.89 NA NA 28.0 NA NA NA NA NA NA 13501.89 NA 28.0 16.TRIOBP.ENST00000406386.3.FS.219GA/G False -0.3285714285714286 0.02857142857142855 False False False 1 False 0 +22 37966274 37966275 C G ENST00000215886.4 Not Supported 132 Not Run Not Run protein_coding None ENSG00000100079 missense E/Q 132 LGALS2 ENST00000215886.4:c.394G>C ENSP00000215886.4:p.Glu132Gln HLA-E*01:01 9 9 9 NMSSFKLKQ NMSSFKLKE PickPocket 3890.57 3848.7 0.989 PickPocket 4.0 3.9 117 0.496 NA NA NA NA NA NA 17113.26 17432.18 1.019 8.0 8.45 31015.66 30335.95 13.0 12.0 3848.7 3890.57 3.9 4.0 14.LGALS2.ENST00000215886.4.missense.132E/Q False -0.9000000000000001 -0.07142857142857155 False False False 0 True 0 +22 26936775 26936776 G T ENST00000338754.4 Not Supported 377 Not Run Not Run protein_coding None ENSG00000128294 missense P/H 274 TPST2 ENST00000338754.4:c.821C>A ENSP00000339813.4:p.Pro274His HLA-E*01:01 9 6 4 IGKHGGVSL IGKPGGVSL PickPocket 9447.76 7945.94 0.841 NetMHC 6.9 1.3 140 0.179 NA NA NA NA NA NA 18405.335 11610.23 0.631 14.95 9.65 15274.52 27362.91 1.3 6.9 7945.94 9447.76 18.0 23.0 11.TPST2.ENST00000338754.4.missense.274P/H False -0.10000000000000002 0.05714285714285713 False False False 0 False 0 +4 40434704 40434725 AGCGGCTGCGGCGGCTGCGGCC A ENST00000381793.2 Not Supported 593 Not Run Not Run protein_coding None ENSG00000163694 inframe_del AAAAAAAA/A 495-502 RBM47 ENST00000381793.2:c.1485_1505del ENSP00000371212.2:p.Ala496_Ala502del HLA-E*01:01 9 2 9 SAAAAAAAV SAAAAAAAA PickPocket 21040.32 21040.32 1.0 NetMHC 21.0 30.0 128 0.977 NA NA NA NA NA NA 28125.2 29506.67 1.049 38.0 42.5 37973.02 35210.08 30.0 21.0 21040.32 21040.32 55.0 55.0 2.RBM47.ENST00000381793.2.inframe_del.495-502AAAAAAAA/A False 2.142857142857143 2.142857142857143 False False False 0 False 0 diff --git a/tests/test_data/top_score_filter/output_pvacsplice.tsv b/tests/test_data/top_score_filter/output_pvacsplice.tsv index ef55751b6..46353078d 100644 --- a/tests/test_data/top_score_filter/output_pvacsplice.tsv +++ b/tests/test_data/top_score_filter/output_pvacsplice.tsv @@ -1,15 +1,15 @@ -Chromosome Start Stop Reference Variant Junction Junction Start Junction Stop Junction Score Junction Anchor Transcript Transcript Support Level Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Amino Acid Change Gene Name HGVSc HGVSp WT Protein Length ALT Protein Length Frameshift Event Protein Position HLA Allele Peptide Length Epitope Seq Median IC50 Score Best IC50 Score Best IC50 Score Method Median Percentile Best Percentile Best Percentile Method Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Index Fasta Key NetMHC IC50 Score NetMHC Percentile PickPocket IC50 Score PickPocket Percentile Problematic Positions cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-G*01:09 9 KNPAWVWLW 5099.03 5099.03 PickPocket 7.5 7.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 38 NA NA 5099.03 7.5 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-G*01:09 9 KNPAWVWLW 5099.03 5099.03 PickPocket 7.5 7.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 38 NA NA 5099.03 7.5 None 0.7857142857142857 0.7857142857142857 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 9759.45 20.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 9759.45 20.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 9759.45 20.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 12 NA NA 9759.45 20.0 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 26 HLA-G*01:09 10 HIMKSADVVN 11857.88 11857.88 PickPocket 6.8 6.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 27 NA NA 11857.88 6.8 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 26 HLA-G*01:09 10 HIMKSADVVN 11857.88 11857.88 PickPocket 6.8 6.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 27 NA NA 11857.88 6.8 None -0.21428571428571427 0.6000000000000002 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 27 HLA-E*01:01 10 IMKSADVVKV 19498.205 7692.16 PickPocket 7.2 1.4 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 18 31304.25 13.0 7692.16 1.4 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 27 HLA-E*01:01 10 IMKSADVVKV 19498.205 7692.16 PickPocket 7.2 1.4 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 18 31304.25 13.0 7692.16 1.4 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +Chromosome Start Stop Reference Variant Junction Junction Start Junction Stop Junction Score Junction Anchor Transcript Transcript Support Level Canonical MANE Select Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Amino Acid Change Gene Name HGVSc HGVSp WT Protein Length ALT Protein Length Frameshift Event Protein Position HLA Allele Peptide Length Epitope Seq Median IC50 Score Best IC50 Score Best IC50 Score Method Median Percentile Best Percentile Best Percentile Method Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Index Fasta Key NetMHC IC50 Score NetMHC Percentile PickPocket IC50 Score PickPocket Percentile Problematic Positions Gene of Interest cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 39 HLA-G*01:09 9 KNPAWVWLW 5099.03 5099.03 PickPocket 7.5 7.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 NA NA 5099.03 7.5 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 39 HLA-G*01:09 9 KNPAWVWLW 5099.03 5099.03 PickPocket 7.5 7.5 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 38 NA NA 5099.03 7.5 None False 0.7857142857142857 0.7857142857142857 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 9759.45 20.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 9759.45 20.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 9759.45 20.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-G*01:09 9 KSEEKELKI 9759.45 9759.45 PickPocket 20.0 20.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 NA NA 9759.45 20.0 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 26 HLA-G*01:09 10 HIMKSADVVN 11857.88 11857.88 PickPocket 6.8 6.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 27 NA NA 11857.88 6.8 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 26 HLA-G*01:09 10 HIMKSADVVN 11857.88 11857.88 PickPocket 6.8 6.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 27 NA NA 11857.88 6.8 None False -0.21428571428571427 0.6000000000000002 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 27 HLA-E*01:01 10 IMKSADVVKV 19498.205 7692.16 PickPocket 7.2 1.4 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 31304.25 13.0 7692.16 1.4 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 27 HLA-E*01:01 10 IMKSADVVKV 19498.205 7692.16 PickPocket 7.2 1.4 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 18 31304.25 13.0 7692.16 1.4 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 diff --git a/tests/test_data/top_score_filter/output_pvacsplice_percentile.tsv b/tests/test_data/top_score_filter/output_pvacsplice_percentile.tsv index 6f0368166..27a42028c 100644 --- a/tests/test_data/top_score_filter/output_pvacsplice_percentile.tsv +++ b/tests/test_data/top_score_filter/output_pvacsplice_percentile.tsv @@ -1,15 +1,15 @@ -Chromosome Start Stop Reference Variant Junction Junction Start Junction Stop Junction Score Junction Anchor Transcript Transcript Support Level Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Amino Acid Change Gene Name HGVSc HGVSp WT Protein Length ALT Protein Length Frameshift Event Protein Position HLA Allele Peptide Length Epitope Seq Median IC50 Score Best IC50 Score Best IC50 Score Method Median Percentile Best Percentile Best Percentile Method Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Index Fasta Key NetMHC IC50 Score NetMHC Percentile PickPocket IC50 Score PickPocket Percentile Problematic Positions cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-G*01:09 10 RFKNPAWVWL 5620.54 5620.54 PickPocket 1.8 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D 39 NA NA 5620.54 1.8 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-G*01:09 10 RFKNPAWVWL 5620.54 5620.54 PickPocket 1.8 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D 39 NA NA 5620.54 1.8 None 0.41428571428571426 0.41428571428571426 False False False 0 False 1 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D 12 37753.86 30.0 2812.19 1.7 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D 12 37753.86 30.0 2812.19 1.7 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D 12 37753.86 30.0 2812.19 1.7 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D 12 37753.86 30.0 2812.19 1.7 None -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-E*01:01 9 MKSADVVKV 21064.155 8119.76 PickPocket 18.0 18.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D 16 34008.55 18.0 8119.76 18.0 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-E*01:01 9 MKSADVVKV 21064.155 8119.76 PickPocket 18.0 18.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D 16 34008.55 18.0 8119.76 18.0 None 0.8857142857142859 0.8857142857142859 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-E*01:01 10 IMKSADVVNR 23794.95 8297.38 PickPocket 18.8 1.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 20.289 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D 28 39292.52 36.0 8297.38 1.6 None -0.29999999999999993 0.6000000000000002 False False False 0 False 0 -chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-E*01:01 10 IMKSADVVNR 23794.95 8297.38 PickPocket 18.8 1.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.746 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D 28 39292.52 36.0 8297.38 1.6 None -0.29999999999999993 0.6000000000000002 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 -chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA 1 NA NA 14882.82 31.0 None -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +Chromosome Start Stop Reference Variant Junction Junction Start Junction Stop Junction Score Junction Anchor Transcript Transcript Support Level Canonical MANE Select Biotype Transcript CDS Flags Ensembl Gene ID Variant Type Amino Acid Change Gene Name HGVSc HGVSp WT Protein Length ALT Protein Length Frameshift Event Protein Position HLA Allele Peptide Length Epitope Seq Median IC50 Score Best IC50 Score Best IC50 Score Method Median Percentile Best Percentile Best Percentile Method Tumor DNA Depth Tumor DNA VAF Tumor RNA Depth Tumor RNA VAF Normal Depth Normal VAF Gene Expression Transcript Expression Index Fasta Key NetMHC IC50 Score NetMHC Percentile PickPocket IC50 Score PickPocket Percentile Problematic Positions Gene of Interest cterm_7mer_gravy_score max_7mer_gravy_score difficult_n_terminal_residue c_terminal_cysteine c_terminal_proline cysteine_count n_terminal_asparagine asparagine_proline_bond_count +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 48 yes 37 HLA-G*01:09 10 RFKNPAWVWL 5620.54 5620.54 PickPocket 1.8 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 NA NA 5620.54 1.8 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 168179177 168179178 A T JUNC00000028 168179181 168183952 12 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 48 yes 37 HLA-G*01:09 10 RFKNPAWVWL 5620.54 5620.54 PickPocket 1.8 1.8 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000028.chr1:168179177-168179178.D.frameshift_splice_site 39 NA NA 5620.54 1.8 None False 0.41428571428571426 0.41428571428571426 False False False 0 False 1 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1449 no 760 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 37753.86 30.0 2812.19 1.7 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1449 no 760 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 37753.86 30.0 2812.19 1.7 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1294 no 761 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 37753.86 30.0 2812.19 1.7 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000011 93226449 93232441 14 D ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1450 no 761 HLA-E*01:01 9 KSEEKELKI 20283.025 2812.19 PickPocket 15.85 1.7 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000011.chr1:93226448-93226449.D.inframe_splice_site 12 37753.86 30.0 2812.19 1.7 None False -1.4285714285714288 -1.4285714285714288 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 44 yes 28 HLA-E*01:01 9 MKSADVVKV 21064.155 8119.76 PickPocket 18.0 18.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 16 34008.55 18.0 8119.76 18.0 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000025 168179181 168183411 29 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 44 yes 28 HLA-E*01:01 9 MKSADVVKV 21064.155 8119.76 PickPocket 18.0 18.0 NetMHC 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000025.chr1:168179177-168179178.D.frameshift_splice_site 16 34008.55 18.0 8119.76 18.0 None False 0.8857142857142859 0.8857142857142859 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367830.3 1 False False protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367830.3:c.101A>T ENSP00000356804.3:p.Glu34Val 178 36 yes 27 HLA-E*01:01 10 IMKSADVVNR 23794.95 8297.38 PickPocket 18.8 1.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 20.287 TIPRL.ENST00000367830.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 28 39292.52 36.0 8297.38 1.6 None False -0.29999999999999993 0.6000000000000002 False False False 0 False 0 +chr1 168179177 168179178 A T JUNC00000027 168179181 168183907 73 D ENST00000367833.7 1 True True protein_coding None TIPRL missense_variant E/V TIPRL ENST00000367833.7:c.101A>T ENSP00000356807.2:p.Glu34Val 272 36 yes 27 HLA-E*01:01 10 IMKSADVVNR 23794.95 8297.38 PickPocket 18.8 1.6 PickPocket 176 0.273 927.0 0.332 153 0.0 55.745 35.458 TIPRL.ENST00000367833.JUNC00000027.chr1:168179177-168179178.D.frameshift_splice_site 28 39292.52 36.0 8297.38 1.6 None False -0.29999999999999993 0.6000000000000002 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000343253.11 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000343253.11:c.2289G>A ENSP00000343377.7:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 1.033 CCDC18.ENST00000343253.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000370276.6 5 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000370276.6:c.2289G>A ENSP00000359299.2:p.Glu763= 1454 1415 no 718 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 0.0 CCDC18.ENST00000370276.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000401026.7 1 False False protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000401026.7:c.2292G>A ENSP00000383808.3:p.Glu764= 1299 1260 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.225 CCDC18.ENST00000401026.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 +chr1 93226448 93226449 G A JUNC00000006 93221936 93232426 181 NDA ENST00000690025.1 NA True True protein_coding None CCDC18 splice_region_variant&synonymous_variant E CCDC18 ENST00000690025.1:c.2292G>A ENSP00000510597.1:p.Glu764= 1455 1416 no 719 HLA-G*01:09 9 VSEETIKVY 14882.82 14882.82 PickPocket 31.0 31.0 PickPocket 148 0.628 20.0 0.3 112 0.0 18.75 2.646 CCDC18.ENST00000690025.JUNC00000006.chr1:93226448-93226449.NDA.inframe_splice_site 1 NA NA 14882.82 31.0 None False -0.5999999999999999 -0.5285714285714286 False False False 0 False 0 From 25421841d876a85845232427603738025cbdf698 Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Wed, 22 Oct 2025 10:08:32 -0500 Subject: [PATCH 06/11] Include mane select, canonical, and cds flag information in pVACview transcript table --- pvactools/tools/pvacview/server.R | 8 ++++++-- 1 file changed, 6 insertions(+), 2 deletions(-) diff --git a/pvactools/tools/pvacview/server.R b/pvactools/tools/pvacview/server.R index e2c3086b4..30bfc4198 100644 --- a/pvactools/tools/pvacview/server.R +++ b/pvactools/tools/pvacview/server.R @@ -956,19 +956,23 @@ server <- shinyServer(function(input, output, session) { if (length(df$metricsData[[selectedID()]]$sets) != 0) { GB_transcripts <- data.frame("Transcripts" = df$metricsData[[selectedID()]]$good_binders[[selectedTranscriptSet()]]$`transcripts`, "Expression" = df$metricsData[[selectedID()]]$good_binders[[selectedTranscriptSet()]]$`transcript_expr`, + "MANE Select" = df$metricsData[[selectedID()]]$good_binders[[selectedTranscriptSet()]]$`mane_select`, + "Canonical" = df$metricsData[[selectedID()]]$good_binders[[selectedTranscriptSet()]]$`canonical`, "TSL" = df$metricsData[[selectedID()]]$good_binders[[selectedTranscriptSet()]]$`tsl`, "Biotype" = df$metricsData[[selectedID()]]$good_binders[[selectedTranscriptSet()]]$`biotype`, + "CDS Flags" = df$metricsData[[selectedID()]]$good_binders[[selectedTranscriptSet()]]$`transcript_cds_flags`, "Length" = df$metricsData[[selectedID()]]$good_binders[[selectedTranscriptSet()]]$`transcript_length`) GB_transcripts$`Best Transcript` <- apply(GB_transcripts, 1, function(x) grepl(best_transcript, x["Transcripts"], fixed = TRUE)) incProgress(0.5) - names(GB_transcripts) <- c("Transcripts in Selected Set", "Expression", "Transcript Support Level", "Biotype", "Transcript Length (#AA)", "Best Transcript") + names(GB_transcripts) <- c("Transcripts in Selected Set", "Expression", "MANE Select", "Canonical", "Transcript Support Level", "Biotype", "CDS Flags", "Transcript Length (#AA)", "Best Transcript") incProgress(0.5) datatable(GB_transcripts, options = list(columnDefs = list(list(defaultContent = "N/A", targets = c(3)), list(visible = FALSE, targets = c(-1))))) %>% formatStyle(c("Transcripts in Selected Set"), "Best Transcript", backgroundColor = styleEqual(c(TRUE), c("#98FF98"))) }else { - GB_transcripts <- data.frame("Transcript" = character(), "Expression" = character(), "TSL" = character(), "Biotype" = character(), "Transcript Length (#AA)"= character(), "Length" = character()) + GB_transcripts <- data.frame("Transcript" = character(), "Expression" = character(), "MANE Select" = character(), "Canonical" = character(),"TSL" = character(), "Biotype" = character(), "Transcript Length (#AA)"= character(), "Length" = character()) incProgress(0.5) names(GB_transcripts) <- c("Transcripts in Selected Set", "Expression", "Transcript Support Level", "Biotype", "Transcript Length (#AA)", "Best Transcript") + names(GB_transcripts) <- c("Transcripts in Selected Set", "Expression", "MANE Select", "Canonical", "Transcript Support Level", "Biotype", "CDS Flags", "Transcript Length (#AA)", "Best Transcript") incProgress(0.5) datatable(GB_transcripts) } From 7844557486ab858d5557f79fdb6af91db2b070c0 Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Fri, 24 Oct 2025 14:07:30 -0500 Subject: [PATCH 07/11] Fix defaultContent in transcript table to apply to TSL column --- pvactools/tools/pvacview/server.R | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/pvactools/tools/pvacview/server.R b/pvactools/tools/pvacview/server.R index 30bfc4198..6ecdbd734 100644 --- a/pvactools/tools/pvacview/server.R +++ b/pvactools/tools/pvacview/server.R @@ -966,7 +966,7 @@ server <- shinyServer(function(input, output, session) { incProgress(0.5) names(GB_transcripts) <- c("Transcripts in Selected Set", "Expression", "MANE Select", "Canonical", "Transcript Support Level", "Biotype", "CDS Flags", "Transcript Length (#AA)", "Best Transcript") incProgress(0.5) - datatable(GB_transcripts, options = list(columnDefs = list(list(defaultContent = "N/A", targets = c(3)), list(visible = FALSE, targets = c(-1))))) %>% + datatable(GB_transcripts, options = list(columnDefs = list(list(defaultContent = "NA", targets = c(5)), list(visible = FALSE, targets = c(-1))))) %>% formatStyle(c("Transcripts in Selected Set"), "Best Transcript", backgroundColor = styleEqual(c(TRUE), c("#98FF98"))) }else { GB_transcripts <- data.frame("Transcript" = character(), "Expression" = character(), "MANE Select" = character(), "Canonical" = character(),"TSL" = character(), "Biotype" = character(), "Transcript Length (#AA)"= character(), "Length" = character()) From 05a14f571c59ec1a31f32cbe2a3dfb33f9902366 Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Tue, 28 Oct 2025 11:16:07 -0500 Subject: [PATCH 08/11] Fix pvactools compare commandline help --- pvactools/tools/compare.py | 2 ++ 1 file changed, 2 insertions(+) diff --git a/pvactools/tools/compare.py b/pvactools/tools/compare.py index b8532c468..ac55b810b 100644 --- a/pvactools/tools/compare.py +++ b/pvactools/tools/compare.py @@ -123,6 +123,8 @@ def define_parser(): default_reference_match_columns = ["Peptide", "Match Window"] parser = argparse.ArgumentParser( + "pvactools compare", + description="Run a comparison between two output results folders", formatter_class=argparse.ArgumentDefaultsHelpFormatter ) parser.add_argument( From 5b43da54ba55c468e63197bb7a12c8cde83700bd Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Wed, 29 Oct 2025 10:01:59 -0500 Subject: [PATCH 09/11] Fix incorrect default value for parsed mane_select field --- pvactools/lib/input_file_converter.py | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/pvactools/lib/input_file_converter.py b/pvactools/lib/input_file_converter.py index 53730a140..7f8ee4236 100644 --- a/pvactools/lib/input_file_converter.py +++ b/pvactools/lib/input_file_converter.py @@ -647,7 +647,7 @@ def execute(self): else: output_row['mane_select'] = 'True' else: - output_row['mane_select'] = 'Not Supported' + output_row['mane_select'] = 'Not Run' for (tag, key, comparison_fields) in zip(['TX', 'GX'], ['transcript_expression', 'gene_expression'], [[transcript_name], [ensembl_gene_id, gene_name]]): if tag in self.vcf_reader.header.format_ids(): From 64f884f20571d892195678598e15b4f138f1655a Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Thu, 30 Oct 2025 08:45:29 -0500 Subject: [PATCH 10/11] Fix main pVACview table header tooltips --- pvactools/tools/pvacview/styling.R | 12 +++++++----- 1 file changed, 7 insertions(+), 5 deletions(-) diff --git a/pvactools/tools/pvacview/styling.R b/pvactools/tools/pvacview/styling.R index 24b38eb16..598bbacd7 100644 --- a/pvactools/tools/pvacview/styling.R +++ b/pvactools/tools/pvacview/styling.R @@ -16,15 +16,17 @@ callback <- function(hla_count, score_mode) { " 'Num Passing Transcripts - The number of transcripts for this mutation that resulted in at least one well-binding peptide.',", " 'Best Peptide - The best-binding mutant epitope sequence (lowest mutant binding affinity) prioritizing epitope sequences that resulted from a protein_coding transcript with a TSL below the maximum transcript support level and having no problematic positions.',", " 'Best Transcript - Transcript corresponding to the best peptide with the lowest TSL and shortest length.',", - " 'TSL - Transcript support level of the best peptide.',", + " 'MANE Select - MANE select status of the best transcript.',", + " 'Canonical - Canonical status of the best transcript.',", + " 'TSL - Transcript support level of the best transcript.',", " 'Allele',", " 'Pos - The one-based position of the start of the mutation within the epitope sequence. 0 if the start of the mutation is before the epitope (as can occur downstream of frameshift mutations).',", " 'Prob Pos - Problematic positions within the best peptide.',", " 'Num Included Peptides - The number of top-scoring, unique peptides included for review.',", " 'Num Passing Peptides - The number of unique well-binding peptides for this mutation.',", - gsub("X", score_mode," 'IC50 MT - X IC50 binding affinity of the best-binding mutant epitope across all prediction algorithms used.', "), + paste(" 'IC50 MT -", score_mode, "IC50 binding affinity of the best-binding mutant epitope across all prediction algorithms used.', "), " 'IC50 WT - IC50 binding affinity of the corresponding wildtype epitope.',", - gsub("X", score_mode," '%ile MT - X binding affinity percentile rank of the best-binding mutant epitope across all prediction algorithms used (those that provide percentile output).', "), + paste(" '%ile MT - ", score_mode, "binding affinity percentile rank of the best-binding mutant epitope across all prediction algorithms used (those that provide percentile output).', "), " '%ile WT - Binding affinity percentile rank of the corresponding wildtype epitope across all prediction algorithms used (those that provide percentile output).', ", " 'RNA Expr - Gene expression value for the annotated gene containing the variant.',", " 'RNA VAF - Tumor RNA variant allele frequency (VAF) at this position.',", @@ -37,8 +39,8 @@ callback <- function(hla_count, score_mode) { " 'Rej - Click the thumbs-down button to reject a neoantigen candidate.',", " 'Rev - Click the flag button to mark a neoantigen candidate for review.'],", "header = table.columns().header();", - gsub("7", hla_count, "for (var i = 7; i-7 < tips.length; i++) {"), - gsub("7", hla_count, "$(header[i]).attr('title', tips[i-7]);"), + paste("for (var i = ", hla_count+1, "; i-", hla_count+1, " < tips.length; i++) {"), + paste("$(header[i]).attr('title', tips[i-", hla_count+1, "]);"), "}" ) } From ed415c01f5d8501acff625b9b7e3718d86ead2cb Mon Sep 17 00:00:00 2001 From: Susanna Kiwala Date: Fri, 31 Oct 2025 14:46:41 -0500 Subject: [PATCH 11/11] Fix pVACview main table Pos column not defaulting to NA --- pvactools/tools/pvacview/server.R | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/pvactools/tools/pvacview/server.R b/pvactools/tools/pvacview/server.R index 6ecdbd734..156f36aae 100644 --- a/pvactools/tools/pvacview/server.R +++ b/pvactools/tools/pvacview/server.R @@ -631,7 +631,7 @@ server <- shinyServer(function(input, output, session) { hla_columns <- which(colnames(filtered_table) %in% df$converted_hla_names) # Columns where the default value should be 'NA' - default_na_targets <- which(colnames(filtered_table) %in% c("POS", "IC50 WT", "%ile MT", "%ile WT", "RNA Expr", "RNA VAF", "Allele Expr", + default_na_targets <- which(colnames(filtered_table) %in% c("Pos", "IC50 WT", "%ile MT", "%ile WT", "RNA Expr", "RNA VAF", "Allele Expr", "RNA Depth", "DNA VAF")) # Columns that should be hidden from the display