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GitHub License GitHub repo size Documentation pLAST server Figshare data PyPI - Version


pLAST

pLAST is a computational tool for rapid comparison and classification of plasmid sequences based on their ORF composition.

It supports:

  • Similarity search against plasmid databases using a single query
  • Clustering of large plasmid datasets
  • Fast and scalable comparative analysis

🌐 pLAST Web Interface

The online pLAST server is available here:
👉 https://plast.lbs.cent.uw.edu.pl/

It provides a convenient graphical interface for running searches and visualizing results without installing the software locally.


🛠️ Installation

Basic installation

pLAST requires Python version 3.9 to 3.12. You can install pLAST directly using:

pip install plast

🛠️ Full Installation Guide

Detailed installation instructions, including dependencies, environment setup, and optional components, are available in the documentation:
👉 Installation Documentation


🧪 Usage Examples

A collection of usage examples demonstrating how to run pLAST, perform searches, and analyze results is available at the following link:
👉 Usage Examples

These examples provide step-by-step instructions and practical workflows to help you get started quickly.


📊 Data Availability

All datasets used in the project are publicly available on Figshare: 👉 https://doi.org/10.6084/m9.figshare.30530819.v2 👉 https://doi.org/10.6084/m9.figshare.30715637.v1


📚 Documentation

Complete project documentation, including tutorials, examples, and API reference, is available at:
👉 https://labstructbioinf.github.io/pLAST


📄 Citation

If you use pLAST in your research, please cite:

pLAST – a tool for rapid comparison and classification of plasmid sequences
Kamil Krakowski, Małgorzata Orłowska, Kamil Kamiński, Dariusz Bartosik, and Stanisław Dunin-Horkawicz
Publication in preparation.