diff --git a/stubs/setuptools/setuptools/_distutils/cmd.pyi b/stubs/setuptools/setuptools/_distutils/cmd.pyi
index 2c22e460989c..036bb08441f8 100644
--- a/stubs/setuptools/setuptools/_distutils/cmd.pyi
+++ b/stubs/setuptools/setuptools/_distutils/cmd.pyi
@@ -1,7 +1,7 @@
 from _typeshed import BytesPath, StrOrBytesPath, StrPath, Unused
 from abc import abstractmethod
-from collections.abc import Callable, MutableSequence
-from typing import Any, ClassVar, TypeVar, overload
+from collections.abc import Callable, MutableSequence, Sequence
+from typing import Any, ClassVar, Literal, TypeVar, overload
 from typing_extensions import TypeVarTuple, Unpack
 
 from .dist import Distribution
@@ -84,7 +84,10 @@ class Command:
     def move_file(self, src: StrPath, dst: _StrPathT, level: Unused = 1) -> _StrPathT | str: ...
     @overload
     def move_file(self, src: BytesPath, dst: _BytesPathT, level: Unused = 1) -> _BytesPathT | bytes: ...
-    def spawn(self, cmd: MutableSequence[str], search_path: bool = True, level: Unused = 1) -> None: ...
+    @overload
+    def spawn(self, cmd: Sequence[StrOrBytesPath], search_path: Literal[False], level: Unused = 1) -> None: ...
+    @overload
+    def spawn(self, cmd: MutableSequence[bytes | StrPath], search_path: Literal[True] = True, level: Unused = 1) -> None: ...
     @overload
     def make_archive(
         self,
diff --git a/stubs/setuptools/setuptools/_distutils/compilers/C/base.pyi b/stubs/setuptools/setuptools/_distutils/compilers/C/base.pyi
index f33e86e6ba9f..8f51b6790596 100644
--- a/stubs/setuptools/setuptools/_distutils/compilers/C/base.pyi
+++ b/stubs/setuptools/setuptools/_distutils/compilers/C/base.pyi
@@ -1,5 +1,6 @@
-from _typeshed import BytesPath, Incomplete, StrPath, Unused
+from _typeshed import BytesPath, Incomplete, StrOrBytesPath, StrPath, Unused
 from collections.abc import Callable, Iterable, MutableSequence, Sequence
+from subprocess import _ENV
 from typing import ClassVar, Final, Literal, TypeVar, overload
 from typing_extensions import TypeAlias, TypeVarTuple, Unpack
 
@@ -172,7 +173,12 @@ class Compiler:
     def execute(
         self, func: Callable[[Unpack[_Ts]], Unused], args: tuple[Unpack[_Ts]], msg: str | None = None, level: int = 1
     ) -> None: ...
-    def spawn(self, cmd: MutableSequence[bytes | StrPath]) -> None: ...
+    @overload
+    def spawn(self, cmd: Sequence[StrOrBytesPath], *, search_path: Literal[False], env: _ENV | None = None) -> None: ...
+    @overload
+    def spawn(
+        self, cmd: MutableSequence[bytes | StrPath], *, search_path: Literal[True] = True, env: _ENV | None = None
+    ) -> None: ...
     def mkpath(self, name: str, mode: int = 0o777) -> None: ...
     @overload
     def move_file(self, src: StrPath, dst: _StrPathT) -> _StrPathT | str: ...
diff --git a/stubs/setuptools/setuptools/_distutils/compilers/C/msvc.pyi b/stubs/setuptools/setuptools/_distutils/compilers/C/msvc.pyi
index 44f5c85b8be3..ad2f16eb7d14 100644
--- a/stubs/setuptools/setuptools/_distutils/compilers/C/msvc.pyi
+++ b/stubs/setuptools/setuptools/_distutils/compilers/C/msvc.pyi
@@ -1,3 +1,5 @@
+from _typeshed import StrPath
+from collections.abc import Sequence
 from typing import ClassVar, Final
 
 from . import base
@@ -17,3 +19,4 @@ class Compiler(base.Compiler):
     def initialize(self, plat_name: str | None = None) -> None: ...
     @property
     def out_extensions(self) -> dict[str, str]: ...
+    def spawn(self, cmd: Sequence[bytes | StrPath]): ...  # type: ignore[override] # Less params
diff --git a/stubs/setuptools/setuptools/_distutils/spawn.pyi b/stubs/setuptools/setuptools/_distutils/spawn.pyi
index 259a3a99d23b..9b725d43a63d 100644
--- a/stubs/setuptools/setuptools/_distutils/spawn.pyi
+++ b/stubs/setuptools/setuptools/_distutils/spawn.pyi
@@ -1,11 +1,21 @@
-from _typeshed import StrPath
-from collections.abc import MutableSequence
+from _typeshed import StrOrBytesPath, StrPath, Unused
+from collections.abc import MutableSequence, Sequence
 from subprocess import _ENV
+from typing import Literal, overload
 
+@overload
+def spawn(
+    cmd: Sequence[StrOrBytesPath],
+    search_path: Literal[False],
+    verbose: Unused = False,
+    dry_run: bool = False,
+    env: _ENV | None = None,
+) -> None: ...
+@overload
 def spawn(
     cmd: MutableSequence[bytes | StrPath],
-    search_path: bool = True,
-    verbose: bool = False,
+    search_path: Literal[True] = True,
+    verbose: Unused = False,
     dry_run: bool = False,
     env: _ENV | None = None,
 ) -> None: ...